Digital Commons Network^™

Dietary Behaviours During Covid-19 Among Households At Risk For Food Insecurity, Christine Markham

Faculty, Staff and Student Publications

The objective of the present study was to examine associations between variables of COVID-19-related concerns and changes in fruit and vegetable (FV) consumption among a sample of participants from the Brighter Bites program at risk for food insecurity. Cross-sectional data were collected during April-June 2020 using a rapid-response survey to understand social needs, COVID-19-related concerns and diet-related behaviours among families with children participating in Brighter Bites (

Validation Of A Process For Shared Decision-Making In Pediatrics, Douglas J Opel, Holly Hoa Vo, Nicolas Dundas, Heather Spielvogle, Amanda Mercer, Benjamin S Wilfond, Jonna Clark, Carrie L Heike, Elliott M Weiss, Mersine A Bryan, Seema K Shah, Carolyn A Mccarty, Jeffrey D Robinson, Jennifer Blumenthal-Barby, Jon Tilburt

Center for Medical Ethics and Health Policy Staff Publications

OBJECTIVE: We sought to confirm, refute, or modify a 4-step process for implementing shared decision-making (SDM) in pediatrics that involves determining 1) if the decision includes >1 medically reasonable option; 2) if one option has a favorable medical benefit-burden ratio compared to other options; and 3) parents' preferences regarding the options; then 4) calibrating the SDM approach based on other relevant decision characteristics.

METHODS: We videotaped a purposive sample of pediatric inpatient and outpatient encounters at a single US children's hospital. Clinicians from 7 clinical services (craniofacial, neonatology, oncology, pulmonary, pediatric intensive care, hospital medicine, and sports medicine) were eligible. …

The Potential Of Ketamine For Posttraumatic Stress Disorder: A Review Of Clinical Evidence, Anya Ragnhildstveit, Jeremy Roscoe, Lisa C Bass, Christopher L Averill, Chadi G Abdallah, Lynnette A Averill

Staff and Researcher Publications

Posttraumatic stress disorder (PTSD) is a devastating condition, for which there are few pharmacological agents, often with a delayed onset of action and poor efficacy. Trauma-focused psychotherapies are further limited by few trained providers and low patient engagement. This frequently results in disease chronicity as well as psychiatric and medical comorbidity, with considerable negative impact on quality of life. As such, off-label interventions are commonly used for PTSD, particularly in chronic refractory cases. Ketamine, an N-methyl-D-aspartate (NDMA) receptor antagonist, has recently been indicated for major depression, exhibiting rapid and robust antidepressant effects. It also shows transdiagnostic potential for an …

Meta-Analysis Of The Effectiveness Of Project-Based Learning Approach On Academic Achievement In Higher Education Worldwide, Ziyu Meng

Doctoral Dissertations

This research study conducted a meta-analysis to integrate the studies that investigated the effectiveness of project-based learning on academic achievement based on a worldwide higher-education population. The researcher explored the variables that previous meta-analysis studies used to evaluate academic achievements, such as student grade point average (GPA), course grades, and test scores, to explore the use of these variables in project-based learning. There were 17 studies in total included in the meta-analysis evaluating the effect size of academic achievement, which was influenced in moderator variable by subject-matter areas, school location, hours of instruction, technology support, and group size. The researcher …

Social Protection And Foundational Cognitive Skills During Adolescence: Evidence From A Large Public Works Program, Sirunya Silapunt

Faculty, Staff and Student Publications

INTRODUCTION: Reddit, a popular social media website, has numerous forums where users may discuss healthcare-related topics and request diagnostic and treatment advice for dermatologic conditions. We sought to analyze and grade user-submitted requests for dermatologic advice and their top responses on Reddit.

METHODS: User-submitted posts requesting diagnostic advice and their respective responses on two popular Reddit forums, SkinCareAddiction (ScA) and DermatologyQuestions (DQ), were reviewed by three board-certified dermatologists using a grading rubric designed for this study.

RESULTS: 300 posts and comments were reviewed. Diagnoses among all graders matched in 52.3% of posts with a mean grader confidence score of 4/5 …

Population-Based Linked Longitudinal Surveillance Of Pregnant People And Their Infants: A Critical Resource For Emerging, Re-Emerging, And Persistent Threats, Amanda Akosa

Faculty, Staff and Student Publications

Public health emergencies, from Zika to COVID-19, have underscored the importance of addressing the needs of pregnant people and their infants. Recent events have underlined the critical role of mother-infant-linked longitudinal surveillance to characterize and assess the impacts of emerging, re-emerging, and persistent threats, including infectious diseases, on these populations. In partnership with state, local, and territorial health departments, CDC's National Center on Birth Defects and Developmental Disabilities activated the Surveillance for Emerging Threats to Mothers and Babies Network (SET-NET) to capture information about pregnant people with laboratory-confirmed infection with SARS-CoV-2 (the virus that causes COVID-19) and their infants. SET-NET …

Incidental Detection Of A Rare Pediatric High-Grade Fibrosarcoma In A Post-Traumatic Setting: The Conundrum Of Intra-Abdominal Hematoma Versus Neoplasia, Olanrewaju A Ogunleye

Faculty, Staff and Student Publications

Infantile fibrosarcoma (IF) is a rare malignant fibroblastic tumor that affects infants and young children, occurring most commonly in the extremities. Here, we present a 14-year-old patient with an abdominal mass incidentally detected after a blunt injury to the abdomen. The initial trauma protocol CT revealed a high attenuation mesenteric lesion in the left central abdomen suggestive of mesenteric hematoma. However, the possibility of a solid neoplastic mass lesion could not be excluded. Further evaluation with dynamic contrast-enhanced serial MRI showed a progressive enhancing mass and excluded a hyperacute hematoma with active bleeding. The mass was resected, and histopathological examination …

Disruption Of Specific White Matter Tracts Is Associated With Neurogenic Lower Urinary Tract Dysfunction In Women With Multiple Sclerosis, Khader M Hasan, Betsy Salazar, Rose Khavari

Faculty, Staff and Student Publications

OBJECTIVE: To identify specific white matter tracts (WMTs) whose disruption is associated with the severity of neurogenic lower urinary tract dysfunction (NLUTD) in two independent cohorts of women with multiple sclerosis (MS) and NLUTD.

METHODS: Cohort 1 consisted of twenty-eight women with MS and NLUTD. The validation cohort consisted of 10 women with MS and NLUTD. Eleven healthy women served as controls. Participants of both MS cohorts had the same inclusion and exclusion criteria. Both MS cohorts and the healthy controls underwent the same clinical assessment and functional MRI (fMRI) protocol, except that the validation MS cohort underwent 7-Tesla fMRI …

Timing Of Invasive Mechanical Ventilation And Death In Critically Ill Adults With Covid-19: A Multicenter Cohort Study, Jonathan D Casey, Shahzad Shaefi, Krystal Hunter, David E Leaf

Faculty, Staff and Student Publications

PURPOSE: To investigate if the timing of initiation of invasive mechanical ventilation (IMV) for critically ill patients with COVID-19 is associated with mortality.

MATERIALS AND METHODS: The data for this study were derived from a multicenter cohort study of critically ill adults with COVID-19 admitted to ICUs at 68 hospitals across the US from March 1 to July 1, 2020. We examined the association between early (ICU days 1-2) versus late (ICU days 3-7) initiation of IMV and time-to-death. Patients were followed until the first of hospital discharge, death, or 90 days. We adjusted for confounding using a multivariable Cox …

Risk Of Depression In A Suburban Primary Care Setting Before And During The Covid-19 Pandemic

Faculty, Staff and Student Publications

INTRODUCTION: Major depression is a common disorder affecting millions of adults each year. Many population-based surveys showed an increase in the number people with symptoms of depression at the onset of the COVID-19 pandemic. Our aim was to determine and compare the prevalence of depression risk in a primary care setting before and during the COVID-19 pandemic.

METHODS: We conducted a cross-sectional study based on retrospective review of medical records from a large suburban primary care clinic. Records of adults 18 years and older, seen between January 1, 2019 and December 31, 2020 and who had also been screened for …

Development Of Competency-Based Online Genomic Medicine Training (Cogent), Philip E Empey, Siddharth K Prakash, Laura B Ramsey, Robb Rowley, Carolyn R Rohrer Vitek, Todd C Skaar, Julia Wynn, Teri A Manolio

Faculty, Staff and Student Publications

The fields of genetics and genomics have greatly expanded across medicine through the development of new technologies that have revealed genetic contributions to a wide array of traits and diseases. Thus, the development of widely available educational resources for all healthcare providers is essential to ensure the timely and appropriate utilization of genetics and genomics patient care. In 2020, the National Human Genome Research Institute released a call for new proposals to develop accessible, sustainable online education for health providers. This paper describes the efforts of the six teams awarded to reach the goal of providing genetic and genomic training …

Health Disparities In Turner Syndrome: Uthealth Turner Syndrome Research Registry

Faculty, Staff and Student Publications

AIM: Turner Syndrome (TS) is caused by partial or complete absence of the second sex chromosome in a phenotypic female. TS is associated with recognizable congenital anomalies and chronic health conditions. The principal objective of this study was to evaluate the health-related knowledge and insight of participants.

METHODS: In 2015, we founded the UTHealth Turner Syndrome Research Registry for longitudinal follow-up of individuals with TS. Study participants were recruited from UTHealth Houston clinics and the Turner Syndrome Society of the United States. Participants completed a questionnaire about demographics, karyotype, congenital anomalies, health history, frequency of contact with care providers, and …

Volatile Anesthetic And Outcome In Acute Trauma Care: Planned Secondary Analysis Of The Proppr Study, Charles E Wade, Olga Y Kaslow, Jean-Francois Pittet, Evan P Pivalizza

Faculty, Staff and Student Publications

BACKGROUND: This retrospective analysis of prospectively collected data from the PROPPR study describes volatile anesthetic use in severely injured trauma patients undergoing anesthesia.

METHODS: After exclusions, 402 subjects were reviewed of the original 680, and 292 had complete data available for analysis. Anesthesia was not protocolized, so analysis was of contemporary practice.

RESULTS: The small group who received no volatile anesthetic (n = 25) had greater injury burden (Glasgow Coma Scale

CONCLUSION: In this acutely injured trauma population, choice of volatile anesthetic did not appear to influence short-term mortality and morbidity. Subjects who received no volatile were more severely injured …

Sex-Biased Autophagy As A Potential Mechanism Mediating Sex Differences In Ischemic Stroke Outcome

Faculty, Staff and Student Publications

Stroke is the second leading cause of death and a major cause of disability worldwide, and biological sex is an important determining factor in stroke incidence and pathology. From childhood through adulthood, men have a higher incidence of stroke compared with women. Abundant research has confirmed the beneficial effects of estrogen in experimental ischemic stroke but genetic factors such as the X-chromosome complement can also play an important role in determining sex differences in stroke. Autophagy is a self-degrading cellular process orchestrated by multiple core proteins, which leads to the engulfment of cytoplasmic material and degradation of cargo after autophagy …

Chatgpt: Is It Good For Our Glaucoma Patients?, Sahej Sidhu

Faculty, Staff and Student Publications

Purpose: Our study investigates ChatGPT and its ability to communicate with glaucoma patients.

Methods: We inputted eight glaucoma-related questions/topics found on the American Academy of Ophthalmology (AAO)'s website into ChatGPT. We used the Flesch-Kincaid test, Gunning Fog Index, SMOG Index, and Dale-Chall readability formula to evaluate the comprehensibility of its responses for patients. ChatGPT's answers were compared with those found on the AAO's website.

Results: ChatGPT's responses required reading comprehension of a higher grade level (average = grade 12.5 ± 1.6) than that of the text on the AAO's website (average = 9.4 grade ± 3.5), (0.0384). For the eight …

Developing The Lex Mercatoria, Tiong Min Yeo

Research Collection Yong Pung How School Of Law

The historical lex mercatoria, or law merchant, is said to have emerged from the customary practices of ancient and medieval seamen and traders who found themselves in need of a common set of rules to govern mercantile trade; rules which would be broadly applicable (and acceptable) to trading parties regardless of their places of origin. To the extent that such a body of legal rules did in fact exist, its significance derived from two main features: (1) its independence (since it was not promulgated by any one decision-maker or legislator, but was drawn from the established practice of the merchant …

The Political Ecology Of Death: Chinese Religion And The Affective Tensions Of Secularised Burial Rituals In Singapore, Quan Gao, Orlando Woods, Lily Kong

Research Collection School of Social Sciences

This paper explores the political ecology of death and the affective tensions of secularised burial rituals in Singapore. Although scholars have recently acknowledged the roles of biopower and affect in shaping environmental politics, religion and death as socio-affective forces have not been substantively engaged with by political ecologists. We argue that death is inherently both a spiritual and ecological phenomenon, as it exposes not only the spiritual geographies that structure how people see the natural world, but also the affective tensions and struggles over what counts as a “proper” form of burial in relation to religion and nature. First, we …

Covid-19 And Investor-State Disputes: Have The Stars Aligned For Mediation?, Mark Mclaughlin

Research Collection Yong Pung How School Of Law

In response to the global pandemic, governments have compelled the production of ventilators, limited service provision to “essential” goods, suspended bills for electricity, gas and water, and implemented price and export controls. Regulatory measures have consciously inhibited economic activity and disrupted investment interests. Inevitably, foreign investors are among those adversely affected by measures directed towards the containment of COVID-19. Since the first bilateral investment treaty (“BIT”) was concluded in 1959, international investment agreements (“IIAs”) have served as derogations to the general international law principle that States have absolute discretion to restrict and regulate foreign investors within their territories.2 As such, …

Speculations On Force And Form: Resisting The Neurotypical In The Neoliberal University, Helen Bowstead

School of Law, Humanities and Social Sciences Theses

Can reframing a thesis in terms of what it can do rather than what it is generate a joyful-artful engagement with the PhD process and engender a more response-able relationship with the world? In this tentative exemplification of the speculative potential of force and form, the very act of writing emerges as a powerful antidote to constraints of the neoliberal university. Exploring writing as immanent doing, Erin Manning’s philosophical projects of research-creation, artfulness and thought in motion find expression through the ordinary, the everyday and the mundane. By refusing to engage in the dis-abling constraints prescribed by institutional expectations of …

I Am A Camera, Subverted: Reflexivity, Sexuality, And Filming Styles In Bob Fosse’S 'Sweet Charity' (1969), 'Cabaret' (1972), And 'All That Jazz' (1979), Steven Downes

School of Law, Humanities and Social Sciences Theses

The musical films of Bob Fosse, 'Sweet Charity' (1969), 'Cabaret' (1972), and 'All That Jazz' (1979) offer a radical alternative to the ‘arcadian’ musical format with edgier and darker themes as a response to the rapidly developing socio-politico climate and the sexual revolution. However, although 'Cabaret' remains well documented, his other musical films 'Sweet Charity' and 'All That Jazz', remain primarily neglected in academia, which I will rectify. Moreover, while many prolific writers and scholars, including Laura Mulvey and Rick Altman, have previously analysed the movie and film musical from a heteronormative male gaze perspective, this is at odds with …

Alterity In Central And Eastern European Illustrations For The Lord Of The Rings 1981-1993, Joel Merriner

School of Law, Humanities and Social Sciences Theses

The 2001-2003 cinematic release of Peter Jackson’s movie adaptation of J.R.R. Tolkien’s The Lord of the Rings heralded a period of widespread pictorial homogenisation in Tolkien visual culture. Propelled by the conceptual design of veteran “Western” Tolkien artists Alan Lee and John Howe, Jackson’s vision of Middle-earth became the hegemonic model by which other depictions are measured. Consequently, the potential for undertaking a scholarly examination of an alternative, specifically non-Western Tolkien vision (with all the implications for visual difference and/or commonality this might involve), has been largely ignored. This dissertation, however, seeks to foster a deeper understanding of the possibility …

Evidence-Based Guidelines For Intrapartum Maternal Hydration Assessment And Management: A Scoping Review, Lauren Kearney, Alison Craswell, Nellie Dick, Debbie Massey, Rachael Nugent

Research outputs 2022 to 2026

Problem: Inconsistent practice relating to intrapartum hydration assessment and management is reported, and potential harm exists for laboring women and birthing persons. Background: Labor and birth are physically demanding, and adequate nutrition and hydration are essential for labor progress. A lack of clear consensus on intrapartum hydration assessment and management during labor and birth currently exists. In addition, there is an inconsistent approach to managing hydration, often including a mixture of intravenous and oral fluids that are poorly monitored. Aim: The aim of this scoping review was to identify and collate evidence-based guidelines for intrapartum hydration assessment and management of …

International Café: A Collaborative Approach To International Student Wellbeing And Support, Yohann Devezy, Braden Hill, Liz Beresford, Rose Williams, Shirley Farr, Em Readman, Clair Mermejo

Research outputs 2022 to 2026

Prior to 2020, ongoing discourse in the higher education sector underscored the increasingly complex mental health and wellbeing challenges faced by students. The “post-COVID-19” period witnessed a resurgence of international students arriving in Western Australia. Emerging cost of living pressures, accommodation shortages, and changing visa work hours have amplified the distinct challenges international students encounter, prompting renewed discussions surrounding a need for effective support interventions. Drawing inspiration from successful initiatives at Edith Cowan University, Murdoch University introduced the Murdoch International Café—a program focused on providing distinct spaces of support for international students. This supportive environment enables social connection, effective information …

Reading Group As Method For Feminist Environmental Humanities, James Gardiner, Hayley Singer, Jennifer Hamilton, Astrida Neimanis, Mindy Blaise

Research outputs 2022 to 2026

This article argues that reading groups are a collective field building and research method in Feminist Environmental Humanities, an interdisciplinary scholarly area at the intersections of feminist social justice and environmental concerns. We begin by historicising three Australian Feminist Environmental reading groups (COMPOSTING Feminisms, Eco Feminist Fridays, The Ediths) within a longer feminist tradition, then demonstrate how they respond to declining research funding in the neoliberal university and accelerating ecological crisis. Drawing on survey data, we first thematically code and analyse the results to categorise the groups’ functions and impacts. Departing from more traditional data analysis, we then develop a …

Tourism Experiences Reduce The Risk Of Cognitive Impairment In The Chinese Older Adult: A Prospective Cohort Study, Qian Li, Zheng Guo, Fangli Hu, Mengfei Xiao, Qiang Zhang, Jun Wen, Tianyu Ying, Danni Zheng, Youxin Wang, Song Yang, Haifeng Hou

Research outputs 2022 to 2026

Background: Given the etiological complexity of cognitive impairment, no effective cure currently exists for precise treatment of dementia. Although scholars have noted tourism’s potential role in managing cognitive impairment and mild dementia, more robust empirical investigation is needed in this area. This study aimed to examine the associations between tourism and cognitive impairment and dementia in older Chinese adults. Method: From a nationwide community-based cohort, 6,717 individuals aged ≥ 60 were recruited from 2011 to 2014, of whom 669 (9.96%) had had at least one tourism experience in the 2 years prior to enrollment. All the participants were then prospectively …

A Current Affair: Worker Perceptions Of Noise Exposure And Occupational Hearing Loss In Australian Coal Mines, Adelle Liebenberg, Jacques Oosthuizen, Sue Reed

Research outputs 2022 to 2026

Background: The objective of the online survey was to determine worker attitudes towards, perceptions on hearing loss, and management of workplace noise; and to identify barriers within current strategies that prevent effective management of hearing health in Australian mines. Design: This cross-sectional study utilized a modified survey design, initially designed for use by Safe Work Australia for a broader study published in 2010. Study Sample: The survey questionnaire was made available online to volunteer participants, recruited with the assistance of State and National Health and Safety, and mining organizations. Volunteer participants were required to be proficient in English, be employed …

Elevated Plasma Sclerostin Is Associated With High Brain Amyloid-B Load In Cognitively Normal Older Adults, Jun Yuan, Steve Pedrini, Rohith Thota, James Doecke, Pratishtha Chatterjee, Hamid R. Sohrabi, Charlotte E. Teunissen, Inge M. W. Verberk, Erik Stoops, Hugo Vanderstichele, Bruno P. Meloni, Christopher Mitchell, Stephanie Rainey-Smith, Kathryn Goozee, Andrew C. P. Tai, Nicholas Ashton, Henrik Zetterberg, Kaj Blennow, Junjie Gao, Delin Liu, Frank Mastaglia, Charles Inderjeeth, Minghao Zheng, Ralph Martins

Research outputs 2022 to 2026

Osteoporosis and Alzheimer’s disease (AD) mainly affect older individuals, and the possibility of an underlying link contributing to their shared epidemiological features has rarely been investigated. In the current study, we investigated the association between levels of plasma sclerostin (SOST), a protein primarily produced by bone, and brain amyloid-beta (A ) load, a pathological hallmark of AD. The study enrolled participants meeting a set of screening inclusion and exclusion criteria and were stratified into A − (n = 65) and A + (n = 35) according to their brain A load assessed using A -PET (positron emission tomography) imaging. Plasma …

Lesbian, Anorexic, Disabled, And Big: Other Ways Of Being A Female Physical Education Teacher, Gustavo González-Calvo, Valeria Varea

Research outputs 2022 to 2026

Research has shown that Physical Education (PE) is a white, male, and able body-dominated profession, particularly in Spain. When some female pre-service PE teachers, who had a difficult relationship with their bodies and sports abilities, enrol in such a degree, some of these problematic relations come to light. Participants for this study were four female pre-service teachers who self-identified as lesbian, anorexic, visually impaired, and big respectively. Data were collected through participant-produced texts, graphical representations, and interviews. The authors then reconstructed the participants’ stories which are presented in the form of narratives. The conceptual tool of embodying norm-criticality helped us …

Exploring Perceptions Of Travel-Eligible Individuals With Dementia And Hotel Operators, Jun Wen, Danni Zheng, Yangyang Jiang, Haifeng Hou, Ian Phau, Wei Wang

Research outputs 2022 to 2026

Although people with dementia have leisure travel needs, no scholars appear to have empirically explored how to meet this group’s needs as hotel guests. To bridge this research gap in tourism literature, the current study employed in-depth interviews to collect first-hand data from 15 travel-eligible tourists with early-stage dementia and 15 senior luxury hotel managers in China. Specifically, six key themes were extracted from Chinese hotel guests with dementia. Hotel managers’ commentary on meeting travel-eligible tourists with dementia’ needs during leisure travel led to three themes. Innovatively, this study further sheds light on possible contributions the tourism and hospitality industry …

Palliative And End-Of-Life Care Access For Immigrants Living In High-Income Countries: A Scoping Review, Gertrude G. Phiri, Joyce Muge-Sugutt, Davina Porock

Research outputs 2022 to 2026

This scoping review aimed to explore what is known about palliative and End-of-Life (EOL) care access by immigrants with culturally and linguistically diverse (CALD) background living in high-income Organization for Economic Co-operation and Development (OECD) countries. CaLD immigrants have low utilization of palliative care services with patients’ family members taking up the role of caring, leading to immigrants not fully benefiting from the specialized services that are offered to alleviate suffering and promote quality of life. While there is some research in this area mainly in Europe, it cannot be said about all high-income OECD countries. Achieving person-centered care in …