Digital Commons Network^™

Impact Of A Nutrient Formulation On Longitudinal Myelination, Cognition, And Behavior From Birth To 2 Years: A Randomized Clinical Trial, Nora Schneider, Mickaël Hartweg, Jonathan O’Regan, Jennifer Beauchemin, Leanne Redman, Daniel S. Hsia, Pascal Steiner, Owen Carmichael, Viren D’Sa, Sean Deoni

Clinical Research Faculty Publications

Observation studies suggest differences in myelination in relation to differences in early life nutrition. This two-center randomized controlled trial investigates the effect of a 12-month nutritional intervention on longitudinal changes in myelination, cognition, and behavior. Eighty-one full-term, neurotypical infants were randomized into an investigational (N = 42) or a control group (N = 39), receiving higher versus lower levels of a blend of nutrients. Non-randomized breastfed infants (N = 108) served as a reference group. Main outcomes were myelination (MRI), neurodevelopment (Bayley-III), social-emotional development (ASQ:SE-2), infant and toddler behavior (IBQ-R and TBAQ), and infant sleep (BISQ) during the first 2 …

Sexually Dimorphic Oxytocin Receptor-Expressing (Oxtr) Neurons In The Anteroventral Periventricular Nucleus (Avpv) In The Postpartum Female Mouse Are Involved In Maternal Behavior, Kaustubh Sharma, Armita A. Govar, Bandana Ghimire, Katsuhiko Nishimori, Elizabeth Hammock, Ryoichi Teruyama

Faculty Publications

Maternal care is crucial for the survival and development of offspring. Oxytocin modulates maternal behavior by binding to oxytocin receptors (OXTRs) in various parts of the brain. Previously, we showed that OXTRs are expressed in the anteroventral periventricular nucleus (AVPV) of female, but not male mice. Because the AVPV is involved in the regulation of maternal behavior and oxytocin enhances its induction, this finding leads to the hypothesis that the female specific population of OXTR neurons in the AVPV regulates maternal behavior. To address this hypothesis, OXTR-Venus reporter mice were used to assess if expression levels of OXTR in the …

Beyond The Classroom Volume 07 October 2023 - Hearts, Minds, Welfare, Hope, Students Affairs And Services, Pakistan

Student Affairs and Services (SAS) - Beyond the Classroom Archives

• Hearts, Minds, Welfare, Hope
• Spotlight - Aurora
• Spotlight - Falah
• Featured Story - WMHD2023|Walk-A-Cause
• Featured Story - WMHD2023|Panel Discussions
• Featured Story - WMHD2023|Mandala Activity
• Featured Story - Falah Carnival
• Featured Story - Bakesale Fundraiser
• Antakshari Night
• Students Win Unilever Challenge
• World Heart Day Bikeathon
• Manuscript Writing Session

2023 Fall Nutshell, Morehead State University. Institutional Research & Analysis.

Office of Institutional Research & Analysis Publication Archive

Fall 2023 issue of the Nutshell.

2023-10-01 Caudill Connection, Morehead State University. Caudill College Of Arts, Humanities And Social Sciences.

Caudill Connection

Caudill Connection newsletter for October of 2023.

Salary Report, 2023 October, Eastern Michigan University

EMU Salary Reports

No abstract provided.

George C. Caldwell (1834-1907): American Agricultural Chemist, Pat Munday

Interdisciplinary Arts and Sciences Articles

George Caldwell served as president of the American Chemical Society (ACS) in 1892. Prior to this time, the ACS had been a rather parochial New York City based organization. In 1890, the constituency of the ACS expressed its desire to become a truly national body. Toward this end, it forged closer ties with the Chemical Section of the American Association for the Advancement of Science (AAAS), and merged with the Chemical Section in 1891. As Caldwell had been active with the AAAS group for several years previous to this merger, his election to the presidency of the ACS can be …

Pubertal Progression And Its Relationship To Psychological And Behavioral Outcomes Among Adolescent Boys, Meng-Che Tsai, Yu-Chung Lawrence Wang, Hsun-Yu Chan

Faculty Publications

Variations in pubertal timing and tempo have relevance to psychosocial development. Accounting for pubertal timing, tempo, and psychosocial development simultaneously in a model remains challenging. This study aimed to document the typology of pubertal development in a cohort of Taiwanese adolescent boys and then to examine how the associations between psychosocial variables across time vary by the patterns of pubertal development. A group of adolescent boys (n = 1,368) reported pubertal signs and psychosocial variables for 3 years since seventh grade. The growth mixture model revealed three major classes of pubertal transition: average pubertal growth, late-onset with rapid catch-up, and …

Fall 2023, Seattle University

Seattle University Magazine

No abstract provided.

Amazon's Pricing Paradox, Rory Van Loo, Nikita Aggarwal

Articles

Antitrust scholars have widely debated the paradox of Amazon seemingly wielding monopoly power while charging low prices to consumers. A single company's behavior thereby helped spark a vibrant intellectual conversation as scholars debated why Amazon's prices were so low, whether enforcers should intervene, and, eventually, how the field of antitrust should be reformed. One of the main sources of agreement in these and other scholarly conversations has long been that Amazon charges low prices. This Article challenges that assumption by demonstrating that Amazon customers may pay significantly higher prices than is commonly understood due to strategies that do not necessarily …

Information Literacy Curriculum Mapping In The Health Sciences, Devon Olson, Sandi Bates, Shannon Yarbrough, Sara Westall, Megan Keely Carroll Denis, Montanna Barnett

Librarian Publications

Instructional medical librarians are uniquely positioned in a context governed by multiple instructional frameworks emerging from librarianship and the professions with which they liaise. Yet very little literature exists on medical librarians’ use of curriculum mapping to align their instruction with these frameworks. This review illuminates the current state of curriculum mapping in medical librarianship.We searched five bibliographic databases for articles published between 2010 and August 2021 and centred on information literacy(IL)curriculum mapping within a health sciences university context. Studies were included based upon pre-determined inclusion and exclusion criteria. Data were extracted using an instrument developed primarily a priori, with …

Trauma-Informed Policing: The Impact Of Adult And Childhood Trauma On Law Enforcement Officers, André Douglas Pond Cummings, Todd J. Clark, Caleb Gregory Conrad, Honorable Amy Dunn Johnson

Law Faculty Scholarship

For every six months that a police officer serves in the line of duty, he or she is likely to experience an average of three traumatic events. Such events may include fatal accidents, murders, suicides, and active threats to the life of the officer or someone else. Given the wealth of available data on how trauma reorganizes the nervous system to respond to everyday stimuli as threatening, this is an area that cries for critical exploration, especially in light of the frequency with which unarmed Black civilians are killed at the hands of officers who often make split-second decisions to …

A Song Of Ice And Feathers: The Bioacoustics Of Adélie Penguin Colonies, William Brandenburg

Inquiry Journal Fall 2023

Using data collected in Antarctica, William examined the bioacoustics of a valuable indicator species of climate change.

Loggerhead Shrike Occurrence Along Urban Gradients In South Carolina’S Coastal Plain, Michelle A. Krauser, Christopher E. Hill

Biology

The urban landscape is understudied compared to less developed ecosystems, despite providing suitable habitat for wildlife, including some species of grassland birds. Loggerhead Shrikes (Lanius ludovicianus) are predatory songbirds that frequent grasslands and have been observed using grassy areas in developed and more natural landscapes, yet remain largely unstudied in developed landscapes. We investigated the effects of development, measured as impervious surface percentage, on Loggerhead Shrike occurrence in urban areas in South Carolina, U.S.A, and also tracked canopy cover (%), highway density (m/ha), non-highway road density (m/ha), total road density (m/ha), and powerline density (m/ha). The first author searched 300 …

El Leñador, October 2023, El Leñador Staff

El Leñador Newspaper

El Leñador is an English and Spanish newspaper produced by Humboldt State University students. Our staff cover and provide news to Latinx and other diverse communities on campus and in Humboldt County. We are committed to providing relevant news and expanding the representations and stories told about people of color and other marginalized groups. Our work helps create more social, political and cultural diversity in local media.

El Leñador es un periodico en español y inglés producido por estudiantes de la Universidad Estatal de Humboldt. Nuestro personal cubre y provee noticias a la comunidad Latinx y otras comunidades diversas en …

A Democratic Perspective On Tax Law, Clint Wallace

Washington Law Review

As democracies around the world have faltered, legal scholars in fields as diverse as election law, labor law, and administrative law have turned to tax law to repair and support democratic governments. Taxation offers a toolset well-equipped to address concerns raised by democratic theorists focused on the conditions that shape a democratic community and help it to flourish. Tax laws can rectify social dynamics characterized by economic inequality and can help establish and strengthen civic institutions, among many possible interventions. But legal scholars evaluating and designing tax policies generally focus on the standard normative criteria of efficiency, equity, and administrability, …

Connecting Fragmented Support On Campus: Growing Research Data Services Programs Through Collaboration, Patricia B. Condon, Thea P. Atwood, Catherine Derose

Collaborative Librarianship

Research data services are provided by multiple units across and beyond the library, which is why communication and collaboration are paramount to building support for researchers. By exploring how Research Data Services (RDS) programs can function in the fragmented landscape of research support on campuses, we outline the role of collaboration in building programs. In this paper, we discuss building an RDS program by emphasizing three strategies for collaboration: collaborating within the library, collaborating across campus, and collaborating externally with those without direct ties to your organization. The aim of this paper is to offer attainable examples and strategies for …

Brilliant Bird Brains: Object Recognition In Herring Gulls (Larus Argentatus Smithsonianus), Kristen M. Covino, F. Dylan Titmuss, Joseph E. Brosseau, Dora C. Donacik, Maddie E. Ellms, Alyssa R. Nowicki, Daphne Okuyama, Jessica M. Robinson, Katherine A. Schickfus, Eliza L. Stanley, Mary Elizabeth Everett

Biology Faculty Works

The ability to recognize and associate objects with prior experiences has been demonstrated in several avian taxa. Corvids, for example, recognize visual stimuli associated with negative previous experiences and will modify their behavioral responses according to the level of perceived threat. However, the extent to which similar memory-based behaviors exist in seabirds is poorly understood. Our study investigated object recognition by Herring Gulls (Larus argentatus smithsonianus) on their breeding grounds, the site of a long-term monitoring project. When handling gulls and conducting field research, researchers wear standard bicycle helmets as a protective measure against physical aggression by nesting …

Genomic Approaches To Mitigating Genetic Diversity Loss In Declining Populations, Christen M. Bossu, Marina Rodriguez, Christine Rayne, Debra A. Chromczak, Philip G. Higgins, Lynne A. Trulio, Kristen C. Ruegg

Faculty Research, Scholarly, and Creative Activity

The accelerating pace of global biodiversity loss is exacerbated by habitat fragmentation and subsequent inbreeding in small populations. To address this problem, conservation practitioners often turn to assisted breeding programmes with the aim of enhancing genetic diversity in declining populations. Although genomic information is infrequently included in these efforts, it has the potential to significantly enhance the success of such programmes. In this study, we showcase the value of genomic approaches for increasing genetic diversity in assisted breeding efforts, specifically focusing on a highly inbred population of Western burrowing owls. To maximize genetic diversity in the resulting offspring, we begin …

Public Defenders As Gatekeepers Of Freedom, Alma Magaña

Articles

Nearly half a million people are currently held in pretrial detention across the United States. Legal scholarship has explored many of the actors and factors contributing to the deprivation of freedom of those presumed innocent. And while the scholarship in these areas is rich, it has primarily focused on certain system actors—including judges, prosecutors, and profit-seeking sheriffs—structural concerns, such as the role race plays in who is being held in pretrial detention, or critiques of the failed promise of algorithms to deliver on bias-free bail determinations. But relatively little scholarship exists about the contributions of public defenders to this deprivation. …

The Effect Of Microlearning And Multimedia Design On Knowledge And Skills Acquisition Of Students In E-Courses, Rene Corbeil, Didem Tufan, Maria Elena Corbeil

Teaching and Learning Faculty Publications

Although the term microlearning has been around since 2005 (Hug, 2005), its use, and research in the area, have resurged in recent years as adult learners have become increasingly more mobile and must deal with competing work, family, and educational priorities. Today’s learners, in both formal and informal academic and corporate learning environments, can benefit from microlearning’s smaller, single objective lessons that can be consumed quickly and easily. However, there are many variations of microlearning and ideas on how to create the instructional materials they include. While it may seem simple, the development process requires applying instructional design strategies and …

Amazon's Pricing Paradox, Rory Van Loo, Nikita Aggarwal

Faculty Scholarship

Antitrust scholars have widely debated the apparent paradox of Amazon seemingly wielding monopoly power while offering low prices to consumers. A single company’s behavior thereby helped spark an intellectual renaissance as scholars debated why Amazon’s prices were so low, whether antitrust enforcers should intervene, and, eventually, how the field should be reformed for the era of large online platforms. One of the few things that all parties have agreed upon amidst those contentious conversations is that Amazon offers low prices. This Article challenges that assumption by demonstrating that Amazon charges higher prices than commonly understood. More importantly, unraveling the disconnect …

Editorial: An Unexpected Event Related To The Aquatic Mammals Of Latin America, Daniel Gonzalez-Socoloske

Faculty Publications

No abstract provided.

The Vcam1-Apoe Pathway Directs Microglial Chemotaxis And Alleviates Alzheimer's Disease Pathology, Shun-Fat Lau, Wei Wu, Hiu Yi Wong, Li Ouyang, Yi Qiao, Jiahui Xu, Jessica Hiu-Yan Lau, Carlton Wong, Yuanbing Jiang, David M Holtzman, Amy K Y Fu, Nancy Y Ip

2020-Current year OA Pubs

In Alzheimer's disease (AD), sensome receptor dysfunction impairs microglial danger-associated molecular pattern (DAMP) clearance and exacerbates disease pathology. Although extrinsic signals, including interleukin-33 (IL-33), can restore microglial DAMP clearance, it remains largely unclear how the sensome receptor is regulated and interacts with DAMP during phagocytic clearance. Here, we show that IL-33 induces VCAM1 in microglia, which promotes microglial chemotaxis toward amyloid-beta (Aβ) plaque-associated ApoE, and leads to Aβ clearance. We show that IL-33 stimulates a chemotactic state in microglia, characterized by Aβ-directed migration. Functional screening identified that VCAM1 directs microglial Aβ chemotaxis by sensing Aβ plaque-associated ApoE. Moreover, we found …

Dmrt1 Regulates Human Germline Commitment, Naoko Irie, Sun-Min Lee, Valentina Lorenzi, Haiqi Xu, Jinfeng Chen, Masato Inoue, Toshihiro Kobayashi, Carmen Sancho-Serra, Elena Drousioti, Sabine Dietmann, Roser Vento-Tormo, Chun-Xiao Song, M Azim Surani

2020-Current year OA Pubs

Germline commitment following primordial germ cell (PGC) specification during early human development establishes an epigenetic programme and competence for gametogenesis. Here we follow the progression of nascent PGC-like cells derived from human embryonic stem cells in vitro. We show that switching from BMP signalling for PGC specification to Activin A and retinoic acid resulted in DMRT1 and CDH5 expression, the indicators of migratory PGCs in vivo. Moreover, the induction of DMRT1 and SOX17 in PGC-like cells promoted epigenetic resetting with striking global enrichment of 5-hydroxymethylcytosine and locus-specific loss of 5-methylcytosine at DMRT1 binding sites and the expression of DAZL representing …

Clinical Classification Of Variants In The Valosin-Containing Protein Gene Associated With Multisystem Proteinopathy, Marianela Schiava, Jil Daw, Conrad Chris Weihl, Et Al.

2020-Current year OA Pubs

BACKGROUND AND OBJECTIVES: Pathogenic variants in the valosin-containing protein (

METHODS: A 6-item clinical score was developed to evaluate the phenotypic level of evidence to support the pathogenicity of the novel variants. Each item is allocated a value, a score ranging from 0.5 to 5.5 points. A receiver-operating characteristic curve was used to identify a cutoff value of 3 to consider a variant as high likelihood disease associated. The scoring system results were confronted with results of in vitro ATPase activity assays and with in silico analysis.

RESULTS: All variants were missense, except for one small deletion-insertion, 18 led to …

Social And Biological Perspectives To Investigate And Address Illegal Shooting Of Raptors, Eve Thomason, Kenneth Wallen, Todd Katzner

Raptor Research Center Publications and Presentations

Humans have shot raptors for centuries. However, in many countries these actions have been illegal since the mid-twentieth century. Despite this history, there is not a comprehensive understanding of the characteristics of this activity, its frequency, and why it occurs. We used literature review and principles drawn from ecology, sociology, and criminology to understand this problem. First, we review literature on raptor shooting globally to explore documented motivations for shooting and we describe the history of raptor shooting in the United States of America (USA). Then, to illustrate the contemporary frequency and geographic breadth of the shooting of raptors, we …

What's Not Natural Phenomena? Let's Consider A Three-Step Innovative Concept Test For Composition Of Matter Claims, Sydney Hancock

IP Theory

Biotechnology innovation is rapidly growing, especially in the realm of biotech. This growth leads to questions about patent subject matter eligibility of natural phenomena. For example, currently the human genome and microbiome are being extensively studied, bacteriophages are being edited, animals are being cloned, and CRISPR is widespread. Additionally, composition of matter patent claims give the most protection to patent holders. Therefore, knowing when a natural phenomenon veers into human innovation is important for courts, lawyers, and innovators in the era of biotechnology and genetic engineering.

Part I discusses the history of Supreme Court cases on natural phenomena subject matter …

Association Of Prolactin With All-Cause And Cardiovascular Mortality Among Patients With Type 2 Diabetes: A Real-World Study, Yun Shen, Qing Yang, Tingting Hu, Yaxin Wang, Lei Chen, Fei Gao, Wei Zhu, Gang Hu, Jian Zhou, Chunfang Wang, Yuqian Bao

Population and Public Health Science Faculty Publications

Aims The association between prolactin and mortality has been less studied, and findings were inconsistent among different populations. We aimed to investigate the association between serum prolactin (PRL) and mortality among patients with type 2 diabetes. Methods We performed a retrospective cohort study of 10 907 patients with at least 2 prolactin measurements within 2 years since and results their first inpatient diagnosis of type 2 diabetes. Baseline and mean values of serum PRL were used as exposures. A multivariable-adjusted Cox proportional hazards model was used to estimate the association between PRL and mortality. During a mean follow-up of 5.34 …

Zora Neale Hurston: Claiming A Space, Judith E. Smith

American Studies Faculty Publication Series

No abstract provided.