Digital Commons Network^™

Synthetic Microplastic Abundance And Composition Along A Longitudinal Gradient Traversing The Subtropical Gyre In The North Atlantic Ocean, Winnie Courtene-Jones, Simon Van Gennip, Juliette Penicaud, Emily Penn, Richard C. Thompson

School of Biological and Marine Sciences

Plastic pollution has been reported in the North Atlantic Ocean since the 1970s, yet limited data over subsequent decades pose challenges when assessing spatio-temporal trends in relation to global leakages and intervention strategies. This study quantified microplastics within the upper ocean along a longitudinal transect of the North Atlantic and its subtropical gyre. Microplastics were sampled from surface and subsurface (−25 m) water using a manta trawl and NIKSIN bottle respectively. The surface water polymer community varied significantly between geographic positions (‘inshore’, ‘gyre’, ‘open ocean’), and was significantly influenced by fragment quantity. Compared to other positions, the North Atlantic gyre …

Long‐Term Effects Of Artificial Nighttime Lighting And Trophic Complexity On Plant Biomass And Foliar Carbon And Nitrogen In A Grassland Community, Vinka Anic, Kevin J. Gaston, Thomas W. Davies, Jonathan Bennie

School of Biological and Marine Sciences

No abstract provided.

A Nation That Rebuilds Its Soils Rebuild Itself- An Engineer's Perspective, Karen L. Johnson, Neil D. Gray, Wendy Stone, Bryce F.J. Kelly, Mark F. Fitzsimons, Cathy Clarke, Lynsay Blake, Stephen Chivasa, Florence Mtambanengwe, Paul Mapfumo, Andy Baker, Sabrina Beckmann, Lena Dominelli, Andrew L. Neal, Tariro Gwandu

School of Geography, Earth and Environmental Sciences

Nations can build and rebuild degraded soils to help address climate change and potentially improve the nutritional content of food if we change policies that allow the addition of safe mineral and organic wastes to soil. We present a framework that facilitates the transition from intensive conventional to more regenerative farming practices by considering soil’s natural cycle. Our paper is presented in three parts. Firstly, we consider that ’soil is living’; just like humans, the soil biome needs a balanced diet of macro and micronutrients as well as a nurturing environment. We simplify the soil science and take a systems …

Ocean Connectedness And Consumer Responses To Single-Use Packaging, Sohvi Nuojua, Sabine Pahl, Richard Thompson

School of Biological and Marine Sciences

Single-use packaging items constitute a large proportion of the plastic litter found in the marine environment. Consumer decisions contribute to the accumulation of this pollution in the environment. Here we undertook two studies to assess consumer responses to different types of single-use packaging. Moreover, we introduce a new measure of ocean connectedness adapted from nature connectedness measures and investigate its association with consumer response. In Study 1, 60 UK undergraduate students completed a packaging rating task and a survey on ocean connectedness in a laboratory environment. In the rating task pictures of bottled drinks with unique combinations of packaging recyclability …

The Bi-Partisan Enabling Of Presidential Power: A Review Of David Driesen's The Specter Of Dictatorship: Judicial Enabling Of Presidential Power (2021), Jed Handelsman Shugerman

Faculty Scholarship

In "The Specter of Dictatorship: Judicial Enabling of Presidential Power," David Driesen questions the unitary executive theory and other doctrines of unchecked executive power. He offers primarily a critique of purposivism, a mix of original public meaning and more recent history illuminating those purposes: the Founders’ anti-tyranny purpose and then the rise of European tyranny from Nazi Germany to contemporary Hungary, Turkey, and Poland.
/="/">
/="/">This review first focuses on Driesen’s approach to Congress: He identifies the broad congressional delegation of powers to the president as a source of expansive executive power, but he does not entertain that doctrines …

Protecting International Travelers During The Pandemic: Charting The Way Forward, Fernando Dias Simoes

Minnesota Journal of International Law, Vols. 28:2 onward (2019-present)

No abstract provided.

Promoting Vaccine Innovation, Ana Santos Rutschman, Mirit Eyal-Cohen

Faculty Publications

As society grows to understand the need to promote innovation, policymakers try to employ an arsenal of policy tools, from traditional intellectual property (“IP”) to newer tools such as grants, regulatory vouchers, and prizes. This Article argues that these frameworks crowd out certain types of investments in innovation projects that have a high social value. Vaccine innovation is a case in point. Despite the immense socioeconomic benefit of vaccines, existing policies have been limited in fostering investments in this space. This is because they fail to directly address the relevant bottleneck issues distinct to vaccine development.

This Article offers a …

Viral Sovereignty,Vaccine Diplomacy,And Vaccine Nationalism: The Institutions Of Global Vaccine Access, Sam F. Halabi, Ana Santos Rutschman

Faculty Publications

The COVID-19 pandemic has triggered a global vaccine race. Distributive questions about which countries will receive scarce doses and under which conditions pervade international law and diplomacy. This Article is the first to describe the phenomena that have driven the development of international vaccine-sharing mechanisms, identify the international organizational forces that explain the phenomena, and explain how international organizations may facilitate international cooperation before, during, and after global crises.

This Article explores the longstanding dissociation between global public health imperatives and nationalist responses to pandemics within the frameworks of “vaccine nationalism,” “viral sovereignty,” and “vaccine diplomacy.” The Article then considers …

In Situ Vaccination Using Plant Viral Particles As A Novel Approach For Cancer Immunotherapy, Chenkai Mao

Dartmouth College Ph.D Dissertations

Non-infectious to mammals, genetically, and physically stable plant virus-based nanoparticles have been increasingly studied as a novel platform for cancer vaccine and adjuvants due to their immunogenic properties. Our prior work showed that, empty cowpea mosaic virus (eCPMV), a plant virus-like particle (VLP) that is composed of a separated capsid, is an excellent in situ vaccine (ISV) for cancer immunotherapy; however, little is known about the mechanisms linked to their activities regarding recognition and antigen presentation.

In the present studies, we report cowpea mosaic virus (CPMV) and RNA-lacking CPMV (empty, eCPMV) are both toll like receptor (TLR) agonists for TLRs …

The Three-Way Interplay Among Early Life Exposures, The Gut Microbiome, And Outcomes In Infancy, Yuka Moroishi

Dartmouth College Ph.D Dissertations

The bidirectional relationship between the gut microbiome and immune system plays an important role in host immune status: the immune system provides the gut microbiome the optimal environment to thrive in, and the gut microbiome helps regulate the immune system. This relationship is especially important in infants, whose immune system is still premature and rely on innate immunity.

We investigated the three-way interplay among early-life exposures, the developing gut microbiome, and outcomes in infancy from the general population in New Hampshire, US. We used prospective cohort data from the New Hampshire Birth Cohort study to 1) determine whether timing of …

The Design Of Cmos Front-End Amplifiers For Electrical Impedance Applications, Yueh-Ching Teng

Dartmouth College Ph.D Dissertations

Electrical Impedance Tomography (EIT) is a medical imaging methodology that does not need any kind of ionizing radiation. It is significantly cheaper and smaller than Computerized Tomography (CT) or Magnetic Resonance Imaging (MRI). These advantages make EIT particularly suitable for emerging applications like the continuous medical imaging and telemonitoring of organ function. Current bench-top EIT systems are bulky and require shielded cables to interface with measurement electrodes. The cable introduces parasitic capacitances which shunt the desired signals and degrade the accuracy of the measurements. A EIT system based on application-specific integrated circuits (ASICs) can reduce the parasitic and stray capacitance …

Advancing Combined Radiological And Optical Scanning For Breast-Conserving Surgery Margin Guidance, Samuel Stewart Streeter

Dartmouth College Ph.D Dissertations

Breast cancer is one of the most common types of cancer worldwide, and standard-of-care for early-stage disease typically involves a lumpectomy or breast-conserving surgery (BCS). BCS involves the local resection of cancerous tissue, while sparring as much healthy tissue as possible. State-of-the-art methods for intraoperatively evaluating BCS margins are limited. Approximately 20% of BCS cases result in a tissue resection with cancer at or near the resection surface (i.e., a positive margin). A two-fold increase in ipsilateral breast cancer recurrence is associated with the presence of one or more positive margins. Consequently, positive margins often necessitate costly re-excision procedures to …

Investigating Environmetal Justice Education In Rural, Title 1 Stem Classrooms, Luis Prado

Research Papers

No abstract provided.

First Comes Love. Then Comes Marriage. Then Comes A Baby In A Baby Carriage: An Application Of Protective Surrogacy Laws To The Tarheel State, Justin Lo

Seattle University Law Review

Assisted Reproductive Technology (ART) and determining parentage have a common feature: each is governed by state law or the lack of such laws. This lack of statutory regulations presents significant legal challenges to gay men who wish to start a family. Because same-sex male couples seeking to become fathers through ART and surrogacy are the most likely demographic to be impacted when determining parentage, laws that influence the direction of surrogacy will undeniably facilitate whether both males will be deemed a father. To provide same-sex male couples with a pathway to parenthood, North Carolina should (1) develop robust, protective surrogacy …

Race In Washington’S Juvenile Legal System: 2021 Report To The Washington Supreme Court, Task Force 2.0 Juvenile Justice Subcommittee

Seattle University Law Review

Part I of this report provides the core work of the subcommittee and is intended to function as a stand-alone document, expressed in youth- friendly language, that sets forth: (1) the youth-articulated goals for systemic change to the juvenile legal system; (2) a narrative of how the system currently works and the harms caused; and (3) the change needed to bring about the youth-articulated goals for systemic change. This document is intended to be a youth-centered blueprint for change—a tool for community advocates, a framework for policy makers, and a call-in to the many institutional actors to center the leadership …

Implementation Of A Tactical Dispatcher Team: The Critical Incident Support System, Kaitlin Durband

Research Papers

A Tactical Dispatch Team is comprised of highly skilled and trained 911 telecommunicators with experience in police, fire, and EMS dispatching. Tactical Dispatch Team members will participate in various training courses and in real-life staged scenarios. Tactical Dispatchers know what and when to document vital information and what data could later be needed in court (Tactical Dispatcher, n.d.). Any incident can turn from calm and simple to chaotic and complex. The Tactical Dispatch Team is a major support system for first responder personnel.

A Missing Narrative: The Creation Of A Trauma-Informed Children’S Book For Children In The Foster Care System, Elizabeth Hoff Saunderson

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

This article includes a review of literature relevant to the experiences of children in the foster care system including demographics, trauma and stressful experiences, attachment challenges, and useful interventions. Limited research has been conducted to inform resource tools for children in foster care. The aim of the present study was to create a trauma-informed resource tool for children in the foster care system in the form of a children’s book. A review of children’s books related to foster care yielded four major themes including the importance of mindful language, the need for a resource tool, a focus on safety, and …

A Mixed-Methods Protocol To Develop And Validate A Stewardship Maturity Matrix For Human Genomic Data In The Cloud, Vasiliki Rahimzadeh, Ge Peng, Mildred Cho

Center for Medical Ethics and Health Policy Staff Publications

This article describes a mixed-methods protocol to develop and test the implementation of a stewardship maturity matrix (SMM) for repositories which govern access to human genomic data in the cloud. It is anticipated that the cloud will host most human genomic and related health datasets generated as part of publicly funded research in the coming years. However, repository managers lack practical tools for identifying what stewardship outcomes matter most to key stakeholders as well as how to track progress on their stewardship goals over time. In this article we describe a protocol that combines Delphi survey methods with SMM modeling …

Interest-Based Incorporation: Statutory Realism Exploring Federalism, Delegation, And Democratic Design, Sheldon Evans

Scholarship@WashULaw

Statutory interpretation is a unique legal field that appreciates fiction as much as fact. For years, judges and scholars have acknowledged that canons of interpretation are often based on erudite assumptions of how Congress drafts federal statutes. But a recent surge in legal realism has shown just how erroneous many of these assumptions are. Scholars have created a robust study of congressional practices that challenge many formalist canons of interpretation that are divorced from how Congress thinks about, drafts, and enacts federal statutes. This conversation, however, has yet to confront statutory incorporation, which describes when Congress incorporates state law into …

Sr. Ciencia And El Mago: A Legacy Of Archaeological Discovery And Lifelong Learning, Michael T. Searcy

Faculty Publications

As partners in the pursuit of archaeological discovery, Paul Minnis and Michael Whalen developed an enduring professional relationship that resulted in productive careers marked by multiple field projects and numerous scholarly publications. While engaged in academic archaeology, they also fostered a new generation of archaeologists along the way. An integral part of their pedagogy was carried out in the field where students worked alongside Mike and Paul, learning not only how to carry out an archaeological project from beginning to end, but also how to collaborate in a field of study that has become increasingly interdisciplinary. This paper presents my …

Organizational Perspectives On Outdoor Talking Therapy: Towards A Position Of ‘Environmental Safe Uncertainty’, Sam J. Cooley, Ceri R. Jones, Duncan Moss, Noelle Robertson

School of Psychology

No abstract provided.

Coastal Dune Dynamics In Embayed Settings With Sea-Level Rise – Examples From The Exposed And Macrotidal North Coast Of Sw England, Gerd Masselink, Sue Brooks, Tim Poate, Christopher Stokes, Tim Scott

School of Biological and Marine Sciences

Coastal dune systems are natural forms of coastal defence, but are expected to exhibit increased erosion rates due to climate change impacts, notably sea-level rise and, potentially, increased storminess. This is especially the case in embayed coastal settings, i.e., where there are no significant sediment inputs into the beach/dune system from longshore sources. Dune development is closely linked to that of beaches that lie seaward, but their temporal dynamics tend to be asynchronous. So, whereas beaches are generally highly variable over a short- to medium-term (event–decadal) time scales, potentially obscuring a longer-term (decadal–centennial) sea-level signal, dunes display a low-pass filtered …

Assessing The State Of Marine Biodiversity In The Northeast Atlantic, A. Mcquatters-Gollop, L. Guérin, N. L. Arroyo, A. Aubert, L. F. Artigas, J. Bedford, E. Corcoran, V. Dierschke, S. A.M. Elliott, S. C.V. Geelhoed, A. Gilles, J. M. González-Irusta, J. Haelters, M. Johansen, Loc'h F Le, C. P. Lynam, N. Niquil, B. Meakins, I. Mitchell, B. Padegimas, R. Pesch, I. Preciado, I. Rombouts, G. Safi, P. Schmitt, U. Schückel, A. Serrano, P. Stebbing, La Torriente A De, C. Vina-Herbon

School of Biological and Marine Sciences

The Northeast Atlantic, a highly productive maritime area, has been exposed to a wide range of direct human pressures, such as fishing, shipping, coastal development, pollution, and non-indigenous species (NIS) introductions, in addition to anthropogenically-driven global climate change. Nonetheless, this regional sea supports a high diversity of species and habitats, whose functioning provides a variety of ecosystem services, essential for human welfare. In 2017, OSPAR, the Northeast Atlantic Regional Seas Commission, delivered an assessment of marine biodiversity for the Northeast Atlantic. This assessment examined biodiversity indicators separately to identify changes in Northeast Atlantic biodiversity, but stopped short of determining the …

Introducing Undergraduates To Instructional Design In A Graduate Studio: An Experiential, Model-Centered Approach, Rebecca Stull Zundell, William Sowards, Scott L. Howell, Jason K. Mcdonald

Faculty Publications

This case study describes a combined graduate and undergraduate instructional design studio that introduced undergraduate students to instructional design in a multifaceted, holistic, and applied way. Reviewing the experience of the undergraduates in the course, this design case describes four learning interventions used to create this applied experience: (1) instructional design team projects—one non-profit and the other in higher education, (2) weekly seminars and biweekly training sessions from field experts, (3) an experiential out-of-state trip, and (4) weekly reflection journals. These studio-based learning interventions are presented within the context of the Experiential Learning Theory and Model-Centered Instruction. Overall, the course …

Macroarchaeology, Epistomology, And The Quality Of The Archaeological Record, James R. Allison

Faculty Publications

Perrault (2019) combines a critique of current archaeological practice with a call to re-center research on questions of culture history as well as “macroarchaeology”, or the search for large-scale patterns of human behavior and cultural development. His arguments for what archaeologists should do (and stop doing) are driven by the way the quality of the archaeological record underdetermines the answers to questions that archaeologists often seek to answer. There is much to like in Perrault’s arguments, but there also are some problematic aspects. I agree that something like Perrault’s macroarchaeology should receive greater focus within the discipline, and that archaeologists …

Final Thoughts And Observations, James R. Allison, Heidi Roberts, Jerry D. Spangler

Faculty Publications

This chapter addresses three topics inspired by the discoveries made during Jackson Flat’s archaeological investigations. The first topic examines the implications of the discovery of early maize agriculture in the Far Western region. Our data suggest that the Far Western Basketmaker tradition developed on a trajectory separate from the Western Basketmaker groups associated with the White Dog Phase in the Four Corners region.

Foundations Of Online Learning: Challenges And Opportunities, Christine Greenhow, Charles R. Graham, Matthew J. Koehler

Faculty Publications

Online learning—learning that involves interactions that are mediated through using digital, typically internet-based, technology—is pervasive, multi-faceted, and evolving, creating opportunities and challenges for educational research in the wake of the COVID-19 pandemic. In this special issue, we advance an interdisciplinary agenda for online learning research at the intersection of educational technology, educational psychology, and the learning sciences. In this first article in the issue, we define online learning including its variants, review historical and current contexts, explore its multidimensionality, and assert key issues shaping contemporary online learning. We propose five important lenses: community, engagement, pedagogy, equity, and design-based research, through …

Past, Present And Future Of Conservative Oxygen Therapy In Critical Care, Daniel Martin, David Harrison, Paul Mouncey, B. Ronan O'Driscoll, Mike Grocott, Lorna Miller, Doug Gould, Alvin Richards-Belle, Kathryn Rowan

Peninsula Medical School

Conservative oxygen therapy (COT) is the administration lower levels of supplemental oxygen than usual in order to tolerate a lower level of arterial oxygenation (either the partial pressure (PaO2) or haemoglobin saturation (SaO2)) than normal. Its purpose is to reduce a patient’s overall exposure to additional oxygen in order to minimise the risk of oxyen toxicity.1 This approach to oxygen therapy has also been called permissive hypoxaemia (PH) and the terms are frequently used interchangeably; here, we refer to all efforts to reduce supplemental oxygen administration or arterial oxygenation as COT. Studies have been conducted across a wide range of …

Opicapone In Uk Clinical Practice: Effectiveness, Safety And Cost Analysis In Patients With Parkinson's Disease, Christine Schofield, K. Ray Chaudhuri, Camille Carroll, Jagdish C. Sharma, Nicola Pavese, Jonathan Evans, Thomas Foltynie, Heinz Reichmann, Laura Zurowska, Patrício Soares-Da-Silva, Andrew Lees

Peninsula Medical School

Aim: This subanalysis of the OPTIPARK study aimed to confirm the effectiveness and safety of opicapone in patients with Parkinson's disease and motor fluctuations in clinical practice specifically in the UK and to assess the impact of opicapone on treatment costs. Methods: Patients received opicapone added to levodopa for 6 months. Clinical outcomes were assessed at 3 and 6 months and treatment costs at 6 months. Results: Most patients' general condition improved at 3 months, with sustained improvements reported at 6 months. Opicapone improved motor and non-motor symptoms at both timepoints, was generally well tolerated and reduced total treatment costs …

What Matters Most To Adults With A Tracheostomy In Icu And The Implications For Clinical Practice: A Qualitative Systematic Review And Metasynthesis, Helen Newman, Gemma Clunie, Sarah Wallace, Christina Smith, Daniel Martin, Natalie Pattison

Peninsula Medical School

Purpose Tracheostomy is a common surgical procedure in ICU. Whilst often life-saving, it can have important impacts on patients. Much of the literature on tracheostomy focuses on timing and technique of insertion, risk factors and complications. More knowledge of patient experience of tracheostomy in ICU is needed to support person-centred care. Materials and methods Qualitative systematic review and metasynthesis of the literature on adult experience of tracheostomy in ICU. Comprehensive search of four bibliographic databases and grey literature. Title and abstract screening and full text eligibility was completed independently by two reviewers. Metasynthesis was achieved using thematic synthesis, supported by …