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2023

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Book Review: Ain't Burned All The Bright, Rachel Billings Jan 2023

Book Review: Ain't Burned All The Bright, Rachel Billings

The Utah English Journal

Ain't Burned All the Bright captures the anxieties, fears, and tensions of 2020 clearly and vividly even though it consists of only three long sentences. Jason Reynolds tells the story of a Black boy and his family during the Covid-19 quarantine and pandemic. Through the prose of Reynolds and illustrations of Jason Griffin, the reader learns what the pandemic was like from the point of view of a typical teenager.


Fall 2023 Editor’S Note, Mikayla Johnson Jan 2023

Fall 2023 Editor’S Note, Mikayla Johnson

Inscape

We all believe in something, we have to believe in something, otherwise what keeps us going, really, at the end of the day, in the twists and turns and ups and downs and heartbreaks and heart stops of day-to-day living; this is what I tell myself, what you tell yourself, what he or she and they and we all tell ourselves, whenever the clock stops, or the eyes close, or the screen turns black.


The Politicization Of Criminal Prosecutions, Wadie E. Said Jan 2023

The Politicization Of Criminal Prosecutions, Wadie E. Said

Publications

This Article offers a critical review of how political considerations rooted both in domestic and foreign policy-have distorted the criminal process, thereby offering a complementary analysis of what ails the criminal justice system. This analysis builds on the by-now well-known critiques of the racial and socioeconomic discrimination at the system's heart. The result is a criminal justice system that allows political considerations to dictate results far more than they should. In domestic prosecutions, criminal law is mostly used to target those who seek to question the legitimacy of state policies, state agencies (especially the police), or corporate interests, rendering the …


Privacy Peg, Trade Hole: Why We (Still) Shouldn’T Put Data Privacy In Trade Law, Margot E. Kaminski, Kristina Irion, Svetlana Yakovleva Jan 2023

Privacy Peg, Trade Hole: Why We (Still) Shouldn’T Put Data Privacy In Trade Law, Margot E. Kaminski, Kristina Irion, Svetlana Yakovleva

Publications

No abstract provided.


The Shifting Economic Allegiance Of Capital Gains, Amanda Parsons Jan 2023

The Shifting Economic Allegiance Of Capital Gains, Amanda Parsons

Publications

Technological advances and the digitalization of the global economy have created an economic environment beyond the imagination of the original designers of the international tax system. Much scholarly attention has been paid to the question of how these economic transformations should affect which country is able to tax a multinational company's income. But which country should be able to tax capital gains income from the sale of that company's shares is an important and overlooked question.

This Article answers this question. It concludes that taxing authority over capital gains income must be reallocated to the countries in which companies conduct …


Catch And Release Jurisdiction, Adam B. Sopko Jan 2023

Catch And Release Jurisdiction, Adam B. Sopko

Publications

No abstract provided.


Understanding The Implications Of Work Based Learning For Students Pk-12 School Systems Institutions Of Higher Education And Hosting Organizations, David Naff, Amy Corning, Meleah Ellison, Albion Sumrell, Zehra Sahin Ilkorkor, Jennifer Murphy, Ciana Cross Jan 2023

Understanding The Implications Of Work Based Learning For Students Pk-12 School Systems Institutions Of Higher Education And Hosting Organizations, David Naff, Amy Corning, Meleah Ellison, Albion Sumrell, Zehra Sahin Ilkorkor, Jennifer Murphy, Ciana Cross

MERC Publications

This literature review by the Metropolitan Educational Research Consortium (MERC) and Institute for Collaborative Research and Evaluation (ICRE), in partnership with the Virginia Talent + Opportunity Partnership (V-TOP) and State Council of Higher Education for Virginia (SCHEV) explores work-based learning and its implications for PK-12 institutions, institutions of higher education, and hosting organizations (e.g. employers). The report also provides background information about the foundations of work-based learning and concludes with a series of recommendations for practice, policy, and future research related to work-based learning. There is also an accompanying podcast episode where report authors discuss the key takeaways with …


Full Issue Jan 2023

Full Issue

Inscape

No abstract provided.


The Nephite Metaphor Of Life As A Probation: Rethinking Nephi’S Portrayal Of Laman And Lemuel, Noel B. Reynolds Jan 2023

The Nephite Metaphor Of Life As A Probation: Rethinking Nephi’S Portrayal Of Laman And Lemuel, Noel B. Reynolds

Interpreter: A Journal of Latter-day Saint Faith and Scholarship

Commentaries on Nephi’s first book tend to interpret the fraternal struggles it reports as historical facts that are meant primarily to invite readers’ evaluative responses. While recognizing the historical character of the facts marshalled by Nephi, this paper will argue that the author transposes that history into an allegory meant to inspire his readers in all times and places to abandon prevailing metaphors of life that are focused on the attainment of worldly goods and pleasures. In their place, Nephi offers the revealed metaphor of life as a day of probation taught to him and his father in their great …


People Are Curious About Immoral And Morally Ambiguous Others, Jordan Wylie, Ana Gantman Jan 2023

People Are Curious About Immoral And Morally Ambiguous Others, Jordan Wylie, Ana Gantman

Publications and Research

Looking to the popularity of superheroes, true crime stories, and anti-heroic characters like Tony Soprano, we investigated whether moral extremity, especially moral badness, piques curiosity. Across five experiments (N = 2429), we examine moral curiosity, testing under what conditions the moral minds of others spark explanation-seeking behavior. In Experiment 1, we find that among the most widely watched Netflix shows in the US over a five-month period, the more immoral the protagonist, the more hours people spent watching. In Experiments 2a and 2b, we find that when given a choice to learn more about morally good, bad, ambiguous, or …


Djurberg & Berg: A Relationship Saga, Johanna Graflund Jan 2023

Djurberg & Berg: A Relationship Saga, Johanna Graflund

MA Theses

Djurberg & Berg is one of the most famous artistic duos in today’s contemporary global art market. This thesis will pinpoint crucial relationships and important career milestones that helped them achieve international recognition and success. As this thesis argues, one of the most important relationships is with Moderna Museet. Moderna Museet is a well-renowned top-tier museum that brings legitimacy to the artists it shows. As a government-funded museum, it is responsible for promoting Swedish art, and artists can not go unnoticed.
Along with Moderna Museet, the duo has established vital support from major
institutions such as the Fondazione Prada and …


Art Investment Funds And Nfts, Francesca Osborne Jan 2023

Art Investment Funds And Nfts, Francesca Osborne

MA Theses

Art price inflation, rising levels of wealth, and the artworld’s financialization have
/="/">changed the way investors view the art market. In an attempt to capture the
/="/">momentous returns realized by successful collectors, art investment funds have
/="/">emerged with the conviction art can be used as a speculative or strategic alternative asset. However, the majority of art funds have been dissolved or put on hold. This paper examines the investment characteristics of fine art to uncover the rationale for art investment fund failures, finding the art market’s inefficiency as the foremost explanation. Subsequently, non-fungible token (NFT) art and …


De Beer/De Boer Family Collection, Elena Lee, Sara R. Huyser Jan 2023

De Beer/De Boer Family Collection, Elena Lee, Sara R. Huyser

Finding Aids

The De Beer/De Boer Family Collection spans 130 years of family history in Sioux County, Iowa. The De Beer/De Boer families are descendants of the pioneer E. J. G. Bloemendaal. The collection highlights Christian educational materials, both in schools and churches. It also includes a scrapbook about a serviceman’s military career during World War II, as well as the progression of land ownership by farmers in Sioux County. Family photographs depict day-to-day 19th-century farm life, especially children playing outdoors. There are also 18 personal letters written by Gerhard and Ann Scholten (in Dutch) from Chicago in 1883.


“It Must Needs Be”, Eric Dahlin Jan 2023

“It Must Needs Be”, Eric Dahlin

BYU Studies

After speaking to his son Jacob about Jesus Christ’s redemption of mankind, the Book of Mormon prophet Lehi declares, “It must needs be, that there is an opposition in all things” (2 Ne. 2:11). We often use the word opposition colloquially to explain the difficulties or challenges that we or others encounter. When others experience troubling times, we frequently, as well-intentioned members of the Church, remind them of this sentiment. Our aim is to provide solace for the one who is suffering by pointing out that facing opposition is a common feature of life (even if normalizing the suffering may …


Your Daddy Or Your Father?— Mimetic Desire Versus Christian Fatherhood, Bryce Dixon Jan 2023

Your Daddy Or Your Father?— Mimetic Desire Versus Christian Fatherhood, Bryce Dixon

BYU Studies

“The Yankees are my Daddy,” the Boston Red Sox pitcher Pedro Martinez famously announced following the loss of some critical baseball games to their New York City rivals. The idiom “Daddy” refers to a victor’s domination over a loser in a competition. The winner becomes the Daddy, and the loser the submissive child. Ironically, a Red Sox player, David Ortiz—nicknamed “Big Papi,” or “Big Daddy” in Spanish—became the Yankees’ “Daddy” when his batting heroics led the Red Sox to a miraculous comeback win over the Yankees in the 2004 playoffs, reversing the “curse of the Bambino” that was believed to …


The Role Of Mkp-2 In Cellular Senescence And Metabolic Function, Morgan Welch Jan 2023

The Role Of Mkp-2 In Cellular Senescence And Metabolic Function, Morgan Welch

Theses

Senescence is a state of permanent cell cycle arrest which stops proliferation. It is hallmarked by changes in proteins such as p21, p53, and p16, which are regulated by mitogen-activated protein kinases (MAPKs) which are regulated by MAPK Phosphatases (MKPs). One such MKP, MKP-2, has a paucity of information on its physiological function. To study MKP-2 in senescence, we used mouse embryonic fibroblasts (MEFs) derived from novel MKP-2 whole-body knockout mice. These MEFs were analyzed using senescence-associated β-galactosidase assays and immunoblotting approaches. It was found that there were reduced β-Galactosidase positive cells and reduced senescence phenotypes in the Mkp2 -/- …


Evaluation Of Amnion Chorion Membrane For Socket Preservation After The Extraction Of Maxillary Single Rooted Teeth: A Randomized Controlled Clinical Trial, Karim Soussi, Nayer Aboelsaad, Ziad Aly Jan 2023

Evaluation Of Amnion Chorion Membrane For Socket Preservation After The Extraction Of Maxillary Single Rooted Teeth: A Randomized Controlled Clinical Trial, Karim Soussi, Nayer Aboelsaad, Ziad Aly

International Arab Journal of Dentistry

Introduction: The aim of this study was to assess the efficiency of using dehydrated de-epithelialized amnion chorion membrane (ddACM) on socket preservation in the anterior region, clinically and radiographically.

Methods: 26 unrestorable maxillary anterior or single rooted premolars, with buccal fenestration, were selected. The socket was filled with allograft material and covered with ddACM for the test group, and allograft material with a collagen membrane for the control group divided equally. Clinical parameters including gingival healing and tissue thickness was assessed. Volumetric bone change was measured 4 months later using a CBCT.

Results: Test group showed clinical …


Seasonal Vulnerability Of Snakes To Road Traffic At Wheeler National Wildlife Refuge, Jackson S. Schoettle Jan 2023

Seasonal Vulnerability Of Snakes To Road Traffic At Wheeler National Wildlife Refuge, Jackson S. Schoettle

Theses

Snakes are important predators and prey in North American food webs that exhibit seasonal activity patterns in temperate regions. During periods of heightened activity, they will often utilize roads both for traveling from one habitat patch to another and/or for thermoregulation. In this thesis, I explore how human recreational activities impact the diversity and distribution of snake communities by examining the relationships between seasonality of human recreational activities and gravel road closures for waterfowl management on snake road mortality and activity at Wheeler National Wildlife Refuge in northern Alabama, USA. Many studies have investigated how snakes interact with paved roads, …


United States Department Of Labor Scientific Integrity Policy Jan 2023

United States Department Of Labor Scientific Integrity Policy

Copyright, Fair Use, Scholarly Communication, etc.

United States Department of Labor Scientific Integrity Policy


Molecular Mechanism Behind The Safe Immunostimulatory Effect Of Withania Somnifera, Kriti Kalpana, Shen Yap, Moriya Tsuji, Akira Kawamura Jan 2023

Molecular Mechanism Behind The Safe Immunostimulatory Effect Of Withania Somnifera, Kriti Kalpana, Shen Yap, Moriya Tsuji, Akira Kawamura

Publications and Research

Withania somnifera (L.) Dunal (family Solanaceae) is a medicinal plant known for, among many pharmacological properties, an immune boosting effect. Our recent study revealed that its key immunostimulatory factor is lipopolysaccharide of plant-associated bacteria. This is peculiar, because, although LPS can elicit protective immunity, it is an extremely potent pro-inflammatory toxin (endotoxin). However, W. somnifera is not associated with such toxicity. In fact, despite the presence of LPS, it does not trigger massive inflammatory responses in macrophages. To gain insights into the safe immunostimulatory effect of W. somnifera, we conducted a mechanistic study on its major phytochemical constituent, …


The Trichobezoar Enigma: Untangling The Intricacies Of Rapunzel Syndrome, Debabrata Sahu, Dr Rajkishor Sahu Jan 2023

The Trichobezoar Enigma: Untangling The Intricacies Of Rapunzel Syndrome, Debabrata Sahu, Dr Rajkishor Sahu

Digital Journal of Clinical Medicine

Rapunzel Syndrome is a rare manifestation of trichobezoar, characterized by the presence of hair strands extending beyond the stomach and into the duodenum. Trichobezoars typically develop in individuals with a history of trichotillomania, a compulsive behavioral disorder involving hair-pulling, combined with trichophagia, the ingestion of hair. While trichobezoars predominantly form within the stomach, their occurrence in the jejunum is infrequent. This condition is more commonly observed in adolescent females.

The formation of bezoars within the gastrointestinal tract is typically attributed to anatomical changes. However, in cases where no such anatomical abnormalities are present, psychiatric disorders like trichotillomania can lead to …


8th International Galliformes Symposium (East Java, Indonesia: October 9-13, 2023): Book Of Abstracts, Iucn-Ssc Galliformes Specialist Group, World Pheasant Association, Geoffrey Davison Jan 2023

8th International Galliformes Symposium (East Java, Indonesia: October 9-13, 2023): Book Of Abstracts, Iucn-Ssc Galliformes Specialist Group, World Pheasant Association, Geoffrey Davison

Galliformes Specialist Group and Affiliated Societies: Conference Proceedings

Overview of the research and conservation of Galliformes in Indonesia, Jon-Paul Rodriguez

Overview of the research and conservation of Galliformes in Indonesia, Dewi M. Prawiradilaga

Impact of climate change and human pressure on Galliformes, Nurul L. Winarni and Habiburrachman A. H. Fuad

Distribution model of the great argus pheasant in the Bukit Barisan Selatan National Park, Femei Rahmilija, Jarwadi Budi Hernowo, and Lilik Budi Prasetyo

Surviving logging: The persistence of pheasants in sustainably managed logged forests in east Kalimantan, Indonesia, Agus Sudibyo Jati, Hiromitsu Samejima, and Kanehiro Kitayama

Respect for nature, respect for people: successful community-based conservation could lead to …


Molecular Target And Circuitry Underlying The Preclinical Effects Of Psychedelics In Models Of Opioid Use Disorder, Alaina M. Jaster Jan 2023

Molecular Target And Circuitry Underlying The Preclinical Effects Of Psychedelics In Models Of Opioid Use Disorder, Alaina M. Jaster

Theses and Dissertations

Opioid use disorder (OUD), like other substance use disorders (SUD), is characterized by maladaptive behavioral allocation away from other rewarding aspects of life following prolonged use, as well as large rates of relapse. While pharmacotherapies exist for OUD, they tend to only target the opioid receptors rather than the underlying mechanisms behind the maladaptive behaviors. Serotonin (5-hydroxytryptamine; 5-HT) is involved in modulation of cravings and regulation of motivational reward-related behaviors, thought to be due to a top-down processing method of external and internal stimuli. Serotonin 2A receptors (5-HT2AR) are widespread throughout the brain and most densely populate layer …


Contribution Of Metabolic Cell Swelling On Microcirculatory Perfusion In Septic Shock, Charles E. Payne Jan 2023

Contribution Of Metabolic Cell Swelling On Microcirculatory Perfusion In Septic Shock, Charles E. Payne

Theses and Dissertations

Sepsis, a systemic immunological response that leads to organ-dysfunction, the development of septic shock, and death has mortality rate of 15-25%. A subset of sepsis, septic shock, has an in-hospital mortality rate of 30-50%. Sepsis and its treatment are the most expensive healthcare problem in the United States with the US Agency for Healthcare Research and Quality estimating annual costs over $20 billion. Hypoxia experienced in septic shock induces metabolic cell and tissue swelling leading to further microcirculatory dysfunction and poor tissue perfusion. Reversing metabolic cell swelling corrects these perfusion defects. Two models were used in rats to induce septic …


Dune Building Dynamics Impact Cross-Island Connectivity And Barrier Island Characteristics, Alexander Sabo Jan 2023

Dune Building Dynamics Impact Cross-Island Connectivity And Barrier Island Characteristics, Alexander Sabo

Theses and Dissertations

Located at the land-sea interface, barrier islands are important protective features that reduce wave energy and erosion from mainland areas. Further, barrier islands provide habitat for many different organisms and serve as popular areas for recreation and tourism. As sandy landforms, barrier islands are easily disturbed, but often recover after disturbance as a result of island plant communities, specifically dune building grasses. Disturbance on barrier islands is driven by storms, tides, and overwash events. After disturbance has occurred, dune grasses colonize the dunes allowing for dune building and habitat restoration. On the Virginia barrier islands, there are three dominant dune …


Pre-Clinical Trials With Precision-Medicine Based Therapeutics In Basal-Like Patient-Derived Xenografts, David C. Boyd Jan 2023

Pre-Clinical Trials With Precision-Medicine Based Therapeutics In Basal-Like Patient-Derived Xenografts, David C. Boyd

Theses and Dissertations

Breast cancer treatments have improved over time, but the diseases seeing the most benefit from these improvements have the estrogen receptor, progesterone receptor, or are positive for HER2. Basal-like breast cancer tends to not have these biomarkers, which necessitates their treatment to be traditional, untargeted therapeutics which are less effective and tend to have harsh adverse effect profiles – this is an important unmet need. These studies utilize a variety of techniques, including tissue culture, viability assays, high-throughput screening, in vivo drug treatments and imaging, pathway analyses, molecular techniques such as Western blot, antibody arrays, RNA sequencing, sc RNA sequencing, …


Intrinsic Efficacy As A Determinant Of Opioid Effectiveness In Treatment Of Pain-Depressed Behavior, Edna Santos Jan 2023

Intrinsic Efficacy As A Determinant Of Opioid Effectiveness In Treatment Of Pain-Depressed Behavior, Edna Santos

Theses and Dissertations

Pain is a major public health concern that is commonly associated with behavioral depression, and a major goal in pain treatment is alleviation of pain-related behavioral depression. High-efficacy mu opioid receptor (MOR) agonists (e.g. fentanyl, morphine, oxycodone) are effective to treat pain, but their use is limited by side effects that not only endanger the patient but may also obscure analgesic rescue of pain-depressed behavior. The ongoing epidemic of opioid abuse and overdose deaths has stimulated research to discover non-opioid alternative analgesics; however, this search neglects the clinical potential of safer intermediate-efficacy MOR agonists (e.g. buprenorphine). The objective of the …


X-Ray Crystallography: A Tool For Understanding Protein Function And Drug Discovery, Akua K. Donkor Jan 2023

X-Ray Crystallography: A Tool For Understanding Protein Function And Drug Discovery, Akua K. Donkor

Theses and Dissertations

Structural biology has become an indispensable tool for determining the 3D structures of proteins for a comprehensive understanding of their functions on molecular level, and for elucidating binding cavities that can be targeted for structure-based drug discovery. X-ray crystallography, the most widely used structural biology technique was utilized in addition to other techniques to: (1) understand the role of pyridoxal reductase (PDXI) in pyridoxal 5’-phosphate (PLP) homeostasis; (2) Determine whether the putative PLP binding protein, YggS, is involved in PLP homeostasis; (3) Elucidate the molecular basis underlying Agrobacterium receptor VirA pathogenesis; and (4) Elucidate the structural basis of aromatic aldehydes …


Unraveling The Consequence Of Adult Onset Sulfatide Depletion: Its Implications In Myelin And Axonal Heath In The Context Of Neurodegenerative Disease, Elizabeth Dustin Jan 2023

Unraveling The Consequence Of Adult Onset Sulfatide Depletion: Its Implications In Myelin And Axonal Heath In The Context Of Neurodegenerative Disease, Elizabeth Dustin

Theses and Dissertations

Multiple Sclerosis is an immune mediated disease of the CNS. MS is diagnosed through detection of demyelinated regions. However, recent studies demonstrate that Normal Appearing White Matter (NAWM) contains substantial pathology. One such pathology observed in the NAWM is the reduction of sulfatide. The proper stoichiometry of lipids in myelin acts to maintain rapid conduction velocity, provide trophic support to the neuron, and protect the axon from degeneration. We previously characterized a mouse lacking sulfatide’s synthesizing enzyme, CST through constitutive gene disruption and demonstrate that sulfide is required for proper stability of the myelin sheath. However, since MS is typically …


Development Of Tangible Code Blocks For The Blind And Visually Impaired, Hyun Woo Kim Jan 2023

Development Of Tangible Code Blocks For The Blind And Visually Impaired, Hyun Woo Kim

Theses and Dissertations

The fields of Science, Technology, Engineering, and Mathematics (STEM) have been growing at an accelerating rate in recent times. Knowing how to program has become one key skill for entering all of these STEM fields. However, many students find programming difficult. The block based programming language, Scratch, was specifically designed to lower hurdles to learning how to program for sighted students. Unfortunately, although very effective and widely used in K12 classrooms, Scratch, similar to other block based languages, is inaccessible to students who are blind and visually impaired (BVI). This thesis is part of a larger project to make the …