Digital Commons Network^™

Characterizing And Epitope Mapping Single-Domain Antibodies On Borrelia Burgdorferi Protein Ospa, Saiful Basir

Legacy Theses & Dissertations (2009 - 2024)

Epitope mapping a protein that enables pathogenesis is crucial for the development of therapies and prophylactics that can inhibit the pathogen’s function and its transmission of disease. The lipoprotein OspA enables Lyme Disease etiologic pathogen, Borrelia burgdorferi, to inhabit the tick midgut until transmission occurs. Anti-OspA mAbs and their smaller VHH counterparts are highly specific and tailored to bind proteins such as OspA, reproducibly, at established binding sites or epitopes. Previous studies found an array of mAbs that successfully bound OspA and have already been used in epitope mapping. To our knowledge, this is the first use of VHHs in …

Probabilistic Forecasting Of Winter Mixed Precipitation Types In New York State Utilizing A Random Forest, Brian Chandler Filipiak

Legacy Theses & Dissertations (2009 - 2024)

Operational forecasters face a plethora of challenges when making a forecast; they must consider multiple data sources ranging from radar and satellites to surface and upper air observations, to numerical weather prediction output. Forecasts must be done in a limited window of time, which adds an additional layer of difficulty to the task. These challenges are exacerbated by winter mixed precipitation events where slight differences in thermodynamic profiles or changes in terrain create different precipitation types across small areas. In addition to being difficult to forecast, mixed precipitation events can have large-scale impacts on our society.

Applications Of Search And Matching To International Trade And Unemployment Insurance, Kai You

Legacy Theses & Dissertations (2009 - 2024)

This dissertation consists of three chapters.

Essays On Career Progression Among The Underrepresented In Academic Biomedicine, Allison Nunez

Legacy Theses & Dissertations (2009 - 2024)

Representation of women and minorities in academia has historically lagged behind their white, male counterparts at all levels, from student to tenured professor. An important milestone in this progression in the biomedical sciences is the achievement of last authorship, which serves as a proxy for career independence. This work investigates gender gaps in last authorship using population-level data on biomedical publications, and further considers how these gaps may be a result of different rates of progression through the early career process. Additionally, the role a like-gender mentor can play in early career productivity and progress toward that important milestone is …

Impact Of Eocene-Oligocene Antarctic Glaciation On The Paleoceanography Of The Weddell Sea, Victoria Hojnacki, Allison Lepp, Josie Horowitz Castaldo, Abbey States, Xiaona Li, Sandra Passchier

Department of Earth and Environmental Studies Faculty Scholarship and Creative Works

The Eocene-Oligocene Transition (EOT) at ∼34 Ma marked a climatic shift from greenhouse to icehouse conditions, toward long-lasting lower global temperatures and a continental ice sheet in the Antarctic. We report on sedimentological and inorganic geochemical results across the EOT at Ocean Drilling Program (ODP) Site 696 in the Weddell Sea, within the Antarctic limb of the Atlantic circulation. The geochemical composition of detrital, authigenic and biogenic marine sediment components, and sortable silt proxies demonstrate the impact of ice growth on high latitude water masses. Sortable silt grain size and Zr/Rb ratios attest to a period of vigorous circulation at …

Return Of The Yellow Peril? Racism, Xenophobia And Bigotry Against Asian Americans, Jonghyun Lee

Bridgewater Review

No abstract provided.

Tiny Tusks Breastfeeding And Infant Support: Breastfeeding's Effects On Maternal Mental Health, Anna Jacobs

The Eleanor Mann School of Nursing Undergraduate Honors Theses

Breastfeeding has proven to be beneficial for infant health and maternal physical health, but there are variable outcomes for maternal mental health. This literature review explores the relationship between breastfeeding and maternal mental health, a topic that is often disregarded when discussing breastfeeding with mothers. After an internship with Tiny Tusks Breastfeeding and Infant Support, a program to make breastfeeding more accessible at Razorback Athletics events, maternal mental health related to breastfeeding was shown to be a topic in need of more current research. This objective of this literature review was to determine how breastfeeding can impact maternal mental health …

Health Care Transition Experiences Of Youth With Intellectual Disabilities In A Post-Secondary Inclusive Program, Faith Duensing

The Eleanor Mann School of Nursing Undergraduate Honors Theses

Between the ages of 18-21 years old, youth and young adults make the transition from pediatric to adult health care. While it may be an easy and seamless transition for some, that is not always the case, especially for youth and young adults with disabilities. Youth with disabilities experience several distinct health disparities compared to their peers without disabilities and these can be carried over to impact their health care transition (HCT) process. The purpose of this study was to learn more about the HCT experiences of young adults with disabilities and their families to learn and develop ways that …

Fair + Equitable December 2022, International Association Of Assessing Officers

Fair + Equitable

The December 2022 issue cover story delves into cybersecurity, featuring lessons learned by a county after it was hacked.

Welcome Address, Michael A. Adebiyi

Economic and Financial Review

This is the Welcome Address presented by the Director of Research, Central Bank of Nigeria during the 28th Edition of the CBN Executive Seminar held at Transcorp Hilton, Abuja. The year’s theme: ‘Digitalisation of Money and Monetary Policy in Nigeria’ was motivated by the need to keep pace with monetary policy design and implementation in the digital age.

Digital Currencies: Emerging Trends, Challenges And The Future Of The Monetary System, Ngozi E. Egbuna

Economic and Financial Review

This paper discusses the nature and types, trends, prospects and benefits, challenges and demerits of digital currencies, as well as, the link between digital currencies and the monetary system.

Keynote Address, Godwin I. Emefiele Con

Economic and Financial Review

This is the keynote address delivered by the Governor of Central Bank of Nigeria at the Annual Executive Seminar of the Central Bank of Nigeria, holding in Abuja, the Federal Capital Territory. The theme of the Seminar was "Digitisation of Money and Monetary Policy in Nigeria.”

Special Remarks, Kingsley Obiora

Economic and Financial Review

This is the special remark delivered by the Deputy Governor, Economic Policy at the 28th edition of the CBN Executive Seminar, jointly organised by the Research and Capacity Development Departments for Executive staff of the Bank. The theme of the Seminar is, “Digitalisation of Money and Monetary Policy in Nigeria”

Digital Technology And The Transformation Of The Nigerian Banking System: The Operators’ Perspective, Ireti Samuel-Ogbu

Economic and Financial Review

The rapid development of digital technology through the years, and the rails provided by the internet for connectivity remains the most important development that has impacted change and driven massive improvement in the operation of banking and financial services. It has brought in its wake huge disruptions in product roll-out and the way products are delivered. The entry of technology companies into financial services cannot be overlooked in discussing these changes. Nigeria has not been left behind in this evolution. Instead, the Nigerian banking industry has been the forerunner in digital initiatives in Africa that have transformed the banking and …

Adoption Of The Enaira: Issues And The Way Forward, Biodun Adedipe

Economic and Financial Review

As cryptocurrencies evolved and became more popular, it became obvious that the world was trending towards monetary disintegration and oversight reversal. It was becoming fashionable for technology-motivated products to be developed either to reduce or eliminate regulation of monetary transactions. The monetary system was gradually moving towards opacity that could create a ‘safe environment’ for illegal activities and open a new vista for money laundering. This of course, should be of grave concern to any monetary authority or government.

Alumni Dedication

Washington Law Review

No abstract provided.

The Helicopter State: Misuse Of Parens Patriae Unconstitutionally Precludes Individual And Class Claims, Gabrielle J. Hanna

Washington Law Review

The doctrine of parens patriae allows state attorneys general to represent state citizens in aggregate litigation suits that are, in many ways, similar to class actions and mass-tort actions. Its origins, however, reflect a more modest scope. Parens patriae began as a doctrine allowing the British king to protect those without the ability to protect themselves, including wards and mentally disabled individuals. The rapid expansion of parens patriae standing in the United States may be partly to blame for the relative absence of limiting requirements or even well-developed case law governing parens patriae suits. On the one hand, class actions …

Obstacles To Proving 24-Hour Lighting Is Cruel And Unusual Under Eighth Amendment Jurisprudence, Lauren Jaech

Washington Law Review

Twenty-four-hour lighting causes sleep deprivation, depression, and other serious disorders for incarcerated individuals, yet courts often do not consider it to be cruel and unusual. To decide if prison conditions violate the Eighth Amendment’s prohibition against cruel and unusual punishment, courts follow a two-part inquiry that requires examining the intent of prison officials (known as the subjective prong) as well as the degree of seriousness of the alleged cruel or unusual condition (the objective prong). Incarcerated individuals often file complaints challenging 24-hour lighting conditions. Whether they succeed on these claims may depend on the circuit in which they reside. Judges …

Disorderly Content, Ari Waldman

Washington Law Review

Content moderation plays an increasingly important role in the creation and dissemination of expression, thought, and knowledge. And yet, throughout the social media ecosystem, nonnormative and LGBTQ+ sexual expression is disproportionately taken down, restricted, and banned. The current sociolegal literature, which focuses on content moderation as a whole and sees echoes of formal law in the evolution of its values and mechanics, insufficiently captures the ways in which those principles and practices are not only discriminatory, but also resemble structures of power that have long been used to police queer sexual behavior in public spaces.

This Article contributes to the …

Oral And Written Corrective Feedback In Dual Language Immersion Portuguese Classes, Janaina Quadros

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

This portfolio results from the classes, readings, writings, class observations, and reflections during my time in the MSLT program. It comprises three major components: teaching philosophy, reflections through class observations, and a reflection paper on corrective feedback. Besides that, the reader will find some background about the author’s educational and professional journey and intentions for the future.

The reflection paper focuses on oral and written corrective feedback in second language classes. It is the result of reviews of pertinent literature and the author’s experience as a Dual Language Immersion (DLI) Portuguese teacher. It gives an overview of the importance of …

Childhood And Adolescent Obesity: Related Comorbidities And Interventions, Jasmine Wong

Nursing | Senior Theses

Background

The prevalence of childhood and adolescent obesity in the United States has steadily risen over the years and has become a public health concern. Obesity is defined as a BMI at or above the 95th percentile for children and teens of the same age and sex. Obese children and adolescents are at risk for poor health and poor quality of life. Furthermore, there are numerous comorbidities associated with childhood and adolescent obesity. While some of the associated diseases are acute, others can become chronic and result in lifelong conditions.

Objective

The purpose of the present thesis is to explore …

Impact Of Intergenerational Trauma Among Immigrant And Refugee Families: Effects On The Mental Health And Acquisition Of Care, Loralee Chea

Nursing | Senior Theses

Intergenerational trauma is described as a discrete form of trauma that occurs when traumatic effects are passed across generations without the descendants of trauma survivors having exposure to the original event (Isobel et al., 2021). It is a silent suffering experienced among immigrant families from all across the world who have survived war, genocide, displacements, loss, and other psychological trauma. An exploration of literature has also shown that the healthcare crisis from this form of trauma can be identified and intervened with preventative or treatment measures in clinical practice. The purpose of this research paper is to explore the mental …

Rising Costs Of Insulin And Effects Of Self-Management In Type 1 Diabetes, Justine Yadao

Nursing | Senior Theses

Background

Type 1 diabetes, also known as juvenile diabetes or insulin-dependent diabetes is a chronic condition where the pancreas may not be able to produce little to no insulin. This type of diabetes can be attributed to some factors such as age, family history, environmental factors or types of viruses. It is seen more often in children or adolescence but can develop in adults, averaging approximately 5-10% of the population.

Insulin is a type of hormone produced in the pancreas naturally or can be manufactured in the laboratory. People with Type 1 Diabetes need insulin from an exogenous source to …

Preventing Postpartum Complications Using A Home Visitation Model Of Care, Jenna Ingram

Nursing | Senior Theses

Background

The United States is currently facing a health crisis among the maternal postpartum population. As stated by The Commonwealth Fund in a study released in 2020, “In 2018, there were 17 maternal deaths for every 100,000 live births in the U.S. – a ratio more than double of most other high-income countries” (Roosa, 2020). Most often, mothers with uncomplicated pregnancies and births are discharged soon after the delivery of their new baby. In most outpatient settings, providers do not expect a follow up appointment for the mother until roughly three to six weeks after discharge. During this transition period …

Substance Use Among Nurses As A Result Of Covid-19, And The Impact Of Rehabilitative Programs On Nurses, Gerome Macaspac

Nursing | Senior Theses

Background: The incidence of substance use among nurses has been a persistent issue for decades. The effects associated with substance misuse depend on what is used, the amount, how often, and how they are taken. Regardless of the substance used, any nurse who enters the workplace using substances puts the lives of others at risk. Due to the widespread effects of the COVID-19 pandemic, there is a risk that the number of nurses resorting to the use of substances may have increased. Therefore, an investigation into drug use among nurses during the pandemic is particularly important.

Objective: To explore the …

Compassion Fatigue: The Impact On Nurses During The Covid-19 Pandemic, Adrian Huynh

Nursing | Senior Theses

Background

Compassion fatigue comes from the physical, emotional, and psychological impact of helping others through stressful and traumatic experiences. It is a form of fatigue linked to burnout and secondary traumatic stress. Many nurses are vulnerable to compassion fatigue from repeated exposure to the trauma of their patients. While compassion fatigue has been a continuing issue, the COVID-19 pandemic has increased the risk and number of nurses developing compassion fatigue. This can affect patient care, workplace and personal relationships, and lead to development of more serious mental health issues.

Objective

To investigate the effects of compassion fatigue on the registered …

How Has The Pandemic Exacerbated Nurse Burnout, And What Can Be Done To Improve Their Psychological And Emotional Well-Being?, Lisette Diaz

Nursing | Senior Theses

Background: The COVID-19 pandemic has affected millions of people, both emotionally and physically. Nurses are among the people who are most affected. The nurses' quality of life and the way they provide care has been changed by the pandemic. Nurses are so focused on providing the best possible care for their patients that they neglect to look after themselves.

Objective: The purpose of this literature review is to identify and evaluate how the COVID-19 pandemic has affected nurses and their well-being. The significance of this research was to establish how the ongoing pandemic has impacted nurses’ performance and …

The Components Of Vaccine Hesitancy And The Role Of Patient Education In Promotion Of Vaccinations In Newborns, Camille Joy Rayo

Nursing | Senior Theses

Background

Due to an array of reasons relating to vaccine hesitancy, many newborns are without their standardized and recommended vaccinations as a result of their parent’s beliefs. Parents hold the power to vaccinate their children. Nurses must provide reliable information, debunk myths, and pursue pro-vaccination ideas when educating a parent about newborn vaccinations. By doing so, vaccine hesitancy should decrease and vaccination rates should increase. Unvaccinated newborns are put at a greater risk of contracting serious illnesses that may spread to others or even lead to one’s own death.

Objective

To identify common factors regarding vaccine-hesitant parents of the newborn …

Identifying Cultural Biases And Understanding Health Care Disparities For Lgtbq+ Patients, Jevon Nelson

Nursing | Senior Theses

Understanding the health disparities within the LGBTQ+ population, will consist of educating Nurses and other healthcare providers cultural competence for this population, along with proposing certain educational training programs for all the medical professionals. There’s not only an implicit bias but also lack in quality of healthcare due to the personal reasons that healthcare providers may have, along with certain stigmas that creates an infringement on healthcare for this specific population. Members of the LGBTQ+ community will continue to have one of the highest amounts of health care disparities due to the lack of cultural incompetence if nothing is done.

Our Early Years Of Life's Effects On Our Future Health And Well-Being, Claudia Gagliano

Nursing | Senior Theses

Many poor health outcomes later into adulthood have been triggered by adverse life events that have occurred during childhood. Most of the general population has experienced some sort of adverse childhood event that has negatively impacted their future health. Adverse childhood events include any traumatic event that has occurred during childhood including maltreatment (sexual abuse, mental abuse, and physical abuse), neglect, parental loss, and peer victimization.

Raising awareness regarding the opportunities to intervene in a child’s life as a means to prevent behavioral, psychological, and substance abuse disorders before they would typically manifest on their own is the ultimate goal. …