Metabolomics Reveal Size-Dependent Impacts Of Cerium Oxide Nanoparticles On Grains Of Barley (Hordeum Vulgare L.), Naum Jepkemei Kirwa

Graduate Theses/Dissertations

Plants are exposed to emerging contaminants including nanoparticles, due to the novel but wide uses of these materials. However, researchers have shown contradicting effects of CeO₂-NPs on barley grains with focus mostly on concentration effects and not sizes of these CeO₂-NPs. Therefore, this study aimed at comparing the effects of 0nm (control), 8nm, and 40nm (250 mg CeO₂-NPs/kg soil) on the metabolite profile of barley grains. GC-FID and GC-QTOF-MS were used to measure fatty acid contents and metabolomic changes respectively. GC-FID analysis revealed that palmitic acid, oleic acid, linoleic acid, and the total fatty …

Public Perceptions Of Human Physical Interactions, Exhibition, And Conservation Of Tigers And Cheetahs, Abbie Knudsen

Graduate Theses/Dissertations

Tigers and cheetahs are common in the pet trade, public exhibits, and hands-on encounters with the public. Poor regulation of these experiences has resulted in numerous incidents worldwide in which a person was seriously injured or killed by captive big cats. Additionally, concerns for animal welfare have been raised by industry professionals. Prior research on primates has demonstrated exposing people to photographs of cats in different backgrounds can influence their attitudes about animals in captivity, but no study has addressed whether visual images affect human attitudes toward big cats. I used a survey that asked a series of questions about …

Streaming Property, Lee Anne Fennell

Public Law and Legal Theory Working Papers

People acquire property rights in objects and real estate in order to capture the stream of services that these assets can provide over time. The thing or parcel itself is merely a delivery mechanism, a way of packaging and protecting rights to that value stream. And, significantly, these assets cannot stream services to anyone without a set of facilitating conditions and complementary goods, such as public infrastructure, that do not lie within the asset owner’s individual control. This Essay argues that we can gain fresh traction on inequality by recasting property as service streams rather than as owned things. Doing …

Bipolar Screening Among Spanish-Speaking Us Residents Using The Mood Disorder Questionnaire, Emanuel T. Recinos

Doctor of Psychology (PsyD)

The Mood Disorder Questionnaire (MDQ) is a self-report screening instrument used to detect Bipolar Disorder (BD). Psychometric properties of Spanish translations of the MDQ are from communities where both language and cultural differences are present. A Spanish version of the MDQ not been validated among United States individuals who identify Spanish as their preferred language of communication.

Objective

We propose that the validation of a Castilian Spanish version of the MDQ is needed for cross-cultural adaptation, determining optimal cut-off scores, and as an aid to the literature on BD prevalence, specifically BD among Spanish speakers of the United States.

Methods …

Dordt University 2022-23 Catalog, Dordt University. Registrar's Office

Academic Catalogs

Academic catalog for 2022-23

Transformed Waldenström Macroglobulinemia Responsive To Tafasitamab Plus Lenalidomide: A Case Report, Syed Alishan Nasir, Deep Pandya, Steven Wojkiewicz, Bhavna Khandpur, Elizabeth Downes, Pradip Pathare, Richard Frank

Physician Associate Studies Faculty Publications

The histologic transformation (HT) of Waldenström macroglobulinemia (WM) into diffuse large-cell lymphoma is an uncommon but poor-prognostic event for which there is no standard therapy. Knowledge of this entity is mainly derived from largely retrospective studies, which report abysmal average survival rates even with the utilization of first-line chemoimmunotherapy and especially in patients who meet the high-risk criteria based on prognostic indices used for WM. We present the case of a 75-year-old man with high-risk, transformed WM who was ineligible for standard chemoimmunotherapy (due to pancytopenia and multiple comorbidities) and was consequently treated with tafasitabmab, an anti-CD19 monoclonal antibody plus …

Science Methods For Elementary Teachers, Ron Browne, David Kimori

MSU Authors Collection

Complete Digitized Text of Science Methods for Elementary Teachers by Ron Browne and David Kimori, Minnesota State University, Mankato, 2022.

An Investigation Of The Perception Of Elderspeak Among Community Dwelling Older Adults, Abby L. Teply

All Graduate Theses, Dissertations, and Other Capstone Projects

This study aimed to expand the literature on the perception of elderspeak among community dwelling older adults with secondary purposes concerning how these perceptions vary across gender and region. Participants (n = 110) were presented a written vignette that depicted a nursing assistant in an assisted living facility waking a tenant from a nap and assisting the tenant to the bathroom before lunch. The nursing assistant uses elderspeak throughout the vignette. Following the vignette, participants’ reactions to the use of elderspeak and perceptions of the nursing assistant in the vignette were assessed using a series of open-ended questions, the Positive …

Functional Trade-Offs Between Terrestrial And Aquatic Locomotion In The Amphibious Fish Kryptolebias Marmoratus, Erik Axlid

All Graduate Theses, Dissertations, and Other Capstone Projects

The mangrove rivulus (Kryptolebias marmoratus) is a phenotypically plastic teleost fish that can spend considerable time on land and traverse the terrestrial realm through a ballistic behavior termed the tail-flip jump. The tail-flip jump is a transitional stage between fully aquatic and terrestrial lifestyles. Therefore, understanding this behavior can provide insight into how organisms adapt to new environments over evolutionary time. Taxa that are successful tail-flip jumpers have a deep caudal peduncle and uniform body shape. Studies of K. marmoratus show that terrestrial acclimation and exercise improves tail-flip jumping performance due to muscle remodeling, but the implications of these muscular …

Important Aspects To Women’S Re-Integration: Positive Influences On Women’S Reentry Experience After Being Released From Prison, Sarah A. Benson

All Graduate Theses, Dissertations, and Other Capstone Projects

Researchers can analyze statistics of recidivism rates and decipher that they are at an alarming rate—specifically regarding women convicts. The population of women in prison has drastically increased, and with that, so have their recidivism rates. Analyzing statistical data of incarceration and recidivism can show us the numbers, but what is the reason? Why do some women struggle to stay out of prison? I argued that one reason is because women who are released from prison are severely underprepared to reintegrate back into society and, are therefore, set up for failure. Previous studies suggest that reentry programs, education programs, relationships …

Perceptions Of Well-Being Among College Majors, Baylee Jahraus

All Graduate Theses, Dissertations, and Other Capstone Projects

The purpose of this research was to assess the well-being perceptions of selected college students at a midsize midwestern university. To collect data, an adaptation of the Open Science Framework’s (n.d) College Student Subjective Wellbeing Questionnaire and the CDC’s (2018b) Health-related Quality of Life scale was used. The 26-item survey was distributed to junior and senior students enrolled in 300-400 level courses in a variety of majors. The findings for each research question are presented in the cross-sectional study. The results of the study indicate there are differences in perceptions of physical and mental health between males and females and …

Pre-Exposure Of Escherichia Coli And Staphylococcus Aureus To Sub-Bactericidal Concentrations Of Benzalkonium Chloride And Its Effect On Low-Level Antimicrobial Resistance, Logan Fette

All Graduate Theses, Dissertations, and Other Capstone Projects

Antimicrobial resistance that develops in bacteria is a highly studied aspect of microbiology due to the concerns that it poses for public health. Antibiotics remain our primary care option when dealing with bacterial infections. The concept of tolerance of bacteria to disinfectants is similar and it also poses a significant health risk. Since use of disinfectants for sanitation is a primary manner in which we are able to prevent potential infections from occurring in the first place, it can be a helpful means to preventing development of antimicrobial resistance. However, what has not been explored to the same extent is …

Function And Expression Of Ribonucleotide Reductase-Encoding Genes In Flavobacterium Johnsoniae, Hunter Scott Doheny

All Graduate Theses, Dissertations, and Other Capstone Projects

Ribonucleotide reductases (RNRs) are essential enzymes that are involved in DNA synthesis. While this makes them ideal targets for antiproliferative drugs, most known RNR targeting agents are nonspecific. This poses a problem when considering antimicrobials, but several groups of bacteria have RNRs that utilize unique mechanisms that could be exploited if fully understood. One such bacteria, Flavobacterium johnsoniae, has the gene for a class Id RNR with a novel activation mechanism. Class Id RNRs belong to the aerobic class I RNRs and seem to have a unique metallocofactor and activation mechanism involving superoxide and manganese. The goal of this research …

Development Of Genetic Manipulation Techniques For The Fish Pathogen Flavobacterium Psychrophilum, Seada Sloboda

All Graduate Theses, Dissertations, and Other Capstone Projects

Flavobacterium psychrophilum is a known fish pathogen, causing bacterial cold-water disease (BCWD) and rainbow trout fry syndrome (RTFS), predominantly in salmonids. The disease causes tissue damage and tail rot in young and adult fish. The issue is prevalent in fisheries in the Pacific Northwest and the treatments often entail the use of antibiotics. Genetic manipulations in F. psychrophilum are scarce, due to most of the strains’ ability to destroy foreign DNA via restriction enzymes. The virulence mechanisms of F. psychrophilum are not well understood. Lack of genetic manipulation tools in F. psychrophilum has also hampered the development of live attenuated …

Environmental Effects On Biomass Allocation And Small Plot Evaluations Of Aquatic Pesticides For Control Of Nitellopsis Obtusa (Starry Stonewort) Collected From Lake Koronis In Stearns County, Minnesota, Patrick J. Carver

All Graduate Theses, Dissertations, and Other Capstone Projects

Phenology is the study of critical life stages in plants in relation to shifts in environmental factors during seasonal changes. Starry stonewort is a green macro alga in the family Characeae native to Eurasia. Much of the Midwestern United States has been invaded by this species. Starry stonewort has been seen to have late season growth patterns in its invaded range. This study found that this growth pattern was dependent upon water temperature and light transmittance both of which affect biomass production and senescence. It was hypothesized that peak biomass would occur in the late summer (August), however we observed …

A Socio-Historical Analysis Of The Dynamics Of Genocide In Bosnia 1992-1995: Forces Contributing To The Continuation Of Genocide, Lejla Alvarez

All Graduate Theses, Dissertations, and Other Capstone Projects

Despite preventive and diagnostic instruments and mechanisms put in place by the international community, genocide - systematic destruction of social groups - persists as a major regional and global problem. Genocidal processes are multifaceted and involve multiple factors at all levels of analysis interacting to produce genocide. This study examines the most significant socio-historical factors in producing the genocidal war in Bosnia that started in the spring of 1992, carried out generally uninterrupted until late 1995, with some forms of violence continuing years after the official end of the war. The main goals of the research were to contextualize the …

Understanding The Unstably Housed: Assessing The Systemic Gaps Of Young Adults Who Are “Doubling Up” In Washington State, Chelsea Perry

Master of Arts in Criminal Justice Theses

Youth and young adults exiting the juvenile justice system are at risk for entering a new system- the homeless system. This current research aims to understand the conditions that youth enter the homeless system. Current research and homeless reports from point in time (PIT) counts and other databases do not measure specific circumstances of housing instability such as couch surfing or “doubling up” with friends and close relatives versus couch surfing with strangers, and whether there are potentially criminogenic transactions or conditions that juveniles must adhere to in order to sustain this temporary housing. Methods include two areas of analysis. …

Patient Transitions Between Acute And Post-Acute Care Organizations: Can Nursing Communication Prevent Patient Readmission?, Penny Gilbert

DNP Projects

Preventing Patient Readmission

Background and Review of Literature: Communication is the foundation of patient safety. As patients move from the acute to post-acute care setting, risk for insufficient communication rises. Research demonstrates a vast array of communication hand-off tools currently exist for and between different care arenas. No one tool has been standardized for patients transitioning from acute to post-acute care settings. The Institute of Medicine (IOM) and The Joint Commission (TJC) have published multiple documents discussing communication plagues within health care resulting in readmission.

Purpose: The purpose of this project is multifaceted: 1) identifying current nursing communication practices between …

An Ecological Study Of Glyphosate Use And Non-Hodgkin’S Lymphoma, Dexter Corlett, Steven R. Browning

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Glyphosate is currently the most widely used herbicide in the world. Initially thought to be non-carcinogenic in humans, in 2015 glyphosate was classified as a “probable carcinogen” by the International Agency for Research on Cancer due to several small epidemiological studies indicating a link between the pesticide and hematologic cancers, especially non-Hodgkin’s lymphoma (NHL). The current work is an ecological study using counties in Kentucky, Arkansas, and Iowa to compare glyphosate usage to NHL incidence using a multivariate Poisson regression. We found no significant correlation between glyphosate use and NHL incidence, though caution should be taken to draw significance from …

Siege Starvation: A War Crime Of Societal Torture, Tom Dannenbaum

Chicago Journal of International Law

A recent amendment to the Rome Statute of the International Criminal Court has drawn unprecedented attention to the war crime of starvation of civilians as a method of warfare. It comes at a time when mass starvation in war is resurgent, devastating populations in Yemen, Ethiopia, Syria, South Sudan, Nigeria, and elsewhere. The practice has also drawn the scrutiny of the United Nations Security Council. And yet, despite this heightened profile and sharpened urgency, what precisely is criminally wrongful about starvation methods remains underspecified.

A common way of thinking about the criminal wrong is as a form of killing or …

Searching For Justice For Australia’S Stolen Generations, Keila Mayberry

Chicago Journal of International Law

Until the early 1970s, Australian federal and state government agencies forcibly removed tens of thousands of Aboriginal and Torres Strait Islander children from their families and placed them up for adoption or in group homes and church missions. These children are known as the “Stolen Generations.” Domestic remedies have proven insufficient in securing justice for the Stolen Generations and international adjudication may be a viable alternative. This Comment examines whether Australia may be haled before the International Court of Justice (ICJ) for violations of the Genocide Convention for its Stolen Generations policies. Australia’s policies likely constituted a violation of Article …

Changing Selection And Epistasis On Drivers Over Tumorigenesis In Primary And Metastatic Prostate Cancer, Alexander Yang

Yale Medicine Thesis Digital Library

Background: Many attempts have been made to characterize and describe the driver genes and mutations responsible for prostate cancer tumorigenesis. We have quantified the cancer effect size—a direct measurement of the survival advantage a mutation confers—for 2699 primary and metastatic prostate tumor samples. Our measure of cancer effect treats tumorigenesis as an evolutionary process, subject to positive and negative selective pressures. We have applied this metric in a stage-specific manner to elucidate which mutations are selected for as prostate cancer develops.Methods: We analyzed 2699 prostate cancer tumor exomes, genomes, and panel sequences (1648 primary tumors and 1051 metastatic samples). The …

Presurgical Tear Characteristics And Estimated Shear Modulus As Predictors Of Repair Integrity And Shoulder Function One Year After Rotator Cuff Repair, Matthew C. Ruder, Rebekah L. Lawrence, Steven B. Soliman, Michael J. Bey

Orthopedics Articles

Background: Rotator cuff repair provides pain relief for many patients; however, retears are relatively common and affect approximately 20%-70% of patients after repair. Although magnetic resonance imaging (MRI) offers the ability to assess tissue characteristics such as tear size, retraction, and fatty infiltration, it provides little insight into the quality of the musculotendinous tissues the surgeon will encounter during surgery. However, shear wave elastography (SWE) could provide an indirect assessment of quality (ie, stiffness) by measuring the speed of shear waves propagating through tissue. The objective of this study was to determine the extent to which estimated shear modulus predicts …

Feeding Different Iodine Sources To Dairy Cows: Effects On Colostrum Production And Growth And Health Of Their Calves, Kayla Renee Johnston

Master's Theses and Capstones

Limited research exists on supplementing seaweeds to prepartum cows and its effects on colostrum production and development of their calves in-utero and after birth. The high iodine (I) concentration of seaweeds is concerning, and previous research have shown that excess I supplementation to ewes inhibits immunoglobulin G (IgG) absorption in their lambs. The objectives of this study were: (1) evaluate the effects of incremental amounts of Ascophyllum nodosum (ASCO) meal supplementation (0, 57, and 113 g/d) to prepartum cows on colostrum production and subsequent growth, health, and blood concentrations of glucose, β-hydroxybutyric acid (BHBA), and thyroid hormones (TH) of their …

Seasonal Assessments Of Bioregeneration In Slow Sand Filters Amended With Granular Activated Carbon, Katherine R. Morsefield

Master's Theses and Capstones

The application of slow sand filtration (SSF) has conventionally proven to be a reliable and relatively inexpensive means of producing potable drinking water for decades. As technologies in drinking water treatment continue to advance, innovations to the design and operation of slow sand filtration have the ability to transform its contribution in municipal and industrial settings. SSF amended with granular activated carbon (GAC) has been on the rise in recent decades due to its ability to improve the removal of organic material, while allowing SSF to maintain its innate treatment simplicity.

A slow sand filter amended with granular activated carbon …

Supplementing Sodium Butyrate To Limit-Fed Heifers: Effects On Growth, Health, And Nutrient Digestibility & Effect Of Sodium Butyrate On Viability Of Eimeria Bovis Sporozoites And Ldh Release From Mdbk Cells In The Presence Of Sporozoites, Katrina Klobucher

Master's Theses and Capstones

Two experiments were conducted to investigate the effects of sodium butyrate (SB) supplementation in heifer diets. The objectives of experiment 1 was to evaluate the growth, apparent total tract digestibility, and coccidia levels of post-weaned limit-fed heifers supplemented with SB. A 12 week randomized complete block experiment was conducted using 24 Holstein heifers. Treatments were 100g soybean meal (control; CON) and 0.75 g of SB/kg of body weight + 100g soybean meal (SB). Diets were formulated to contain 16.4 % crude protein (CP), 2.27 Mcal/kg metabolizable energy (ME), and fed at a rate of 2.15% of body weight on a …

Enhanced Late Miocene Organic Carbon Preservation And Sulfur Sequestration Beneath The Oxygen Deficient Zone In The Eastern Arabian Sea, Sophie Lee Alpert

Master's Theses and Capstones

The ocean represents the largest sulfur pool on Earth, with 1.3 x 109 Tg of sulfur present in seawater. Marine sediment sulfur sequestration is the primary sink for seawater sulfate, responsible for the burial and storage of 100 Tg of sulfur per year. The sequestration of sulfur in marine sediments is largely driven by the formation of iron monosulfides, metastable iron sulfide minerals, and pyrite, however the different paths driving the degree of pyritization within marine sediments require different environmental conditions and carbon sources. In this thesis research, the possible diagenetic pathways resulting in sulfur sequestration are investigated in a …

The Biochemistry Of Ursolic Acid: A Potential Therapeutic For Neuro-Inflammation, Emma Jane Arsenault

Master's Theses and Capstones

Ursolic acid (UA) is a naturally occurring triterpenoid found in a variety of plants and berries. This molecule has potent antioxidant and anti-inflammatory properties with the potential to treat a wide variety of conditions, including neuro-inflammatory disorders. However, the exact mechanism of action for UA is unknown. In this thesis, the fundamental biochemistry of UA was investigated by studying two potential targets: lipid rafts and protein phosphatases. Lipid rafts are an important platform for a wide variety of signal transduction pathways and are a docking point for the assembly of the pro-inflammatory NADPH oxidase 2. The impact of UA on …

Investigation Of Multiple Cyanotoxins In Toxic Lake Aerosols, Hailey Carter

Master's Theses and Capstones

Aerosols from freshwater lakes with toxigenic cyanobacteria pose a potentially serious threat to humans and wildlife. The most studied route of exposure to cyanotoxins is direct consumption (i.e., drinking contaminated water or eating contaminated food). However, a less studied but a potentially important route of exposure is inhalation of aerosolized cyanotoxins. Three toxins, produced by cyanobacteria, examined in this study were hepatoxicmicrocystins (MC),and the neurotoxins?-Methylamino-?-alanine (BMAA), and anatoxin-a (ATX). Using a compact lake aerosol monitor(CLAM), this study measured levels of aerosolized cyanotoxins(MC, BMAA, and ATX) at two shallow and inter-connected lakes, Walkers Pond and Lower Mill Pond (Brewster, MA, USA),biweekly …

Water-Soluble Reversible Addition-Fragmentation Chain Transfer (Raft) Agents And Their Bioconjugation To Dsdna, Dylan F. Finneran

Master's Theses and Capstones

Understanding the properties of bioconjugates and biomaterials has increasingly become the focus of pharmaceutical companies, material scientists, and academia due to their growing list of applications. Bioconjugates have found broad use in therapeutics, drug delivery, tissue engineering, and biosensing. Historically, interest in specific bioconjugates has depended on the cost-availability of the biomacromolecule, making proteins the most well studied, given their relatively low cost and ease of production. However, recent technological advances in plasmid DNA (pDNA) production from E. Coli allow for greater cost-efficiency, changing the landscape of biomaterial research. Employing alkylating agents with known chemo-selectivity to nucleophilic sites on DNA, …