Digital Commons Network^™

Investigation Of The Segment Polarity Network In The Tardigrade Hypsibius Exemplaris, Taylor R. Harrison

UNF Graduate Theses and Dissertations

Segmentation has facilitated the evolution of the many forms of the panarthropods. Downstream regulation of segmentation is controlled by the highly conserved segment polarity network which includes the genes engrailed (en), hedgehog (hh), wingless (wg), cubitus interruptus (ci), patched (ptc), and smoothend (smo). While a high level of conservation has been seen in both the arthropods and onychophorans, only en has been described in any representatives of Tardigrada. Previous work had already established the loss of wg, which encodes for a Wnt ligand, in the tardigrade H. exemplaris …

Rethinking ‘Responsibility’ In Precision Agriculture Innovation: Lessons From An Interdisciplinary Research Team, Edward Prutzer, Maaz Gardezi, Donna M. Rizzo, Mary Emery, Scott Merrill, Benjamin E.K. Ryan, Panagiotis D. Oikonomou, Juan P. Alvez, Damilola T. Adereti, Rubaina Anjum, Appala R. Badireddy, Dwarika Bhattarai, Skye Brugler, Nicholas Cheney, David Clay, Sharon Clay, Ali Dadkhah, Joshua W. Faulkner, Deepak R. Joshi, Christopher Koliba, John Mcmaine, Semhar Michael, Sardorbek Musayev, Jarlath O’Neil-Dunne, George Pinder, Taylor Ricketts, Andrew W. Schroth, Scott Turnbull, Asim Zia

Department of Agricultural Leadership, Education, and Communication: Faculty Publications

We examine the interactions, decisions, and evaluations of an interdisciplinary team of researchers tasked with developing an artificial intelligence-based agricultural decision support system that can provide farmers site-specific information about managing nutrients on their land. We answer the following research questions: (1) How does a relational perspective help an interdisciplinary team conceptualize ‘responsibility’ in a project that develops precision agriculture (PA)? and (2) What are some lessons for a research team embarking on a similar interdisciplinary technology development project? We show that how RI is materialized in practice within an interdisciplinary research team can produce different understandings of responsibility, notions …

An Establishment Clause Eulogy: The Rise And Fall Of The Status/Use Distinction, Leo O'Malley

Notre Dame Journal of Law, Ethics & Public Policy

No abstract provided.

Defending The Fundamental Rights Of Parents: A Response To Recent Attacks, Melissa Moschella

Notre Dame Journal of Law, Ethics & Public Policy

No abstract provided.

A Right Defined By A Duty: The Original Understanding Of Parental Rights, Luray Buckner

Notre Dame Journal of Law, Ethics & Public Policy

No abstract provided.

Smith To Smithereens? If So, What’S Next?, Joshua Lacoste

Notre Dame Journal of Law, Ethics & Public Policy

No abstract provided.

Rationing Access, Roy Baharad, Gideon Parchomovsky

Vanderbilt Law Review

Protection of common natural resources is one of the foremost challenges facing our society. Since Garrett Hardin published his immensely influential The Tragedy of the Commons, theorists have contemplated the best way to save common-pool resources-—national parks, fisheries, heritage sites, and fragile ecosystems-—from overuse and extinction. These efforts have given rise to three principal methods: private ownership, community governance, and use restrictions. In this Essay, we present a different solution to the commons problem that has eluded the attention of theorists: access rationing. Access rationing measures rely not only on restrictions on the number of users but also on a …

The Molecular Circadian Clock Of Phox2b-Expressing Cells Drives Daily Variation Of The Hypoxic But Not Hypercapnic Ventilatory Response In Mice, Aaron A. Jones, Gabriella M. Marino, Allison R. Spears, Deanna M. Arble

Biological Sciences Faculty Research and Publications

While the suprachiasmatic nucleus (SCN) controls 24-h rhythms in breathing, including minute ventilation (V_E), the mechanisms by which the SCN drives these daily changes are not well understood. Moreover, the extent to which the circadian clock regulates hypercapnic and hypoxic ventilatory chemoreflexes is unknown. We hypothesized that the SCN regulates daily breathing and chemoreflex rhythms by synchronizing the molecular circadian clock of cells. We used whole-body plethysmography to assess ventilatory function in transgenic BMAL1 knockout (KO) mice to determine the role of the molecular clock in regulating daily rhythms in ventilation and chemoreflex. Unlike their wild-type littermates, BMAL1 …

In Light Of Breathing: Environmental Light Is An Important Modulator Of Breathing With Clinical Implications, Aaron A. Jones, Deanna M. Arble

Biological Sciences Faculty Research and Publications

In vertebrate animals, the automatic, rhythmic pattern of breathing is a highly regulated process that can be modulated by various behavioral and physiological factors such as metabolism, sleep–wake state, activity level, and endocrine signaling. Environmental light influences many of these modulating factors both indirectly by organizing daily and seasonal rhythms of behavior and directly through acute changes in neural signaling. While several observations from rodent and human studies suggest that environmental light affects breathing, few have systematically evaluated the underlying mechanisms and clinical relevance of environmental light on the regulation of respiratory behavior. Here, we provide new evidence and discuss …

Thermal Temperatures And Social Network Position In Bonobos, Dain Rust

UNF Graduate Theses and Dissertations

In a variety of species, the maintenance of stable social connections is associated with lower levels of stress in individuals. Understanding how physiological stress responses interact reciprocally with social connections in bonobos, humans closest living relative, can provide useful information about both the emergence of social connections in our own species, as well as provide guidance for animal welfare procedures. Infrared thermography (IRT) has been shown to be a reliable non-invasive measure of stress response in some species, specifically non-human primates. The current study examines the relationship between baseline facial temperatures, social network position, and demographic variables in a population …

Analyzing Physiological Signals During The Menstrual Cycle: Introducing An Application Of Circular Statistics, Krystal D. Sides

UNF Graduate Theses and Dissertations

Physiological signals are used in engineering and the sciences to determine the state of functionality of certain physiological systems such as the human endometrium. Many women use the basal body temperature method to track ovulation, or their fertile window. However, temperature tracking alone is subject to environmental factors. Non-invasive wearable devices can be tools in recording cycle-related physiological features relevant to women’s health research. This research uses the Empatica E4 wristband to track changes in the physiological features during sleep across the menstrual cycle of ovulating and non-ovulating females. Due to the cyclic nature of menstrual cycles, analytic solutions to …

A Predator-Prey Biological Model With Combined Birth Rates, Self-Limitation And Competition Terms, Joon Hyuk Kang, Lucinda Ford

Faculty Publications

The purpose of this paper is to give sufficient conditions for the existence and uniqueness of positive solutions to a rather general type of elliptic system of the Dirichlet problem on a bounded domain Ω in Rn. Also considered are the effects of perturbations on the coexistence state and uniqueness. The techniques used in this paper are super-sub solutions method, eigenvalues of operators, maximum principles, spectrum estimates, inverse function theory, and general elliptic theory. The arguments also rely on some detailed properties for the solution of logistic equations. These results yield an algebraically computable criterion for the positive coexistence of …

Culinary Globalization In Delhi: Filipino Sushi Chefs As Cultural Intermediaries, Jozon A. Lorenzana

Department of Communication Faculty Publications

Culinary globalization in Indian cities has resulted in new patterns of food consumption and production. Aside from the increasing presence of global franchises such as Costa Coffee, McDonald’s and Kentucky Fried Chicken, local and foreign entrepreneurs have established restaurants that offer various national cuisines. In Delhi, for example, Japanese-themed restaurants cater to the city’s growing appetite for new culinary experiences. So far our knowledge of culinary globalization in Indian cities has focused on consumption: How emerging gastronomic patterns relate to identity formations. The production of cuisines as part of the city’s culinary globalization is rarely explored. In this paper; I …

Abmr: An R Package For Agent-Based Model Analysis Of Large-Scale Movements Across Taxa, Benjamin Gochanour, Javier Fernández-López, Andrea Contina

School of Integrative Biological & Chemical Sciences Faculty Publications

1. Agent-based modelling (ABM) shows promise for animal movement studies. However, a robust, open-source and spatially explicit ABM coding platform is currently lacking.
2. We present abmR, an R package for conducting continental-scale ABM simulations across animal taxa. The package features two movement functions, each of which relies on the Ornstein–Uhlenbeck (OU) process.
3. The theoretical background for abmR is discussed and the main functionalities are illustrated using example populations.
4. Potential future additions to this open-source package may include the ability to specify multiple environmental variables or to model interactions between agents. Additionally, updates may offer opportunities for disease ecology and integration with …

The Relationship Between Campus Dining, Student Learning, And Student Success, John Boswell

Graduate Research Theses & Dissertations

Campus dining does more than provide sustenance to a campus community. Campus dining is an integral part of student success and learning. Limited research has looked at the impact of campus dining, particularly in the areas of student success and learning. The purpose of this qualitative case study was to explore how campus dining directors in the Mid-American Conference (MAC) perceived how themselves and their dining programs impact student learning and success. Data was collected through interviews with MAC campus dining directors and through observations made on their campus dining websites. Three themes emerged from the research on ways campus …

Influence Of Land Use, Precipitation, And Seasonality On Surface Water Quality In The East And Upper South Branches Of The Kishwaukee River Watershed (Esbkr), Ashley Irene Broussard

Graduate Research Theses & Dissertations

The East and Upper South Branches of the Kishwaukee River Watershed (ESBKR) are two HUC-10 watersheds that cover approximately 221.8 mi2 (574.5 km2) in north-central Illinois. Segments of the Kishwaukee River within the ESBKR are in the ILEPA’s 303(d) list of impaired waters for fish consumption and aesthetic quality. To protect and improve stream health, we must better understand the impact of diverse land use on non-point source (NPS) pollution and water quality. The primary goal of this study was to determine how different land uses impact the surface water quality within the ESBKR. To address this goal, surface water …

Dispossessed Again: Paiute Land Allotments In The Mono Basin, 1907-1929, Robert B. Marks

Eastern Sierra History Journal

Like most California Indians, the Kutzadika^a people in the Mono Basin on the east side of the Sierra Nevada Mountains were dispossessed of their land in the second half of the nineteenth century. However, they were not then removed to a reservation. They were left landless with no rights to reclaim their land until the Dawes Act (1887) made land allotments to non-reservation Indians possible. This article explores the history of land allotments in the Mono Basin, and places that story into the broader context of U.S. assimilationist policies but more importantly into the context of local history. Kutzadika …

Dynamics Of Flood Flow In Red River Basin, Vida Atashi

Theses and Dissertations

In recent decades, flooding has become a major issue in many areas of the Upper Midwest. Many rivers and streams in the region had considerable increases in mean annual peak flows during this period, which was driven by a combination of natural factors including discharge synchrony with the spring thaw, ice jams, glacial lake plain, and a decrease in gradient downstream. The Red River of the North is a prominent river in the United States and Canada's Upper Midwest. It flows from its headwaters in Minnesota and North Dakota to Lake Winnipeg in Manitoba. The river is well-known for its …

Evaluating The Impact Of Electricity And Electron Movement On The Electric Grid From Distributed Generation, Cooper R. Wade

Theses and Dissertations

The United States’ electric grid is currently undergoing a monumental energy transition involving the incorporation of new fuel sources, generation types, and operational modifications. Since 1920, the U.S. energy collective has been overseen by the Federal Energy Regulatory Commission (FERC), where during this tenure they have pursued the direct regulation of Distributed Energy Resources (DERs). This reasoning has been utilized over 300 times in federal cases and proceedings as the adoption rate of DERs has increased, which is based upon the language allowing the federal regulation of electricity based upon the flow of electrons. This is based solely upon the …

Employing Artificial Intelligence Methods In Drug Development: A New Era In Medicine, Omega John Unogwu, Mabel Ike, Opkanachi Omatule Joktan

Mesopotamian Journal of Artificial Intelligence in Healthcare

Artificial intelligence (AI) plays a vital role in the development of pharmaceuticals. The whole drug development process, from target identification and lead optimization to clinical trials and post-marketing monitoring, has the potential to be revolutionized by AI. Data analysis is a crucial area where AI thrives. To find trends, correlations, and prospective targets for therapeutic intervention, AI systems can analyse enormous volumes of data, including electronic health records, molecular databases, academic literature, and clinical trial data. This saves time and resources by enabling researchers to decide which compounds or pathways to investigate. Lead optimization is another area where AI is …

Novel Delivery Systems Of Curcumin And Resveratrol, Mohamed Salem Elfaruk

Electronic Theses and Dissertations

No abstract provided.

Development Of Probiotic Whipped Cream And Butter Using Whey Protein Hydrolysate-Encapsulated Probiotic Organisms, Kritika Gaba

Electronic Theses and Dissertations

No abstract provided.

Industry Update October 2022, Elaine Harris

Articles

Company news Bend Bioscience invests in expansion of drug-delivery capabilities Bend Bioscience (OR, USA) and NovaQuest Private Equity, have announced plans on 11 October 2022 to invest in a new facility in Bend, Oregon. The group will focus on developing new R&D partnerships, and early phase manufacturing and development activities based on proprietary particle engineering-based drug-delivery technologies. This new facility will consist of approximately 20,000 square feet of laboratory and processing areas and it is anticipated that manufacturing and analytical capabilities will operational by the end of Q2 2023. Announcing the investment decision, Dan Dobry, Bend Bioscience’s co-founder said “We …

Career Handbook, Unlv Career Services

Career Handbook

The job search can be daunting and intimidating, but you are not alone in this journey. As you move into the next stage of your professional career, we want you to know that you have the support of UNLV Career Services, the UNLV Alumni Association, and employers who are part of our Rebel Family. We are here to mentor, guide, and walk you through the job search process, and we are invested in your future.

The road to career success is not always as easy as we might hope. You may encounter setbacks and struggles throughout the next few years, …

One Last Month, Or Clancy's Time-Box, Safiyya Bintali

Calvert Undergraduate Research Awards

One Last Month is a young adult (YA) novella of roughly forty-three thousand words aimed at readers in middle school and in early high school grades. Structurally, it is an “ensemble Bildungsroman”, wherein all the main characters—rather than just one—embark on journeys of emotional growth and are given significant plot focus. Through the characters, One Last Month focuses on the importance and influence of non-romantic love, specifically through homosocial relationships between the novella’s male characters. It also touches on the process of grief beyond the Kübler-Ross structure and, though more subtly, emotional expression in young men. Through one of the …

Richard Owen: A Forgotten Icon, Devan Henriott

Calvert Undergraduate Research Awards

Despite being one of the most famous naturalists of the nineteenth century, Richard Owen is an obscure figure today. This paper delves into how such an influential person to the beginnings of paleontology and biology could have been written out of history. Owen worked his way into the world of comparative anatomy by finding work at the Hunterian Museum. From there, Owen earned respect for his exciting lectures on fossil discoveries and for his research interpreting fossils and reconstructing extinct species. Owen utilized his renown to spread his theories on the creations of species, but mostly kept his evolutionary ideas …

The Role Of Machine Learning And Network Analyses In Understanding Microbial Composition In An Experimental Prairie, Ali Eastman Oku

Graduate Research Theses & Dissertations

Machine learning and network analyses are powerful modern tools can process and map out connections between large amount of ecological data from complex environmental communities. Random forests, an ensemble machine learning algorithm, are particularly powerful as they can capture complex patterns in data while remaining easily interpretable. These tools are specifically useful in experimental settings where different types of data are collected. The aim of this study was to demonstrate the utility of machine learning models and network analyses at analyzing diverse ecological data from dynamic plant-soil microbial communities in a prairie ecosystem. Our experimental system is an experimental prairie …

Children's Evaluations Of Observable Vs. Unobservable Properties During Scientific Reasoning, Taneisha Vilma

Graduate Research Theses & Dissertations

Science inquiry involves reasoning and drawing conclusions about properties or constructs that may not be directly observed and are not immediately verifiable. Prior scientific reasoning investigations have examined children’s reasoning about observable items and immediately verifiable conclusions. The current investigation examined children’s evaluations of the certainty of conclusions drawn from evidence when reasoning about both immediately observable properties and unobservable properties with the same task. Kindergarten, first grade, third grade, and adult participants (N = 70) were presented with an online experimental procedure. The procedure included two conditions (Observable vs. Unobservable) each involved reasoning about three levels of evidence (conclusive …

The Discovery And Characterization Of Novel Potent 5-Substituted 3, 3’, 4’, 7-Tetramethoxyflavonoid Dna Triplex Specific Binding Ligands, Vanessa Marie Rangel

University of the Pacific Theses and Dissertations

Chemotherapy works by killing fast dividing cells. Unfortunately, these drugs are not specific to cancer tissue and can damage normal cells. Chemotherapy is like taking poison and hoping it kills the cancer cells before it kills you. As an alternative, many researchers have investigated the use of antigene therapy to selectively target cancer causing genes to avoid off target effects. Although promising, the theory is limited by the stability of the triplex structure. Here, we report the discovery of potent triplex binding ligands derived from the natural product quercetin. Chemical derivatives of 5-substituted 3, 3’, 4’, 7-tetramethoxyquercetin derivatives were characterized …

The Characteristics Of Senior Leadership Teams In High Performing Western Australian Catholic Composite And Secondary Schools, Daniel Michael Groenewald

Theses

The purpose of this research was to explore the perceptions of principals, senior leadership team members, and middle leaders regarding the characteristics of senior leadership teams (SLTs) in high-performing Catholic Education Western Australian composite and secondary schools (CCSS). The study investigated the characteristics that enhanced and inhibited SLTs. It explored the resources and professional learning that could improve SLTs and the role of the principal in the SLT. This research is the first study of SLTs in CCSS.

The study's literature review identified six areas of literature that formed the conceptual framework of this thesis. These six areas were: the …