Digital Commons Network^™

Multiomics Approach Captures Hepatic Metabolic Network Altered By Chronic Ethanol Administration, Isin Tuna Sakallioglu, Bridget Tripp, Jacy Kubik, Carol A. Casey, Paul G. Thomes, Robert Powers

Department of Chemistry: Faculty Publications

Using a multiplatform and multiomics approach, we identified metabolites, lipids, proteins, and metabolic pathways that were altered in the liver after chronic ethanol administration. A functional enrichment analysis of the multiomics dataset revealed that rats treated with ethanol experienced an increase in hepatic fatty acyl content, which is consistent with an initial development of steatosis. The nuclear magnetic resonance spectroscopy (NMR) and liquid chromatography–mass spectrometry (LC-MS) metabolomics data revealed that the chronic ethanol exposure selectively modified toxic substances such as an increase in glucuronidation tyramine and benzoyl; and a depletion in cholesterol-conjugated glucuronides. Similarly, the lipidomics results revealed that ethanol …

Fighting Words: Catalonia At The Language Instruction Crossroads, Jane Tien

Duke Journal of Comparative & International Law

The schism between Spain and Catalonia obscures a struggle over the teaching language for non-linguistic subjects in Catalonia's public schools. The recent two decades decanted into Catalan society two Spanish Constitutional Court rulings mandating a Castilian-Catalan conjunctive instruction model—with Catalan as the "center of gravity"—and tasking the Catalan legislature with configuring that "center." Pleasing none and spurned by all, the Constitutional Court duology emboldened activist lower courts to bypass the Catalan legislature, while schools in Catalonia continued to teach almost exclusively in Catalan. With the Castilians alienated and the Catalans defiant, language instruction in Catalonia turned into a festering wound …

The Stockholm Paradigm Explains The Dynamics Of Darwin’S Entangled Bank, Including Emerging Infectious Disease, Salvatore J. Agosta

MANTER: Journal of Parasite Biodiversity

Pathogens and their hosts are embedded within the larger biosphere, what Darwin called the “entangled bank.” Emerging infectious disease occurs when a parasite “switches” to a new host. Understanding the dynamics of emerging disease requires understanding the dynamics of host-switching, which requires a more general understanding of how the biosphere and its constituent members cope when conditions change. The Stockholm paradigm is an integrative evolutionary framework that describes how living systems cope with change by oscillating between exploiting and exploring the geographical and functional dimensions of their environments. It combines organismal capacity, ecological opportunity, and the repeated external perturbations to …

Yield Prediction Through Integration Of Genetic, Environment, And Management Data Through Deep Learning, Daniel R. Kick, Jason G. Wallace, James C. Schnable, Judith M. Kolkman, Barış Alaca, Timothy M. Beissinger, Jode Edwards, David Ertl, Sherry Flint-Garcia, Joseph L. Gage, Candice N. Hirsch, Joseph E. Knoll, Natalia De Leon, Dayane C. Lima, Danilo E. Moreta, Maninder P. Singh, Addie Thompson, Teclemariam Weldekidan, Jacob D. Washburn

Department of Agronomy and Horticulture: Faculty Publications

Accurate prediction of the phenotypic outcomes produced by different combinations of genotypes, environments, and management interventions remains a key goal in biology with direct applications to agriculture, research, and conservation. The past decades have seen an expansion of new methods applied toward this goal. Here we predict maize yield using deep neural networks, compare the efficacy of 2 model development methods, and contextualize model performance using conventional linear and machine learning models. We examine the usefulness of incorporating interactions between disparate data types. We find deep learning and best linear unbiased predictor (BLUP) models with interactions had the best overall …

Collaborative Interprofessional Health Science Student Led Realistic Mass Casualty Incident Simulation, Deborah L Mccrea, Robert C Coghlan, Tiffany Champagne-Langabeer, Stanley Cron

Faculty, Staff and Student Publications

In collaboration, a health science university and a fire department offered a mass casualty incident (MCI) simulation. The purpose of this study was to evaluate a cross-section of student health care providers to determine their working knowledge of an MCI. Students were given a pretest using the Emergency Preparedness Information Questionnaire (EPIQ) and the Simple Triage and Rapid Transport (START) Quiz. The EPIQ instrument related to knowledge of triage, first aid, bio-agent detection, critical reporting, incident command, isolation/quarantine/decontamination, psychological issues, epidemiology, and communications. The START Quiz gave 10 scenarios. Didactic online content was given followed by the simulation a few …

Analysing Association Rates Of Reef Manta Rays (Mobula Alfredi) Situated In Chagos Archipelago, Lena Pollett

The Plymouth Student Scientist

Reef manta rays (Mobula alfredi) are in rapid decline and threatened by multiple anthropogenic pressures. Conservation of this vulnerable marine species requires an understanding of the drivers of their movement patterns and group structuring. Aggregations have been presumed to be a function of resource availability. However, recent studies have suggested that association rates within these areas of aggregation may underpin social behaviour, furthering our understanding of these species' movement and social networking. Here we used acoustic telemetry technology to assess the extent that a group of 26 M. alfredi associates within Egmont Atoll, situated within the Chagos Archipelagos, over a …

Biological Recruitment On Static And Boat Hull Panels Coated With Non-Toxic Fibre Flock, Julia Hinrichs

The Plymouth Student Scientist

Marine biofouling, the settlement of aquatic organisms on submerged surfaces, creates an estimated cost of 20 billion USD annually for the shipping industry in increased fuel consumption due to overgrowth. However, the existing antifouling solutions are being restricted by international organisations due to their adverse effects on the marine environment. In recent years, the research focus has shifted to non-toxic methods highlighting the importance of settlement cues of invertebrates. Biofoulers, such as invertebrate larvae and algal spores have been shown to respond to physical cues such as surface structure. The aim of this study was to test the environmentally friendly …

The Effect Of Seagrass Components On The Associated Bacterial Diversity And Antimicrobial Activity In Zostera Marina, Caroline Millan

The Plymouth Student Scientist

Seagrasses are marine angiosperms located in intertidal and sub-tidal waters. They are important ecosystem engineers that play a crucial role in the structure of habitats, allowing them to support a comprehensive diversity of life. Through fundamental ecological processes and the generation of niches, each seagrass species has aggregated an associated microbiome that lives among the various seagrass components and exhibit symbiotic relations. There have been studies investigating the diversity of the associated bacteria and elements of the resulting microbial activity, however these have primarily focused on tropical seagrass species and have failed to examine the extent of this bioactivity. This …

Investigating The Impacts Of Heterotrophic Nutrition On Acropora Microclados, Heather O'Keefe

The Plymouth Student Scientist

The Scleractinian coral Acropora microclados is a commercially important species that functions as both an autotroph and heterotroph. In ex situ coral aquaculture, elucidating an optimal diet to improve growth and resilience is critical in improving the sustainability and success of rearing corals for trade and conservation. To investigate the impacts of diet on A. microclados, three groups of 15 nubbins were kept under three different feeding regimes for three months at the National Marine Aquarium, Plymouth, UK. One group was fed nothing, the control (CTL), one group fed Artemia salina nauplii (ART) and one group fed a mixed diet …

Public Engagement In Environmental Issues: Investigating Factors Of Disengagement From An Individual And Organisational Perspective, Anna Carne

The Plymouth Student Scientist

Anthropogenic climate change is now a major issue facing the public, government, and environmental non-governmental organisations (ENGOs) alike. In order for climate goals set out by the conference of the parties (COP) summits to be reached, the public must be involved and feel a sense of responsibility to act. Though there have been previous studies investigating the levels of engagement and the actions that individuals take, the impact of certain factors on engagement is still not well understood. A UK survey open for two weeks and shared on social media was conducted. The survey consisted of open and closed questions …

Marine Mammals In The Western English Channel, A Survey From The Rame Head Peninsula, Janine Douglas

The Plymouth Student Scientist

This paper presents the first records of marine mammals in Plymouth Sound National Marine Park (NMP), and over 1000 individual animal observations were recorded. Marine mammal temporal and spatial distributions were quantified for the first time at Rame Head, a vantage point overlooking the NMP and the Western English Channel. A biodiversity hotspot, the Western English Channel supports many species of marine mammals, yet it is subject to increasing anthropogenic pressures, such as heavy shipping, which could significantly impact populations. Whilst marine mammals are well studied, their distributions and population sizes remain largely unknown; effective conservation of these animals requires …

Information Retrieval Skills As Correlate Of Scholarly Research Among Postgraduate Students In Selected Universities In Oyo And Lagos States, Nigeria, Kolawole Oluwatola, Lawrence Akingbade

Library Philosophy and Practice (e-journal)

Abstract

The main objective of the study is to investigate information retrieval skills as correlate of scholarly research among postgraduate students in selected Universities in Oyo and Lagos States, Nigeria. Survey research methodology was used with a total sample size of 379 using single random sampling techniques to select postgraduate students. Data was collected mainly through questionnaire and analyzed using frequency distribution and regression analysis run on SPSS (2.0). The result revealed the types of information retrieval skills, the study revealed that information retrieval skills highly influence the postgraduate students’ scholarly research as it allowed them to easily recognition their …

Highly Efficient Photocatalysts For Methylene Blue Degradation Based On A Platform Of Deposited Go-Zno Nanoparticles On Polyurethane Foam, Mohamed Morsy

Nanotechnology Research Centre

No abstract provided.

Risk Factors For Sars-Cov-2 Transmission In Close Contacts Of Adults At High Risk Of Infection Due To Occupation: Results From The Contact Tracing Strategy Of The Covida Epidemiological Surveillance Study In Bogotá, Colombia, In 2020-2021, Andrea Ramírez Varela, Sandra Contreras-Arrieta, Guillermo Tamayo-Cabeza, Leonardo Salas Zapata, Yuldor Caballero-Díaz, Luis Jorge Hernández Florez, Andrés Patiño Benavidez, Rachid Laajaj, Fernando De La Hoz, Giancarlo Buitrago Gutierrez, Silvia Restrepo, Eduardo Behrentz

Faculty, Staff and Student Publications

OBJECTIVES: To estimate the risk factors for SARS-CoV-2 transmission in close contacts of adults at high risk of infection due to occupation, participants of the CoVIDA study, in Bogotá D.C., Colombia.

SETTING: The CoVIDA study was the largest COVID-19 intensified sentinel epidemiological surveillance study in Colombia thus far, performing over 60 000 RT-PCR tests for SARS-CoV-2 infection. The study implemented a contact tracing strategy (via telephone call) to support traditional surveillance actions performed by the local health authority.

PARTICIPANTS: Close contacts of participants from the CoVIDA study.

PRIMARY AND SECONDARY OUTCOME MEASURES: SARS-CoV-2 testing results were obtained (RT-PCR with CoVIDA …

Multiomics Characterization Of Methicillin-Resistant Staphylococcus Aureus (Mrsa) Isolates With Heterogeneous Intermediate Resistance To Vancomycin (Hvisa) In Latin America, Betsy E Castro, Rafael Rios, Lina P Carvajal, Mónica L Vargas, Mónica P Cala, Lizeth León, Blake Hanson, An Q Dinh, Oscar Ortega-Recalde, Carlos Seas, Jose M Munita, Cesar A Arias, Sandra Rincon, Jinnethe Reyes, Lorena Diaz

Faculty, Staff and Student Publications

BACKGROUND: Heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) compromise the clinical efficacy of vancomycin. The hVISA isolates spontaneously produce vancomycin-intermediate Staphylococcus aureus (VISA) cells generated by diverse and intriguing mechanisms.

OBJECTIVE: To characterize the biomolecular profile of clinical hVISA applying genomic, transcriptomic and metabolomic approaches.

METHODS: 39 hVISA and 305 VSSA and their genomes were included. Core genome-based Bayesian phylogenetic reconstructions were built and alterations in predicted proteins in VISA/hVISA were interrogated. Linear discriminant analysis and a Genome-Wide Association Study were performed. Differentially expressed genes were identified in hVISA-VSSA by RNA-sequencing. The undirected profiles of metabolites were determined by liquid chromatography and …

Control Of Sars-Cov-2 Infection By Mt1-Mmp-Mediated Shedding Of Ace2, Xuanming Guo, Jianli Cao, Jian-Piao Cai, Jiayan Wu, Jiangang Huang, Pallavi Asthana, Sheung Kin Ken Wong, Zi-Wei Ye, Susma Gurung, Yijing Zhang, Sheng Wang, Zening Wang, Xin Ge, Hiu Yee Kwan, Aiping Lyu, Kui Ming Chan, Nathalie Wong, Jiandong Huang, Zhongjun Zhou, Zhao-Xiang Bian, Shuofeng Yuan, Hoi Leong Xavier Wong

Faculty, Staff and Student Publications

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global pandemic. Angiotensin-converting enzyme 2 (ACE2) is an entry receptor for SARS-CoV-2. The full-length membrane form of ACE2 (memACE2) undergoes ectodomain shedding to generate a shed soluble form (solACE2) that mediates SARS-CoV-2 entry via receptor-mediated endocytosis. Currently, it is not known how the physiological regulation of ACE2 shedding contributes to the etiology of COVID-19 in vivo. The present study identifies Membrane-type 1 Matrix Metalloproteinase (MT1-MMP) as a critical host protease for solACE2-mediated SARS-CoV-2 infection. SARS-CoV-2 infection leads to increased activation of MT1-MMP that is colocalized with ACE2 in human lung …

Behavioral Strategies Of Prehistoric And Historic Children From Dental Microwear Texture Analysis, Almudena Estalrrich, Kristin L. Krueger

Anthropology: Faculty Publications and Other Works

Reconstructing the dietary and behavioral strategies of our hominin ancestors is crucial to understanding their evolution, adaptation, and overall way of life. Teeth in general, and dental microwear specifically, provide a means to examine these strategies, with posterior teeth well positioned to tell us about diet, and anterior teeth helping us examine non-dietary tooth-use behaviors. Past research predominantly focused on strategies of adult individuals, leaving us to wonder the role children may have played in the community at large. Here we begin to address this by analyzing prehistoric and historic children through dental microwear texture analysis of deciduous anterior teeth.

Some Reflections On The “New Law Of The Sea”, Philippe Gautier

International Law Studies

The fortieth anniversary of the opening for signature of the UN Convention on the Law of the Sea provides an opportunity to offer some reflections on the “new law of the sea”; that is, the comprehensive set of rules that was the result of an unprecedented multilateral negotiation process: the Third United Nations Conference on the Law of the Sea (1973–1982). The focus of this article is on the adjudication of sea-related disputes in the “new law of the sea.” In an international legal order where access to a judge or an arbitrator requires the consent of both parties to …

Unsupervised Machine Learning Using K-Means Identifies Radiomic Subgroups Of Pediatric Low-Grade Gliomas That Correlate With Key Molecular Markers, Debanjan Haldar, Anahita Fathi Kazerooni, Sherjeel Arif, Ariana Familiar, Rachel Madhogarhia, Nastaran Khalili, Sina Bagheri, Hannah Anderson, Ibraheem Salman Shaikh, Aria Mahtabfar, Meen Chul Kim, Wenxin Tu, Jefferey Ware, Arastoo Vossough, Christos Davatzikos, Phillip B Storm, Adam Resnick, Ali Nabavizadeh

Department of Neurosurgery Faculty Papers

Introduction: Despite advancements in molecular and histopathologic characterization of pediatric low-grade gliomas (pLGGs), there remains significant phenotypic heterogeneity among tumors with similar categorizations. We hypothesized that an unsupervised machine learning approach based on radiomic features may reveal distinct pLGG imaging subtypes.

Methods: Multi-parametric MR images (T1 pre- and post-contrast, T2, and T2 FLAIR) from 157 patients with pLGGs were collected and 881 quantitative radiomic features were extracted from tumorous region. Clustering was performed using K-means after applying principal component analysis (PCA) for feature dimensionality reduction. Molecular and demographic data was obtained from the PedCBioportal and compared between imaging subtypes.

Results: …

In Silico Activity And Admet Profiling Of Phytochemicals From Ethiopian Indigenous Aloes Using Pharmacophore Models, Lemessa Etana Bultum, Gemechu Bekele Tolossa, Gwangmin Kim, Ohhyeon Kwon, Doheon Lee

2020-Current year OA Pubs

In silico profiling is used in identification of active compounds and guide rational use of traditional medicines. Previous studies on Ethiopian indigenous aloes focused on documentation of phytochemical compositions and traditional uses. In this study, ADMET and drug-likeness properties of phytochemicals from Ethiopian indigenous aloes were evaluated, and pharmacophore-based profiling was done using Discovery Studio to predict therapeutic targets. The targets were examined using KEGG pathway, gene ontology and network analysis. Using random-walk with restart algorithm, network propagation was performed in CODA network to find diseases associated with the targets. As a result, 82 human targets were predicted and found …

Trem2 Dependent And Independent Functions Of Microglia In Alzheimer's Disease, Jinchao Hou, Yun Chen, Gary Grajales-Reyes, Marco Colonna

2020-Current year OA Pubs

Microglia are central players in brain innate immunity and have been the subject of extensive research in Alzheimer's disease (AD). In this review, we aim to summarize the genetic and functional discoveries that have advanced our understanding of microglia reactivity to AD pathology. Given the heightened AD risk posed by rare variants of the microglial triggering receptor expressed on myeloid cells 2 (TREM2), we will focus on the studies addressing the impact of this receptor on microglia responses to amyloid plaques, tauopathy and demyelination pathologies in mouse and human. Finally, we will discuss the implications of recent discoveries on microglia …

Race In J. R. R. Tolkien’S The Lord Of The Rings And In Katherine Addison’S The Goblin Emperor, Robin A. Reid Dr.

Journal of Tolkien Research

Recent scholarship on how Tolkien's Orcs influenced popular fantasy agrees upon the spread of racist clichés and stereotypes. Dieter Petzold, in "'Oo, Those Awful Orcs!': Tolkien's Villains as Protagonists in Recent Fantasy Novels," analyzes how four novels attempt but fail to present orcs as focal and sympathetic characters. In Race and Popular Fantasy Literature, Helen Young argues that the influence Tolkien's Orcs had on fantasy literature, film, and games is that of structural racism in which "race [is] the conventional framework around which difference is built " (35). She acknowledges that critical reading of Tolkien's works can "provide background …

Realizing Molecular Machine Learning Through Communications For Biological Ai: Future Directions And Challenges, Sasitharan Balasubramaniam, Samitha Somathilaka, Sehee Sun, Adrian Ratwatte, Massimiliano Pierobon

School of Computing: Faculty Publications

Artificial Intelligence (AI) and Machine Learning (ML) are weaving their way into the fabric of society, where they are playing a crucial role in numerous facets of our lives. As we witness the increased deployment of AI and ML in various types of devices, we benefit from their use into energy-efficient algorithms for low powered devices. In this paper, we investigate a scale and medium that is far smaller than conventional devices as we move towards molecular systems that can be utilized to perform machine learning functions, i.e., Molecular Machine Learning (MML). Fundamental to the operation of MML is the …

Investigation Of Healthcare Providers Beliefs, Confidence, Knowledge, And Prevelance Within Practice Of Medicinal Cannabinoids And The Endocannabinoid System: Pre And Post Educational Intervention, Kelcey O'Daniel

Doctor of Nursing Practice Scholarly Project

The purpose of this scholarly project was to assess healthcare providers’ knowledge, and confidence of the endocannabinoid system, medicinal cannabinoids, and the action of Cannabidiol (CBD) prior to, and after an educational delivery. The surveys and educational intervention were distributed by social media platforms to healthcare providers and students of the qualifying professions to gain insight on current confidence, knowledge, and prevalence when it comes to medicinal cannabinoid discussion within healthcare practice. Results yielded statistically significant results in a multitude of aspects. When running paired samples correlations, each category within the investigation into provider confidence, proved to be statistically significant …

A Tree-Ring Record Of Historical Fire Activity In A Piedmont Longleaf Pine (Pinus Palustris Mill.) Woodland In North Carolina, Usa, Monica T. Rother, Thomas W. Patterson, Paul A. Knapp, Tyler J. Mitchell, Nell Allen

Faculty Publications

CO₂ capture from industrial point source waste streams represents an important need for achieving the global goal of carbon-neutrality. Compared with conventional liquid sorbents, solid sorbents can exhibit several distinct advantages, including enhanced lifetime and reduced energy consumption for sorbent regeneration. Considering that reducing CO₂ emission is a great challenge, reaching approximately 37 billion metric tons just in 2021, ideal sorbent solutions should not only exhibit a high capture performance but also enable large scale manufacturing using low-cost precursors and simple processes. In this work, we demonstrate the use of a commodity polymer, polystyrene-block-polyisoprene-block-polystyrene …

The Potential Of Liquid For Breast Cancer: A Review, Sonar Soni Panigoro, Clarissa Kezia Yuella -

The New Ropanasuri Journal of Surgery

Introduction. Tissue biopsy is the current gold standard for cancer diagnosis, targeted treatment, and prognosis. However, biopsy is an invasive procedure that could result in postoperative bleeding, pain, and infection. Such limitations may now be resolved by the clinical technique known as liquid biopsy, which enables a better representation of disease status.

Method. This literature review was conducted through online databases (PubMed, Ascopubs, EuroPMC) using the following keywords: "liquid biopsy", "ctDNA", "CTC", "breast cancer", "pathogenesis of breast cancer", "tumor microenvironment”, “ctdna detection technologies”, "early diagnosis", "targeted therapy" ,"monitoring disease progression”, and "prognosis”. The literature search was conducted using the PRISMA …

Chemical And Biological Stability Under Forced Degradation And Accelerated Storage Conditions Of The Anti-Acne Formulation Of Pra-Sa-Mang-Khud Ethanolic Extract, Kalyarut Phumlek, Arunporn Itharat, Ubonwan Saesiw, Weerachai Pipatrattanaseree, Krit Piwngam

Asian Medical Journal and Alternative Medicine

Introduction: Pra-Sa-Mang-Khud (PSM) formula is the mixture of Garcinia mangostana pericarp and Ha-Rak remedy developed for acne treatment. However, the chemical and biological stability of PSM extract is necessary for an optimal manufacturing process. Therefore, this study was aimed to investigate the stability of PSM ethanolic extract under forced degradation and accelerated storage conditions.
Methods: Thermal degradation, moisture hydrolysis, acid hydrolysis, alkaline hydrolysis, and oxidation were performed in forced degradation studies. In addition, PSM extract was kept in accelerated storage conditions at 40 ± 2ºC with 75 ± 5% RH for 6 months. Finally, PSM extracts under forced degradation and …

Genotoxic, Antigenotoxic, And Antioxidative Potentials Of Thai Bee Products, Treetip Ratanavalachai, Wantha Jenkhetkan, Chalerm Jansom, Arunporn Itharat, Sumon Thitiorul

Asian Medical Journal and Alternative Medicine

Introduction: Bee products are becoming increasingly used as nutritional supplements. They have been reported to have antibacterial and antitumor properties.

Objective: We aimed to compare the efficacies on antioxidative and antigenotoxic potentials among these products from Chiangmai, northern Thailand, including their genotoxicity.

Methods: The genotoxicity and antigenotoxicity were assessed using in vitro sister chromatid exchange assay in human lymphocytes. Chemical compositions and antioxidative activities were investigated using standard chemical methods.

Results: Our results revealed that the lipid extracts tended to have the least genotoxicity compared to their defatted and crude extracts. The lipid extract of propolis at a nongenotoxic dose …

The Effectiveness Of Mind Map As A Teaching Tool For Medical Students, Sidayu Suriya, Nuntra Suwantarat, Vorawan Vanicharoenchai, Cherdsak Iramaneerat

Asian Medical Journal and Alternative Medicine

Objective: The mind map has been proven for improving learning effectiveness. We hypothesized that the mind map is helpful to enhance learning outcomes by increasing knowledge retention and student perception for 3^rd year medical students at the Faculty of Medicine, Naresuan University.

Methods: A randomized controlled trial study was conducted by comparing the academic performance (MCQs scores for pre-test, immediate post-test, and delayed post-test) and the improvement in academic performance in each group by using the paired t test and the students’ perception survey (Assessing Student Perspective of Engagement in Class Tool, ASPECT) after attending the class of “osteoporosis” …

How Does Allium Leafy Parts Metabolome Differ In Context To Edible Or Inedible Taxa? Case Study In Seven Allium Species As Analyzed Using Ms-Based Metabolomics, Mostafa H. Baky, Samir N. Shamma, Mohamed R. Khalifa, Mohamed A. Farag

Faculty Journal Articles

Genus Allium (F. Amaryllidaceae) includes a wide variety of edible foods widely consumed for their nutritive as well as health benefits. Seven Allium species, viz., chives, Egyptian leek, French leek, red garlic, white garlic, red onion, and white onion aerial parts were assessed for metabolome heterogeneity targeting both aroma and nutrients phytochemicals. A headspace solid-phase microextraction (HS-SPME) and gas chromatography-mass spectrometry (GC-MS) were employed. Results revealed extensive variation in volatiles and nutrients profile among the seven Allium species represented by a total of 77 nutrients and 148 volatiles. Among edible Allium species, French leek encompassed high levels of nutrients, viz., …