Digital Commons Network^™

Financial Burden Of Men With Localized Prostate Cancer: A Process Paper, Ashley J Housten, Hannah E Rice, Su-Hsin Chang, Allison J L'Hotta, Eric H Kim, Bettina F Drake, Robin Wright-Jones, Mary C Politi

2020-Current year OA Pubs

BACKGROUND: Many individuals undergoing cancer treatment experience substantial financial hardship, often referred to as financial toxicity (FT). Those undergoing prostate cancer treatment may experience FT and its impact can exacerbate disparate health outcomes. Localized prostate cancer treatment options include: radiation, surgery, and/or active surveillance. Quality of life tradeoffs and costs differ between treatment options. In this project, our aim was to quantify direct healthcare costs to support patients and clinicians as they discuss prostate cancer treatment options. We provide the transparent steps to estimate healthcare costs associated with treatment for localized prostate cancer among the privately insured population using a …

Adapting A Mobile App To Support Patients With Anorexia Nervosa Following Post-Acute Care: Perspectives From Eating Disorder Treatment Center Stakeholders, Anneliese Haas, Agatha A Laboe, Claire G Mcginnis, Marie-Laure Firebaugh, Jillian Shah, Anna M Bardone-Cone, Kathleen M Pike, C Barr Taylor, Denise E Wilfley, Ellen E Fitzsimmons-Craft

2020-Current year OA Pubs

INTRODUCTION: Anorexia nervosa (AN) is a harmful, life-threatening illness. Patients with severe AN often receive acute treatment but, upon discharge, experience high relapse rates. Evidence-based, outpatient treatment following acute care is critical to preventing relapse; however, numerous barriers (e.g., location, financial limitations, low availability of providers) preclude individuals from accessing treatment. mHealth technologies may help to address these barriers, but research on such digital approaches for those with AN is limited. Further, such technologies should be developed with all relevant stakeholder input considered from the outset. As such, the present study aimed to garner feedback from eating disorder (ED) treatment …

Waterbodies Thermal Energy Based Systems Interactions With Marine Environment — A Review, Amir Bordbar, Konstantinos Georgoulas, Yong Ming Dai, Simone Michele, Frank Roberts, Nigel Carter, Yeaw Chu Lee

School of Engineering, Computing and Mathematics

Waterbodies’ thermal energy potential, as a green, renewable, and limitless source of energy, can be exploited in response to the growing energy demands of islands and coastal cities. Up to now, the technologies that have been developed for this purpose include seawater air-conditioning, surface water heat pump, and ocean energy thermal conversion systems or their combinations, which are presented here as Waterbodies Thermal Energy Based Systems (WTEBSs). The growth and development of these technologies raise concerns regarding their potential impacts on sustainability of the marine environment. The present work provides a comprehensive review of the available literature and state-of-the-art technologies …

Isotopic Signatures Of Plutonium In The Global Cryosphere, Edyta Łokas, Giovanni Baccolo, Caroline Clason, Przemysław Wachniew, Nozomu Takeuchi, Krzysztof Zawierucha, Dylan Beard, Roberto Ambrosini, Francesca Pittino, Andrea Franzetti, Philip Owens, Anna Cwanek, Katarzyna Koltonik

School of Geography, Earth and Environmental Sciences

No abstract provided.

Development Of A Goal Setting And Goal Management System: Intervention Mapping, Eunyoung Kang, Erin R Foster

2020-Current year OA Pubs

BACKGROUND: Although goal setting and goal management (GSGM) is a key component of chronic disease management and rehabilitation practice, there is currently no widely used evidence-based intervention system available. This paper describes the theoretical underpinnings and development of a new intervention called MyGoals. MyGoals is designed to guide occupational therapy (OT) practitioners to implement theory-based, client-engaged GSGM for adults with chronic conditions in community-based OT rehabilitation settings.

METHODS: We first developed a planning team with two adults with chronic conditions, two clinicians, and two researchers. As a collaborative team, we co-developed MyGoals by following Intervention Mapping (IM) steps 1-4 and …

Situating Implementation Science (Is) In Res(Is)Tance: A Conceptual Frame Toward The Integration Of Scholarship From The Black Radical Tradition, Cory D Bradley, Whitney C Irie, Elvin H Geng

2020-Current year OA Pubs

This manuscript undertakes a disciplinary self-critique of the field of implementation science, a field which attempts to bridge the gap between evidence-based interventions and their practical application. Despite the heightened emphasis on health equity and racial disparities, the field's current discourse is limited by key epistemic shortcomings. First, even though prevalence of implementation gaps between racialized groups in the United States necessitates a comprehensive understanding of the systems perpetuating these disparities, the field does not operate with a general explanation for disparities not as a failure of systems, but a system historically and structural designed to produce disparities. Second, the …

Guiding Principles For Effective Collaborative Implementation Strategies For Multisite Hospital Improvement Initiatives: A Mixed-Method Realist Evaluation Of Collaborative Strategies Used In Four Multisite Initiatives At Public Hospitals In New South Wales, Australia, Janet C. Long, Mitchell N. Sarkies, Emilie Francis-Auton, Natalie Roberts, Rebecca Hardwick, Hoa Mi Nguyen, Jean Frederic Levesque, Diane E. Watson, Johanna Westbrook, Peter D. Hibbert, Frances Rapport, Jeffrey Braithwaite

Peninsula Medical School

Objective Large-scale, multisite hospital improvement initiatives can advance high-quality care for patients. Implementation support is key to adoption of change in this context. Strategies that foster collaboration within local teams, across sites and between initiative developers and users are important. However not all implementation strategies are successful in all settings, sometimes realising poor or unintended outcomes. Our objective here is to develop guiding principles for effective collaborative implementation strategies for multi-site hospital initiatives. Design Mixed-method realist evaluation. Realist studies aim to examine the underlying theories that explain differing outcomes, identifying mechanisms and contextual factors that may trigger them. Setting We …

Bottle With A Message: The Role Of Story Writing As An Engagement Tool To Explore Children's Perceptions Of Marine Plastic Litter, Estelle Praet, Jostein Baeza-Álvarez, Veer D De, Geraldine Holtmann-Ahumada, Jen S. Jones, Sarah Langford, Jessica Michel Dearte, John Schofield, Martin Thiel, Kayleigh J. Wyles

School of Psychology

As human behaviors play a crucial role in addressing the global threat of plastic pollution, it is vital to understand perceptions about marine plastic litter (MPL) and to develop interventions encouraging pro-environmental behaviors (PEBs). This study evaluates story writing as a window to explore perceptions and as an engagement activity to boost PEBs. During the COVID-19 lockdowns, schoolchildren from the East Pacific coast participated in this activity, each creating a story and answering a pre-post survey. Qualitative and quantitative analysis of 81 stories and 79 surveys show awareness of sources and impacts. Participants identified land and local pollution as significant …

When Reputation Is At Stake: Honour, Masculinity And Militarism In The Courts Martial Records Of The Marine Corps, 1755 – 1779, Lee-Jane Giles

School of Law, Humanities and Social Sciences Theses

This dissertation examines how the Marine Corps, as a newly formed permanent force, understood and embodied key social ideals such as honour and trustworthiness, respect and deference alongside martial behaviours. It uncovers and analyses the self-sanctioning nature of the marines’ officer corps to impose conforming behaviours during this key period in the Marine Corps’ development. However, this dissertation is equally interested in the non-commissioned and enlisted ranks, and their responses to the imposed conformity to these values. These early cases, linked to ideal behaviour, show a form of self-fashioning as the men of the Corps sought to form their identity …

George Morland (1763-1804) And The Representation Of Social Types, Heather Yeomans

School of Law, Humanities and Social Sciences Theses

George Morland was an eighteenth century artist, who was very popular not only during his lifetime, but in the following hundred years as well. He then fell out of popularity after changes in fashion and trends following the First World War. His paintings contain scenes of rural communities, families, animals, travellers, seaside communities as well as the slave trade, they cover a wide range of eighteenth century social types. Morland lived a ‘bohemian’ lifestyle which allowed him to get to know the people he depicted, living within the communities. His paintings have been analysed in detail in only a few …

The Current State Of South-West Rural Representation In Contemporary Theatre., Ryan Wilce

School of Law, Humanities and Social Sciences Theses

The following thesis will present the current state of South-West rural representation in contemporary theatre and explore who has the right to tell rural communities stories. Using rural proofing as a base framework will present a new framework for theatre makers to inform and influence their creative representations of South-West rural life. To understand the current state of representation and create the framework to improve this, I will be using formalist, actantial and script analysis of select plays, practitioners and theatre companies representing rural life in their work. Equally, my work as a theatre maker will be analysed as I …

Assessing National Progress Of Mediterranean Countries In Shark Governance In The Context Of International Legal Obligations, Lydia Koehler

School of Law, Humanities and Social Sciences Theses

The work presented in this thesis introduces a conceptual framework for shark policy making against which national progress of Mediterranean coastal States in shark governance was assessed. A detailed assessment strategy was developed based on three distinct constructs, namely political commitment, research, and implementation effort. Based on multiple data sources (national reports under relevant conventions; policy documents; national legislation; online databases; scientific literature; and survey questionnaires to relevant government bodies, non-governmental organisations (NGOs), and national experts, designed as part of this assessment), individual differences between countries were determined and evaluated within the context of legal requirements under international and regional …

Speculations On Force And Form: Resisting The Neurotypical In The Neoliberal University, Helen Bowstead

School of Law, Humanities and Social Sciences Theses

Can reframing a thesis in terms of what it can do rather than what it is generate a joyful-artful engagement with the PhD process and engender a more response-able relationship with the world? In this tentative exemplification of the speculative potential of force and form, the very act of writing emerges as a powerful antidote to constraints of the neoliberal university. Exploring writing as immanent doing, Erin Manning’s philosophical projects of research-creation, artfulness and thought in motion find expression through the ordinary, the everyday and the mundane. By refusing to engage in the dis-abling constraints prescribed by institutional expectations of …

Gene-Educational Attainment Interactions In A Multi-Population Genome-Wide Meta-Analysis Identify Novel Lipid Loci, Lisa De Las Fuentes, Karen L. Schwander, Yun Ju Sung, Mary F. Feitosa, Ahn Do, C. Charles Gu, Treva K. Rice, Mary K. Wojczynski, Michael M. Province, Dabeeru C. Rao, Et Al.

2020-Current year OA Pubs

No abstract provided.

My Auschwitz State Of Mind: A Study Of The Nature Of Emergence Of A Text In Relation To Auschwitz, Ivan Alexander Pope

School of Law, Humanities and Social Sciences Theses

This thesis uses practice-based research to ask how I can write a textual deep map from an investigation of Auschwitz-Birkenau. As a key part of the research, I made repeated visits to the environs of Auschwitz-Birkenau, walking and cycling extensively around the area in a search for contemporary fragments in the landscape, for example buildings, routes, sites, landmarks, place names, signposts and found objects. I used my own collection of guides, documents, textual, cartographic and photographic fragments and other ephemera related to the town and the Auschwitz museum in addition to support from the Auschwitz Museum itself and external archives …

Towards Quantum Computing For Audio And Music Expression, Paulo Vitor Itaboraí

School of Law, Humanities and Social Sciences Theses

This research delves into the initial approaches of the use of emerging Quantum Computing technologies in music practice, anchored on preliminary studies on Quantum Representation of Audio (QRA). The approach is interdisciplinary, and attempts to explore the object - QRA - both from a technical scope and an artistic scope. A systematic review unifies diverse QRA techniques, spotlighting the need to bring accessibility to these techniques and terminologies (dense in theoretical physics formalism) for a computer music and/or artistic audiences, in a didactic manner. In this review, some additional techniques initially only discussed for representing images are translated into audio. …

What Can State Medical Boards Do To Effectively Address Serious Ethical Violations?, Tristan Mcintosh, Elizabeth Pendo, Heidi A Walsh, Kari A Baldwin, Patricia King, Emily E Anderson, Catherine V Caldicott, Jeffrey D Carter, Sandra H Johnson, Katherine Mathews, William A Norcross, Dana C Shaffer, James M Dubois

2020-Current year OA Pubs

State Medical Boards (SMBs) can take severe disciplinary actions (e.g., license revocation or suspension) against physicians who commit egregious wrongdoing in order to protect the public. However, there is noteworthy variability in the extent to which SMBs impose severe disciplinary action. In this manuscript, we present and synthesize a subset of 11 recommendations based on findings from our team's larger consensus-building project that identified a list of 56 policies and legal provisions SMBs can use to better protect patients from egregious wrongdoing by physicians.

A Chronicle Of Place: Three Novellas And A Critical Dissertation On Compositional Process With A Contextual Analysis Of Annie Proulx's 'Barkskins' And Michael Cunningham's 'The Hours', Helen Chamberlain

School of Law, Humanities and Social Sciences Theses

This thesis is presented in two parts: a work of fiction in the form of three interconnected novellas exploring settler colonialism of Native north-east America (New England), with a critical dissertation as supplement. The research encompasses four main areas: archival; contextual; experiential and the primary field of practice research. Of particular importance to the research was field work conducted in the U.S., which included meetings with Wampanoag educators and artists, and interviews and archival research at the Plimoth Patuxet Museum. The research has been informed by the work of several writers, both historical and contemporary. Primary and secondary historical sources …

Alterity In Central And Eastern European Illustrations For The Lord Of The Rings 1981-1993, Joel Merriner

School of Law, Humanities and Social Sciences Theses

The 2001-2003 cinematic release of Peter Jackson’s movie adaptation of J.R.R. Tolkien’s The Lord of the Rings heralded a period of widespread pictorial homogenisation in Tolkien visual culture. Propelled by the conceptual design of veteran “Western” Tolkien artists Alan Lee and John Howe, Jackson’s vision of Middle-earth became the hegemonic model by which other depictions are measured. Consequently, the potential for undertaking a scholarly examination of an alternative, specifically non-Western Tolkien vision (with all the implications for visual difference and/or commonality this might involve), has been largely ignored. This dissertation, however, seeks to foster a deeper understanding of the possibility …

A Sage And A Guru Walk Into A Bar: Wisdom And Humor Styles, Jeffrey Dean Webster, Sonja Heintz

School of Psychology

Two studies investigated the relationship between wisdom, humor styles, comic styles, and wellbeing. In Study 1, 325 English-speaking college students completed the Self-Assessed Wisdom Scale (SAWS) and the Humor Styles Questionnaire. As predicted, overall wisdom, as well as all five wisdom subscales, was positively correlated with adaptive humor styles. Furthermore, the SAWS humor subscale correlated positively with all humor styles, most strongly with the adaptive styles. In Study 2, 189 German-speaking university students and adults from the general population completed the SAWS, the Comic Style Markers, and measures of positive mental health (meaning in life, optimism, and resilience). The SAWS …

Do You See What I See?: Testing Horses' Ability To Recognise Real-Life Objects From 2d Computer Projections, S Kappel, Marm De Oca, S Collins, K Herborn, M Mendl, C Fureix

School of Biological and Marine Sciences

No abstract provided.

Post-Covid Syndrome And Adults With Intellectual Disability: Another Vulnerable Population Forgotten?, R Shankar, B Perera, A Roy, Et Al

Peninsula Medical School

An area of interest presently is the lingering symptoms after COVID-19, i.e. post-COVID-19 syndrome (PCS). Specifics of diagnosis and management of PCS are emerging. However, vulnerable populations such as those with intellectual disabilities, who were disproportionately affected by the pandemic, risk being ‘left behind’ from these considerations.

Spatial And Seasonal Variations In Dissolved Methane Across A Large Lake, Mike Peacock, Scott J. Davidson, Dolly N. Kothawala, Joel Segersten, Martyn N. Futter

School of Geography, Earth and Environmental Sciences

Lakes process large volumes of organic carbon (OC), are important sources of methane (CH4), and contribute to climatic warming. However, there is a lack of data from large lakes >500 km2, which creates uncertainty in global budgets. In this data article, we present dissolved CH4, OC bioreactivity measurements, water chemistry, and algal biovolumes at 11 stations across Lake Mälaren, the third largest (1,074 km2) Swedish lake. Total phosphorus concentrations show that during the study period the lake was classed as mesotrophic/eutrophic. Overall mean CH4 concentration from all stations, sampled five times to cover seasonal variation, was 2.51 μg l−1 (0.98–5.39 …

Frontal Variant Alzheimer's Disease: A Systematic Narrative Synthesis, Sarah Salo

School of Psychology

BackgroundFrontal variant Alzheimer's disease (fvAD) is considered a rare form of Alzheimer's disease (AD) which may be misdiagnosed as behavioural variant frontotemporal dementia (bvFTD). The literature has tended to conflate behavioural and executive dysfunction in fvAD cohorts and uses both AD diagnostic criteria and bvFTD diagnostic criteria to classify fvAD cohorts. The primary aim of this narrative synthesis was to summarise neuropsychological findings in fvAD cohorts in the context of established AD pathology.MethodsEMBASE, PsycINFO, PROQUEST and MEDLINE databases were searched for studies eligible for inclusion. Studies with both neuropsychological and biomarker evidence were included in the final narrative synthesis.ResultsTen studies …

How To … Define Clinical Education Research Terminology: A Glossary, Gabrielle M. Finn, Ben Charmer, Oliver E. Burton, Aqua Asif, Matthew H.V. Byrne, Nicola Brennan, Megan E.L. Brown

Peninsula Medical School

Clinical education research (ClinEdR) utilises diverse terminology, which can lead to confusion. A common language is essential for enhancing impact. An expert panel drawn from various workstreams within the National Institute for Health and Care Research (NIHR) Incubator for Clinical Education Research was tasked with reviewing an initial list of terms for the development of a glossary of terms in the field of ClinEdR. The glossary was populated with terms, definitions and foundational papers by the authors and peer-reviewed for accuracy. The glossary of terms developed for ClinEdR should enable researchers to use a common language, promoting consistency and improving …

Severe Central Nervous System Demyelination In Sanfilippo Disease, Mahsa Taherzadeh, Erjun Zhang, Irene Londono, Benjamin De Leener, Sophie Wang, Jonathan D Cooper, Timothy E Kennedy, Carlos R Morales, Zesheng Chen, Gregory A Lodygensky, Alexey V Pshezhetsky

2020-Current year OA Pubs

INTRODUCTION: Chronic progressive neuroinflammation is a hallmark of neurological lysosomal storage diseases, including mucopolysaccharidosis III (MPS III or Sanfilippo disease). Since neuroinflammation is linked to white matter tract pathology, we analyzed axonal myelination and white matter density in the mouse model of MPS IIIC

METHODS: Brain and spinal cord tissues of human MPS III patients, 6-month-old

RESULTS: Analyses of CC and spinal cord tissues by immunohistochemistry revealed substantially reduced levels of myelin-associated proteins including Myelin Basic Protein, Myelin Associated Glycoprotein, and Myelin Oligodendrocyte Glycoprotein. Furthermore, ultrastructural analyses revealed disruption of myelin sheath organization and reduced myelin thickness in the brains …

Identifying Core Components Of A Radiotherapy Comfort Intervention Package Using Nominal Group Technique Radiography, S. Goldsworthy, J.M. Latour, S. Palmer, H. Mcnair, M. Cramp

School of Nursing and Midwifery

Introduction A comfortable treatment position in radiotherapy may promote patient stability and improve outcomes such as accuracy. The aim of this study was to identify, prioritise and determine the feasibility of delivery of intervention components as part of a radiotherapy comfort intervention package. Methods Prior research, consisting of a systematic review and qualitative interviews with patient and therapeutic radiographers, was triangulated and 15 intervention components developed. An online nominal group technique consensus meeting with 7 patients who received radiotherapy exceeding 10 min for one of three anatomical cancer sites and 3 therapeutic radiographers (TRs) participated. Four activities were undertaken: 1) …

Defining Solute Carrier Transporter Signatures Of Murine Immune Cell Subsets, Tania Løve Aaes, Javier Burgoa Cardás, Kodi S Ravichandran

2020-Current year OA Pubs

Solute carrier (SLC) transporters are membrane-bound proteins that facilitate nutrient transport, and the movement across cellular membranes of various substrates ranging from ions to amino acids, metabolites and drugs. Recently, SLCs have gained increased attention due to their functional linkage to innate immunological processes such as the clearance of dead cells and anti-microbial defense. Further, the druggable nature of these transporters provides unique opportunities for improving outcomes in different immunological diseases. Although the SLCs represent the largest group of transporters and are often identified as significant hits in omics data sets, their role in immunology has been insufficiently explored. This …

Measuring The Effectiveness Of Using Rangers To Deliver A Behavior Change Campaign On Sustainable Palm Oil In A Uk Zoo, Katie Major, Daniel Smith

School of Psychology

A fundamental objective of modern zoos is promoting pro-environmental behaviors. This study experimentally assessed the contribution of zoo rangers (staff employed to engage visitors) in delivering a behavior change campaign promoting sustainable palm oil use. The campaign was delivered in a dedicated area in a walk-through animal exhibit, with rangers either “present” or “absent” in the campaign space. Questionnaires assessing awareness, knowledge, and purchasing intentions were completed by 1032 visitors. Two analyses were conducted: (1) comparing the impact of ranger presence versus absence (to assess the overall impact of having rangers present regardless of whether they talked to visitors) and …

The Microbiomes Of Wildlife And Chemical Pollution: Status, Knowledge Gaps And Challenges, R. D. Handy, N. J. Clark, L. P. Hutt, R. Bescós

School of Biological and Marine Sciences

The effect of chemical pollution on the microbiomes of wildlife has been given little attention. A new concept is emerging where microbiomes are vital to host animal or plant health, and for ecosystems. Data are mainly on mammals, birds, and fish. Changing environmental conditions (e.g., salinity, pH, season) and exposure to chemicals alter the composition of gill, gut and skin microbiomes. Gut microbiomes are also modulated by diet, and exposure to chemicals including metals, nanomaterials, fungicides or microplastics. However, a change in the microbiome does not necessarily infer adverse effects on the host, with some evidence of co-adaptation. Environmental risk …