Digital Commons Network^™

Presence, Sources And Transport Of Polycyclic Aromatic Hydrocarbons In The Arctic Ocean, Lihong Zhang, Yuxin Ma, Simon Vojta, Maya Morales-Mcdevitt, Mario Hopggmann, Thomas Soltwedel, Jane Kirk, Amila De Silva, Derek Muir, Rainer Lohmann

Graduate School of Oceanography Faculty Publications

Polycyclic aromatic hydrocarbons (PAHs) are continuously released from multiple sources and are prone to long-range transport. Little is known regarding their presence, transport and fate in remote and deep oceans. Polyethylene passive samplers were hence deployed at deep moorings and surface seawater in the Fram Strait and Canadian Archipelago, as well as in air and surface water of the lower Great Lakes, a potential high-emission region, to understand the transport of PAHs to the Arctic. Dissolved PAHs showed significantly higher concentrations in the lower Great Lakes than those in the high Arctic. Concentrations of dissolved PAHs (Σ₁₉PAHs) ranged …

Editorial: Symbiotic Relationships As Shapers Of Biodiversity, Guillaume Chomicki, Roxanne A. Beinart, Carlos Prada, Kimberly B. Ritchie, Marjorie Gail Weber

Graduate School of Oceanography Faculty Publications

No abstract provided.

Global 16s Rrna Diversity Of Provannid Snail Endosymbionts From Indo-Pacific Deep-Sea Hydrothermal Vents, Corinna Breusing, Jade Castel, Yi Yang, Thomas Broquet, Jin Sun, Didier Jollivet, Pei-Yuan Qian, Roxanne A. Beinart

Graduate School of Oceanography Faculty Publications

No abstract provided.

Pfas And Precursor Bioaccumulation In Freshwater Recreational Fish: Implications For Fish Advisories, Heidi M. Pickard, Bridger J. Ruyle, Colin P. Thackray, Adela Chovancova, Clifton Dassuncao, Jitka Becanova, Simon Vojta, Rainer Lohmann, Elsie M. Sunderland

Graduate School of Oceanography Faculty Publications

Per- and polyfluoroalkyl substances (PFAS) are a diverse class of fluorinated anthropogenic chemicals that include perfluoroalkyl acids (PFAA), which are widely used in modern commerce. Many products and environmental samples contain abundant precursors that can degrade into terminal PFAA associated with adverse health effects. Fish consumption is an important dietary exposure source for PFAS that bioaccumulate in food webs. However, little is known about bioaccumulation of PFAA precursors. Here, we identify and quantify PFAS in recreational fish species collected from surface waters across New Hampshire, US, using a toolbox of analytical methods. Targeted analysis of paired water and tissue samples …

Strength And Consistency Of Density Dependence In Marine Fish Productivity, Anna Rindorf, Mikael Van Deurs, Daniel Howell, Elder Andonegi, Aaron Berger, Bjarte Bogstad, Noel Cadigan, Bjarki Þór Elvarsson, Niels Hintzen, Marie Savina Roland, Marc Taylor, Vanessa Trijoulet, Tobias Van Kooten, Fan Zhang, Jeremy Collie

Graduate School of Oceanography Faculty Publications

The correct prediction of the shape and strength of density dependence in productivity is key to predicting future stock development and providing the best possible long-term fisheries management advice. Here, we identify unbiased estimators of the relationship between somatic growth, recruitment and density, and apply these to 80 stocks in the Northeast Atlantic. The analyses revealed density-dependent recruitment in 68% of the stocks. Excluding pelagic stocks exhibiting significant trends in spawning stock biomass, the probability of significant density dependence was even higher at 78%. The relationships demonstrated that at the commonly used biomass limit of 0.2 times maximum spawning stock …

Global Distribution Of The Cold-Water Coral Lophelia Pertusa, R. Tong, Andrew J. Davies, A. Purser, X. Liu, F. Liu

Graduate School of Oceanography Faculty Publications

Lophelia pertusa plays an important role as a major contributor to many cold-water coral reefs, supporting a high diversity of associated benthic and benthopelagic species. Due to the high sensitivity of L. pertusa to human activity, it has been classified as indicator species for Vulnerable Marine Ecosystems. However, the global spatial distribution of L. pertusa is far from well known. In this study, a database of L. pertusa presence data was compiled derived from the large number of L. pertusa occurrence records appearing in recent years. In conjunction with data layers covering a range of environmental drivers, habitat suitability for …

Reflector Magazine, Georgia Southern University

Reflector Magazine

• Letters from the Editors
• Jessica Baytea
• Kaz Thomas Defining Non-Binary
• The Female Gaze
• 100th Edition Photoshoot
• Men Embrace Femininity
• Ode to Nail Polish
• The Power in Expressing Femininity

Novel Approaches To Assess Cellular Interactions And Their Role In The Pathology And Treatment Of Lymphoproliferative Disorders, Frances Hilary Rose Frend

Other Faculty of Health Theses

Background: Migration and homing are essential to B-lymphocyte mediated immunity, and are driven by rapid, directed, and appropriate reorganisation of the actin cytoskeleton. Important observations have linked the cytoskeletal-rearrangements made by leukaemic B-lymphocytes of chronic lymphocytic leukaemia (CLL) to disease pathology. In particular, cytoskeletal alterations mediated by B-cell receptor (BCR) engagement or chemokine-binding are recognised to be central to the migration of CLL cells to lymphoid tissues, where they engage in the complex cellular and molecular interactions that underlie their survival, proliferation, and drug resistance. Further emphasising this importance, has been the observation that highly effective small molecule inhibitors that …

Nitrite And Insulin Lower The Oxygen Cost Of Atp Synthesis In Skeletal Muscle Cells By Pleiotropic Stimulation Of Glycolysis, Rosie Donnell

Other Faculty of Health Theses

Dietary nitrate lowers the oxygen cost of submaximal exercise, but precise mechanistic insight into how this occurs is lacking. Research suggests that dietary nitrate may render oxidative ATP synthesis more efficient, but evidence is inconclusive at present. This thesis aimed to establish how nitrite (a reduced form of nitrate) affects the bioenergetics of cultured skeletal muscle cells. Comparison between the acute effects of nitrite and insulin, a hormonal regulator of muscle function that increases mitochondrial efficiency, was explored to assess possible mechanistic overlap. Calculation of real-time intracellular ATP synthesis rates from simultaneous oxygen consumption and medium acidification measurements revealed the …

Prediction Of Cardiometabolic Risk In Children, Olubukola Ajala

Other Faculty of Health Theses

Background: Three decades of clinical research have demonstrated that the risks of atherosclerotic cardiovascular disease (ACVD: coronary disease and ischaemic stroke), and the closely related type 2 diabetes (T2D) are established and influenced by events during childhood. This is at least partly because childhood obesity usually leads to adult adiposity; so, the currently high prevalence of adult cardiometabolic disease, means that obesity needs to be identified as early as possible, ideally in childhood. Screening for obesity largely relies on anthropometric measurements like body mass index (BMI), however this has many limitations including its inability to distinguish lean from fat mass. …

Architectural Design For Dementia: Exploring Alternate Contemporary Cultures Of Residential Care Design, Ricky Burke

School of Art, Design and Architecture Theses

Architectural Design for Dementia: exploring alternate contemporary cultures of residential care design. The Alzheimer's Association (2018) projected the number of people living with a dementia diagnosis to surpass 2 million, reaching 1 in 37.5 of the population of the United Kingdom by 2051: up from 1 in 79 in 2015. This growth in rate and number coincides with an ageing population and a decline in the relative number of people able to care for the needs of people suffering difficulties associated with the symptoms of their diagnosis. The move to a residential care home is not only a viable but …

An Interdisciplinary Study Of An Aesthetic Particularism: The ‘Split Representation In The Art Of Asia And America’, Benjamin Pothier

School of Art, Design and Architecture Theses

An interdisciplinary study of an aesthetic particularism: the ‘Split representation in the Art of Asia and America’. This thesis consists of an interdisciplinary research on an aesthetic particularism mentioned by anthropologist Claude Levi-Strauss as “The split representation in the Art of Asia and America” in his 1944 eponymous essay. Most researchers include in this group the Ainu and Jōmon People from Japan, tribes from the Amur Basin, Haida people from the Northern West Coast, Ancient China (Yangshao and Shang Dynasty), Māori People from New Zealand and Kadiweu people from Brazil. I conducted this inquiry through an online study of academic …

Association Between Hispanic Parents’ Attitudes And Knowledge Regarding Obesity And Their Children’S Body Mass Index, Renee Starr, Eva Miller, Roy K. Chen, Ralph Carlson, Veronica I. Umeasiegbu, Bruce J. Reed

School of Rehabilitation Services & Counseling Faculty Publications

According to the Centers for Disease Control and Prevention, more than 13.7 million children experience obesity nationally and Hispanic children display the highest occurrences of obesity for all racial/ethnic groups (Hales et al., 2020). Because parents have a significant influence on their children’s overall health, we were interested in examining whether parents’ attitudes and knowledge about obesity impacted their child’s body mass index (BMI) for their age. We surveyed 210 adult Hispanic parents whose children were receiving general healthcare services at a pediatric medical clinic located near the U.S.-Mexico border. A multiple regression analysis was conducted to evaluate the estimation …

Predictive Effects Of Satisfaction With Life, Self-Esteem, And Loneliness On Alcohol Related Problems In College Students At A Minority-Serving Institution, Roy K. Chen, Wei-Mo Tu, Rebecca R. Sametz, Bryan S. Austin

School of Rehabilitation Services & Counseling Faculty Publications

Objective: Little research has focused on the drinking issues at minority serving institutions. The purpose of this study was to examine the relationships among personal psychological distress, mental well-being, self-esteem, and alcohol-related problems. Participants: 360 undergraduate students were recruited at a public university in the Southwest US. Methods: A cross-sectional design survey was conducted. One-way ANOVA and multiple regression analyses were utilized. Results: Male students experienced more alcohol-related problems than female students. Statistically significant correlations were found among life satisfaction and loneliness, life satisfaction and self-esteem, life satisfaction and alcohol-related problems, and self-esteem and loneliness. The predictor variables accounted for …

Molecular Control Of The Migratory Phase During Cutaneous Wound Healing, Chloe Elizabeth Bolton

Other Faculty of Health Theses

Superficial cutaneous injuries occur on a huge scale across the globe; while most will resolve without intervention or any lasting damage, many will experience complications that arise through delayed healing or as a consequence of the skins protective barrier being breached. The migration of cutaneous cells across a wound site is a crucial factor in establishing permanent restoration of the skins integrity. This study provides insight into molecular events that facilitate the migratory ability of cutaneous cells during this phase of the healing process. Through subcellular analysis, molecular manipulation and various imaging techniques of in vivo and in vitro wound …

Avoiding Kidney Damage In Icu Sedation With Sevoflurane: Use Isoflurane Instead, J. Robert Sneyd

More Faculty of Health Research

Intensive care unit (ICU) sedation with sevoflurane is associated with nephrogenic diabetes insipidus. Given that isoflurane is now licenced (in Europe) for ICU sedation and has Investigational New Drug status in the USA, evidence indicates that clinicians should stop using sevoflurane in this indication except in the context of clinical trials.

Hypotension During Propofol Sedation For Colonoscopy: A Retrospective Exploratory Analysis And Meta-Analysis, J. Robert Sneyd, Anthony R. Absalom, Clemens R.M. Barends, Jordan B. Jones

More Faculty of Health Research

Background: Intraoperative and postoperative hypotension occur commonly and are associated with organ injury and poor outcomes. Changes in arterial blood pressure (BP) during procedural sedation are not well described. Methods: Individual patient data from five trials of propofol sedation for colonoscopy and a clinical database were pooled and explored with logistic and linear regression. A literature search and focused meta-analysis compared the incidence of hypotension with propofol and alternative forms of procedural sedation. Hypotensive episodes were characterised by the original authors' definitions (typically systolic BP <90 mm Hg). Results: In pooled individual patient data (n=939), 36% of procedures were associated with episodes of hypotension. Longer periods of propofol sedation and larger propofol doses were associated with longer-lasting and more-profound hypotension. Amongst 380 patients for whom individual BP measurements were available, 107 (28%) experienced systolic BP <90 mm Hg for >5 min, and in 89 (23%) the episodes exceeded 10 min. Meta-analysis of 18 RCTs …

Using Microbial Volatile Organic Compounds As Biomarkers Of Occupational Exposure To Mould: A Feasibility Study, Badr El Aroussi, Geneviève Marchand, Simon Aubin, Michèle Bouchard, Sami Haddad

États de la question, rapports d’expertise et revues de littérature

La problématique de la qualité de l’air est un aspect important de la santé et de la sécurité au travail. Les moisissures et leurs composés sont des contaminants auxquels les travailleurs peuvent être exposés. Ces microorganismes sont responsables de nombreux problèmes de santé (maladies ou inconforts), incluant des allergies aiguës, de l’asthme, des sinusites/rhinites, des céphalées, de l’hypersensibilité environnementale, des irritations et des inflammations.

La surveillance classique de la présence fongique se base sur des méthodes d’évaluation directe de la flore mycologique ou sur l’exploitation de la méthode PCR quantitative. Ces approches requièrent néanmoins le recours à une procédure minutieuse …

Interpretable Design Of Reservoir Computing Networks Using Realization Theory, Wei Miao, Vignesh Narayanan, Jr-Shin Li

Publications

The reservoir computing networks (RCNs) have been successfully employed as a tool in learning and complex decision-making tasks. Despite their efficiency and low training cost, practical applications of RCNs rely heavily on empirical design. In this article, we develop an algorithm to design RCNs using the realization theory of linear dynamical systems. In particular, we introduce the notion of α-stable realization and provide an efficient approach to prune the size of a linear RCN without deteriorating the training accuracy. Furthermore, we derive a necessary and sufficient condition on the irreducibility of the number of hidden nodes in linear RCNs based …

Navigating Midwifery Solidarity: A Feminist Participatory Action Research Framework, Kate Buchanan, Elizabeth Newnham, Sadie Geraghty, Lisa Whitehead

Nursing Papers and Journal Articles

Background: A core aspect of midwifery philosophy is the optimisation of normal physiology; however, this has been challenged as a radical idea in the medicalisation of birth. Research has demonstrated the benefits of midwifery in improving outcomes for both mothers and babies. The understanding of midwifery benefits fails to reach wider sociocultural contexts as births becomes more medicalised. Midwifery research requires an action arm, to help translate theory to practice and mobilise midwives in solidarity with women towards action and change.

Aim: The aim of this article is to describe a Feminist Participatory Action Research (FPAR) by establishing the philosophical …

Grand Challenges In Low Temperature Plasmas, Xinpei Lu, Peter J. Bruggeman, Stephan Reuter, George Naidis, Annemie Bogaerts, Mounir Laroussi, Michael Keidar, Eric Robert, Jean-Michel Pouvesle, Dawei Liu, Kostya (Ken) Ostrikov

Electrical & Computer Engineering Faculty Publications

Low temperature plasmas (LTPs) enable to create a highly reactive environment at near ambient temperatures due to the energetic electrons with typical kinetic energies in the range of 1 to 10 eV (1 eV = 11600K), which are being used in applications ranging from plasma etching of electronic chips and additive manufacturing to plasma-assisted combustion. LTPs are at the core of many advanced technologies. Without LTPs, many of the conveniences of modern society would simply not exist. New applications of LTPs are continuously being proposed. Researchers are facing many grand challenges before these new applications can be translated to practice. …

Morphometric Quantification Of Cockpit Karst In A Jamaican Bauxite Mining Concession, M Sean Chenoweth

Research, Publications & Creative Work

A digital surface model (DSM) is used to characterize the landscape and topical karst landforms within a bauxite mining lease in north central Jamaica. Five case study sites are selected for detailed geomorphic analysis and cartographic visualization using a GIS. In Jamaica, tropical cockpit karst landscapes are composed of several landforms: cockpits, glades, corridors, saddles, and talus slopes. Evidence for the existence and quantification of these landforms is provided in this paper. Study sites have a mean basin area of 96,514 m2 , an average highest elevation of 541 m, mean lowest point of 444 m, with an average enclosed …

Length–Weight Relation For Seven Neotropical Freshwater Fish Species (Actinopterygii) Endemic To Central America, Justin C. Bagley, Maria Florencia Breitman, Jerald B. Johnson

Research, Publications & Creative Work

In the presently reported study, we estimated length–weight relation (LWRs) for seven species of freshwater fishes from Central America. Samples were collected using seines from 60 sites across Nicaragua, Costa Rica, and Panama during field expeditions conducted between 1997 and 2012. The fishes were preserved and transported to the lab, where their total weight (W) was measured (to nearest 0.0001 g) and standard lengths were taken (to nearest 0.01 mm). Data were collected from four livebearers (Poeciliidae), Alfaro cultratus (Regan, 1908), Phallichthys amates (Miller, 1907), Poecilia gillii (Kner, 1863), and Priapichthys annectens (Regan, 1907); the cichlids (Cichlidae), Parachromis dovii (Günther, …

“Someone You Love” Documentary: Using Narratives In Entertainment Media To Increase Hpv Vaccination In Georgia, Gabrielle C. Darville- Sanders, Jann Macinnes, Kelsey Schwarz

Journal of the Georgia Public Health Association

Background: Although HPV is the most common sexually transmitted disease in the United States, vaccination rates are still lagging among adolescents and young adults. Entertainment-education is a popular strategy for incorporating educational messages into entertainment media. With popular shows on television now integrating health messages into their narrative, there are more opportunities to influence knowledge, attitude and health behaviors. Objective: To (a) determine the effectiveness of the HPV narrative included in the “Someone You love” documentary on HPV risk perception, vaccine self-efficacy and behavioral intention for HPV vaccine uptake on college students and (b) assess the immediate impact of the …

Evolution Of Life-History Characteristics In Gadoidei, Joshua Hittie

Master's Theses

Life-history characteristics (e.g., age and growth) have been used extensively to understand the temporal population dynamics of fish species, but less so within a phylogenetic framework. This study investigates life-history characteristics within the suborder Gadoidei (order: Gadiformes) and to test the extent of phylogenetic signal for those characteristics. To accomplish this, a phylogeny of Gadoidei was first constructed based on both mitochondrial and nuclear genes. Within this phylogenetic framework, life-history traits, including growth rate, age at maturity, and longevity, as well as ecological data, such as water depth and diet type, were mapped to the phylogeny using parsimony analysis to …

Queer Church Construction: Dialoguing Ecclesiology And Queer Theory, Daniel Ryne Warwick

Master's Theses

What would “The Church” look like if it were constructed by the socially marginalized, specifically queer bodies (modernity’s LGBTQIA+)? The “Catholic theological tradition” has been reticent in its hesitancy of queer theory, reinforcing the rejection of queer faithful and their highly contextual expressions of spirituality. This thesis seeks to build a well-architected theology out from these rejected queer bodies in order to demonstrate the intrinsically disordered’s inherent ordered-ness within the Catholic tradition and experience. Three distinct pillars of ecclesiology are engaged in this manner: spatiality, temporality, and spirituality. The first chapter, “En-sexed Flesh in De-Sexed Space; or, The Case of …

Phenotypic Analysis Of Murine Gut Associated Lymphocytes, Madison Flood

Master's Theses

γδ T cells are important in the role of immune homeostasis, especially in relation to the gut. It has been shown that there is a higher proportion of γδ T cells in the intestines than in circulation. With this knowledge, our lab focused on understanding the mechanisms of these cells, specifically regarding immune tolerance. In our preliminary research, we identified a subset of γδ T cells that express Foxp3, a transcription factor essential for the functioning of regulatory T cells, in the neonatal (5 day old) intestine. We hypothesized that these Foxp3+ γδ T cells have immunosuppressive functions upon exposure …

Three-Dimensional Staging Series Of Anolis Sagrei, Lilian Epperlein

Master's Theses

With the rapid rise of Evo-devo and the concurrent development of new imaging techniques, comparative studies of development have accelerated over the last decade. Squamates, lizards and snakes, lack a traditional experimental model species for developmental investigations, yet are important for understanding fundamental evolutionary questions because of their remarkable diversity. However, several squamate species have growing communities of biologists building new resources for comparative and experimental studies of lizard development. Creation of detailed embryological atlases for these species will help promote their advancement. In the past, scientists have had to rely on destructive methods to take apart biological samples which …

Bisacodyl Limits Chikungunya Virus In Vitro And Is Broadly Antiviral, Natalie June Lomascolo

Master's Theses

Identifying novel antivirals requires significant time and resource investment, and the continuous threat of viruses to human health necessitates commitment to antiviral identification and development. Developing antivirals requires years of research and validation, and recent outbreaks have highlighted the need for preparedness in counteracting pandemics. One way to facilitate development is to repurpose molecules already used clinically. By screening such compounds, we can accelerate antiviral development. Here, we screened compounds from the National Institutes of Health’s Developmental Therapeutic Program for activity against chikungunya virus, an alphavirus that is responsible for a significant outbreak in the Americas in 2013. Using this …

Elucidating The Function Of An Evolutionarily Conserved Col2Α1 Isoform During Vertebrate Development, Charles Lantz H. Ingersoll

Master's Theses

ABSTRACT

Formation of skeletal structural elements during vertebrate embryogenesis is largely a

conserved evolutionary process that employs numerous conserved genes and pathways. One

critical gene in this process is the highly conserved vertebrate Type II Collagen alpha 1 (col2α1).

It produces multiple splice isoforms that have different functions and expression patterns during

skeletogenesis. Two of the primary isoforms are of great interest; variant 1, the primary

embryonic isoform, and variant 2, a post embryonic isoform. While the more commonly known

post-embryonic isoform has been well studied over the last 30 years, identification of a unique

role for the evolutionarily conserved …