Digital Commons Network^™

Artist Spotlight, Rosalba Breazeale

Hemisphere: Visual Cultures of the Americas

No abstract provided.

Hemisphere: Visual Cultures Of The Americas Volume Xv, 2023

Hemisphere: Visual Cultures of the Americas

No abstract provided.

Cell Surface And Plasma Biomarkers Of Kaposi Sarcoma, Sara R. Privatt

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Kaposi sarcoma-associated herpesvirus is the etiological agent of several pathologies including Kaposi sarcoma, primary effusion lymphoma, and multicentric Castleman’s disease. Here, we investigated both the tumor microenvironment (TME) in KS lesions as well as plasma from KSHV-infected individuals and how metabolic dysfunction and dysregulated cytokines might have a systemic effect on KS tumorigenesis. Based on previously published KS tumor transcriptomics, one aspect of our investigation involved characterizing cell surface glycoproteins with potential to serve as therapeutic targets against KSHV-infected cells or KS tumors or as biomarkers for disease. Expression patterns of such markers may also suggest the cellular origin of …

Precipitation And Greenness In Pastoral Lands Of East Turkana, Kenya, Paul Akpejeluh

School of Natural Resources: Dissertations, Theses, and Student Research

Pastoralism has long supported livelihoods and provided essential ecosystem services in landscapes of East Africa. Vegetation productivity is central to the functioning of pastoral systems but may be affected by changes in climate and landuse. Vegetation monitoring is important for understanding the effects of global change in pastoral lands; however, it can be time and resource intensive. Remote sensing provides opportunities for efficient multi-scale monitoring of vegetation and climatic drivers. In this thesis, I explore the utility of satellite and UAV remote sensing for monitoring vegetation and precipitation trends and relationships in the East of Lake Turkana Region of northern …

Connecting The Nebraska Water Quality Index To The Aquatic Microbial Community Of The North Platte River Basin, Nebraska, Paula R. Guastello

School of Natural Resources: Dissertations, Theses, and Student Research

The Nebraska Water Quality Index, under development by the Nebraska Department of Environment and Energy, summarizes in a single value eight environmental parameters that have been monitored in Nebraska for nearly 20 years. Water quality parameters including those used in the Nebraska Water Quality Index have been shown in previous studies to impact bacterial growth. As such, this index has the potential to correlate with the freshwater microbial community. Here, I relate the Nebraska Water Quality Index to microbial community composition and structure using 16S rRNA gene amplicon sequence data collected from the North Platte River Basin, Nebraska. This index …

Discursive Struggles Reflected In The Communication Of Conservative Christian Parents And Their Adult Children With Differing Religious Beliefs And Values, Braedon G. Worman

Department of Communication Studies: Dissertations, Theses, and Student Research

Nearly half of American adults no longer believe in their childhood faiths (Pew Research Center, 2015). The steady decline of Christianity could have considerable impacts on family life (Pew Research Center, 2022). From a postmodern critical perspective and guided by Relational Dialectics Theory 2.0, the researcher sought to discern how conservative Christian parents and their adult children with differing religious beliefs and values communicated when they discussed these differences, as well as to identify the discourses that informed and were reflected in their talk and illustrate how these discourses interplayed and animated the meaning of participants’ Christian family identities. The …

Off The Rails: Cinematic Trains As Technological Controls Of The Natural World, Trinity Thompson

Honors Program: Senior Projects (Public)

Short train rail lines across the United States are seeing increased national funding to reduce toxic chemical spills caused by train derailments, the most notable of which happened in February 2023 in East Palestine, Ohio. A year prior, the film White Noise (2022) featured a similar toxic train derailment incident, taking place, too, in Eastern Ohio, and featuring actors from the town of East Palestine. In considering other films featuring trains, I identified a pattern of environmental conflict, leading me to question the relationship between trains and the natural environment as portrayed in popular cinema. To conduct my research, I …

Furry Friends & Brighter Futures: Enhancing The Life Skills Of Toddlers With Autism Through Animal Assisted Therapy, Abigail Tolentino

Nursing | Student Research Posters

No abstract provided.

Culinary Medicine And The Promotion Of Plant-Based Diets: Is Caution Needed For Older Adults?, Wendy J. Dahl, Sayaka Nagao-Sato, Christina Riccardo

Nutrition Faculty Publications

Culinary Medicine (CM), which combines food, cooking, and the science of medicine1 for the management of chronic disease conditions, is an emerging practice area for health professionals, particularly physicians.2 Culinary skills and food-disease-related knowledge are enhanced by CM training3 ; however, there is much to learn regarding optimal program outcome measures.4 What cannot be gained from a CM program is the comprehensive nutrition knowledge that may be needed to ensure CM prescriptions result in benefits and minimize harm. This may be particularly important for older adults.

Voxelhap: A Toolkit For Constructing Proxies Providing Tactile And Kinesthetic Haptic Feedback In Virtual Reality, M. Feick, C. Biyikli, K. Gani, A. Wittig, Anthony Tang, A. Krüger

Research Collection School Of Computing and Information Systems

Experiencing virtual environments is often limited to abstract interactions with objects. Physical proxies allow users to feel virtual objects, but are often inaccessible. We present the VoxelHap toolkit which enables users to construct highly functional proxy objects using Voxels and Plates. Voxels are blocks with special functionalities that form the core of each physical proxy. Plates increase a proxy’s haptic resolution, such as its shape, texture or weight. Beyond providing physical capabilities to realize haptic sensations, VoxelHap utilizes VR illusion techniques to expand its haptic resolution. We evaluated the capabilities of the VoxelHap toolkit through the construction of a range …

An Amplification-Free Crispr-Sers Biosensor For Specific, Sensitive And Rapid Detection Of Salmonella Typhimurium In Poultry, Fei Jia, Bingyan Li, Yawen He, Yafang Shen, Juhong Chen, Xingmin Li, Yanbin Li

Biological and Agricultural Engineering Faculty Publications and Presentations

CRISPR (Clustered regularly interspaced short palindromic repeats) has been a cutting-edge biotechnology in both gene editing and biosensing due to its desirable features, such as high base resolution and set-and-forget operation. However, as a nucleic acid detection method, an DNA/RNA amplification procedure is still inevitable in CRISPR biosensors. In this study, a highly-ordered nanopore array SERS substrate, coated with silver nanoparticles, was fabricated and utilized as a platform for the specific detection of Salmonella Typhimurium (S. Typhimurium) without the time-consuming DNA amplification step. The smart sensing strategy was established by introducing an ssDNA labeled with a Raman active molecule …

The Federal Circuit’S Experimental Prism, Jeremy W. Bock

Fordham Law Review

Whether the U.S. Court of Appeals for the Federal Circuit is succeeding in its role as the steward of decisional patent law has been the subject of considerable debate and many empirical studies for the past forty years. Based on these studies, some observers have expressed skepticism of the utility of that court’s exclusive, nationwide jurisdiction over patent appeals. But the substantial body of empirical literature on the Federal Circuit has been viewed largely from a single vantage point, one that attributes any negative or undesirable outcomes to the court’s specialization. This Article argues that there is another way to …

Yellowtail Snapper, Abigayle Groth, David Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

No abstract provided.

Interactive Effects Of Increased Nestbox Temperature And Vitamin E On Nestling Growth Are Attenuated By Plasticity In Female Incubation Effort, Paige A. Duncan, Ashley M. Tauber, Scott K. Sakaluk, Charles F. Thompson

Faculty Publications – Biological Sciences

In recent years, temperatures have increased globally, and nestlings of many bird species are likely regularly exposed to increased temperatures both pre- and post-natally. Even small increases in nest temperature during incubation affect offspring growth and survival in a variety of species, one cause of which is thought to be increased production of pro-oxidants in embryos and nestlings. Defences marshalled in response to this oxidative stress could, in turn, result in trade-offs that lead to reduced survival or growth. If so, any downstream negative effects on nestlings of increased ambient temperatures during incubation could be counteracted by increasing their antioxidant …

Web 2 Vs. Web 3 Paths To The Metaverse: Who Is Leading? Who Should Lead?, Le Kuai, Mary Lacity, Jeffrey K. Mullins

Information Systems Faculty Publications and Presentations

Our research investigates two questions: Who is leading the metaverse? Who should lead? The questions are important because metaverse will have significant consequences for individuals, businesses, and society. We examined the current leaders of metaverse on two evolutionary paths, namely Web 2 and Web 3. Based on regulatory reports, corporate press releases, and patents, we found that only a handful of Web 2 companies are “all-in” on metaverse, and at least one of these enterprises, Meta, is on track to end up as a dominant platform provider. Based on market capitalization, user activity, and patents, only a handful of Web …

Design Guidance For Wetland-Road Crossings To Reduce Blanding’S Turtle Mortality Risk, Thomas P. Ballestero, Lauren E. White, Sandra Houghton, David Burdick, Josh Megyesy

Faculty Publications

Road mortality is a leading threat to freshwater turtles, particularly the Blanding’s turtle (Emydoidea blandingii), an endangered species in New Hampshire. Wildlife wetland-crossing structures, such as culverts and/or fences, have proven effective in reducing wildlife road mortality while retaining habitat connectivity. Funding for adequate wetland-crossing creation or restoration is limited, so prioritizing areas of high mortality risk is essential to ensuring that the resources spent are impactful. A research team of professionals from the New Hampshire Department of Environmental Services, New Hampshire Fish and Game, University of New Hampshire, and other organizations formed to create a model capable …

Religious Freedom (For Most) Restoration Act: A Critical Review Of The Ninth Circuit’S Analysis In Apache Stronghold, Alex Mcfarlin

Utah Law Review

This Note analyzes sacred site protection under the Religious Freedom Restoration Act (“RFRA”) and argues that the Ninth Circuit’s upcoming en banc review of Apache Stronghold is a critical moment for many Indigenous faiths. Against the backdrop of a religious freedom resurgence for other faiths over the past decade, the practitioners in Apache Stronghold face the irreparable loss of identity and culture.

Patrolling For Police Disguised As Cultural Experts: California’S Opportunity To Dissolve The Expert Admissibility Double Standard And Restore Due Process, Madison Sykes

University of the Pacific Law Review

No abstract provided.

Enhancing Safety And Security At Colleges And Universities In Tennessee

Miscellaneous Reports

No abstract provided.

The Effect Of A Mn(Iii)Tetrakis(4-Benzoic Acid)Porphyrin (Mntbap) Coating On He Chronic Recording Performance Of Planar Silicon Intracortical Microelectrode Arrays, George F. Hoeferlin, Lindsey N. Druschel, Olivia K. Krebs, Dhariyat M. Menendez, Jonathan L. Duncan, Jichu Zhang, Gaurav Mittal, Jeffrey R. Capadona

Faculty Scholarship

Intracortical microelectrode arrays (MEAs) are used to record neural activity. However, their implantation initiates a neuroinflammatory cascade, involving the accumulation of reactive oxygen species, leading to interface failure. Here, we coated commercially-available MEAs with Mn(III)tetrakis(4-benzoic acid)porphyrin (MnTBAP), to mitigate oxidative stress. First, we assessed the in vitro cytotoxicity of modified sample substrates. Then, we implanted 36 rats with uncoated, MnTBAP-coated (“Coated”), or (3-Aminopropyl)triethoxysilane (APTES)-coated devices – an intermediate step in the coating process. We assessed electrode performance during the acute (1–5 weeks), sub-chronic (6–11 weeks), and chronic (12–16 weeks) phases after implantation. Three subsets of animals were euthanized at different …

Economic Equity And People With Disabilities: Development And Characterization Of A Novel Index, Bhavneet Walia, Katherine Mcdonald, Joy Hammel, Lex Frieden, Michael Morris, Barry Whaley, Vinh Nguyen

Faculty, Staff and Student Publications

Here we develop two new social indices: The ADA PARC Absolute Economic Opportunity Index and the ADA PARC Relative Economic Opportunity Index. These indices allow us novel examinations of economic equity between people with and without disabilities within a U.S. State and between people with disabilities in different states using aggregations of multiple component economic indicators. These represent the first efforts to offer U.S. indices of this focus, an important development given the distinct economic needs of people with disabilities and the value in accounting for distinct national policies. The indices rely on U.S. Census and other data on economic …

Early Skeletal Muscle Loss In Adolescent And Young Adult Cancer Patients Treated With Anthracycline Chemotherapy, Savannah V Wooten, Fei Wang, Michael E Roth, Guanshu Liu, J Andrew Livingston, Behrang Amini, Susan C Gilchrist, Michelle Hildebrandt, Eugenie S Kleinerman

Faculty, Staff and Student Publications

BACKGROUND: Early skeletal muscle loss has been observed in adolescent and young adult (AYA) sarcoma patients undergoing treatment. Identification of individuals within the AYA populace that are at greatest risk of anthracycline-induced skeletal muscle loss is unknown. Moreover, investigations which seek out underlying causes of skeletal muscle degradation during chemotherapy are critical for understanding, preventing, and reducing chronic health conditions associated with poor skeletal muscle status.

METHODS: Computed tomography (CT) scans were used to investigate changes in skeletal muscle of 153 AYA sarcoma and Hodgkin lymphoma patients at thoracic vertebra 4 after anthracycline treatment. Images were examined at three time …

Effect Of The Covid-19 Pandemic On The Epidemiology Of Pediatric Traumatic Brain Injury In Brazil, Leopoldo Mandic Ferreira Furtado, José Aloysio Da Costa Val Filho, Victor Da Silva Pereira, Yasmin S Coimbra, Vitor Hugo R Caldas, Anne R Magalhães, Bruna Athayde S De Carvalho, Saulo G Moreira, Antônio L Teixeira, Aline Silva De Miranda

Faculty, Staff and Student Publications

Aim: In response to the coronavirus 2019 disease (COVID-19) pandemic, governments worldwide implemented measures to prevent infection, resulting in restricted school activities, restricted children’s freedom of movement, and increased risk of violence and injuries at home, including traumatic brain injury (TBI), among children. In Brazil, the consequences of the COVID-19 pandemic on the causes, severity, and mortality of pediatric TBI have not yet been investigated. Thus, our study aimed to determine whether the COVID-19 pandemic has affected the epidemiology of pediatric TBI among Brazilian children.

Materials and methods: We investigated the patients with TBI aged <18 years who visited a tertiary trauma center in Brazil in 2019 and 2020. TBI-related variables, such as classification, mechanism, clinical manifestations, need for intervention, morbidity, and mortality, were recorded. Furthermore, we used a nationwide databank to collect information on mortality from external causes of trauma and violence in the pediatric population in 2019 and 2020. The Mann-Whitney test was used to compare quantitative variables related to the mechanisms and severity of TBI in both periods in order to determine the impact of the COVID-19 pandemic.

Results: Of the patients with …

Wrack Lines Volume 23, No. 2, Fall-Winter 2023-2024, Syma A. Ebbin, Ralph Lewis, Judy Benson, Diana Payne, Miriah Russo Kelly

Wrack Lines

Learn about the inspiring journey of a mini sailboat, lessons from beaches and school aquariums and the unique geology of the Connecticut shoreline in the Fall-Winter 2023-2024 issue of Wrack Lines magazine. More good reading can be found in articles about how the ocean literacy campaign and ocean identity research are working to expand marine science education.

Titled, “Learning about the Sea: How it Becomes Real, Visible and Connecticut to Human Life,” the issue presents the diverse and exciting realm of marine science education, from international excursions to the geologic stories of our coast; from classrooms and beach field trips …

The Effects Of Ethanol Preservation On High-Molecular Weight Dna, Maia Jackson

Honors Capstones

No abstract provided.

Building Urban Sustainability With Quality Elites, Havovi Joshi

Asian Management Insights

Do elites contribute to a society more than they extract from it? In many countries where populism has surged in tandem with declining trust in elites in the political and other spheres, the answer.

Α-Synuclein Is The Major Platelet Isoform But Is Dispensable For Activation, Secretion, And Thrombosis, Alexis N. Smith, Smita Joshi, Harry Chanzu, Hammodah Rawhi Hammodah Alfar, Kanakanagavalli Shravani Prakhya, Sidney W. Whiteheart

Saha Cardiovascular Research Center Faculty Publications

Platelets play many roles in the vasculature ensuring proper hemostasis and maintaining integrity. These roles are facilitated, in part, by cargo molecules released from platelet granules via Soluble NSF Attachment Protein Receptor (SNARE) mediated membrane fusion, which is controlled by several protein-protein interactions. Chaperones have been characterized for t-SNAREs (i.e. Munc18b for Syntaxin-11), but none have been clearly identified for v-SNAREs. α- Synuclein has been proposed as a v-SNARE chaperone which may affect SNARE-complex assembly, fusion pore opening, and thus secretion. Despite its abundance and that it is the only isoform present, α-synuclein’s role in platelet secretion is uncharacterized. In …

Rooted In Meaning: Plant Iconography On Nasca Polychrome Ceramics, Amanda G. Lange

Theses

This thesis explores the Nasca use of plant iconography as part of their polychrome ceramics produced at the end of the Early Horizon around 100 BCE to those produced in the beginning and middle of the Early Intermediate Period circa 1to 450 CE. During this time the religious site of Cahuachi was in use as a pilgrimage center as well as the production center of polychrome pottery. The Nasca created their colorful ceramics here to distribute to visiting pilgrims during times of festival or ritual. The culture’s iconography has been studied extensively, most of which focuses on the forms of …

Shōjo, Kawaii, And Yōkai Iconographies In Chiho Aoshima's Strawberry Fields And How They Relate To Contemporary Gender Dynamics In Japan, Neo Sim Yee

Theses

This paper analyzes the shōjo, kawaii, and yōkai iconographies in Chiho Aoshima’s digital painting Strawberry Fields and examines how they relate to contemporary gender dynamics and anxieties in Japan. The painting bears the artist’s distinctive, characteristic style, which includes elements that are childlike and monstrous, cute and dark. The work, rich in layered context, simultaneously reminisces about the innocence and freedom of adolescence, and critiques the prominent the unequal, rigid, and highly restrictive gender roles dictated by the Japanese patriarchal system. The distinct two halves of Strawberry Fields depict the dichotomous vision of Japanese women—innocent and girly versus defiant and …

Dha Shortage Causes The Early Degeneration Of Photoreceptors And Rpe In Mice With Peroxisomal Β-Oxidation Deficiency, Daniëlle Swinkels, Sai Kocherlakota, Yannick Das, Adriaan D. Dane, Eric J.M. Wever, Frédéric M. Vaz, Nicolas G. Bazan, Paul P. Van Veldhoven, Myriam Baes

School of Medicine Faculty Publications

PURPOSE. Patients deficient in peroxisomal β-oxidation, which is essential for the synthesis of docosahexaenoic acid (DHA, C22:6n-3) and breakdown of very-long-chain polyunsaturated fatty acids (VLC-PUFAs), both important components of photoreceptor outer segments, develop retinopathy present with retinopathy. The representative mouse model lacking the central enzyme of this pathway, multifunctional protein 2 (Mfp2−/−), also show early-onset retinal decay and cell-autonomous retinal pigment epithelium (RPE) degeneration, accompanied by reduced plasma and retinal DHA levels. In this study, we investigated whether DHA supplementation can rescue the retinal degeneration of Mfp2−/− mice. METHODS. Mfp2+/− breeding pairs and their offspring were fed a 0.12% DHA …