Digital Commons Network^™

Characterization And Classification Of Estuarine Suspended Particles Based On Their Inorganic/Organic Matter Composition, Z Safar, C Chassagne, S Rijnsburger, Mi Sanz, Aj Manning, Aj Souza, Kessel T Van, A Horner-Devine, R Flores, M Mckeon, Jd Pietrzak

School of Biological and Marine Sciences

An 11 hours survey was performed on the 17th of September 2014 in the Rhine Region Of Freshwater Influence (Rhine-ROFI) about 10 km downstream of the mouth of the Rotterdam Waterway during calm weather conditions. Suspended Particle Matter (SPM) measurements were performed during a full tidal cycle, near the seabed, at neap tide, and samples were taken at 0.6 meter above bed for on-board analysis. The measurements were performed with (a) LISST 100X, a submersible particle size analyzer, (b) LISST-HOLO, a submersible digital holographic camera, (c) a home-made underwater camera and (d) an on-board LabSFLOC2 video microscopy equipment that used …

Impacts On Fast-Start Performance: How Do Group Size And Habitat Degradation Alter The Escape Behavior Of A Schooling Coral Reef Fish?, Monica D. Bacchus

All HCAS Student Capstones, Theses, and Dissertations

Escaping predation is essential for species survival, but prey must effectively match their response to the perceived threat imposed by a predator. Fish evaluate their surroundings using several sensory stimuli, including olfactory, visual, auditory, and mechanical cues. A range of taxa use the fast-start response to evade predators, including fishes, sharks, and larval amphibians. While the fast-start response (rapid bursts of swimming) is extensively studied in solitary fishes, the factors that mediate the collective escape response in schools of fish have historically been investigated far less. To address this knowledge gap, the collective escape behavior and individual escape performance of …

Preliminary Trials To Assess Bycatch Reduction Potential For Deep-Set Pelagic Longline Gear In The U.S. Atlantic Fishery, Sean T. Wilms

All HCAS Student Capstones, Theses, and Dissertations

The U.S. Atlantic pelagic longline fishery uses a shallow-set gear configuration to primarily target swordfish (Xiphias gladius) and yellowfin tuna (Thunnus albacares) at depths of around 75-100 m. However, the fishery has been the subject of several bycatch reduction regulations due to incidental catch and mortality of sea turtles, seabirds, marine mammals, and istiophorid billfishes. An alternative deep-set technique, used by the U.S. pelagic longline fishery based in Hawaii and several non-U.S. fleets, differs from the shallow-set pelagic longline gear by deploying a greater length of mainline per unit distance using a mechanical line shooter, resulting in a deeper catenary …

Increased Expression Of Interferon-Induced Transmembrane 3 (Ifitm3) In Stroke And Other Inflammatory Conditions In The Brain, Elisabeth Harmon, Andrea Doan, Jesus Bautista-Garrido, Joo Eun Jung, Sean P Marrelli, Gab Seok Kim

Faculty, Staff and Student Publications

Microglia, the resident innate immune cells of the brain, become more highly reactive with aging and diseased conditions. In collaboration with other cell types in brains, microglia can contribute both to worsened outcome following stroke or other neurodegenerative diseases and to the recovery process by changing their phenotype toward reparative microglia. Recently, IFITM3 (a member of the "interferon-inducible transmembrane" family) has been revealed as a molecular mediator between amyloid pathology and neuroinflammation. Expression of IFITM3 in glial cells, especially microglia following stroke, is not well described. Here, we present evidence that ischemic stroke causes an increase in IFITM3 expression along …

Longitudinal Expression Profiling Identifies A Poor Risk Subset Of Patients With Abc-Type Diffuse Large B Cell Lymphoma, F Bewicke-Copley, K Korfi, S Araf, Et Al

Peninsula Medical School

Despite the effectiveness of immuno-chemotherapy, 40% of patients with diffuse large B-cell lymphoma (DLBCL) experience relapse or refractory disease. Longitudinal studies have previously focused on the mutational landscape of relapse but fell short of providing a consistent relapse-specific genetic signature. In our study, we have focussed attention on the changes in gene expression profile accompanying DLBCL relapse using archival paired diagnostic/relapse specimens from 38 de novo DLBCL patients. Cell of origin remained stable from diagnosis to relapse in 80% of patients, with only a single patient showing COO switching from ABC to GCB. Analysis of the transcriptomic changes that occur …

A Novel Prognostic 7-Methylguanosine Signature Reflects Immune Microenvironment And Alternative Splicing In Glioma Based On Multi-Omics Analysis, Zihan Wang, Zhiwei Zhong, Zehua Jiang, Zepeng Chen, Yuequn Chen, Yimin Xu

Research outputs 2022 to 2026

Glioma is the most common type of central nervous system tumor with increasing incidence. 7-methylguanosine (m7G) is one of the diverse RNA modifications that is known to regulate RNA metabolism and its dysregulation was associated with various cancers. However, the expression pattern of m7G regulators and their roles in regulating tumor immune microenvironments (TIMEs) as well as alternative splicing events (ASEs) in glioma has not been reported. In this study, we showed that m7G regulators displayed a close correlation with each other and most of them were differentially expressed between normal and glioma tissues. Two m7G signatures were then constructed …

Random Field Modeling Of Multi-Trait Multi-Locus Association For Detecting Methylation Quantitative Trait Loci, Chen Lyu, Manyan Huang, Nianjun Liu, Zhongxue Chen, Philip J Lupo, Benjamin Tycko, John S Witte, Charlotte A Hobbs, Ming Li

Center for Medical Ethics and Health Policy Staff Publications

Motivation: CpG sites within the same genomic region often share similar methylation patterns and tend to be co-regulated by multiple genetic variants that may interact with one another.

Results: We propose a multi-trait methylation random field (multi-MRF) method to evaluate the joint association between a set of CpG sites and a set of genetic variants. The proposed method has several advantages. First, it is a multi-trait method that allows flexible correlation structures between neighboring CpG sites (e.g. distance-based correlation). Second, it is also a multi-locus method that integrates the effect of multiple common and rare genetic variants. Third, it models …

Human Mobility, Hospitality, And Tourism Industries: A Perspective On Catastrophes, Asif Hussain

Journal of Sustainability and Resilience

The coronavirus outbreak has resulted in a significant reduction in peoples’ movements, migration and trade at both local and global levels. Lockdowns and travel restrictions all over the world have led to a rapid retrenchment of the world’s hospitality and tourism sector. This is not new. Historically, catastrophes impacted human mobility. Drawing from the historical connections between catastrophes, especially health crises, this paper highlights the impacts of catastrophes on the hospitality and tourism industries. This research shows that the relationship between pandemic and tourism is turbulent, and it explores the implications of the current health crisis for the travel industry …

Nachos, A Cubesat-Based High-Resolution Uv-Visible Hyperspectral Imager For Remote Sensing Of Trace Gases: System Overview, Science Objectives, And Preliminary Results, Steven P. Love, Kirk W. Post, Logan A. Ott, Magdalena E. Dale, Claira L. Safi, Kerry G. Boyd, Hannah D. Mohr, Christian Ward, Michael Caffrey, James P. Theiler, Bernard R. Foy, Markus Hehlen, Charles Glen Peterson, Ryan Hemphill, James A. Wren, Arthur A. Guthrie, Nicholas A. Dallmann, Paul S. Stein, Aaron G. Meyer, Manvendra K. Dubey

Small Satellite Conference

The Nano-satellite Atmospheric Chemistry Hyperspectral Observation System (NACHOS) is a high-throughput (f/2.9), high spectral resolution (1.3 nm optical, 0.57 nm sampling) hyperspectral imager covering the 300-500 nm spectral region with 350 spectral bands. The combined 1.5U instrument payload and 1.5U spacecraft bus comprise a 3U CubeSat. Spectroscopically similar to NASA’s Ozone Monitoring Instrument (OMI), which provides wide-field coverage at ~20 km spatial resolution, NACHOS offers complementary targeted measurements at far higher spatial resolution of ~0.4 km/pixel from 500 km altitude over its 15 ̊ across-track field of view. NACHOS incorporates highly streamlined onboard gas-retrieval algorithms, alleviating the need to routinely …

Books Of Note

Appalachia

No abstract provided.

Why Walk? An Excerpt From The New Book Walking Distance, Robert E. Manning

Appalachia

No abstract provided.

Skiing On Copper And Coal: With Heavy Hearts, Five Friends Explore Land Scheduled For "Fracking" And Open-Pit Mining, John Gioia

Appalachia

No abstract provided.

Appalachia Summer/Fall 2013: Complete Issue

Appalachia

No abstract provided.

Analysis Of Primary And Secondary Ewing Sarcoma Outcomes, Andrew Ryan Kolodziej

Summer Experience 2022

No abstract provided.

Investigating Glucose Uptake Prognostic Effects On Pan Cancer Tcga By Metaflux, Kyle Tsai, Yuefan Huang, Ken Chen

Summer Experience 2022

No abstract provided.

Kmt2d Loss Promotes Head And Neck Squamous Cell Carcinoma Through Modulation Of Immune Microenvironment, Amanda Chiaha, Margarita Divenko, S. Carson Callahan, Emre Arslan, Kunal Rai

Summer Experience 2022

No abstract provided.

Research

Appalachia

No abstract provided.

The Night Life: Many Animals Are Becoming Increasingly Nocturnal In An Effort To Avoid Humans, Dawn Stover

Appalachia

No abstract provided.

The Wolf Called Or7: The First In California Since 1924, Jane Braxton Little

Appalachia

No abstract provided.

Cislunar Small Satellites And The Artemis Program, James Spann

Small Satellite Conference

No abstract provided.

Small Spacecraft Sample Return Mission Concept To Support Gateway And Lunar Science, Alan M. Cassell, Jeffrey D. Smith, Matthew M. Wittal, Randy D. Gordon, Jennifer G. Morgan

Small Satellite Conference

Sustaining long-term presence at the Moon will likely require innovative and cost-effective approaches for frequent and affordable payload return. NASA Ames Research Center and the Deep Space Logistics team at Kennedy Space Center (which manages the Gateway Logistics Services missions) have investigated the development of a small spacecraft-based sample return capability to complement the limited sample return capacity available with the early Orion missions. The goal is to demonstrate a cost-effective capability as part of an early Deep Space Logistics mission and provide up to 10 kg (~ 4 L volume) of scientific payload returned from the Gateway. The mission …

Books Of Note

Appalachia

No abstract provided.

Purifications Of Iraqi Petroleum Using Ceramic Ball Nano Cobalt Nickel Ferrite Filter, Huda Jabbar, Enas Muhi, Tahseen Hussien

Karbala International Journal of Modern Science

Iraqi petroleum, especially from the Al-Ahdab, has a big problem resulting from its high percentage of heavy metals. In this paper, heavy metals were reduced or removed from Iraqi petroleum using a Ceramic Ball Nano Cobalt Nickel Ferrite Filter (BCNF), synthesized by combining kaolin and palm frond in a 30% ratio with Co0.8Ni0.2Fe2O4 nanoparticles in a various ratios (5, 10, 15, and 20%). The sol-gel technique prepared Co0.8Ni0.2Fe2O4 nanoparticles. The structure and magnetic properties of the material are described using X-RD, FT-IR, and VSM techniques. In addition, the water ab-sorption ratio and apparent porosity were assessed. The results show that …

Studying The Physical And Biological Characteristics Of Denture Base Resin Pmma Reinforced With Zro2 And Tio2 Nanoparticles, Fatin A. Asim, Entessar H.A. Al-Mosaweb, Wafaa A. Hussain

Karbala International Journal of Modern Science

Polymethyl methacrylate (PMMA) suffers from poor mechanical properties that limit its application in the bio-medical field. In this study, PMMA was reinforced with zirconium dioxide (ZrO2) and titanium dioxide (TiO2) nanopar-ticles; subsequently, the hardness, porosity, biocompatibility, bacterial adhesion, and colonization of the reinforced PMMA with various oxide nanoparticles were characterized. The results of this study indicated that reinforced material inhibits bacterial growth and decreases bacterial adhesion by decreasing porosity and increasing PMMA hardness. Based on the findings, 3 wt% PMMA-ZrO2 and 3 wt% PMMA-ZrO2 -TiO2 composites significantly inhibited bacterial growth and adherence while maintaining hemolysis PT and INR and enhancing …

Skin Lesion Segmentation Based On U-Shaped Network, Muna Khalaf, Ban N. Dhannoon

Karbala International Journal of Modern Science

Skin lesion segmentation is an essential step toward accurate skin lesion diagnosis. The need to automate Skin lesion segmentation on the one hand, and the challenges it faces, on the other hand, have made it a growing area of research and focus. Automation of skin lesion segmentation helps reduce the effort and time needed for diagnosis and treatment and helps make better utilization of available data and shared experiences. The challenges faced by the automation of skin lesion segmentation can be broadly defined by (but not limited to); variations in texture, shape, and size for skin lesions and the low …

C60 Hydrofullerene Induced Autophagy And Ameliorated Gfap In H2o2 Treated Human Malignant Glioblastoma U-373 Cell Line, Aryan M. Faraj, Can A. Agca, Victor S. Nedzvetsky, Artem A. Tykhomyrov

Karbala International Journal of Modern Science

Glioblastoma is one of the most combative astrocytoma that is resistant to chemotherapy and radiotherapy. This resistance makes it very difficult to treat. However, researches have shown that nanoparticles especially C60 hydrofullerene have antioxidant and anticancer activity. The effect of C60 hydrofullerene in cancer has been extensively studied; however, the potential regulation of autophagy and modulation of the Glial Fibrillary Acidic Protein (GFAP) gene has not been addressed in glioblastomas. Glioblastoma U-373 cell was treated with 0.5 µM of C60 hydrofullerene and/or 1 mM of hydrogen peroxide (H2O2) for 24 hours. This study demonstrated that C60 hydrofullerene and H2O2 significantly …

Improving Prediction Of Arabic Fake News Using Fuzzy Logic And Modified Random Forest Model, Tahseen A. Wotaifi, Ban N. Dhannoon

Karbala International Journal of Modern Science

Throughout the last few years, the world is witnessing the so-called age of social media, as there is a complete dependence on these sites for following up on events and activities. The problem is that the misinformation or fake news is always released at the appropriate time, so this false news spreads quickly and takes a very wide resonance. Although several studies are performed to determine English fake news, the identification of Arabic misinformation remains underdeveloped. This study aims to build an improved learning model for detecting fake news in the Arabic language. Unlike previous studies that depended on analyzing …

Synthesized Zinc Nanoparticles Via Pulsed Laser Ablation: Characterization And Antibacterial Activity, Sahar Naji Rashid, Kadhim A. Aadim, Awatif Sabir Jasim, Arshad Mahdi Hamad

Karbala International Journal of Modern Science

The pulsed laser ablation of a metallic target in the liquid (PLAL) is a modern and good method for creating a variety of nanomaterials that have piqued the interest of researchers in the last decade. It is used in this work to prepare zinc na-noparticles and zinc oxide nanoparticles (ZnPNs and ZnO NPs) using Nd: YAG laser with the two wavelengths (532 nm) and (355 nm) using the energies (600 mJ) and (500 mJ) respectively, and the number of the pulse (500, 600, 700, 800, and 900 Pulses); for each wavelength used in this work. The properties of the prepared …

A Successful Elimination Of Indonesian Sars-Cov-2 Variants And Airborne Transmission Prevention By Cold Plasma In Fighting Covid-19 Pandemic: A Preliminary Study, Muhammad Nur, Chairul A. Nidom, Setyarina Indrasari, Arif N. M. Ansori, Mohamad Y. Alamudi, Astria N. Nidom, Sumariyah Sumariyah, Eva Sasmita, Eko Yulianto, Andi W. Kinandana, Anwar Usman, Muhammad K. J. Kusala, Irine Normalina, Reviany V. Nidom

Karbala International Journal of Modern Science

Global infection and mortality rates have soared to millions due to SARS-CoV-2 human-to-human transmission from via droplets which then declared as pandemic. This study examined the created cold plasma equipment (CPE) effectiveness in reducing COVID-19 transmission in a confined space. CPE sucked air using a fan in a test chamber then pushed it into a cold plasma reactor. The results indicated that it was able to terminate all SARS-CoV-2 variants along with bacteria and fungi indoors by keeping it turned on for 30 minutes’ minimum. CPE was proven as safe and effective to hinder virus transmission with the acceptable ozone …

The Phenomena Of Dimming And Its Effect On The Agricultural Production In Iraq, Dr. Ammar Mohammed Zakariya, Dr. Hatem Hamoodi Hassan

Midad AL-Adab Refereed Quarterly Journal

In the current time there is an increase in the global interest concerning the atmospheric changes in the world, threatening for a vanishing to the botanical and biological environments from the surface of the globe. The increase in pollution phenomena due to the development and the exaggeration in utilizing the natural resources and using methods and agricultural techniques both botanical and animal, show an environmental imbalance in increasing CO2 in air and an increase in the non responsible human activities resulted an increase in the desertification area and the shortage in the rain quantity and the increase of the hidden …