Characterizing The Effects Of Solvent And Analyte Properties On Ionization Efficiency By Novel Field-Free And Field-Enabled Ionization Techniques, Kinkini Udara Jayasundara

Graduate Theses, Dissertations, and Problem Reports (ETD)

In recent years the mass spectrometry (MS) area of field and/or direct analysis has grown dramatically. As a result, field-portable and miniaturized mass spectrometers, introduced only a few years ago, are proliferating. A highly desired feature for field-portable MS, or in-field analysis, is the ability to use ionization techniques requiring very little sample preparation as well as an ability to generate the ions under ambient conditions. Recently, a new ambient ionization technique termed vibrating sharp-edge spray ionization (VSSI) has been introduced which overcomes the field-portable limitations of other spray-based methods including the requirements for auxiliary components (e.g., nebulizing gas and …

Evaluating Remote Economic Benefits Of Watershed-Scale Acid Mine Drainage Restoration, Rachel E. Pell

Graduate Theses, Dissertations, and Problem Reports (ETD)

In 2011, the West Virginia Abandoned Mine Lands and Reclamation Program (WVAML) implemented a watershed-scale restoration project in Three Fork Creek, a 103 square-mile watershed in rural West Virginia impaired by acid mine drainage (AMD). This was accomplished through the installation of four in-stream lime dosers in 2011. Due to the great capital investment in the restoration of Three Fork Creek and an interest in applying this watershed-scale approach to other watersheds throughout West Virginia, it is of great interest to demonstrate the successes of this remediation. It has already been demonstrated that the watershed has visibly improved and is …

Implementation Of Stress Management And Resiliency Training To Address Nursing Burnout In A Neuroscience Critical Care Unit, Jessica May Marie Hughes

Graduate Theses, Dissertations, and Problem Reports (ETD)

In the United States, over one-third of nurses experience symptoms of burnout (Reith, 2018). If left unchecked, poor stress management and resiliency skills can contribute to nursing burnout, leading to costly employee turnover. Stress management and resiliency training (SMART) provides the tools necessary to develop resiliency, improve stress management and decrease burnout (Resilient Option, 2020). Nursing staff under the age of 36, who work in a Neurosciences Critical Care Unit (NCCU) demonstrate lower resiliency scores and a higher risk of burnout. This project aimed to evaluate: (a) the effects of a SMART program on the wellbeing of nursing staff in …

Standardized Postoperative Handoff Tool To Improve Handoff Quality, Haley Durkacz

Graduate Theses, Dissertations, and Problem Reports (ETD)

Abstract

Effective communication between healthcare providers is an essential element in the delivery of safe patient care. Loss of relevant information can occur during all phases of patient care but is most inclined to occur during the handoff from the operating room to the postoperative anesthesia care unit (PACU). Evidence has indicated that the transfer of patients by anesthesia providers remains informal and brief despite practice guidelines. When pertinent details are omitted during the anesthesia handoff there is a potential increase for medical errors, delayed treatment, and patient harm. The purpose of this project was to analyze the use of …

A Quality Improvement Initiative Regarding Ondansetron In The Prevention Of Spinal Anesthesia-Induced Hypotension, Kassidy Dell Nutter

Graduate Theses, Dissertations, and Problem Reports (ETD)

Spinal anesthesia is an excellent choice as the primary anesthetic for lower abdominal, perineal, and lower extremity procedures. Spinal anesthesia boasts several distinct advantages over general anesthesia. However, it is important to note that spinal anesthesia does not come without risk. The most common adverse reaction of spinal anesthesia is hypotension. Anesthesia providers use several methods to combat the hypotension that is so commonly associated with spinal anesthesia. One emerging trend to prevent spinal anesthesia-induced hypotension (SAIH) is the administration of ondansetron, a serotonin 5-hydroxytryptamine3 antagonist. Evidence has shown that the administration of ondansetron just prior to spinal anesthesia administration …

Influences Of Seawater Flows On The Degradation Of Organic Coatings Applied On Offshore Wind Turbines, Amin Vedadi

Mechanical Engineering and Applied Mechanics

The regular protection methods of offshore wind structures consist of the application of two or three layers of epoxy-based coatings with a polyurethane topcoat. The coating systems of offshore wind turbines are mostly tested on-site, where different coated samples are exposed to the sea water at the specific locations planned for the installations of the turbines. Despite several advantages of laboratory testing, the majority of laboratory-based tests have been limited to the exposure of coated or unprotected metals to stationary electrolytic solutions, while the flow-induced corrosion measurements have not received enough attention until recently. The focus of our work is …

Implementation Of An Amiodarone Infusion Nurse Practice Guideline To Reduce The Incidence Of Phlebitis: A Quality Improvement Project, Kristen N. Cottrill

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background: Patients have an increased risk of developing phlebitis when amiodarone is delivered through a peripheral intravenous catheter. In a 32-bed cardiac surgery step-down unit, patients experienced phlebitis at a rate of 28.57% despite following manufacturer recommendations. Individual interventions targeted at amiodarone-related phlebitis have presented mixed results, however, when an amiodarone infusion practice guideline was established, the rate and severity of phlebitis consistently decreased across studies. Purpose: This project aimed to implement an evidence-based amiodarone infusion guideline to reduce phlebitis development or severity in cardiac-surgery step-down patients without a central venous catheter who received a peripheral intravenous infusion of amiodarone. …

A Quality Improvement Initiative For Intraoperative Low Dose Ketamine Utilization In Thoracotomy, Jason Wampler

Graduate Theses, Dissertations, and Problem Reports (ETD)

The challenge of postoperative pain control following a thoracotomy is well noted among anesthesia providers. The intraoperative utilization of low-dose ketamine in several patient populations, including those undergoing a thoracotomy, has been deemed a viable intervention in the multi-modal analgesia plan at not only reducing postoperative pain scores for patients, but also reducing opioid consumption. This quality improvement project sought to increase provider awareness of this intervention among anesthesia providers in a community hospital with a goal to influence a practice change. This was completed using a pre-post design centered around an educational in-service, with an additional 60-day follow-up survey …

An Anesthesia-Based Quality Improvement Initiative To Decrease Opioid Administration Via Esmolol Administration, Fredrick J. Hanna

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background: Laryngoscopy and endotracheal intubation are routine procedures that occur within the surgical setting. Fentanyl is currently administered for attenuating the hemodynamic response to intubation. Opioid-sparing alternatives have been identified with aims of improving patient outcomes, such as esmolol. Purpose: The project’s purpose was designed to improve anesthesia provider familiarity, perception, and consideration of esmolol as a non-narcotic alternative for attenuating the hemodynamic response to intubation and prompt an increase of esmolol administration within this setting. Interventions: Surveys were conducted before and after an educational in-service, offered to anesthesia providers, demonstrating esmolol as an efficacious alternative to fentanyl. Additionally, an …

Process Optimization Of 3d Printing With Continuous Fiber Reinforced Uv Curable Thermoset Resin, Md Atikur Rahman

Mechanical Engineering and Applied Mechanics

3D printed polymer components cannot be used as structural components due to the 3D printable material property limitations. To improve mechanical properties, a composite 3D printer is developed and studied. Technical aspects of 3D printing with continuous carbon fiber reinforced dual UV and thermal curable thermoset composite were experimented. To optimize the 3D printing process parameters, the effect of printing nozzle size, line spacing of the print, and resin flow rate was studied. To achieve minimum void content and maximum fiber volume fraction, print parameter configurations were studied using microscopic surface roughness analysis. The tensile and flexural properties of 3D …

A Review Of Biomechanics Of Arterial Stent Implants, Joshua Collin Yurek

Mechanical Engineering and Applied Mechanics

This work looks to provide a review of modern stents by evaluating the need for them as well as providing a detailed engineering analysis of the conditions they are subjected to. It is estimated that over two million of these devices are implanted in patients annually. Of those implanted, a majority are used in the treatment of arteriosclerosis. This disease causes arterial walls to thicken and toughen leading to restricted blood flow and in extreme cases, complete loss of circulation. Arteriosclerosis and complications arising from it form a leading cause of death in the developed world. Although there are a …

An Experimental Study Of Fluid-Structure Interaction In Collapsible Vessels, Jennifer Schmeling

Mechanical Engineering and Applied Mechanics

The fluid-structure interaction in collapsible thin-walled vessels is an important topic of research to better understand the physical mechanisms behind many physiological processes and diseases. In this work, we established an experimental setup to study the collapsible tube deformation and fluid-structure interaction within a thin-walled collapsible vessel. The effects of transmural pressure and flow rate were characterized experimentally using high-frequency pressure transducers and optical measurements. Various transmural pressures were also simulated through finite element analysis. Results suggest that the deformation of thin-wall vessel follows the pattern described by Shapiro’s tube law. The collapsed pattern and cross-sectional area changes with different …

Characterization Of A Lab-Scale Polymethylmethacrylate And Gaseous Oxygen Hybrid Rocket, Porter Dixon

Mechanical Engineering and Applied Mechanics

Hybrid rockets are a type of chemical rocket propulsion where the reactants are in different phases. Historically, hybrid rockets have been underutilized in the aerospace industry. However, due to their simple nature, they are easy to construct and test. Research on hybrid rocket propulsion was conducted using optically clear polymethylmethacrylate and gaseous oxygen with a nozzle designed to achieve Mach 2. Characterization was performed using combustion simulations available from NASA and measurements with pressure transducers, thermocouples, a load cell, and high-speed cameras. The test stand and hybrid rocket itself were designed by previous senior design groups. From the results, performance …

Working Knowledge: Catalogers And The Stories They Tell, Amanda Belantara, Emily Drabinski

Publications and Research

Cataloging librarians make myriad choices every day as they create the metadata necessary for information retrieval. Each record represents an interaction between the cataloger and the systems they work within and, sometimes, against. Their work is highly constrained by standardized machine-readable fields and codes, controlled subject terms, and classification schema. In the exploratory research project Catalogers at Work, the authors use sound recording to reveal the complex yet hidden negotiations embedded in library catalog records.

Llegir, Escriure, Escoltar: Els Paisatges Sonors De Guillem Frontera, Antoni Pizà

Publications and Research

Resumen:

El ensayo presenta una panorámica de las novelas y ensayos de Guillem Frontera (Ariany, Mallorca, 1945) y examina el papel de la música en su producción literaria. En sus primeras obras de los años sesenta y setenta hay una gran cantidad de referencias al jazz, el rock y el pop. Esos géneros son vistos como un signo de modernidad y cosmopolitismo normalmente traído por el turismo de masas a Mallorca. Los escritos posteriores incluyen muchas referencias a la música clásica, especialmente la música sacra, y presentan la música como un refugio espiritual, una protección contra del ruido de la …

La Musique Dans Les Cultures Tech. La Synthèse Modulaire En Temps De Covid-19, Eliot Bates

Publications and Research

Depuis 1996, la synthèse modulaire matérielle est passée d’une pratique artisanale de fabrication d’instruments de niche soutenue par un petit nombre de musiciens, à un phénomène transnational, une véritable culture tech. Malgré cet engouement, elle n’a pas donné naissance à de nouveaux genres musicaux populaires, et il n’est pas certain que la « musique », quelle que soit sa définition, soit ce qui rassemble les amateurs de synthèse modulaire. Ce texte a deux objectifs : tout d’abord, il présente les résultats d’une recherche en cours menée en ligne et dans plusieurs pays concernant le rôle des objets technologiques dans la …

“It Wasn’T Just About Learning How To Speak Spanish”: Engaging Histories Of Oppression And Enslavement In Spanish Heritage Language Education, Tania Avilés, Anthony J. Harb

Publications and Research

We present a curricular intervention in elementary Spanish heritage language in a Hispanic serving institution located in the US Northeast (Bronx, NYC), that aims to contextualize Latinx students’ experiences and perceptions of Blackness within broader histories of oppression and enslavement. Our practice brings together critical Latinx pedagogy and critical approaches to Spanish heritage language education to facilitate sociohistorical consciousness for both language instructors and students through the use of open-access Latinx archival resources. We outline a three-week unit designed using the First Blacks in the Americas online collection curated by the City University of New York Dominican Studies Institute. During …

Getting Back: The Chiffons’ Sonic Reclamation, Hilarie Ashton

Publications and Research

Sixties girl group the Chiffons are famous for their soaring 1964 hit “He’s So Fine,” a song in turn remembered almost as often for its plagiarism by George Harrison than in its own right. Much of the rest of their catalogue, including the tremendous “I Have a Boyfriend,” gets shunted into historical and critical gaps that paint rock music history as controlled by men. In this article, I examine the Chiffons in their own right, reframing a story of well-worn sonic theft to center on the group it obscured, through and alongside interpretative contradictions, assumptions, and historical lacunae. I show …

Network Slicing In 5g: Admission, Scheduling, And Security, Raneem Jassim Alghawi

Graduate Theses, Dissertations, and Problem Reports (ETD)

In the past few decades, there was an increase in the number of devices that have wireless capabilities such as phones, televisions, and home appliances. With the high demand for wireless networking, the fifth generation (5G) of mobile networks was designed to support the different services of new applications. In addition, one of the technical issues that 5G would evolve is the increase in traffic and the need to satisfy the user’s experience. With the evolution of wireless networking and 5G, Network Slicing has been introduced to accommodate the diverse requirements of the applications. Thus, network slicing is the concept …

Adverse Childhood Experiences And Alcohol Use Trajectories In College Students, Rebekah Lynn Damitz

Graduate Theses, Dissertations, and Problem Reports (ETD)

Heavy alcohol use during college can result in numerous negative outcomes (e.g., accidents, worse academics, risky sexual behaviors, etc.). Understanding the risk-factors associated with elevated alcohol use in college are needed so prevention and/or interventions can be implemented to inhibit such dangerous behavior. Adverse childhood experiences have been identified as one key factor in the initiation and escalation of alcohol use, but there is limited research on samples that are in emerging adulthood. Specifically, the transition to college is a time when many students escalate drinking and can form the basis for longer term drinking patterns. It is not yet …

Syntheses Of Indoles And Natural Indole Alkaloids From 2-Nitrostyrene Derivatives, S M Ashikur Rahman

Graduate Theses, Dissertations, and Problem Reports (ETD)

A short and flexible synthesis of 2,3-disubstituted indoles employing a Barluenga-type palladium-catalyzed cross-coupling of p-tosylhydrazones with 2-nitroarylhalides followed by a palladium-catalyzed, carbon monoxide-mediated reductive cyclization was developed. Significantly better overall yields were obtained performing the two-step reaction sequence in a one-pot reaction. Secondly, in order to facilitate biological studies of ergotryptamine, a recently isolated ergot alkaloid, it was selected as a target for synthesis. In an attempt to synthesize ergotryptamine, a palladium catalyzed Kosugi-Migita-Stille cross coupling, a Mizoroki-Heck reaction, and a carbon monoxide-mediated palladium-catalyzed reductive cyclization were utilized as the key steps. Using a similar synthetic approach, synthesis of …

Low- And High-Wattage Vaping During Pregnancy Influence Aortic Structure And Function In Rat Offspring, James Ian Frazier

Graduate Theses, Dissertations, and Problem Reports (ETD)

Introduction: Electronic cigarettes (e-cigs) are being marketed as a healthier alternative to traditional cigarettes, yet the health consequences of e-cig usage (also called vaping) are still being investigated. E-cigs are easily customized for user preferences. For example, the choice of flavors, nicotine concentration, and/or the temperature (i.e., wattage) used to heat the e-liquid can be selected in many devices. Emerging evidence suggests that vaping during pregnancy impairs cerebral vascular function in rodent offspring. In this study, we sought to investigate the potential effects of changes to e-cig device wattage (i.e., 5W vs. 30W) with maternal vaping during pregnancy on vascular …

Evaluation Of A Comprehensive Diabetes Mellitus Protocol At A Rural, Federally Qualified Health Center In Southern West Virginia, Hannah D. Davis

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background: Diabetes mellitus is a chronic disease that affects nearly 34 million Americans. In rural Appalachia, the population is affected disproportionately at a rate of 14% compared to the national average of 10%. Diabetes is a lifelong, chronic condition managed best by a multidisciplinary team-based approach to achieve optimal disease control. Best practices in the care of diabetes support the use of evidenced based care protocols and leveraging technology to decrease the burden of disease. Type 2 diabetes mellitus (T2DM) is the most common type, making it the focal population for evaluation.

Purpose: The purpose of this project was to …

Air-Assisted Communications Using Line-Of-Sight Links, Shaikha A. Alkandari

Graduate Theses, Dissertations, and Problem Reports (ETD)

Recently, there has been a rapid increase in the use of air-assisted communications involv-
ing the use of airborne platforms such as unmanned aerial vehicles (UAVs). In air-assisted
networks, the UAVs can act like base stations in a traditional cellular network as long as an
appropriate backhaul is available. Alternatively, the UAVs could serve as relays, for instance,
connecting two ground-based users who are within range of the UAV. UAVs have the benefit
of being deployed and reconfigured rapidly and on demand.
Meanwhile, there has been a trend towards the use of higher and higher frequencies,
including those in millimeter-wave …

Bone Marrow Stroma-Induced Transcriptome Signatures Of Multiple Myeloma As Modulated By Junb, Jasleen Kaur Gandhi

Graduate Theses, Dissertations, and Problem Reports (ETD)

The bone marrow (BM) microenvironment acts as a breeding ground for drug resistance in multiple myeloma (MM). The interaction with bone marrow stromal cells (BMSCs) confer environment-mediated drug resistance (EMDR) to multiple myeloma. We investigated BM stroma-induced transcriptome signatures of MM cells through a sophisticated analysis of gene expression. In particular, we defined transcription program modulated by JunB, an emerging regulator of MM pathogenesis and a member of the transcription factor superfamily activator protein 1 (AP-1), in response to BM stimulation. The data and results lay down a foundation for future studies to illustrate the regulatory role of JunB in …

Development Of Oxide Dispersion Strengthening (Ods) Alloys Powder For Additive Manufacturing, Changyu Ma

Graduate Theses, Dissertations, and Problem Reports (ETD)

Additive manufacturing (AM) fabricated oxide dispersion strengthened (ODS) alloys are given high expectations for critical structural components such as the first stage turbine blade for their excellent creep strength and oxidation resistance compared to superalloys. However, the powder feedstock processing is still an open question since current state-of-the-art processes are not capable of achieving ultrafine strengthening elements such as Y₂O₃ in powder which leads to agglomeration issues in as-consolidated alloys. In this research, the oxidation behavior and stability of ultrafine oxide in AM-printed alloys using mechanically alloyed powders were evaluated at 1100 ^oC. In addition, a …

Development And Testing Of A Biochar Combustor For A Stirling Engine, Kyle Bryant Vickery

Graduate Theses, Dissertations, and Problem Reports (ETD)

Nonrenewable resources persist as a necessity for perpetuating the current technology and standards of living maintained throughout the world. Biochar is an alternative and renewable fuel source that constitutes the potential to provide energy comparable to coal. Designing and fabricating components that can efficiently harness biochar’s energy to power machinery would demonstrate a successful renewable energy source. The scope of this research is to explain the feasible design, fabrication, and results of technology involving the burning of biochar and transference of hot combustion products for the purpose of powering a Stirling Engine. This design consists of a solid fuel burner, …

Psychosocial Influences On And Behavioral Characteristics Of Young Adult Food Addiction, Rachel A. Wattick

Graduate Theses, Dissertations, and Problem Reports (ETD)

Introduction. Research on food addiction has increased in recent years, but there are few studies focusing on college-attending young adults, who may be at risk of developing food addiction due to the stress of the college environment. Additionally, causes and characteristics of food addiction are under-explored.

Aim. This dissertation aims to 1) determine the impact of adverse childhood experiences (ACEs) and other early life influences on the development of food addiction in college-attending young adults and 2) determine the psychosocial and behavioral characteristics of young adults with food addiction.

Methods. A sequential explanatory mixed-methods design was used for aims 1 …

Genetic Analysis And Telemetry Study Of Migration Habits Of The Endangered Atlantic Sturgeon, Cassia Marie Busch

Graduate Theses, Dissertations, and Problem Reports (ETD)

Atlantic sturgeon are a long-lived anadromous fish that ranged from Labrador, Canada to Florida, US. Due to overharvest in the late 1800’s and 1900’s, Atlantic sturgeon populations across the coast experienced a dramatic population crash. Recovery of this species has faced challenges due to anthropogenic threats, such as vessel strikes, bycatch, and habitat degradation. In 2012, Atlantic sturgeon were added to the United States Endangered Species Act (ESA). Under the ESA, populations were listed as five distinct population segments (DPS), reflecting their geographic arrangement and genetic structure: Gulf of Maine DPS (threatened), New York Bight DPS (endangered), Chesapeake DPS (endangered), …

Electrochemical And Mass Spectrometry Methods For Identification Of Gunshot Residues (Gsr) In Forensic Investigations, Kourtney A. Dalzell

Graduate Theses, Dissertations, and Problem Reports (ETD)

Gun violence continues to be one of most significant challenges straining the USA society causing thousands of human lives lost every year. In 2020 alone, firearm-related incidents including homicide, accidents, and suicides, reached a staggering number of over 43,000.^1,2 With the increase in these types of incidents, several service areas in crime laboratories are heavily impacted by the number of cases run on a yearly basis. These include firearm examinations, gunshot residue (GSR) analysis, bullet hole identification, and shooting distance determination, which are crucial to support a criminal investigation and, overall, the justice system in our country. These areas …