Digital Commons Network^™

The Efficacy And Safety Of Adding Olanzapine To Triple Drugs Regimen To Prevent Chemotherapy-Induced Nausea And Vomiting: A Systematic Review And Meta-Analysis Of Rcts, Sharanabasayyaswamy B. Hiremath, Srinivas L. Devendrappa

Pharmacology and Clinical Pharmacy Research

Chemotherapy-induced nausea and vomiting (CINV) is a complication of highly emetogenic chemotherapy (HEC) agents. The present meta-analysis was conducted to quantify and analyze the efficacy and safety of adding olanzapine to a Neurokinin Receptor Antagonist (NKRA) based triple-drug regimen in preventing HEC-induced CINV. Electronic database searches in PUBMED and Cochrane library was conducted using MeSH search terms “olanzapine” and “chemotherapy-induced nausea and vomiting.” Randomized or cross-over trials comparing the efficacy of “olanzapine + NKRA based triple-drug regimen” vs. “placebo + NKRA based triple-drug regimen” in patients of age > 18 years with any malignancy receiving HEC were considered under inclusion criteria. …

Perceptual Analysis Of Distance Sampling And Transmittance Estimation Techniques In Biomedical Volume Visualization, Raazia Sosan, Muhammad Mobeen Movania, Shama Siddiqui

Turkish Journal of Electrical Engineering and Computer Sciences

In volumetric path tracer, distance sampling and transmittance estimation techniques play a vital role in producing high-quality final rendered images. Previously, these techniques were implemented for production volume rendering, and were analyzed for faster convergence. In this article, we have augmented additional transmittance estimators including ratio tracking, residual ratio tracking and unbiased ray marcher in a GPU-based volumetric path tracer (Exposure Render) for biomedical datasets. We have also analyzed distance sampling methods and transmittance estimators perceptually using CIEDE2000 and Structural Similarity Index (SSIM). It was found that ratio and residual ratio tracking estimators performed close to each other and were …

Environmental Justice For Food System Workers: Heat-Illness Prevention Standards As One Step Toward Just Transition, Sarah A. Matsumoto

Publications

No abstract provided.

Total Wellness Of Turkish International Students: Perceptions And Inherent Growth Tendencies, Mehmet Avci, Romulo E. Montilla

Journal of Comparative & International Higher Education

Research on the international students primarily focuses on adjustment and acculturation issues rather than building and maintaining the wellness of specific cultural groups of international students. This study used basic psychological needs involved in self-determination theory to investigate the relationship between autonomy, competence, and relatedness needs, self-determined way of functioning, and wellness of Turkish international students in the U.S. Data was collected before Covid-19 pandemic using a self-administered survey from 179 (71 females) Turkish international students with a mean age of 29.7 years. The results indicated that the perceived total wellness of Turkish international students was slightly low. The results …

The Covid-19 Pandemic And Disruptions To Essential Health Services In Kenya: A Retrospective Time-Series Analysis, Helen Kiarie, Marleen Temmerman, Mutono Nyamai, Nzisa Liku, Wangari Thuo, Violet Oramisi, Lilly Nyaga, Janette Karimi, Phidelis Wamalwa, Gladwell Gatheca

Obstetrics and Gynaecology, East Africa

Background: Public health emergencies can disrupt the provision of and access to essential health-care services, exacerbating health crises. We aimed to assess the effect of the COVID-19 pandemic on essential health-care services in Kenya.

Methods: Using county-level data routinely collected from the health information system from health facilities across the country, we used a robust mixed-effect model to examine changes in 17 indicators of essential health services across four periods: the pre-pandemic period (from January, 2018 to February, 2020), two pandemic periods (from March to November 2020, and February to October, 2021), and the period during the COVID-19-associated health-care workers’ …

Symptoms Of Maternal Psychological Distress During Pregnancy: Sex-Specific Effects For Neonatal Morbidity, Sandra J. Weiss, Joseph Musana

Obstetrics and Gynaecology, East Africa

Objectives: Maternal psychological distress during pregnancy has been associated with preterm birth. However, little is known about the relationship of a woman’s psychological symptoms during pregnancy to the infant’s morbidity at birth or any differential effects of these symptoms on female vs. male fetuses. Our research aims addressed these gaps.

Methods: A total of 186 women were enrolled between 24 and 34 weeks gestation when demographic information was acquired and they completed the Brief Symptom Inventory to measure psychological distress. Data on gestational age at birth, fetal sex, and neonatal morbidity was extracted from the medical record. To control for …

8th Circuit Panel Affirms Preliminary Injunction Against Arkansas Law Banning Gender Transition Treatment For Minors, Arthur S. Leonard

Other Publications

No abstract provided.

Alternative Modes Of Entry And Unexpected Events In Franchising, Alexander Rosado-Serrano, Antonio Navarro-García

Journal of Global Business Insights

Store-in-store franchising or corner franchising is the application of a franchise format within another business, such as big box retailers, supermarkets, and gas stations; and pop-up stores are temporary store formats opened in shopping malls or other venues for a short period. Despite the regular application of these strategies by franchisers, the academic literature on store-in-store franchising and pop-up stores is relatively limited. There is a particular need after the COVID-19 outbreak to construct new lenses through which to explore how these modes of entry adapt to the new environment of business interruptions and border closures. Motivated by this research …

Hic2 Controls Developmental Hemoglobin Switching By Repressing Bcl11a Transcription, Peng Huang, Scott A Peslak, Ren Ren, Eugene Khandros, Kunhua Qin, Cheryl A Keller, Belinda Giardine, Henry W Bell, Xianjiang Lan, Malini Sharma, John R Horton, Osheiza Abdulmalik, Stella T Chou, Junwei Shi, Merlin Crossley, Ross C Hardison, Xiaodong Cheng, Gerd A Blobel

Faculty, Staff and Student Publications

The fetal-to-adult switch in hemoglobin production is a model of developmental gene control with relevance to the treatment of hemoglobinopathies. The expression of transcription factor BCL11A, which represses fetal β-type globin (HBG) genes in adult erythroid cells, is predominantly controlled at the transcriptional level but the underlying mechanism is unclear. We identify HIC2 as a repressor of BCL11A transcription. HIC2 and BCL11A are reciprocally expressed during development. Forced expression of HIC2 in adult erythroid cells inhibits BCL11A transcription and induces HBG expression. HIC2 binds to erythroid BCL11A enhancers to reduce chromatin accessibility and binding of transcription factor GATA1, …

Multidimensional Single-Cell Analysis Identifies A Role For Cd2-Cd58 Interactions In Clinical Antitumor T Cell Responses, Gabrielle Romain, Paolo Strati, Ali Rezvan, Mohsen Fathi, Irfan N Bandey, Jay R T Adolacion, Darren Heeke, Ivan Liadi, Mario L Marques-Piubelli, Luisa M Solis, Ankit Mahendra, Francisco Vega, Laurence Jn Cooper, Harjeet Singh, Mike Mattie, Adrian Bot, Sattva S Neelapu, Navin Varadarajan

Faculty, Staff and Student Publications

The in vivo persistence of adoptively transferred T cells is predictive of antitumor response. Identifying functional properties of infused T cells that lead to in vivo persistence and tumor eradication has remained elusive. We profiled CD19-specific chimeric antigen receptor (CAR) T cells as the infusion products used to treat large B cell lymphomas using high-throughput single-cell technologies based on time-lapse imaging microscopy in nanowell grids (TIMING), which integrates killing, cytokine secretion, and transcriptional profiling. Our results show that the directional migration of CD19-specific CAR T cells is correlated with multifunctionality. We showed that CD2 on T cells is associated with …

Pharmacokinetic Evaluation Of Intravenous Vitamin C: A Classic Pharmacokinetic Study., Ping Chen, Greg Reed, Joyce Jiang, Yaohui Wang, Jean Sunega, Ruochen Dong, Yan Ma, Anna E. Esparham, Ryan Ferrell, Mark Levine, Jeanne Drisko, Qi Chen

Manuscripts, Articles, Book Chapters and Other Papers

Purpose: Intravenous vitamin C (IVC) is used in a variety of disorders with limited supporting pharmacokinetic data. Herein we report a pharmacokinetic study in healthy volunteers and cancer participants with IVC doses in the range of 1-100 g.

Methods: A pharmacokinetic study was conducted in 21 healthy volunteers and 12 oncology participants. Healthy participants received IVC infusions of 1-100 g; oncology participants received IVC infusions of 25-100 g. Serial blood and complete urine samples were collected pre-infusion and for 24 h post-infusion. Pharmacokinetic parameters were computed using noncompartmental methods. Adverse events were monitored during the study.

Results: In both cohorts, …

Integrated Imaging And Molecular Analysis To Decipher Tumor Microenvironment In The Era Of Immunotherapy, Jia Wu, Aaron T Mayer, Ruijiang Li

Faculty, Staff and Student Publications

Radiological imaging is an integral component of cancer care, including diagnosis, staging, and treatment response monitoring. It contains rich information about tumor phenotypes that are governed not only by cancer cellintrinsic biological processes but also by the tumor microenvironment, such as the composition and function of tumor-infiltrating immune cells. By analyzing the radiological scans using a quantitative radiomics approach, robust relations between specific imaging and molecular phenotypes can be established. Indeed, a number of studies have demonstrated the feasibility of radiogenomics for predicting intrinsic molecular subtypes and gene expression signatures in breast cancer based on MRI. In parallel, promising results …

Chth 355.01: Theory And Practice Of Community Health Education, Ashley Glass

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Csd 222.01: Introduction To Audiology, Kevin D. Duffy

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Pubh 155.01: Reimagining Global Health - Biosocial Perspectives, Gilbert A. Quintero

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Pubh 615.50: Infectious Disease Epidemiology And Control, Sophia Raff Newcomer, Erin Landguth

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Slp 591.52: Voice & Resonance Disorders, Jane E. Reynolds

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Psyx 120.50: Introduction To Research Methods – Online, Caitlin A. Martin-Wagar

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Psyx 233.50: Fundamentals Of Psychology Of Aging - Online, Hannah G. Hall

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Psyx 250n.01: Fundamentals Of Biological Psychology, Amber L. Thatcher

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Psyx 330.01: Child Development, Rachel L. Severson

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Psyx 352.01: Comparative Psychology, D. Allen Szalda-Petree

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Psyx 385.01: Psychology Of Personality - Methodology, Theories, & Application, Duncan G. Campbell

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Psyx 571.01: Advanced Physiological Psychology, D. Stuart Hall

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Musi 112a.02: Choir - Chamber Chorale, Coreen S. Duffy

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Musi 312.02: Choir Iii - Chamber Chorale, Coreen S. Duffy

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Slp 560.00: Language Assessment And Intervention For School-Age Children And Adolescents, Ginger G. Collins

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Nutr 221n.02: Basic Human Nutrition, Laura Granlund

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Bios 532.01: Fundamentals Of Ecosystem Ecology, Cory C. Cleveland

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Fors 330.00: Forest Ecology, Tyler J. Hoecker

University of Montana Course Syllabi, 2021-2025

No abstract provided.