Digital Commons Network^™

Methods For Chromatin Immunoprecipitation Of Biomphalaria Glabrata Nf-Κb, Marissa A. Zintel

Lawrence University Honors Projects

Biomphalaria glabrata is a species of freshwater snail that is an intermediate host to the parasite Schistosoma mansoni, a causative agent of human schistosomiasis. Substantial research has focused on the B. glabrata immune system, but progress is restricted by the limited molecular tools available for molluscan organisms. While many studies have described the anti-parasitic defenses of B. glabrata, the initiation and regulation of these defenses remain unclear. One important immune regulator, well known in both human and Drosophila immunology, is nuclear factor kappa B (NF-κB). Research has shown that B. glabrata NF-κB transcripts are upregulated in response to …

Gangliogenesis And Embryonic Development In Biomphalaria Glabrata, Subhiksha Srinivasan

Lawrence University Honors Projects

Biomphalaria glabrata is an intermediate host for a parasitic species, Schistosoma mansoni, which can infect humans causing schistosomiasis. The majority of research conducted on these snails focuses on host-parasite relationships. Thus, very little is known regarding their nervous system, especially during embryonic and juvenile development. This project aims to investigate the transition from the embryonic nervous system consisting of a network of neurons to a developed ganglionic nervous system consisting of a separation between clusters of nerve cell bodies, or ganglia, and connectives. To investigate when this process, known as gangliogenesis, occurs, immunofluorescence is used to visualize the serotonergic nervous …

Lipids And Lipoproteins May Play A Role In The Neuropathology Of Alzheimer’S Disease, Omer Akyol, Sumeyya Akyol, Mei-Chuan Chou, Shioulan Chen, Ching-Kuan Liu, Salih Selek, Jair C Soares, Chu-Huang Chen

Faculty, Staff and Student Publications

Alzheimer's disease (AD) and other classes of dementia are important public health problems with overwhelming social, physical, and financial effects for patients, society, and their families and caregivers. The pathophysiology of AD is poorly understood despite the extensive number of clinical and experimental studies. The brain's lipid-rich composition is linked to disturbances in lipid homeostasis, often associated with glucose and lipid abnormalities in various neurodegenerative diseases, including AD. Moreover, elevated low-density lipoprotein (LDL) cholesterol levels may be related to a higher probability of AD. Here, we hypothesize that lipids, and electronegative LDL (L5) in particular, may be involved in the …

Masthead

UC Law SF Journal on Gender and Justice

No abstract provided.

Critical Latino Studies: Combatting The (Mis)Education Of Latino Students In U.S. Public Schools, Heidi Kern

West Chester University Master’s Theses

In this thesis, I will explore the historical undervaluing and miseducation of Latino youth in U.S. public schools using a lens of decolonial theory to combat the systems of oppression that continue to affect our Latino youth today. First, I explain what experiences brought me to this concern and provide a clear theoretical framework to explain my philosophy of education. I also articulate key concepts from decolonial scholars and educational activists that inform my own work on the educational experiences of Latino students. In Chapter Three, I provide a historical review of how a public school system rooted in colonialism …

A Picture Is Worth A Thousand Words: Understanding Our Students' Mathematical Experiences Through Drawing, Gabriel T. Matney, Corrinne Fischer, Jack L. Jackson Ii

School of Inclusive Teacher Education Faculty Publications

Learning about our students’ perceptions of mathematics can help teachers better understand students’ mathematical efficacy and aid in the creation of lessons that foster positive mathematical learning experiences. In this article, we share some students’ perceptions of doing mathematics through their drawings. We looked at students from three different grade levels in three different countries: China, Fiji, and the United States. We discuss what we learned from these drawings as teachers and how teachers can use the drawing task to learn more about their student’s perceptions of doing mathematics.

Manipulation Of Components Of The Renin Angiotensin System In Renal Proximal Tubules Fails To Alter Atherosclerosis In Hypercholesterolemic Mice, Masayoshi Kukida, Naofumi Amioka, Dien Ye, Hui Chen, Jessica J. Moorleghen, Ching-Ling Liang, Deborah A. Howatt, Yuriko Katsumata, Motoko Yanagita, Hisashi Sawada, Alan Daugherty, Hong S. Lu

Saha Cardiovascular Research Center Faculty Publications

Background and objective: Whole body manipulation of the renin-angiotensin system (RAS) consistently exerts profound effects on experimental atherosclerosis development. A deficit in the literature has been a lack of attention to the effects of sex. Also, based on data with gene-deleted mice, the site of RAS activity that influences lesion formation is at an unknown distant location. Since angiotensin (AngII) concentrations are high in kidney and the major components of the RAS are present in renal proximal tubule cells (PTCs), this study evaluated the role of the RAS in PTCs in atherosclerosis development.

Methods and results: Mice with an LDL …

Trademark Tarnishmyths, Jake Linford, Justin Sevier, Allyson Willis

Scholarly Publications

Trademark law protects famous marks from dilution by tarnishment, defined by statute as use likely to "harm the reputation of the famous mark." Tarnishing uses are typically those that connect a mark with disreputable goods or topics, like sex or drugs. Mark owners worry that consumers will not purchase products connected with sexually explicit or drug-related materials, and courts often presume the same. If those associations likely cause consumers to withhold custom or dissipate goodwill consumers have invested in the mark, anti-tarnishment protection might be justified. But if that harm is more mythic than real, the law penalizing tarnishing use …

Review: Spencer Fluhman And Philip Barlow, Eds. The Book Of Mormon: Brief Theological Introductions. Provo, Ut: Neal A. Maxwell Institute, Brigham Young University, 2021., Seth Perry

Mormon Studies Review

“Theology” is a complicated concept in Mormon discourse. It is routine to say that there is no tradition of formal Mormon theology, or even any Mormon theology at all. This is explained by observing that continuing revelation and the multiple genres of Mormon scripture resist systematization, or that the Church of Jesus Christ of Latter-day Saints eschews seminaries and professionalized clergy. Both the perceived need and the space for discussion of what other Christianities consider theological questions is thought to be constrained by institutional and cultural insistence on the prophetic authority of church leaders. Seminarians are not needed to work …

Review: Blaire Ostler. Queer Mormon Theology: An Introduction. Newburgh, In: By Common Consent Press, 2021., Mees Tielens

Mormon Studies Review

In Queer Mormon Theology: An Introduction, Blaire Ostler straddles the boundaries between scholar and memoirist, queer and woodcuts by the artist Brian Kershisnik, and inside they are evocatively illustrated, with vivid orange accents and creative layout. In Miller’s volume, the verses of Mormon 6:8–22 are sparsely printed in white, a few lines at a time, across sixteen otherwise black pages. It feels, indeed, like the end of a world.

Review: Michael L. Tate, Ed. The Great Medicine Road: Narratives Of The Oregon, California, And Mormon Trails, Part 4: 1856–1869. Edited With The Assistance Of Kerin Tate, Will Bagley, And Richard L. Rieck. Norman, Oklahoma: The Arthur H. Clark Company, An Imprint Of The University Of Oklahoma Press, 2020., Juliette Bourdin

Mormon Studies Review

The four-volume series The Great Medicine Road offers a collection of primary sources about the overland trails across the American West in the nineteenth century. Originally designed by Will Bagley, a leading expert on trails history, and Richard L. Rieck, a professor of geography, the project was carried out by Michael L. Tate, a professor of history emeritus at the University of Nebraska, Omaha. The first volume, published in 2014, included fifteen sources for the period 1840–1848, encompassing the early years of migration on the overland trails. The second volume Smith’s path, a woman with her man following her lead. …

Parental Instincts: The Neurological And Biological Factors Associated With Parenthood, Jared Reeder

Undergraduate Honors Theses

The following project involves a systematic review of the scientific literature on neural and biological changes of mothers and fathers in parenthood. Until very recently, little scientific research was devoted to studying how bearing children affects a man or woman’s long-term biology. Over the last twenty years, studies of neuroplastic changes in new mothers show specific neural mechanisms responsible for altering the behaviors of mothers during and after pregnancy. These changes in neuroplasticity alter behavior in such a way that led to mothers requiring less sleep and being more prone to hearing the cries of their children. In addition to …

Lipophilic Analogues Of D-Cysteine Prevent And Reverse Physical Dependence To Fentanyl In Male Rats., James N Bates, Paulina M Getsy, Gregory A Coffee, Santhosh M Baby, Peter M Macfarlane, Yee-Hsee Hsieh, Zackery T Knauss, Jason A. Bubier, Devin Mueller, Stephen J Lewis

Faculty Research 2024

We examined whether co-injections of the cell-permeant D-cysteine analogues, D-cysteine ethyl ester (D-CYSee) and D-cysteine ethyl amide (D-CYSea), prevent acquisition of physical dependence induced by twice-daily injections of fentanyl, and reverse acquired dependence to these injections in freely-moving male Sprague Dawley rats. Injection of the opioid receptor antagonist, naloxone HCl (NLX, 1.5 mg/kg, IV), elicited a series of withdrawal phenomena that included cardiorespiratory and behavioral responses, and falls in body weight and body temperature, in rats that received 5 or 10 injections of fentanyl (125 μg/kg, IV), and the same number of vehicle co-injections. Regarding the development of physical dependence, …

Newsletter 2023, Department Of Parasitology Faculty Of Medicine

Archival Material (2020s)

No abstract provided.

Courtroom Presentation Technology_ Avoiding Death By Powerpoint, Indiana Continuing Legal Education Forum (Iclef)

Indiana Continuing Legal Education Forum 2023

Meeting proceedings of a seminar by the same name, held August 15, 2023.

2023 Advanced Worker's Compensation, Indiana Continuing Legal Education Forum (Iclef)

Indiana Continuing Legal Education Forum 2023

Meeting proceedings of a seminar by the same name, held March 22, 2023.

The Use Of Artificial Intelligence In The Practice Of Law, Indiana Continuing Legal Education Forum (Iclef)

Indiana Continuing Legal Education Forum 2023

Meeting proceedings of a seminar by the same name, held August 4, 2023.

Evidence For Trial Lawyers, Indiana Continuing Legal Education Forum (Iclef)

Indiana Continuing Legal Education Forum 2023

Meeting proceedings of a seminar by the same name, held November 14, 2023.

Advanced Cybersecurity_ Protecting The Store For Your Business Client, Indiana Continuing Legal Education Forum (Iclef)

Indiana Continuing Legal Education Forum 2023

Meeting proceedings of a seminar by the same name, held July 27-28, 2023.

A Deep Dive Into The Ucc, Indiana Continuing Legal Education Forum (Iclef)

Indiana Continuing Legal Education Forum 2023

Meeting proceedings of a seminar by the same name, held December 12, 2023.

Tintoretto: Painting In The Chaotic Reformations, Summer Markham

OUR Journal: ODU Undergraduate Research Journal

The following essay investigates Tintoretto’s, a Venetian artist during the 16^th century, artist techniques in his painting the Last Supper and how the period is reflected within it. For instance, the chiaroscuro and sfumato techniques in the painting are used to allude the darkness surrounding the self-indulgence, financial abuses, and religious corruption during the Counter-Reformation. Research of underlying symbolism and historical events further reveal how the Last Supper reflects the dark, confusing time that Europe was in during the Counter-Reformation. Understanding the Last Supper and understanding it’s historical context aids in the ability to observe the emotions during that …

Prosaas And Neurodegenerative Diseases, Cydney Battle

OUR Journal: ODU Undergraduate Research Journal

Neurodegenerative diseases such as Alzheimer’s disease, prion diseases, Huntington’s disease, and Parkinson’s disease undeniably wreak havoc on the system of the body. The catastrophic effects of neurodegenerative diseases are felt by the reality of being incurable and the resulting effect of the progressive degeneration of the individual’s physical and mental stature. Through continuous research, experimentation, and an understanding of how neurodegenerative diseases develop and function, scientific tactics against the development and progression of these diseases will be uncovered. The abnormal aggregation of proteins is largely attributed to the development of neurodegenerative diseases. In the instance of abnormal protein aggregation, the …

Exploring The Use Of Digital Technologies In Early Childhood Teacher Education: A Case Of A Core Primary Teachers’ College In Uganda., Richard Anywar

Master of Education

This qualitative case study interrogated the use of digital technologies in Tera CPTC (pseudonym) in Northwestern Uganda under three research questions, namely: (1) What are the digital technologies teacher educators use to improve ECTE at Tera (pseudonym) CPTC? (2) How do teacher educators use digital technologies to improve Early Childhood Teacher Education? (3) What challenges do the ECE teacher educators face with the use of digital technologies to improve teaching and learning at Tera CPTC? Data was collected using classroom observation, focus group discussion, and semi-structured interviews. Three tutors and twenty-four teacher trainees participated in the study. Study findings revealed …

Exploring How Advanced-Level Biology Teachers Integrate Ict In Teaching And Learning,A Case Of One Public Secondary School In Songwe Region, Tanzania, Rose John Shiyo

Master of Education

Information and Communications Technology (ICT) has pedagogical advantages that can help teachers design, teach, and assess biology lessons. The aim of this study was to explore how teachers integrate ICT during the teaching of Biology at A-level classes in Songwe region, Southern Tanzania. The research site of this study is one public advanced-level secondary school in the Mbozi district. The purposive sampling technique was used to get the sample comprising two, A-level biology teachers, one ICT technician, one laboratory technician, and six students from A-level classes who were persuing a science subject combination known as CBG (Chemistry Biology Geography). This …

Livestock Management In 2023 - 2024, Department Of Primary Industries And Regional Development, Western Australia

Animal production and livestock published reports

Parts of WA have experienced below average rainfall resulting in feed limitations, with below average rainfall also predicted for the coming months. The feed shortage has been further compounded by limited slaughter space and reduced market prices for sheep.

Sheep industry economist, John Young, of Farming Systems Analysis Service was commissioned to look at the economics of some key decisions this season, taking into account current seasonal and market conditions.

WA sheep producers need to have plans in place early to monitor stock condition and make decisions about which classes of stock to keep. This will also include the feed …

How Do I Grow Tedera?, Daniel Real

Animal production and livestock published reports

The issue:

Livestock producers are faced with climate variability challenges and rising input costs while trying to maximise livestock productivity and profitability.

The impact:

Traditional or older pasture systems can limit production due to poor performance in dry periods or shorter production windows.

The opportunity:

Tedera is a resilient legume pasture that can fill feed gaps at a lower cost while offering livestock productivity gains.

Tedera: A Guide To Growing And Utilising This Perennial Pasture Legume, Daniel Real

Animal production and livestock published reports

The commercial release of a new pasture species is a rare and, potentially, important event. In the case of tedera (Bituminaria bituminosa var. albomarginata) we have a novel perennial pasture legume with characteristics which set it apart from anything currently available to growers in Australia or internationally.

Specifically, it is a drought-tolerant, highly productive perennial pasture with the capacity to provide nutritious forage, especially when other feed sources are scarce. Its reaction to drought is in contrast with the few successful perennial legumes available for Mediterranean climatic zones, such as lucerne, as it retains green leaves when water stressed, allowing …

Deep Ecology, Nature Spirits, And The Filipino Transpersonal Worldview, Carl Lorenz Cervantes

International Journal of Transpersonal Studies

Many Filipinos today still believe that the world is filled with invisible entities who can affect their lives in a tangible way. These beings usually reside in nature as the souls of ancestors or other mysterious spirits. This indigenous transpersonal worldview implies that the individual is part of a living world. The modern term “deep ecology” seems to be aligned with this worldview. This paper looks at the implications of the Filipino transpersonal worldview on policies related to the care for environment and biodiversity.

2022 Annual Report Of The Town Of Candia, New Hampshire, Town And School District Reports For The Year Ending December 31, 2022., Candia Town Representatives

Candia, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Simplifying Blood Pressure Measurements In Clinical Settings, Uwe Reischl, Conrad Colby

Public and Population Health Faculty Publications and Presentations

Background: Upper arm sphygmomanometry is the most commonly used method to measure blood pressure in adults. However, variations in upper arm circumference and use of different cuff-sizes results in different pressure readings. When using the same cuff size, pressure readings will be higher for larger arm circumferences and lower for smaller arm circumferences. The objective of this study was to identify an adjustment factor that will allow pressure readings obtained for any combination of arm circumference and cuff size to be compared.

Methods: To investigate the relationship between arm circumferences, cuff size and pressure readings, experiments were conducted using laboratory …