Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Life Sciences (8198)
- Medicine and Health Sciences (7489)
- Physical Sciences and Mathematics (4044)
- Social and Behavioral Sciences (3983)
- Medical Specialties (2571)
-
- Education (2473)
- Medical Sciences (2319)
- Arts and Humanities (1987)
- Engineering (1928)
- Biology (1814)
- Law (1422)
- Psychology (1187)
- Plant Sciences (1159)
- Ecology and Evolutionary Biology (1055)
- Environmental Sciences (1017)
- Public Health (950)
- Chemistry (926)
- Oncology (885)
- Bioinformatics (884)
- Animal Sciences (838)
- Higher Education (809)
- Earth Sciences (806)
- Biomedical Informatics (730)
- Biochemistry, Biophysics, and Structural Biology (723)
- Agriculture (649)
- Diseases (633)
- Plant Biology (622)
- Sociology (618)
- Agronomy and Crop Sciences (616)
- Agricultural Science (581)
- Institution
-
- The Texas Medical Center Library (1769)
- University of Nebraska - Lincoln (1235)
- Washington University School of Medicine (775)
- University of Kentucky (667)
- TÜBİTAK (586)
-
- Louisiana State University (531)
- University of Plymouth (469)
- Chulalongkorn University (460)
- Utah State University (439)
- University of Arkansas, Fayetteville (437)
- City University of New York (CUNY) (412)
- Brigham Young University (395)
- University of South Florida (387)
- University of South Carolina (378)
- University of Mississippi (376)
- Thomas Jefferson University (361)
- University of Texas Rio Grande Valley (361)
- University of Montana (341)
- Walden University (340)
- Nova Southeastern University (326)
- Liberty University (297)
- University of Memphis (288)
- University of Central Florida (283)
- Portland State University (279)
- Yale University (274)
- University of New Hampshire (247)
- University of Rhode Island (242)
- Clemson University (239)
- Edith Cowan University (233)
- University of New Mexico (217)
- Keyword
-
- Humans (1624)
- Animals (710)
- COVID-19 (520)
- Mice (516)
- Female (404)
-
- Male (253)
- Climate change (209)
- SARS-CoV-2 (188)
- Education (179)
- Biology (171)
- Machine learning (171)
- Gender (170)
- Child (160)
- Cancer (158)
- Adult (147)
- ICTS (Institute of Clinical and Translational Sciences) (142)
- Inflammation (141)
- Depression (137)
- Biomarkers (131)
- Mental health (131)
- Neoplasms (131)
- Obesity (123)
- Genomics (121)
- Immunotherapy (115)
- Stress (113)
- Ecology (112)
- Pregnancy (112)
- Retrospective Studies (111)
- Mutation (109)
- Conservation (108)
- Publication
-
- Faculty, Staff and Student Publications (1114)
- Theses and Dissertations (972)
- 2020-Current year OA Pubs (569)
- Faculty Publications (553)
- Electronic Theses and Dissertations (446)
-
- Faculty, Staff and Students Publications (413)
- Chulalongkorn University Theses and Dissertations (Chula ETD) (390)
- IGC Proceedings (1977-2023) (359)
- Dissertations (324)
- Walden Dissertations and Doctoral Studies (313)
- Honors Theses (256)
- Yale Graduate School of Arts and Sciences Dissertations (202)
- Research outputs 2022 to 2026 (201)
- Open Access Publications (198)
- USF Tampa Graduate Theses and Dissertations (192)
- School of Biological and Marine Sciences (182)
- Doctoral Dissertations and Projects (176)
- Baltic Journal of Health and Physical Activity (172)
- Food and Machinery (168)
- Theses (167)
- University of Montana Course Syllabi, 2021-2025 (167)
- Graduate Theses and Dissertations (164)
- Master's Theses (154)
- Articles (149)
- Dissertations, Theses, and Capstone Projects (145)
- Graduate Theses, Dissertations, and Problem Reports (ETD) (142)
- Faculty Scholarship (135)
- Dissertations and Theses (131)
- Journal of Marine Science and Technology–Taiwan (125)
- Florida Law Review (124)
- Publication Type
Articles 20731 - 20760 of 32113
Full-Text Articles in Entire DC Network
Untangling The Placentome Gene Network Of Beef Heifers In Early Gestation, Wellison J.S. Diniz, Lawrence P. Reynolds, Alison K. Ward, Pawel P. Borowicz, Kevin K. Sedivec, Kacie L. Mccarthy, Cierrah J. Kassetas, Friederike Baumgaertner, James D. Kirsch, Sheri T. Dorsam, Tammi L. Neville, J. Chris Forcherio, Ronald R. Scott, Joel S. Caton, Carl R. Dahlen
Untangling The Placentome Gene Network Of Beef Heifers In Early Gestation, Wellison J.S. Diniz, Lawrence P. Reynolds, Alison K. Ward, Pawel P. Borowicz, Kevin K. Sedivec, Kacie L. Mccarthy, Cierrah J. Kassetas, Friederike Baumgaertner, James D. Kirsch, Sheri T. Dorsam, Tammi L. Neville, J. Chris Forcherio, Ronald R. Scott, Joel S. Caton, Carl R. Dahlen
Department of Animal Science: Faculty Publications
The cotyledon and caruncle tissues provide a functional bridge between the fetus and the dam. However, the relationship between these tissues and the transcriptomic profile that underlies the tissue functions remains elusive. Herein we investigate the expression profile of cotyledon and caruncle from nulliparous beef heifers carrying female fetuses at day 83 of pregnancy to identify changes occurring across tissues that contribute to placental function and their tissue-specific roles. We identified 2654 differentially expressed genes [padj ≤ 0.05, abs(log2FC) ≥ 1], including nutrient transporters and paternally imprinted genes. We found key regulators of tissue function and differentiation, including FOXO4, GATA2, …
The Coastal Monitor: Vol. 8 No. 4, John Tanacredi Ph.D.
The Coastal Monitor: Vol. 8 No. 4, John Tanacredi Ph.D.
The Coastal Monitor
The original five acre of land portion of the historic Blue Points Oyster Company is located at the southern end of Atlantic Ave in West Sayville, Islip Town, Suffolk County, New York on the shore of Great South Bay. The Center for Environmental Research and Coastal Oceans Monitoring (CERCOM) is the science field station serving Molloy College’s BCES programs in Earth & Environmental Sciences and Biology. Our mission is to provide unique hands-on educational opportunities in the physical and life sciences, in collaboration with a host of Federal, State, and local and NGO groups, to bolster students’ career path. Great …
Cannabinoids For The Treatment Of Dermatologic Conditions, Torunn E. Sivesind, Jalal Maghfour, Hope Rietcheck, Kevin Kamel, Ali S. Malik, Robert P. Dellavalle
Cannabinoids For The Treatment Of Dermatologic Conditions, Torunn E. Sivesind, Jalal Maghfour, Hope Rietcheck, Kevin Kamel, Ali S. Malik, Robert P. Dellavalle
Dermatology Articles
In recent years, cannabinoid (CB) products have gained popularity among the public. The anti-inflammatory properties of CBs have piqued the interest of researchers and clinicians because they represent promising avenues for the treatment of autoimmune and inflammatory skin disorders that may be refractory to conventional therapy. The objective of this study was to review the existing literature regarding CBs for dermatologic conditions. A primary literature search was conducted in October 2020, using the PubMed and Embase databases, for all articles published from 1965 to October 2020. Review articles, studies using animal models, and nondermatologic and pharmacologic studies were excluded. From …
Current Water Quality Guidelines Across North America And Europe Do Not Protect Lakes From Salinization, Matthew Schuler
Current Water Quality Guidelines Across North America And Europe Do Not Protect Lakes From Salinization, Matthew Schuler
Department of Biology Faculty Scholarship and Creative Works
Human-induced salinization caused by the use of road deicing salts, agricultural practices, mining operations, and climate change is a major threat to the biodiversity and functioning of freshwater ecosystems. Yet, it is unclear if freshwater ecosystems are protected from salinization by current water quality guidelines. Leveraging an experimental network of land-based and in-lake mesocosms across North America and Europe, we tested how salinization—indicated as elevated chloride (Cl2) concentration—will affect lake food webs and if two of the lowest Cl2 thresholds found globally are sufficient to protect these food webs. Our results indicated that salinization will cause substantial …
The Corkscrew Technique For Removing A Fibular Strut Allograft From The Proximal Humerus., Brian Skura, Matthew T Glazier, Hayden B Schuette, Braden J Passias, Iou-Ren Chang, John Verre, Sanjay Mehta, Benjamin C Taylor
The Corkscrew Technique For Removing A Fibular Strut Allograft From The Proximal Humerus., Brian Skura, Matthew T Glazier, Hayden B Schuette, Braden J Passias, Iou-Ren Chang, John Verre, Sanjay Mehta, Benjamin C Taylor
Surgery Articles
A fibular strut allograft is a reliable option for augmentation in open reduction internal fixation (ORIF) of proximal humerus fractures, but techniques to remove a fibular strut during revision shoulder arthroplasty are limited. Currently published techniques on extracting fibular strut grafts from humeral shafts include using a Midas burr, flexible osteotomes, humeral shaft osteotomy, and reaming. To our knowledge there has not been a technique that uses a corkscrew to remove the fibular strut from the proximal humerus in preparation for revision shoulder arthroplasty. This is a case report and description of a simple and reproducible technique that can be …
Epidemiological Algorithm For Early Detection Of Covid-19 Cases In A Mexican Oncologic Center, Moisés González-Escamilla, Diana Cristina Pérez-Ibave, Carlos Horacio Burciaga-Flores, Vanessa Natali Ortiz-Murillo, Genaro A. Ramírez-Correa, Patricia Rodríguez-Niño, Rafael Piñeiro-Retif, Hazyadee Frecia Rodríguez-Gutiérrez, Fernando Alcorta-Nuñez
Epidemiological Algorithm For Early Detection Of Covid-19 Cases In A Mexican Oncologic Center, Moisés González-Escamilla, Diana Cristina Pérez-Ibave, Carlos Horacio Burciaga-Flores, Vanessa Natali Ortiz-Murillo, Genaro A. Ramírez-Correa, Patricia Rodríguez-Niño, Rafael Piñeiro-Retif, Hazyadee Frecia Rodríguez-Gutiérrez, Fernando Alcorta-Nuñez
School of Medicine Publications
An early detection tool for latent COVID-19 infections in oncology staff and patients is essential to prevent outbreaks in a cancer center. (1) Background: In this study, we developed and implemented two early detection tools for the radiotherapy area to identify COVID-19 cases opportunely. (2) Methods: Staff and patients answered a questionnaire (electronic and paper surveys, respectively) with clinical and epidemiological information. The data were collected through two online survey tools: Real-Time Tracking (R-Track) and Summary of Factors (S-Facts). Cut-off values were established according to the algorithm models. SARS-CoV-2 qRT-PCR tests confirmed the positive algorithms individuals. (3) Results: Oncology staff …
The Clock Modulator Nobiletin Mitigates Astrogliosis-Associated Neuroinflammation And Disease Hallmarks In An Alzheimer’S Disease Model, Marvin Wirianto, Chih-Yen Wang, Eunju Kim, Nobuya Koike, Ruben Gomez-Gutierrez, Kazunari Nohara, Gabriel Escobedo, Jong Min Choi, Chorong Han, Kazuhiro Yagita, Sung Yun Jung, Claudio Soto, Hyun Kyoung Lee, Rodrigo Morales, Seung-Hee Yoo, Zheng Chen
The Clock Modulator Nobiletin Mitigates Astrogliosis-Associated Neuroinflammation And Disease Hallmarks In An Alzheimer’S Disease Model, Marvin Wirianto, Chih-Yen Wang, Eunju Kim, Nobuya Koike, Ruben Gomez-Gutierrez, Kazunari Nohara, Gabriel Escobedo, Jong Min Choi, Chorong Han, Kazuhiro Yagita, Sung Yun Jung, Claudio Soto, Hyun Kyoung Lee, Rodrigo Morales, Seung-Hee Yoo, Zheng Chen
Faculty, Staff and Student Publications
Alzheimer's disease (AD) is a devastating neurodegenerative disorder, and there is a pressing need to identify disease-modifying factors and devise interventional strategies. The circadian clock, our intrinsic biological timer, orchestrates various cellular and physiological processes including gene expression, sleep, and neuroinflammation; conversely, circadian dysfunctions are closely associated with and/or contribute to AD hallmarks. We previously reported that the natural compound Nobiletin (NOB) is a clock-enhancing modulator that promotes physiological health and healthy aging. In the current study, we treated the double transgenic AD model mice, APP/PS1, with NOB-containing diets. NOB significantly alleviated β-amyloid burden in both the hippocampus and the …
Counterfactual Analysis Of Differential Comorbidity Risk Factors In Alzheimer’S Disease And Related Dementias, Yejin Kim, Kai Zhang, Sean I Savitz, Luyao Chen, Paul E Schulz, Xiaoqian Jiang
Counterfactual Analysis Of Differential Comorbidity Risk Factors In Alzheimer’S Disease And Related Dementias, Yejin Kim, Kai Zhang, Sean I Savitz, Luyao Chen, Paul E Schulz, Xiaoqian Jiang
Faculty, Staff and Student Publications
Alzheimer’s disease and related dementias (ADRD) is a multifactorial disease that involves several different etiologic mechanisms with various comorbidities. There is also significant heterogeneity in the prevalence of ADRD across diverse demographics groups. Association studies on such heterogeneous comorbidity risk factors are limited in their ability to determine causation. We aim to compare counterfactual treatment effects of various comorbidity in ADRD in different racial groups (African Americans and Caucasians). We used 138,026 ADRD and 1:1 matched older adults without ADRD from nationwide electronic health records, which extensively cover a large population’s long medical history in breadth. We matched African Americans …
Racialized Disablement And The Need For Conceptual Analysis Of “Racial Health Disparities”, Desiree Valentine
Racialized Disablement And The Need For Conceptual Analysis Of “Racial Health Disparities”, Desiree Valentine
Philosophy Faculty Research and Publications
It is well established that racial health disparities are impacted by structural racism, but the imbrication of racialization processes with processes of disablement remains underdeveloped. This essay advocates for a conceptual lens that looks historically and politically at the co-constitution of “race” and “disability.” Racism and ableism intersect in ways that manifest what I call racialized disablement, a key heuristic for building a fuller understanding of “race” and “racial health disparities.” This terminology, I propose, helps illuminate the following about race and racism in healthcare: first, racialized disablement seeks to denaturalize both race and disability to focus on their political …
Instructional Models For Course-Based Research Experience (Cre) Teaching, David I. Hanauer, Mark J. Graham, Rachel J. Arnold, Mary A. Ayuk, Mitchell F. Balish, Andrea R. Beyer, Kristen A. Butela, Christine A. Byrum, Catherine P. Chia, Hui Min Chung, Kari L. Clase, Stephanie Conant, Roy J. Coomans, Tom D'Elia, Jason Diaz, Arturo Diaz, Jean A. Doty, Nicholas P. Edgington, Dustin C. Edwards, Elvira Eivazova, Christine B. Emmons, Kayla M. Fast, Viknesh Sivanathan, And About 50 Others
Instructional Models For Course-Based Research Experience (Cre) Teaching, David I. Hanauer, Mark J. Graham, Rachel J. Arnold, Mary A. Ayuk, Mitchell F. Balish, Andrea R. Beyer, Kristen A. Butela, Christine A. Byrum, Catherine P. Chia, Hui Min Chung, Kari L. Clase, Stephanie Conant, Roy J. Coomans, Tom D'Elia, Jason Diaz, Arturo Diaz, Jean A. Doty, Nicholas P. Edgington, Dustin C. Edwards, Elvira Eivazova, Christine B. Emmons, Kayla M. Fast, Viknesh Sivanathan, And About 50 Others
School of Biological Sciences: Faculty Publications
The course-based research experience (CRE) with its documented educational benefits is increasingly being implemented in science, technology, engineering, and mathematics education. This article reports on a study that was done over a period of 3 years to explicate the instructional processes involved in teaching an undergraduate CRE. One hundred and two instructors from the established and large multi-institutional SEA-PHAGES program were surveyed for their understanding of the aims and practices of CRE teaching. This was followed by large-scale feedback sessions with the cohort of instructors at the annual SEA Faculty Meeting and subsequently with a small focus group of expert …
Substance Abuse's Impact On Public Accounting, William Dennis Holmes
Substance Abuse's Impact On Public Accounting, William Dennis Holmes
Doctoral Dissertations and Projects
A case study was performed to determine best practices for handling substance use disorder (SUD) when the problem occurs in business. SUD is a common problem that affects most businesses. The problem can result in high costs to businesses and is often difficult to navigate. The problem identified in the study was investigated by answering the primary research questions established in the planning stages of the study. An exhaustive literature review was performed on the topic, and common themes were discovered during a review of the literature. After the planning stage, the researcher performed a case study. Interviews of 23 …
The Experiences Of African American Graduate Students Attending Colleges Of Chiropractic: A Hermeneutical Phenomenology, Darren De'un Howland
The Experiences Of African American Graduate Students Attending Colleges Of Chiropractic: A Hermeneutical Phenomenology, Darren De'un Howland
Doctoral Dissertations and Projects
The purpose of this hermeneutical phenomenological study is to discover and interpret the campus experiences of African American graduate students attending colleges of chiropractic in the United States. A sense of belonging within a campus environment is essential to all students that encounter a university. The campus environment has an important role in the retention of African American students. The theory guiding this study is the Culturally Engaging Campus Environment Model which examines cultural engagement within the campus environment. The central question leading this research study asks, “What are the lived experiences of African American graduate students attending colleges of …
A Study Of K-12 Classroom Teachers' Concerns And Perceived Self-Efficacy In Implementing Inclusive Teaching Practices To Instruct Students With Disabilities, Pankaj Khazanchi
A Study Of K-12 Classroom Teachers' Concerns And Perceived Self-Efficacy In Implementing Inclusive Teaching Practices To Instruct Students With Disabilities, Pankaj Khazanchi
Doctoral Dissertations and Projects
Research over the past decade suggests teachers have low instructional self-efficacy/confidence and more concerns about implementing inclusive teaching practices. This quantitative correlational study explored whether reported concerns and demographic variables (gender, age, education, and years of teaching experience) predicts teachers’ instructional self-efficacy with students with disabilities. The Concerns about Inclusive Education and the Teachers’ Efficacy in Implementing Inclusive Practices scales were administered to 123 K-12 classroom teachers in Georgia. Data were subjected to hierarchical linear multiple regression to examine whether systematically adding select demographic variables and teachers’ concern scores to the overall model significantly improved the model’s ability to predict …
Learning Loss In Passage Reading Fluency For Elementary Students During Covid-19 School Closure, David Neil Stone
Learning Loss In Passage Reading Fluency For Elementary Students During Covid-19 School Closure, David Neil Stone
Doctoral Dissertations and Projects
The onset of the COVID-19 pandemic in 2020 caused public schools across the United States to suddenly close and interrupt face-to-face instruction for all students for a sustained period of time. It remains uncertain the total effect of the prolonged closure on student learning. This study provides a historical research review of the effect of previous school closures, such as traditional summer breaks and explores the phenomenon of learning loss that occurs when instruction is paused. This causal-comparative study examined the effect on passage reading fluency and reading comprehension of fourth grade elementary students following an unprecedented 24-week disruption of …
A Phenomenological Study Of Trauma-Informed Teaching During A Global Education Disruption, Angelique Susan Smith
A Phenomenological Study Of Trauma-Informed Teaching During A Global Education Disruption, Angelique Susan Smith
Doctoral Dissertations and Projects
The purpose of this hermeneutical, phenomenological study described the experience of university educators using trauma-informed instructional practices during a global education disruption for university educators at Southeast University (pseudonym). The theory guiding this study is Richardson’s metatheory of resilience and resiliency (which describes an individual’s natural flow between homeostasis, through disruption, and adjunct to the disruption as part of the natural order of adaptation. The study addresses the following questions: How do university educators describe their experiences with trauma-informed teaching during a global education disruption? What formal strategies have university educators implemented to build social and emotional skills for students …
Clinical Opinion: The Diagnosis And Management Of Suspected Fetal Growth Restriction: An Evidence-Based Approach, Christoph C Lees, Roberto Romero, Tamara Stampalija, Andrea Dall'asta, Greggory A Devore, Federico Prefumo, Tiziana Frusca, Gerard H A Visser, John C Hobbins, Ahmet A Baschat, Caterina M Bilardo, Henry L Galan, Stuart Campbell, Dev Maulik, Francesc Figueras, Wesley Lee, Julia Unterscheider, Herbert Valensise, Fabricio Da Silva Costa, Laurent J Salomon, Liona C Poon, Enrico Ferrazzi, Giancarlo Mari, Giuseppe Rizzo, John C Kingdom, Torvid Kiserud, Kurt Hecher
Clinical Opinion: The Diagnosis And Management Of Suspected Fetal Growth Restriction: An Evidence-Based Approach, Christoph C Lees, Roberto Romero, Tamara Stampalija, Andrea Dall'asta, Greggory A Devore, Federico Prefumo, Tiziana Frusca, Gerard H A Visser, John C Hobbins, Ahmet A Baschat, Caterina M Bilardo, Henry L Galan, Stuart Campbell, Dev Maulik, Francesc Figueras, Wesley Lee, Julia Unterscheider, Herbert Valensise, Fabricio Da Silva Costa, Laurent J Salomon, Liona C Poon, Enrico Ferrazzi, Giancarlo Mari, Giuseppe Rizzo, John C Kingdom, Torvid Kiserud, Kurt Hecher
Faculty, Staff and Students Publications
This study reviewed the literature about the diagnosis, antepartum surveillance, and time of delivery of fetuses suspected to be small for gestational age or growth restricted. Several guidelines have been issued by major professional organizations, including the International Society of Ultrasound in Obstetrics and Gynecology and the Society for Maternal-Fetal Medicine. The differences in recommendations, in particular about Doppler velocimetry of the ductus venosus and middle cerebral artery, have created confusion among clinicians, and this review has intended to clarify and highlight the available evidence that is pertinent to clinical management. A fetus who is small for gestational age is …
Genetic Subtyping And Phenotypic Characterization Of The Immune Microenvironment And Myc/Bcl2 Double Expression Reveal Heterogeneity In Diffuse Large B-Cell Lymphoma, Zijun Y Xu-Monette, Li Wei, Xiaosheng Fang, Qingyan Au, Harry Nunns, Máté Nagy, Alexandar Tzankov, Feng Zhu, Carlo Visco, Govind Bhagat, Karen Dybkaer, April Chiu, Wayne Tam, Youli Zu, Eric D Hsi, Fredrick B Hagemeister, Xiaoping Sun, Xin Han, Heounjeong Go, Maurilio Ponzoni, Andrés J M Ferreri, Michael B Møller, Benjamin M Parsons, J Han Van Krieken, Miguel A Piris, Jane N Winter, Yong Li, Bing Xu, Maher Albitar, Hua You, Ken H Young
Genetic Subtyping And Phenotypic Characterization Of The Immune Microenvironment And Myc/Bcl2 Double Expression Reveal Heterogeneity In Diffuse Large B-Cell Lymphoma, Zijun Y Xu-Monette, Li Wei, Xiaosheng Fang, Qingyan Au, Harry Nunns, Máté Nagy, Alexandar Tzankov, Feng Zhu, Carlo Visco, Govind Bhagat, Karen Dybkaer, April Chiu, Wayne Tam, Youli Zu, Eric D Hsi, Fredrick B Hagemeister, Xiaoping Sun, Xin Han, Heounjeong Go, Maurilio Ponzoni, Andrés J M Ferreri, Michael B Møller, Benjamin M Parsons, J Han Van Krieken, Miguel A Piris, Jane N Winter, Yong Li, Bing Xu, Maher Albitar, Hua You, Ken H Young
Faculty, Staff and Students Publications
PURPOSE: Diffuse large B-cell lymphoma (DLBCL) is molecularly and clinically heterogeneous, and can be subtyped according to genetic alterations, cell-of-origin, or microenvironmental signatures using high-throughput genomic data at the DNA or RNA level. Although high-throughput proteomic profiling has not been available for DLBCL subtyping, MYC/BCL2 protein double expression (DE) is an established prognostic biomarker in DLBCL. The purpose of this study is to reveal the relative prognostic roles of DLBCL genetic, phenotypic, and microenvironmental biomarkers.
EXPERIMENTAL DESIGN: We performed targeted next-generation sequencing; IHC for MYC, BCL2, and FN1; and fluorescent multiplex IHC for microenvironmental markers in a large cohort of …
Visual Pigment-Deficient Cones Survive And Mediate Visual Signaling Despite The Lack Of Outer Segments, Hui Xu, Nange Jin, Jen-Zen Chuang, Zhao Zhang, Xiaoyue Zhong, Zhijing Zhang, Ching-Hwa Sung, Christophe P Ribelayga, Yingbin Fu
Visual Pigment-Deficient Cones Survive And Mediate Visual Signaling Despite The Lack Of Outer Segments, Hui Xu, Nange Jin, Jen-Zen Chuang, Zhao Zhang, Xiaoyue Zhong, Zhijing Zhang, Ching-Hwa Sung, Christophe P Ribelayga, Yingbin Fu
Faculty, Staff and Students Publications
Rhodopsin and cone opsins are essential for light detection in vertebrate rods and cones, respectively. It is well established that rhodopsin is required for rod phototransduction, outer segment disk morphogenesis, and rod viability. However, the roles of cone opsins are less well understood. In this study, we adopted a loss-of-function approach to investigate the physiological roles of cone opsins in mice. We showed that cones lacking cone opsins do not form normal outer segments due to the lack of disk morphogenesis. Surprisingly, cone opsin-deficient cones survive for at least 12 mo, which is in stark contrast to the rapid rod …
The Impact Of Response To Iron Therapy On Maternal And Neonatal Outcomes Among Pregnant Women With Anemia, Sarah E Detlefs, Michael D Jochum, Bahram Salmanian, Jennifer R Mckinney, Kjersti M Aagaard
The Impact Of Response To Iron Therapy On Maternal And Neonatal Outcomes Among Pregnant Women With Anemia, Sarah E Detlefs, Michael D Jochum, Bahram Salmanian, Jennifer R Mckinney, Kjersti M Aagaard
Faculty, Staff and Students Publications
BACKGROUND: Anemia during pregnancy is associated with increased risks of preterm birth, preeclampsia, cesarean delivery, and maternal morbidity. The most prevalent modifiable cause of pregnancy-associated anemia is iron deficiency. However, it is still unclear whether iron therapy can reduce the risks of adverse outcomes in women with anemia.
OBJECTIVE: This study aimed to determine whether response to iron therapy among women with anemia is associated with a change in odds of adverse maternal and neonatal outcomes.
STUDY DESIGN: This was a population-based cohort study (2011-2019) using an institutional database composed of obstetrical patients from 2 delivery hospitals. Patients with adequate …
Identifying Causative Microorganisms In Left Ventricular Assist Device Infections As A Guide For Developing Bacteriophage Therapy, Ishan Kamat, Harveen Lamba, Casey Hines-Munson, Samuel Hudson, Kenneth Liao, Kenneth L Muldrew, Sabrina Green, Austen Terwilliger, Heidi B Kaplan, Robert F Ramig, Anthony Maresso, Barbara W Trautner
Identifying Causative Microorganisms In Left Ventricular Assist Device Infections As A Guide For Developing Bacteriophage Therapy, Ishan Kamat, Harveen Lamba, Casey Hines-Munson, Samuel Hudson, Kenneth Liao, Kenneth L Muldrew, Sabrina Green, Austen Terwilliger, Heidi B Kaplan, Robert F Ramig, Anthony Maresso, Barbara W Trautner
Faculty, Staff and Students Publications
BACKGROUND: As more left ventricular-assist devices (LVADs) are implanted, multidrug-resistant LVAD infections are becoming increasingly common, partly due to bacterial biofilm production. To aid in developing bacteriophage therapy for LVAD infections, we have identified the most common bacterial pathogens that cause LVAD driveline infections (DLIs) in our heart transplant referral center.
MATERIALS AND METHODS: We studied a retrospective cohort of patients who received LVADs from November 2003 to August 2017 to identify the common causative organisms of LVAD infection. We also studied a prospective cohort of patients diagnosed with DLIs from October 2018 to May 2019 to collect bacterial strains …
P16 Represses Dna Damage Repair Via A /Novel Ubiquitin-Dependent Signaling Cascade, David P Molkentine, Jessica M Molkentine, Kathleen A Bridges, David R Valdecanas, Annika Dhawan, Reshub Bahri, Andrew J Hefner, Manish Kumar, Liangpeng Yang, Mohamed Abdelhakiem, Phillip M Pifer, Vlad Sandulache, Aakash Sheth, Beth M Beadle, Howard D Thames, Kathryn A Mason, Curtis R Pickering, Raymond E Meyn, Heath D Skinner
P16 Represses Dna Damage Repair Via A /Novel Ubiquitin-Dependent Signaling Cascade, David P Molkentine, Jessica M Molkentine, Kathleen A Bridges, David R Valdecanas, Annika Dhawan, Reshub Bahri, Andrew J Hefner, Manish Kumar, Liangpeng Yang, Mohamed Abdelhakiem, Phillip M Pifer, Vlad Sandulache, Aakash Sheth, Beth M Beadle, Howard D Thames, Kathryn A Mason, Curtis R Pickering, Raymond E Meyn, Heath D Skinner
Faculty, Staff and Students Publications
Squamous cell carcinoma driven by human papillomavirus (HPV) is more sensitive to DNA-damaging therapies than its HPV-negative counterpart. Here, we show that p16, the clinically used surrogate for HPV positivity, renders cells more sensitive to radiotherapy via a ubiquitin-dependent signaling pathway, linking high levels of this protein to increased activity of the transcription factor SP1, increased HUWE1 transcription, and degradation of ubiquitin-specific protease 7 (USP7) and TRIP12. Activation of this pathway in HPV-positive disease led to decreased homologous recombination and improved response to radiotherapy, a phenomenon that can be recapitulated in HPV-negative disease using USP7 inhibitors in clinical development. This …
Functional And Conformational Plasticity Of An Animal Group 1 Lea Protein, Brett Janis, Clinton Belott, Tyler Brockman, Michael Menze
Functional And Conformational Plasticity Of An Animal Group 1 Lea Protein, Brett Janis, Clinton Belott, Tyler Brockman, Michael Menze
Faculty and Staff Scholarship
Group 1 (Dur-19, PF00477, LEA_5) Late Embryogenesis Abundant (LEA) proteins are present in organisms from all three domains of life, Archaea, Bacteria, and Eukarya. Surprisingly, Artemia is the only genus known to include animals that express group 1 LEA proteins in their desiccation-tolerant life-history stages. Bioinformatics analysis of circular dichroism data indicates that the group 1 LEA protein AfLEA1 is surprisingly ordered in the hydrated state and undergoes during desiccation one of the most pronounced disorder-to-order transitions described for LEA proteins from A. franciscana. The secondary structure in the hydrated state is dominated by random coils (42%) and β-sheets (35%) …
Ngos And States Of Aging: Ngo As Male/Culture Advocates And As Female/Nature Caregivers, Alexandra Crampton
Ngos And States Of Aging: Ngo As Male/Culture Advocates And As Female/Nature Caregivers, Alexandra Crampton
Social and Cultural Sciences Faculty Research and Publications
No abstract provided.
March 2022 News Releases, University Of Montana--Missoula. Office Of University Relations
March 2022 News Releases, University Of Montana--Missoula. Office Of University Relations
University of Montana News Releases, 1928, 1956-present
No abstract provided.
Effect Of Incorporation Of Hydroxyapatite Nanorods In Self-Etch Adhesive On Microtensile Bond Strength And Micromorphological Patterns Of Resin/Dentin Interface, Hameed K. Musa, Hamdi H. Hammama, Salah H. Mahmoud
Effect Of Incorporation Of Hydroxyapatite Nanorods In Self-Etch Adhesive On Microtensile Bond Strength And Micromorphological Patterns Of Resin/Dentin Interface, Hameed K. Musa, Hamdi H. Hammama, Salah H. Mahmoud
Mansoura Journal of Dentistry
Objective: To evaluate microtensile bond strength (μTBS) of four types of adhesives including the “modified-bioactive” and their effect on micromorphological patterns of resin/dentin interface, immediately after 24hours and after 6months storage, followed by thermocycling. Material and Methods: Eighty extracted sound permanent molars were collected from patients seeking extraction in the outpatient clinic oral surgery department, Faculty of Dentistry at Mansoura University, according to the regulation of our institutional ethical committee under # (A03160321). The selected molars were assigned into four groups according to adhesive types: non-modified self-etch adhesive modified self-etch adhesive with hydroxyapatite nanorods, universal adhesive, resin-modified glass ionomer adhesive. …
Effect Of Platelet Based Preparation On Orthodontic Tooth Movement In Rabbits, Salma A. Mahmoud, Ahmed M. Fouda, Mohammed E. Grawish, Yasser L. Abdelnaby
Effect Of Platelet Based Preparation On Orthodontic Tooth Movement In Rabbits, Salma A. Mahmoud, Ahmed M. Fouda, Mohammed E. Grawish, Yasser L. Abdelnaby
Mansoura Journal of Dentistry
Objective: Autologous Platelet rich plasma (PRP) is used to accelerate orthodontic tooth movement, but its effect is still controversial. Materials and Methods: Twenty-eight male white Vienna rabbits were divided randomly into two main groups control and PRP. Each group included fourteen rabbits. Tooth movement was measured in seven rabbits from each group after 3 and 14 days respectively. Orthodontic tooth movement was generated by closed coil spring ligated between the mandibular first premolar and mandibular central incisors on both sides. The tooth movement was measured by measuring the space between mandibular first and second premolar using an orthodontic gauge and …
The Nine-Item Internet Gaming Disorder Scale (Igds9-Sf): Its Psychometric Properties Among Sri Lankan Students And Measurement Invariance Across Sri Lanka, Turkey, Australia, And The Usa, Amira Mohammed Ali, Rasmieh Al-Amer, Maha Atout, Tazeen Saeed Ali, Ayman M Hamdan Mansour, Haitham Khatatbeh, Abdulmajeed A. Alkhamees, Amin Omar Hendawy
The Nine-Item Internet Gaming Disorder Scale (Igds9-Sf): Its Psychometric Properties Among Sri Lankan Students And Measurement Invariance Across Sri Lanka, Turkey, Australia, And The Usa, Amira Mohammed Ali, Rasmieh Al-Amer, Maha Atout, Tazeen Saeed Ali, Ayman M Hamdan Mansour, Haitham Khatatbeh, Abdulmajeed A. Alkhamees, Amin Omar Hendawy
School of Nursing & Midwifery
The prevalence of internet gaming disorders (IGD) is considerably high among youth, especially with the social isolation imposed by the ongoing COVID-19 pandemic. IGD adversely affects mental health, quality of life, and academic performance. The Internet Gaming Disorder Scale (IGDS9-SF) is designed to detect IGD according to DSM-IV diagnostic criteria. However, inconsistent results are reported on its capacity to diagnose IGD evenly across different cultures. To ensure the suitability of the IGDS9-SF as a global measure of IGD, this study examined the psychometric properties of the IGDS9-SF in a sample of Sri Lankan university students (N = 322, mean age …
Genetically Engineered Food, Food Security, And Climate Change, Joanna K. Sax
Genetically Engineered Food, Food Security, And Climate Change, Joanna K. Sax
The Business, Entrepreneurship & Tax Law Review
Malnutrition is the leading cause of death and disease worldwide. Climate change is an existential crisis. We need to feed people and address the role of agriculture in climate change – at the same time. This is problematic, as agriculture inherently creates issues that contributes to climate change. Utilizing science, through genetically engineered crops, is one way to close the harm gap between food security and climate change. This essay addresses the controversial issue of genetically engineered crops with the complicated issues of food security and cli-mate change by analyzing three main issues: (1) how the science of genetically engineered …
2022-March-01-Etsu Ranked By Forbes Among Americas Best Employers, University Marketing And Communication, East Tennessee State University
2022-March-01-Etsu Ranked By Forbes Among Americas Best Employers, University Marketing And Communication, East Tennessee State University
ETSU News
JOHNSON CITY, Tenn. – East Tennessee State University has been recognized by Forbes in its 2022 listing of America’s Best Employers.
The listing on Forbes.com was compiled by Forbes and Statista based on data from an independent survey taken by approximately 60,000 employees working for companies with more than 1,000 workers in the United States. The evaluation was based on direct and indirect recommendations from respondents who were asked to rate their willingness to recommend their own employer to friends and family.
In total, 1,000 employers were recognized across 25 different industry sectors. The list is divided into two rankings: …
2022-March-01-Etsu Scientist Playing On A Global Stage, University Marketing And Communication, East Tennessee State University
2022-March-01-Etsu Scientist Playing On A Global Stage, University Marketing And Communication, East Tennessee State University
ETSU News
JOHNSON CITY, Tenn. (March 2022) – Late last month, Dr. Aruna Kilaru wrote a piece aimed at addressing food insecurity and climate change using agricultural biotechnology.
Suggesting how both farmers and government agencies can work together to reduce harmful emissions and minimize food waste, the article appeared as part of her work as a science, technology and policy fellow of the American Association for the Advancement of Science, and science adviser and international trade policy officer for the U.S. Department of Agriculture’s Foreign Agricultural Service, New Technologies and Production Methods Divisions.
Dr. Aruna Kilaru
It means that Kilaru, a professor …