Digital Commons Network^™

Social Control Through The Reconstitution Of Man, Leroy L. Lamborn

Florida Law Review

No abstract provided.

The Indispensable Role Of Independent Ethical Judgment, Robert C. L. Moffat

Florida Law Review

No abstract provided.

The New Biology And The Law, Ernest M. Jones, Rene Dubos, Warren E. Burger, Emil Mantini, Samuel P. Martin, Marcus L. Plant

Florida Law Review

No abstract provided.

Statistical Morality, Law And Tomorrow's World, Joseph W. Little

Florida Law Review

No abstract provided.

Developing A Public Justice Perspective, Lexi Schnaser

Student Work

"I tried to balance that question of 'What would Jesus do?' with practical policy answers."

Posting about promoting human flourishing from In All Things - an online journal for critical reflection on faith, culture, art, and every ordinary-yet-graced square inch of God’s creation.

https://inallthings.org/developing-a-public-justice-perspective/

Gene Networks And Pathways Involved In Escherichia Coli Response To Multiple Stressors, Eman K. Abdelwahed, Nahla A. Hussein, Ahmed Moustafa, Nayera A. Moneib

Faculty Journal Articles

No abstract provided.

Using The Capabilities-Opportunity-Motivation-Behavior (Com-B) System To Conceptualize The Legalization Of Sunday Migratory Game Bird Hunting, Elena C. Rubino, Christopher Serenari

Journal of Rural Social Sciences

Recent wildlife agency efforts aimed at hunter recruitment, retention, and reactivation (R3) are examples of behavior change interventions. Therefore, these R3 programs and policies should be strategically designed to meet hunters’ goals and motivations. We analyzed survey responses (n=808) from North Carolina resident migratory bird hunters regarding potential Sunday hunting legalization to serve as an illustrative case demonstrating how the capabilities-opportunity-motivation-behavior (COM-B) system can be used to conceptualize and more effectively test potential hunter behavior changes prompted by debated R3 strategies. Findings provide decision-makers and land managers with an understanding of the potential implications of migratory game bird Sunday hunting …

Exploring Caregivers’ Perceptions Of Their Trans Children’S Elementary School Experiences, Kylene Phillips

Graduate Theses & Dissertations

A growing body of research reflects the ways in which trans students, who do not adhere to society’s rigid gender binary in practices, policies, and/or norms (Kosciw et. al., 2020; Luecke, 2011; Marine & Nicolazzo, 2014), are ill-served by the current social climates in the majority of our nation’s public schools. Trans students are at a disproportionate risk for harassment, low academic achievement, and school dropout (Payne & Smith, 2018), and transgender individuals experience disparate rates of serious mental health concerns including depression, anxiety, and suicidality (Austin, 2022). Additionally, amid a wave of anti-trans legislation in the United States, the …

Frequency And Longitudinal Course Of Motor Signs In Genetic Frontotemporal Dementia, Sonja Schönecker, Francisco J. Martinez-Murcia, Boris Stephan Rauchmann, Nicolai Franzmeier, Catharina Prix, Elisabeth Wlasich, Sandra V. Loosli, Katja Bochmann, Juan Manuel Gorriz Saez, Robert Laforce, Simon Ducharme, Maria Carmela Tartaglia, Elizabeth Finger, Alexandre De Mendonça, Isabel Santana, Raquel Sanchez-Valle, Fermin Moreno, Sandro Sorbi, Fabrizio Tagliavini, Barbara Borroni, Markus Otto, Matthis Synofzik, Daniela Galimberti, Rik Vandenberghe, John Van Swieten, Christopher Butler, Alexander Gerhard, Caroline Graff, Adrian Danek, Jonathan D. Rohrer

Neuroscience Institute Publications

Background and ObjectivesFrontotemporal dementia (FTD) is a highly heritable disorder. The majority of genetic cases are caused by autosomal dominant pathogenic variants in the chromosome 9 open reading frame 72 (c9orf72), progranulin (GRN), and microtubule-associated protein tau (MAPT) gene. As motor disorders are increasingly recognized as part of the clinical spectrum, the current study aimed to describe motor phenotypes caused by genetic FTD, quantify their temporal association, and investigate their regional association with brain atrophy.MethodsWe analyzed baseline visit data of known carriers of a pathogenic variant in the c9orf72, GRN, or MAPT gene from the Genetic Frontotemporal Dementia Initiative cohort …

Multimodal Single Cell Sequencing Implicates Chromatin Accessibility And Genetic Background In Diabetic Kidney Disease Progression, Parker C Wilson, Yoshiharu Muto, Haojia Wu, Anil Karihaloo, Sushrut S Waikar, Benjamin D Humphreys

2020-Current year OA Pubs

The proximal tubule is a key regulator of kidney function and glucose metabolism. Diabetic kidney disease leads to proximal tubule injury and changes in chromatin accessibility that modify the activity of transcription factors involved in glucose metabolism and inflammation. Here we use single nucleus RNA and ATAC sequencing to show that diabetic kidney disease leads to reduced accessibility of glucocorticoid receptor binding sites and an injury-associated expression signature in the proximal tubule. We hypothesize that chromatin accessibility is regulated by genetic background and closely-intertwined with metabolic memory, which pre-programs the proximal tubule to respond differently to external stimuli. Glucocorticoid excess …

The Rider (2022-09-06), Verilu Infante

The Rider Archives

Vol.8 No.2

Trident - Fall 2022, Dugoni School Of Dentistry

Trident

The newsletter of the Pacific Orthodontic Alumni Chapter at University of the Pacific, Arthur A. Dugoni School of Dentistry.

Fall Enrollment Sets New Benchmarks, Lindenwood University

Archived Lindenwood Press Releases

No abstract provided.

Ungulate Herbivores As Drivers Of Aspen Recruitment And Understory Composition Throughout Arid Montane Landscapes, Elizabeth S. Reikowski, Tyler Refsland, J. Hall Cushman

Aspen Bibliography

Herbivory by wild and domestic ungulates can influence tree recruitment and understory forest communities throughout the world. Herbivore-driven declines in tree recruitment have been observed for quaking aspen (Populus tremuloides), a foundation species whose health and management is recognized as a critical priority throughout much of its range. Livestock fencing is commonly used to promote aspen regeneration, but its effectiveness is rarely assessed, especially across large spatial scales. Using a livestock-reduction experiment, we evaluated the effects of ungulate herbivory on aspen in the Great Basin and southern Cascades, an expansive and environmentally heterogeneous region where aspen faces the …

Intrinsic Disorder In Proteins Associated With Neurodegenerative Diseases, Akshatha Ganne

Theses and Dissertations

A protein’s structure is determined by its amino acid sequence and post-translational modifications, and provides the basis for its physiological functions. Roughly a third of the proteome in mammalian species comprises proteins that contain highly unstructured or intrinsically disordered regions. Proteins with extensive unstructured regions are referred to as intrinsically disordered proteins (IDPs). Recent advances in experimental and computational analyses predicted multiple interacting partners for the disordered regions of proteins, implying critical roles in signal transduction and regulation of biological processes. This dissertation has studied the connection between the misfolding of a protein and an insoluble protein using the ability …

Bradley, Fay, Collection, 1958-1974, Special Collections, Leonard H. Axe Library

Finding Aids

The Fay Bradley Diplomas consists of four diplomas, two for the Independence Community College (Independence, Kansas), one for the Kansas State College of Pittsburg (now Pittsburg State University), one for Howard University (Washington DC).

Fay Bradley was born on January 13, 1938 to Henry and Irene Ransom Bradley in Independence, Kansas. Fay had three sisters and three brothers. His mother worked as a maid and his father worked as a mail router for the Union Gas Station, and as a porter at the Independence Train Depot. Fay started school at the Washington Grade School in Independence. After graduating from Independence …

Non-Toxigenic Clostridium Difficile Spores For Use In Oral Vaccination, Xingmin Sun, Abraham Sonenshein

USF Patents

Described are non-toxigenic Clostridium difficile strains and spores. Also described are vaccines comprising the Clostridium difficile spores. Further described are methods of preventing or treating a Clostridium difficile infection in a subject in need thereof.

Pim1 Promotes Hepatic Conversion By Suppressing Reprogramming-Induced Ferroptosis And Cell Cycle Arrest, Yangyang Yuan, Chenwei Wang, Xuran Zhuang, Shaofeng Lin, Miaomiao Luo, Wankun Deng, Jiaqi Zhou, Lihui Liu, Lina Mao, Wenbo Peng, Jian Chen, Qiangsong Wang, Yilai Shu, Yu Xue, Pengyu Huang

Faculty, Staff and Student Publications

Protein kinase-mediated phosphorylation plays a critical role in many biological processes. However, the identification of key regulatory kinases is still a great challenge. Here, we develop a trans-omics-based method, central kinase inference, to predict potentially key kinases by integrating quantitative transcriptomic and phosphoproteomic data. Using known kinases associated with anti-cancer drug resistance, the accuracy of our method denoted by the area under the curve is 5.2% to 29.5% higher than Kinase-Substrate Enrichment Analysis. We further use this method to analyze trans-omic data in hepatocyte maturation and hepatic reprogramming of human dermal fibroblasts, uncovering 5 kinases as regulators in the two …

A Comparison Of The Effectiveness Of Cocos Nucifera (Coconut) Water As A Rooting Hormone In A Hydroponic And Conventional Set-Up In Growing Ocimum Basilicum (Basil), Trisha Ysabel A. Reodica, Luis Raphael L. Reyes, Fernel Anne J. Cadiz, Jessica Paulyn A. Villa, Pio Jeremiah G. Tagra, Elizabeth Justinne I. Carag, Elisha Jaeriane A. Almeda, Jericho R. Castañeda, Hans Franco A. Amar, Jose Mari M. Calamlam, Gerald B. Gamboa

Sinaya: A Philippine Journal for Senior High School Teachers and Students

Food shortage is still a problem in the Philippines since millions of people may be classified as undernourished. Efforts to augment the insufficiency include developing an efficient planting method as a source of food. This experimental study tested the effectiveness of coconut water as a rooting hormone on hydroponically and conventionally grown basil plants by measuring the height, fresh weight, leaf length, and root length for three weeks, which also served as the dependent variables. Consequently, two (2) hydroponic set-ups and two (2) conventional set-ups utilize a randomized block design. The set-ups containing coconut water served as the independent variables, …

Microrna Expression Levels Change In Neonatal Patients During And After Exposure To Cardiopulmonary Bypass., Lance Hsieh, Lan N. Tu, Alison Paquette, Quanhu Sheng, Shilin Zhao, Douglas C. Bittel, James O'Brien, Kasey Vickers, Peter Pastuszko, Vishal Nigam

Manuscripts, Articles, Book Chapters and Other Papers

Background The systemic inflammation that occurs after exposure to cardiopulmonary bypass (CPB), which is especially severe in neonatal patients, is associated with poorer outcomes and is not well understood. In order to gain deeper insight into how exposure to bypass activates inflammatory responses in circulating leukocytes, we studied changes in microRNA (miRNA) expression during and after exposure to bypass. miRNAs are small noncoding RNAs that have important roles in modulating protein levels and function of cells. Methods and Results We performed miRNA-sequencing on leukocytes isolated from neonatal patients with CPB (n=5) at 7 time points during the process of CPB, …

Effects Of Prior Infection With Sars-Cov-2 On B Cell Receptor Repertoire Response During Vaccination., Elizabeth Fraley, Santosh Khanal, Stephen Pierce, Cas Lemaster, Rebecca Mclennan, Tomi Pastinen, Todd Bradley

Manuscripts, Articles, Book Chapters and Other Papers

Understanding the B cell response to SARS-CoV-2 vaccines is a high priority. High-throughput sequencing of the B cell receptor (BCR) repertoire allows for dynamic characterization of B cell response. Here, we sequenced the BCR repertoire of individuals vaccinated by the Pfizer SARS-CoV-2 mRNA vaccine. We compared BCR repertoires of individuals with previous COVID-19 infection (seropositive) to individuals without previous infection (seronegative). We discovered that vaccine-induced expanded IgG clonotypes had shorter heavy-chain complementarity determining region 3 (HCDR3), and for seropositive individuals, these expanded clonotypes had higher somatic hypermutation (SHM) than seronegative individuals. We uncovered shared clonotypes present in multiple individuals, including …

Microrna Expression Levels Change In Neonatal Patients During And After Exposure To Cardiopulmonary Bypass, Lance Hsieh, Lan N. Tu, Alison Paquette, Quanhu Sheng, Shilin Zhao, Douglas Bittel, James O'Brien, Kasey Vickers, Peter Pastuszko, Vishal Nigam

Faculty and Staff Publications

Background:

The systemic inflammation that occurs after exposure to cardiopulmonary bypass (CPB), which is especially severe in neonatal patients, is associated with poorer outcomes and is not well understood. In order to gain deeper insight into how exposure to bypass activates inflammatory responses in circulating leukocytes, we studied changes in microRNA (miRNA) expression during and after exposure to bypass. miRNAs are small noncoding RNAs that have important roles in modulating protein levels and function of cells.

Methods and Results:

We performed miRNA‐sequencing on leukocytes isolated from neonatal patients with CPB (n=5) at 7 time points during the process of CPB, …

Intouch September 6, 2022, New York Medical College

InTouch

• Industry Leaders to Present at Innovation and Entrepreneurship Conference Set for September 15
• Esther L. Sabban, Ph.D., is Named the Sidney E. Frank Distinguished Professor of Psychiatry and Behavioral Sciences
• Purchasing Office Helps Close Links in Supply Chain
• Race for Rehab Set for October 2
• NYMC and TU Host 21st COVID-19 Symposium
• The Center for Disaster Medicine is an Essential Resource for Emergency Response Education
• Donate Life Club Has Near Record Turnout in First Blood Drive of 2022-2023 Academic Year

Recent Advances On Density Separation Techniques For Microplastic Recovery From Sediments, Andrei Luigi T. Ang, Carlos Miguel D. Jose, Cara Isabel P. Del Rosario, Orrin Landon T. Uy, Joel Garcia

Sinaya: A Philippine Journal for Senior High School Teachers and Students

Microplastics are small plastic fragments commonly less than 5 mm in size (Khatmullina et al., 2016), making up about 92% of the total plastic pollution. Since these plastics are transparent due to their small size, they cause invisible plastic pollution. Due to their adsorptive properties, they can potentially harm marine and human life if ingested. Microplastic extraction is used to isolate microplastics from their original matrix using various methods and instruments to ease the process. Electrostatic separation, magnetization, and pressurized fluid extraction are among the established microplastic extraction methods, but these separation techniques require more effort and use a more …

Development And Validation Of “Hazard O’Clock”: A Home Hazard And Disaster Awareness Game, Reynal M. Penus, Cyron Aris V. Casabuena, Jarl Leander L. Madamba, Erickson F. Del Mundo, Toshio Akira Capintog, Angelo G. Cabic

Sinaya: A Philippine Journal for Senior High School Teachers and Students

The Philippines is the fourth most disaster-prone country in the world due to its location in the Pacific Ring of Fire and Pacific Typhoon Belt. When it comes to these disasters, children below the age of 18 are considered to be among the most vulnerable. This study aimed to develop a mobile game about Disaster Risk Reduction and Management (DRRM) in the home setting that can be used as a teaching aid for children. The information integrated into the game was from different resources made by various government agencies. The Analysis, Design, Development, Implementation, and Evaluation (ADDIE) model was used …

The Impact Of Self-Agitating Anaerobic Batch Digester Design On Biogas Production Of Cattle Manure Co-Digested With Lemna Minor, Aj S. Navarro, Jasmin Eloisa R. Cawaling, Stefan B. Bronoso, Hui L. Cao, Anton Marco G. Carlos, Andrea Dominique J. Garcia, Adrian D. Gendrano, Jessica Mae T. Lee, Ailyn A. Ojeda, Fritz M. Ferran, Christian Jeff G. Cariaga

Sinaya: A Philippine Journal for Senior High School Teachers and Students

The continuation of utilizing fossil fuels as cooking energy sources in rural communities in the Philippines causes more citizens to be at risk of developing numerous health illnesses. This study aimed to propose a potential solution to this problem by innovating a self-agitating anaerobic batch digester, promoting biogas production of cattle manure co-digested with Lemna minor. Two anaerobic batch digester designs, one with baffles and one without, were observed within 22 days to determine the impact of the anaerobic digester design on mixing and biogas production yield. The study contained two pairs of anaerobic batch digesters, the initial and improved …

Utilization Of Varying Colors Of Light Emitting Diodes In Vertical Farms For Solanum Lycopersicum (Tomato), Juliana Marie E. Tamayo, James Phillip B. Ho, Jay Michael T. Carlos, Jose Rene Q. Pinuela, Paolo D. Corrales, Alen Christian R. Koyama, Bianca Maxine F. Lim, Daniel G. Alcantara, Jose Mari M. Calamlam, Gerald B. Gamboa

Sinaya: A Philippine Journal for Senior High School Teachers and Students

In response to climate change and significant decreases of arable land in developing nations, vertical farming has emerged as a suitable alternative to the conventional method of farming with its use of modern technologies such as LED lights. Since previous literature on this subject had mainly focused on the effects of blue and red lights concerning plant growth, this research paper involved 620 nm (pink light), 550 nm (green light), and the combination of the colors in the color spectrum (white light) to expand the scope of the study. The facilities used for the experiment were a multiple-row vertical setup …

Utilization Of Daucus Carota Subsp. Sativus (Carrot) Peels And Oryza Sativa (Rice) As Alternative Materials For Paper Production, Jiwoo Kim, Gabriel Kurt Aguila, Julienna Nicolle B. Espinase, Kyle Ranier T. Fortuna, Ryo G. Hizume, Elaine Jan F. Mendoza, Austin David M. Saldivar, Yujin Yang, Jose Mari M. Calamlam, Gerald B. Gamboa

Sinaya: A Philippine Journal for Senior High School Teachers and Students

The problem of pollution and deforestation have continuously contributed to the mass deterioration of the environment. This study aimed to create paper from rice and carrot wastes tested in a laboratory. The study followed an experimental research design, utilizing TAPPI T-220 test methods and ISO standard procedures. The paper sheets were tested under four quality tests: paper tear index, folding endurance, grammage, and paper burst strength. Data gathered from laboratory tests were statistically analyzed via the independent t-test. It was found that rice papers had a higher paper tear index (4.99 mN.m^2/g), folding endurance (3.81 folds), and paper burst strength …

Evaluation Of Bio Briquettes Made From Musa Acuminata Colla, Musa Acuminata And Musa Balbisiana Silk, And Citrus Reticulata And Citrus Sinensis Peels, Allegra Fatima R. Genuino, Janella Marie M. Tancuan, Quiara F. Ventura, Andrea Li S. Santos, Kariane Kyle R. Foo, Xavier Augusto Maria F. Samaco, Lucas Thaddeus A. Armada, Gavin Liam F. Lemoncito, Matthew Irwin B. Padrique, Gerard Deniel P. Almira, Antonio Rafael C. Torres, Jose Mari M. Calamlam, Gerald B. Gamboa

Sinaya: A Philippine Journal for Senior High School Teachers and Students

Accumulation of food waste and the burning of coal emit harmful chemicals which contribute to environmental problems such as climate change and global warming. These also risk the health of people, which causes deaths. Briquettes help improve and preserve the environment by lessening food waste and coal emissions. This study aims to determine the best treatment for briquettes to help disadvantaged communities and alleviate the adverse effects on the environment and health. A combination of banana (Musa acuminata Colla (AA Group) 'Lakatan' and Musa acuminata × M. balbisiana (AAB Group) 'Silk', and orange (Citrus × reticulata and Citrus × sinensis) …

Follicular Lymphoma Microenvironment Characteristics Associated With Tumor Cell Mutations And Mhc Class Ii Expression, Guangchun Han, Qing Deng, Mario L Marques-Piubelli, Enyu Dai, Minghao Dang, Man Chun John Ma, Xubin Li, Haopeng Yang, Jared Henderson, Olga Kudryashova, Mark Meerson, Sergey Isaev, Nikita Kotlov, Krystle J Nomie, Alexander Bagaev, Edwin R Parra, Luisa M Solis Soto, Simrit Parmar, Fredrick B Hagemeister, Sairah Ahmed, Swaminathan P Iyer, Felipe Samaniego, Raphael Steiner, Luis Fayad, Hun Lee, Nathan H Fowler, Christopher R Flowers, Paolo Strati, Jason R Westin, Sattva S Neelapu, Loretta J Nastoupil, Francisco Vega, Linghua Wang, Michael R Green

Faculty, Staff and Student Publications

Follicular lymphoma (FL) is a B-cell malignancy with a complex tumor microenvironment that is rich in nonmalignant immune cells. We applied single-cell RNA sequencing to characterize the diverse tumor and immune cell populations of FL and identified major phenotypic subsets of FL T cells, including a cytotoxic CD4 T-cell population. We characterized four major FL subtypes with differential representation or relative depletion of distinct T-cell subsets. By integrating exome sequencing, we observed that somatic mutations are associated with, but not definitive for, reduced MHC expression on FL cells. In turn, expression of MHCII genes by FL cells was associated with …