Digital Commons Network^™

Molecular Diagnostic Survey Of Honey Bee, Apis Mellifera L., Pathogens And Parasites From Arkansas, Usa, Dylan Cleary, Allen L. Szalanski

Entomology Faculty Publications and Presentations

Managed honey bee populations have fluctuated over the past several decades in the U.S. While a single factor has not been identified for these losses, the interaction between multiple biotic and abiotic stressors have been suggested to be responsible. Of major concern are several invasive parasite and pathogen species as well as colony management. A single honey bee colony often suffers from multiple harmful agents, that may act synergistically and cause greater declines in bee health. We conducted a survey to detect known and lesser-known honey bee parasites and pathogens. While previous research has primarily focused on commercially managed colonies, …

On The Scaling Properties Of Oscillatory Modes With Balanced Energy, Dobromir Dotov

Journal Articles

Animal bodies maintain themselves with the help of networks of physiological processes operating over a wide range of timescales. Many physiological signals are characterized by 1/f scaling where the amplitude is inversely proportional to frequency, presumably reflecting the multi-scale nature of the underlying network. Although there are many general theories of such scaling, it is less clear how they are grounded on the specific constraints faced by biological systems. To help understand the nature of this phenomenon, we propose to pay attention not only to the geometry of scaling processes but also to their energy. The first key assumption …

Omics Analyses Of A Somatic Trp53r245w/+ Breast Cancer Model Identify Cooperating Driver Events Activating Pi3k/Akt/Mtor Signaling, Xiaojie Yu, Yun Zhang, Shunbin Xiong, Joy M Mcdaniel, Chang Sun, Gilda P Chau, Jovanka Gencel-Augusto, Dhruv Chachad, Rhiannon L Morrissey, Xiayu Rao, Jing Wang, Guillermina Lozano

Faculty, Staff and Student Publications

Alterations of the tumor suppressor

Exploring Engagement And Persistence Through The Lens Of Student Experiences In A Sonography Program, Josephine Elizabeth Peck

USF Tampa Graduate Theses and Dissertations

The juxtaposition of the increased current and future demand for Diagnostic Medical Sonographers and high attrition rates in many sonography programs emphasizes the need for colleges to do more to educate and train sonography practitioners who are prepared to enter the healthcare workforce. Additionally, a gap exists in understanding student engagement and persistence in Sonography programs. By filling this gap, pertinent answers about student success or lack thereof in these Sonography programs can be addressed.

This basic qualitative study aims to explore student engagement and persistence through the prism of their experiences in AS(DMS) programs at four-year state colleges in …

Antibody-Drug Conjugates For The Treatment Of Her2-Positive Breast Cancer, Mariana K Najjar, Sara G Manore, Angelina T Regua, Hui-Wen Lo

Faculty, Staff and Student Publications

Human epidermal growth factor receptor 2 (HER2) receptor tyrosine kinase is overexpressed in 20–30% of breast cancers and is associated with poor prognosis and worse overall patient survival. Most women with HER2-positive breast cancer receive neoadjuvant chemotherapy plus HER2-targeted therapies. The development of HER2-directed therapeutics is an important advancement in targeting invasive breast cancer. Despite the efficacy of anti-HER2 monoclonal antibodies, they are still being combined with adjuvant chemotherapy to improve overall patient outcomes. Recently, significant progress has been made towards the development of a class of therapeutics known as antibody-drug conjugates (ADCs), which leverage the high specificity of HER2-targeted …

A High-Resolution 3d Atlas Of The Spectrum Of Tuberculous Andcovid-19 Lung Lesions, Gordon Wells, Joel N Glasgow, Kievershen Nargan, Kapongo Lumamba, Rajhmun Madansein, Kameel Maharaj, Leon Y Perumal, Malcolm Matthew, Robert L Hunter, Hayden Pacl, Jacelyn E Peabody Lever, Denise D Stanford, Satinder P Singh, Prachi Bajpai, Upender Manne, Paul V Benson, Steven M Rowe, Stephan Le Roux, Alex Sigal, Muofhe Tshibalanganda, Carlyn Wells, Anton Du Plessis, Mpumelelo Msimang, Threnesan Naidoo, Adrie J C Steyn

Faculty, Staff and Student Publications

Our current understanding of the spectrum of TB and COVID-19 lesions in the human lung is limited by a reliance on low-resolution imaging platforms that cannot provide accurate 3D representations of lesion types within the context of the whole lung. To characterize TB and COVID-19 lesions in 3D, we applied micro/nanocomputed tomography to surgically resected, postmortem, and paraffin-embedded human lung tissue. We define a spectrum of TB pathologies, including cavitary lesions, calcium deposits outside and inside necrotic granulomas and mycetomas, and vascular rearrangement. We identified an unusual spatial arrangement of vasculature within an entire COVID-19 lobe, and 3D segmentation of …

A Randomized Pilot Study Of Oncology Massage To Treat Chemotherapy-Induced Peripheral Neuropathy, Gabriel Lopez, Cathy Eng, Michael Overman, David Ramirez, Wenli Liu, Curtiss Beinhorn, Pamela Sumler, Sarah Prinsloo, Yisheng Li, Minxing Chen, Eduardo Bruera, Lorenzo Cohen

Faculty, Staff and Student Publications

This pilot randomized controlled trial investigated massage therapy for symptomatic relief of chemotherapy-induced peripheral neuropathy (CIPN) to determine the ideal weekly frequency and number of weeks of providing massage. We evaluated the feasibility and initial efficacy of a Swedish massage protocol to treat lower extremity (LE) CIPN. Inclusion criteria: LE neuropathy attributed to oxaliplatin, paclitaxel, or docetaxel, with no other attributable causes; ≥ 6 months since last chemotherapy; self-reported neuropathy score ≥ 3, 0-10 scale; age ≥ 18. Participant randomization (2:2:1:1) to one of four groups: LE (2) or head/neck/shoulder (control; 1) massage 3 times (3X) a week for 4 …

Ornithine Decarboxylase Supports Ilc3 Responses In Infectious And Autoimmune Colitis Through Positive Regulation Of Il-22 Transcription, Vincent Peng, Siyan Cao, Tihana Trsan, Jennifer K Bando, Julian Avila-Pacheco, John L Cleveland, Clary Clish, Ramnik J Xavier, Marco Colonna

2020-Current year OA Pubs

Group 3 innate lymphoid cells (ILC3s) are RORγT

Selective Foraging Behavior Of Seabirds In Small‐Scale Slicks, Lilian Lieber, Cynthia Füchtencordsjürgen, Rebecca L. Hilder, Paula J. Revering, Ina Siekmann, Roland Langrock, Wam Nimmo‐Smith

School of Biological and Marine Sciences

Marine predator foraging opportunities are often driven by dynamic physical processes enhancing prey accessibility. Surface slicks are ubiquitous yet ephemeral ocean features where convergent flows accumulate flotsam, concentrating marine organisms and pollutants. Slicks can manifest on the sea surface as meandering lines and seabirds often associate with slicks. Yet, how slicks may influence the fine-scale foraging behavior of seabirds is only coarsely resolved. Here we show that seabirds selectively forage in small-scale slicks. We used aerial drone technology to track surface-foraging terns (Sternidae, 107 tracks) over evolving slicks advected by the mean flow and reshaped by localized turbulence at scales …

Surgical Resection Of A Rare Primary Retroperitoneal Mucinous Borderline Tumor Of Müllerian Origin: A Case Report, Taylor R. Kavanagh, Nneamaka Nwaoduah, Scott D. Richard, Wilbur Bowne, Norman G Rosenblum

Department of Obstetrics and Gynecology Faculty Papers

•Primary retroperitoneal mucinous tumors (PRMTs) are a rare group of cystic neoplasms consisting of three subtypes.•PRMTs are histologically similar to ovarian mucinous tumors but lack true ovarian tissue.•PRMTs should be considered in the differential diagnosis when encountering retroperitoneal cystic lesions.•During surgical resection tumor disruption should be avoided.•Surgical resection alone provides durable disease control for mucinous borderline tumors of low malignant potential.

Ucc Minutes 11-8-22, Angela Brock

UCC Agendas/Minutes

No abstract provided.

Two Neuronal Peptides Encoded From A Single Transcript Regulate Mitochondrial Complex Iii In Drosophila, Justin A Bosch, Berrak Ugur, Israel Pichardo-Casas, Jordan Rabasco, Felipe Escobedo, Zhongyuan Zuo, Ben Brown, Susan Celniker, David A Sinclair, Hugo J Bellen, Norbert Perrimon

Duncan NRI Faculty and Staff Publications

Naturally produced peptides (<100 amino acids) are important regulators of physiology, development, and metabolism. Recent studies have predicted that thousands of peptides may be translated from transcripts containing small open-reading frames (smORFs). Here, we describe two peptides in Drosophila encoded by conserved smORFs, Sloth1 and Sloth2. These peptides are translated from the same bicistronic transcript and share sequence similarities, suggesting that they encode paralogs. Yet, Sloth1 and Sloth2 are not functionally redundant, and loss of either peptide causes animal lethality, reduced neuronal function, impaired mitochondrial function, and neurodegeneration. We provide evidence that Sloth1/2 are highly expressed in neurons, imported to mitochondria, and regulate mitochondrial complex III assembly. These results suggest that phenotypic analysis of smORF genes in Drosophila can provide a wealth of information on the biological functions of this poorly characterized class of …

Genetic Addiction Risk Severity Assessment Identifies Polymorphic Reward Genes As Antecedents To Reward Deficiency Syndrome (Rds) Hypodopaminergia's Effect On Addictive And Non-Addictive Behaviors In A Nuclear Family, Catherine A Dennen, Kenneth Blum, Abdalla Bowirrat, Panayotis K Thanos, Igor Elman, Mauro Ceccanti, Rajendra D Badgaiyan, Thomas Mclaughlin, Ashim Gupta, Anish Bajaj, David Baron, B William Downs, Debasis Bagchi, Mark S Gold

2020-Current year OA Pubs

This case series presents the novel genetic addiction risk score (GARS), which shows a high prevalence of polymorphic risk alleles of reward genes in a nuclear family with multiple reward deficiency syndrome (RDS) behavioral issues expressing a hypodopaminergic antecedent. The family consists of a mother, father, son, and daughter. The mother experienced issues with focus, memory, anger, and amotivational syndrome. The father experienced weight issues and depression. The son experienced heavy drinking, along with some drug abuse and anxiety. The daughter experienced depression, lethargy, brain fog, focus issues, and anxiety, among others. A major clinical outcome of the results presented …

The Evolution, Current Indications And Outcomes Of Cementless Total Knee Arthroplasty, Maria T Schwabe, Charles P Hannon

2020-Current year OA Pubs

Total knee arthroplasty (TKA) has been performed by orthopedic surgeons for decades, but the cementless TKA has only recently gained much interest in the world of arthroplasty. Initially, early designs had multiple complications, particularly with aseptic loosening due to osteolysis and micromotion. However, modifications have shown good outcomes and excellent survivorship. Over the last several decades, changes in implant designs as well as implant materials/coatings have helped with bone in growth and stability. Furthermore, surgeons have been performing TKA in younger and more obese patients as these populations have been increasing. Good results from the cementless TKA compared to cemented …

Finding Aid For The Buildings & Grounds Collection (Mum00525)

Archives & Special Collections: Finding Aids (alphabetical)

Collection contains dedication programs and invitations, correspondence, speeches, and postcards related to various buildings on the University of Mississippi campus. Items were created 1907-2002.

Finding Aid For The Mississippi Conservation & Recreation Collection (Mum00303)

Archives & Special Collections: Finding Aids (alphabetical)

Collection contains magazines and articles related to conservation and recreation in Mississippi. Items were created 1938-1984.

Finding Aid For The American Association Of University Women Collection (Mum00007)

Archives & Special Collections: Finding Aids (alphabetical)

Collection contains branch materials, correspondence, branch reports, newspaper clippings, yearbooks, minutes, state convention reports, bylaws, constitutions, financial records, scrapbooks, journals, audiovisual material, and photographs related to the American Association of University Women. These materials are dated 1899-2000.

Cougars In The Eastern United States, Justina Raleva, Kenneth Rieche

Scholars Week

Since the 1900s, cougars have been extirpated from nearly everywhere except the western United States parks and wilderness areas. In recent years, cougars have been starting to spread their range outside of the Rocky Mountains, towards eastern states like Illinois, Missouri, and Louisiana. The purpose of this project is to conduct outreach and education through a brochure that would educate locals in Kentucky and Tennessee regarding cougar safety and conservation importance.

Retrieve, Race, Release, Karamello Young, Paige Mccord, Madison Morrison, Emily Fitzgerald

Scholars Week

Title: Retrieve, Race, Release

by: Paige McCord, Karamello Young, Madison Morrison, Emily Fitzgerald

Abstract: This poster represents a service-learning project that was done for our conservation biology class. Our main goal is to educate the public about the negative impacts of turtle derbies. We did this by using educational materials to raise awareness about turtle races and the impact of painting them with toxic substances before releasing them into a habitat that is not their natural one. We did not seek out to prohibit or stop the races as that would cause people to shut down and not listen as …

Organizational Support Factors For Minor League Baseball Player Development, Christopher M. Mcleod, Nola Agha, Simon Rosenblum-Larson

Journal of Athlete Development and Experience

This study examines organizational support in the context of minor league baseball to better understand how organizations can support athletes’ development. Exploratory results show that English and Spanish players identify salary/pay, off-season training opportunities, and nutritious food as their most important unmet development needs. English and Spanish respondents differently prioritized playing opportunities, communication with front office staff, health care, and equipment as unmet needs. Explanatory results show that organizational support factors (private problem support and second career support) explain 17% of the variation in minor league baseball players’ self-perceptions of development. The results provide guidance for Major League Baseball and …

Episode 34: Stella Sung: Combining Art And Technology, University Of Central Florida

Knights Do That Podcast Transcripts

Season three of Knights Do That, UCF’s official podcast, returns with its seventh guest, Stella Sung, a renowned composer, Pegasus Professor, trustee chair professor, and director of the Center for Research and Education in Arts, Technology and Entertainment (CREATE) at UCF. Sung started her career at UCF as a music professor and now teaches in the School of Visual Arts and Design, where she encourages students to stay on the cutting edge of art across all forms.

Here she shares the importance of integrating science and the arts, as well as her research on using virtual and augmented reality …

Optical Classification Of An Urbanized Estuary Using Hyperspectral Remote Sensing Reflectance, Kyle J. Turner, Maria Tzortziou, Brice K. Grunert, Joaquim Goes, Jonathan Sherman

Biological, Geological, and Environmental Faculty Publications

Optical water classification based on remote sensing reflectance (Rrs(.)) data can provide insight into water components driving optical variability and inform the development and application of bio-optical algorithms in complex aquatic systems. In this study, we use an in situ dataset consisting of hyperspectral Rrs(.) and other biogeochemical and optical parameters collected over nearly five years across a heavily urbanized estuary, the Long Island Sound (LIS), east of New York City, USA, to optically classify LIS waters based on Rrs(.) spectral shape. We investigate the similarities and differences of discrete groupings (k-means clustering) and continuous spectral indexing using the Apparent …

The Utah Statesman, November 7, 2022, Utah State University

The Utah Statesman

Weekly student newspaper of Utah State University in Logan.

Jitney

Theatre and Performance Studies Programs

It is 1977 in a Black neighborhood of Pittsburgh known as the Hill District. Drivers of unlicensed cabs (jitneys) fight for love, survival, and respect as the powers-that-be threaten to close down their garage in the name of neighborhood improvement.

Though Jitney is one of August Wilson’s first plays, it was the last of his 10-play American Century Cycle to premiere on Broadway. Using Wilson’s characteristically rich language, Jitney explores what happens when tempers flare, potent secrets are revealed, and the fragile threads that bind people together threaten to come undone.

A Novel Vaccine Candidate Against Rabbit Hemorrhagic Disease Virus 2 (Rhdv2) Confers Protection In Domestic Rabbits, Angela M. Bosco-Lauth, Bethany Cominsky, Stephanie Porter, J. Jeffrey Root, Amber Schueler, Gary Anderson, Sara Vanderwal, Andy Benson

United States Department of Agriculture Wildlife Services: Staff Publications

OBJECTIVE To evaluate efficacy of a novel vaccine against rabbit hemorrhagic disease virus 2 (RHDV2) in domestic rabbits.

ANIMALS 40 New Zealand White rabbits obtained from a commercial breeder.

PROCEDURES Rabbits were vaccinated and held at the production facility for the duration of the vaccination phase and transferred to Colorado State University for challenge with RHDV2. Rabbits were challenged with oral suspensions containing infectious virus and monitored for clinical disease for up to 10 days. Rabbits that died or were euthanized following infection were necropsied, and livers were evaluated for viral RNA via RT-PCR.

RESULTS None of the vaccinated animals …

2022 November 7 - Faculty Senate Agenda And Minutes, Faculty Senate, East Tennessee State University

Faculty Senate Agendas and Minutes

No abstract provided.

The Rider (2022-11-07), Verilu Infante

The Rider Archives

Vol.8 No.11

Student Social Entrepreneurs Grab Opportunities And Run With Knowledge Gained, Sustainability Institute

Sustainability Institute Blog

No abstract provided.

The Nogo Receptor Ngr2, A Novel Αvβ3 Integrin Effector, Induces Neuroendocrine Differentiation In Prostate Cancer, Fabio Quaglia, Shiv Ram Krishn, Khalid Sossey-Alaoui, Priyanka Shailendra Rana, Elzbieta Pluskota, Pyung Hun Park, Christopher D. Shields, Stephen Lin, Peter Mccue, Andrew V. Kossenkov, Yanqing Wang, David W. Goodrich, Sheng-Yu Ku, Himisha Beltran, William K. Kelly, Eva Corey, Maja Klose, Christine Bandtlow, Qin Liu, Dario C. Altieri, Edward F. Plow, Lucia R. Languino

Department of Cancer Biology Faculty Papers

Androgen deprivation therapies aimed to target prostate cancer (PrCa) are only partially successful given the occurrence of neuroendocrine PrCa (NEPrCa), a highly aggressive and highly metastatic form of PrCa, for which there is no effective therapeutic approach. Our group has demonstrated that while absent in prostate adenocarcinoma, the αVβ3 integrin expression is increased during PrCa progression toward NEPrCa. Here, we show a novel pathway activated by αVβ3 that promotes NE differentiation (NED). This novel pathway requires the expression of a GPI-linked surface molecule, NgR2, also known as Nogo-66 receptor homolog 1. We show here that NgR2 is upregulated by αVβ3, …

Differential Expression And Activities Of Cytochrome P450 3a In The Rat Brain Microsomes And Mitochondria, Nouf Alshammari, Devaraj Venkatapura Chandrashekar, Mamunur Rashid, Reza Mehvar

Pharmacy Faculty Articles and Research

Midazolam (MDZ), a benzodiazepine derivative, is metabolized to 1′- and 4-hydroxylated metabolites (1′-OH-MDZ and 4-OH-MDZ, respectively) by cytochrome P450 3A (CYP3A). The purpose of this study was to investigate the CYP3A-mediated hydroxylation of MDZ in the rat brain mitochondria (MT). Brain microsomes (MC) and MT fractions were prepared from rats (n = 8) using differential and density gradient centrifugations, and the purity of the fractions was evaluated using VDAC1 and calreticulin as markers of MT and MC, respectively. The formation rates of 1′-OH-MDZ and 4-OH-MDZ in the rat brain MC and MT samples were determined using an LC–MS/MS method …