Digital Commons Network^™

Changes In Body Composition In Patients With Malignant Pleural Mesothelioma And The Relationship With Activity Levels And Dietary Intake, Emily Jeffery, Y. C. Gary Lee, Robert U. Newton, Philippa Lyons-Wall, Joanne Mcveigh, Deirdre B. Fitzgerald, Leon Straker, Carolyn J. Peddle-Mcintyre

Research outputs 2022 to 2026

Background:

Skeletal muscle loss is common in advanced cancer and is associated with negative outcomes. In malignant pleural mesothelioma (MPM), no study has reported body composition changes or factors associated with these changes. This study aimed to describe changes in body composition over time and its relationship with activity levels, dietary intake and survival.

Methods:

The study was a secondary analysis of data collected from a longitudinal observational study of patients with MPM. Participants completed 3-month assessments for up to 18 months. Participants with two dual-energy x-ray absorptiometry (DXA) scans were included. Changes in appendicular skeletal muscle mass (ASM) and …

Connectivity Shapes Functional Diversity And Maintains Complementarity In Surf Zones On Exposed Coasts, Christopher J. Henderson, Ben L. Gilby, Andrew D. Olds, Jesse Mosman, Rod M. Connolly, Glenn Hyndes, Brendan Kelaher, Brooke Maslo, Alan Williams, Thomas A. Schlacher

Research outputs 2022 to 2026

Habitat complexity and connectivity can influence the number of species and their diversity across a landscape. For the surf zones of ocean-exposed beaches, globally one of the longest habitat interfaces, the assumed low structural complexity, and apparent homogeneity, of the sandy seafloor habitats predicts low taxonomic and functional diversity. Here, we assessed how the configuration of the seascape and the context of different beach structure functional diversity and functional niche space of fish assemblages in surf zones. We expected that beaches that were well connected with highly productive and complex estuarine and reef habitats would support a greater level of …

Quadriceps Muscle Fatigue Reduces Extension And Flexion Power During Maximal Cycling, Steven J. O'Bryan, Janet L. Taylor, Jessica M. D'Amico, David M. Rouffet

Research outputs 2022 to 2026

Purpose:

To investigate how quadriceps muscle fatigue affects power production over the extension and flexion phases and muscle activation during maximal cycling.

Methods:

Ten participants performed 10-s maximal cycling efforts without fatigue and after 120 bilateral maximal concentric contractions of the quadriceps muscles. Extension power, flexion power and electromyographic (EMG) activity were compared between maximal cycling trials. We also investigated the associations between changes in quadriceps force during isometric maximal voluntary contractions (IMVC) and power output (flexion and extension) during maximal cycling, in addition to interindividual variability in muscle activation and pedal force profiles.

Results:

Quadriceps IMVC (−52 ± 21%, …

Determinants Of Sme’S Social Media Marketing Adoption: Competitive Industry As A Moderator, Ghazanfar Ali Abbasi, Noor Fareen Abdul Rahim, Hongyan Wu, Mohammad Iranmanesh, Benjamin Ng Chee Keong

Research outputs 2022 to 2026

In light of the growing role of social media marketing in the success of businesses and its low adoption rate among small and medium enterprises (SMEs), this study aims to identify determinants of SMEs’ social media marketing adoption by considering the competitive industry as a moderator. Data were collected from 214 SMEs in Malaysia. Unlike extant literature, this study proposed a dual-stage analysis involving partial least squares (PLS) technique and artificial intelligence named deep artificial neural network (ANN). The application of deep ANN architecture is used to predict 91% of accuracy for the proposed model. The results showed that perceived …

The Safety And Efficacy Of Using Moxibustion And Or Acupuncture For Cancer-Related Insomnia: A Systematic Review And Meta-Analysis Of Randomised Controlled Trials, Carol Chunfeng Wang, Ellen Yichun Han, Mark Jenkins, Xuepei Hong, Shuqin Pang, Lisa Whitehead, Deborah L. Kirk, Anne Williams

Research outputs 2022 to 2026

Introduction:

This study aimed to synthesise the best available evidence on the safety and efficacy of using moxibustion and/or acupuncture to manage cancer-related insomnia (CRI).

Methods:

The PRISMA framework guided the review. Nine databases were searched from its inception to July 2020, published in English or Chinese. Randomised clinical trials (RCTs) of moxibustion and or acupuncture for the treatment of CRI were selected for inclusion. Methodological quality was assessed using the method suggested by the Cochrane collaboration. The Cochrane Review Manager was used to conduct a meta-analysis.

Results:

Fourteen RCTs met the eligibility criteria. Twelve RCTs used the Pittsburgh Sleep …

Haemodiafiltration And Haemodialysis Should Be Reported Separately By Kidney Replacement Therapy Registries, Ulrich Steinwandel, Hugh Davies, Nicholas Gibson

Research outputs 2022 to 2026

No abstract provided.

An Investigation Into The Measurement Properties Of The King-Devick Eye Tracking System, M. Hecimovich, D. King, Myles Murphy, K. Koyoma

Research outputs 2022 to 2026

Objectives: Eye tracking has been gaining increasing attention as a possible assessment and monitoring tool for concussion. The King-Devick test (K-DT) was expanded to include an infrared video-oculography-based eye tracker (K-D ET). Therefore, the aim was to provide evidence on the reliability of the K-D ET system under an exercise condition. Methods: Participants (N = 61; 26 male, 35 female; age range 19-25) were allocated to an exercise or sedentary group. Both groups completed a baseline K-D ET measurement and then either two 10-min exercise or sedentary interventions with repeated K-D ET measurements between interventions. Results: The test-retest reliability of …

Geostatistical Tools To Assess Shifts In Recreational Fishing, Shannon J. Burchert, Glenn A. Hyndes, Karina Ryan, Ute Mueller

Research outputs 2022 to 2026

The use of geostatistical indices to examine fishery-dependent data over time is novel. We assess the value of a range of these indices for describing trends in boat-based recreational fishing in Western Australia and areas of high effort and catches for two demersal species with varying biological characteristics, life histories and distributions. The number of blocks (10- × 10-nautical mile (~19- × 19-km) area) visited decreased by 40%, while the number of fishing trips with demersal species catch increased by 15%. Spatial indices showed a south-easterly shift in demersal catch per unit effort (CPUE) across survey years. The southerly shift …

Matrilateral Bias Of Grandparental Investment In Grandchildren Persists Despite The Grandchildren’S Adverse Early Life Experiences, Samuli Helle, Antti O. Tanskanen, David A. Coall, Mirkka Danielsbacka

Research outputs 2022 to 2026

Evolutionary theory predicts a downward flow of investment from older to younger generations, representing individual efforts to maximize inclusive fitness. Maternal grandparents and maternal grandmothers (MGMs) in particular consistently show the highest levels of investment (e.g. time, care and resources) in their grandchildren. Grandparental investment overall may depend on social and environmental conditions that affect the development of children and modify the benefits and costs of investment. Currently, the responses of grandparents to adverse early life experiences (AELEs) in their grandchildren are assessed from a perspective of increased investment to meet increased need. Here, we formulate an alternative prediction that …

A New Comprehensive Dimensionless Inflow Performance Relationship For Gas Wells, Azim Kalantariasl, Isa Farhadi, Soosan Farzani, Alireza Keshavarz

Research outputs 2022 to 2026

Prediction of gas well deliverability is important for reservoir management. Conventional flow after flow, isochronal or modified isochronal tests are common methods for calculation of well deliverability. Single-point test using Vogel-type dimensionless inflow performance relationships (IPR) was also proposed to overcome the need for multi-point tests. However, analysis of field data showed that existing dimensionless IPR correlations fail to accurately predict well deliverability for some reservoir conditions. In this study, a wide range of reservoir rock and fluid data was used to develop a comprehensive dimensionless IPR correlation for calculation of gas well deliverability from single-point test data. Multi-point well …

Application Of Benchtop Humidity And Temperature Chamber In The Measurement Of Water Vapor Sorption In Us Shales From Mancos, Marcellus, Eagle Ford And Wolfcamp Formations, Hesham Abdulelah, Berihun Mamo Negash, Atta Dennis Yaw, Tareq M. Al-Shami, Ahmed Al-Yaseri, Eswaran Padmanabhan

Research outputs 2022 to 2026

A benchtop humidity and temperature chamber was used to assess water vapor sorption in four US shale samples at 90 °C. Water sorption isotherms were measured at relative humidity ranging from 10 to 99% and temperature of 90 °C. Shale fractal properties were then evaluated, and capillary pressure (ranging from 1.70 to 386 MPa) was obtained using Kelvin relationship. The results show that Mancos shale, from the US, adsorbed more absorbed water due to its high clay concentration and low TOC. However, Wolfcamp shale, from the US, has the lowest TOC and clay concentration, adsorbing the lowest amount of water. …

Barriers And Facilitators To Exercise Among Adult Cancer Survivors In Singapore, Alexandre Chan, Kayleen Ports, Patricia Neo, Mothi Babu Ramalingam, Ang Tee Lim, Benedict Tan, Nicolas H. Hart, Raymond J. Chan, Kiley Loh

Research outputs 2022 to 2026

Purpose:

Exercise can help cancer survivors manage sequela, treatment side effects, improve overall quality of life, and is recommended for most. The purpose of this study was to investigate exercise behavior and factors influencing exercise engagement among cancer survivors at the National Cancer Centre, Singapore (NCCS).

Methods:

This cross-sectional study was inclusive of survivors of all cancer types and stages who were at least 21 years of age and had undergone chemotherapy at the NCCS. Surveys were utilized to assess survivor barriers and facilitators to exercise and to retrospectively assess physical activity and exercise behaviors at 4 cancer-related time periods …

Elastic Tubes: The Ideal Equipment For Telehealth Exercise Medicine In The Management Of Prostate Cancer?, Georgios Mavropalias

Research outputs 2022 to 2026

Prostate cancer (PCa) affects 1 in 8 men, but exercise therapy has been shown to be a very effective intervention not only to induce physiological benefits but to also reduce the side effects of cancer treatments typically administered during PCa. The COVID19 pandemic has restricted access to exercise clinics, a problem which always existed for people living in rural and remote areas. This caused many exercise physiologists and researchers to transition their clinic-based exercise to online, home-based exercise. We would like to propose that researchers and exercise physiologists should consider the use of elastic tubes in both research and the …

Exercise In Advanced Prostate Cancer Elevates Myokine Levels And Suppresses In-Vitro Cell Growth, Jin Soo Kim, Dennis R. Taaffe, Daniel A. Galvão, Nicolas H. Hart, Elin Gray, Charles J. Ryan, Stacey A. Kenfield, Fred Saad, Robert U. Newton

Research outputs 2022 to 2026

Background:

Altering the systemic milieu through exercise has been proposed as a potential mechanism underlying exercise-driven tumour suppression. It is not yet known whether men with advanced prostate cancer can elicit such adaptations following a program of exercise. The purpose is to examine myokine levels of serum acquired from metastatic castrate-resistant prostate cancer (mCRPC) patients recruited to the INTERVAL-GAP4 trial before and after 6 months of exercise and its tumour-suppressive effect.

Methods:

Twenty-five men with mCRPC (age = 74.7 ± 7.1 yrs) were randomised to supervised multimodal (aerobic and resistance) exercise (EX) or self-directed exercise control group (CON). Body composition …

Modeling Digital Camera Monitoring Count Data With Intermittent Zeros For Short-Term Prediction, Eben Afrifa-Yamoah, Ute Mueller

Research outputs 2022 to 2026

Digital camera monitoring has revolutionised survey designs in many fields, as an important source of information. The extended sampling coverage offered by this monitoring scheme makes it preferable compared to other traditional methods of survey. However, data obtained from digital camera monitoring are often highly variable, and characterized by sparse periods of zero counts, interspersed with missing observations due to outages. In practice, missing data of relatively shorter duration are mostly observed and are often imputed using interpolation techniques, ignoring long-term trends leading to inherent estimation biases. In this study, we investigated time series forecasting methods that adequately handle intermittency …

Navigating Loss And Value Trade-Offs In A Changing Climate, Karen Paiva Henrique, Petra Tschakert, Chantal Bourgault Du Coudray, Pierre Horwitz, Kai Daniel Christian Krueger, Alexander James Wheeler

Research outputs 2022 to 2026

Climate change puts at risk what people value in their everyday lives, with evidence of harm and suffering already taking place across all regions of the world. As societies slowly come to grips with the possibility of not being able to save everything that is valued, there is an urgent need to identify what is most important for individuals and groups, to prioritise action and prevent or minimise intolerable losses. Yet, people's priorities vary greatly; individual choices are contingent on what people hold dear in the places they inhabit, which in turn is shaped by their positioning in society and …

Threat Assessment, Sense Making, And Critical Decision-Making In Police, Military, Ambulance, And Fire Services, Greg Penney, David Launder, Joe Cuthbertson, Matthew B. Thompson

Research outputs 2022 to 2026

Military and emergency response remain inherently dangerous occupations that require the ability to accurately assess threats and make critical decisions under significant time pressures. The cognitive processes associated with these abilities are complex and have been the subject of several significant, albeit service specific studies. Here, we present an attempt at finding the commonalities in threat assessment, sense making, and critical decision-making for emergency response across police, military, ambulance, and fire services. Relevant research is identified and critically appraised through a systematic literature review of English-language studies published from January 2000 through July 2020 on threat assessment and critical decision-making …

Walking Improvement In Chronic Incomplete Spinal Cord Injury With Exoskeleton Robotic Training (Wise): A Randomized Controlled Trial, Dylan J. Edwards, Gail Forrest, Mar Cortes, Margaret M. Weightman, Cristina Sadowsky, Shuo-Hsiu Chang, Kimberly Furman, Amy Bialek, Sara Prokup, John Carlow, Leslie Vanhiel, Laura Kemp, Darrell Musick, Marc Campo, Arun Jayaraman

Research outputs 2022 to 2026

Study design:

Clinical trial.

Objective:

To demonstrate that a 12-week exoskeleton-based robotic gait training regimen can lead to a clinically meaningful improvement in independent gait speed, in community-dwelling participants with chronic incomplete spinal cord injury (iSCI).

Setting:

Outpatient rehabilitation or research institute.

Methods:

Multi-site (United States), randomized, controlled trial, comparing exoskeleton gait training (12 weeks, 36 sessions) with standard gait training or no gait training (2:2:1 randomization) in chronic iSCI ( > 1 year post injury, AIS-C, and D), with residual stepping ability. The primary outcome measure was change in robot-independent gait speed (10-meter walk test, 10MWT) post 12-week intervention. Secondary …

Wanji-Wanji: The Past And Future Of An Aboriginal Travelling Song, Myfany Turpin, Calista Yeoh, Clint Bracknell

Research outputs 2022 to 2026

Classical Aboriginal culture in Australia consists of many different kinds of ceremonies, including travelling ceremonies that are often shared across linguistic and geographical boundaries. Each of these ceremonies is made up of dozens of different verses. Perhaps the most widely known travelling ceremony is one referred to in some areas as ‘Wanji-wanji’. This was known over half the country and dates back at least 170 years, as evidenced in eleven legacy recordings and fieldwork interviewing more than 100 people across the western half of Australia. Like any oral tradition, the names of such ceremonies vary from place to place and …

Women's Experiences Of Breech Birth Decision Making: An Integrated Review, Sara E. Morris, Deborah Sundin, Sadie Geraghty

Research outputs 2022 to 2026

INTRODUCTION: Currently, caesarean section is the primary mode of birth for a breech presenting fetus, leading to a deskilling of clinicians and limitation of birth choices for women. The aim of this review is to present a synthesized summary of existing literature related to women's experiences of breech birth mode decision-making. METHODS: A systematic search of the literature was conducted in April 2021, utilizing five databases to identify and obtain peer-reviewed articles meeting the predetermined selection criteria. RESULTS: Four major categories were synthesized from the integrated review: 1) Women who desire a vaginal birth may experience a range of negative …

Bystander Behaviour In Australian Nightlife Settings: Appendix A - Interview Guide, Aimee-Rose Wrightson-Hester, Alfred Allan, Maria Allan

Research outputs 2022 to 2026

A semi-structured interview guide that was used to conduct interviews exploring young Australian nightlife users' perceptions of factors that might influence bystander behaviour in Australian nightlife settings. The interview guide includes a vignette depicting an incident of sexual violence that commonly occurs in nightlife settings.

A Translational Research Framework For Nurse Practitioners, Mary Ryder, Elisabeth Jacob

Research outputs 2022 to 2026

Aims This study aims to explore a proposed translational research continuum for nurse practitioners. Background Nurse practitioners are acknowledged as clinical leaders responsible for transforming health care delivery. It is important that nurse practitioners contribute to health care knowledge using scientific processes for the implementation of evidence-based practice and evaluation of outcomes of interventions for their patient groups. Evaluation This paper provides a review of translational research literature including implementation science to align nurse practitioner activities to a modified translational research framework. Key Issues A translational research framework has the potential to strengthen nursing research in the nurse practitioner role. …

Do Liquid Assets Lure Managers? Evidence From Corporate Misconduct, Rashid Zaman, Nader Atawnah, Muhammad Nadeem, Stephen Bahadar, Irfan H. Shakri

Research outputs 2022 to 2026

We examine the effect of asset redeployability on corporate misconduct and find a significant positive relationship. Utilizing a large sample of public US firms for the period of 2001 to 2015, we find that a one standard deviation (SD) increase in the proportion of redeployable assets leads to a 7.2% increase in corporate fines. We also find that the positive association between asset redeployability and corporate misconduct varies across types of misconduct and industrial heterogeneity. In our channel analysis, we find that managerial risk-taking is a potential mechanism through which asset redeployability is associated with misconduct. Additional tests reveal that …

Positive Family Relationships In A Digital Age: Hearing The Voice Of Young People, Nicola F. Johnson, Zoe Francis

Research outputs 2022 to 2026

This study focused on young people's perspectives about family relationships and how they can be strengthened or weakened through digital media practices. Located in Melbourne, Australia, 20 participants aged between 13 and 17 years were interviewed about how digital devices and practices shaped the way they interacted with family. The thematic analysis points to the young people's commitment to family cohesion. This was demonstrated through responsible use of social media, admitting the need for device-free time, acknowledging the challenges of being online, and their sense of responsibility as a family member, which informed and shaped the way they individually acted.

Overview Of Aboriginal And Torres Strait Islander Health Status, 2021, Australian Indigenous Healthinfonet

Research outputs 2022 to 2026

The main purpose of the Overview of Aboriginal and Torres Strait Islander health status (Overview) is to provide a comprehensive summary of the most recent indicators of the health and current health status of Australia’s Aboriginal and Torres Strait Islander people. The Overview has been prepared by HealthInfoNet staff as part of our contribution to supporting those who work in the Aboriginal and Torres Strait Islander health sector. The Overview is a key indicator of the HealthInfoNet’s commitment to authentic and engaged knowledge development and exchange. The initial sections of this Overview provide information about the context of Aboriginal and …

Summary Of Aboriginal And Torres Strait Islander Health Status - Selected Topics 2021, Australian Indigenous Healthinfonet

Research outputs 2022 to 2026

...The HealthInfoNet has prepared this Summary as part of our contribution to support those who work in the Aboriginal and Torres Strait Islander health sector. Key health topics are summarised in plain language and an infographic style to enable readers to absorb data easily and quickly...

Associations Of Specific Types Of Fruit And Vegetables With Perceived Stress In Adults: The Ausdiab Study, Simone Radavelli-Bagatini, Marc Sim, Lauren C. Blekkenhorst, Nicola P. Bondonno, Catherine P. Bondonno, Richard Woodman, Joanne M. Dickson, Dianna J. Magliano, Jonathan E. Shaw, Robin M. Daly, Jonathan M. Hodgson, Joshua R. Lewis

Research outputs 2022 to 2026

Purpose:

Higher total fruit and vegetable (FV) intakes have been associated with lower perceived stress. The relationship between specific types of FV and perceived stress remains uncertain. The aims of this cross-sectional study were to explore the relationship between consumption of specific types of FV with perceived stress in a population-based cohort of men and women aged ≥ 25 years from the Australian Diabetes, Obesity and Lifestyle (AusDiab) Study.

Methods:

Dietary intake was assessed using a validated Food Frequency Questionnaire (n = 8,640). Perceived stress was evaluated using a validated Perceived Stress Questionnaire, with values ranging 0–1 (lowest to highest). …

Dual Contribution Of The Gut Microbiome To Immunotherapy Efficacy And Toxicity: Supportive Care Implications And Recommendations, Hannah R. Wardill, Raymond J. Chan, Alexandre Chan, Dorothy Keefe, Samuel P. Costello, Nicolas H. Hart

Research outputs 2022 to 2026

The efficacy of immune checkpoint inhibitors (immunotherapy) is increasingly recognized to be linked to the composition the gut microbiome. Given the high rates of resistance, interventions targeting the gut microbiome are now being investigated for its ability to improve the efficacy of immunotherapy. In light of recently published data demonstrating a strong correlation between the efficacy and toxicity of immunotherapy, there is a risk that efforts to enhance immunotherapy efficacy may be undermined by increases in immune-related adverse events (IrAEs) This is particularly important for microbial interventions aimed at increasing immunotherapy efficacy, with many microbes implicated in tumour response also …

Future Perspectives Of Uveal Melanoma Blood Based Biomarkers, Aaron B. Beasley, Fred K. Chen, Timothy W. Isaacs, Elin S. Gray

Research outputs 2022 to 2026

Uveal melanoma (UM) is the most common primary intraocular malignancy affecting adults. Despite successful local treatment of the primary tumour, metastatic disease develops in up to 50% of patients. Metastatic UM carries a particularly poor prognosis, with no effective therapeutic option available to date. Genetic studies of UM have demonstrated that cytogenetic features, including gene expression, somatic copy number alterations and specific gene mutations can allow more accurate assessment of metastatic risk. Pre-emptive therapies to avert metastasis are being tested in clinical trials in patients with high-risk UM. However, current prognostic methods require an intraocular tumour biopsy, which is a …

Thermoeconomic Analysis And Multi-Objective Optimization Of A Novel Trigeneration System Consisting Of Kalina And Humidificationdehumidification Desalination Cycles, Pooria Behnam, Meysam Faegh, Iman Fakhari, Pouria Ahmadi, Ehsan Faegh, Marc A. Rosen

Research outputs 2022 to 2026

Low-temperature geothermal heat sources have the highest share of geothermal energy in the world. Utilization of these heat sources for energy and freshwater generation can play an important role in meeting energy and freshwater demands. To do so, this study aims to propose a novel trigeneration cycle powered by low-temperature geothermal sources. The proposed system, which is an integration of Kalina and humidification-dehumidification (HDH) cycles, is used for the generation of electricity, heating, and freshwater. For the Kalina cycle, an evaporative condenser is used. It also acts as a humidifier and heater of the humidification-dehumidification desalination cycle, resulting in a …