Digital Commons Network^™

Frailty In End-Stage Liver Disease: Understanding Pathophysiology, Tools For Assessment, And Strategies For Management, Mazen Elsheikh, Ahmed El Sabagh, Islam B Mohamed, Megha Bhongade, Manal M Hassan, Prasun Kumar Jalal

Faculty, Staff and Students Publications

Frailty and sarcopenia are frequently observed in patients with end-stage liver disease. Frailty is a complex condition that arises from deteriorations across various physiological systems, including the musculoskeletal, cardiovascular, and immune systems, resulting in a reduced ability of the body to withstand stressors. This condition is associated with declined resilience and increased vulnerability to negative outcomes, including disability, hospitalization, and mortality. In cirrhotic patients, frailty is influenced by multiple factors, such as hyperammonemia, hormonal imbalance, malnutrition, ascites, hepatic encephalopathy, and alcohol intake. Assessing frailty is crucial in predicting morbidity and mortality in cirrhotic patients. It can aid in making critical …

Construction Of A Human Pangenome Reference To Improve Structural Variation Detection, Wen-Wei Liao

Arts & Sciences Graduate Student Theses and Dissertations

Structural variants (SVs) significantly contribute to genetic diversity among individuals and impact gene regulation, disease, and evolution. The predominant approach to profiling these genetic variants in large-scale population studies is through short-read whole-genome sequencing (WGS). This approach involves sequencing millions of short reads, aligning them to a linear reference genome, and subsequently identifying variants relative to this reference. However, its capability to detect SVs, especially long insertions and complex rearrangements, is limited. The primary limitation arises from the insufficient representation of structural diversity across human populations in the linear reference genome. As a result, short reads derived from non-reference SVs …

Characterizing The Evaporating Droplets Over Heterogeneous Wettability Surfaces, Xi Li

Theses

This work investigates deposition patterns left by evaporating particle-laden droplets on heterogeneous surfaces with spatially varying wettability. Spatial differences in receding contact angles give rise to scalloped-shaped contact lines. During evaporation, the contact line recedes in one location and remains pinned in another. This non-uniform contact line recession results in particle self-assembly above areas where the contact line remains pinned, but not where it recedes. This behavior is fairly robust across a variety of particle sizes, concentrations, and device geometries. We hypothesize that particle self-assembly in these cases is due to the competition between particle diffusion and the evaporative-driven advective …

Fintech And Entrepreneurship: An Assessment Model To Evaluate Policy Instruments For Fintech Adoption By Small And Medium Enterprises (Smes), Deemah Abdullah Alassaf

Dissertations and Theses

Small and medium enterprises (SMEs) are the engines that drive economic development. They are the backbone of the middle class as they provide social stability, innovation, inclusive growth, and poverty alleviation. SMEs contribute significantly to job creation, employment, tax provision and the Gross Domestic Product (GDP). However, they face inferior conditions and challenges when it comes to their financing compared to that of large enterprises, as well as having a high expectancy of failing. Because of these limitations, SMEs tend to grow slowly since building up higher credit is difficult for them, and in addition to this, they lack access …

Truth Or Consequences: Academic Instruction Librarians As Information Literacy And Critical Thinking Activists, Laureen P. Cantwell-Jurkovic, Heather F. Ball

Communications in Information Literacy

The graphic edition of Snyder’s On Tyranny (2021) states "truth dies in four modes," which is a contemporary synthesis connected to Klemperer's Language of the Third Reich (1957). The researchers connected these four modes to information literacy (IL) instruction—but would others? The researchers surveyed academic librarians engaged in IL instruction on whether they felt they addressed any of the modes in their work. The researchers also asked whether they believe the ACRL Framework for Information Literacy for Higher Education works to circumvent any of the four modes. Nearly 150 librarians responded and, while most respondents were unfamiliar with the two …

Race: An Efficient Redundancy-Aware Accelerator For Dynamic Graph Neural Network, Hui Yu, Yu Zhang, Jin Zhao, Yujian Liao, Zhiying Huang, Donghao He, Lin Gu, Hai Jin, Xiaofei Liao, Haikun Liu, Bingsheng He, Jianhui Yue

Michigan Tech Publications

Dynamic Graph Neural Network (DGNN) has recently attracted a significant amount of research attention from various domains, because most real-world graphs are inherently dynamic. Despite many research efforts, for DGNN, existing hardware/software solutions still suffer significantly from redundant computation and memory access overhead, because they need to irregularly access and recompute all graph data of each graph snapshot. To address these issues, we propose an efficient redundancy-aware accelerator, RACE, which enables energy-efficient execution of DGNN models. Specifically, we propose a redundancy-aware incremental execution approach into the accelerator design for DGNN to instantly achieve the output features of the latest graph …

Does Patella Lowering As Part Of Multilevel Surgery Improve Knee Kinematics In Children With Cerebral Palsy And Crouch Gait? A Meta-Analysis Of Comparative Studies, María Galán-Olleros, Sergio Lerma-Lara, Beltran Torres-Izquierdo, Ana Ramírez-Barragán, Rosa M Egea-Gámez, Pooya Hosseinzadeh, Ignacio Martínez-Caballero

2020-Current year OA Pubs

PURPOSE: To evaluate differences in knee kinematic outcomes of patellar-lowering surgery, specifically patellar tendon advancement or patellar tendon shortening, compared with no-patellar-lowering surgery in multilevel surgery for children with cerebral palsy and crouch gait.

METHODS: Four databases were searched to retrieve studies published from inception until 2023. Three reviewers independently screened for studies with observational or randomized control designs, comparing two groups of patients with cerebral palsy and crouch gait who underwent multilevel surgery (with patellar-lowering surgery versus no-patellar-lowering surgery), where various gait analysis outcomes were reported (CRD42023450692). The risk of bias was assessed with the Risk Of Bias In …

Multilayer Perceptron Modeling For Social Dysfunction Prediction Based On General Health Factors In An Iranian Women Sample, Sajjad Bagheri, Sarvenaz Taridashti, Hojjatollah Farahani, Peter Watson, Elham Rezvani

Department of Psychology Faculty Scholarship and Creative Works

In the year 2022, this research conducted an in-person study involving 780 single or widowed women, aged between 20 and 70, falling within the bottom three economic deciles and possessing varying levels of education. All participants held educational qualifications below a high school diploma and were beneficiaries of charitable financial support in Khorasan province, Iran. The study aimed to investigate the predictive factors of social dysfunction in this specific demographic. Data collection spanned a 12-month period throughout 2022, with participants completing the GHQ-28 questionnaire during their visits to the charity office. Clinical in-person interviews were also conducted to gather comprehensive …

Floating Wind Farm Experiments Through Scaling For Wake Characterization, Power Extraction, And Turbine Dynamics, Juliaan Bossuyt, OndˇRej FercˇÁk, Zein Sadek, Charles Meneveau, Dennice Gayme, Raúl Bayoán Cal

Mechanical and Materials Engineering Faculty Publications and Presentations

In this study, wind and water tunnel experiments of turbulent wakes in a scaled floating wind farm are performed. Scaling of a floating wind farm with a scaling ratio of 1:400 is made possible by relaxing geometric scaling of the turbine platform system, such that the dynamic response can be correctly matched, and to allow for relaxing Froude scaling such that the Reynolds number can be kept large enough. Four dimensionless parameters, describing the relative importance of wind and wave loads compared to turbine inertia, are used to guide the scaled floater design. Free decay tests of the pitch and …

Deep Learning-Based Phenotyping Reclassifies Combined Hepatocellular-Cholangiocarcinoma, Julien Calderaro, Pooja Navale, Et Al.

2020-Current year OA Pubs

Primary liver cancer arises either from hepatocytic or biliary lineage cells, giving rise to hepatocellular carcinoma (HCC) or intrahepatic cholangiocarcinoma (ICCA). Combined hepatocellular- cholangiocarcinomas (cHCC-CCA) exhibit equivocal or mixed features of both, causing diagnostic uncertainty and difficulty in determining proper management. Here, we perform a comprehensive deep learning-based phenotyping of multiple cohorts of patients. We show that deep learning can reproduce the diagnosis of HCC vs. CCA with a high performance. We analyze a series of 405 cHCC-CCA patients and demonstrate that the model can reclassify the tumors as HCC or ICCA, and that the predictions are consistent with clinical …

Leading Transformational Change By Living Transformational Change: Seven Structures Of Successful Innovation In Doctoral Education, Rebecca Farley, Jennifer Dinielli

Transform

Transformational change is vital to the sustainability of all individuals and organizations. This qualitative historical study of the Brandman University Doctoral Program in Organizational Leadership utilized the Bolman and Deal (2017) four-frame change model to examine the evolution of the program from 2013 through 2017. Findings from the study indicate seven key structures of the doctoral program had the greatest impact on the program’s successful transition from start-up to the refinement and scaling phases. This study contributes to the literature on transformational change and doctoral education by providing detailed analysis of critical factors of the program’s successful transformation in the …

Covid, Church, & Cuts: A Single Narrative Case Study Of Pandemic Impacts On A Bi-Vocational Pastor & Barber, A. D. Hooker, Camille S. Talbert

The Journal of Faith, Education, and Community

This narrative case study provides an in-depth look into the impacts of the COVID-19 Pandemic from the perspective of an assistant pastor with a small African American church in an urban city. His story indicates that the pandemic had both positive and negative effects on the pastor’s ability to carry out his role of pastoral care and ministry. Some positives were the results of new technological adaptations that helped to improve members’ consistency in attending and participating in weekly services. Some negative effects imposed by COVID-19 was the revelation of imbalanced relationships and a lack of trust in God. The …

Sharp Stick Grasps At Autistic Women’S Liminal Vulnerability, Meaghan Krazinski

Ought: The Journal of Autistic Culture

This film analysis of Sharp Stick by Lena Dunham critically explores how the film uptakes representations of the ideas around the vulnerabilities of Autistic women in popular culture, and yet does not explicitly name them as such. This liminality is critical and plays into the intersectional analysis that the author engages around the way vulnerability and Autistic identity is interpreted and read. The author draws upon McDermott's (2022) "neurotypical gaze" in an analysis that shows how traditional tropes around Autistic women’s vulnerability are social constructions that are brought into relief by stereotypes around race, gender, and ability. The author uses …

Critical Autism Studies Beyond Academia: An Annotated List, Alyssa Hillary Zisk

Ought: The Journal of Autistic Culture

This is an introduced and annotated list of sources from beyond academia which are, have been, or may yet be important texts for critical autism or neurodiversity studies. The defining actions of critical autism studies, or of critical neurodiversity studies, have been taken outside academia and will continue to be taken outside academia. This list serves as a reminder of this reality through examples.

How Animal Assisted Therapy With Dogs Is Understood And Perceived Among Health Care Providers And The General Public In Canada, Healey Gardiner Dr., Jill Singleton-Jackson Dr.

Journal of Counseling and Psychology

When a dog is included in treatment to meet an individual’s therapeutic goal it is known as Animal-Assisted Therapy (AAT). Although AAT has increased in popularity, limited research exists regarding its efficacy. According to the diffusion of innovation theory an innovation must be properly communicated to all appropriate channels before it may be adopted into practice. Little is known about how AAT is understood and perceived among healthcare professional and public populations in Canada. In the present study, health care professionals and the general public in Canada were surveyed. Attitude toward dogs, openness to experience, agreeableness, and subjective distress were …

Grace Community Church Council Minutes 2015-2023, Grace Community United Methodist Church, Fort Mill

Methodist Local Church Records

No abstract provided.

Early Management Of Nutritional Deficiencies To Reduce Musculoskeletal Disabilities Of Pediatric Populations In Africa, Kristin Freitas, Justin Gambini, Curt C. Stilp, Kara Roman, Ryan Mather

Doctor of Medical Science (DMSc)

An estimated 1.3 billion individuals live with disabilities across the world, however many of these impairments are developed throughout childhood and could be prevented or treated with prompt and early intervention. In Africa, nutritional deficiencies are a common reason for disability in pediatric populations, often due to a limited supply of resources and diets high in grains and beans. This results in the development of genu varum and valgum deformities, which are most commonly caused by rickets attributed to calcium deficiencies in these areas. The children often go untreated, evidently causing musculoskeletal disabilities and further complications of osteomalacia or fractures …

Investment Behavior: The Difference Between Individual And Professional Investors, Saketh Dantuluri

Honors Projects in Finance

In the modern world, there is greater accessibility to information and investment opportunities. This has led to more people from many different backgrounds to start investing in various markets. Because of this, the modem-day investor can look like many different things and have significantly varied levels of financial knowledge. This study will look into the differences in investment behaviors for individual investors, who typically have lower financial literacy rates, and professional investors, who typically have higher financial literacy rates. The data will be obtained by surveying individuals with various financial literacy rates in order to gauge the differences between individual …

Rolando Hernandez-Martinez V. Attorney General United States Of America

2023 Decisions

Agency

Critical Edition: A Commentary Upon The Prophecie Of Isaiah, Grace Weaver

University Honors Papers

A Commentary Upon the Prophecie of Isaiah, written by John Calvin, was first published in French in 1551. John Calvin (b. 7.10.1509 in France; d. 5.27.1564 in Geneva) was a prominent protestant reformer in Europe. Throughout his life, he published apologies and commentaries on many biblical books and religious texts, and became a notorious figurehead of the time. As a significantly controversial figure, Calvin and his work faced censorship and ridicule by Catholics outraged at the growing Christian Reformation of the 16th Century. A little over seven years after its initial publication, a second edition of A Commentary Upon the …

Mastery Learning: Second Chances, Instructor Workload, And Student Confidence, Judith Puncochar

Conference Presentations

No abstract provided.

Critical Edition Of The Summe Of Christian Religion Delivered By Zacharias Ursinua, Taylor Trenta

University Honors Papers

Originally delivered by Zacharius Ursinus along with his work on the Heidelberg Catechism, The Summe of Christian Religion is an expansion on his contributions to the literature of Christian faith. The version, translated to English by Henry Parry, contributes to the depth of this reformed way of thinking across sixteenth to seventeenth century Western Europe; presented in the form of questions and explanations, this type of religious text is important for expanding on theological thoughts.

Tikaram And Chandrakala Dhananjaya: A Collaborative Couple In Mathematics From Nepal, Deepak Basyal, Brigitte Stenhouse

Mathematics and Statistics

Within the history of mathematics and mathematics education in Nepal, Tikaram and Chandrakala Dhananjaya are relatively well-known figures for their two books Śiśubodha Taraṅgiṇī and Līlāvatī. This is despite there being almost no archival or manuscript materials offering a window into their lives: we have no letters, notebooks, diaries, or school records. Rather than focusing on either individual in isolation, in this article we present an argument for considering the Dhananjayas as an analytically indivisible collaborative couple in mathematics. Of the two aforementioned books, one is attributed to Chandrakala and the other to Tikaram; but in fact, both are translations …

Closing The Gaps In Care Of Dyslipidemia: Revolutionizing Management With Digital Health And Innovative Care Models, Samuel J. Apple, Rachel Clark, Jonathan Daich, Macarena Lopez Gonzalez, Robert J. Ostfeld, Peter P. Toth, Vera Bittner, Seth S. Martin, Jamal S. Rana, Salim S. Virani

Office of the Provost

Although great progress has been made in the diagnostic and treatment options for dyslipidemias, unawareness, underdiagnosis and undertreatment of these disorders remain a significant global health concern. Growth in digital applications and newer models of care provide novel tools to improve the management of chronic conditions such as dyslipidemia. In this review, we discuss the evolving landscape of lipid management in the 21st century, current treatment gaps and possible solutions through digital health and new models of care. Our discussion begins with the history and development of value-based care and the national establishment of quality metrics for various chronic conditions. …

Psycholinguistic Factors Of Incel Cognition, Molly R. Johnson

Walden Dissertations and Doctoral Studies

No abstract provided.

Fs Social Justice Committee Agenda, Northern Illinois University

Faculty Senate Archives

No abstract provided.

A Pilot Study In Healthcare: Salivary Cortisol Levels And Burnout, Hannah Oggerino

Graduate Theses & Non-Theses

This pilot study investigated levels of burnout in non-clinical workers in a healthcare setting and compared them to salivary cortisol concentrations. Mashlach’s Burnout Inventory-Human Service Survey for Medical Personnel (MBI-HSS(MP)) was used to evaluate self-perceived levels of burnout and saliva samples were collected to determine cortisol concentrations at four times during participants’ shift. The study was comprised of subjects exposed to multiple high-stress factors, including working in a healthcare setting, post-COVID ramifications, and demographic effects of Montana. The data revealed a statistically significant correlation (P-value < 0.05) between morning salivary cortisol secretion concentrations and mean survey scores. Significance (P-value < 0.05) was also found between the three dimensions measured by the MBI-HSS(MP): burnout, depersonalization, and personal achievement. The study discusses several limitations that should be considered when interpreting results. Findings do suggest that future investigation among this group is needed. Results may help guide interventions that support the mental health and wellbeing of medical support personnel, reduce stress, and avoid burnout.

Gravity Fed Bathymetry Agnostic Wave System Innovation & Responsive Surf Fin Development, Erik Casagranda

Graduate Theses & Non-Theses

This project investigates the integration of hydrodynamically responsive surf fins into wake-surf boards, focusing on optimizing performance for wake-surf waves by utilizing fluid dynamic and spring force principles. Additionally, the research explores the development of a novel stationary wave system, adopting a 'Gravity Fed Bathymetry Agnostic' approach, enabling year-round surfing in indoor facilities and addressing the limitations of existing manmade wave technologies. The initial phase involved testing the feasibility of a scaled model for the gravity-fed bathymetry-agnostic wave system. While the wave system demonstrated success on a model scale, an evaluation of its feasibility at full scale was conducted, and …

Haiti: Confronting An Immense Challenge, Irwin Stotzky

University of Miami Inter-American Law Review

This article analyzes the history of Haiti, from its origins as a slave colony of France, which was the richest colony in the Americas, to its war of independence leading to the first Black independent nation in the Americas, to its economic re-enslavement under the power of France and then the United States. The article discusses the great harm the French caused the Haitian people by imposing through force a ransom of billions of dollars that has led Haiti to its present position of being on the brink of becoming a failed state, with all of the disastrous consequences for …

Redress For Historical Injustices: Haiti’S Claim For The Restitution Of Post-Independence Payments To France, Günther Handl

University of Miami Inter-American Law Review

No abstract provided.