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2022

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Distorted Reality: A Commentary On Dimarco Et Al. (2022) And The Question Of Male Sexual Victimization, B. Kennath Widanaralalage, Shon M. Reed, Maria João Lobo Antunes, Christina Dejong, Gillian M. Pinchevsky, Rachel Lovell, Cristy E. Cummings Jan 2022

Distorted Reality: A Commentary On Dimarco Et Al. (2022) And The Question Of Male Sexual Victimization, B. Kennath Widanaralalage, Shon M. Reed, Maria João Lobo Antunes, Christina Dejong, Gillian M. Pinchevsky, Rachel Lovell, Cristy E. Cummings

Sociology & Criminal Justice Faculty Publications

Our commentary responds to claims made by DiMarco and colleagues in an article published in this journal that the majority of victims of rape are men and that 80% of those who rape men are women. Although we strongly believe that studying male sexual victimization is a highly important research and policy endeavour, we have concerns with the approach taken by DiMarco and colleagues to discuss these incidents. Specifically, we critique their paper by addressing the definitions of rape used by the authors, questioning their interpretation of national victim surveys, evaluating their analysis of the underreporting of male rape, and …


Civiic: Cybercrime In Virginia: Impacts On Industry And Citizens Final Report, Randy Gainey, Tancy Vandecar-Burdin, Jay Albanese, Thomas Dearden, James Hawdon, Katalin Parti Jan 2022

Civiic: Cybercrime In Virginia: Impacts On Industry And Citizens Final Report, Randy Gainey, Tancy Vandecar-Burdin, Jay Albanese, Thomas Dearden, James Hawdon, Katalin Parti

Sociology & Criminal Justice Faculty Publications

[First paragraph] Victimization from cybercrime is a major concern in Virginia, the US, and the world. As individuals and businesses spend more time online, it becomes increasingly important to understand cybercrime and how to protect against it. Such an understanding is dependent on valid and reliable baseline data that identifies the specific nature, extent, and outcomes of cybercrime activity. A better understanding of cybercrime activity is needed to target and prevent it more effectively, minimize its consequences, and provide support for both individual and corporate victims. Before that can occur, however, better baseline data are required, and this project was …


Feasibility And Applicability Of Evenson Sedentary Behavior Cut Points Applied To Children With And Wihtout Intellectual And Developmental Disabilities, Bethany Forseth, Paula E. Papanek, Michele Polfuss Jan 2022

Feasibility And Applicability Of Evenson Sedentary Behavior Cut Points Applied To Children With And Wihtout Intellectual And Developmental Disabilities, Bethany Forseth, Paula E. Papanek, Michele Polfuss

Exercise Science Faculty Research and Publications

Aim

Sedentary behavior (SB) is widely studied as it is associated with cardiometabolic health and obesity issues. However, children with Intellectual and Developmental Disabilities (IDD) have been understudied. Accelerometers are commonly used to measure SB in typically developing populations but may be inappropriate for IDD populations due to differences in body movement and physiologic responses to the activity. The use of Evenson sedentary cut-points, created based on typically developing children, has yet to be applied and/or examined in children with IDD.

Purpose

A descriptive cross-sectional study was conducted to (1) Assess the feasibility of applying Evenson sedentary cut-points in children …


Maximal Strength In Relation To Force And Velocity Patterns During Countermovement Jumps, Michael H. Haischer, John Krzyszkowski, Stuart Roche, Kristof Kipp Jan 2022

Maximal Strength In Relation To Force And Velocity Patterns During Countermovement Jumps, Michael H. Haischer, John Krzyszkowski, Stuart Roche, Kristof Kipp

Exercise Science Faculty Research and Publications

Maximal strength is important for the performance of dynamic athletic activities, such as countermovement jumps (CMJ). Although measures of maximal strength appear related to discrete CMJ variables, such as peak ground reaction forces (GRF) and center-of-mass (COM) velocity, knowledge about the association between strength and the time series patterns during CMJ will help characterize changes that can be expected in dynamic movement with changes in maximal strength. Purpose: To investigate the associations between maximal strength and GRF and COM velocity patterns during CMJ. Methods: Nineteen female college lacrosse players performed 3 maximal-effort CMJs and isometric midthigh pull. GRF …


Resilience Among Older Adults With Multiple Sclerosis: Pattern And Correlates, Dena Sadeghi-Bahmani, Ariel Kidwell, Rachel E. Bollaert, Robert W. Motl Jan 2022

Resilience Among Older Adults With Multiple Sclerosis: Pattern And Correlates, Dena Sadeghi-Bahmani, Ariel Kidwell, Rachel E. Bollaert, Robert W. Motl

Exercise Science Faculty Research and Publications

Background

There is an increasing number of older adults with multiple sclerosis (MS) who present with significant challenges associated with aging in conjunction with a chronic, disabling disease. Resilience has been associated with healthy aging in the general population, yet there is limited research on resilience and its correlates among older adults with MS. The current study investigated the difference in resilience between older adults with MS and demographically matched healthy controls. We then examined the associations between resilience and functional, symptomatic, socio-behavioral, and QOL outcomes, along with demographic and clinical characteristics, among only older adults with MS. Method: The …


Hip And Knee Joint Angle Patterns And Kicking Velocity In Female And Male Professional Soccer Players: A Principal Component Analysis Of Waveforms Approach, Archit Navandar, Kristof Kipp, Enrique Navarro Jan 2022

Hip And Knee Joint Angle Patterns And Kicking Velocity In Female And Male Professional Soccer Players: A Principal Component Analysis Of Waveforms Approach, Archit Navandar, Kristof Kipp, Enrique Navarro

Exercise Science Faculty Research and Publications

This study used principal component analysis (PCA) of waveforms to extract movement patterns from hip and knee angle time-series data; and determined if the extracted movement patterns were predictors of ball velocity during a soccer kick. Twenty-three female and nineteen male professional soccer players performed maximal effort instep kicks while motion capture and post-impact ball velocities data were recorded. Three-dimensional hip and knee joint angle time-series data were calculated from the beginning of the kicking leg’s backswing phase until the end of the follow-through phase and entered into separate PCAs for females and males. Three principal components (PC) (i.e., movement …


And Still, I Rise: Madre Poderosas In The Pursuit Of Work-Life Justice In Educational Leadership Roles, Janet Oseguera-Valencia Jan 2022

And Still, I Rise: Madre Poderosas In The Pursuit Of Work-Life Justice In Educational Leadership Roles, Janet Oseguera-Valencia

Dissertations

The purpose of this mixed-methods study was to: (1) to describe and understand Latina leaders' experiences, perceptions, and challenges work-family conflict cause from an institutional, cultural, and individual lens; (2) and understand Latina leaders experiences, perceptions and helpful solutions work-life justice may create from an institutional, cultural, and individual lens. This study used quantitative data from a survey, and qualitative data from interviews. There were a total of sixty-three Latina leaders that participated in the survey and eighteen interviewed. The conceptual framework for this study centered around (1) a history of work-family conflict in educational leadership; (2) the complexities of …


Communal Storywork: Deaf Education And The Latine Community, Noralee Jasso Jan 2022

Communal Storywork: Deaf Education And The Latine Community, Noralee Jasso

Dissertations

In order to challenge the dominant and deficit perspectives in deaf education, this study utilized a Critical Race Theory framework to examine Latine families with Deaf children as they are portrayed in literature across areas of policy, research, and practice. Through qualitative semi-structured interviews, this research project invited nine adult Latine family members with Deaf children to share their lived experiences with having a Deaf child as part of the family and within a California school. To center the experiences of Latine families with Deaf children as visible, legitimate and necessary constituents of their children’s educational journeys, this research required …


An Unconventional Pathway: A Qualitative Inquiry Into The Experience Of Racial Minority Transfer Students, Hanh My Mai Tran Jan 2022

An Unconventional Pathway: A Qualitative Inquiry Into The Experience Of Racial Minority Transfer Students, Hanh My Mai Tran

Dissertations

Transfer students’ success is increasingly being discussed in higher education. A large population of transfer students includes racial minority, low-income, and first-generation college students. Due to the multiple layers of students’ identities, it has been difficult for educational leaders in institutions to grasp the essential elements needed to serve these students. As a result, this qualitative study contributes to this discussion and efforts to support the transfer student’s success. In this study, qualitative methods, including interviews with 14 students from 4-year universities and community colleges and a survey, were used to identify the steps and resources associated with supporting transfer …


Culturally Responsive School Leadership In Continuation High Schools: An Alternative Approach In Leadership Styles, Roberto C. Portillo Jan 2022

Culturally Responsive School Leadership In Continuation High Schools: An Alternative Approach In Leadership Styles, Roberto C. Portillo

Dissertations

Continuation high schools and the students they serve are often invisible and ignored to most Californians. However, state school authorities estimate that over 115,000 California high school students will pass through one of the state's 519 continuation high schools each year, to either graduate with a diploma, or to drop out of school altogether (Austin & Dixon, 2008). Principals in these schools must be exceptional and well prepared. However, principals have been trained to implement culturally responsive school leadership at their sites. Eight continuation high school principals described their experiences regarding their preparation, supports, challenges and successes in implementing culturally …


Emerging Policy And Practice Issues (2021), Steven L. Schooner, David Berteau Jan 2022

Emerging Policy And Practice Issues (2021), Steven L. Schooner, David Berteau

GW Law Faculty Publications & Other Works

This paper/chapter, presented at the Thomson Reuters Government Contracts Year in Review Conference (covering 2021), attempts to identify some the leading, evolving trends and issues in U.S. federal procurement. Consistent with prior practice, this chapter offers extensive coverage of the federal procurement (and grant) and defense spending trends and attempts to predict what lies ahead, particularly with regard to legislative and executive activity. This year's paper discusses, among other things, the flurry of activity in the public procurement sphere as the Biden administration accelerates efforts to restore and reshape the government, special emergency procurement authorities deployed during the coronavirus pandemic, …


Breached! Why Data Security Law Fails And How To Improve It (Chapter 1), Daniel J. Solove, Woodrow Hartzog Jan 2022

Breached! Why Data Security Law Fails And How To Improve It (Chapter 1), Daniel J. Solove, Woodrow Hartzog

GW Law Faculty Publications & Other Works

Digital connections permeate our lives—and so do data breaches. Given that we must be online for basic communication, finance, healthcare, and more, it is remarkable how difficult it is to secure our personal information. Despite the passage of many data security laws, data breaches are increasing at a record pace. In their book, BREACHED! WHY DATA SECURITY LAW FAILS AND HOW TO IMPROVE IT (Oxford University Press 2022), Professors Daniel Solove and Woodrow Hartzog argue that the law fails because, ironically, it focuses too much on the breach itself.

Drawing insights from many fascinating stories about data breaches, Solove and …


Artificial Intelligence Accountability Of Public Administration, Francesca Bignami Jan 2022

Artificial Intelligence Accountability Of Public Administration, Francesca Bignami

GW Law Faculty Publications & Other Works

This article canvasses the use and regulation of artificial intelligence (AI) in US administrative agencies. It is structured as a reply to the questionnaire circulated in advance of the 2022 International Congress of Comparative Law for purposes of preparing the national reports and the general report on the topic of “Artificial Intelligence Accountability of Public Administration.” In large part, the questionnaire’s point of reference is the comprehensive regulation of AI in the European Union’s proposed AI Act. The US reply, contained in this article, highlights the many lacunae in US regulation of AI, similar to the US’s patchwork approach to …


Peremptory Norms Of General International Law (Jus Cogens) (Revisited) And Other Topics: The Seventy-Third Session Of The International Law Commission, Sean D. Murphy Jan 2022

Peremptory Norms Of General International Law (Jus Cogens) (Revisited) And Other Topics: The Seventy-Third Session Of The International Law Commission, Sean D. Murphy

GW Law Faculty Publications & Other Works

The International Law Commission (ILC) held its seventy-third session from April 18 to June 3 and from July 4 to August 5, 2022 in Geneva, under the chairmanship of Dire Tladi (South Africa). This session was the final one of the quinquennium, which originally would have occurred in the summer of 2021 but for the COVID-19 pandemic.

During the seventy-third session, the Commission completed the second reading of two topics: peremptory norms of general international law (jus cogens); and protection of the environment in relation to armed conflicts. The Commission completed a first reading of the topic on immunity of …


The Uncitral Model Law On Public Procurement: Potential Next Steps, Christopher R. Yukins, Caroline Nicholas Jan 2022

The Uncitral Model Law On Public Procurement: Potential Next Steps, Christopher R. Yukins, Caroline Nicholas

GW Law Faculty Publications & Other Works

The current version of the Model Law on Public Procurement was approved by the United Nations Commission on International Trade Law (UNCITRAL) in 2011, after a drafting process which spanned nearly a decade. This version of the Model Law reflects best practices which were emerging in procurement systems across the world during the first decade of this century. There have been calls for an update of the Model Law, and this draft chapter, after reviewing the history of the Model Law and the reforms which led to the current version, discusses various reforms which might be made to the text …


Eliminating The Fugitive Disentitlement Doctrine In Immigration Matters, Tania N. Valdez Jan 2022

Eliminating The Fugitive Disentitlement Doctrine In Immigration Matters, Tania N. Valdez

GW Law Faculty Publications & Other Works

Federal courts of appeals have declared that they may dismiss immigration appeals filed by noncitizens who are deemed “fugitives.” The fugitive disentitlement doctrine emerged in the criminal context with respect to defendants who had escaped from physical custody. Although the doctrine originated out of concerns that court orders could not be enforced against criminal fugitives, the doctrine has since crept into civil contexts, including immigration. But rather than invoking the doctrine for its originally intended purpose of ensuring that court orders could be enforced, courts now primarily invoke it for the purposes of punishment, deterrence, and protecting the dignity of …


Exploring Corporate Stakeholders’ Perspectives On Building Capacity For Employee Engagement In Workplace Wellness Initiatives, Abiola O. Keller, Rebecca Berman, Barb Scotty, Daniel Pinto Jan 2022

Exploring Corporate Stakeholders’ Perspectives On Building Capacity For Employee Engagement In Workplace Wellness Initiatives, Abiola O. Keller, Rebecca Berman, Barb Scotty, Daniel Pinto

Physician Assistant Studies Faculty Research and Publications

Engaging employees with chronic conditions as partners in designing, implementing, and evaluating workplace wellness activities is a promising approach for optimizing the impact of workplace health promotion programs. Yet, there is a need for information on how employees are engaged in this process. We conducted a process evaluation of activities of the Patient-Centered Outcomes Research for Employees (PCORE) project formed around building capacity for employee engagement in wellness initiatives. Individual interviews were conducted with the 11 project stakeholders to explore perspectives of the project's participatory process and activities. Thematic categories emerging in the analysis were (1) Commitment and support, (2) …


Privacy Concerns With Using Public Data For Suicide Risk Prediction Algorithms: A Public Opinion Survey Of Contextual Appropriateness, Michael Zimmer, Sarah Logan Jan 2022

Privacy Concerns With Using Public Data For Suicide Risk Prediction Algorithms: A Public Opinion Survey Of Contextual Appropriateness, Michael Zimmer, Sarah Logan

Computer Science Faculty Research and Publications

Purpose

Existing algorithms for predicting suicide risk rely solely on data from electronic health records, but such models could be improved through the incorporation of publicly available socioeconomic data – such as financial, legal, life event and sociodemographic data. The purpose of this study is to understand the complex ethical and privacy implications of incorporating sociodemographic data within the health context. This paper presents results from a survey exploring what the general public’s knowledge and concerns are about such publicly available data and the appropriateness of using it in suicide risk prediction algorithms.

Design/methodology/approach

A survey was developed to measure …


An Mhealth App-Based Self-Management Intervention For Family Members Of Pediatric Transplant Recipients (Myfami): Framework Design And Development Study, Riddhiman Adib, Dipranjan Das, Sheikh Iqbal Ahamed, Stacee M. Lerret Jan 2022

An Mhealth App-Based Self-Management Intervention For Family Members Of Pediatric Transplant Recipients (Myfami): Framework Design And Development Study, Riddhiman Adib, Dipranjan Das, Sheikh Iqbal Ahamed, Stacee M. Lerret

Computer Science Faculty Research and Publications

Background

Solid-organ transplantation is the treatment of choice for children with end-stage organ failure. Ongoing recovery and medical management at home after transplant are important for recovery and transition to daily life. Smartphones are widely used and hold the potential for aiding in the establishment of mobile health (mHealth) protocols. Health care providers, nurses, and computer scientists collaboratively designed and developed mHealth family self-management intervention (myFAMI), a smartphone-based intervention app to promote a family self-management intervention for pediatric transplant patients’ families.

Objective

This paper presents outcomes of the design stages and development actions of the myFAMI app framework, along with …


Accelerating Spatial Autocorrelation Computation With Parallelization, Vectorization And Memory Access Optimization, Anmol Paudel, Satish Puri Jan 2022

Accelerating Spatial Autocorrelation Computation With Parallelization, Vectorization And Memory Access Optimization, Anmol Paudel, Satish Puri

Computer Science Faculty Research and Publications

No abstract provided.


Digital Tradition (2022), Loreto Pérez Ferre Jan 2022

Digital Tradition (2022), Loreto Pérez Ferre

Grado en Diseño de Moda

La pandemia ha causado un cambio en la industria textil. Por un lado las empresas han reducido su impacto durante los meses de confinamiento ante la bajada de ventas, mientras que han tenido que emplear plataformas digitales y distintos métodos para seguir llevando al cabo su producción. Ante todos estos cambios surgió un nuevo sector al que se le ha identificado como la moda digital. En este proyecto hemos investigado sobre los beneficios que tiene este sector tanto a nivel de eficacia como en la reducción de impacto medioambiental, a la vez que como herramienta para generar contenido. Para ello …


Understory Structure And Heterospecifics Influence The Occupancy Of A Ground-Nesting Species Of Conservation Concern, The Canada Warbler, Gordon W. Dimming, Christopher Rota, Petra Wood, Christopher M. Lituma Jan 2022

Understory Structure And Heterospecifics Influence The Occupancy Of A Ground-Nesting Species Of Conservation Concern, The Canada Warbler, Gordon W. Dimming, Christopher Rota, Petra Wood, Christopher M. Lituma

Faculty & Staff Scholarship

Forest structure and composition in eastern U.S. forests are changing because of forest regeneration after farmland abandonment, less frequent occurrence of severe disturbances, and climate change. Some of these changes may disproportionally affect birds that rely on gap dynamics or other forest canopy disturbances to create understory habitat. The Canada Warbler (Cardellina canadensis) is one such understory specialist that has undergone consistent declines. We assessed environmental and interspecific factors associated with Canada Warbler space use in its southern breeding distribution to understand potential causes of population declines and inform conservation efforts. We evaluated Canada Warbler occupancy from 840 …


Random Misalignment And Anisotropic Deformation Of The Nested Cladding Elements In Hollow-Core Anti-Resonant Fibers, Michael Petry, Rodrigo Amezcua-Correa, Md Selim Habib Jan 2022

Random Misalignment And Anisotropic Deformation Of The Nested Cladding Elements In Hollow-Core Anti-Resonant Fibers, Michael Petry, Rodrigo Amezcua-Correa, Md Selim Habib

Electrical Engineering and Computer Science Faculty Publications

Hollow-core anti-resonant fibers (HC-ARFs) are en route to compete with and surpass the transmission performance of standard single-mode fibers (SSMFs). Recently, nested cladding elements emerged as a key enabler in reaching ultra-low transmission losses over a wide bandwidth. However, implementing nested geometry features poses a great challenge even in the current state-of-the-art fiber fabrication technology, often leading to structural imperfections, which ultimately worsen overall fiber performance. This article provides insights into the impact of fabrication-based perturbations of the cladding elements on the transmission performance and identifies areas of highest susceptibility. The impact of random outer and nested cladding tube misalignments …


Evaluating The Influence Of Twitter Bots Via Agent-Based Social Simulation, Aldo Averza, Khaled Slhoub, Siddhartha Bhattacharyya Jan 2022

Evaluating The Influence Of Twitter Bots Via Agent-Based Social Simulation, Aldo Averza, Khaled Slhoub, Siddhartha Bhattacharyya

Electrical Engineering and Computer Science Faculty Publications

Social Media is used by many as a source of information for current world events, followed by publicly sharing their sentiment about these events. However, when the shared information is not trustworthy and receives a large number of interactions, it alters the public's perception of authentic and false information, particularly when the origin of these stories comes from malicious sources. Over the past decade, there has been an influx of users on the Twitter social network, many of them automated bot accounts with the objective of participating in misinformation campaigns that heavily influence user susceptibility to fake information. This can …


Enhancing Cybersecurity By Generating User-Specific Security Policy Through The Formal Modeling Of User Behavior, Arwa Alqadheeb, Siddhartha Bhattacharyya, Samuel Perl Jan 2022

Enhancing Cybersecurity By Generating User-Specific Security Policy Through The Formal Modeling Of User Behavior, Arwa Alqadheeb, Siddhartha Bhattacharyya, Samuel Perl

Electrical Engineering and Computer Science Faculty Publications

Organizations today are faced with the difficult challenge of balancing the embrace of new and emerging technology, and securing their systems and data that support critical business functions. Although there have been significant advances in security enforcement technology, attackers are still able to compromise organizations and access. The impacts of computer intrusions have become so untenable that many organizations are looking at a drastic rethinking of their approach to the security of internal networks. This approach is called Zero Trust and it seeks to remove all notion of a trusted internal network boundary. The benefits of Zero Trust include significantly …


A Machine Learning Approach To Predicting Sep Events Using Properties Of Coronal Mass Ejections, Jesse Torres, Lulu Zhao, Philip K. Chan Jan 2022

A Machine Learning Approach To Predicting Sep Events Using Properties Of Coronal Mass Ejections, Jesse Torres, Lulu Zhao, Philip K. Chan

Electrical Engineering and Computer Science Faculty Publications

Solar energetic particles (SEPs) can cause severe damage to astronauts and their equipment, and can disrupt communications on Earth. A lack of thorough understanding the eruption processes of solar activities and the subsequent acceleration and transport processes of energetic particles makes it difficult to forecast the occurrence of an SEP event and its intensity using conventional modeling with physics-based parameters. Therefore, in order to provide an advance warning for astronauts to seek shelter in a timely manner, we apply neural networks to forecast the occurrence of SEP events. We use the properties of coronal mass ejections (CMEs) archived in the …


Automatic Verification Of Multi-Agent Systems Security Properties Specified With Ltl, Kholud Alghamdi, Marius Silaghi Jan 2022

Automatic Verification Of Multi-Agent Systems Security Properties Specified With Ltl, Kholud Alghamdi, Marius Silaghi

Electrical Engineering and Computer Science Faculty Publications

We propose a way to verify security requirements of critical multi-agent system processes by using logic representations and automatic reasoning. The typical multi-agent system considered in our work would be an election system with agents representing their users and aiming to ensure security. Relevant processes are authentication, voting, re-voting, and election verification. The security requirements commonly addressed in such a voting system are: no user can vote unless it got authenticated, no invalid vote should be counted, no vote should be counted twice, and each valid vote should be eventually counted. We show a model of such security requirements by …


Reproductive Regrets Among A Population-Based Sample Of U.S. Women, Arthur L. Greil, Michele H. Lowry, Andrea R. Burch, Kathleen Slauson-Blevins, Nicholas Park, Julia Mcquillan Jan 2022

Reproductive Regrets Among A Population-Based Sample Of U.S. Women, Arthur L. Greil, Michele H. Lowry, Andrea R. Burch, Kathleen Slauson-Blevins, Nicholas Park, Julia Mcquillan

Sociology & Criminal Justice Faculty Publications

Women have many reproductive options, but little is known about their regrets regarding prior reproductive choices and outcomes. Guided by the life-course and stratified reproduction perspectives, this study draws on an open-ended question about reproductive regrets from wave I of the National Survey of Fertility Barriers, a representative telephone survey of reproductive aged U.S. women conducted from 2004 to 2006. The authors classified regrets into five broad categories: (1) none, (2) problematic fertility, (3) unfulfilled fertility desires, (4) family, and (5) pregnancy experiences. The authors conducted the analyses separately by motherhood status. Logistic regression analysis revealed that regardless of parental …


Covid-19 Vaccination In Palestine/Israel: Citizenship, Capitalism, And The Logic Of Elimination, Nicolas Howard, Emily Schneider Jan 2022

Covid-19 Vaccination In Palestine/Israel: Citizenship, Capitalism, And The Logic Of Elimination, Nicolas Howard, Emily Schneider

Sociology & Criminal Justice Faculty Publications

Despite Israel’s responsibility under international law to combat the spread of contagious diseases and epidemics in its occupied territories, Israeli officials have refused to distribute COVID-19 vaccines to Palestinians in the West Bank and Gaza Strip. Through a critical discourse analysis of Israeli officials’ statements regarding Israel’s COVID-19 vaccination campaign, this paper explores how Israel evades this responsibility while presenting itself as committed to public health and human rights. We find that Israeli officials strategically present Palestinians as an autonomous nation when discussing COVID-19 vaccinations, despite Israel’s ongoing attempts to prevent the creation of a Palestinian state. Relatedly, Israel justifies …


Induction Immunotherapy Followed By Thoracic Radiation Without Chemotherapy In Unresectable Stage Iii Non-Small Cell Lung Cancer: A Case Series., Srikiran Dasari, Takefumi Komiya Md Jan 2022

Induction Immunotherapy Followed By Thoracic Radiation Without Chemotherapy In Unresectable Stage Iii Non-Small Cell Lung Cancer: A Case Series., Srikiran Dasari, Takefumi Komiya Md

PCI Publications and Projects

OBJECTIVE: Although concurrent chemoradiation has been the standard of care for unresectable stage III non-small cell lung cancer (NSCLC) due to increased survival and decreased disease progression, patients with poor performance status cannot tolerate chemotherapy toxicity well. Durvalumab, an immune checkpoint inhibitor targeting the programmed death receptor-1 (PD-1) / programmed death-ligand 1 (PD-L1) axis, demonstrated efficacy as maintenance therapy after definitive chemoradiation. However, the role of immunotherapy in those who cannot tolerate chemoradiation is unclear.

METHODS: This retrospective case series reports adult patients with PD-L1-expressing stage III NSCLC diagnosed at Parkview Cancer Institute from 2019-2021 and treated initially with pembrolizumab …