Digital Commons Network^™

The Environmental Cellular Stress Response: The Intertidal As A Multistressor Model, Michael Collins, Melody S. Clark, Manuela Truebano

School of Biological and Marine Sciences

The wild poses a multifaceted challenge to the maintenance of cellular function. Therefore, a multistressor approach is essential to predict the cellular mechanisms which promote homeostasis and underpin whole-organism tolerance. The intertidal zone is particularly dynamic, and thus, its inhabitants provide excellent models to assess mechanisms underpinning multistressor tolerance. Here, we critically review our current understanding of the regulation of the cellular stress response (CSR) under multiple abiotic stressors in intertidal organisms and consider to what extent a multistressor approach brings us closer to understanding responses in the wild. The function of the CSR has been well documented in laboratory …

Cannabis Use Disorder, Suicide Attempts, And Self-Harm Among Adolescents: A National Inpatient Study Across The United States, Adeolu Funso Oladunjoye, Elijah Li, Kammarauche Aneni, Edore Onigu-Otite

Faculty, Staff and Students Publications

Background: Suicide is among the top three causes of adolescent mortality. There is a scarcity of research examining cannabis use and suicidal behavior in adolescents.

Objectives: To determine the association between cannabis use disorder (CUD) and suicide attempt/self-harm in a hospitalized sample of adolescents.

Methods: We conducted a cross-sectional observation study using data from the Nationwide Inpatient Sample collected over four years from January 1, 2016, through December 31, 2019. We included adolescents aged 10-19 hospitalized during the above period (N = 807,105). The primary outcome was suicide attempt/self-harm and the main predictor was CUD. The International Classification of Diseases …

Blue Brief 2022-2023, University Of San Diego School Of Law

Blue Brief

A USD School of Law faculty review of selected rulings from the most recent Term of the United States Supreme Court.

Antimicrobial Resistance Profile Of Escherichia Coli Isolated From Poultry Litter, M. J. Khong, A. M. Snyder, M. M. Young, N. L. Barbieri, S. L. Weimer

Poultry Science Faculty Publications and Presentations

Antimicrobial resistance is a threat to animal and human health. As a commensal and zoonotic bacterium, Escherichia coli has the potential to be a pathogenic source of antimicrobial resistance. The purpose of this study aimed to investigate the antimicrobial resistance profile of E. coli isolated from litter collected from pens in a broiler chicken experiment. E. coli was isolated from litter samples (n = 68 isolates) of 16 pens housing broilers to d 53 of age. Resistance to 10 antimicrobials was observed by disc diffusion. The presence of 23 antimicrobial and heavy metal resistance genes, O serogroups, and avian pathogenic …

Situational Analysis And Urban Theory, Mark Davidson

Geography

Urban geographers have been pursuing divergent theoretical projects. Some have pushed urban theory to become ageographical, the goal being to search out and explain of a globally omnipotent urbanization process. Others have moved in a different direction, seeking to detail how singular constellations of processes produce only particular urban places. This theoretical divergence has led some to question whether middle-range urban theories continue to have purchase today. This paper seeks to contribute to this attempt to rekindle an interest in middle-range urban theory by examining the relevance of Karl Popper’s situational analysis to how we understand contemporary urbanization. © The …

Female And Male Leach's Storm Petrels (Hydrobates Leucorhous) Pursue Different Foraging Strategies During The Incubation Period, Robert A. Mauck, Isabeau Pratte, April Hedd, Ingrid L. Pollet, Patricia L. Jones, William A. Montevecchi, Robert A. Ronconi, Carina Gjerdrum, Sarah Adrianowyscz, Colin Mcmahon, Haley Acker, Liam U. Taylor, Jennifer Mcmahon, Donald Dearborn, Gregory J. Robertson, Laura A. Mcfarlane Tranquilla

All Faculty Scholarship

Reproduction in procellariiform birds is characterized by a single egg clutch, slow development, a long breeding season and obligate biparental care. Female Leach's Storm Petrels Hydrobates leucorhous, nearly monomorphic members of this order, produce eggs that are between 20 and 25% of adult bodyweight. We tested whether female foraging behaviour differs from male foraging behaviour during the ~ 44-day incubation period across seven breeding colonies in the Northwest Atlantic. Over six breeding seasons, we used a combination of Global Positioning System and Global Location Sensor devices to measure characteristics of individual foraging trips during the incubation period. Females travelled significantly …

Individual-Based Models Of Avian Migration For Estimating Behavioural Traits And Predicting Ecological Interactions, Benjamin A. Tonelli, Alan E. Zelin, Donald Dearborn, Morgan W. Tingley

All Faculty Scholarship

Rapid advances in the field of movement ecology have led to increasing insight into both the population-level abundance patterns and individual-level behaviour of migratory species. Despite this progress, research questions that require scaling individual-level understanding of the behaviour of migrating organisms to the population level remain difficult to investigate. To bridge this gap, we introduce a generalizable framework for training full-annual cycle individual-based models of migratory movements by combining information from tracking studies and species occurrence records. Focusing on migratory birds, we call this method: Models of Individual Movement of Avian Species (MIMAS). We implement MIMAS to design individual-based models …

Climate Services And Transformational Adaptation, Edward Carr

Sustainability and Social Justice

The Working Group II contribution to the IPCC’s Sixth Assessment Report states that effective adaptation to the changing climate will require transformational changes in how people live. This article explores the potential for climate services to catalyze and foster transformational adaptation. I argue that weather and climate information are not, in and of themselves, tools for transformation. When designed and delivered without careful identification of the intended users of the service and the needs that service addresses, they can fail to catalyze change amongst the users of that information. At worst, they can reinforce the status quo and drive maladaptive …

Network Intrusion Detection Using Deep Reinforcement Learning, Hamed T. Sanusi

College of Graduate Studies: Theses & Dissertations

This thesis delves into cybersecurity by applying Deep Reinforcement(DRL) Learning in network intrusion detection. One advantage of DRL is the ability to adapt to changing network conditions and evolving attack methods, making it a promising solution for addressing the challenges involved in intrusion detection. The thesis will also discuss the obstacles and benefits of using Classification methods for network intrusion detection and the need for high-quality training data. To train and test our proposed method, the NSL-KDD dataset was used and then adjusted by converting it from a multi-classification to a binary classification, achieved by joining all attacks into one. …

Function And Dysfunction Of The Dystonia Network: An Exploration Of Neural Circuits That Underlie The Acquired And Isolated Dystonias, Jason S Gill, Megan X Nguyen, Mariam Hull, Meike E Van Der Heijden, Ken Nguyen, Sruthi P Thomas, Roy V Sillitoe

Duncan NRI Faculty and Staff Publications

Dystonia is a highly prevalent movement disorder that can manifest at any time across the lifespan. An increasing number of investigations have tied this disorder to dysfunction of a broad "dystonia network" encompassing the cerebellum, thalamus, basal ganglia, and cortex. However, pinpointing how dysfunction of the various anatomic components of the network produces the wide variety of dystonia presentations across etiologies remains a difficult problem. In this review, a discussion of functional network findings in non-mendelian etiologies of dystonia is undertaken. Initially acquired etiologies of dystonia and how lesion location leads to alterations in network function are explored, first through …

Tnik Regulation Of Interferon Signaling And Endothelial Cell Response To Virus Infection, Khanh M Chau, Abishai Dominic, Eleanor L Davis, Sivareddy Kotla, Estefani Turcios Berrios, Arsany Fahim, Ashwin Arunesh, Shengyu Li, Dongyu Zhao, Kaifu Chen, Alan R Davis, Minh T H Nguyen, Yongxing Wang, Scott E Evans, Guangyu Wang, John P Cooke, Jun-Ichi Abe, David P Huston, Nhat-Tu Le

Faculty, Staff and Student Publications

BACKGROUND: Traf2 and Nck-interacting kinase (TNIK) is known for its regulatory role in various processes within cancer cells. However, its role within endothelial cells (ECs) has remained relatively unexplored.

METHODS: Leveraging RNA-seq data and Ingenuity Pathway Analysis (IPA), we probed the potential impact of TNIK depletion on ECs.

RESULTS: Examination of RNA-seq data uncovered more than 450 Differentially Expressed Genes (DEGs) in TNIK-depleted ECs, displaying a fold change exceeding 2 with a false discovery rate (FDR) below 0.05. IPA analysis unveiled that TNIK depletion leads to the inhibition of the interferon (IFN) pathway [-log (

SUMMARY: Our findings suggest that …

Wastewater Pandemic Preparedness: Toward An End-To-End Pathogen Monitoring Program, Justin R Clark, Austen Terwilliger, Vasanthi Avadhanula, Michael Tisza, Juwan Cormier, Sara Javornik-Cregeen, Matthew Clayton Ross, Kristi Louise Hoffman, Catherine Troisi, Blake Hanson, Joseph Petrosino, John Balliew, Pedro A Piedra, Janelle Rios, Jennifer Deegan, Cici Bauer, Fuqing Wu, Kristina D Mena, Eric Boerwinkle, Anthony W Maresso

Faculty, Staff and Student Publications

Molecular analysis of public wastewater has great potential as a harbinger for community health and health threats. Long-used to monitor the presence of enteric viruses, in particular polio, recent successes of wastewater as a reliable lead indicator for trends in SARS-CoV-2 levels and hospital admissions has generated optimism and emerging evidence that similar science can be applied to other pathogens of pandemic potential (PPPs), especially respiratory viruses and their variants of concern (VOC). However, there are substantial challenges associated with implementation of this ideal, namely that multiple and distinct fields of inquiry must be bridged and coordinated. These include engineering, …

Understanding The Relationship Between Landscape Characteristics And Public Preferences: A Case Study In A Proposed Appalachian Geopark Project In Southern West Virginia, United States, Ganga Nakarmi

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purpose of this dissertation was to understand the relationship between landscape characters and public preferences in the proposed Appalachian Geopark (pAGP) in southern West Virginia, United States (U.S.). This region was well-known for industrial activities such as coal mining logging and railways during the 1800s. With the diminishing industrial activities, the region was left behind with degraded environmental factors including landscapes and an economically challenged society. Because of these conditions, there is a need to develop this region without further damaging the lands and implement proper land management policies and practices. Understanding characteristics of those lands from the past …

What’S Long About Long John Silver: Anormative Masculinities And Histories In Robert Louis Stevenson’S Treasure Island, David V. Riser

Graduate Theses, Dissertations, and Problem Reports (ETD)

Historical queer and transgender experiences have been obscured by the dominant narrative of history. However, these experiences surface in works of fiction. This thesis analyzes affective responses to constructions of queer masculinity in Robert Louis Stevenson’s Treasure Island. Affects of disgust and desire in Treasure Island, and in the popular history of Treasure Island, reveal a proto-queer transgender experience found in 19th-century maritime fiction. These affects demonstrate a fear that there is no reproductive futurity in queer masculinity while producing narratives of queer masculinity. This production makes historical queer and transgender experiences legible, and allows contemporary queer readers to navigate …

“Bhat Khaiso?”: The Role Of Food In A Bangladeshi Community In The U.S., Jinia Meherin , '23

Senior Theses, Projects, and Awards

No abstract provided.

Formulaicity And Contexts: A Multimodal Analysis Of The Japanese Utterance-Final Tteyuu, Michiko Kaneyasu

World Languages and Cultures Faculty Publications

This study investigates the use of the utterance-final tteyuu [ʔtejɯː], a combination of the quotative particle tte and the verb yuu (‘say’). Although its lexicalized status and utterance-final occurrence are commonly observed, we still know little about its real-time functions. The analysis of 120 examples in varied contexts shows its general usage to clarify something expressed in the prior talk, which is a type of repair practice. More importantly, the analysis reveals how the participants’ understanding of the ongoing speech activity and multimodal cues affect its use and interpretation. Furthermore, some specialized usages appear to motivate activity-bound pragmatic inferencing, leading …

Multimodal Game-Based Learning In Post-Secondary Education, Nathan A. Vanos

EWU Masters Thesis Collection

In this age of unprecedented technological proliferation, educators have been given a unique opportunity to enhance classroom engagement. That opportunity is multimodal game-based learning (MGBL): classroom instruction through a combination of games and multiple modalities of information. Using today’s 3D systems and virtual reality tools, this concept can be explored to depths never before possible. The aim of this project was to design and implement an application that could be used to evaluate how MGBL could impact student engagement and learning, specifically at the post-secondary level. The application implemented during this work was a 3D and virtual reality Simulator for …

Reconstructing The Ecological Relationships Of The Latest Cretaceous Antarctic Dinosaurs And How Functional Tooth Morphology Influenced Diet And Ecological Niche Among Basal Ornithopod Dinosaurs, Ian Broxson

EWU Masters Thesis Collection

Of the final three connected Gondwanan landmasses, the dinosaur fossil record of Antarctica in the Cretaceous is the least complete. Most dinosaur faunas in this time period (145 Ma to 66.0 Ma) are widely separated geographically and temporally from one another by million years. However, a group of non-avian dinosaurs from the James Ross Basin (JRB) of the Antarctic Peninsula, composed of two elasmarians, a parankylosaurian ankylosaur, a hadrosaur and a suspected megaraptor, all are represented by fragmentary remains have emerged from the same horizon of the Sandwich Bluff Member (SBM) of the López de Bertodano Formation and were thus, …

Measuring The Production Of Migratory Westslope Cutthroat Trout In Tributaries To Priest River, Idaho, Collin J. Hendricks

EWU Masters Thesis Collection

Iteroparous salmonids that exhibit a migratory life history are essential to functioning metapopulations. They are demographically important as migratory females produce more eggs than non-migratory individuals. Additionally, they provide genetic support through gene flow, resulting in more robust, genetically diverse populations. The lower Priest River flows into the Pend Oreille River in the panhandle of northern Idaho and is a system susceptible to degrading conditions due to increasing water temperature. It is also, a significant contributor of migratory Westslope Cutthroat Trout Oncorhynchus clarkii lewisi (WCT) in the Clark- Fork Pend Oreille Basin (CFPOR). The goal of our study was to …

Extranormal Sorcery In Toni Morrison's Song Of Solomon, Harleyquinn Wahl

EWU Masters Thesis Collection

No abstract provided.

Investigation Of Small Mammal Species Richness, Abundance, And Genetic Population Structure On And Around The Eastern Washington University Prairie Restoration Site, Sarah Deshazer

EWU Masters Thesis Collection

Small mammals are an ecologically important component of every landscape on Earth. They are a food source for higher trophic level animals, disperse plant seed and mycorrhizal fungi spore, engineer the landscape through burrowing and foraging activities, and alter plant community composition through selective predation of seed and grain. Studies have shown that small mammals may help facilitate the transition between successive stages in prairie restoration. Eastern Washington University has dedicated 120 acres of campus land to restoration of native prairie habitat. Small mammals can play both a positive and a negative role in restoration, therefore it is important to …

Sexually-Divergent Differentiation And Inflammatory Response To Osteoclasts, Lilijanna L. Cummings

EWU Masters Thesis Collection

No abstract provided.

On Respect For Robots, Daniel Tigard

Philosophy: Faculty Scholarship

We spend a lot of time with robotic and artificially intelligent (AI) technologies today. At the same time, it appears that we are growing more accustomed to interacting with AI and robots as if they were fellow human beings. Such trends have aptly brought about increasing ethical discussions concerning how we should treat technological devices. Do we owe robots some degree of respect, and how could respecting robots be justified? With this article, I put forward a new way of answering these questions. I invoke a revisionist account of Kant’s ethics that amends the usual priority of dignity before respect …

Polymer Threadings And Rigidity Dictate The Viscoelasticity Of Entangled Ring-Linear Blends And Their Composites With Rigid Rod Microtubules, Karthik R. Peddireddy, Ryan Clairmont, Rae M. Robertson-Anderson

Physics and Biophysics: Faculty Scholarship

Mixtures of polymers of varying topologies and stiffnesses display complex emergent rheological properties that often cannot be predicted from their single-component counterparts. For example, entangled blends of ring and linear polymers have been shown to exhibit enhanced shear thinning and viscosity, as well as prolonged relaxation timescales, compared to pure solutions of rings or linear chains. These emergent properties arise in part from the synergistic threading of rings by linear polymers. Topology has also been shown to play an important role in composites of flexible (e.g., DNA) and stiff (e.g., microtubules) polymers, whereby rings promote mixing while linear polymers induce …

Connecting Antibiotic Resistance To The Environment (Care): Introducing A Novel Framework Integrating Chemical Cross-Resistance And Place-Based Engagement To The Blue Marsh Watershed In Reading, Pennsylvania, Jill Felker

Antioch University Dissertations & Theses

Antibiotic resistance is a serious health threat around the world. Millions of individuals are infected with antibiotic-resistant bacteria yearly, and thousands die from previously curable illnesses. Although antibiotic resistance occurs naturally, misuse of antibiotics accelerates the loss of their effectiveness. Public health campaigns focusing on antibiotic awareness have not effectively communicated and educated the public on this health crisis. New efforts to combat antibiotic resistance are urgently needed. This dissertation focuses on the ecological and public health components of antibiotic resistance research that must be addressed to decelerate antibiotic resistance. A new interdisciplinary theoretical framework was developed to Connect Antibiotic …

Eating Change: A Critical Autoethnography Of Community Gardening And Social Identity, Jessica Gerrior

Antioch University Dissertations & Theses

Community gardening efforts often carry a social purpose, such as building climate resilience, alleviating hunger, or promoting food justice. Meanwhile, the identities and motivations of community gardeners reflect both personal stories and broader social narratives. The involvement of universities in community gardening projects introduces an additional dimension of power and privilege that is underexplored in scholarly literature. This research uses critical autoethnography to explore the relationship of community gardening and social identity. Guided by Chang (2008) and Anderson and Glass-Coffin (2013), a systematic, reflexive process of meaning-making was used to compose three autoethnographic accounts. Each autoethnography draws on the author’s …

How Cultural Believes Support And Perpetuate Relational Violence: A Delphi Study For Violence Prevention, Alisha D. Guthery

Antioch University Dissertations & Theses

This study solicited experts in relational violence across the United States using the Delphi methodology and grounded theory. This research was conducted in two phases and designed to answer two primary questions: (1) What cultural beliefs are involved in relational violence in the United States? And (2) How are the beliefs about relational violence maintained? The findings showed agreement from the experts on the societal beliefs that hold relational violence, the specific beliefs held by the abuser, and the impacts of these beliefs on the survivor. The experts offered ideas for intervention and prevention, which are important contributions to professional …

A Constructivist Grounded Theory Analysis Of Seven Medical Provider Perspectives On Major Barriers To Prescribing Buprenorphine To Youth With Opiold Use Disorder In Outpatient Medical Settings: "We Should Be Providing Them With What We Know To Be The Gold Standard Of Care"., Maeve O'Leary Sloan

Antioch University Dissertations & Theses

This study utilized Primary Care Provider (PCP) perspectives to unveil major barriers to prescribing buprenorphine to youth (ages 16-25) with opioid use disorder (OUD). Semi-structured interviews were conducted with seven PCPs recruited through convenience and snowball sampling. Interviews were conducted and recorded via Zoom video conferencing. Transcripts were generated and analyzed for themes using a Constructivist Grounded Theory (CGT) approach. The CGT of the present study describes four major barriers that limit PCP prescription of buprenorphine to youth: 1) PCPs Feel Overwhelmed, 2) PCPs Feel Ill Equipped to Treat Youth Patients with OUD, 3) PCPs Hold and Observe Stigma toward …

Exploring The Lives Of Animal Activists: A Qualitative Study, Erin K. Mckenney

Antioch University Dissertations & Theses

The animal rights movement, despite its historical roots, has only recently garnered attention in the realm of social sciences, increasingly being recognized as a facet of social justice. This dissertation delves into the intersection of animal rights activism and gender, primarily focusing on the parallels drawn between the oppression of women and animals/nature. The noticeable dominance of women in the animal rights movement, as suggested by previous studies, formed the basis for adopting an eco-feminist approach to explore this issue, highlighting the shared oppression and exploitation faced by women and animals. In-depth, in-person interviews were used to collect data on …

Bringing Light To The Unconscious: A Theoretical Examination Of Racism Through The Adlerian Lens Of Social Interest, Elle R. Harris

Antioch University Dissertations & Theses

This theoretical paper posits that racial oppression ensues in part due to a lack of social interest, manifested by excessive self-interest in the projection of negative white attributions onto people of color. Excessive white self-interest not only divides whites and Black people but within people groups and among individuals; all are negatively impacted by racism, and to believe otherwise is to succumb to the dangerous falsity of zero-sum thinking. Furthermore, a scholarly case is made for the amplification of social interest by a lowering of white defenses and a reclamation of one’s authentic parts of self. Specifically, one must acknowledge, …