Digital Commons Network^™

Processes Underlying Black American College Students’ Mental Health: Examining The Roles Of Mental Health Literacy, Ethnic-Racial Identity, And Mental Health-Related Behaviors, Chloe Walker

Theses and Dissertations

Addressing the mental health of college students is a persistent and increasing priority (Auerbach et al., 2018), especially among Black American individuals. Given prevalent mental health disparities, it is critical to understand the association between Black American emerging adults’ mental health literacy (MHL) and mental health outcomes including promotive mental health-related behaviors (MHRBs) and symptoms (i.e., anxiety and depressive symptoms), and the modifiable underlying factors that inform them. Guided by the Theory of Planned Behavior (Ajzen, 1991) and the Identity-based Motivation theory (Oyserman & Yoder, 2007), the present study aimed to examine the relation between mental health literacy and mental …

Progress Towards Next Generation Modulators Of Ctbp's Oncogenic Effects, Jacqueline L. West

Theses and Dissertations

Human C-terminal binding proteins (CtBP1 and CtBP2) are transcriptional coregulators of multiple genes in the human genome, including tumor suppressor genes (e.g., Bik, PTEN, BRCA1, and E-cadherin) as well as oncogenes (e.g. MDR1 and Tiam1). Both homologues of CtBP are overexpressed in many types of cancer, including breast cancer (92%), ovarian cancer (83%), colorectal cancer (64%), hepatocellular carcinoma (60%), gastric cancer, prostate cancer, and pancreatic adenocarcinoma. Further, expression levels of CtBP correlate with worse prognostic outcomes and more aggressive tumor features because it promotes proliferation, epithelial-mesenchymal transition, and cancer stem cell self-renewal activity.

Our laboratory has identified a lead inhibitor …

The L1-Norm Regularized L1-Norm Best-Fit Line Problem And Applications, Xiao Ling

Theses and Dissertations

The best-fit subspace or low-rank approximation of a data matrix revolves
around the norm approximation technique. l²-norm criterion is probably the most
widely used norm for fitting subspaces. As the computational power increases, the
l¹-norm analogue has recently gained attention from the academic community. It is
widely agreed that the l¹ norm is insensitive to outliers, compared to its l² variant.
Because of the polyhedral structure interrelated with linear programming (LP),
the l⁰ norm is commonly relaxed into the l¹-norm problem to induce sparsity in
models. In this work, we examine …

Puddlefist, Dylan Ahern

Theses and Dissertations

This written thesis focuses on my MFA thesis exhibition, Puddlefist. It begins with an introduction to both the artworks and my artistic approach, then discusses the text Transcendental Black Metal by Hunter Hunt-Hendrix, which serves as a larger reference point for the work. The latter part of this written thesis is a narrative influenced by the convergence of the sculptures that comprise the exhibition. I consider it a form of endurance writing that exercises motifs of noise, mantra, and monotony. In the section entitled Puc and Yellow, NPC (non-playable character) dialogue from the video game Fallout: New Vegas is transcribed …

Viral Overexpression Of Rprd2 In Mouse Nucleus Accumbens Induces Anxiety-Like Behavior And Regulates Genes Associated With Microtubule Transport, Claire Nuhad Atiyeh

Theses and Dissertations

Anxiety disorders are the most prevalent mental illness in the United States with many individuals underdiagnosed and undertreated (Anxiety & Depression Association of America, 2021; Bandelow et al., 2017). While stress is a known risk factor for developing anxiety disorders, there is emerging evidence that biological variability in the expression of key proteins in the brain may contribute to regulating an organism’s stress-related behaviors. Earlier work from our laboratory identified a protein, called Regulation of Nuclear Pre-mRNA Domain Containing 2 (RPRD2), that was differentially expressed in the brain of mice stratified in terms of their phenotypic response to chronic stress …

Varied Levels Of Fructose Consumption Induce Physiological, Cognitive, And Mitochondrial Alterations In Aged Female Rats, Emilie L. Bjerring

Theses and Dissertations

Since the 1970s, fructose consumption has dramatically increased within the United States, as well as the world. While adolescents tend to be the largest consumer of fructose, mostly seen in the form of sugary beverages, the consequences of a high fructose diet started in adulthood can also have severe implications on physiological parameters as well as cognition. Several studies have linked fructose consumption to metabolic syndrome, a clustering of symptoms related to overall health, with particular emphasis placed on obesity, type II diabetes, and the relationship with Alzheimer’s Disease. These findings largely stem from the outcomes of studies on cognition, …

Parental Attitudes Regarding The Primary Dentition, Dental Decay, And Trauma, Kathryn Dundervill

Theses and Dissertations

Purpose: The purpose of this study is to identify the ability of parents in the VCU Pediatric Dental Clinic to recognize signs of decay and trauma and to determine their knowledge regarding the primary dentition.

Methods: This is a cross-sectional study that determined parental attitude and knowledge toward the function of primary teeth, childhood dental decay and dental trauma. Study data was collected through REDCap, a secure web-based survey application. Parents who brought their child to the VCU Pediatric Dental Clinic for a new patient examination or a recall examination were included in the study. The survey was only formatted …

Automated Conjecturing On The Independence Number And Minimum Degree Of Diameter-2-Critical Graphs, Joshua R. Forkin

Theses and Dissertations

A diameter-2-critical (D2C) graph is a graph with diameter two such that removing any edge increases the diameter or disconnects the graph. In this paper, we look at other lesser-studied properties of D2C graphs, focusing mainly on their independence number and minimum degree. We show that there exist D2C graphs with minimum degree strictly larger than their independence number, and that this gap can be arbitrarily large. We also exhibit D2C graphs with maximum number of common neighbors strictly greater than their independence number, and that this gap can be arbitrarily large. Furthermore, we exhibit a D2C graph whose number …

Challenges Among Latine Daca Recipients And Anxiety: A Systematic Meta-Analytic Review, Isis A. Garcia-Rodriguez

Theses and Dissertations

Immigrant-origin Latine young adults (ILYAs) face a challenge that is specific to their developmental period. As ILYAs transition from high school to beyond (e.g., workforce, college, etc.), they begin to grapple with participating in normative experiences for all young adults in the U.S. (e.g., obtaining a driver’s license, getting their first job at 16). The lives of ILYA, particularly those who are DACAmented or DACA eligible, are characterized by the legal and social contradiction that arises from growing up in the U.S. yet facing barriers to full participation in U.S. society. The nonexistent synthesis of the exponentially growing literature in …

Exploring Dynamic Navigation For Palatally Impacted Canine Uncovery Surgery., Daniel Joseph Hall

Theses and Dissertations

Purpose: The objective of this study was to compare the exposure/uncovery of palatally impacted canines via the use of dynamic navigation guidance to the traditional freehand approach. Outcomes evaluated include the time to plan and perform exposure, area/size of initial access to locate the impacted tooth and the final size of the osteotomy to completely uncover the impacted tooth.

Methods: In order to simulate various frequently encountered clinical scenarios, three different model types were used. Six plastic models of each model type were fabricated from epoxy resin. Each model contained 2 bilaterally, palatally impacted canines, that were randomly embedded in …

Madeleine Béjart: La Femme Galante, Katherine E. Jackson

Theses and Dissertations

The 17th Century marked the beginning of women professionally joining the acting profession and as such brought about change in the career opportunities for women. Madeleine Béjart was one of these actresses who is notorious for her liaison and working relationship with famed playwright, Molière. Through this personal relationship her role in history was relegated to that of mistress and the scandal concerning Molière’s wife Armande who is speculated to either be Madeleine's daughter or sister. By using historical and biographical information on Madeleine along with two works of Molière in which she originated roles, I will explore the intricacies …

Threshold Levels Of Patient And Parent Esthetic Concern In The Mixed Dentition, Justin Josell

Theses and Dissertations

Purpose: The mixed dentition is a period of unique dental changes for developing children and their parents. The purpose of this study is to determine threshold levels of concern regarding diastema spacing and angulation of maxillary incisors during the “Ugly Duckling Stage” in pediatric patients and their parents.

Methods: This study is modeled as a cross sectional-survey among pediatric patients and parents. The surveys contain photographs of a sex-neutral, mixed-dentition smile with variations of midline spacing and incisal angulation which randomly differ in quantifiable values. Participants were asked to rate each photograph on a visual analog scale.

Results: The interaction …

How Is Biophilic Urbanism Being Used In Planning To Rejuvenate Post-Industrial Cities?, Andrea A. Kerley

Theses and Dissertations

ARE POST-INDUSTRIAL CITIES USING BIOPHILIC URBANISM TO MERGE NATURE AND THE BUILT ENVIRONMENT? A PLAN EVALUATION OF FOUR U.S. LEGACY CITIES

By Andrea (Andi) Ames Kerley, Master in Urban and Regional Planning

A thesis submitted in partial fulfillment of the requirements for the degree of Master of Urban and Regional Planning, at Virginia Commonwealth University.

Virginia Commonwealth University, 2020.

Major Director: Megan Z. Gough, Associate Professor, L. Douglas Wilder School of Government and Public Affairs,

Urban and Regional Studies and Planning

The re-imaging of U.S. post-industrial cities from desolate, impoverished, and polluted areas to unique, equitable, and environmentally aware cities …

Taking Flight: An Independent Living Facility For Emancipated Foster Youth, Kristy Mcdaniel Leitzel

Theses and Dissertations

Motivation

Many of us think about foster care in the context of younger children removed from home. However, little thought is given to youth that age out of the foster care system and the associated challenges and risks they face, namely in the area of housing.

Youth in foster care often receive minimal support in making the transition to independence and are frequently forced into instant adulthood. They are faced with an abrupt end of support at a time when they have not yet mastered the educational, social, or economic survival skills necessary to be independent in the community (Haas, …

Until Its Calmness Can Claim You, Gabrielle Mchugh

Theses and Dissertations

This is an invitation to pause //

This is an externalization of my inner landscape, a highlight of what I value in my everyday and what comprises my lexicon of a sacred space. The following is a journey of nets, quiet, the sacred, space, and the in-between; where I share research and questions that are the foundation for my thesis work, Until Its calmness can claim you.

// This is an invitation to find moments of quiet in the noise

Dregs / Lessons From The Things Around Us, Juan-Manuel Pinzon

Theses and Dissertations

The writing in Lessons From the Things Around Us is in support of the work in my MFA thesis show, dregs. I detail the progression of my making and thinking over the last two years. I expand on the material and personal relationships that have manifested themselves in the work and influenced my approach to the things that surround me. Finally, I point to a more expansive definition of Craft, rooted in its material sensibilities, and the possibilities already present in the field that this definition creates.

Holler: An Exploration Of Appalachian Performativity, David Powell

Theses and Dissertations

Holler: An Appatragedy is a play written in order to indict, examine and contemplate the toxic ideals of Appalachian culture. The play and the following in-depth character analysis are meant to portray a quartet of siblings who have been abandoned by their parents due to undisclosed issues (potentially addiction or mental health issues) and left to be cared for by their grandparents.

Throughout the events of the play, the culture is questioned as the elder siblings return from their lives outside Appalachia to attend the grandmother’s funeral, colliding with their brother and scheming to help their youngest brother escape from …

Relief Revival Reincarnation, Lisa Moon

Theses and Dissertations

there is a complex connectivity that we have with the built environment that goes beyond visual aesthetics and stimulates each of our senses. this connectivity is tied to our identity and the way we contextualize our experiences and our world. inspired by ethnographic observations, oscar newman’s seminal work, + the pruitt-igoe documentary, the project seeks to study the elements of this connectivity or in some cases the reduced connectivity within a public housing residential environment.

what contributes to this reduced connectivity?

newman examined it from an architectural perspective, exterior elements of building, space designation, corridors, skip|stop elevators, circulation patterns, natural …

Again Black Again, Muthi Reed

Theses and Dissertations

ABSTRACT

AGAIN BLACK AGAIN

by muthi reed, M.F.A

A thesis submitted in partial fulfillment of the requirements for the degree of Master of Fine Arts at Virginia Commonwealth University.

Program Director: Stephen Vitiello

Committee: Semi Ryu, Orla McHardy, MK Abadoo, Cara Benedetto

AGAIN BLACK AGAIN. ABA-BBABB is documentation of a reparations practice and articulations for a reparations manifesto devised by the artist. Reparations begins with the self. Singing truth to the self. Talking with the self. The thesis organizes around the problems of surveillance and myth making about Black people and the subsequent source of self-regard, conjure and social dreaming …

Misled Youth, Mark Tan

Theses and Dissertations

I’m a first-generation Canadian who was born and raised in Toronto, Ontario by Asian immigrants. I have migrated to the United States and lived here for 7 years. Through my work, I express the emotional value of preconceived notions, disconnectedness, and longing in search of finding place and acceptance within a community. Drawing from memory, personal narrative, emotion, and perception, I manipulate data into lines, forms, and materials through a subjective human experience from the lens of a non-citizen. By projecting the migration movement of my family lineage from China and the Philippines to Canada as well as my path …

Periodic Trends In The Infrared And Optical Absorption Spectra Of Metal Chalcogenide Clusters, Alain Ward

Theses and Dissertations

We have investigated the Optical absorption, Infrared spectra, Binding Energies, and various other cluster properties to determine the existence of periodic trend for Transition Metal Chalcogenide Clusters ligated with CO ligands. We were motivated to answer the question of whether periodic behavior can be observed in properties of octahedral metal-chalcogenide clusters. We have used the Amsterdam Density Functional code to calculate the electronic structure of Transition Metal Chalcogenide Clusters using gradient-corrected density functional theory. We determined the existence of several periodic trends in properties of octahedral Transition Metal Chalcogenide Clusters TM₆Se₈(CO)₆. To investigate these …

Connections Exposed | A Library For The People, Stephanie Wilburn

Theses and Dissertations

MOTIVATION

The U.S. economy, democracy, and the health and happiness of citizens depends on maintaining social capital, the networks of bonds between community members. Social capital creates the trust that facilitates action and cooperation for mutual benefit. Since the 1960s, there has been a decline in-person socialization and social bonds both within and between demographic groups in the US resulting in reduced social capital (Putnam, 2000).

One measure to combat declining social capital is to create third places where incidental and repeated social interactions build and reinforce bonds between community members (Oldenburg, 1997).

With the reduction of accessible and inclusive …

An Exploration Of A Researcher-Instructor Partnership In Implicit Racial Bias Awareness And Mitigation In College Stem Classrooms, Jacqueline Johnson Wilson

Theses and Dissertations

Seventy-six percent of all minority students who enter college with declared majors in science, technology, engineering, and mathematics (STEM) do not graduate with STEM degrees. Black students represent 40% of minority attrition from STEM. Implicit racial bias was indicated as a contributor to the challenges faced by Black students. The purpose of this study was to explore whether a researcher-instructor partnership brought awareness to and the potential for mitigation of implicit racial bias in course delivery and instructor interactions with Black students in STEM classes. A case study design was used over three phases to gather survey, observational, and interview …

Towards New Antimalarial Drug: Depolarization Of Liposomal Membranes By Aminooxoethylcarbamothioate In The Presence Of Fe3+ Ions, Aaron Wilson

Theses and Dissertations

Despite the efforts of scientists around the world 409,000 people died of malaria in 2019 alone. According to the WHO 90% of those deaths occurred in Africa. Despite the high number of available treatments, malaria continues to plague many parts of the world. This is due in part to drug resistance developed among mosquito populations as well as limited access to medicines that do work. Furthermore, when traveling to malaria prone areas, pretreatment with a chemoprophylaxis is common practice. However, often the side effects to malaria pretreatment are severe. A new approach to the treatment of malaria is a compound …

Sociodemographic And Injury Severity Characteristics As Predictors Of Functional Independence In Older Adults With Tbi Up To 10 Years Post Injury, Carmen M. Tyler

Theses and Dissertations

Traumatic brain injury (TBI) incidence rates have been increasing in recent years, with the greatest number of TBIs and the highest morbidity and mortality rates in individuals aged 80 and over. As average life expectancy continues to increase, the older adult population is expected to comprise nearly one-quarter of the U.S. populace by 2060. With the increased risk to a larger proportion of the U.S. population posed by TBI, the aim of the current study was to examine the roles of sociodemographic and injury severity characteristics as predictors of functional independence trajectories across 1, 2, 5, and 10 years after …

Sound Of Systems Music Therapy For Autism, Nishtha Chawla

Theses and Dissertations

ABSTRACT

Sound of Systems- Impact of Music Therapy on Adolescents with Autism

“Music – The child of number and sound”.” --Iannis Xenakis

Motivation.

Music, a language that crosses cultures and can compel an individual to transcend time and space. It is an expression of the highest order and a gateway to connect to our divine source, it precedes all biases. Music therapy has been utilized in the Islamic world since the 8th century for its healing and therapeutic effects on the human soul, spirit, and body.

As of 2020, 1 in every 54 children is diagnosed with Autistic Spectrum Disorder …

Considering Queerness - Actor Training's Issues And Alternatives, Jacob Leblanc

Theses and Dissertations

Educators in academic theatre programs, whether queer or non-queer, trans or cisgender, may not intentionally consider queerness in their pedagogical practices. What follows is an examination of current issues in academia that can affect queer students negatively and disproportionately. Anecdotal evidence is provided to demonstrate different issues that may be present in the classroom experiences of queer students. The Stanislavski system is critiqued through a contemporary, queer lens to locate possible shortcomings in the acting technique when it is applied by queer performers. Queer alternatives to the Stanislavski system are vetted and offered to queer students who might seek something …

The Economic Value Of Pharmacist-Physician Collaborative Care Models In Hypertension Management, Jessica S. Jay

Theses and Dissertations

Background: Hypertension is highly prevalent in the United States, affecting nearly half of all adults (43%). Studies have shown that pharmacy-physician collaborative care models (PPCCM) for hypertension management significantly improve blood pressure (BP) control rates and provide consistent control of BP. Time in target range (TTR) for systolic BP is a novel measure of BP control consistency that is independently associated with decreased cardiovascular (CV) risk. There is no evidence observed improvement in TTR for systolic BP with PPCCM is cost effective.

Objective: This study aimed to compare the cost-effectiveness of PPCCM with usual care for the management of hypertension …

Shackled: To A Front-Row Seat Of My Own Horror Film, Dellil L. Mohammed

Theses and Dissertations

This document serves as internal view point, stemming from my experiences as a black muslim, first generation Ethiopian American, overall identity, and it’s disorienting implication on my interpretation of my view-self and the world. This is also informed by my struggling with the realities of type-1 diabetes and the sporadic and often inadequate support of the American health system. All of these intersecting experiences have led to me making work as an agent for advocacy, empathy and social justice. This work is also informed and dressed with the elements of horror, sci-fi, & fantasy. See and hear the voice in …

Characterizing Senescence Induction And Senolytic Sensitivity In Murine Lung Cancer Cell Lines, Rana A. Estaleen

Theses and Dissertations

While cancer patients often experience tumor reduction after receiving chemotherapy, tumors can eventually emerge from a state of dormancy. Cancer cells treated with the topoisomerase II poison, etoposide (ETO), enter senescence, which is a durable and prolonged cell cycle growth arrest. Different murine lung cell lines were screened for their levels of senescence induction by ETO, and those showed promising senescence induction were then treated with the senolytic, ABT263, to promote apoptosis. The hypothesis of this work was that non-small cell lung cancer cell lines will have different degrees of senescence and that the magnitude of the response to senolytics …