Digital Commons Network^™

Tres Padres Y Una Lección, Tim Olson

CouRaGeouS Cuentos: A Journal of Counternarratives

No abstract provided.

Icsm 3rd Annual Scientific Meeting Plenary Lectures

Journal of the Hong Kong College of Cardiology

No abstract provided.

News, Notes, & Correspondence

Spring: The Journal of the E. E. Cummings Society

No abstract provided.

Plotting The Evolution Of A ”R-P-O-P-H-E-S-S-A-G-R”, Michael Webster

Spring: The Journal of the E. E. Cummings Society

No abstract provided.

Final Draft Of Fountain Plaque Text, Fort Hays State University

Buildings & Facilities

This black and white document features a final draft of the text for the fountains dedication plaque.

Haemosporidian Parasite Diversity In An Under-Surveyed Australian Avifauna, Ian R. Hoppe, Allison E. Johnson, Elizabeth Vanwormer

School of Natural Resources: Faculty Publications

Haemosporidian parasites of birds are geographically widespread, have been detected in a phylogenetically diverse array of hosts, and have been the focus of extensive research due to both their impacts on birds and their similarity to vector-borne diseases of humans. Advances in molecular diagnostic tools have created a greater awareness of the genetic diversity of haemosporidian infections. Yet in spite of their more or less global distribution, comparatively little is known about the haemosporidians affecting birds in Australia. We screened blood from 889 birds (23 species) for haemosporidian blood parasite infections during the 2019 breeding season at Brookfield Conservation Park, …

Medical School Watercooler Newsletter - July 28, 2022, Lindsey Lyle

Watercooler Newsletter

This is the July 28, 2022 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents include:

• Meet a Med Student: Jonathan Trinh
• Whiddon College of Medicine welcomes largest incoming class
• Participants needed for NIH-sponsored research project on long COVID
• Whiddon College of Medicine alumni win Nappie Awards
• Macaluso recognized for service to American Society for Rickettsiology

Music: Seeking Pleasure, Emotional Language, Ritualized Communication, Jillian N. Gerlach

Interdivisional Studies Summer Fellows

The impetus for my project was how I view listening to music as a spiritual or religious experience. Listening to music, instead of practicing religion, satisfies my inclination toward spirituality. In the introduction to my paper, I outlined how music exists in my life. I thought it was valuable to provide my unique experience to give context to my research. I created a diagram that delineates how I interact with music and the benefits I derive from listening to music. During this self-reflection, I realized listening to music functions like a ritual for me. I noticed my individual ritualized listening …

Protein Shape Sampled By Ion Mobility Mass Spectrometry Consistently Improves Protein Structure Prediction, Micah T. Donor, Sm Bargeen Alam Turzo, Justin T. Seffernick, Amber D. Rolland, Stein Heinze, James S. Prell, Vicki H. Wysocki, Steffen Lindert

Faculty Publications - Department of Biological & Molecular Science

Ion mobility (IM) mass spectrometry provides structural information about protein shape and size in the form of an orientationally-averaged collision cross-section (CCSIM). While IM data have been used with various computational methods, they have not yet been utilized to predict monomeric protein structure from sequence. Here, we show that IM data can significantly improve protein structure determination using the modelling suite Rosetta. We develop the Rosetta Projection Approximation using Rough Circular Shapes (PARCS) algorithm that allows for fast and accurate prediction of CCSIM from structure. Following successful testing of the PARCS algorithm, we use an integrative modelling approach to utilize …

Carey Snyder’S Take On ‘Ann Veronica’ By H.G. Wells Provides Window To Discuss Women’S Lives Today, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Computing Well-Structured Subgraphs In Geometric Intersection Graphs., Satyabrata Jana Dr.

Doctoral Theses

For a set of geometric objects, the associative geometric intersection graph is the graph with a vertex for each object and an edge between two vertices if and only if the corresponding objects intersect. Geometric intersection graphs are very important due to their theoretical properties and applicability. Based on the different geometric objects, several types of geometric intersection graphs are defined. Given a graph G, an induced (either vertex or edge) subgraph H ⊆ G is said to be an well-structured subgraph if H satisfies certain properties among the vertices in H. This thesis studies some well-structured subgraphs finding problems …

Generation And Computational Characterization Of A Complex Staphylococcus Aureus Lipid Bilayer, Faramarz Joodaki, Lenore M. Martin, Michael L. Greenfield

Chemical, Biomolecular, and Materials Engineering Faculty Publications

Studies indicate a crucial cell membrane role in the antibiotic resistance of Staphylococcus aureus. To simulate its membrane structure and dynamics, a complex molecular-scale computational representation of the S. aureus lipid bilayer was developed. Phospholipid types and their amounts were optimized by reverse Monte Carlo to represent characterization data from the literature, leading to 19 different phospholipid types that combine three headgroups [phosphatidylglycerol, lysyl-phosphatidylglycerol (LPG), and cardiolipin] and 10 tails, including iso- and anteiso-branched saturated chains. The averaged lipid bilayer thickness was 36.7 Å, and area per headgroup was 67.8 Ų. Phosphorus and nitrogen density profiles showed …

Biosimilar Bias: A Barrier To Addressing American Drug Costs, Cynthia M. Ho

Denver Law Review

Forty percent of spiraling drug costs in the United States stem from a mere 2% of all drugs—biologic drugs (biologics) made from living cells and administered by injection or infusion. Drug costs will continue to rise as new biologics are approved by the Food and Drug Administration. Biologics are expensive because they cannot be mass-produced, and the consequence of their high prices is that important treatments for conditions such as arthritis and cancer remain out of reach for many Americans. Fortunately, just as there are lower cost generic versions of brand-name pills, there are lower cost biosimilars of original biologics—the …

Implication Of Melanocortin Receptor Genes In The Familial Comorbidity Of Type 2 Diabetes And Depression., Mutaz Amin, Jurg Ott, Rongling Wu, Teodor T Postolache, Claudia Gragnoli

Division of Endocrinology, Diabetes and Metabolic Diseases Faculty Papers

The melanocortin receptors are G-protein-coupled receptors, which are essential components of the hypothalamic–pituitary–adrenal axis, and they mediate the actions of melanocortins (melanocyte-stimulating hormones: α-MSH, β-MSH, and γ-MSH) as well as the adrenocorticotropin hormone (ACTH) in skin pigmentation, adrenal steroidogenesis, and stress response. Three melanocortin receptor genes (MC1R, MC2R, and MC5R) contribute to the risk of major depressive disorder (MDD), and one melanocortin receptor gene (MC4R) contributes to the risk of type 2 diabetes (T2D). MDD increases T2D risk in drug-naïve patients; thus, MDD and T2D commonly coexist. The five melanocortin receptor genes might confer risk for both disorders. However, they …

2022-July-28-Enjoy Retirement, University Marketing And Communication, East Tennessee State University

ETSU News

Congratulations to the following members of the East Tennessee State University family who retired in July. Thank you for your service!

Robert R. Beach, Jr. – Senior Lecturer, Economics and Finance, 11 years of service

James Bitter – Professor, Counseling and Human Services, 26 years of service

Deborah Dotson – Professor, Allied Health (Dental Hygiene), 36 years of service

Tammy Hayes – Assistant professor, Media and Communication, 27 years of service

Joel Hillhouse – Professor, Community and Behavioral Health/Associate Dean for Research, College of Public Health, 31 years of service

Thomas Laughlin – Associate Professor, Biological Sciences, 18 years of …

Chemical And Biological Stressors Threaten Native Fish Diversity In The Spring River Subbasin Of Kansas, Alexandra King

Electronic Theses & Dissertations

Chemical pollution and nonnative species are two of the major threats facing freshwater fishes. As such, understanding how freshwater fish communities respond to pollution remediation efforts and nonnative fish introductions are primary goals of native fish conservation. Within the Spring River subbasin (SRS) of southeastern Kansas, this study examined the long-term response of riffle fish communities to decreases in heavy metal concentrations, as well as the effects of introduced Blackspotted Topminnow (Fundulus olivaceus) on native Blackstripe Topminnow (Fundulus notatus). The objectives of our research in Chapter 01 of this thesis were to quantify changes in riffle …

The Role Of Nest Location On The Reproductive Success Of Piping Plovers Breeding At Rockaway Beach, New York, Clara I.D. Arndtsen

Theses and Dissertations

The study’s goal was to learn what aspects of the piping plover experience affect reproductive outcomes at Rockaway Beach Endangered Species Nesting Area. Nest location was found to help predict reproductive success. Nests further from American oystercatcher nests were likely to fledge more chicks. Reproductive success was low in 2021.

Gaze In Cats And Dogs, Michael Bogese

Theses and Dissertations

Domestic dogs (Canis lupus familiaris) developed many behaviors across domestication, one example being gaze behavior. Gaze is the crux of other behaviors that make dogs unique in human-animal dyads, including lookbacks, gaze-following, and participation in an oxytocin feedback loop. Gaze behavior may have been motivated and sustained by evergreen cooperative relationships between dogs and humans (e.g., hunting, service roles). One way to confirm this relationship is to compare dogs to a domesticated species that lacks a protracted history of companionship: the domestic cat (Felis catus). In this study, we compare the gaze duration to owners of …

Problem Solving In Chelonia With Comments On Behavior And Methodological Challenges, Mal Walton

Theses and Dissertations

This study presented, to a variety of Chelonia species, a one-solution puzzle box problem. Of the 15 turtles tested, 11 solved the task at least once. Because studies on problem solving in reptiles, specifically Chelonia, are relatively unprecedented, we provide an examination of our methodology, along with suggestions for improvement.

Pervasive Healthcare Internet Of Things: A Survey, Kim Anh Phung, Cemil Kirbas, Leyla Dereci, Tam Van Nguyen

Computer Science Faculty Publications

Thanks to the proliferation of the Internet of Things (IoT), pervasive healthcare is gaining popularity day by day as it offers health support to patients irrespective of their location. In emergency medical situations, medical aid can be sent quickly. Though not yet standardized, this research direction, healthcare Internet of Things (H-IoT), attracts the attention of the research community, both academia and industry. In this article, we conduct a comprehensive survey of pervasive computing H-IoT. We would like to visit the wide range of applications. We provide a broad vision of key components, their roles, and connections in the big picture. …

Limited Effects Of Precipitation Manipulation On Soil Respiration And Inorganic N Concentrations Across Soil Drainage Classes In Northern Minnesota Aspen Forests, Anna B. Stockstad, Robert A. Slesak, Alan J. Toczydlowski, Charles R. Blinn, Randall K. Kolka, Stephen D. Sebestyen

Aspen Bibliography

It is critical to gain insight into the responses of forest soils to the changing climate. We simulated future climate conditions with growing season throughfall reduction (by 50%) and winter snow removal using a paired-plot design across a soil drainage class gradient at three upland, Populus-dominated forests in northern Minnesota, USA. In situ bulk soil respiration and concentrations of extractable soil N were measured during the summers of 2020–2021. Soil respiration and N concentrations were not affected by throughfall reduction and snow removal, which was largely attributed to the limited treatment effects on soil moisture content and soil temperature. …

The Diatom Dark Ages: Identification Of Mid-Cretaceous Arctic Platform Diatoms From The Basal Transgression Of The Kanguk Formation, Devon Island, Nunavut, Canada, Megan Heins

Department of Earth and Atmospheric Sciences: Dissertations, Theses, and Student Research

The lower part of the mid-Cretaceous Kanguk Formation (Lower Turonian interval) contains an important paleontological record crucial to the characterization of a poorly known interval of fossil marine diatoms history. Kanguk Formation mudstones are exposed in a ~200 m-thick section on Devon Island, Nunavut, Canadian High Arctic. Diatoms at this location are well-preserved due to shallow burial on this Arctic Platform site. The rock sequence was protected from glacial erosion that removed much of the Cretaceous record by being down-faulted in a linear graben. Study of these well-preserved fossil diatoms allows for a documentation of the assemblage, identification of potentially …

Coupling Dendrochronology And Remote Sensing Techniques To Assess The Biophysical Traits Of Juniperus Virginiana And Pinus Ponderosa Within Grassland Communities In The Semi-Arid Grasslands Of The Nebraska Sandhills, Reece Allen

School of Natural Resources: Dissertations, Theses, and Student Research

Woody species encroachment is occurring within the sandhills region in Nebraska, primarily driven by Juniperus virginiana and Pinus ponderosa, altering ecosystems and the services they provide. Effective, low cost, and cross-scale monitoring of woody species growth and performance is necessary for integrated grassland and forest management in the face of climate variability and change. In this study, we sought to establish a relationship between remote sensing-derived vegetation indices (VIs) and dendrochronological (raw and standardized tree ring width) measurements to assess the performance of encroaching woody J. virginiana and P. ponderosa located within the Nebraska National Forest in the sandhills. …

The Intersections Of Migration And Identity In Young Adult Literature Of The French-Speaking World, Kaitlyn Waller

Department of Modern Languages and Literatures: Dissertations, Theses, and Student Research

Both young adult literature and novels of migration frequently deal with the construction of identity, from coming-of-age stories to narratives of intercultural exploration and hybridization. Young adult narratives of migration, then, represent a fascinating intersection of two literary traditions for the exploration of questions of identity. However, young adult literature and its varied subgenres are often overlooked among the broader critical scholarship of migration narratives. Indeed, the genre is often critiqued as too simplistic or pedagogical to truly merit consideration among adult readers and academics. Through an in-depth analysis of nine novels, however, I explore questions of identity development in …

Registration Of Lcs ‘Valiant’ Hard Red Winter Wheat, P. Stephen Baenziger, S. D. Masterson, J. D. Boehm Jr., Vikas Belamkar, M. D. Barnett, Devin J. Rose, Lan Xu, Stephen N. Wegulo, T. Regassa, Amanda Easterly, Cody F Creech, Dipak K. Santra, G. R. Kruger, G. W. Hergert, R. N. Klein, J. Kolmer, J. Kolmer, M.-S. Chen, Gary L. Hein, R. L. Bowden, M. J. Guttieri, G. Bai, El-Basyoni Salah, J. Poland

Department of Agronomy and Horticulture: Faculty Publications

Historically cultivars developed jointly by the University of Nebraska-Lincoln and USDA-ARS wheat (Triticum aestivum L.) improvement project tend to be late and better adapted to the northern Great Plains. LCS ‘Valiant’ (Reg. no. CV-1196, PI 693223; tested as NE10478-1) was released based on the merits of its earliness, agronomic performance, relevant disease resistances, and end-use quality characteristics and its adaptation to the central Great Plains. As such, the line was licensed to Limagrain Cereal Seeds for their ability to market outside of Nebraska. LCS Valiant hard red winter wheat was released in March 2020 by the developing institutions and …

Simulating Sub-Threshold Communication Channels Through Neurons, Richard Maina

School of Computing: Dissertations, Theses, and Student Research

Molecular Communication is an emerging paradigm with the potential to revolutionize the technology behind wearable and implantable devices and the broad range of functions they support, from tracking physical activity to medical diagnostics. This can be achieved through intra-body communication networks that take advantage of natural biological processes as a means of transmitting, propagating and receiving information. In this thesis we focus particularly on using the neuron as a means to facilitate information transfer for interconnected wearable or implantable devices through a technique known as sub-threshold electrical stimulation. We develop upon a prior work by introducing a linear model of …

Understanding The Role Of Antioxidant Nanoparticles In Improving The Outcome Of Secondary Injury In Traumatic Brain Injury, Aria W. Tarudji

Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research

Following traumatic brain injury (TBI), excess reactive oxygen species (ROS) and other free radicals are released, inducing the cascade of secondary injury that exacerbate the outcomes of TBI. Antioxidant nanoparticles (ANPs) have shown promising outcomes in reducing the progression of TBI, which may be due to the higher accumulation and retention of ANPs in the injured brain. However, there is limited knowledge of: 1) antioxidant activities needed in TBI treatment, 2) correlation between longer retention, bioavailability, and target engagement with antioxidant treatments, and 3) sexual dimorphism to ANP treatments.

This dissertation assesses multiple ANPs with various scavenging activities and durations …

Feedback And Spider Size Estimation: A Quantitative Investigation Into Whether Fear And Feedback Influences Size Estimation In Spiders, Amelia Clements

The Plymouth Student Scientist

This paper investigated the link between trait fear in spider phobic participants and size estimation of an imagined spider. However, previous research has suggested that there is a strong association between fear and size estimation bias in phobic individuals, which could be mediating spider phobia. To reduce this bias, false verbal feedback was given to spider phobic participants to test whether spider size estimation can be reduced through convincing participants that they are less afraid of spiders than the average person. Participants were either in the no feedback or feedback condition. The feedback condition were told that they are less …

Investigating Metformin & Syrosingopine's Synthetic Lethality In Pc3 & Thp-1 Cancer Cell Lines, Sophia V. Medeiros

The Plymouth Student Scientist

The oral antidiabetic, metformin, has been documented to have antineoplastic activity in various cancer cell lines, associated with the inhibition of mitochondrial complex I. However, pre-clinical studies have struggled to demonstrate such antineoplastic activity utilising metformin concentrations attainable with standard antidiabetic dosing. Research has revealed that metformin combined with the anti-hypertensive drug, syrosingopine, lowers metformin’s therapeutic threshold and sensitizes cancer cells to killing, by inhibiting monocarboxylate transporters (MCT)1/MCT4. The potent interaction between these drugs elicits a synthetic lethality, specific to transformed cells. This preliminary study aimed to investigate metformin’s antineoplastic effects and its synergistic relationship with syrosingopine by measuring cell …

Finite Element Analysis Of A Total Wrist Replacement: Determining Implant Lifetime Due To Fatigue, Edward Alton

The Plymouth Student Scientist

Total wrist replacement is a surgery in which an implant is used to help a patient regain a full range of painless movement in their wrist. However, there is little data to suggest the lifetime of implants when being used, implants should last as long as possible to reduce possible harm to patients and reduce the need of more surgery. This paper aims to use finite element analysis (FEA) to develop a model of a total wrist replacement and therefore develop a fatigue analysis based on the typical use of the implant. Results from the FEA were further corroborated using …