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“These Different Ideas, Traditions, And Values Make My Thinking Unique And Creative”: Bringing Native Hawaiian Ways Of Knowing To Engineering Education, Austin Morgan Kainoa Peters, Susan M. Lord

School of Engineering: Faculty Scholarship

Contribution: This article focuses on the study of Native Hawaiian student experiences in engineering education. Telling these stories illustrates the importance of legitimizing and appreciating different knowledge types in engineering as we move toward a more inclusive and sustainable field. Background: Native Hawaiian engineering students live oppressive realities due to the history of settler colonialism and occupation that attempted to erase their culture and ways of knowing, including in engineering education. This study shows how students overcome these realities to enact their ways of knowing in a field where it is not always respected. Informing the field of ways to …

Addressing Multilingual Learners’ Language Needs Through Engaging Inquiry-Based Science, Viviana Alexandrowicz, Bobbi Hansen

School of Leadership and Education Sciences: Faculty Scholarship

This article presents an overview of a 3-year series of workshops on teaching and providing multilingual learners (MLs) with access to science by utilizing effective language development strategies. The workshops were delivered to primary teachers in California and included three different modules: (a) Think and Question Like a Scientist, (b) Observe and Record Like a Scientist through Science Notebooking, and (c) Argue Like a Scientist. The activities showcase effective, research-based second language acquisition (SLA) strategies, including providing comprehensible input via paraphrasing, using visual and media resources, gestures, and the student’s native language, and modeling tasks. Additionally, scaffolding academic language through …

Barriers To And Facilitators Of Military Spouses’ Recovery From Perinatal Mental Health Disorders: A Qualitative Study, My Hanh (Theresa) Nguyen, Semira Semino-Asaro, Alison M. Reminick, Amber T. Rukaj, Cynthia D. Connelly

School of Nursing and Health Science: Faculty Scholarship

Introduction: Perinatal mental health disorders (PMHDs) are a common complication of child-bearing, affecting approximately 1 in 7 U.S. mothers. An expanding literature has examined how PMHDs afect military families; however, little is known about military spouses’ experiences in accessing and engaging in treatment for PMHDs. Te purpose of this qualitative study was to gain a better understanding of the barriers to and facilitators of accessing, engaging, and progressing in treatment and recovery among a sample of U.S. military spouses with PMHDs. Methods: Military spouses (N = 12) were recruited from a maternal mental health clinic at an academic …

Improving Patient-Reported Outcomes In Stroke Care Using Remote Blood Pressure Monitoring And Telehealth, Imama Naqvi, Kevin Strobino, Hanlin Li, Kevin Schmitt, Yuliya Barratt, Stephen A. Ferrara, Amna Hasni, Kenrick D. Cato, Mark G. Weiner, Mitchell S. V. Elkind, Ian M. Kronish, Adriana Arcia

School of Nursing and Health Science: Faculty Scholarship

Background Inequities in health care access leads to suboptimal medication adherence and blood pressure (BP) control. Informatics-based approaches may deliver equitable care and enhance self-management. Patient-reported outcomes (PROs) complement clinical measures to assess the impact of illness on patients' well-being in poststroke care.

Objectives The aim of this study was to determine the feasibility of incorporating PROs into Telehealth After Stroke Care (TASC) and to explore the effect of this team-based remote BP monitoring program on psychological distress and quality of life in an underserved urban setting.

Methods Patients discharged home from a Comprehensive Stroke Center were randomized to TASC …

Annual Report For The Town Of Alexandria For The Fiscal Year Ending December 31, 2022., Alexandria Town Representatives

Alexandria, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

An Intravenous Pancreatic Cancer Therapeutic: Characterization Of Crispr/Cas9n-Modified Clostridium Novyi-Non Toxic, Kaitlin M. Dailey, James M. Small, Jessica E. Pullan, Seth Winfree, Krysten E. Vance, Megan Orr, Sanku Mallik, Kenneth W. Bayles, Michael A. Hollingsworth, Amanda E Brooks

Journal Articles: Pathology and Microbiology

Clostridium novyi has demonstrated selective efficacy against solid tumors largely due to the microenvironment contained within dense tumor cores. The core of a solid tumor is typically hypoxic, acidic, and necrotic-impeding the penetration of current therapeutics. C. novyi is attracted to the tumor microenvironment and once there, can both lyse and proliferate while simultaneously re-activating the suppressed immune system. C. novyi systemic toxicity is easily mitigated by knocking out the phage DNA plasmid encoded alpha toxin resulting in C. novyi-NT; but, after intravenous injection spores are quickly cleared by phagocytosis before accomplishing significant tumor localization. C. novyi-NT could be designed …

Comparing The Performance Of A Targeted Pull-Down Assay To Shotgun Sequencing For Improving Respiratory Infectious Disease Surveillance, Monica R. Christian

Browse all Theses and Dissertations

Current surveillance focuses on well characterized pathogens such as influenza. Since 2000, there have been multiple outbreaks of respiratory disease. These outbreaks have demonstrated the need for robust and collaborative global efforts to identify, monitor, and contain novel respiratory viruses. This study aims to improve the ability of public health agencies to monitor and respond to respiratory disease outbreaks. Using five respiratory pathogens, this study compares a molecular capture technology from Twist Biosciences to the shotgun sequencing approach of whole transcriptome amplification (WTA, Qiagen) with the goal of determining which method is most effective using cost, usability, and sequencing quality …

Incorporating Genomic Analysis In The Clinical Practice Of Hepatology, David Hun Chung

Yale Medicine Thesis Digital Library

In the past two decades, whole-exome sequencing has been successfully demonstrated as an indispensable instrument in uncovering the genetic etiology underlying numerous types of unexplained liver disease. Characterization of these illnesses into distinct molecular disease entities has revolutionized understanding of pathophysiology and has translated into improved guidance on management, treatment and prognosis for patients. However, hepatologists have been slow to welcome the technology into their mainstream clinical practice, largely due to inadequate training in genomic medicine. There thus remains a pressing need to create various forums through which clinicians can gain better appreciation for the value of genetic analysis in …

Nontyphoidal Salmonella Causing Mycotic Aneurysms And Subsequent Vascular Graft Infection: A Case Report, Bernard Dankyi, Sandi Dunn, Zainab Saeed, Vincent Santi, Aneta Tarasuik Rusek

North Florida Division GME Research Day 2023

No abstract provided.

Review Of The International Play Policies And Their Contribution To Supporting A Child's Right To Play, Fiona Armstrong, David Gaul

Articles

Play is recognised as a fundamental children's right protected by the United Nations Convention on the Rights of the Child. Despite legal and constitutional requirements for ensuring children's right to play, there are few international policies dedicated to play. This paper seeks to use a critical discourse analysis lens to compare the current international policies dedicated to play and identify examples of good practice and perceived barriers to the successful development and implementation of play policies.

Parnassus 2023

Parnassus

The 2023 edition of the student literary journal, Parnassus, published by Taylor University in Upland, Indiana.

Sanctions And Consequences: Third-State Impacts And The Development Of International Law In The Shadow Of Unilateral Sanctions On Russia, Avidan Cover

Faculty Publications

In response to Russia’s invasion of Ukraine, NATO member states and their allies have imposed “unprecedented,” unilateral economic sanctions to hold Russia accountable, degrade its military capability, and limit its international financial access.1 From the outset, sanctioning states such as the United States have stated that they “designed these sanctions to maximize the long-term impact on Russia and to minimize the impact on [themselves and their] allies.”2 These sanctions on an economic power like Russia “have global economic effects far greater than anything seen before.”3 And there is concern that the unintended consequences of the sanctions will disproportionately harm developing …

2023 Annual Report, Tennessee. Division Of Forestry And Tennessee. Department Of Agriculture

Forestry Annual Reports

This annual report presents an overview of Tennessee Forestry Commission programs and management.

Annual Report Of The Wally Cordes Teaching And Faculty Support Center For The Year Ended...2023, University Of Arkansas, Fayetteville. Wally Cordes Teaching And Faculty Support Center

Wally Cordes Teaching and Faculty Support Center Annual Report

No abstract provided.

Characteristics Of Gingival Crevicular Fluid Flow During Orthodontic Treatment With Invisalign, Nina Stevens

Orthodontics and Endodontics Theses

OBJECTIVES. Studies on quantitative relationships between magnitude of force applied to a tooth root and formation of gingival crevicular fluid (GCF) biomarkers (volume, concentrations of cytokines, enzymes, etc.) in clinical settings are lacking. This study aims to answer the question: What can analysis of GCF flow dynamic characteristics inform us about orthodontic tooth movement in a patient treated by Invisalign? METHODS. In three participants, two GCF samples were collected from five maxillary and five mandibular teeth during start, middle and end of Invisalign treatment. Plaque index and pocket depths were determined. Periopaper strips (Oraflow) were used for collection of GCF, …

Contents And Editor's Forward, Rachel A. Walsh

International ResearchScape Journal

No abstract provided.

Pioneers, Parricides, And The Spectre Of Violence In Settler-Colonial Homes And Histories, Katrina Jagodinsky

Department of History: Faculty Publications

Americans are grappling with everyday political and personal violence on a variety of fronts. Escalating frustrations with alternating police inaction and violence, failed explanations of gender- and racially motivated mass-shootings, and the heartbreaking centrality of children in this violence—as both victims and perpetrators—leave many onlookers desperate to understand how these acts have come to be so distinctly American. A cadre of scholars are focused on this problem: criminologists, lawyers, political scientists, psychologists, sociologists, and, applying their own unique set of tools and methodologies, historians. Among the historians concerned with the peculiarities of American violence are those who specialize in the …

Yale School Of Medicine Facts & Figures 2023-2024, Yale School Of Medicine Office Of Communications

Facts & Figures – annual Yale School of Medicine numbers

Provided by the Office of Communications, the Facts and Figures brochure is produced annually as a way to provide a snapshot of key facts and data related to the School of Medicine as well as the Medical Campus. This includes enrollment data, research activity, financial summaries, and more.

Profiles Of Circumscribed Interests In Autistic Youth, Emily Spackman, Luke D. Smillie, Thomas Frazier, Antonio Y. Hardan, Gail A. Alvarez, Andrew Whitehouse, Mirko Uljarević

2023 Faculty Bibliography

Circumscribed interests (CI) encompass a range of different interests and related behaviors that can be characterized by either a high intensity but otherwise usual topic [referred to as restricted interests (RI)] or by a focus on topics that are not salient outside of autism [referred to as unusual interests (UI)]. Previous research has suggested that there is pronounced variability across individuals in terms of the endorsement of different interests, however, this variability has not been quantified using formal subtyping approaches. Therefore, using Latent Profile Analysis in a sample of 1,892 autistic youth (Mage = 10.82, SDage = 4.14; 420 females), …

The U.S. Cable Televisions' Framing Of Mass Shooting: A Grounded Discovery Of Competing Narratives, Maurice Emelu

2023 Faculty Bibliography

News frames play a vital role in shaping the audience's interpretation of the news, their participation in policy discussions, and their engagement in public discourse. This study uses the Analysis of Topic Model Networks (ANTMA) frame analysis grounded approach and examines the 2017 Sutherland Springs, Texas, mass shooting coverage in a house of worship by three U.S. cable television networks—CNN, Fox News, and MSNBC. News reports for the first seven days following the shooting were collected from the cable networks' Twitter, YouTube, and website accounts. A total of 290 news reports were analyzed and 760 aggregate units for frames were …

Did Jewish Women Circumcise Male Infants In Antiquity? A Reassessment Of The Evidence, Thomas R. Blanton Iv

2023 Faculty Bibliography

Two diametrically opposed assumptions have influenced interpretations of circumcision rituals in ancient Judaism: either women performed the operation on their infant sons because children at birth and during infancy remained under the purview of the mother; or, conversely, men—specifically a ritual agent known as the mohel—performed circumcisions, because only they were typically granted authority to carry out the ritual. This study reassesses the pertinent texts, including Exodus 4 and passages from the books of Maccabees and the Babylonian Talmud (b. Šabb. 134a; b. Yebam. 64b; b. ʿAbod. Zar. 27a), to determine whether women in ancient Judaism may have circumcised their …

Protected Areas Slow Declines Unevenly Across The Tetrapod Tree Of Life, A Justin Nowakowski, James I. Watling, Alexander Murray, Jessica L. Deichmann, Thomas S. Akre, Carlos L. Muñoz Brenes, Brian D. Todd, Louise Mcrae, Robin Freeman, Luke O. Frishkoff

2023 Faculty Bibliography

Protected areas (PAs) are the primary strategy for slowing terrestrial biodiversity loss. Although expansion of PA coverage is prioritized under the Convention on Biological Diversity, it remains unknown whether PAs mitigate declines across the tetrapod tree of life and to what extent land cover and climate change modify PA effectiveness1,2. Here we analysed rates of change in abundance of 2,239 terrestrial vertebrate populations across the globe. On average, vertebrate populations declined five times more slowly within PAs (−0.4% per year) than at similar sites lacking protection (−1.8% per year). The mitigating effects of PAs varied both within and across vertebrate …

Linking Predator Responses To Alkaloid Variability In Poison Frogs Language:, J P. Lawrence, Bibiana Rojas, Annelise Blanchett, Ralph Saporito, Johanna Mappes, Antoine Fouquet, Brice P. Noonan

2023 Faculty Bibliography

Many chemically-defended/aposematic species rely on diet for sequestering the toxins with which they defend themselves. This dietary acquisition can lead to variable chemical defenses across space, as the community composition of chemical sources is likely to vary across the range of (an aposematic) species. We characterized the alkaloid content of two populations of the Dyeing Poison Frog (Dendrobates tinctorius) in northeastern French Guiana. Additionally, we conducted unpalatability experiments with naive predators, Blue Tits (Cyanistes caeruleus), using whole-skin secretion cocktails to assess how a model predator would respond to the defense of individuals from each population. While there was some overlap …

Maternal Chemical Defenses Predict Ofspring Defenses In A Dendrobatid Poison Frog, Olivia L. Brooks, Jessie J. James, Ralph Saporito

2023 Faculty Bibliography

Within and among populations, alkaloid defenses of the strawberry poison frog (Oophaga pumilio) vary spatially, temporally, and with life history stage. Natural variation in defense has been implicated as a critical factor in determining the level of protection aforded against predators and pathogens. Oophaga pumilio tadpoles sequester alkaloids from nutritive eggs and are, thus, entirely dependent on their mothers for their defense. However, it remains unclear how tadpole alkaloid composition relates to that of its mother and how variation in maternally provisioned defenses might result in varying levels of protection against predators. Here, we demonstrate that natural variation in the …

Development Of Informant-Report Neurobehavioral Survey Scales For Pten Hamartoma Tumor Syndrome And Related Neurodevelopmental Genetic Syndromes, Thomas Frazier, Robyn M. Busch, Patricia Klaas, Katherine Lachlan, Shafali Jeste, Alexander Kolevzon, Eva Loth, Jacqueline Harris, Leslie Speer, Tom Pepper, Kristin Anthony, J Michael Graglia, Christal Delagrammatikas, Sandra Bedrosian-Sermone, Jenine Beekhuyzen, Constance Smith-Hicks, Mustafa Sahin, Charis Eng, Antonia Y. Hardan, Mirko Uljarevic

2023 Faculty Bibliography

There are few well-validated measures that are appropriate for assessing the full range of neurobehavioral presentations in PTEN hamartoma tumor syndrome (PHTS) and other neurodevelopmental genetic syndromes (NDGS). As potential therapeutics are developed, having reliable, valid, free, and easily accessible measures to track a range of neurobehavioral domains will be crucial for future clinical trials. This study focused on the development and initial psychometric evaluation of a set of freely available informant-report survey scales for PHTS-the Neurobehavioral Evaluation Tool (NET). Concept elicitation, quantitative ratings, and cognitive interviewing processes were conducted with stakeholders and clinician-scientist experts, used to identify the most …

The Emma Cole Grand Rapids Flora Project: Documenting And Assessing Change 123 Years Later, Elliott Stob, Renee Figueroa, Garrett Crow, David Warners

Summer Research

In 1901, botanist, teacher, and Kent Scientific Institute scientist, Emma J. Cole published her book Grand Rapids Flora: A Catalogue of the Flowering Plants and Ferns Growing Without Cultivation in the Vicinity of Grand Rapids, Michigan. For over 100 years her book has provided an excellent perspective into the natural environment of the area. The aim of the project is to revisit and inventory sites she explored, as well as other remnant natural areas, to see how plant life has changed over the past 120+ years.

Beginning in 2015 the project has assessed 54 sites, mentored 19 students, discovered …

Concussion-Related Disruptions To Hub Connectivity In The Default Mode Network Are Related To Symptoms And Cognition, Heather C. Bouchard, Kate L. Higgins, Grace Amadon, Julia M. Laing-Young, Arthur C. Maerlender, Seima Al-Momani, Maital Neta, Cary R. Savage, Douglas H. Schultz

Center for Brain, Biology, and Behavior: Faculty Publications

Concussions present with a myriad of symptomatic and cognitive concerns; however, the relationship between these functional disruptions and the underlying changes in the brain are not yet well understood. Hubs, or brain regions that are connected to many different functional networks, may be specifically disrupted after concussion. Given the implications in concussion research, we quantified hub disruption within the default mode network (DMN) and between the DMN and other brain networks. We collected resting-state functional magnetic resonance imaging data from collegiate student-athletes (n = 44) at three timepoints: baseline (prior to beginning their athletic season), acute post-injury (approximately 48 hours …

Face Coverings Differentially Alter Valence Judgments Of Emotional Expressions, Nicholas R. Harp, Andrew T. Langbehn, Jeff T. Larsen, Paula M. Niedenthal, Maital Neta

Department of Psychology: Faculty Publications

Face masks that prevent disease transmission obscure facial expressions, impairing nonverbal communication. We assessed the impact of lower (masks) and upper (sunglasses) face coverings on emotional valence judgments of clearly valenced (fearful, happy) and ambiguously valenced (surprised) expressions, the latter of which have both positive and negative meanings. Masks, but not sunglasses, impaired judgments of clearly valenced expressions compared to faces without coverings. Drift diffusion models revealed that lower, but not upper, face coverings slowed evidence accumulation and affected differences in non-judgment processes (i.e., stimulus encoding, response execution time) for all expressions. Our results confirm mask-interference effects in nonverbal communication. …

A Long‐Term Obesogenic High‐Fat Diet In Mice Partially Dampens The Anti‐Frailty Benefts Of Late‐Life Intermittent Fasting, Yoko Henderson, Nazmin Bithi, Jie Yang, Christopher Link, Aili Zhang, Benjamin Baron, Eran Maina, Christopher Hine

Senior Honors Projects

The global obesity pandemic coupled with ever-growing life expectancies equates to hundreds of millions of individuals with potentially longer but not healthier lives. Aging is one of the risk factors for numerous maladies such as metabolic dis- order and frailty, which are exacerbated under obesity. Thus, therapeutic approaches that address obesity to ultimately improve afected individuals’ quality of life and extend their lifespan are needed. We previously reported that the every other day (EOD) fasting initiated late-life improved metabolic, musculoskeletal, and cognitive endpoints in standard rodent diet-fed mice. In the present study, using the same dietary intervention methodology, we tested …

Bacteria Commonly Associated With Central Nervous System Catheter Infections Elicit Distinct Csf Proteome Signatures, Matthew K. Beaver, Dragana Noe, Ishwor Thapa, Hesham Ali, Jessica Snowden, Tammy Kielian, Gwenn Skar

Journal Articles: Pathology and Microbiology

Background: Cerebrospinal fluid (CSF) shunt infection is a common and devastating complication of the treatment of hydrocephalus. Timely and accurate diagnosis is essential as these infections can lead to long-term neurologic consequences including seizures, decreased intelligence quotient (IQ) and impaired school performance in children. Currently the diagnosis of shunt infection relies on bacterial culture; however, culture is not always accurate since these infections are frequently caused by bacteria capable of forming biofilms, such as Staphylococcus epidermidis, Cutibacterium acnes, and Pseudomonas aeruginosa resulting in few planktonic bacteria detectable in the CSF. Therefore, there is a critical need to identify a …