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2023

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Ageism By A Community Sample Of Young Adults: Expanding The Contact Hypothesis To Explore Ageism, Helena Lucia Swanson Nov 2023

Ageism By A Community Sample Of Young Adults: Expanding The Contact Hypothesis To Explore Ageism, Helena Lucia Swanson

College of Science and Health Theses and Dissertations

Aging demographics globally are changing rapidly, resulting in the category of “older adults” (65 years and older) growing to eventually become the largest age demographic (United Nations, 2022). As our world gets older, ageism is a growing concern given its health, societal, cultural, and political consequences (Chrisler et al., 2016; Bugental & Hehman, 2007; Levy et al., 2020). Following Allport’s Contact Hypothesis (1954), this dissertation empirically analyzed predictors of ageism, including contact with older adults, for younger adults (18-26 years old) residing in U.S. communities. Participants were recruited using Prolific Academic, an online crowdsourcing platform and responded to five scales …


Association Between Microbiome And The Development Of Adverse Posttraumatic Neuropsychiatric Sequelae After Traumatic Stress Exposure, Abigail L Zeamer, Stacey L House, Et Al. Nov 2023

Association Between Microbiome And The Development Of Adverse Posttraumatic Neuropsychiatric Sequelae After Traumatic Stress Exposure, Abigail L Zeamer, Stacey L House, Et Al.

2020-Current year OA Pubs

Patients exposed to trauma often experience high rates of adverse post-traumatic neuropsychiatric sequelae (APNS). The biological mechanisms promoting APNS are currently unknown, but the microbiota-gut-brain axis offers an avenue to understanding mechanisms as well as possibilities for intervention. Microbiome composition after trauma exposure has been poorly examined regarding neuropsychiatric outcomes. We aimed to determine whether the gut microbiomes of trauma-exposed emergency department patients who develop APNS have dysfunctional gut microbiome profiles and discover potential associated mechanisms. We performed metagenomic analysis on stool samples (n = 51) from a subset of adults enrolled in the Advancing Understanding of RecOvery afteR traumA …


Optimizing Sitter Use: Enhancing Safety And Cutting Costs, Lauren Gentry, Susan Perusich, Kristie Geil, Rachelle Lancaster Nov 2023

Optimizing Sitter Use: Enhancing Safety And Cutting Costs, Lauren Gentry, Susan Perusich, Kristie Geil, Rachelle Lancaster

Nursing Research & Professional Development Conference

Background: Innovative nursing practices can reduce hospital sitter usage and costs as a component of a patient-focused safety plan. Sitter use, an evidence-based nursing-driven strategy, effectively decreases falls and injury. This project aimed to improve sitter utilization, documentation, and cost-efficiency by minimizing unneeded use, enhancing policy compliance, and preventing safety incidents. Initially, inpatient managers lacked awareness of direct costs, sitter charges weren't recorded in Epic, and safety concerns for patients and staff existed.

Method: In response to observed inconsistencies in sitter practices and gaps in nursing knowledge, a multidisciplinary workgroup was formed. This group introduced standardized documentation forms, engaged in …


Academic Senate - Agenda, 11/14/2023, Academic Senate Nov 2023

Academic Senate - Agenda, 11/14/2023, Academic Senate

Academic Senate Agendas

No abstract provided.


ความสัมพันธ์ระหว่างการเติบโตทางเศรษฐกิจกับอายุคาดเฉลี่ยในกลุ่มประเทศ Clmv (C: ราชอาณาจักรกัมพูชา L: สาธารณรัฐประชาธิปไตยประชาชนลาว M: สาธารณรัฐแห่งสหภาพเมียนมา V: สาธารณรัฐสังคมนิยมเวียดนาม), มณิภัทร์ ไทรเมฆ Nov 2023

ความสัมพันธ์ระหว่างการเติบโตทางเศรษฐกิจกับอายุคาดเฉลี่ยในกลุ่มประเทศ Clmv (C: ราชอาณาจักรกัมพูชา L: สาธารณรัฐประชาธิปไตยประชาชนลาว M: สาธารณรัฐแห่งสหภาพเมียนมา V: สาธารณรัฐสังคมนิยมเวียดนาม), มณิภัทร์ ไทรเมฆ

Journal of Demography

บทคัดย่อ

การศึกษาครั้งนี้มีวัตถุประสงค์เพื่อศึกษาความสัมพันธ์ระหว่างรายได้ประชาชาติต่อหัวของประชากรกับอายุคาดเฉลี่ยด้วยวิธีการทดสอบความสัมพันธ์เชิงเหตุและผลของ Granger Causality ข้อมูลที่ใช้ในการวิเคราะห์เป็นข้อมูลทุติยภูมิ (Secondary data) ของประเทศในกลุ่ม CLMV (C: ราชอาณาจักรกัมพูชา L: สาธารณรัฐประชาธิปไตยประชาชนลาว M: สาธารณรัฐแห่งสหภาพเมียนมา V: สาธารณรัฐสังคมนิยมเวียดนาม) เป็นประเภทอนุกรมเวลา โดยมีลักษณะเป็นรายปี ตั้งแต่ปี 2000-2018 ผลการศึกษาอายุคาดเฉลี่ยของกลุ่มประเทศ CLMV ทั้งประชากรชายและหญิง พบว่า การทดสอบความนิ่งของข้อมูล ค่าสัมประสิทธิ์ของ ADF test และ KPSS test ณ ระดับนัยสำคัญ 0.05 ที่ระดับต่างๆ และทำการทดสอบ Residual Tests พบว่า ไม่พบปัญหา Autocorrelation และไม่พบปัญหา Heteroscedasticity หลังจากนั้นได้ทำการทดสอบระดับความยากของค่าล่า (lag length) ที่เหมาะสม ผลการทดสอบสมมติฐานเชิงเหตุเชิงผล (Granger Causality) พบว่า การเติบโตทางเศรษฐกิจเป็นต้นเหตุของอายุคาดเฉลี่ยของประชากรชายหญิงของประเทศราชอาณาจักรกัมพูชา และสาธารณรัฐแห่งสหภาพเมียนมา ประชากรหญิงของสาธารณรัฐประชาธิปไตยประชาชนลาว และประชากรชายของสาธารณรัฐสังคมนิยมเวียดนาม แต่ผลการศึกษาที่ผลกลับกัน คือ อายุคาดเฉลี่ยเป็นต้นเหตุของรายได้ประชาชาติต่อหัวของประชากรชายหญิงของสาธารณรัฐประชาธิปไตยประชาชนลาว ประชากรหญิงของสาธารณรัฐแห่งสหภาพเมียนมา และสาธารณรัฐสังคมนิยมเวียดนาม


Targeting Loneliness In Older Adults With Weekly Socialization, Tanja Johnson Nov 2023

Targeting Loneliness In Older Adults With Weekly Socialization, Tanja Johnson

Dissertations

Problem: Loneliness related to social isolation among the older adult population has become an increasing health concern with few interventions available for the general population. Loneliness has been directly associated with depression, poorer physical health outcomes, and overall quality of life.

Methods: The purpose of this study is to evaluate loneliness in the older adult population residing in a senior living community in an urban area in Missouri. Weekly one-on-one socialization, ranging from 45-60 minutes, will be implemented over 6 weeks, with pre and post-intervention screening for loneliness with the 28-item Visit-A-Bit (VAB) screening tool. Approval was received by both …


Effects Of Aging On Post-Exercise Oxygen Consumption: A Preliminary Study, Steven Klepacz Nov 2023

Effects Of Aging On Post-Exercise Oxygen Consumption: A Preliminary Study, Steven Klepacz

Health, Exercise, and Sports Sciences ETDs

Aging and excess post-exercise oxygen consumption (EPOC) is something that has not been adequately studied. Studies looking at EPOC mostly are compiled of young college age individuals. Aging in humans is a topic of much research with still more to be learned. The study in this paper attempts to answer the question of whether age affects EPOC when performing a certain exercise. Preliminary findings based on general age-related research suggest the possibility. This thesis will explore the current research related to age and EPOC, analyze the findings, and discuss additional avenues for future research.


Enforcing Equity, Daiquiri J. Steele Nov 2023

Enforcing Equity, Daiquiri J. Steele

Northwestern University Law Review

Federal administrative agencies that enforce workplace laws have dual responsibilities: (1) to prevent or remedy noncompliance with the underlying workplace law and (2) to prevent or remedy noncompliance with the law’s antiretaliation provisions. Disparities based on race, sex, and their intersection exist with respect to both of these types of employer noncompliance, as female workers and workers of color experience more violations of the substantive provisions and the retaliation provisions of these laws. While effective enforcement is vital to preserving workplace regulation as a whole, there is also an equity component to enforcement. Because workplace law violations disproportionately harm women …


Men’S Sheds: An Outlet For Engaging In Creative Activities, Melinda Heinz Nov 2023

Men’S Sheds: An Outlet For Engaging In Creative Activities, Melinda Heinz

International Journal of Lifelong Learning in Art Education

This research highlights the purpose behind creating an art exhibition featuring work made by Men’s Shed members, many of whom are older adults. Publicly displaying their creative works demonstrates the creative capacities of these older men and counteracts the negative narrative that older adulthood is a time when individuals experience declining abilities. The exhibition also inspires older adults to consider what they can create, experiment with learning new mediums, and provides them an opportunity to connect with others who may share similar interests.


The Ritual Of Therapeutic Artmaking In Long-Term Care, Melinda Heinz Dr., Elissa Wenthe, Alexis Schramel Nov 2023

The Ritual Of Therapeutic Artmaking In Long-Term Care, Melinda Heinz Dr., Elissa Wenthe, Alexis Schramel

International Journal of Lifelong Learning in Art Education

The transition to long-term care settings can be difficult for residents and feelings of loneliness, depression, and anxiety are not uncommon in these environments. However, participating in therapeutic artmaking rituals creates opportunities for residents to process their feelings, experience states of flow and mindfulness, engage with others, and focus on their own psychological growth. In long-term care, the physical needs of residents are often prioritized, but psychosocial needs also require attention. For this project, therapeutic artmaking rituals were created at a long-term care facility in three levels of care over 12 months. Older adults engaged with clay, paint, raw fiber, …


Social Activity Restriction And Psychological Health Among Caregivers Of Older Adults With And Without Dementia, Elliane Irani, Kylie Meyer, Scott Emory Moore, Kedong Ding Nov 2023

Social Activity Restriction And Psychological Health Among Caregivers Of Older Adults With And Without Dementia, Elliane Irani, Kylie Meyer, Scott Emory Moore, Kedong Ding

Faculty Scholarship

Objectives: We examined associations between social activity restriction and psychological distress and well-being for caregivers of older adults with and without dementia, and if the identified associations are different for the two groups. Methods: Using data from the 2017 National Study of Caregiving, we identified caregivers of older adults with (N = 541) and without (N = 1701) dementia. Linear regression models were estimated, adjusting for caregivers’ age, gender, race, education, relationship to care recipient, and self-rated health. Results: Restriction in visiting friends and family and attending religious services were associated with higher distress in dementia caregivers. Restriction in visiting …


Learning After Retirement: The Stories Of Three Chinese Senior Citizens, Yanan Li Nov 2023

Learning After Retirement: The Stories Of Three Chinese Senior Citizens, Yanan Li

USF Tampa Graduate Theses and Dissertations

China, with its vast population, has qualified as an aging society. As a response to this, education and learning have become an important means of improving the quality of life for older people in China. The primary objective of this study is to uncover what stimulates three older Chinese individuals to engage in learning activities by exploring their personal stories. The two research questions guiding the study are: (a) How do three senior Chinese citizens describe their life and learning experiences? and, (b) What factors motivate and influence these three senior Chinese citizens to participate in learning activities? In this …


Centerline, 1992, V1 N1, Fall, Advocate Aurora Health Nov 2023

Centerline, 1992, V1 N1, Fall, Advocate Aurora Health

Historical Documents - Combined

The Park Ridge Center, Chicago, IL: Issue of "CenterLine" an informational newsletter from The Park Ridge Center for the Study of Health, Faith, and Ethics, associated with Lutheran General Hospital. This is the first issue of the publication, and it contains updates on research, publications, staffing, and other news. The research project is on medically assisted suicide.


Centerline, 1994, V3 N1, Fall/Winter, Advocate Aurora Health Nov 2023

Centerline, 1994, V3 N1, Fall/Winter, Advocate Aurora Health

Historical Documents - Combined

The Park Ridge Center, Chicago, IL: Issue of "CenterLine" an informational newsletter from The Park Ridge Center for the Study of Health, Faith, and Ethics, associated with Lutheran General Hospital. This issue contains updates on research, publications, staffing, and other news. The research project is on clinical ethics.


Implementing Health Information Stations At Addiction Recovery Center, Esther Yi, Daryn Hernandez, Maryam Umer, Jasmine Alvarez, Kaitlyn Ward, Riciajoy Padilla Nov 2023

Implementing Health Information Stations At Addiction Recovery Center, Esther Yi, Daryn Hernandez, Maryam Umer, Jasmine Alvarez, Kaitlyn Ward, Riciajoy Padilla

Nursing Leadership in Community Engagement Projects

Implementing Health Information Stations at the Addiction Recovery Center

Six Seattle Pacific University nursing students partnered with an addiction recovery center to address aging healthcare concerns. The recovery center is a non-profit organization that provides a refuge for healing for community members recovering from trauma, homelessness, addiction, and other mental health challenges. Through our weekly meetings with the community, we wanted to address specific barriers such as aging healthcare concerns. We focused on how the low-income aging population posed barriers to aging well.

Background

There has also been a rise in poverty in aging populations (Saldanha, 2023). Though aging influences …


The Covid-19 Crisis And Intergenerational Relations : The Case Of Hong Kong Families With Older Parents Ageing In The Greater Bay Area In Mainland China, Bowen Zhou Nov 2023

The Covid-19 Crisis And Intergenerational Relations : The Case Of Hong Kong Families With Older Parents Ageing In The Greater Bay Area In Mainland China, Bowen Zhou

Lingnan Theses (MPhil & PhD)

The Guangdong-Hong Kong-Macao Greater Bay Area has been developed by the Chinese central government since 2016. Driven by the development of the Greater Bay Area, the well-developed transportation has further provided chances for Hong Kong older people to reside in the mainland GBA cities. The relevant Hong Kong government departments have made a comparison showing that the number of Hong Kong older people (aged 65 and above) who are ageing in the Greater Bay Area of mainland China has increased to around 90,200 in 2019, a 33% increase from 2013. Given the most updated situation, these Hong Kong families with …


Relationship Of Race With Functional And Clinical Outcomes With The Rehab-Hf Multidomain Physical Rehabilitation Intervention For Older Patients With Acute Heart Failure, Olivia N. Gilbert, Robert J. Mentz, Alain G. Bertoni, Dalane W. Kitzman, David J. Whellan, Gordon R. Reeves, Pamela W. Duncan, Michael Benjamin Nelson, Vanessa Blumer, Haiying Chen, Shelby D. Reed, Bharathi Upadhya, Christopher M. O'Connor, Amy M. Pastva Nov 2023

Relationship Of Race With Functional And Clinical Outcomes With The Rehab-Hf Multidomain Physical Rehabilitation Intervention For Older Patients With Acute Heart Failure, Olivia N. Gilbert, Robert J. Mentz, Alain G. Bertoni, Dalane W. Kitzman, David J. Whellan, Gordon R. Reeves, Pamela W. Duncan, Michael Benjamin Nelson, Vanessa Blumer, Haiying Chen, Shelby D. Reed, Bharathi Upadhya, Christopher M. O'Connor, Amy M. Pastva

Department of Medicine Faculty Papers

Background

The REHAB‐HF (Rehabilitation Therapy in Older Acute Heart Failure Patients) randomized trial demonstrated that a 3‐month transitional, tailored, progressive, multidomain physical rehabilitation intervention improves physical function, frailty, depression, and health‐related quality of life among older adults with acute decompensated heart failure. Whether there is differential intervention efficacy by race is unknown.

Methods and Results

In this prespecified analysis, differential intervention effects by race were explored at 3 months for physical function (Short Physical Performance Battery [primary outcome], 6‐Minute Walk Distance), cognition, depression, frailty, health‐related quality of life (Kansas City Cardiomyopathy Questionnaire, EuroQoL 5‐Dimension‐5‐Level Questionnaire) and at 6 months for …


The Park Ridge Center Bulletin, 1998, N6, October/November, Advocate Aurora Health Nov 2023

The Park Ridge Center Bulletin, 1998, N6, October/November, Advocate Aurora Health

Historical Documents - Combined

The Park Ridge Center, Park Ridge, IL: Issue of "The Park Ridge Center Bulletin", a bi-monthly publication from The Park Ridge Center - An Institute for the Study of Health, Faith, and Ethics, associated with Lutheran General Hospital. This issue has feature articles on aging, elder care, and nursing homes.


The Effect Of Obesity On Comorbidities: A Benchmark Study, Kaley Nolen Nov 2023

The Effect Of Obesity On Comorbidities: A Benchmark Study, Kaley Nolen

MSN Capstone Projects

Obesity is distinguished by a body mass index (BMI) greater than 30. Tremmel et al. (2017) reports obese individuals are at a greater risk for developing cardiovascular disease, diabetes, and cancer. In 2014, approximately 641 million adults were classified as obese (Zhang et al., 2018). This epidemic has drastically worsened over the last two decades resulting in obesity ranking as the fifth most common cause of death globally (Safaei et al., 2021). Okunogbe et al. (2021) states, slowing the incidence rate of obesity by 5% will save approximately $3.3 billion annually between 2020-2060. The pathophysiology and cause of obesity is …


Age & Dementia Friendly Plymouth: A Community Needs Assessment, Caitlin E. Coyle, Beth Rouleau, Ceara Somerville Nov 2023

Age & Dementia Friendly Plymouth: A Community Needs Assessment, Caitlin E. Coyle, Beth Rouleau, Ceara Somerville

Center for Social and Demographic Research on Aging Publications

This report describes research undertaken by the Center for Social & Demographic Research on Aging (CSDRA) within the Gerontology Institute at the University of Massachusetts Boston, on behalf of the Town of Plymouth. The goals of this project were to investigate the needs, interests, preferences, and opinions of Plymouth’s residents age 55 or older in support of the Council on Aging’s (COA’s) objective to identify and serve the needs of all Plymouth citizens 55 and older. The contents of this report are meant to inform the Town of Plymouth, the Plymouth COA, the Center for Active Living, and organizations that …


Multimodal Analysis Of Secondary Cerebellar Alterations After Pediatric Traumatic Brain Injury, Finian Keleher, Hannah M Lindsey, Rebecca Kerestes, Houshang Amiri, Robert F Asarnow, Talin Babikian, Brenda Bartnik-Olson, Erin D Bigler, Karen Caeyenberghs, Carrie Esopenko, Linda Ewing-Cobbs, Christopher C Giza, Naomi J Goodrich-Hunsaker, Cooper B Hodges, Kristen R Hoskinson, Andrei Irimia, Marsh Königs, Jeffrey E Max, Mary R Newsome, Alexander Olsen, Nicholas P Ryan, Adam T Schmidt, Dan J Stein, Stacy J Suskauer, Ashley L Ware, Anne L Wheeler, Brandon A Zielinski, Paul M Thompson, Ian H Harding, David F Tate, Elisabeth A Wilde, Emily L Dennis Nov 2023

Multimodal Analysis Of Secondary Cerebellar Alterations After Pediatric Traumatic Brain Injury, Finian Keleher, Hannah M Lindsey, Rebecca Kerestes, Houshang Amiri, Robert F Asarnow, Talin Babikian, Brenda Bartnik-Olson, Erin D Bigler, Karen Caeyenberghs, Carrie Esopenko, Linda Ewing-Cobbs, Christopher C Giza, Naomi J Goodrich-Hunsaker, Cooper B Hodges, Kristen R Hoskinson, Andrei Irimia, Marsh Königs, Jeffrey E Max, Mary R Newsome, Alexander Olsen, Nicholas P Ryan, Adam T Schmidt, Dan J Stein, Stacy J Suskauer, Ashley L Ware, Anne L Wheeler, Brandon A Zielinski, Paul M Thompson, Ian H Harding, David F Tate, Elisabeth A Wilde, Emily L Dennis

Faculty, Staff and Student Publications

Importance: Traumatic brain injury (TBI) is known to cause widespread neural disruption in the cerebrum. However, less is known about the association of TBI with cerebellar structure and how such changes may alter executive functioning.

Objective: To investigate alterations in subregional cerebellum volume and cerebral white matter microstructure after pediatric TBI and examine subsequent changes in executive function.

Design, setting, and participants: This retrospective cohort study combined 12 data sets (collected between 2006 and 2020) from 9 sites in the Enhancing Neuroimaging Genetics Through Meta-Analysis Consortium Pediatric TBI working group in a mega-analysis of cerebellar structure. Participants with TBI or …


Economic Equity And People With Disabilities: Development And Characterization Of A Novel Index, Bhavneet Walia, Katherine Mcdonald, Joy Hammel, Lex Frieden, Michael Morris, Barry Whaley, Vinh Nguyen Nov 2023

Economic Equity And People With Disabilities: Development And Characterization Of A Novel Index, Bhavneet Walia, Katherine Mcdonald, Joy Hammel, Lex Frieden, Michael Morris, Barry Whaley, Vinh Nguyen

Faculty, Staff and Student Publications

Here we develop two new social indices: The ADA PARC Absolute Economic Opportunity Index and the ADA PARC Relative Economic Opportunity Index. These indices allow us novel examinations of economic equity between people with and without disabilities within a U.S. State and between people with disabilities in different states using aggregations of multiple component economic indicators. These represent the first efforts to offer U.S. indices of this focus, an important development given the distinct economic needs of people with disabilities and the value in accounting for distinct national policies. The indices rely on U.S. Census and other data on economic …


Recent Developments In Frailty Identification, Management, Risk Factors And Prevention: A Narrative Review Of Leading Journals In Geriatrics And Gerontology, Elsa Dent, Peter Hanlon, Marc Sim, Juulia Jylhävä, Zuyun Liu, Davide L. Vetrano, Erwin Stolz, Mario U. Pérez-Zepeda, Daniel R. Crabtree, Caroline Nicholson, Jenny Job, Rachel C. Ambagtsheer, Paul R. Ward, Sandra M. Shi, Quan Huynh, Emiel O. Hoogendijk Nov 2023

Recent Developments In Frailty Identification, Management, Risk Factors And Prevention: A Narrative Review Of Leading Journals In Geriatrics And Gerontology, Elsa Dent, Peter Hanlon, Marc Sim, Juulia Jylhävä, Zuyun Liu, Davide L. Vetrano, Erwin Stolz, Mario U. Pérez-Zepeda, Daniel R. Crabtree, Caroline Nicholson, Jenny Job, Rachel C. Ambagtsheer, Paul R. Ward, Sandra M. Shi, Quan Huynh, Emiel O. Hoogendijk

Research outputs 2022 to 2026

Frailty is an age-related clinical condition characterised by an increased susceptibility to stressors and an elevated risk of adverse outcomes such as mortality. In the light of global population ageing, the prevalence of frailty is expected to soar in coming decades. This narrative review provides critical insights into recent developments and emerging practices in frailty research regarding identification, management, risk factors, and prevention. We searched journals in the top two quartiles of geriatrics and gerontology (from Clarivate Journal Citation Reports) for articles published between 01 January 2018 and 20 December 2022. Several recent developments were identified, including new biomarkers and …


Psychological Safety And Conflict Management Among Nurse Practitioners In Interprofessional Teams, Scott Tyler Faust Nov 2023

Psychological Safety And Conflict Management Among Nurse Practitioners In Interprofessional Teams, Scott Tyler Faust

Electronic Theses and Dissertations

This quantitative correlational study explored the relationships between perceived psychological safety, conflict management styles, and perceived conflict management success among nurse practitioners (NPs) operating in interprofessional acute or critical care teams in the United States. Despite existing literature on conflict management and psychological safety, there is a noticeable gap concerning the interplay of these factors, specifically among NPs. A multi-item survey was developed from validated measures to assess psychological safety, conflict management success, and conflict management style. The final sample included 944 NPs. The findings revealed a statistically significant difference in the scores of perceived psychological safety, depending on the …


Gelation Of Cytoplasmic Expanded Cag Rna Repeats Suppresses Global Protein Synthesis, Yuyin Pan, J Lu, Xinran Feng, S Lu, Y Yang, G Yang, Shudan Tan, Liang Wang, Pilong Li, Shouqing Luo, B Lu Nov 2023

Gelation Of Cytoplasmic Expanded Cag Rna Repeats Suppresses Global Protein Synthesis, Yuyin Pan, J Lu, Xinran Feng, S Lu, Y Yang, G Yang, Shudan Tan, Liang Wang, Pilong Li, Shouqing Luo, B Lu

Peninsula Medical School

RNA molecules with the expanded CAG repeat (eCAGr) may undergo sol–gel phase transitions, but the functional impact of RNA gelation is completely unknown. Here, we demonstrate that the eCAGr RNA may form cytoplasmic gel-like foci that are rapidly degraded by lysosomes. These RNA foci may significantly reduce the global protein synthesis rate, possibly by sequestering the translation elongation factor eEF2. Disrupting the eCAGr RNA gelation restored the global protein synthesis rate, whereas enhanced gelation exacerbated this phenotype. eEF2 puncta were significantly enhanced in brain slices from a knock-in mouse model and from patients with Huntington’s disease, which is a CAG …


Using The Five Ps: Conceptualizing Covid-19-Related Mental Health Concerns, Christine D. Gonzales-Wong, Scott Peters Oct 2023

Using The Five Ps: Conceptualizing Covid-19-Related Mental Health Concerns, Christine D. Gonzales-Wong, Scott Peters

Teaching and Supervision in Counseling

The COVID-19 pandemic has resulted in rising mental health concerns. As individuals experience loneliness, anxiety, and depression related to the pandemic, counselors-in-training navigate their treatment of clients while also living through the pandemic and its polarization. The authors present the Five Ps, a case conceptualization model that supervisors can use to help beginning counselors consider the history and context of the presenting concerns of clients, in addition to utilizing clients’ strengths in treatment. The authors provide a case illustration using the Five Ps in a supervision setting and discuss implications for supervision and future research.


Exploring The Dynamic Reading Of Environment Towards A Multidimensional Legibility, Putri Mahsa Gantari, Ferro Yudistira Oct 2023

Exploring The Dynamic Reading Of Environment Towards A Multidimensional Legibility, Putri Mahsa Gantari, Ferro Yudistira

ARSNET

This study investigates the understanding of legibility, defined as the coherency of built environment features. Legibility enables production of mental image that helps individuals with their spatial navigation. The current discussion positions legibility as an objective aspect in the process of making sense of the environment. The study argues that such a process has dynamics that reflect individuals' subjectivity, therefore further study is important to reconcile the objective and subjective reading of legibility. This research qualitatively investigates legibility using a case study of an indoor environment of a shopping mall in East Jakarta. The analysis was conducted based on the …


A Duel Role: Nurses As Family Caregivers, Megan Thomas Hebdon, Vyshnavi Pottepalli, Dona Ravandi, Zainah Siddiqi, Saneeva George, Aashi Vishnoi, Carolyn Phillips, Jung Kwak Oct 2023

A Duel Role: Nurses As Family Caregivers, Megan Thomas Hebdon, Vyshnavi Pottepalli, Dona Ravandi, Zainah Siddiqi, Saneeva George, Aashi Vishnoi, Carolyn Phillips, Jung Kwak

Sigma Foundation for Nursing Research Grant Reports

The purpose of this study is to understand the emotional and financial wellbeing for nurses who balance the dual caregiving role of "nurse" and "family caregiver," (referred as dual role caregiver henceforth) and develop a stakeholder-informed dual role caregiver support intervention prototype.


Older Women As Active Online Agents: Diversifying Cultural Conceptions Of “Grannies” Through Social Media, Hanna Varjakoski Oct 2023

Older Women As Active Online Agents: Diversifying Cultural Conceptions Of “Grannies” Through Social Media, Hanna Varjakoski

Journal of International Women's Studies

With the advent of social media, the media environment has become more participatory for its users, making it possible for older adults to produce content for social media and be agential in online spaces. This article observes a group of older women known as Activist Grannies (Aktivistimummot in Finnish) and 60+ Finnish women bloggers who identify as “grannies” to discover what kind of agency social media potentially enables for older women. In addition, this article explores the cultural knowledge produced by older women’s self-representations as activist grannies and “granny bloggers.” I demonstrate that social media offers a space to …


Research Progress On Constituent Structure And Extraction Technique Of The Polysaccharide From Agaricus Blazei, Cui Guomei, Liu Lina, Tian Guangrui, Li Shunfeng, Xu Fangfang, Wang Anjian Oct 2023

Research Progress On Constituent Structure And Extraction Technique Of The Polysaccharide From Agaricus Blazei, Cui Guomei, Liu Lina, Tian Guangrui, Li Shunfeng, Xu Fangfang, Wang Anjian

Food and Machinery

The composition, structure and functional properties of Agaricus blazei polysaccharide were summarized. The extraction techniques of polysaccharides and the features of different extraction methods were enumerated and compared. The problems in the research of A. blazei was discussed, such as unsystematic basic research, immature technological conditions, imperfect equipment and facilities, and low degree of specificity in seeds. In the end,the research direction of A. blazei polysaccharide was prospected.