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Articles 37921 - 37950 of 38468
Full-Text Articles in Entire DC Network
Intelligent Techniques To Accelerate Everyday Text Communication, Jiban Krishna Adhikary
Intelligent Techniques To Accelerate Everyday Text Communication, Jiban Krishna Adhikary
Dissertations, Master's Theses and Master's Reports
People with some form of speech- or motor-impairments usually use a high-tech augmentative and alternative communication (AAC) device to communicate with other people in writing or in face-to-face conversations. Their text entry rate on these devices is slow due to their motor abilities. Making good letter or word predictions can help accelerate the communication of such users. In this dissertation, we investigated several approaches to accelerate input for AAC users. First, considering that an AAC user is participating in a face-to-face conversation, we investigated whether performing speech recognition on the speaking-side can improve next word predictions. We compared the accuracy …
Passivity-Based Numerical Modeling And Grid Integration Strategies For Wave Energy Converter Arrays, Salman Husain
Passivity-Based Numerical Modeling And Grid Integration Strategies For Wave Energy Converter Arrays, Salman Husain
Dissertations, Master's Theses and Master's Reports
The body of work presented here develops numerical time-domain models of Wave Energy Converter (WEC) arrays or wave farms. It will be shown here that a cluster of WECs can be more effective in extracting oceanic energy, can facilitate deployment logistics, and help with grid integration. The objectives of this work are: (i) developing a theoretical metric to evaluate the energy extraction potential of a WEC array, (ii) developing an algorithm that ensures the stability of the time-domain models of WEC arrays, and (iii) identifying strategies that facilitate grid integration and power management of a WEC array. In the process …
Properties And Environmental Impacts Of Sustainable Electrically Conductive Composites Of Carbonized Pulp Fibers And Recycled Polyamide 12, Chinmoyee Das
Dissertations, Master's Theses and Master's Reports
Electrically conductive composites are polymer composites filled with electrically conductive filler. Electrically conductive composites can be implemented in the development of lightweight electrically conductive components for the automotive industry. Traditional electrically conductive composites incorporate synthetic carbon-based fillers that have good properties but are very expensive and highly energy intensive, creating the need for a sustainable and cost-effective replacement. This study explores the effectiveness of biocarbon fibers developed from Douglas fir pulp fibers as a potential electrically conductive filler in recycled polyamide (PA) 12 composites.
Biocarbon fibers were developed from pulp by carbonization of the feedstock at 1000° C in an …
An Experimental Study Of Fuel Selection For A Gasoline Multi-Mode, Spark Ignited – Compression Ignition Engine, Zachary J. Stanchina
An Experimental Study Of Fuel Selection For A Gasoline Multi-Mode, Spark Ignited – Compression Ignition Engine, Zachary J. Stanchina
Dissertations, Master's Theses and Master's Reports
In this study of fuels of different reactivities and their performance in a low-temperature combustion (LTC) engine. The engine was a 2.2L CRDI engine code D4HB provided by industry partner Hyundai America Technical Center inc. (HATCI). The engine was instrumented with in-cylinder pressure sensors allowing for monitoring of the combustion process.
First, the engine was operated with standard US pump grade gasoline, Research Octane number (RON) 91 E10, to find initial operation conditions as well as control points of stable operation for daily checks on system conditions.
Tested were 8 different fuel blends, the four base blends were provided by …
Maximum Likelihood Estimator Method To Estimate Flaw Parameters For Different Glass Types, Nabhajit Goswami
Maximum Likelihood Estimator Method To Estimate Flaw Parameters For Different Glass Types, Nabhajit Goswami
Dissertations, Master's Theses and Master's Reports
Glass is commonly used in architectural applications, such as windows and in-fill panels and structural applications, such as beams and staircases. Despite the popularity of structural glass use in buildings, an engineering design standard to determine the required component or member strength for design loads does not exist. Glass is a brittle material that lacks a well-defined yield or ultimate stress, unlike ductile materials. The traditional engineering methods used to design a ductile material cannot be used to design a glass component. Glass fails in tension primarily due to the presence of microscopic flaws present on the surface that acts …
Word Games For Education: Investigating The Effectiveness Of Adding Elaboration Tasks To Crosswords For Learning Technical Vocabulary, Warat Khaewratana
Word Games For Education: Investigating The Effectiveness Of Adding Elaboration Tasks To Crosswords For Learning Technical Vocabulary, Warat Khaewratana
Dissertations, Master's Theses and Master's Reports
One challenge in STEM education is the learning of technical terms. In order to reason about higher-order scientific concepts, knowledge of technical vocabulary is often a prerequisite. Improving this knowledge may enhance the learning of higher-order concepts because it reduces cognitive load students experience while learning. To that end, we need innovative learning-aid tools that help students not only in learning and remembering technical terms, but also in applying the learned knowledge to broader concepts. This dissertation investigates the hypothesis that learning gained from crosswords can be used to teach technical terms. Furthermore, I am also examining the hypothesis that …
Study Of Electric Vehicle Smart Charging And Energy Management For Vehicle-Grid Integration Systems, Zhouquan Wu
Study Of Electric Vehicle Smart Charging And Energy Management For Vehicle-Grid Integration Systems, Zhouquan Wu
Dissertations, Master's Theses and Master's Reports
The emerging need of building an efficient Electric Vehicle (EV) charging infrastructure requires the investigation of all aspects of Vehicle-Grid Integration (VGI). This dissertation studies the optimal EV charging control and energy management of VGI system to address the economic benefits of EV charging customers and operation stability of distribution power grids. First of all, a centralized EV charging control method is developed under the transactive energy environment to minimize the EV charging cost and avoid the distribution power grid overloading. The quadratic programming is used to obtain optimized charging control actions. Case studies with hundreds of EVs are conducted …
Kinematics And Preliminary Fema P-695 Evaluation Of The Newz-Breakss Steel Boundary Frame With Buckling Restrained Brace Structural Fuses, Alexander M. Baker
Kinematics And Preliminary Fema P-695 Evaluation Of The Newz-Breakss Steel Boundary Frame With Buckling Restrained Brace Structural Fuses, Alexander M. Baker
Dissertations, Master's Theses and Master's Reports
Buckling Restrained Braced Frames (BRBFs) have become a popular seismic force resisting system (SFRS) due to their high ductility and energy dissipation. However, BRBFs are also susceptible to large residual drifts, which can make repair difficult. Efforts to reduce the residual drift of BRBFs typically involve special self-centering braces, or by using a dual system in tandem with the BRBF. This study proposes an alternative approach, in which a self-centering steel rocking frame is used as the boundary frame for the BRBF. The proposed system, called the NewZ-BREAKSS Buckling Restrained Braced Frame (NZ-BRBF) utilizes the recently proposed NewZ-BREAKSS (NZ) boundary …
Towards A Circular Economy: Liquid-Fed Fast Pyrolysis Of Waste Polyolefin Plastics, Daniel G. Kulas
Towards A Circular Economy: Liquid-Fed Fast Pyrolysis Of Waste Polyolefin Plastics, Daniel G. Kulas
Dissertations, Master's Theses and Master's Reports
Plastic usage has quickly grown in recent years as plastics have become an essential part of everyday life. Unfortunately, recycling rates have not matched the increased growth, with the majority of waste plastic landfilled. The strategy of circular economy has been proposed to reuse the waste plastic to create new polymers, thus avoiding both landfilling and the use of virgin raw materials. Achieving a circular economy for plastics requires the development of new technologies capable of recycling plastic waste under a circular economy perspective. In this dissertation, a novel liquid-fed fast pyrolysis process is introduced towards achieving a circular economy. …
Examining Cognitive Empathy Elements Within Ai Chatbots For Healthcare Systems, Lamia Alam
Examining Cognitive Empathy Elements Within Ai Chatbots For Healthcare Systems, Lamia Alam
Dissertations, Master's Theses and Master's Reports
Empathy is an essential part of communication in healthcare. It is a multidimensional concept and the two key dimensions: emotional and cognitive empathy allow clinicians to understand a patient’s situation, reasoning, and feelings clearly (Mercer and Reynolds, 2002). As artificial intelligence (AI) is increasingly being used in healthcare for many routine tasks, accurate diagnoses, and complex treatment plans, it is becoming more crucial to incorporate clinical empathy into patient-faced AI systems. Unless patients perceive that the AI is understanding their situation, the communication between patient and AI may not sustain efficiently. AI may not really exhibit any emotional empathy at …
Atomistic-Continuum Membrane And Machine Learning Models For Two-Dimensional Materials, Upenda Yadav
Atomistic-Continuum Membrane And Machine Learning Models For Two-Dimensional Materials, Upenda Yadav
Dissertations, Master's Theses and Master's Reports
“What could we do with layered structures with just the right layers?” asked Richard Feynman in his famous 1959 lecture, “There’s plenty of room at the bottom.” With the help of the amazing developments of the past several years, we are coming close to answering that question. In 2004, graphene was first isolated from graphite and only six short years later it won the Nobel Prize in Physics. Graphene is one atomic layer of Carbon, it is the thinnest and yet the strongest materials we have ever seen. It is 200 times stronger than its equivalent weight in steel and …
Permeability, Structural Changes, Flow Regime Transitions In Fuel Cell Catalyst Layers And A Model For Predicting Trapped Saturation For Two-Phase Flow In Porous Media, Karrar Takleef Alofari
Permeability, Structural Changes, Flow Regime Transitions In Fuel Cell Catalyst Layers And A Model For Predicting Trapped Saturation For Two-Phase Flow In Porous Media, Karrar Takleef Alofari
Dissertations, Master's Theses and Master's Reports
Proper water management in Proton Exchange Membrane (PEM) fuel cell is important to achieve high performance. Understanding the percolation of the produced water at the cathode catalyst layer (CL) is critical for any robust water management technique. In this study, an ex-situ experimental setup is used to study percolation in the CL at different injection rates and relative humidity (RH) conditions. The results show that increasing the flow rate force the liquid to flow through the bulk of the pores due to the dominant viscous effect. On the other hand, at low injection rates, the capillary becomes dominant and liquid …
Molecular Modeling Of High-Performance Polymers, Sagar Umesh Patil
Molecular Modeling Of High-Performance Polymers, Sagar Umesh Patil
Dissertations, Master's Theses and Master's Reports
High-performance polymers are extensively used in the aerospace and aeronautics industries due to their low density, high specific strength, and high specific stiffness. These properties along with better infiltration with reinforcements [carbon nanotubes (CNTs), glass, etc.] capability make them an excellent candidate to fabricate Polymer Matrix Composites (PMCs) tailored for specific applications. The applications range from products used daily to deep space exploration. These materials are subjected to varying temperatures and pressures during fabrication and in service. Therefore, the evolution of their intrinsic properties needs to be studied and their ability to sustain extreme environmental conditions in outer space needs …
From Thermal Springs To Subway Benches: Exploring The Diversity Of Carbon Monoxide Dehydrogenases Through Metagenomes, Phylogenetics, And Machine Learning, Isaac Bigcraft
Dissertations, Master's Theses and Master's Reports
Carbon monoxide is well known as a toxic gas but can also be an important input and intermediary for microbial metabolisms. Carbon monoxide dehydrogenases (CODHs) serve as key enzyme complexes for a variety of microbial carbon monoxide (CO) utilization pathways. Such pathways include the Wood-Ljungdahl pathway, which is important in methanogenesis and acetogenesis, metal and sulfate reduction pathways, hydrogen production, and others. The CODH enzymes allow microbes to turn the traditionally toxic waste gas of CO into a useful carbon and energy source. Despite the flexibility of CODH enzymes, the use of carbon monoxide is still believed to be a …
A Global Survey Of Volcanic So2 Emissions And Heat Flux Measured From Space, Nelmary Rodríguez-Sepúlveda
A Global Survey Of Volcanic So2 Emissions And Heat Flux Measured From Space, Nelmary Rodríguez-Sepúlveda
Dissertations, Master's Theses and Master's Reports
Over the past two decades, the availability of satellite measurements of volcanic gas emissions and heat flux has driven the development of new methodologies to improve global-scale volcano monitoring. In this work we explored the relationship between volcanic sulfur dioxide (SO2) emissions and radiant heat flux (RHF) measurements from NASA’s Ozone Monitoring Instrument (OMI) and Moderate Resolution Imaging Spectroradiometer (MODIS), respectively, to gain insight into how it associates to volcanic processes and eruption styles. The OMI SO2 emissions data are derived from existing databases developed by using the methodology in Fioletov et al. (2016), which contain global, …
Partially Stratified Combustion Of Natural Gas For Spark Ignition Engines, Philip S. Zoldak
Partially Stratified Combustion Of Natural Gas For Spark Ignition Engines, Philip S. Zoldak
Dissertations, Master's Theses and Master's Reports
In this work, the advantages of partially stratified direct injection natural gas versus premixed port-fueled injection natural gas spark ignited engines has been studied. The volumetric efficiency, ratio of specific heats and turbulent kinetic energy was found to be higher with direct injection versus port-fueled injection thus improving thermal efficiency. A background study of optical chamber experimental data was performed to develop an understanding on the effect of pressure ratio on direct injection of methane under both fully-expanded (sub-sonic) and under-expanded (super-sonic) conditions. Under-expanded jets had a noticeable advantage in terms of turbulent kinetic energy, which led to enhanced air …
Collective Hydrodynamics Of Robotic Fish, Rohit S. Pandhare
Collective Hydrodynamics Of Robotic Fish, Rohit S. Pandhare
Dissertations, Master's Theses and Master's Reports
Many animals in nature travel in groups either for protection, survival, or endurance. Among these, fish do so under the burden of hydrodynamic loads, which incites questions as to the significance of the multi-body fluid-mediated interactions that facilitate collective swimming. We study such interactions in the idealized setting of a rotational array of robotic fish whose tails undergo a prescribed flapping motion, but whose swimming speed is determined as a natural result of the hydrodynamic effects. Specifically, we examine how the measured collective speed of the swimmers varies with the imposed frequency and amplitude of their tail flapping, and with …
Recovering And Upgrading Kraft Lignin For Application In Flexible Polyurethane Foam, Peng Quan
Recovering And Upgrading Kraft Lignin For Application In Flexible Polyurethane Foam, Peng Quan
Dissertations, Master's Theses and Master's Reports
Lignin is the second abundant natural polymer and has been highlighted as a potential substitute for fossil-based raw materials. However, the inherent molecular heterogeneity and the complex recovery processes result in the challenge of controlling the molecular properties and value-added applications of lignin in large scale. To address those issues, a novel acid-liquefaction process was developed in this study to recover Kraft lignin with improved molecular homogeneity directly from black liquor.
In the first study, the liquefaction parameters were screened based on yield and molecular weight properties of the recovered lignin. Then, the recovered lignin samples were used to replace …
Optimal Control Of Nonlinear Wave Energy Converters In Heave For Maximum Power Extraction, Kevin Nelson
Optimal Control Of Nonlinear Wave Energy Converters In Heave For Maximum Power Extraction, Kevin Nelson
Dissertations, Master's Theses and Master's Reports
The marine renewable energy community is interested in maximizing the power generated by nonlinear wave energy converters. Optimal control methods provide a tool to achieve this aim and can also help to inform the buoy design. An energy-optimal control law for a class of non-linear buoy models is derived and is shown to be singular. The solution approach is illustrated using an hourglass-shaped buoy having a cubic, hydrostatic nonlinearity. The optimal control law is only valid on singular arcs, and a method to search for these arcs is presented. Two singular arcs are found for the hourglass buoy model and …
Improving Energy Stewardship At Michigan Technological University’S Athletic Complexes, Cynthia L. Pindral
Improving Energy Stewardship At Michigan Technological University’S Athletic Complexes, Cynthia L. Pindral
Dissertations, Master's Theses and Master's Reports
Athletics departments are showcases for universities, serving as a public face and recruitment outlet that communicates university identity to the world. This applied research project examines the state of electrical energy infrastructure at Michigan Technological University with special attention to the Athletic Department and reports on the process for energy decisions in both settings. I take a qualitative research approach analyzing University documents and conducting interviews with informants in Athletics Administration, Facilities, and MTU’s Office of Sustainability and Resilience. Four major barriers to efficiency emerged: (1) lack of University-wide climate action goals, (2) staffing issues due to a large number …
Concept Evaluation And Development Of A Novel Approach For Integration Of Turbogeneration, Electrification And Supercharging On Heavy Duty Engines, Satyum Joshi
Dissertations, Master's Theses and Master's Reports
While many technologies such as electrically assisted turbocharging, exhaust energy recovery and mild hybridization have already proven to significantly increase heavy-duty engine efficiency, the key challenge to their widespread adoption has been their cost effectiveness and packaging. This research specifically addresses these challenges through evaluation and development of a novel technology concept termed as the Integrated Turbogeneration, Electrification and Supercharging (ITES) system. The concept integrates a secondary compressor, a turbocompound/expander turbine and an electric motor through a planetary gearset into the engine cranktrain. The approach enables a reduced system cost and space-claim, while maximizing the efficiency benefits of independent technologies. …
Design And Real-Time Implementation Of Optimal Model-Based Torque Shaping Automotive Control Systems, G. V. Prithvi Reddy
Design And Real-Time Implementation Of Optimal Model-Based Torque Shaping Automotive Control Systems, G. V. Prithvi Reddy
Dissertations, Master's Theses and Master's Reports
The presence of backlash and compliance in automotive drivelines can lead to undesirable NVH phenomena known as clunk and shuffle, respectively, which severely deteriorates the drivability of the vehicle. Since the backlash and compliance are design choices for automotive drivelines, they cannot be completely eliminated. Therefore, torque shaping control systems are used to appropriately modulate the torque commands sent to automotive actuators under different operating conditions in order to reduce clunk and shuffle. Model-based controllers provide good control performance without the need for cumbersome calibrations and long development time. Consequently, this dissertation centers on the design and real-time implementation of …
Length-Scale-Dependent Stress Relief Mechanisms In High Purity Indium, Fereshteh Mallakpour
Length-Scale-Dependent Stress Relief Mechanisms In High Purity Indium, Fereshteh Mallakpour
Dissertations, Master's Theses and Master's Reports
Lithium-ion batteries are widely used in portable electronics and electric vehicles. However, due to the presence of flammable liquid electrolytes, these devices fail catastrophically when the cell experiences a short circuit. One attractive solution to this problem is a solid-state battery. As the name implies, the flammable liquid electrolyte is replaced by a non-flammable solid-state electrolyte (SSE). The unexpected, yet frequently observed failure mechanism in these devices is the formation and growth of lithium dendrites originating at the interface between the lithium anode and the SSE. As the dendrites grow, device performance degrades. Once the dendrites completely penetrate the SSE, …
Understanding Strength Of Dried Iron Ore Pellets, Victor Claremboux
Understanding Strength Of Dried Iron Ore Pellets, Victor Claremboux
Dissertations, Master's Theses and Master's Reports
After an extensive literature review, it was found that there was no reliable way for predicting the impact of binders or mixtures of binders on iron ore pellets. This is a challenging problem because iron ore pellets are a complex product of an agglomeration process which is typically controlled only to the extent that is necessary to form a quality product for ironmaking. This work identifies the resistance of a dried pellet to abrasion as a prime variable to record and analyze to understand the influence of combined pellet binders. A consistent method of measuring abrasion resistance is identified and …
Why Test Results Are Still Getting "Lost" To Follow-Up: A Qualitative Study Of Implementation Gaps, Andrew J Zimolzak, Umber Shahid, Traber D Giardina, Sahar A Memon, Umair Mushtaq, Lisa Zubkoff, Daniel R Murphy, Andrea Bradford, Hardeep Singh
Why Test Results Are Still Getting "Lost" To Follow-Up: A Qualitative Study Of Implementation Gaps, Andrew J Zimolzak, Umber Shahid, Traber D Giardina, Sahar A Memon, Umair Mushtaq, Lisa Zubkoff, Daniel R Murphy, Andrea Bradford, Hardeep Singh
Faculty, Staff and Students Publications
BACKGROUND: Lack of timely follow-up of abnormal test results is common and has been implicated in missed or delayed diagnosis, resulting in potential for patient harm.
OBJECTIVE: As part of a larger project to implement change strategies to improve follow-up of diagnostic test results, this study sought to identify specifically where implementation gaps exist, as well as possible solutions identified by front-line staff.
DESIGN: We used a semi-structured interview guide to collect qualitative data from Veterans Affairs (VA) facility staff who had experience with test results management and patient safety.
SETTING: Twelve VA facilities across the USA.
PARTICIPANTS: Facility staff …
Steroid Receptor Coactivators – Their Role In Immunity, Yosi Gilad, David M Lonard, Bert W O'Malley
Steroid Receptor Coactivators – Their Role In Immunity, Yosi Gilad, David M Lonard, Bert W O'Malley
Faculty, Staff and Students Publications
Steroid Receptor Coactivators (SRCs) are essential regulators of transcription with a wide range of impact on human physiology and pathology. In immunology, SRCs play multiple roles; they are involved in the regulation of nuclear factor-κB (NF-κB), macrophage (MΦ) activity, lymphoid cells proliferation, development and function, to name just a few. The three SRC family members, SRC-1, SRC-2 and SRC-3, can exert their immunological function either in an independent manner or act in synergy with each other. In certain biological contexts, one SRC family member can compensate for lack of activity of another member, while in other cases one SRC can …
Proceedings Of The 10th Annual Deep Brain Stimulation Think Tank: Advances In Cutting Edge Technologies, Artificial Intelligence, Neuromodulation, Neuroethics, Interventional Psychiatry, And Women In Neuromodulation, Joshua K Wong, Helen S Mayberg, Doris D Wang, R Mark Richardson, Casey H Halpern, Lothar Krinke, Mattia Arlotti, Lorenzo Rossi, Alberto Priori, Sara Marceglia, Ro'ee Gilron, James F Cavanagh, Jack W Judy, Svjetlana Miocinovic, Annaelle D Devergnas, Roy V Sillitoe, Stephanie Cernera, Carina R Oehrn, Aysegul Gunduz, Wayne K Goodman, Erika A Petersen, Helen Bronte-Stewart, Robert S Raike, Mahsa Malekmohammadi, David Greene, Petra Heiden, Huiling Tan, Jens Volkmann, Valerie Voon, Luming Li, Pankaj Sah, Terry Coyne, Peter A Silburn, Cynthia S Kubu, Anna Wexler, Jennifer Chandler, Nicole R Provenza, Sarah R Heilbronner, Marta San Luciano, Christopher J Rozell, Michael D Fox, Coralie De Hemptinne, Jaimie M Henderson, Sameer A Sheth, Michael S Okun
Proceedings Of The 10th Annual Deep Brain Stimulation Think Tank: Advances In Cutting Edge Technologies, Artificial Intelligence, Neuromodulation, Neuroethics, Interventional Psychiatry, And Women In Neuromodulation, Joshua K Wong, Helen S Mayberg, Doris D Wang, R Mark Richardson, Casey H Halpern, Lothar Krinke, Mattia Arlotti, Lorenzo Rossi, Alberto Priori, Sara Marceglia, Ro'ee Gilron, James F Cavanagh, Jack W Judy, Svjetlana Miocinovic, Annaelle D Devergnas, Roy V Sillitoe, Stephanie Cernera, Carina R Oehrn, Aysegul Gunduz, Wayne K Goodman, Erika A Petersen, Helen Bronte-Stewart, Robert S Raike, Mahsa Malekmohammadi, David Greene, Petra Heiden, Huiling Tan, Jens Volkmann, Valerie Voon, Luming Li, Pankaj Sah, Terry Coyne, Peter A Silburn, Cynthia S Kubu, Anna Wexler, Jennifer Chandler, Nicole R Provenza, Sarah R Heilbronner, Marta San Luciano, Christopher J Rozell, Michael D Fox, Coralie De Hemptinne, Jaimie M Henderson, Sameer A Sheth, Michael S Okun
Faculty, Staff and Students Publications
The deep brain stimulation (DBS) Think Tank X was held on August 17–19, 2022 in Orlando FL. The session organizers and moderators were all women with the theme women in neuromodulation. Dr. Helen Mayberg from Mt. Sinai, NY was the keynote speaker. She discussed milestones and her experiences in developing depression DBS. The DBS Think Tank was founded in 2012 and provides an open platform where clinicians, engineers and researchers (from industry and academia) can freely discuss current and emerging DBS technologies as well as the logistical and ethical issues facing the field. The consensus among the DBS Think …
Evaluation Of The Clinical Effectiveness Of Modified Sacrospinous Ligament Fixation, Yuanyuan Lyu, Huafeng Ding, Ying Zhang, Suhua Shi, Jin Ding, Chengcheng Zhu, Xiaoming Guan, Guantai Ni, Yonghong Luo
Evaluation Of The Clinical Effectiveness Of Modified Sacrospinous Ligament Fixation, Yuanyuan Lyu, Huafeng Ding, Ying Zhang, Suhua Shi, Jin Ding, Chengcheng Zhu, Xiaoming Guan, Guantai Ni, Yonghong Luo
Faculty, Staff and Students Publications
OBJECTIVE: To describe the surgical techniques and short-term outcomes for 50 cases of modified sacrospinous ligament fixation
METHODS: 100 patients with pelvic organ prolapse (stage III or stage IV based on POP-Q staging) from January 2018 to January 2020 were retrospectively analyzed. Among them, 50 patients received modified sacrospinous ligament fixation via the anterior vaginal wall path for pelvic organ prolapse (mSSLF group), while the other 50 patients received pelvic reconstruction using T4 mesh (T4 group). Operative time, blood loss, postoperative POP-Q score, length of the hospital stay, complications, and postoperative pain were compared between the two groups.
RESULTS: The …
The Third International Hackathon For Applying Insights Into Large-Scale Genomic Composition To Use Cases In A Wide Range Of Organisms, Kimberly Walker, Divya Kalra, Rebecca Lowdon, Guangyi Chen, David Molik, Daniela C Soto, Fawaz Dabbaghie, Ahmad Al Khleifat, Medhat Mahmoud, Luis F Paulin, Muhammad Sohail Raza, Susanne P Pfeifer, Daniel Paiva Agustinho, Elbay Aliyev, Pavel Avdeyev, Enrico R Barrozo, Sairam Behera, Kimberley Billingsley, Li Chuin Chong, Deepak Choubey, Wouter De Coster, Yilei Fu, Alejandro R Gener, Timothy Hefferon, David Morgan Henke, Wolfram Höps, Anastasia Illarionova, Michael D Jochum, Maria Jose, Rupesh K Kesharwani, Sree Rohit Raj Kolora, Jędrzej Kubica, Priya Lakra, Damaris Lattimer, Chia-Sin Liew, Bai-Wei Lo, Chunhsuan Lo, Anneri Lötter, Sina Majidian, Suresh Kumar Mendem, Rajarshi Mondal, Hiroko Ohmiya, Nasrin Parvin, Carolina Peralta, Chi-Lam Poon, Ramanandan Prabhakaran, Marie Saitou, Aditi Sammi, Philippe Sanio, Nicolae Sapoval, Najeeb Syed, Todd Treangen, Gaojianyong Wang, Tiancheng Xu, Jianzhi Yang, Shangzhe Zhang, Weiyu Zhou, Fritz J Sedlazeck, Ben Busby
The Third International Hackathon For Applying Insights Into Large-Scale Genomic Composition To Use Cases In A Wide Range Of Organisms, Kimberly Walker, Divya Kalra, Rebecca Lowdon, Guangyi Chen, David Molik, Daniela C Soto, Fawaz Dabbaghie, Ahmad Al Khleifat, Medhat Mahmoud, Luis F Paulin, Muhammad Sohail Raza, Susanne P Pfeifer, Daniel Paiva Agustinho, Elbay Aliyev, Pavel Avdeyev, Enrico R Barrozo, Sairam Behera, Kimberley Billingsley, Li Chuin Chong, Deepak Choubey, Wouter De Coster, Yilei Fu, Alejandro R Gener, Timothy Hefferon, David Morgan Henke, Wolfram Höps, Anastasia Illarionova, Michael D Jochum, Maria Jose, Rupesh K Kesharwani, Sree Rohit Raj Kolora, Jędrzej Kubica, Priya Lakra, Damaris Lattimer, Chia-Sin Liew, Bai-Wei Lo, Chunhsuan Lo, Anneri Lötter, Sina Majidian, Suresh Kumar Mendem, Rajarshi Mondal, Hiroko Ohmiya, Nasrin Parvin, Carolina Peralta, Chi-Lam Poon, Ramanandan Prabhakaran, Marie Saitou, Aditi Sammi, Philippe Sanio, Nicolae Sapoval, Najeeb Syed, Todd Treangen, Gaojianyong Wang, Tiancheng Xu, Jianzhi Yang, Shangzhe Zhang, Weiyu Zhou, Fritz J Sedlazeck, Ben Busby
Faculty, Staff and Students Publications
In October 2021, 59 scientists from 14 countries and 13 U.S. states collaborated virtually in the Third Annual Baylor College of Medicine & DNANexus Structural Variation hackathon. The goal of the hackathon was to advance research on structural variants (SVs) by prototyping and iterating on open-source software. This led to nine hackathon projects focused on diverse genomics research interests, including various SV discovery and genotyping methods, SV sequence reconstruction, and clinically relevant structural variation, including SARS-CoV-2 variants. Repositories for the projects that participated in the hackathon are available at https://github.com/collaborativebioinformatics.
Rotavirus-Induced Lipid Droplet Biogenesis Is Critical For Virus Replication, Jeanette M Criglar, Mary K Estes, Sue E Crawford
Rotavirus-Induced Lipid Droplet Biogenesis Is Critical For Virus Replication, Jeanette M Criglar, Mary K Estes, Sue E Crawford
Faculty, Staff and Students Publications
A variety of pathogens, including viruses, bacteria and parasites, target cellular lipid droplets for their replication. Rotaviruses (RVs) infect the villous epithelium of the small intestine and are a major cause of acute gastroenteritis in infants and young children worldwide. RVs induce and require lipid droplets for the formation of viroplasms, sites of virus genome replication, and nascent particle assembly. Here we review the role of lipid droplets in RV replication. Inhibitors of fatty acid synthesis or chemicals that interfere with lipid droplet homeostasis decrease the number and size of viroplasms and the yield of infectious virus. We used a …