Digital Commons Network^™

Systemic Risk Of Contract, Tal Kastner

Scholarly Works

Complexity and uncertainty define our world, now more than ever. Scholars and practitioners have celebrated modular contract design as an especially effective tool to manage these challenges. Modularity divides complex structures into relatively discrete, independent components with simple connections. The benefits of this fundamental drafting approach are intuitive. Lawyers divide contracts into sections and provisions to make them easier to understand and reduce uncertainty. Dealmakers constructing complex transactions use portable agreements as building blocks to reduce drafting costs and enable innovation. Little attention, however, has been paid to the risks introduced by modularity in contracts. This Article demonstrates how this …

Which Transportation Technologies Do We Want?, Michael Lewyn

Scholarly Works

A review of Todd Litman's book, New Mobilities- Smart Planning for Emerging Transportation Technologies

Global Climate Governance In 3d: Mainstreaming Geoengineering Within A Unified Framework, Gabriel Weil

Scholarly Works

The failure of conventional climate change mitigation to reduce climate-related risks to tolerable levels has spurred interest in more unconventional—and riskier—climate interventions. What currently sounds like science fiction could become a reality in the not-so-distant future: planes blasting particles into the sky to block the sun, vast deserts covered with mirrors, algae sucking carbon into the depths of the ocean. Scholars tend to lump all these unconventional climate measures together in a fuzzy category called “geoengineering,” and set them apart from conventional climate change mitigation. But the characteristics of climate interferences vary across three distinct dimensions, which the mitigation-geoengineering dichotomy …

Intentional Discrimination And Haredi Jews, Michael Lewyn

Scholarly Works

No abstract provided.

Why Arkansas Act 710 Was Upheld, And Will Be Again, Mark Goldfeder

Scholarly Works

The recent Eighth Circuit ruling in Arkansas Times, LP v. Waldrip, a lawsuit revolving around an Arkansas state anti-discrimination bill, has been widely misreported and generally misunderstood. While the decision was actually very narrow, case-specific, and ripe for review, the misleading information presented to the public has led to speculation and fear that similar anti-discrimination legislation in dozens of other states might somehow be constitutionally deficient. This essay will clarify what actually happened in the Arkansas case, and explain why legislators and advocates around the country do not have to worry about this very limited opinion affecting the legality of …

Fertility Care: Essential Or Non-Essential? Lessons From The Covid-19 Pandemic, Rebecca S. Feinberg

Scholarly Works

At the beginning of the COVID-19 pandemic, in an effort to allocate medical resources towards the anticipated influx of patients infected with the novel virus, many non-essential healthcare services were temporarily paused. The American Society of Reproductive Medicine led the move to halt infertility care in all but the most extreme cases. This cessation of infertility care, compounded by the unknown duration of this recommendation, added to the already high level of stress and anxiety that fertility patients experience and in cases of advanced maternal age or diminished ovarian reserve potentially resulted in suboptimal clinical outcomes. There was vocal disagreement …

Investigation Of The Users’ Access To Health Information For Sustainable Development During The Covid 19 Era In Professor Kenneth Dike E-Central Library, Awka, Anambra State, Eliezer C. Agim, Maureen Azolo

Library Philosophy and Practice (e-journal)

The research investigated users’ access to health information for sustainable development during the Covid 19 era in Professor Kenneth Dike E-central Library, Awka, Anambra state. A descriptive survey research design was used for the study. The sample population comprised of 100 users of Professor Kenneth Dike E-central Library through the use of accidental sampling technique. A structured questionnaire was used for collection of data. The instrument was subjected to face validation and pilot test using Cronbach Alpha which gave a reliability coefficient value of 0.97. Data collected from the study were analyzed using mean scores. The study found that health …

Rejuvenating Academic Libraries For Effective Service Delivery In The Post Covid-19 Era, Emuejevoke Paul Ogo Mr, Angela Chiwendu Nweke Mrs, Ademola Ferdinand Omosekejimi Mr

Library Philosophy and Practice (e-journal)

This study focused on rejuvenating academic libraries for effective service delivery in the post COVID 19 era. The offering of online services in academic libraries has received attention as a result of the COVID-19 epidemic, with higher educational institutions all across the world adopting this development as the "new normal." The pandemic has posed several difficulties for most universities and its academic libraries, particularly for those with weaker online presence. It however sparked transformation and a re-evaluation of priorities; providing a new purpose for academic libraries that provide information services 24 hours a day. This mission focuses on access and …

Fourth Industrial Revolution (4ir) Technologies As Catalyst For Partnership And Collaboration Among Libraries In Nigeria: A Review, Amugen Sarah Akpobasah Mrs, Gloria Ngozi Mordi Mrs (Cln), Ochigbihi Prince Owoicho Mr, Ademola Ferdinand Omosekejimi Mr (Cln)

Library Philosophy and Practice (e-journal)

This study is a review of fourth industrial revolution (4IR) technologies as catalyst for partnership and collaboration among libraries in Nigeria. The study reviewed relevant literature on issues bothering on concept of partnership and collaboration, concept of fourth industrial revolution (4IR), technologies associated with 4IR, 4IR technologies that can be used for partnership and collaboration in libraries, cloud computing applications that are useful for partnership and collaboration in libraries, importance of 4IR technologies to partnership and collaboration in libraries and challenges of using cloud computing technologies for partnership and collaboration in libraries. The study reviewed relevant literature on the topic …

Contributions To The Field Of Library And Information Sciences In Pakistan: A Bio Bibliometric Study Of Dr. Saeed Ullah Jan, Abid Hussain Mr, Nasir Shakoor

Library Philosophy and Practice (e-journal)

Abstract

Purpose- This paper presents the bio-bibliometric analysis of Dr. Saeed Ullah Jan's contributions to the Library and Information Science (LIS) field in Pakistan. This study includes the following: the year-wise distribution of research produced; authors' collaboration; publications by type; language; geographical preference for research; and coverage of different subject areas.

Methodology/Design- The data for this retrospective study was requested through email from Dr. Saeed Ullah Jan with advance ethical permission and further verified from Scholar Google, the official university website, and departments where required.

Findings- The results of the study indicate that Dr. Saeed Ullah Jan is a prolific …

Documentation Of Nigerian Indigenous Knowledge System: The Role Of The Library, Christopher Agbeniaru Omigie Dr., Theresa Osasu Makinde Mrs., Ademola Victor Adeniran Mr.

Library Philosophy and Practice (e-journal)

This paper is on documentation of Nigerian indigenous knowledge system (IKS) as a national heritage through the role of the library as catalyst. The paper used literature analysis, recognizance survey and observations to explicitly describe the concept of IKS and its various sustainable ethos; it illustrates the components of the Nigerian IKS including the encompassed spiritual and physical sustainable elements that helps to promote its long time survival. Also treated in the paper are the relevance of IKS to the Nigerian national development; the challenges of IKS development in the country and the role of the library for sustainable collection …

Evaluating The Use Of Electronic Resources At Selected Iims In India, Sanjeev Kumar Jha Mr., Praveen Babel Dr.

Library Philosophy and Practice (e-journal)

Efficient use of resources is critical for development. Electronic resources and Web-based library services (WBLS) in the era of modernization and technological advancement marks a prominent role. Given such importance to these electronic resources and web-based library services, to understand their efficient use and user’s patterns as well as the purpose of utilization, this paper tries to assess the usability, and perception regarding web-based library services and electronic resources. For this purpose, the paper utilizes the primary field data from 300 students of selected IIMs in India. In the course of imparting quality management education by selected institutions, the libraries …

Analysis Of Digital Information Management Strategies By The Faculties Of Higher Education Institutions, Ashoka R., Pavan N.S., Priya R.

Library Philosophy and Practice (e-journal)

The present study investigated ‘Digital Information Management practices pertaining to personal and professional digital information by the faculties of ‘Higher Education Institutions’. The study is envisioned to discover the use of Digital Information Management (DIM) and all its multiplicity, degree of usage, form and formats, advantages, and problems encountered while practicing digital preservation and access. This qualitative study used the survey method and questionnaire technique for data accumulation. The study reveals that almost 50% of the faculty members manage their digital content and perceive that they acquired their skills towards DIM from themselves and their colleagues and friends. As the …

Use Of Mobile Social Media For Academic Activities By Undergraduate Students At The Federal University Of Lafia, Nigeria, Alice Olije Odu, Madely Du Preez

Library Philosophy and Practice (e-journal)

In this article, we report on a phenomenological study that explored the use of mobile social media by 21 undergraduate students registered at the Federal University of Lafia, Nigeria, to support their academic-related information needs and activities. Furthermore, in the study, we attempted to acquire an understanding of why these students seem to prefer using their mobile devices and the ways in which their use of mobile devices affect their academic-related information seeking. Following an explanation of what social media entails, the discussion focused on the ways in which information-behaviour elements such as context, the user’s inner person and information …

The Creation Of Primary Sources Digital Collections In An Academic Library, Keren Barner

Library Philosophy and Practice (e-journal)

This article discusses the creation of primary sources digital collections in an academic library, including implementation, work processes, digitization and providing accessibility of visual materials. These reflect the practical application of the approach developed in The Younes and Soraya Nazarian Library at the University of Haifa regarding the library's position in the field of digital collections. The article denotes the work process model created for these collections, from their reception, through classification, cataloging, scanning and digitization, and to the digital publishing which provides access. Special emphasis is given to practical ways to manage the challenges that arise from handing unique …

An Assessment Of Students’ Records Management System And Preservation As A Determinant For The Effective Retrieval And Dissemination Of Information In Tertiary Institutions In Kogi State, Nigeria., Emmanuel Adeniyi Oloniruha, Khalimat Oyiza Momohjimoh

Library Philosophy and Practice (e-journal)

The main purpose of this study is to assess students’ records management system and preservation as a determinant for the effective retrieval and dissemination of information in tertiary institutions in the state under study. The objective of the study is to determine how students’ records are organised, preserved, managed, retrieved, and the challenges encountered. The study sample population comprised of 92selected records management personnel from some randomly selected tertiary institutions in Kogi State, Nigeria. Descriptive survey method using simple random sampling techniques is used for the study; observation and questionnaire are the instrument used for data collection. The major …

Use Of Internet Of Things (Iot) Technologies In Indian Institutes Of Management (I.I.M.) Libraries: A Study, Manoj Kumar Pant Mr., Udita Negi, Surabhi Seth Ms

Library Philosophy and Practice (e-journal)

Libraries as social institutions have always kept pace with the technological advancements in society to stay relevant. In recent years, the Internet of Things (IoT) is one such area that has opened enormous opportunities in almost all areas which have the intrusion of computers and the internet. IoT has not only helped Libraries to add value to traditional services but has also helped in collecting valuable data to supplement decision-making. This study examined the extent of use of the Indian Institute of Management (I.I.M.) Libraries are one of the premium brands of professional education in India. The study observed that …

Seeking Clarity In Murky Waters: Nuances Of Equity And Social Justice From A Teacher Perspective, Elaine J. Chan

Department of Teaching, Learning, and Teacher Education: Faculty Publications

In this study, I examined interactions between an English teacher and her students to illustrate ways in which issues of equity and social justice may play out in nuanced ways in the implementation of school curriculum in a diverse, Midwestern high school. These stories of classroom teacher and student experiences reveal complexities of how equity and social justice might unfold for students, and be understood by a teacher as she works with her students, to build a body of “teacher knowledge” (Clandinin and Connelly, 1996) that grows as the teacher gains experience. Examining complexities of “teacher knowledge” as a classroom …

Considering The Needs, Challenges, And Assets Of School Systems In Rural Meatpacking Communities During Covid-19: The Roles Of Schools As Vehicles Of Community, Edmund T. Hamann, Amanda R. Morales, Ricardo Martinez

Department of Teaching, Learning, and Teacher Education: Faculty Publications

For more than 40 years, the relocation of meatpacking from urban to rural communities and the related change of who works in these high-risk, modestly compensated positions has brought Spanish-speaking and African and Asian refugee populations to communities like the seven focal Nebraska communities we consider here. These seven, five rural and two part of multi-county metropolitan areas, all have majority Latinx school enrollments and they all have been particularly hard hit by both the first and third waves of the COVID-19 pandemic. They were each also foci of a special new course we co-taught in December 2020 called: “Pandemics, …

Phase I Clinical Trial Evaluating The Safety And Efficacy Of Adp-A2m10 Spear T Cells In Patients With Mage-A10+ Advanced Non-Small Cell Lung Cancer, George R Blumenschein, Siddhartha Devarakonda, Ramaswamy Govindan, Et Al

2020-Current year OA Pubs

BACKGROUND: ADP-A2M10 specific peptide enhanced affinity receptor (SPEAR) T cells (ADP-A2M10) are genetically engineered autologous T cells that express a high-affinity melanoma-associated antigen A10 (MAGE-A10)-specific T-cell receptor (TCR) targeting MAGE-A10

METHODS: Eligible patients were HLA-A*02 positive with advanced NSCLC expressing MAGE-A10. Patients underwent apheresis; T cells were isolated, transduced with a lentiviral vector containing the TCR targeting MAGE-A10, and expanded. Patients underwent lymphodepletion with varying doses/schedules of fludarabine and cyclophosphamide prior to receiving ADP-A2M10. ADP-A2M10 were administered at 0.08-0.12×10

RESULTS: Eleven patients (male, n=6; female, n=5) with NSCLC (adenocarcinoma, n=8; squamous cell carcinoma, n=3) were treated. Five, three, and three …

Checkpoint Blockade-Induced Cd8+ T Cell Differentiation In Head And Neck Cancer Responders, Liye Zhou, Paul Zolkind, Obi Griffith, Et Al

2020-Current year OA Pubs

BACKGROUND: Immune checkpoint blockade (ICB) response in recurrent/metastatic head and neck squamous cell carcinoma (HNSCC) is limited to 15%-20% of patients and underpinnings of resistance remain undefined.

METHODS: Starting with an anti-PD1 sensitive murine HNSCC cell line, we generated an isogenic anti-PD1 resistant model. Mass cytometry was used to delineate tumor microenvironments of both sensitive parental murine oral carcinoma (MOC1) and resistant MOC1esc1 tumors. To examine heterogeneity and clonal dynamics of tumor infiltrating lymphocytes (TILs), we applied paired single-cell RNA and TCR sequencing in three HNSCC models.

RESULTS: Anti-PD1 resistant MOC1esc1 line displayed a conserved cell intrinsic immune evasion signature. …

Episodic Memories Among Irritable Bowel Syndrome (Ibs) Patients: An Important Aspect Of The Ibs Symptom Experience, Gregory S Sayuk, Carol S North, David E Pollio, Britt M Gott, David H Alpers

2020-Current year OA Pubs

Objective: Some IBS patients possess detailed memories of the events surrounding their bowel symptom onset ("episodic memories"). In this exploratory study we sought to: (1) examine memory relationship with gastrointestinal (GI) symptom severity, extraintestinal symptoms, and mood; (2) qualitatively explore memory valence and content in IBS patients with or without episodic memories.

Methods: Referral IBS patients

Results: 14/29 (48.3%) of IBS subjects endorsed episodic memories of IBS symptom onset, often GI infections/enteritis (35.7%). Recall of the exact year (69%) and month (60%) of symptom onset were common. Episodic memories were associated with greater IBS symptom severity/bother, higher anxiety/depression, and poorer …

Case Report: A Novel Eif2b3 Pathogenic Variant In Central Nervous System Hypomyelination/Vanishing White Matter, Parith Wongkittichote, Soe Soe Mar, Robert C Mckinstry, Hoanh Nguyen

2020-Current year OA Pubs

Leukodystrophies are a group of heterogeneous disorders affecting brain myelin. Among those, childhood ataxia with central nervous system hypomyelination/vanishing white matter (CACH/VWM) is one of the more common inherited leukodystrophies. Pathogenic variants in one of the genes encoding five subunits of EIF2B are associated with CACH/VWM. Herein, we presented a case of CACH/VWM who developed ataxia following a minor head injury. Brain magnetic resonance imaging showed extensive white matter signal abnormality. Diagnosis of CACH/VWM was confirmed by the presence of compound heterozygous variants in

Maternal Perceptions About Sensory Interventions In The Neonatal Intensive Care Unit: An Exploratory Qualitative Study, Julia Lisle, Kylie Buma, Joan Smith, Marinthea Richter, Prutha Satpute, Roberta Pineda

2020-Current year OA Pubs

Background: Mothers play an important role in providing positive sensory experiences to their infants during NICU hospitalization. However, little is known regarding maternal perceptions about sensory-based interventions in the NICU. Further, understanding maternal perceptions was an important part of the process during development of the Supporting and Enhancing NICU Sensory Experiences (SENSE) program.

Methods: Twenty mothers of very preterm infants were interviewed after NICU discharge and asked open-ended questions about sensory-based interventions they performed in the NICU and probed about their perceptions related to the development of a sensory-based guideline and the use of volunteers to provide sensory-based interventions when …

Predictors Of Lung Adenocarcinoma With Leptomeningeal Metastases: A 2022 Targeted-Therapy-Assisted Molgpa Model, Milan Zhang, Jiayi Tong, Weifeng Ma, Chongliang Luo, Huiqin Liu, Yushu Jiang, Lingzhi Qin, Xiaojuan Wang, Lipin Yuan, Jiewen Zhang, Fuhua Peng, Yong Chen, Wei Li, Ying Jiang

2020-Current year OA Pubs

Objective: To explore prognostic indicators of lung adenocarcinoma with leptomeningeal metastases (LM) and provide an updated graded prognostic assessment model integrated with molecular alterations (molGPA).

Methods: A cohort of 162 patients was enrolled from 202 patients with lung adenocarcinoma and LM. By randomly splitting data into the training (80%) and validation (20%) sets, the Cox regression and random survival forest methods were used on the training set to identify statistically significant variables and construct a prognostic model. The C-index of the model was calculated and compared with that of previous molGPA models.

Results: The Cox regression and random forest models …

Associations Of Polymorphisms In The Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Gene With Subsequent Coronary Heart Disease: An Individual-Level Meta-Analysis, Tessa Schillemans, Sharon Cresci, Et Al

2020-Current year OA Pubs

No abstract provided.

A Callosal Biomarker Of Behavioral Intervention Outcomes For Autism Spectrum Disorder? A Case-Control Feasibility Study With Diffusion Tensor Imaging, Javier Virues-Ortega, Nicole S. Mckay, Jessica C. Mccormack, Nerea Lopez, Rosalie Liu, Ian Kirk

2020-Current year OA Pubs

Tentative results from feasibility analyses are critical for planning future randomized control trials (RCTs) in the emerging field of neural biomarkers of behavioral interventions. The current feasibility study used MRI-derived diffusion imaging data to investigate whether it would be possible to identify neural biomarkers of a behavioral intervention among people diagnosed with autism spectrum disorder (ASD). The corpus callosum has been linked to cognitive processing and callosal abnormalities have been previously found in people diagnosed with ASD. We used a case-control design to evaluate the association between the type of intervention people diagnosed with ASD had previously received and their …

Where Do T Cell Subsets Stand In Sars-Cov-2 Infection: An Update, Mohammad Tarique, Mohd Suhail, Huma Naz, Naoshad Muhammad, Shams Tabrez, Torki A Zughaibi, Adel M Abuzenadah, Anwar M Hashem, Hari Shankar, Chaman Saini, Alpana Sharma

2020-Current year OA Pubs

An outbreak of coronavirus disease 2019 (COVID-19) emerged in China in December 2019 and spread so rapidly all around the globe. It's continued and spreading more dangerously in India and Brazil with higher mortality rate. Understanding of the pathophysiology of COVID-19 depends on unraveling of interactional mechanism of SARS-CoV-2 and human immune response. The immune response is a complex process, which can be better understood by understanding the immunological response and pathological mechanisms of COVID-19, which will provide new treatments, increase treatment efficacy, and decrease mortality associated with the disease. In this review we present a amalgamate viewpoint based on …

Advances In Understanding Interferon-Mediated Immune Responses To Enteric Viruses In Intestinal Organoids, Lila S Nolan, Megan T Baldridge

2020-Current year OA Pubs

Interferons (IFN) are antiviral cytokines with critical roles in regulating pathogens at epithelial barriers, but their capacity to restrict human enteric viruses has been incompletely characterized in part due to challenges in cultivating some viruses

Is Characteristic Frequency Limiting Real-Time Electrocochleography During Cochlear Implantation?, Amit Walia, Matthew A Shew, Shannon M Lefler, Dorina Kallogjeri, Cameron C Wick, Timothy A Holden, Nedim Durakovic, Amanda J Ortmann, Jacques A Herzog, Craig A Buchman

2020-Current year OA Pubs

Objectives: Electrocochleography (ECochG) recordings during cochlear implantation have shown promise in estimating the impact on residual hearing. The purpose of the study was (1) to determine whether a 250-Hz stimulus is superior to 500-Hz in detecting residual hearing decrement and if so; (2) to evaluate whether crossing the 500-Hz tonotopic, characteristic frequency (CF) place partly explains the problems experienced using 500-Hz.

Design: Multifrequency ECochG comprising an alternating, interleaved acoustic complex of 250- and 500-Hz stimuli was used to elicit cochlear microphonics (CMs) during insertion. The largest ECochG drops (≥30% reduction in CM) were identified. After insertion, ECochG responses were measured …