Digital Commons Network^™

Chemical Disease Relation Extraction Through The Combination Of Multiple Mention Levels: Relscan+, Stanley Chika Onye, Nazi̇fe Di̇mi̇li̇ler, Ari̇f Akkeleş

Turkish Journal of Electrical Engineering and Computer Sciences

Chemical-induced disease (CID) relation extraction has been pivotal in the understanding of biological processes. A CID relation between a chemical and disease entity may be extracted either from a single sentence or from two or more adjacent sentences. We use `intrasentence level' to refer to the mention of the desired entities in the same sentence and `intersentence level? to refer to the mention of these entities in two or more adjacent sentences. This study proposes a three-phase architecture for extracting CID relations from biomedical literature by considering both sentence levels and additionally the combination of these two sentence levels which …

Design And Implementation Of A Low Cost And Portable Tactile Stimulator, Coşkun Kazma, Vecdi̇ Emre Levent, Merve Çardak, Ni̇zametti̇n Aydin

Turkish Journal of Electrical Engineering and Computer Sciences

When central nervous system has a problem, somatic area I and II respond to stimulation differently. Therefore, it is possible to identify some of the central nervous diseases when somatosensory on the fingertip is stimulated and responses are recorded and analyzed. We designed a system to stimulate the mechanoreceptors on fingertips. It is composed of a mechanical system for fingertip stimulation, an embedded controller, a control computer, and a software to control overall operation. During test, mechanoreceptors are stimulated according to the test protocols. Individuals' answers are recorded to be evaluated by the developed software. In this study, several design …

Rates Of Future Climate Change In The Gulf Of Mexico And The Caribbean Sea: Implications For Coral Reef Ecosystems, A. E. Lawman, S. G. Dee, K. L. Delong, A. M.S. Correa

Faculty Publications

Rising temperatures and ocean acidification due to anthropogenic climate change pose ominous threats to coral reef ecosystems in the Gulf of Mexico (GoM) and the western Caribbean Sea. Unfortunately, the once structurally complex coral reefs in the GoM and Caribbean have dramatically declined since the 1970s; relatively few coral reefs still exhibit a mean live coral cover of >10%. Additional work is needed to characterize future climate stressors on coral reefs in the GoM and the Caribbean Sea. Here, we use climate model simulations spanning the period of 2015–2100 to partition and assess the individual impacts of climate stressors on …

Dermatologic Manifestations Of Rheumatic Disease: Cutaneous Manifestations Of Sarcoidosis, Sarah Shapiro, Sindhuja Koppu, Mavra Masood, Beth Rubinstein, Huzaefah Syed

Open Textbooks and Course Materials

This OER is a part of the Dermatologic Manifestations of Rheumatic Disease project, which provides overviews of the identification, diagnosis, and workup for different rheumatologic diseases, with a focus on providing examples from persons of color (POC). This work seeks to fill gaps and exclusionary practices in medical education practices and resources and diagnostic frameworks in regards to skin of color. This lack of representation bodes significant repercussions on the ability of future physicians to deliver equitable care for an increasingly diverse US population. Each module consists of a similar Powerpoint format, which includes key objectives, hypothetical disease cases, an …

Menstrual Irregularities Following Covid-19 Vaccination: A Global Cross-Sectional Survey, Azza Sarfraz, Zouina Sarfraz, Muzna Sarfraz, Zainab Nadeem, Miguel Felix, Ivan Cherrez-Ojeda

Department of Paediatrics and Child Health

Introduction: The coronavirus disease 2019 (COVID-19) vaccination generates protective immunity against SARS-CoV-2 infection. There is no clear evidence of COVID-19 vaccine-induced menstrual irregularities.
Objective: To identify potential menstrual irregularities following COVID-19 vaccine among females.
Methods: A worldwide cross-sectional survey study was conducted from June 10, 2021, to July 10, 2021 using online mediums. The survey consisted of 15 questions divided into baseline characteristics, vaccination status and dosage, menstruation and relate factors, and thoughts and knowledge about menstrual irregularities. Non-probability convenience sampling method was used including 510 responses. The results were tabulated, with bivariate analysis and chi-square test results. The sensitivity …

Natural Shoreline Infrastructure In Humboldt Bay For Intertidal Coastal Marsh Restoration And Transportation Corridor Protection: 50% Design Report, Ghd, Northern Hydrology & Engineering, Conor Shea

Local Reports and Publications

This report evaluates the feasibility of a project to develop natural shoreline infrastructure, also known as nature-based adaptation strategies or nature-based solutions, along a vulnerable segment of Humboldt Bay shoreline adjacent to the Highway 101 transportation corridor between Eureka and Arcata.

Critical Social Foundations Of Education: Advancing Human Rights And Transformative Justice Education In Teacher Preparation, Magnus O. Bassey

Publications and Research

No abstract provided.

Ba-Ba-Bachman’S: A Note On Song Production In Juvenile Bachman’S Sparrows (Peucaea Aestivalis), Hans Gonzembach, Heather Wolverton, Rindy Anderson

Florida Field Naturalist

No abstract provided.

Inconceivable Families, Malinda L. Seymore

Faculty Scholarship

Basic biology tells us that each child has no more than two biological parents, one who supplies the egg and one who supplies the sperm. Adoption law in this country has generally followed biology, insisting only two parents be legally recognized for each child. Thus, every adoption begins with loss. Before a child can be adopted, that child must first be cut off from their family of birth, rendering the equation of adoption one of subtraction, not addition. This Article examines the biological model of adoption that insists on mimicking the nuclear family—erasing one set of parents and replacing them …

Parading The Horribles: The Risks Of Expanding Religious Exemptions, Law, Rights, And Religion Project

Center for Gender & Sexuality Law

People of faith now have a constitutional right to practice their religion—even when doing so conflicts with a government law or policy — that is more rigorously protected than nearly any other right. Some states have passed bills that provide an even broader right to such “religious exemptions” from the law than provided under the U.S. Constitution. Other religious exemption bills have been introduced and await consideration.

Understanding "Death": Creating Student Opportunities For Meaningful Emotional Expression In The Science Classroom, Zachary Schafer, Lawrence C. Scharmann

Department of Teaching, Learning, and Teacher Education: Faculty Publications

Understanding death as natural and integral to life cycles has been considered crucial and relevant in science teaching. The concept of death not only defines the physical end of life but also the end of a cycle and the beginnings of transformation. Adopting a broader definition of death thus empowers educators to directly address the affect and emotion that occurs for all students.

Regulation Weakness And Lack Of Public Awareness Has Impeded The Implementation Of Environmental Policies In Saudi Arabia, Nada Gurmalla Algamdy

Dissertations & Theses

This research aimed to substantially illustrate that the weakness of environmental regulations and lack of public participation in urban planning alongside poor public awareness in Saudi Arabia has inhibited the implementation of environmental policies across this region. To study these issues, this research compared the Kingdom of Saudi Arabia (“KSA”) to the United States (“US”) building on numerous studies to illustrate how the identified weaknesses correlate with weak or ineffective environmental policies. It is well known that it would be better to use a European country “because it's known that the EU has tough environmental measures" as a model for …

Updates On The Hidradenitis Suppurativa From The Usa, Iltefat H. Hamzavi

Dermatology Meeting Abstracts

Background: There has been so much progress in hidradenitis suppurativa across the world.

Objectives: The focus of this talk will be the American contributions to this effort but very few of these efforts involve any one nation.

Methods/Results: Updates from American institutions will be provided with a focus on immunology, the microbiome, genetics, outcome measures, antibiotics, biologics, lasers, surgery multidisciplinary clinics, big data and support groups. Updates about the efforts of the American HS foundation will also be discussed.

Conclusion: There is much to celebrate about the advances in HS across the world. North America and the United States are …

33354 Efficacy Of Apremilast In Patients With Mild To Moderate Psoriasis Assessed By The Physician Global Assessment And Body Surface Area Composite Tool: Post Hoc Analysis From Advance, Linda F. Stein Gold, Kim Papp, David Pariser, Howard Sofen, Mindy Chen, Sue Cheng, Hernan Picard, Yuri Klyachkin, Lawrence Green

Dermatology Meeting Abstracts

Background: In ADVANCE (NCT03721172), apremilast 30 mg BID (APR) demonstrated significantly greater sPGA response vs. PBO at Week 16 (22% vs. 4%; P <.0001) in patients with mild-to-moderate psoriasis. The Physician Global Assessment and Body Surface Area Composite Tool (PGA × BSA) is a simple, sensitive measure of psoriasis severity for patients with BSA<10%. We performed a post hoc analysis of the efficacy results from ADVANCE using the PGA×BSA.

Methods: This current post hoc analysis included all randomized patients. Missing data were imputed by multiple imputation. PGAxBSA-50/75/90 was 50%, 75% and 90% improvement in PGAxBSA from baseline.

Results: Of 595 randomized patients (APR: 297; PBO: 298), baseline characteristics were similar for mean BSA (APR: 6.4; PBO: 6.3), sPGA score 2 (APR 31%; PBO: 31%), sPGA score 3 (APR: 69%; PBO: 70%), and mean PGA×BSA (APR: 17.6; PBO: 17.5). At Week 16, significantly more patients achieved PGAxBSA-50/75/90 …

35360 Recalcitrant Pediatric Bullous Erythema Multiforme Responsive To Oral Tofacitinib, Sasank Konda, Nayha Shetty, Jesse Y. Liu

Dermatology Meeting Abstracts

Patient history and physical: A 25-year-old African American female was admitted for painful oral erosions and widespread blistering lesions on the trunk and extremities which had been waxing and waning since age 12 years old. Disease flares requiring hospitalization had been continuing to occur multiple times annually in spite of numerous systemic immunosuppressive agents including chronic corticosteroids (resulting in Cushingoid features and insulin-dependent diabetes) in combination with cyclosporine, dapsone, tacrolimus, anakinra, rituximab, adalimumab, apremilast, mycophenolate mofetil, and intravenous immunoglobulin (IVIG) at various times. Adjunctive therapies including acyclovir and leuprolide had also proven ineffective. Physical examination revealed well-defined, targetoid macules with …

Towards An Operational Irrigation Management System For Sweden With A Water–Food–Energy Nexus Perspective, P. E. Campana, P. Lastanao, S. Zainali, J. Zhang, T. Landelius, F. Melton

AES Faculty Publications and Presentations

The 2018 drought in Sweden prompted questions about climate-adaptation and -mitigation measures – especially in the agricultural sector, which suffered the most. This study applies a water–food–energy nexus modelling framework to evaluate drought impacts on irrigation and agriculture in Sweden using 2018 and 2019 as case studies. A previous water–food–energy nexus model was updated to facilitate an investigation of the benefits of data-driven irrigation scheduling as compared to existing irrigation guidelines. Moreover, the benefits of assimilating earth observation data in the crop model have been explored. The assimilation of leaf area index data from the Copernicus Global Land Service improves …

Law, Labour And Landscape In A Just Transition, Adrian A. Smith, Dayna Nadine Scott

Articles & Book Chapters

Taking conflicts over new solar energy projects on the agricultural landscape in the global North as its backdrop, the chapter demonstrates how work and labour (including that performed in the North by workers from the global South) are erased both by the opponents and the proponents of such projects. The erasure is consistent with prevailing ways of knowing the human-environment nexus, shaped by an underlying political economy derivative of how international law has constructed and maintained the foundational liberal mythology that separates labour from land. Grounded in our commitment to pursuing a ‘just transition’ to decarbonisation – that is to …

Potential Impacts Of Hemlock Woolly Adelgid Infestation On Forest Overstory And Avian Assemblages In West Michigan, Usa, Nathaniel Sq Wagner

Masters Theses

Invasive species threaten the health and resiliency of native ecosystems wherever they are found. The damage caused by invasive species often leads to a cascade that degrades the ecosystem as a whole. In eastern North America, the invasive insect, hemlock woolly adelgid (Adelges tsugae; HWA), threatens the continued existence of eastern hemlock (Tsuga canadensis) and the species that are associated with it. Often considered a foundation species, eastern hemlock influences the structure and composition of eastern forests by lowering soil temperature, subsequently raising soil moisture content. In the absence of hemlock, many forests become dominated by …

Figuring Embedded Librarianship: An Analysis Of The Embedded Journalist Metaphor In The Professional Discourse, Rachel L. Edford

Faculty Scholarship and Creative Works

In the wake of the COVID pandemic, many academic libraries sought virtual instruction options, like the embedded librarian model, bringing renewed interest to the topic. Debates defining embedded librarianship are plentiful and varied, but a review of the professional literature reveals a commonly used metaphor comparing embedded librarians to embedded journalists. This paper analyses the prevalence of that metaphor in the professional discourse through the lens of cognitive metaphor theory (CMT) to reveal the semantic and pragmatic implications of its use. CMT highlights the power of figurative language to reflect and define professional identities. The metaphor’s militaristic rhetoric counters negative …

Shore-Based Recreational Fishing In The Perth Metropolitan Area: 2022, Alissa Tate, Lucy Rudd, Claire B. Smallwood

Fisheries Research Reports

Recreational fishing is a popular activity in Western Australia (WA), occurring throughout the state from boats, and from a variety of natural and man-made structures along the shore. Ongoing monitoring of the shore-based recreational fishery is essential to assist with resource allocation, management evaluation and stock assessments for nearshore species. Especially for species such as Australian Herring and Southern Garfish which had management changes including a reduction in bag limit from 30 to 12 in 2015 and closure of Perth Metropolitan waters in 2017, respectively. An on-site roving creel survey to collect effort and catch data from shore fishers has …

Implementing Github Actions Continuous Integration To Reduce Error Rates In Ecological Data Collection, Albert Y. Kim, Valentine Herrmann, Ross Barreto, Brianna Calkins, Erika Gonzalez-Akre, Daniel J. Johnson, Jennifer A. Jordan, Lukas Magee, Ian R. Mcgregor, Nicolle Montero, Karl Novak, Teagan Rogers, Jessica Shue, Kristina J. Anderson-Teixeira

Statistical and Data Sciences: Faculty Publications

Accurate field data are essential to understanding ecological systems and forecasting their responses to global change. Yet, data collection errors are common, and data analysis often lags far enough behind its collection that many errors can no longer be corrected, nor can anomalous observations be revisited. Needed is a system in which data quality assurance and control (QA/QC), along with the production of basic data summaries, can be automated immediately following data collection.

Here, we implement and test a system to satisfy these needs. For two annual tree mortality censuses and a dendrometer band survey at two forest research sites, …

“Lock Us In A Room Together”—Local Students’ Suggestions For Improving Socialization With International Students, Vander Tavares

Journal of Comparative & International Higher Education

In Canada, research has examined international-local student interaction by focusing on international students’ perceptions and experiences. As such, the perspectives of local students toward socialization with international students remain less explored. Designed as a survey-based case study with 17 local students at a university in Ontario, this study sought to understand the perspectives of local students on how to improve socialization between the two groups. Additionally, this study investigated how local students conceptualized their experiences of multiculturalism and multilingualism at their university, considering the importance of diversity for the development of intercultural knowledge and intercultural relationships. Findings suggest that local …

Usp7 Substrates Identified By Proteomics Analysis Reveal The Specificity Of Usp7, Litong Nie, Chao Wang, Xiaoguang Liu, Hongqi Teng, Siting Li, Min Huang, Xu Feng, Guangsheng Pei, Qinglei Hang, Zhongming Zhao, Boyi Gan, Li Ma, Junjie Chen

Faculty, Staff and Student Publications

Deubiquitylating enzymes (DUBs) remove ubiquitin chains from proteins and regulate protein stability and function. USP7 is one of the most extensively studied DUBs, since USP7 has several well-known substrates important for cancer progression, such as MDM2, N-MYC, and PTEN. Thus, USP7 is a promising drug target. However, systematic identification of USP7 substrates has not yet been performed. In this study, we carried out proteome profiling with label-free quantification in control and single/double-KO cells of

655mo Quality Of Life In Patients With P16+ Oropharyngeal Cancer Receiving Accelerated Radiotherapy (Rt) With Either Cisplatin Or Cetuximab In Nrg/Rtog 1016, J. Ringash, L. Demora, M. L. Gillison, D. J. Adelstein, P. Harari, E. M. Sturgis, E. M. Basch, S. A. Koyfman, G. A. Krempl, D. M. Blakaj, J. E. Bates, T. Galloway, C. U. Jones, B. M. Beadle, P Torres-Saavedra, Q. T. Le, Benjamin Movsas

Radiation Oncology Meeting Abstracts

Background: This phase 3 randomized non-inferiority de-escalation trial compared cetuximab (cetux) vs cisplatin (cis), concurrent with accelerated RT 70 Gy/6 weeks, in p16+ oropharyngeal cancer (OPC). Quality of life (QOL) was an important secondary endpoint.

Methods: EORTC QLQ-C30/HN35 was completed at baseline, end of treatment, 3, 6, and 12 months post. The substudy aimed for 400 eligible patients. We report completion rates and compare by arm for change from baseline in each domain (0.05 two-sided alpha and MID of 10 points) using linear mixed models.

Results: Consent was 91% (381/419 offered substudy); 6 protocol deviations excluded (n=375). No significant differences …

Community-Powered Urban Stream Restoration: A Vision For Sustainable And Resilient Urban Ecosystems, Mateo Scoggins, Derek B. Booth, Tim Fletcher, Megan Fork, Ana Gonzalez, Rebecca L. Hale, Robert J. Hawley, Allison H. Roy, Erika E. Bilger, Nick Bond, Matthew James Burns, Kristina G. Hopkins, Kate H. Macneale, Eugenia Marti, Kyle S. Mckay, Martin W. Neale, Michael J. Paul, Blanca Rios-Touma, Kathryn L. Russell, Robert F. Smith, Staryn Wagner, Seth Wenger

Biology Faculty Publications

Urban streams can provide amenities to people living in cities, but those benefits are reduced when streams become degraded, potentially even causing harm (disease, toxic compounds, etc.). Governments and institutions invest resources to improve the values and services provided by urban streams; however, the conception, development, and implementation of such projects may not include meaningful involvement of community members and other stakeholders. Consequently, project objectives may be misaligned with community desires and needs, and projects may fail to achieve their goals. In February 2020, the 5(th) Symposium on Urbanization and Stream Ecology, an interdisciplinary meeting held every 3 to 5 …

Breast Cancer In Geriatric Patients: Current Landscape And Future Prospects, Hikmat Abdel-Razeq, Fawzi Abu Rous, Fawzi Abuhijla, Nayef H. Abdel-Razeq, Sarah Edaily

Hematology/Oncology Articles

Breast cancer is the most common cancer diagnosed among women worldwide and more than half are diagnosed above the age of 60 years. Life expectancy is increasing and the number of breast cancer cases diagnosed among older women are expected to increase. Undertreatment, mostly due to unjustifiable fears of advanced-age and associated comorbidities, is commonly practiced in this group of patients who are under-represented in clinical trials and their management is not properly addressed in clinical practice guidelines. With modern surgery and anesthesia, breast surgeries are considered safe and is usually associated with very low complication rates, regardless of extent …

Epigenetic Influences Of Mobile Genetic Elements On Ciliate Genome Architecture And Evolution, Caitlin M. Timmons, Shahed U.A. Shazib, Laura A. Katz

Biological Sciences: Faculty Publications

Mobile genetic elements (MGEs) are transient genetic material that can move either within a single organism's genome or between individuals or species. While historically considered “junk” DNA (i.e., deleterious or at best neutral), more recent studies reveal the potential adaptive advantages MGEs provide in lineages across the tree of life. Ciliates, a group of single-celled microbial eukaryotes characterized by nuclear dimorphism, exemplify how epigenetic influences from MGEs shape genome architecture and patterns of molecular evolution. Ciliate nuclear dimorphism may have evolved as a response to transposon invasion and ciliates have since co-opted transposons to carry out programmed DNA deletion. Another …

Taxon-Rich Transcriptomics Supports Higher-Level Phylogeny And Major Evolutionary Trends In Foraminifera, Roberto Sierra, Florian Mauffrey, Joana Cruz, Maria Holzmann, Andrew J. Gooday, Xyrus Maurer-Alcalá, Rabindra Thakur, Mattia Greco, Agnes K.M. Weiner, Laura A. Katz, Jan Pawlowski

Biological Sciences: Faculty Publications

Foraminifera, classified in the supergroup Rhizaria, are a common and highly diverse group of mainly marine protists. Despite their evolutionary and ecological importance, only limited genomic data (one partial genome and nine transcriptomic datasets) have been published for this group. Foraminiferal molecular phylogeny is largely based on 18S rRNA gene sequence analysis. However, due to highly variable evolutionary rates of substitution in ribosomal genes plus the existence of intragenomic variation at this locus, the relationships between and within foraminiferal classes remain uncertain. We analyze transcriptomic data from 28 species, adding 19 new species to the previously published dataset, including members …

Covid-19 Mindfulness Toolkit: A 4-Week Course For Adult Working Professionals, Ilene Gregorian

Mindfulness Studies Theses

The COVID-19 pandemic is unprecedented in terms of size and scale, and has impacted virtually every facet of life across the world over the past two and a half years. For adult working professionals, it has presented enormous challenges including work-from-home mandates, video conferencing, homeschooling, unplanned childcare, financial instability, and prolonged uncertainty leading to increased fear, stress, anxiety, and loneliness. Other work on this topic reports that even a short program in mindfulness can help adult working professionals counteract the negative effects of chronic stress and trauma. This study argues that my proposed program with four specific mindfulness practices entitled …

Yoga And Reiki As Self-Care Interventions For Professional Nurses: A Weekend Retreat, Diane Friel

Mindfulness Studies Theses

Nurses provide compassionate care to their patients and often fail to turn that compassion inwards. Nurses are experiencing unprecedented levels of stress in the workplace related to the COVID-19 pandemic and research shows that workplace stress has a negative impact on both nurses and the patients they care for. The wellness of the nursing force is a public health priority. This paper describes the workplace challenges facing nurses today, and the associated impact on nurses and patients is supported with research. Research is offered supporting self-care and self-compassion as vital components to wellness, enhanced emotional resilience, and prevention of burnout …