Digital Commons Network^™

Visible/Near Infrared (Vis/Nir) Spectroscopy And Multivariate Data Analysis (Mvda) For Identification And Quantification Of Olive Leaf Spot (Ols) Disease, Nawaf Abukhalaf, Mazen Salman

Palestine Technical University Research Journal

Early detection of plant disease requires usually elaborating methods techniques and especially when symptoms are not visible. Olive Leaf Spot (OLS) infecting upper surface of olive leaves has a long latent infection period. In this work, VIS/NIR spectroscopy was used to determine the latent infection and severity of the pathogens. Two different classification methods were used, Partial Least Squared-Discrimination Analysis (PLS-DA) (linear method) and Support Vector Machine (SVM) (non-linear). SVM-classification was able to classify severity levels 0, 1, 2, 3, 4, and 5 with classification rates of 94, 90, 73, 79, 83 and 100%, respectively The overall classification rate was …

Effects Of Passive And Active Leg Movements To Interrupt Sitting In Mild Hypercapnia On Cardiovascular Function In Healthy Adults, Song-Young Park, Tesean Wooden, Elizabeth J. Pekas, Santosh K. Yadav, Dustin Slivka, Gwenael Layec

Health and Kinesiology Faculty Publications

Prolonged sitting in a mild hypercapnic environment impairs peripheral vascular function. The effects of sitting interruptions using passive or active skeletal muscle contractions are still unclear. Therefore, we sought to examine the vascular effects of brief periods (2 min every half hour) of passive and active lower limb movement to interrupt prolonged sitting with mild hypercapnia in adults. Fourteen healthy adults (24 ± 2 yr) participated in three experimental visits sitting for 2.5 h in a mild hypercapnic environment (CO2 = 1,500 ppm): control (CON, no limb movement), passive lower limb movement (PASS), and active lower limb movement (ACT) during …

The Effect Of Task And Environment Constraints On Aquatic Locomotor Behavior: Qualitative Data Analysis, Ernani Xavier Filho, Edison J. Manoel

International Journal of Aquatic Research and Education

Many constraints (environmental, organismic, and task) act on all patterns of motor coordination, although their effects on swimming is less well understood. To this end, we carried out the current study with fifty-six participants, ages ranging from six to twelve years. The experimental tasks were created from the original task in which changes in task speed and environmental context were manipulated. Four aspects in the results were notable: a) a main trend was one of performance with the same developmental status among the tasks; b) when behaviour changed, this occurred due to environmental constraints, leading to more rudimentary patterns of …

Trauma-Informed Care In The Emergency Department, Kayla Kvell, Kristin Oscarson

Nursing DNP Projects

Introduction: This project aims to analyze the effectiveness of trauma-informed care (TIC) education on attitudes of registered nurses (RNs) and psychiatric associates (PAs) towards TIC. The purpose of this project was to educate ED (emergency department) RNs and PAs on the effects of trauma and increase attitudes towards implementing a TIC approach to care for mental health (MH) patients in the ED.

Method: This project followed a pre–post-survey design with quantitative data. Participants included RNs and PAs newly hired to the ED, and/or if they had no previous TIC education. Data were collected utilizing a 10-question Likert scale survey.

Results: …

Physics Alumni Newsletter Spring 2022, Terry Goforth

Physics Alumni Newsletter

Physics Alumni Newsletter

The Physics Alumni Newsletter is produced by the SWOSU Physics Department.

Our Engineering Physics students are recruited in fields such as electronics, aerospace, mechanical engineering, petroleum engineering and software engineering. Graduates also have careers in meteorology, architecture, education and more.

Functional Replacement Of Myostatin With Gdf-11 In The Germline Of Mice., Se-Jin Lee, Adam Lehar, Renata Rydzik, Daniel W Youngstrom, Shalender Bhasin, Yewei Liu, Emily L Germain-Lee

Faculty Research 2022

BACKGROUND: Myostatin (MSTN) is a transforming growth factor-ß superfamily member that acts as a major regulator of skeletal muscle mass. GDF-11, which is highly related to MSTN, plays multiple roles during embryonic development, including regulating development of the axial skeleton, kidneys, nervous system, and pancreas. As MSTN and GDF-11 share a high degree of amino acid sequence identity, behave virtually identically in cell culture assays, and utilize similar regulatory and signaling components, a critical question is whether their distinct biological functions result from inherent differences in their abilities to interact with specific regulatory and signaling components or whether their distinct …

Full Issue - Leadership

Journal of Nonprofit Innovation

“Leadership is all about changing the order of things. Machiavelli said, ‘There is nothing so difficult or so dangerous as to undertake to change the order of things.’ And that is true. It is difficult, and it is sometimes dangerous, because people resist and people are afraid. And that is why only leaders can drive change.”

“Management is the production of acceptable results within known constraints and conditions; very important. But management is not leadership.” https://ecorner.stanford.edu/videos/the-difference-between-management-and-leadership/,

Taken From Carly Fiorina, Former CEO, HP, Speech from Stanford eCorner

Divergent Metabolic Effects Of Metformin Merge To Enhance Eicosapentaenoic Acid Metabolism And Inhibit Ovarian Cancer In Vivo, Mary P. Udumula, Laila M. Poisson, Indrani Datta, Nivedita Tiwari, Seongho Kim, Jasdeep Chinna-Shankar, Ghassan Allo, Sharif Sakr, Miriana Hijaz, Adnan R. Munkarah, Shailendra Giri, Ramandeep Rattan

Obstetrics, Gynecology and Women's Health Services Articles

Metformin is being actively repurposed for the treatment of gynecologic malignancies including ovarian cancer. We investigated if metformin induces analogous metabolic changes across ovarian cancer cells. Functional metabolic analysis showed metformin caused an immediate and sustained decrease in oxygen consumption while increasing glycolysis across A2780, C200, and SKOV3ip cell lines. Untargeted metabolomics showed metformin to have differential effects on glycolysis and TCA cycle metabolites, while consistent increased fatty acid oxidation intermediates were observed across the three cell lines. Metabolite set enrichment analysis showed alpha-linolenic/linoleic acid metabolism as being most upregulated. Downstream mediators of the alpha-linolenic/linoleic acid metabolism, eicosapentaenoic acid (EPA) …

Struggling To Make Good: The Dilemmas Of Fatherhood For Formerly Incarcerated African-American Men, Francis Prior, Steven Farough

Qualitative Criminology (QC)

While some have argued that absent low socioeconomic status black fathers are to blame for urban crime and poverty, others have highlighted how mass incarceration disproportionately separates low socioeconomic status black fathers from their children. Less frequently heard and acknowledged in the public conversations about low socioeconomic status black fatherhood and mass incarceration are the voices of those same fathers who have been impacted by the system. How do formerly incarcerated black fathers view their role as fathers? Based on 30 interviews of formerly incarcerated black men recruited from a prisoner reentry organization in a large northeastern city in the …

Re-Evaluation Of The Fijianolide/Laulimalide Chemotype Suggests An Alternate Mechanism Of Action For C-15/C-20 Analogs., Joseph D. Morris, Leila Takahashi-Ruiz, Lauren N. Persi, Jonathan C. Summers, Erin P. Mccauley, Peter Y. W. Chan, Gabriella Amberchan, Itzel Lizama-Chamu, David A. Coppage, Phillip Crews, April L. Risinger, Tyler A. Johnson

Natural Sciences and Mathematics | Faculty Scholarship

Herein, we report on naturally derived microtubule stabilizers with activity against triple negative breast cancer (TNBC) cell lines, including paclitaxel, fijianolide B/laulimalide (3), fijianolide B di-acetate (4), and two new semisynthetic analogs of 3, which include fijianolide J (5) and fijianolide L (6). Similar to paclitaxel, compound 3 demonstrated classic microtubule stabilizing activity with potent (GI50 = 0.7–17 nM) antiproliferative efficacy among the five molecularly distinct TNBC cell lines. Alternatively, compounds 5 or 6, generated from oxidation of C-20 or C-15 and C-20 respectively, resulted in a unique profile with …

Emerge Institute Field Safety & Logistics Handbook, Sophia A. Burke, Ruth Varner, Virginia Rich, Emerge 2021 Field Team

All Materials

The EMERGE Institute, a NSF-funded Biology Integration Institute, consists of over ninety participants at varying career stages and disciplines from universities around the globe. The central aim of EMERGE is to investigate the EMergent Ecosystem Response to ChanGE in the model peatland ecosystem Stordalen Mire, located in subarctic Sweden using a broad sweep of scientific sampling and analytical techniques. EMERGE uses a multi-pronged approach to foster an inclusive transdisciplinary research environment for all EMERGE participants through mentorship and training.

Annual fieldwork campaigns to Stordalen Mire, a semi-remote field site in northern Sweden, are an …

Bigmouth: Development And Maintenance Of A Successful Dental Data Repository, Muhammad F Walji, Heiko Spallek, Krishna Kumar Kookal, Jane Barrow, Britta Magnuson, Tamanna Tiwari, Udochukwu Oyoyo, Michael Brandt, Brian J Howe, Gary C Anderson, Joel M White, Elsbeth Kalenderian

Faculty, Staff and Student Publications

Few clinical datasets exist in dentistry to conduct secondary research. Hence, a novel dental data repository called BigMouth was developed, which has grown to include 11 academic institutions contributing Electronic Health Record data on over 4.5 million patients. The primary purpose for BigMouth is to serve as a high-quality resource for rapidly conducting oral health-related research. BigMouth allows for assessing the oral health status of a diverse US patient population; provides rationale and evidence for new oral health care delivery modes; and embraces the specific oral health research education mission. A data governance framework that encouraged data sharing while controlling …

Programs Committee Approved Programs 3/15/22, Angela Brock

Programs Committee (PC)

No abstract provided.

Principles And Applications Of Crispr Toolkit In Virus Manipulation, Diagnosis, And Virus-Host Interactions, Saleh Jamehdor, Sara Pajouhanfar, Sadaf Saba, Georges Uzan, Ali Teimoori, Sina Naserian

Open Access Publications

Viruses are one of the most important concerns for human health, and overcoming viral infections is a worldwide challenge. However, researchers have been trying to manipulate viral genomes to overcome various disorders, including cancer, for vaccine development purposes. CRISPR (clustered regularly interspaced short palindromic repeats) is becoming one of the most functional and widely used tools for RNA and DNA manipulation in multiple organisms. This approach has provided an unprecedented opportunity for creating simple, inexpensive, specific, targeted, accurate, and practical manipulations of viruses, such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), human immunodeficiency virus-1 (HIV-1), and vaccinia virus. Furthermore, …

Trends In Scientific Output On The Lesbian, Gay, Bisexual, And Transgender (Lgbt) Community Research: A Bibliometric Analysis Of The Literature, David An, Kavita Batra

School of Medicine Faculty Research

Introduction: Lesbian, Gay, Bisexual, and Transgender (LGBT) represent a diverse group with special needs due to the unusual developmental experiences and social inequalities. This paper aims to explore and outline a future research direction in LGBT issues through tracing our historical understanding of this population from an aspect of scientific research. Methods: LGBT-related peer-reviewed documents were retrieved from the PubMed database and the study period was set from the inception to 2021. Python-based methods were then performed to analyze the publication metadata and extract the most prominent research topics based on the abstract contents. Key points covered in the study …

Student Senate Meeting Minutes March 15, 2022, Student Senate-Winona State University

Student Senate Meeting Minutes

This document is the official Winona State University Student Senate Minutes March 15, 2022.

Metronidazole Treatment Rapidly Reduces Genital Inflammation Through Effects On Bacterial Vaginosis-Associated Bacteria Rather Than Lactobacilli, Eric Armstrong, Hilary Reno, Et Al.

2020-Current year OA Pubs

BackgroundBacterial vaginosis (BV) causes genital inflammation and increases HIV risk, whereas a vaginal microbiota dominated by Lactobacillus species is associated with immune quiescence and relative HIV protection. BV treatment reduces genital inflammation, but it is unclear whether this reduction is driven by a decrease in BV-associated bacteria or an increase in Lactobacillus species.METHODSTo evaluate the short-term effect of standard BV treatment on genital immunology and the vaginal microbiota, vaginal swabs were collected immediately before and after metronidazole treatment for BV and analyzed with multiplex ELISA, metagenomic sequencing, and quantitative PCR.RESULTSTopical metronidazole treatment rapidly reduced vaginal levels of proinflammatory cytokines, chemokines, …

Machines, Intimacy Topics For Two Hybrid Oxford Science Cafes, Edwin B. Smith

University of Mississippi News

Computer science, neuroscience professors to present during in-person and virtual events

Improving Capture Methods For Neonate Ungulates, Matthew T. Turnley

Theses and Dissertations

The capture of neonate ungulates has played an integral role in studies of habitat selection, phenology, survival, and other topics of ecological interest. However, neonates can be difficult for researchers to locate and capture. Neonate ungulates are born in habitats with reduced visibility, frequently spend time in a concealed, prone position, and may display cryptic coloration. In an attempt to improve researchers' likelihood of locating and capturing neonate ungulates, multiple capture methods have been developed. Much remains unknown about biases associated with capture methods and how to further improve capture methods once biases are understood. Our objectives were to determine …

The Experiences And Expressions Of Compassion Among Critical Care Nurses, Mark S. Walker

Dissertations

Compassion is a core attribute of nursing practice and is associated with improved patient satisfaction and outcomes. For the last several decades, nurse researchers have been focused on the concept of compassion fatigue. Only recently has compassion appeared in nursing literature. Therefore, the purpose of this study was to explore the experiences and expressions of compassion among critical care nurses.

This dissertation includes a literature review of compassion within nursing education and practice, how it is currently defined, and a review of the empirical data. Next, two interpretative phenomenological qualitative studies were conducted. One study explored the experiences of compassion …

Landscape Of Molecular Crosstalk Perturbation Between Lung Cancer And Covid-19, Aditi Kuchi, Jiande Wu, Jyotsna Fuloria, Chindo Hicks

School of Medicine Faculty Publications

Background: Lung cancer patients have the worst outcomes when affected by coronavirus disease 2019 (COVID-19). The molecular mechanisms underlying the association between lung cancer and COVID-19 remain unknown. The objective of this investigation was to determine whether there is crosstalk in molecular perturbation between COVID-19 and lung cancer, and to identify a molecular signature, molecular networks and signaling pathways shared by the two diseases. Methods: We analyzed publicly available gene expression data from 52 severely affected COVID-19 human lung samples, 594 lung tumor samples and 54 normal disease-free lung samples. We performed network and pathways analysis to identify molecular networks …

Programs Committee Agenda 3/15/22, Angela Brock

Programs Committee (PC)

No abstract provided.

The Relationship Between Eating Behaviors And Weight Cycling Among College Students, Kayla Valluzzi

Theses and Dissertations

Purpose The aim of this study was to investigate the factors that contribute to diet and weight control behaviors and the presence of weight cycling among college students.

Study Design Students at Illinois State University were invited to participate in a Qualtrics survey distributed via email. Inclusion criteria included being a current student at the university between the ages of 18 and 24. The study population (N= 351) included participants with an average age of 20.5 years old (SD= 1.7). Preferred gender included 267 (76.1%) females, 75 (21.4%) males and 9 (2.6%) non-binary identities.

Results The majority of participants were …

2022-March-15-Help Name New Bald Eagle, University Marketing And Communication, East Tennessee State University

ETSU News

JOHNSON CITY, Tenn. (March 15, 2022) – For nearly a decade, East Tennessee State University has livestreamed active American bald eagle nests in Johnson City. 

Now, you can help name one of the new female eagles.  

Officials at ETSU have narrowed the suggested names, submitted by nearly 500 viewers in recent weeks, for the female eagle Boone has chosen as his mate.   

Vote at surveymonkey.com/r/ZLK7HBP. The contest closes on Sunday, March 20, at 11:59 p.m.

Here’s a look at the names that voters may choose from: Becca, Becky, Bella, Dani, Danyelle, Dolly, Fancy, Jolene, Rebecca and Tanasi. Earlier this …

The Life History Of Drosophila Sperm Involves Molecular Continuity Between Male And Female Reproductive Tracts, Erin L. Mccullough, Emma Whittington, Akanksha Singh, Scott Pitnick, Mariana F. Wolfner, Steve Dorus

Biology

Interactions between sperm and the female reproductive tract (FRT) are critical to reproductive success and yet are poorly understood. Because sperm complete their functional maturation within the FRT, the life history of sperm is likely to include a molecular “hand-off” from males to females. Although such intersexual molecular continuity is likely to be widespread among all internally fertilizing species, the identity and extent of female contributions are largely unknown. We combined semiquantitative proteomics with sex-specific isotopic labeling to catalog the posttesticular life history of the sperm proteome and determine the extent of molecular continuity between male and FRTs. We show …

Le Gout Qui Reste: Cultural Identity And Belonging In Ook Chung's Kimchi, Taurean James Weber-Laurencio

Dissertations and Theses

The emphasis placed on the questioning of identity in Québécois society since the Quiet Revolution of the mid-twentieth century continues to this day. Whereas this search for a specifically Québécois identity was originally cast in terms of an Anglophone/Francophone divide, the influx of migrants from around the world to the province since the 1970s has rendered such a simplistic, binary discourse impossible. The population of Québéc in general and of Montréal in particular is now multicultural; visible minorities now constitute twenty-six percent of the Montréal populace. While most migrants in Québéc are able to find a niche in Montréal in …

Repurposing Lansoprazole And Posaconazole To Treat Leishmaniasis: Integration Of In Vitro Testing, Pharmacological Corroboration, And Mechanisms Of Action, Yash Gupta, Steven Goicoechea, Jesus G. Romero, Raman Mathur, Thomas R. Caulfield, Daniel P. Becker, Ravi Durvasula, Prakasha Kempaiah

Chemistry: Faculty Publications and Other Works

Leishmaniasis remains a serious public health problem in many tropical regions of the world. Among neglected tropical diseases, the mortality rate of leishmaniasis is second only to malaria. All currently approved therapeutics have toxic side effects and face rapidly increasing resistance. To identify existing drugs with antileishmanial activity and predict the mechanism of action, we designed a drug-discovery pipeline utilizing both in-silico and in-vitro methods. First, we screened compounds from the Selleckchem Bio-Active Compound Library containing ~1622 FDA-approved drugs and narrowed these down to 96 candidates based on data mining for possible anti-parasitic properties. Next, we completed preliminary in-vitro testing …

Ucc Minutes 3/15/22, Angela Brock

UCC Agendas/Minutes

No abstract provided.

American Heart Association's Life's Simple 7: Lifestyle Recommendations, Polygenic Risk, And Lifetime Risk Of Coronary Heart Disease, Natalie R Hasbani, Symen Ligthart, Michael R Brown, Adam S Heath, Allison Bebo, Kellan E Ashley, Eric Boerwinkle, Alanna C Morrison, Aaron R Folsom, David Aguilar, Paul S De Vries

Faculty, Staff and Students Publications

BACKGROUND: Understanding the effect of lifestyle and genetic risk on the lifetime risk of coronary heart disease (CHD) is important to improving public health initiatives. Our objective was to quantify remaining lifetime risk and years free of CHD according to polygenic risk and the American Heart Association's Life's Simple 7 (LS7) guidelines in a population-based cohort study.

METHODS: Our analysis included data from participants of the ARIC (Atherosclerosis Risk in Communities) study: 8372 White and 2314 Black participants; 45 years of age and older; and free of CHD at baseline examination. A polygenic risk score (PRS) comprised more than 6 …

Modeling Cyanobacteria Vertical Migration, Corina Christina Mae Overman, Scott A. Wells

Civil and Environmental Engineering Faculty Publications and Presentations

Cyanobacteria often cause harmful algal blooms and release toxic substances that can harm humans and animals. Accurately modeling these phytoplankton is a step towards predicting, preventing, and controlling such blooms. Certain cyanobacteria species are known to migrate vertically in the water column on a daily cycle. Capturing this behavior is one aspect of modeling their dynamics. Previous studies on modeling cyanobacterial vertical migration are reviewed and summarized. Several models of cyanobacteria vertical movement are tested using data from field studies. These models are applied using both continuum and particle-tracking frameworks. Models range in complexity from simple functions of time to …