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Senstive Enantiomeric Analysis Of N-Acyl Homoserine Lactones In Bacterial Matrices, Abiud E. Portillo

Chemistry & Biochemistry Dissertations - Archive

Communication between unicellular organism has long been studied with many facets yet to be discovered. A specific type of communication in gram-negative bacteria is quorum sensing (QS). N-acyl homoserine lactones (N-HLs) are the molecular signals in this process. At a critical concentration of N-HLs, all bacteria of the same population stop behaving like individuals and in a concerted manner induce a specific gene expression which ultimately benefits the entire population in major. This phenomenon has been coined with the term quorum sensing with the main signaling molecules dubbed L-N-acyl homoserine lactones (L-N-HL). Quorum sensing signaling pathways have their influence in …

Investigating The Frictional Properties Of Organic Matter And Pore Structure Of Organic-Rich Shales With Atomic Force Microscopy And Scanning Electron Microscopy, Farnood Sobhbidari

Earth & Environmental Sciences Dissertations - Archive

Understanding geomechanical properties of shales, such as stiffness properties and fracture toughness, is important in different areas of petroleum industry-related activities including fracturing efficiency, petroleum flow to the wellbores, and induced seismicity. Nanoscale to microscale experiments on shale samples require a much smaller sample compared to macroscale experiments. This is a major advantage because irregularly-shaped drill cuttings from shales can be used for experimental analyses, such as nanoindentation or atomic force microscopy (AFM). However, a characterization of mechanical properties at the nano- to micro-scale is a relatively new addition to classical geomechanical experiments on shales, and there is still lack …

Federal Food Safety Framework: Where Does Seaweed Fit In?, Catherine M. Janasie

Journal of Food Law & Policy

When one mentions seaweed as food, what do you think of? The dried nori used to wrap your sushi roll or perhaps the seaweed salad on the side? In fact, seaweed has many uses, including as both a food source in its own right and as a food additive. While the seaweed market has been dominated by East Asian countries, seaweed is cultivated in about 50 countries, and the U.S. seaweed industry is steadily growing. The global seaweed industry is currently worth about $6 billion annually. Food products for human consumption account for about 85% of this value.

Following The Framework: Intentional Genomic Alterations In Animals, Sarah Copper

Journal of Food Law & Policy

Intentional genomic alterations in animals or genetically engineered animals have existed in their modern form since the 1980s. However, the introduction of these animals into our food supply has been a more recent development. The federal government has taken steps in an attempt to regulate these products in a streamlined and efficient manner but has faced criticism in their approach. While the Food and Drug Administration (“FDA”) is currently responsible for the regulation of intentional genomic alterations (“IGAs”) in animals, there is significant effort behind transferring that oversight to the United States Department of Agriculture (“USDA”). However, in the meantime, …

Heavy Metals As Risk Factors For Human Diseases - A Bayesian Network Approach, M Perrelli, R Wu, D J Liu, R G Lucchini, L Del Bosque-Plata, Michael Vergare, M P Akhter, J Ott, Claudia Gragnoli

Division of Endocrinology, Diabetes and Metabolic Diseases Faculty Papers

Modern industrial agricultural processes expose human beings to multifactorial environmental pollution including heightened levels of heavy metals. The effects of acute heavy metal exposures at toxic levels are usually known; they are tested for and treated promptly. The effects of low/moderate-level chronic heavy metal exposures are less known as they may be subclinical, and pathogenic effects may only manifest clinically over time under the disguise of a diagnosable disease or miscellaneous symptoms attributed to aging. Consequently, the health impact of low-moderate heavy metal exposure is unlikely to be identified. Furthermore, established heavy metal safety levels often fail to recognize the …

Presenting The Afriarch Isotopic Database, Steven Goldstein, Sean Hixon, Erin Scott, Jesse Wolfhagen, Victor Iminjili, Anneke Janzen, Kendra Chritz, Elizabeth Sawchuk, Emmanuel Ndiema, Judith C. Sealy, Abigail Stone, Gretchen Zoeller, Leanne N. Phelps, Ricardo Fernandes

Faculty Publications – Sociology and Anthropology

AfriArch is an archaeological and paleoenvironmental data community designed to integrate datasets related to human-environmental interactions in Holocene Africa. Here we present a dataset of bioarchaeological stable isotope (C/N/O) and radiocarbon measurements from African archaeological sites spanning the Holocene. Modern measurements, when reported together with archaeological data in original publications, are also included. The dataset consists of 5568 entries and covers the entirety of Africa, though most isotopic research has been concentrated in southern Africa. The AfriArch isotopic dataset can be used in paleodietary, paleodemography, paleoclimatic, and paleoenvironmental studies. It can also be employed to highlight data gaps across space …

Development Of Optical Coherence Tomography Angiography System For Mouse Eye Imaging And Measurement Of Vasodilation, Yilin Li

McKelvey School of Engineering Graduate Student Theses & Dissertations

Optical coherence tomography angiography (OCTA) is broadly known as a non-invasive technology that allows examining the retinal and choroidal vasculatures, alternative to fluorescein angiography. In this study, we have developed an optical coherence tomography (OCT) system for imaging the mouse eye. We measure the retinal thickness, which is 216.53um. We apply OCTA to characterize the quantitative change in vessel diameter and the perfusion density of the retina after the wild-type mice are administered the adenosine or inhale carbon dioxide. Comparing the images acquired one minute and 5 minutes after the injection or CO₂ inhalation with the baseline, distinct changes …

Comparing Hospital Costs & Lengths Of Stay For Cancer Patients In New York State Comprehensive Cancer Centers Vs. Non-Designated Academic Centers & Community Hospitals, Ryan Fodero

Economics Student Scholarship

This paper explores differences in costs and lengths of stay for cancer patients admitted to National Cancer Institute-designated Comprehensive Cancer Centers, non-designated academic medical centers, and community hospitals in New York State using patient-level data from the New York State Statewide Planning and Research Cooperative System Hospital Inpatient Discharges dataset from 2017-2019. We employ ordinary least squares and Poisson regressions to compare hospital costs and length of stay for cancer patients, controlling for hospital type, patient demographics, and patient health. Inpatient costs were 27% higher, but length of stay was 12% shorter, in comprehensive cancer centers relative to community hospitals. …

Adult Home Range Size And Juvenile Movements Of Gray Hawks In The Lower Rio Grande Valley, Texas, Usa, Michael T. Stewart, William S. Clark, Brian A. Millsap, Brent D. Bibles, Timothy Brush

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Biology)

We studied the natural history of Gray Hawks (Buteo plagiatus) in the Lower Rio Grande Valley of Texas. We used GPS-GSM telemetry to quantify dispersal time and distance, winter home range size of juveniles, and home range size of adults. Home ranges were calculated using the kernel Brownian bridge home range estimator. The median dispersal date for 14 juvenile Gray Hawks was 11 August and they traveled a median straight-line distance of 453 km. Mean winter home range sizes for 11 juveniles was 707 ha. For juveniles, female winter home ranges were larger than those of males, and …

Anticancer Effect Of Illicium Verum (Star Anise Fruit) Against Human Breast Cancer Mcf-7 Cell Line, Asra Khan Pahore, Shagufta Khan, Nasim Karim

Department of Biological & Biomedical Sciences

Objective: To investigate the anticancer effect of Illicium verum against human breast cancer MCF-7 cell line.
Methods: An experimental study was conducted in Multidisciplinary and Tissue Culture Laboratory, Aga Khan University in collaboration with Pharmacology Department of Bahria University Medical and Dental College, Karachi, Pakistan from January 2021 to June 2021. MCF-7 cells of Luminal-A breast cancer were seeded in 96-well plate and treated with I.verum methanol extract. After incubation, MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) dye was used for cell viability and cell proliferation assays to determine the number of dead and viable cells, and the absorbance was measured using an enzyme-linked …

Nuclear Energy, Evan Detina

Op-Eds from ENSC230 Energy and the Environment: Economics and Policies

The use of nuclear power as a primary energy source is a controversial discussion. However, if reversing or stopping the effects of climate change is our main goal, then this is a top contender. Fossil fuels account for 34 billion tons of emissions annually according to Ritchie, Hannah, et al. (2020). Instead, we can create energy through nuclear fission. I believe nuclear energy should become a much larger player in the energy game.

The first practical use of nuclear power became apparent on December 2, 1942 when a physicist, Enrico Fermi, develOp-ed a self-sustaining nuclear fission reaction at the University …

In Vitro Rooting Techniques In Prunus Spp. For Propagation And Disease Screening For Armillaria Root Rot (Arr) Resistance, John Lawson

All Theses

Prunus is a genus widely cultivated to produce edible fruit including almond (P. amygdalus), peach (P. persica (L.) Batsch), cherries (P. avium and P. cerasus), among others. The cultivation of Prunus is economically important for several regions of the United States and relies on appropriate cultivars and rootstocks that are adapted to a growing region. Encroaching plant pathogens are forcing breeders to use sexually compatible germplasm from related species for introgression of novel alleles that confer tolerance or resistance. This is especially true in the rootstock breeding where interspecific hybridization is often used …

Overview Of Triple Negative Breast Cancer Prognostic Signatures In The Context Of Data Science-Driven Clinico-Genomics Research., Enrico Capobianco

Faculty Research 2023

No abstract provided.

Analysis Of Genome-Wide Knockout Mouse Database Identifies Candidate Ciliopathy Genes., Kendall Higgins, Bret A Moore, Zorana Berberovic, Hibret A Adissu, Mohammad Eskandarian, Ann M Flenniken, Andy Shao, Denise M Imai, Dave Clary, Louise Lanoue, Susan Newbigging, Lauryl M J Nutter, David J Adams, Fatima Bosch, Robert Schneider, Steve D M Brown, Mary E Dickinson, Michael Dobbie, Paul Flicek, Xiang Gao, Sanjeev Galande, Anne Grobler, Jason D Heaney, Yann Herault, Martin Hrabe De Angelis, Hsian-Jean Genie Chin, Fabio Mammano, Chuan Qin, Toshihiko Shiroishi, Radislav Sedlacek, J-K Seong, Ying Xu, K C Kent Lloyd, Colin Mckerlie, Ala Moshiri

Faculty Research 2022

We searched a database of single-gene knockout (KO) mice produced by the International Mouse Phenotyping Consortium (IMPC) to identify candidate ciliopathy genes. We first screened for phenotypes in mouse lines with both ocular and renal or reproductive trait abnormalities. The STRING protein interaction tool was used to identify interactions between known cilia gene products and those encoded by the genes in individual knockout mouse strains in order to generate a list of "candidate ciliopathy genes." From this list, 32 genes encoded proteins predicted to interact with known ciliopathy proteins. Of these, 25 had no previously described roles in ciliary pathobiology. …

Implementing Oer At Laguardia Community College: Three Case Studies, Ian Mcdermott, Joshua P. Tan, Alioune Khoule, Marta Kowalczyk, Emma Handte, Rena D. Grossman

Publications and Research

LaGuardia Community College, City University of New York (CUNY) began receiving funds from a New York State Open Educational Resources (OER) grant in 2017. Since then, several departments have made significant strides in the implementation of OER. We offer three case studies of putting OER into practice, in math, astronomy, and chemistry. Each case study presents the context for OER conversion, the steps taken, early results from OER implementation, and the main takeaways. A common feature across courses and departments is a process-oriented implementation of OER, namely, one that is constantly improving and moving towards the goal of openness and …

Say It Ain’T Roe: Dobbs And Reason Bans Are Trojan Horses For The Down Syndrome Community, Calvin Lee

Minnesota Law Review Vols. 106:2 onward (2021-present)

In recent times, one of the most in vogue methods for curtailing abortion rights has been through the enactment of “reason bans,” statutes precluding abortions if the procedure is being sought due to the sex, race, or potential genetic abnormality of the fetus. This note_comment focuses on the contemporary litigation and discourse concerning reason bans’ genetic abnormality prong. In the immediate lead-up to the Supreme Court’s ruling in Dobbs, several reason ban statutes faced facial challenges in federal court, with the plaintiffs alleging that the statutes violated Casey’s undue burden standard by imposing categorical prohibitions on pre-viability abortions. Reason ban …

Efficacy Of A Typical Clean-In-Place Protocol Against In Vitro Membrane Biofilms, Diwakar Singh, Sanjeev Anand

Dairy Science and Food Science Faculty Publications: 2022 to Present

This study evaluates the effectiveness of a typical clean-in-place (CIP) protocol against in vitro biofilms on whey reverse osmosis (RO) membranes developed under static condition. Bacterial isolates obtained from RO membrane biofilms were used to develop single and multispecies biofilms under laboratory conditions. A typical commercial CIP protocol was tested against the 24-h-old biofilms, and included 6 sequential treatment steps based on alkali, surfactant, acid, enzyme, a second surfactant, and a sanitizer treatment step. Experiments were conducted in 4 replicates and the data were statistically analyzed. The results revealed a variation in the resistance of mixed-species biofilms against the individual …

Uterine Weight As A Modifier Of Black/White Racial Disparities In Minimally Invasive Hysterectomy Among Veterans With Fibroids In The Veterans Health Administration, Cathea M. Carey, Jodie G. Katon, Andrew S. Bossick, Kristen E. Gray, Kemi M. Doll, Alicia Y. Christy, Lisa S. Callegari

Public Health Sciences Articles

INTRODUCTION: Uterine fibroids are the most common indication for hysterectomy. Minimally invasive hysterectomy (MIH) confers lower risk of complications and shorter recovery than open surgical procedures; however, it is more challenging to perform with larger fibroids. There are racialized differences in fibroid size and MIH rates. We examined the role of uterine size in black-white differences in MIH among Veterans in the Department of Veterans Affairs (VA).

METHODS: Using VA clinical and administrative data, we conducted a cross-sectional study among black and white Veterans with fibroids who underwent hysterectomy between 2012 and 2014. We abstracted postoperative uterine weight from pathology …

U-Glide Program Fall 2022, Unf Office Of Undergraduate Research, Unf Graduate School

Undergraduate – Graduate Learning, Inquiry, and Distinctive Experimentation (U-GLIDE) Symposium Programs

No abstract provided.

Agent-Based Modeling Predicts Rac1 Is Critical For Ovarian Cancer Metastasis, Melanie Rivera, Leslie Toledo-Jacobo, Elsa Romero, Tudor I. Oprea, Melanie E. Moses, Laurie G. Hudson, Angela Wandinger-Ness, Martha M. Grimes

Pathology Research and Scholarship

Experimental and computational studies pinpoint rate-limiting step(s) in metastasis governed by Rac1. Using ovarian cancer cell and animal models, Rac1 expression was manipulated, and quantitative measurements of cell-cell and cell-substrate adhesion, cell invasion, mesothelial clearance, and peritoneal tumor growth discriminated the tumor behaviors most highly influenced by Rac1. The experimental data were used to parameterize an agent-based computational model simulating peritoneal niche colonization, intravasation, and hematogenous metastasis to distant organs. Increased ovarian cancer cell survival afforded by the more rapid adhesion and intravasation upon Rac1 overexpression is predicted to increase the numbers of and the rates at which tumor cells …

Assessing Knowledge And Perceptions About Cancer Among American Indians Of The Zuni Pueblo, Nm, Safia Safi, Donica Ghahate, Jeanette Bobelu, Andrew L. Sussman, Joseph Rodman, Angela Wandinger-Ness, Shiraz I. Mishra, Thomas Faber, Cheryl Willman, Vallabh Shah

Pathology Research and Scholarship

American Indians (AIs) in New Mexico have lower cancer screening rates compared to other populations and are more likely to be diagnosed with cancer at an advanced stage of the disease as reported by Li et al. (Archives of Internal Medicine 163(1):49-56, 2003). AIs also have the lowest 5-year cancer survival rates compared to any ethnic/racial group in the USA as reported by Clegg et al. (Arch Intern Med 162:1985-1993, 2002) and Edwards et al. (Cancer 97:1407-1427, 2005). Numerous barriers such as cultural beliefs, fear, fatalism, mistrust, stigma, and lack of culturally appropriate interventions could contribute to low cancer screening …

Microcosm Evaluation Of Natural And Biologically-Enhanced Abiotic Transformation Of Chlorinated Ethenes In Low Permeability Formations, Hao Wang

All Dissertations

Trichloroethene (TCE) is one of the most commonly found hazardous compounds at Superfund sites, especially in groundwater. Its volatility and toxicity pose a threat to drinking water safety and human health. In the past decades, research on the fate of TCE in the environment has shifted to contamination of low-permeability formations, for example fractured bedrock aquifers. TCE back-diffusion from low permeability zones and management of persistent TCE groundwater plumes caused by this long-term source zone pose major challenges for remediation.

Monitored natural attenuation (MNA) is a cost-effective remediation strategy that has gradually gained acceptance by regulators. Compared to extensive active …

The Role Of Vsmc Mir-33a Expression On Apoa-I Mediated Cholesterol Efflux And Macrophage-Like Cell Transdifferentiation, Ikechukwu Esobi

All Dissertations

Atherosclerosis is a condition caused by cholesterol accumulating in arterial intimal cells and is a disease that kills more people in the United States and globally than any other disease. Atherosclerosis is commonly recognized to arise from arterial intimal macrophage cholesterol accumulation, but cell lineage tracing technology has shown that a large majority of cholesterol-laden intimal cells found in atherosclerotic arteries are actually vascular smooth muscle cells that have switched phenotypes to a macrophage-like cell. This vascular smooth muscle cell to macrophage-like cell phenotypic switch is known as transdifferentiation and can be triggered by vascular smooth muscle cell cholesterol accumulation. …

Covid-19 Mitigation Strategies: A Natural Experiment Highlighting The Importance Of Structure In The Prevention And Treatment Of Childhood Obesity, Keith Brazendale, Michael Beets, Robert Weaver Med, Phd, Bridget Armstrong, Ethan T. Hunt

Faculty Publications

Societal restrictions due to the Coronavirus Disease 2019 (COVID-19), such as the closure of schools, childcare centers, and community programs, were implemented to prevent the spread of the disease and to protect the health and well-being of the population. These mitigation efforts drastically interrupted the day-to-day environments of children and adolescents and influenced how they spent the majority of their waking hours. Evidence shows on days when children and adolescents are in “structured” settings, such as school or other extracurricular programs or day camps, their obesogenic behaviors (i.e., sleep, physical activity, diet, and screen/media time) are more favorable than on …

2022-December-01-Etsu Scientist Captures State Award, University Marketing And Communication, East Tennessee State University

ETSU News

JOHNSON CITY – Dr. Lev Yampolsky, a respected scientist who has earned prestigious grants and published on a range of topics, has won the Tennessee Academy of Sciences 2022 Distinguished College/University Scientist Award.

It is among the highest honors available to scientists in the Volunteer State.  

Yampolsky is a professor in the Department of Biological Sciences at East Tennessee State University. 

“It is a great honor for me to receive the TAS Award. We have been lucky to publish a few good papers recently and this is probably what affected the choice of me among many, I am sure, highly …

2022-December-01-Etsu Rotc Will Commission Graduates, University Marketing And Communication, East Tennessee State University

ETSU News

JOHNSON CITY – Family, friends and programs supporters will gather as cadets in the Army ROTC Program at East Tennessee State University will be commissioned as second lieutenants.  

The 3 p.m. ceremony is in the Brown Hall Auditorium, located on the university’s main campus along Stout and Sherrod Drive near University School, on Friday, Dec. 9.  

Dr. Tom Kwasigroch, a professor in the Department of Medical Education and recipient of the Purple Heart for his service in Vietnam, will be the guest speaker. The winner of the Bronze Star and Army Commendation Medal, Kwasigroch taught at the Chemical Biological and …

2022-December-01-Joseph Headrick Wins Etsu's 3mt Competition, University Marketing And Communication, East Tennessee State University

ETSU News

JOHNSON CITY – Master’s degree student Joseph Headrick won East Tennessee State University’s recent 2022 3 Minute Thesis (3MT®) Competition with a presentation on “Salicylic Acid Inhibits Desiccation Survival of Salmonella Typhimurium.”

This competition, created at the University of Queensland, Australia, provides graduate students the opportunity to develop professional presentation and research communication skills. Participants condense complex research projects into engaging, three-minute presentations designed for a general audience using just one slide. Audience members learn what students in master’s and doctoral programs are studying and gain insight into the future of research, design and innovation in a variety of disciplines. …

Schramm Park Fall Field Days, Janis Paseka

Nebraska Bird Review

The 2022 NOU Fall Field Days were held at Schramm Park State Recreation Area, south of Gretna in Sarpy County, on September 21-23, with approximately 60 in attendance. The meeting had been scheduled and cancelled twice in the two previous years due to coronavirus concerns. The total species count was 119, including a Sandhill Crane, Prairie Falcon (early for away from breeding area), Winter Wren, and early Snow Bunting. A Limpkin, which had been found in late June at Wehrspann Wetlands mitigation pond in Sarpy County and was still seen through late November in the Wehrspann Lake area, was not …

The Nebraska Bird Review, Index To Volume 90

Nebraska Bird Review

From: Abbott, Sydney 56

To: Zonotrichia leucophrys oriantha 66, 146

The Nebraska Bird Review Volume 90 December 2022 Number 4

Nebraska Bird Review

Fall Field Report, August - November 2022 by W. Ross Silcock ...126

Remembering Clem Klaphake by Don Paseka ...151

Schramm Park Fall Field Days, Sept. 21-23, 2022 ... 154

Index to Volume 90 ...159

Subscription and Organization Information …175