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Full-Text Articles in Entire DC Network
The President Of The Senate, The Original Public Meaning Of The Twelfth Amendment, And The Electoral Count Reform Act, Derek T. Muller
The President Of The Senate, The Original Public Meaning Of The Twelfth Amendment, And The Electoral Count Reform Act, Derek T. Muller
Case Western Reserve Law Review
No abstract provided.
Measurements Of The Binding Energies Of Ions On Plastic Surfaces In Liquid Nitrogen, Ashok Timsina
Measurements Of The Binding Energies Of Ions On Plastic Surfaces In Liquid Nitrogen, Ashok Timsina
Theses and Dissertations--Physics and Astronomy
To improve the present limit of the neutron electric dipole moment (nEDM) from 1.8*10-26 e. cm to ~ 3*10-28 e. cm, the nEDM@SNS experiment plans to increase neutron density by storing ultracold neutrons in superfluid helium-4. In this experiment, the central part of the apparatus consists of two deuterated tetraphenyl butadiene (dTPB) coated poly(methyl methacrylate) (PMMA) cells, which are sandwiched between grounded and high-voltage electrodes. To achieve such precision, the externally applied electric field has to be stable at the 1% level over a time period of about 1000 s. Several sources of ambient ionizing radiation generate charged …
Mechanical And Morphological Characterization Of Energy Materials By Nanoindentation And Scanning Probe Microscopy, Jacob Hempel
Mechanical And Morphological Characterization Of Energy Materials By Nanoindentation And Scanning Probe Microscopy, Jacob Hempel
Theses and Dissertations--Physics and Astronomy
The demand for robust materials in energy-based applications such as solid electrolytes for batteries, piezoelectric composites for mechanical energy harvesting, or new polymer materials for polymer binders in composite electrodes is on the rise. Mechanical degradation is the most common way for devices to fail in operation, thus a thorough understanding of a material’s mechanical properties is essential for application purposes.
In this dissertation, the mechanical characterization of novel boron cluster solid electrolytes is presented. Therein, we determine the elastic modulus and hardness of these compounds using instrumented indentation. A comparison is made against other solid electrolytes. It is found …
Social Transformation During The Middle - Late Preclassic (1,000 Bce - 150 Bce) At Ucí, Yucatan Mexico, Daniel Vallejo-Cáliz
Social Transformation During The Middle - Late Preclassic (1,000 Bce - 150 Bce) At Ucí, Yucatan Mexico, Daniel Vallejo-Cáliz
Theses and Dissertations--Anthropology
The focus of this project is to track the social change developments in Ucí, Yucatan, Mexico, during the Middle (1,000 – 400 BCE) and Late Preclassic (400 – 150 BCE) that served as foundations to institutionalized hierarchy. This research is geared towards understanding if there were any expressions of social differentiation in the earliest, detectable moments in the history of Ucí, and what were the mechanisms used to eventually make distinctions permanent. Applying an agency approach, I argue that social actors may cause structural change, both consciously and inadvertently, through the application of several strategies aimed to enhancing their role …
Easing The Burden Of Survivors Of Domestic Violence Through The "One Family, One Judge" Court Model: Why Integrated Domestic Violence ("Idv") Courts Should Be Instituted Throughout The United States, Elka B. Blonder
Cardozo Journal of Equal Rights & Social Justice
The note advocates for the implementation of Integrated Domestic Violence (IDV) Courts nationwide, arguing that these courts provide a more efficient and supportive system for survivors of domestic violence by consolidating criminal, civil, and family cases under a single judge. This "one family, one judge" model aims to reduce the fragmentation and trauma survivors face in traditional court systems, offering a holistic approach that enhances survivor safety and offender accountability.
Evidence For A Single, Ancient Origin Of A Genus-Wide Alternative Life History Strategy, Kalle Tunström, Alyssa Woronik, Joseph J. Hanly, Pasi Rastas, Anton Chichvarkhin, Andrew D. Warren, Akito Kawahara, Sean D. Schoville, Vincent Ficarrotta, Adam H. Porter, Ward B. Watt, Arnaud Martin, Christopher W. Wheat
Evidence For A Single, Ancient Origin Of A Genus-Wide Alternative Life History Strategy, Kalle Tunström, Alyssa Woronik, Joseph J. Hanly, Pasi Rastas, Anton Chichvarkhin, Andrew D. Warren, Akito Kawahara, Sean D. Schoville, Vincent Ficarrotta, Adam H. Porter, Ward B. Watt, Arnaud Martin, Christopher W. Wheat
Biology Faculty Publications
Understanding the evolutionary origins and factors maintaining alternative life history strategies (ALHS) within species is a major goal of evolutionary research. While alternative alleles causing discrete ALHS are expected to purge or fix over time, one-third of the ~90 species of Colias butterflies are polymorphic for a female-limited ALHS called Alba. Whether Alba arose once, evolved in parallel, or has been exchanged among taxa is currently unknown. Using comparative genome-wide association study (GWAS) and population genomic analyses, we placed the genetic basis of Alba in time-calibrated phylogenomic framework, revealing that Alba evolved once near the base of the genus and …
The Business Of Securities Class Action Lawyering, Jessica M. Erickson, Stephen J. Choi, Adam C. Pritchard
The Business Of Securities Class Action Lawyering, Jessica M. Erickson, Stephen J. Choi, Adam C. Pritchard
Law Faculty Publications
Plaintiffs’ lawyers in the United States play a key role in combating corporate fraud. Shareholders who lose money as a result of fraud can file securities class actions to recover their losses, but most shareholders do not have enough money at stake to justify overseeing the cases filed on their behalf. As a result, plaintiffs’ lawyers control these cases, deciding which cases to file and how to litigate them. Recognizing the agency costs inherent in this model, the legal system relies on lead plaintiffs and judges to monitor these lawyers and protect the best interests of absent class members. Yet …
The Samuels-Buchanan Correspondence And The Lost Opportunity For A Positive Public Choice Scholarship, Luke Petach
The Samuels-Buchanan Correspondence And The Lost Opportunity For A Positive Public Choice Scholarship, Luke Petach
Funded Scholarship
This article revisits the debate between James Buchanan and Warren Samuels over Miller v. Schoene (1928). The initial court case—concerning the rights of government in the face of conflicting private interests—and subsequent debate between Buchanan and Samuels have important implications for the interrelations between legal and economic processes, the difference between a normative and positive theory of public choice, and the nature of public choice more generally. In published papers and private correspondence, the writings of Samuels reveal an alternative conception of public choice theory as a positive endeavor divorced from the free market normative implications of Buchanan’s work. Application …
The Design Of Primary Holding Magnet For The Lanl Neutron Electric Dipole Moment Experiment, Piya Amara Palamure
The Design Of Primary Holding Magnet For The Lanl Neutron Electric Dipole Moment Experiment, Piya Amara Palamure
Theses and Dissertations--Physics and Astronomy
The measurement of the permanent electric dipole moment of the neutron (nEDM) plays a significant role in searching for sources of beyond standard model CP violating physics. The goal of the Los Alamos National Laboratory (LANL) nEDM experiment is to push the upper limit of the nEDM to < 3 × 10−27 e·cm (68 % CL). A highly uniform magnetic field is key to achieving this sensitivity for the nEDM measurement by reducing the systematic uncertainties associated with the magnetic field non-uniformity. The B0 coil was designed to achieve a field uniformity of < 0.3 nT·m−1 at a nominal holding field of 1 µT. This document will outline a novel technique employed in the construction of the B0 coil using printed circuit boards (PCBs) and will present preliminary field maps obtained with the B0 coil housed in a magnetically shielded room (MSR) at LANL.
As Ultra Cold Neutrons (UCNs) move from the source to the measurement cells, the UCNs experience a large magnetic field gradient in the region between the layers of the MSR. This large gradient would otherwise cause depolarization of the UCNs. To mitigate this, a double cos θ coil will serve as the …
The Radial Quenching Progression Of Nearby Galaxies, Chenyu Zhao
The Radial Quenching Progression Of Nearby Galaxies, Chenyu Zhao
Theses and Dissertations--Physics and Astronomy
In this dissertation, we explore the spatial distribution of quiescent regions within galaxies using data from the Sloan Digital Sky Survey IV Mapping Nearby Galaxies at Apache Point Observatory (SDSS-IV MaNGA). Our analysis focuses on a radial range spanning from 0.3 R e to 1.2 R e and involves the development of innovative data selection and processing methods. Through this investigation, we identify two prominent types of transition galaxies: central-star-forming galaxies (C-SF galaxies) and central-quiescent galaxies (C-Q galaxies). Notably, we observe a correlation between galaxy mass and the predominant type of transition, with more massive galaxies tending to be C-Q …
Symbolic Computation Of Squared Amplitudes In High Energy Physics With Machine Learning, Abdulhakim Alnuqaydan
Symbolic Computation Of Squared Amplitudes In High Energy Physics With Machine Learning, Abdulhakim Alnuqaydan
Theses and Dissertations--Physics and Astronomy
The calculation of particle interaction squared amplitudes is a key step in the calculation of cross sections in high-energy physics. These complex calculations are currently performed using domain-specific symbolic algebra tools, where the computational time escalates rapidly with an increase in the number of loops and final state particles. This dissertation introduces an innovative approach: employing a transformer-based sequence-to-sequence model capable of accurately predicting squared amplitudes of Standard Model processes up to one-loop order when trained on symbolic sequence pairs. The primary objective of this work is to significantly reduce the computational time and, more importantly, develop a model that …
A Multidimensional View On The Emission-Line Diagnostics Of The Warm Ionized Gas In Nearby Galaxies, Xihan Ji
A Multidimensional View On The Emission-Line Diagnostics Of The Warm Ionized Gas In Nearby Galaxies, Xihan Ji
Theses and Dissertations--Physics and Astronomy
The baryonic cycle, being a fundamental process that shapes the cosmic ecosystem, describes the transformation and migration of baryonic matter in different phases. The warm ionized interstellar medium (ISM), defined as low-density gas that has temperature of the order of 10,000 K, represents an important link of the baryonic cycle and can be produced by a variety of energetic activities in galaxies, such as star formations, active galactic nuclei, and so forth. More importantly, the formation and evolution of the warm ionized gas not only traces the ongoing activities of the galaxies, but also reveals the past evolution of galaxies …
Investigations Of Epitaxial Heterostructures Of Layered Iridates With Resonant X-Ray Techniques, Sujan Shrestha
Investigations Of Epitaxial Heterostructures Of Layered Iridates With Resonant X-Ray Techniques, Sujan Shrestha
Theses and Dissertations--Physics and Astronomy
In layered 5d transition metal oxides, like Sr2IrO4, strong spin-orbit interaction comparable to the relevant interactions such as electron correlation and crystal field splitting provides fertile ground for emergent non-trivial phenomena. Some of these phenomena include metal-insulator transition, high-temperature superconductivity, and spin-orbit Mott insulator. The ground state is governed by the spin-orbit-entangled pseudospins Jeff =1/2, which have a significant orbital contribution. Therefore, magnetic exchange interactions and anisotropies are highly susceptible to external stimuli such as strain and heterointerface. As a result, it has a significant impact on the magnetic properties of the system. However, …
Too Close To The Ego: Narcissists’ Affective Reaction To Advertising Depends On Its Relevance To Self-Image, Yang He
Funded Scholarship
This research investigates the effect of narcissism on consumers’ affective reaction to advertising. Narcissists are burdened with the duality of the overinflated self-view and the vulnerability of the unrealistic ego. They tend to be paranoid of the mere introspection of self-image, because such introspection can expose the vulnerability they have been diligent to avoid. Therefore, ads that are closely relevant to the viewer’s self-image can lead to a negative affective response. Several experiments show support for this hypothesis and illustrate implications for advertising practice. Taking into consideration reports that narcissism is on the rise within the population, promotional ads that …
Time As A “Built-In Headwind”: The Disparate Impact Of Portfolio Cross-Assessment On Black Tyc Students, Annie M. Del Principe
Time As A “Built-In Headwind”: The Disparate Impact Of Portfolio Cross-Assessment On Black Tyc Students, Annie M. Del Principe
Publications and Research
This study of a departmental portfolio cross-assessment practice sheds light on factors that appear to influence assessment outcomes for Black students and helps to tease out some of the reasons why this assessment ecosystem has a disparate impact on these students. The findings, drawn from student outcomes data and student survey data, suggest that it isn’t only, or even primarily, Black students’ linguistic variety that leads to higher failure rates. The writing qualities most commonly flagged on Black students’ failing portfolios are likely related to the very different material conditions in which they write their papers. These conditions challenge the …
Impact Melt Rocks From The Late Paleocene Hiawatha Impact Structure, Northwest Greenland, William R. Hyde, Adam A. Garde, Nynke Keulen, Sebastian N. Malkki, Steven J. Jaret, Tod Waight, Pierre Beck, Iain Mcdonald, Nicolaj K. Larsen
Impact Melt Rocks From The Late Paleocene Hiawatha Impact Structure, Northwest Greenland, William R. Hyde, Adam A. Garde, Nynke Keulen, Sebastian N. Malkki, Steven J. Jaret, Tod Waight, Pierre Beck, Iain Mcdonald, Nicolaj K. Larsen
Publications and Research
Impact melt rocks formed during hypervelocity impact events are ideal for studying impact structures. Here, we describe impact melt rock samples collected proximal to the 31 km wide 58 Ma Hiawatha impact structure, northwest Greenland, which is completely covered by the Greenland Ice Sheet. The melt rocks contain diagnostic shock indicators (e.g., planar deformation features [PDF] in quartz and shocked zircon) and form three groups based on melt textures and chemistry: (i) hypocrystalline, (ii) glassy, and (iii) carbonate-based melt rocks. The exposed foreland directly in front of the structure consists of metasedimentary successions and igneous plutons; however, the carbonate-based impactites …
Humans Versus Robots: Converting Golf Putter Trajectories For Robotic Guidance, Stephen R. Bested, Valentin A. Crainic, Gerome A. Manson, Luc Tremblay
Humans Versus Robots: Converting Golf Putter Trajectories For Robotic Guidance, Stephen R. Bested, Valentin A. Crainic, Gerome A. Manson, Luc Tremblay
Medical Papers and Journal Articles
Robotic devices are used to provide physical guidance when teaching different movements. To advance our knowledge of robotic guidance in training complex movements, this investigation tested different kinematic data filtering methods of individual’s golf putts to convert them into trajectories to be employed by a robot arm. The purpose of the current study was to identify a simple filtering method to aptly replicate participants’ individual golf putter trajectories which could be used by the robot to execute them with greater consistency and accuracy than their human counterpart.
Participants putted towards 3 targets where three-dimensional data of the putter’s head was …
Personnel Selection: A Review Of Ways To Maximize Validity, Diversity, And The Applicant Experience, Chad H. Van Iddekinge, Filip Lievens, Paul R. Sackett
Personnel Selection: A Review Of Ways To Maximize Validity, Diversity, And The Applicant Experience, Chad H. Van Iddekinge, Filip Lievens, Paul R. Sackett
Research Collection Lee Kong Chian School Of Business
Personnel Psychology has a long tradition of publishing important research on personnel selection. In this article, we review some of the key questions and findings from studies published in the journal and in the selection literature more broadly. In doing so, we focus on the various decisions organizations face regarding selection procedure development (e.g., use multiple selection procedures, contextualize procedure content), administration (e.g., provide pre-test explanations, reveal target knowledge, skills, abilities, and other characteristics [KSAOs]), and scoring (e.g., weight predictors and criteria, use artificial intelligence). Further, we focus on how these decisions affect the validity of inferences drawn from the …
Cytological Diagnosis Of Pilomatrixoma And Its Diagnostic Pitfalls, Sabina Khan, Inara Abeer, Musharraf Husain, Sujata Jetley
Cytological Diagnosis Of Pilomatrixoma And Its Diagnostic Pitfalls, Sabina Khan, Inara Abeer, Musharraf Husain, Sujata Jetley
Faculty, Staff and Student Publications
BACKGROUND: Pilomatrixoma (PMX) is a relatively uncommon benign cutaneous neoplasm arising from skin adnexa. It presents as a subcutaneous asymptomatic nodule mostly in the head and neck region and is frequently misdiagnosed by the clinicians. Although easily diagnosed on histopathology, the cytologic features of PMX are less distinctive, depending on the stage and evolution of disease and may mimic other benign or even malignant lesions.
AIM: To study the cyto-morphological features of this uncommon neoplasm and identify its potential diagnostic pitfalls on fine needle aspiration cytology (FNAC).
MATERIAL AND METHODS: Archival records of histopathologically diagnosed Pilomatrixoma were analyzed during study …
Henry Gas Solubility Optimization Double Machine Learning Classifier For Neurosurgical Patients, Diana T Mosa, Amena Mahmoud, John Zaki, Shaymaa E Sorour, Shaker El-Sappagh, Tamer Abuhmed
Henry Gas Solubility Optimization Double Machine Learning Classifier For Neurosurgical Patients, Diana T Mosa, Amena Mahmoud, John Zaki, Shaymaa E Sorour, Shaker El-Sappagh, Tamer Abuhmed
Faculty, Staff and Student Publications
This study aims to predict head trauma outcome for Neurosurgical patients in children, adults, and elderly people. As Machine Learning (ML) algorithms are helpful in healthcare field, a comparative study of various ML techniques is developed. Several algorithms are utilized such as k-nearest neighbor, Random Forest (RF), C4.5, Artificial Neural Network, and Support Vector Machine (SVM). Their performance is assessed using anonymous patients' data. Then, a proposed double classifier based on Henry Gas Solubility Optimization (HGSO) is developed with Aquila optimizer (AQO). It is implemented for feature selection to classify patients' outcome status into four states. Those are mortality, morbidity, …
Vertical Structure And Trends In Co2 At The Cariaco Ocean Time Series Station: 1995-2017, Yrene M. Astor, Laura Lorenzoni, Digna T. Rueda-Roa, Frank E. Muller-Karger
Vertical Structure And Trends In Co2 At The Cariaco Ocean Time Series Station: 1995-2017, Yrene M. Astor, Laura Lorenzoni, Digna T. Rueda-Roa, Frank E. Muller-Karger
Marine Science Faculty Publications
Changes in the vertical structure of pH (total proton scale at 25 °C or pHT), total alkalinity, total CO2 (TCO2), and partial pressure of CO2 (pCO2) were examined at the CARIACO Ocean Time Series station (10º30'N, 64º40'W) from December 1995 to January 2017. Long-term trends were studied in the three water masses present in the Cariaco Basin: the surface layer (SL, located between 0-100 m depth), the Subtropical Underwater (SUW, with minimum depths between the surface and 105 m and maximums between 30-165 m depending on the season) and the deep water (DW, with minimum depths between 175-380 …
Retinal Alpha-Synuclein Accumulation Correlates With Retinal Dysfunction And Structural Thinning In The A53t Mouse Model Of Parkinson’S Disease, Katie K N Tran, Vickie H Y Wong, Anh Hoang, David I Finkelstein, Bang V Bui, Christine T O Nguyen
Retinal Alpha-Synuclein Accumulation Correlates With Retinal Dysfunction And Structural Thinning In The A53t Mouse Model Of Parkinson’S Disease, Katie K N Tran, Vickie H Y Wong, Anh Hoang, David I Finkelstein, Bang V Bui, Christine T O Nguyen
Faculty, Staff and Student Publications
Abnormal alpha-synuclein (α-SYN) protein deposition has long been recognized as one of the pathological hallmarks of Parkinson's disease's (PD). This study considers the potential utility of PD retinal biomarkers by investigating retinal changes in a well characterized PD model of α-SYN overexpression and how these correspond to the presence of retinal α-SYN. Transgenic A53T homozygous (HOM) mice overexpressing human α-SYN and wildtype (WT) control littermates were assessed at 4, 6, and 14 months of age (male and female,
Adrenal Venous Sampling In Primary Aldosteronism: Single-Centre Experience From Western India, Krantikumar Rathod, Saba S Memon, Punit Mahajan, Anurag Lila, Dhaval Thakkar, Hemant Deshmukh, Tushar Bandgar
Adrenal Venous Sampling In Primary Aldosteronism: Single-Centre Experience From Western India, Krantikumar Rathod, Saba S Memon, Punit Mahajan, Anurag Lila, Dhaval Thakkar, Hemant Deshmukh, Tushar Bandgar
Faculty, Staff and Student Publications
INTRODUCTION: The protocols and criteria used for adrenal venous sampling (AVS) differ across centres. There are no studies from the Indian subcontinent describing AVS-based outcomes in primary aldosteronism (PA). We aim to describe our experience from a single centre.
METHODS: Retrospective records from 2018 to 2020 of patients with confirmed PA who underwent AVS were reviewed. Clinical, imaging, AVS data and outcomes (as per PASO criteria) were recorded. AVS was performed by sequential sampling with cosyntropin stimulation with intraprocedural cortisol and cut-off of selectivity >5 and lateralization >4 by a single radiologist.
RESULTS: Fifteen patients with median age of 50 …
Effect Of Concurrent Mitral Valve Surgery For Secondary Mitral Regurgitation Upon Mortality After Aortic Valve Replacement Or Coronary Artery Bypass Surgery, Shyamal R Asher, Chin Siang Ong, Raymond J Malapero, Mahyar Heydarpour, Gregory W Malzberg, Jasmine T Shahram, Thy B Nguyen, Douglas C Shook, Stanton K Shernan, Prem Shekar, Tsuyoshi Kaneko, Rodolfo Citro, Jochen D Muehlschlegel, Simon C Body
Effect Of Concurrent Mitral Valve Surgery For Secondary Mitral Regurgitation Upon Mortality After Aortic Valve Replacement Or Coronary Artery Bypass Surgery, Shyamal R Asher, Chin Siang Ong, Raymond J Malapero, Mahyar Heydarpour, Gregory W Malzberg, Jasmine T Shahram, Thy B Nguyen, Douglas C Shook, Stanton K Shernan, Prem Shekar, Tsuyoshi Kaneko, Rodolfo Citro, Jochen D Muehlschlegel, Simon C Body
Faculty, Staff and Student Publications
OBJECTIVES: It is uncertain whether concurrent mitral valve repair or replacement for moderate or greater secondary mitral regurgitation at the time of coronary artery bypass graft or aortic valve replacement surgery improves long-term survival.
METHODS: Patients undergoing coronary artery bypass graft and/or aortic valve replacement surgery with moderate or greater secondary mitral regurgitation were reviewed. The effect of concurrent mitral valve repair or replacement upon long-term mortality was assessed while accounting for patient and operative characteristics and mitral regurgitation severity.
RESULTS: Of 1,515 patients, 938 underwent coronary artery bypass graft or aortic valve replacement surgery alone and 577 underwent concurrent …
Antimicrobial Activity Of Plasma Rich In Platelets (Prp) On The Ocular Microbiota Of Healthy Horses From Minas Gerais, Luis E C Torres, Camilo O Florez, Jéssica G Oliveira, Giovanna D Vieira, Ilza S Ribeiro, Kelly M Keller, Fabíola O P Leme, Priscila Fantini, Renata P A Maranhão
Antimicrobial Activity Of Plasma Rich In Platelets (Prp) On The Ocular Microbiota Of Healthy Horses From Minas Gerais, Luis E C Torres, Camilo O Florez, Jéssica G Oliveira, Giovanna D Vieira, Ilza S Ribeiro, Kelly M Keller, Fabíola O P Leme, Priscila Fantini, Renata P A Maranhão
Faculty, Staff and Student Publications
In equine ophthalmology, ulcerative keratitis is among the most common conditions and, in general, arises as a consequence of some trauma suffered. Secondarily, subsequent contamination by pathogenic or resident bacteria of the horse's ocular microbiota may have undesirable consequences. Under physiological conditions, the normal microbiota coexists with the immune status of the host, serving as a barrier, ensuring the health of the ocular surface, and inhibiting the proliferation of pathogens. However, in the imbalance of immune barriers, the normal microbiota can become pathogenic and lead to infection, acting as an opportunistic agent. The present study aims to demonstrate the antimicrobial …
Assessing The Relationships Between Direct And Vicarious Exposure To Healthcare Discrimination And Erasure, Mistrust In Healthcare, And The Healthcare Utilization Behaviors Among Transgender And Gender Independent Individuals, Kyle L. Mason
Theses and Dissertations
Healthcare inaccessibility through direct exposure (i.e., personal) to myriad forms of gender identity-related discrimination and erasure among the Transgender and Gender Independent (TGI) population has been documented by prior studies. The myriad barriers that individuals who embody TGI identities encounter to accessing healthcare are associated with the underutilization of healthcare, which may further exacerbate the health disparities that exist between this population and cisgender individuals in the United States (U.S.). Although the impacts of the harm that direct exposure to healthcare discrimination and erasure may have on TGI individuals are known, their exposure to such harm vicariously (i.e., through observation …
Exosomal Lipid Biomarkers Of Oligodendrocyte Pathology To Predict Scoliosis In Children With Cerebral Palsy, Nune Darbinian, Emily C Sparks, Armine Darbinyan, Nana Merabova, Tamara Tatevosian-Geller, Katie Calaku, Sarah Bachman, Huaqing Zhao, Shohreh Amini, Laura Goetzl, Solomon P Samuel, Amer Samdani, Michael E Selzer
Exosomal Lipid Biomarkers Of Oligodendrocyte Pathology To Predict Scoliosis In Children With Cerebral Palsy, Nune Darbinian, Emily C Sparks, Armine Darbinyan, Nana Merabova, Tamara Tatevosian-Geller, Katie Calaku, Sarah Bachman, Huaqing Zhao, Shohreh Amini, Laura Goetzl, Solomon P Samuel, Amer Samdani, Michael E Selzer
Faculty, Staff and Student Publications
INTRODUCTION: Cerebral Palsy (CP), the most common cause of disability in children, is phenotypically heterogeneous. Approximately 20% of cases develop severe scoliosis. A pathological hallmark of CP is periventricular leukomalacia (PVL), which is due to dysmyelination, suggesting the possibility of a lipidomic abnormality. Risk factors for CP include perinatal hypoxia, prematurity, multiple gestation, ischemia, infection, and maternal alcohol consumption. There is evidence for low serum levels of omega-3 (ω-3) fatty acids in CP patients, and separately in idiopathic scoliosis. Many effects of free fatty acids (FFAs) are mediated via specific G protein-coupled free fatty acid receptors (FFARs), which play essential …
Maternal Blood Lipid Biomarkers Of Oligodendrocyte Pathology To Predict Fetal Alcohol Spectrum Disorders, Nune Darbinian, Emily C Sparks, Armine Darbinyan, Nana Merabova, Gabriel Tatevosian, Ekaterina Vadachkoria, Huaqing Zhao, Shohreh Amini, Laura Goetzl, Michael E Selzer
Maternal Blood Lipid Biomarkers Of Oligodendrocyte Pathology To Predict Fetal Alcohol Spectrum Disorders, Nune Darbinian, Emily C Sparks, Armine Darbinyan, Nana Merabova, Gabriel Tatevosian, Ekaterina Vadachkoria, Huaqing Zhao, Shohreh Amini, Laura Goetzl, Michael E Selzer
Faculty, Staff and Student Publications
INTRODUCTION: Up to 9.9% of children have fetal alcohol spectrum disorders (FASD), the most frequent cause of intellectual disability in the US. FASD may involve abnormal brain development, including dysmyelination, suggesting abnormal development of oligodendrocytes (OLs), which make myelin and are rich in lipids. Indeed, low serum levels of omega-3 fatty acids (ω-3) have been reported in FASD. Free fatty acids bind to specific receptors (FFARs). We have isolated cell type-specific fetal brain-derived exosomes (FB-E) from maternal blood and sampled their contents to search for lipid-related biomarkers that predict FASD.
METHODS: Blood samples were collected from two groups of pregnant …
Documenting Range Expansion Of Two Invasive Tick (Acari:Ixodidae) Species In Eastern South Dakota, Braden Wojahn
Documenting Range Expansion Of Two Invasive Tick (Acari:Ixodidae) Species In Eastern South Dakota, Braden Wojahn
Dissertations and Theses
This project documents the expanded zoogeographic ranges of the blacklegged tick (Ixodes scapularis) and lone star tick (Amblyomma americanum) within eastern South Dakota. Ticks are important when considering a “One Health” approach, as many species are competent vectors of zoonotic pathogens causing human diseases and conditions such as Lyme disease, tularemia, rickettsia, and alpha gal syndrome. The research involved constitutes two steps. First, tick surveillance was conducted in eastern counties of South Dakota, spanning March 2021 through August 2022. Surveillance took place along edge habitat at recreation areas, state and public parks, wildlife management areas and refuges, and other natural …
Research On Cloud Manufacturing Service Recommendation Based On Graph Neural Network, Minghui Li, Xiaoqiu Shi, Yuqiang Shi, Yong Cai, Xuewen Dong
Research On Cloud Manufacturing Service Recommendation Based On Graph Neural Network, Minghui Li, Xiaoqiu Shi, Yuqiang Shi, Yong Cai, Xuewen Dong
Faculty, Staff and Student Publications
There are an increasing number of manufacturing service resources appeared on the cloud manufacturing (CMfg) service platform recently, which leads to a serious information overloading problem to the enterprises that need these resources. To tackle this problem, a graph neural network-based recommendation method for CMfg service resources is proposed, which effectively overcomes some limitations of the traditional recommendation methods. Specifically, we first use different similarity calculation methods (e.g., Cosine similarity, Pearson correlation coefficient, etc.) to calculate the similarities between different resources based on the feature information of CMfg service resources. A resource graph dataset is accordingly established. A graph neural …