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2022

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Behavioral Strategies Of Prehistoric And Historic Children From Dental Microwear Texture Analysis, Almudena Estalrrich, Kristin L. Krueger Dec 2022

Behavioral Strategies Of Prehistoric And Historic Children From Dental Microwear Texture Analysis, Almudena Estalrrich, Kristin L. Krueger

Anthropology: Faculty Publications and Other Works

Reconstructing the dietary and behavioral strategies of our hominin ancestors is crucial to understanding their evolution, adaptation, and overall way of life. Teeth in general, and dental microwear specifically, provide a means to examine these strategies, with posterior teeth well positioned to tell us about diet, and anterior teeth helping us examine non-dietary tooth-use behaviors. Past research predominantly focused on strategies of adult individuals, leaving us to wonder the role children may have played in the community at large. Here we begin to address this by analyzing prehistoric and historic children through dental microwear texture analysis of deciduous anterior teeth.


Fixing The Taxation System - Part I, Ishrat Husain Dr. Dec 2022

Fixing The Taxation System - Part I, Ishrat Husain Dr.

Faculty Research - Newspaper and Magazine Articles

Very few people outside the economics profession realize that fiscal (government revenue and expenditure) and current accounts (inflows and outflows of foreign exchange) are closely interlinked. A current account is an accounting identity which shows the difference between a country’s national savings and domestic investments. China is a current account surplus country because its national savings are higher than its investment needs and is therefore a capital exporting nation that is financing the current account deficit of the US. Pakistan, except for three years – 2003, 2004 and 2005 – has been a current account deficit country. Since significant foreign …


Machine Learning Of Plasma Metabolome Identifies Biomarker Panels For Metabolic Syndrome: Findings From The China Suboptimal Health Cohort, Hao Wang, Youxin Wang, Xingang Li, Xuan Deng, Yuanyuan Kong, Wei Wang, Yong Zhou Dec 2022

Machine Learning Of Plasma Metabolome Identifies Biomarker Panels For Metabolic Syndrome: Findings From The China Suboptimal Health Cohort, Hao Wang, Youxin Wang, Xingang Li, Xuan Deng, Yuanyuan Kong, Wei Wang, Yong Zhou

Research outputs 2022 to 2026

Background: Metabolic syndrome (MetS) has been proposed as a clinically identifiable high-risk state for the prediction and prevention of cardiovascular diseases and type 2 diabetes mellitus. As a promising “omics” technology, metabolomics provides an innovative strategy to gain a deeper understanding of the pathophysiology of MetS. The study aimed to systematically investigate the metabolic alterations in MetS and identify biomarker panels for the identification of MetS using machine learning methods. Methods: Nuclear magnetic resonance-based untargeted metabolomics analysis was performed on 1011 plasma samples (205 MetS patients and 806 healthy controls). Univariate and multivariate analyses were applied to identify metabolic biomarkers …


End Crime With Harm? Castration For Sexual Offenders In Hong Kong, Max Hua Chen Dec 2022

End Crime With Harm? Castration For Sexual Offenders In Hong Kong, Max Hua Chen

San Diego International Law Journal

The issue of post-conviction treatment of sex offenders has been the subject of debate and changes to State legislation, particularly in respect of paedophile offences. One such treatment method is through chemical or physical castration on either a mandatory or a voluntary basis. In this regard, some States have implemented these measures for certain paedophile offences. Hong Kong (HK) has no such laws in place. Researchers such as William Winslade and his colleagues highlighted that whilst paedophilia may not be a stringently defined condition, it is one which involves a “reinforcing [pattern] of sexual behaviors,” with the result that sexual …


‘I Will Control Your Mind’: The International Regulation Of Brain-Hacking, Thibault Moulin Dec 2022

‘I Will Control Your Mind’: The International Regulation Of Brain-Hacking, Thibault Moulin

San Diego International Law Journal

In the near future, the use of neurotechnologies—like brain-computer interfaces and brain stimulation—could become widespread. It will not only be used to help persons with disabilities or illness, but also by members of the armed forces and in everyday life (e.g., for entertainment and gaming). However, recent studies suggested that it is possible to hack into neural devices to obtain information, inflict pain, induce mood change, or influence movements. This Article anticipates three scenarios which may be challenging in the future—i.e., brain hacking for the purpose of reading thoughts, remotely controlling someone, and inflicting pain or death—and assesses their compliance …


Deportations For Drug Convictions In The United States And The European Union: Creating A More Compassionate Approach Toward Drug Convictions In The Immigration Law, Megan Smith Dec 2022

Deportations For Drug Convictions In The United States And The European Union: Creating A More Compassionate Approach Toward Drug Convictions In The Immigration Law, Megan Smith

San Diego International Law Journal

This Comment begins by examining and comparing the legal framework for deportation and other immigration consequences for convictions of drug offenses in the United States, the European Union, and the United Kingdom. This Comment then looks at the harsh effects of current immigration policy on individuals and marginalized communities. Finally, this Comment argues that immigration law should be reformed to adopt a more humanitarian approach toward non-citizens convicted of drug offenses. Deportation and other harsh immigration consequences for drug offenses levy disproportionately severe punishments toward vulnerable minority immigrant communities, exposing them to consequences much harsher than non-immigrants would face for …


K-Pop’S Secret Weapon: South Korea’S Criminal Defamation Laws, Rebecca Xu Dec 2022

K-Pop’S Secret Weapon: South Korea’S Criminal Defamation Laws, Rebecca Xu

San Diego International Law Journal

South Korea’s criminal defamation laws have long been considered an intrusion on the free speech rights of citizens, especially in regard to the usage by politicians against their opponents and journalists to suppress criticisms. This Comment considers the history and effects of these controversial defamation laws through the lens of recent scandals within the Korean entertainment industry, where regular citizens accusing Korean celebrities of past school violence are confronted with threats of defamation charges. To highlight the controversial nature of such laws, comparisons will be drawn between South Korea and other countries to highlight the restrictive nature of Korea’s laws.


Highly Efficient Photocatalysts For Methylene Blue Degradation Based On A Platform Of Deposited Go-Zno Nanoparticles On Polyurethane Foam, Mohamed Morsy Dec 2022

Highly Efficient Photocatalysts For Methylene Blue Degradation Based On A Platform Of Deposited Go-Zno Nanoparticles On Polyurethane Foam, Mohamed Morsy

Nanotechnology Research Centre

No abstract provided.


Feeling The Heat: Climate Change Is Becoming A Big Factor In Business Decision-Making, Risk Assessment, Candace Beeke, Sahan Dissanayake, Jennifer Price, Moss Adams Dec 2022

Feeling The Heat: Climate Change Is Becoming A Big Factor In Business Decision-Making, Risk Assessment, Candace Beeke, Sahan Dissanayake, Jennifer Price, Moss Adams

Economics Faculty Publications and Presentations

Portland Business Journal Publisher and President Candace Beeke spoke recently with PSU’s Sahan Dissanayake and Jennifer Price, with Moss Adams, about the direct and indirect effects of climate change on business, along with the physical impacts and economic hazards. Here are their insights.


Proximity-Dependent Biotin Labeling In Testicular Germ Cells Identified Tesmin-Associated Proteins, Seiya Oura, Akinori Ninomiya, Fuminori Sugihara, Martin M Matzuk, Masahito Ikawa Dec 2022

Proximity-Dependent Biotin Labeling In Testicular Germ Cells Identified Tesmin-Associated Proteins, Seiya Oura, Akinori Ninomiya, Fuminori Sugihara, Martin M Matzuk, Masahito Ikawa

Faculty, Staff and Students Publications

Characterization of protein-protein interactions (PPI) is a key to understanding the functions of proteins of interest. Recently developed proximity-dependent biotin identification (BioID) has been actively investigated as an alternative PPI mapping method because of its usefulness in uncovering transient PPI. Here, as an example of proximity labeling proteomics application in the testis, we generated two transgenic mouse lines expressing two biotin ligases (BioID2 or TurboID) fused with TESMIN, which translocates from the cytosol to the nucleus during meiotic progression and is required for reproduction. The BioID2 transgene, albeit not the TurboID transgene, rescued fertility defects of the Tesmin KO male …


In Silico Activity And Admet Profiling Of Phytochemicals From Ethiopian Indigenous Aloes Using Pharmacophore Models, Lemessa Etana Bultum, Gemechu Bekele Tolossa, Gwangmin Kim, Ohhyeon Kwon, Doheon Lee Dec 2022

In Silico Activity And Admet Profiling Of Phytochemicals From Ethiopian Indigenous Aloes Using Pharmacophore Models, Lemessa Etana Bultum, Gemechu Bekele Tolossa, Gwangmin Kim, Ohhyeon Kwon, Doheon Lee

2020-Current year OA Pubs

In silico profiling is used in identification of active compounds and guide rational use of traditional medicines. Previous studies on Ethiopian indigenous aloes focused on documentation of phytochemical compositions and traditional uses. In this study, ADMET and drug-likeness properties of phytochemicals from Ethiopian indigenous aloes were evaluated, and pharmacophore-based profiling was done using Discovery Studio to predict therapeutic targets. The targets were examined using KEGG pathway, gene ontology and network analysis. Using random-walk with restart algorithm, network propagation was performed in CODA network to find diseases associated with the targets. As a result, 82 human targets were predicted and found …


Mrs Alma Rita Youmans Dec 2022

Mrs Alma Rita Youmans

African American Funeral Programs

Mrs_Alma_Rita_Youmans,pdf - Funeral program for Mrs. Alma Rita Youmans


Trem2 Dependent And Independent Functions Of Microglia In Alzheimer's Disease, Jinchao Hou, Yun Chen, Gary Grajales-Reyes, Marco Colonna Dec 2022

Trem2 Dependent And Independent Functions Of Microglia In Alzheimer's Disease, Jinchao Hou, Yun Chen, Gary Grajales-Reyes, Marco Colonna

2020-Current year OA Pubs

Microglia are central players in brain innate immunity and have been the subject of extensive research in Alzheimer's disease (AD). In this review, we aim to summarize the genetic and functional discoveries that have advanced our understanding of microglia reactivity to AD pathology. Given the heightened AD risk posed by rare variants of the microglial triggering receptor expressed on myeloid cells 2 (TREM2), we will focus on the studies addressing the impact of this receptor on microglia responses to amyloid plaques, tauopathy and demyelination pathologies in mouse and human. Finally, we will discuss the implications of recent discoveries on microglia …


Information Seeking Behaviour Of Newspaper Journalists Of Karnataka State: A Study, Rajashekhar Mahadevagouda, Pavithrabai M S Dec 2022

Information Seeking Behaviour Of Newspaper Journalists Of Karnataka State: A Study, Rajashekhar Mahadevagouda, Pavithrabai M S

Library Philosophy and Practice (e-journal)

Journalists search, access, and make use of a variety of information sources, both in print and electronic media. Journalists have been increasingly reliant on internet tools in recent years. An attempt has been made through the study to identify the information-seeking behaviour of journalist working in 39 newspapers at the national, state, as well as regional levels. A total of 610 respondents have responded to the questionnaire. The data shows that data indicates that approximately 60% of the respondents are below 35 years. The study witnessed that more than 30% of respondents opined that the information required about all areas …


Lecturers’ Awareness, Perception And Utilization Of Institutional Repositories In Two Universities In Nigeria, Lawrence Akingbade Dec 2022

Lecturers’ Awareness, Perception And Utilization Of Institutional Repositories In Two Universities In Nigeria, Lawrence Akingbade

Library Philosophy and Practice (e-journal)

Abstract

The purpose of this study was to examine the lecturers awareness, perception and utilisation of institutional repositories in two universities in Nigeria. The universities include the Ahmadu Bello University, Zaria and University of Jos. The research design adopted for the study was correlational research design, while the questionnaire was the instrument used for data collection. The questionnaire was grouped into five sections and most of the questions were close ended. Also validity and reliability of the questionnaire was done in order to obtain the desired results. Out of 642 number of questionnaire distributed, 473 were completed, returned and found …


Information Retrieval Skills As Correlate Of Scholarly Research Among Postgraduate Students In Selected Universities In Oyo And Lagos States, Nigeria, Kolawole Oluwatola, Lawrence Akingbade Dec 2022

Information Retrieval Skills As Correlate Of Scholarly Research Among Postgraduate Students In Selected Universities In Oyo And Lagos States, Nigeria, Kolawole Oluwatola, Lawrence Akingbade

Library Philosophy and Practice (e-journal)

Abstract

The main objective of the study is to investigate information retrieval skills as correlate of scholarly research among postgraduate students in selected Universities in Oyo and Lagos States, Nigeria. Survey research methodology was used with a total sample size of 379 using single random sampling techniques to select postgraduate students. Data was collected mainly through questionnaire and analyzed using frequency distribution and regression analysis run on SPSS (2.0). The result revealed the types of information retrieval skills, the study revealed that information retrieval skills highly influence the postgraduate students’ scholarly research as it allowed them to easily recognition their …


Associations Between Mental Health And Hiv Status Among Sexual Minority And Heterosexual Adolescents In Nigeria, Morenike Oluwatoyin Folayan, Olakunle Oginni, Olanrewaju Ibikunle Ibigbami, Uma Philip, Nserd Ntonoba Mfam, Chinedu Mbam, Amos Ganyam, Agada A Salem, Christopher Osuji, Cory Bradley, Joanne Lusher, Nadia Adjoa Sam-Agudu Dec 2022

Associations Between Mental Health And Hiv Status Among Sexual Minority And Heterosexual Adolescents In Nigeria, Morenike Oluwatoyin Folayan, Olakunle Oginni, Olanrewaju Ibikunle Ibigbami, Uma Philip, Nserd Ntonoba Mfam, Chinedu Mbam, Amos Ganyam, Agada A Salem, Christopher Osuji, Cory Bradley, Joanne Lusher, Nadia Adjoa Sam-Agudu

2020-Current year OA Pubs

BACKGROUND: We aimed to determine associations between the mental health status of adolescents by self-reported sexual identity; and to determine associations between the mental health status of sexual minority adolescents living with and without HIV.

METHODS: This cross-sectional study collected data from Nigerians aged 13-19 years old using an online survey. We collected information on dependent (sexual identity) and independent (presence of depressive symptoms, generalised anxiety disorder, suicidal attempt/ideation, HIV status) study variables. A multivariate regression model determined associations between the dependent and independent variables. A second multivariate regression model was developed to establish associations between HIV status among sexual …


The Role Of Er Stress In Diabetes: Exploring Pathological Mechanisms Using Wolfram Syndrome, Shuntaro Morikawa, Fumihiko Urano Dec 2022

The Role Of Er Stress In Diabetes: Exploring Pathological Mechanisms Using Wolfram Syndrome, Shuntaro Morikawa, Fumihiko Urano

2020-Current year OA Pubs

The endoplasmic reticulum (ER) is a cytosolic organelle that plays an essential role in the folding and processing of new secretory proteins, including insulin. The pathogenesis of diabetes, a group of metabolic disorders caused by dysfunctional insulin secretion (Type 1 diabetes, T1DM) or insulin sensitivity (Type 2 diabetes, T2DM), is known to involve the excess accumulation of "poorly folded proteins", namely, the induction of pathogenic ER stress in pancreatic β-cells. ER stress is known to contribute to the dysfunction of the insulin-producing pancreatic β-cells. T1DM and T2DM are multifactorial diseases, especially T2DM; both environmental and genetic factors are involved in …


Reflection On Best Practices In Designing Online Middle Level Learning, Holly J. Thornton Dec 2022

Reflection On Best Practices In Designing Online Middle Level Learning, Holly J. Thornton

Current Issues in Middle Level Education

An increase in online learning during the pandemic has led to new thinking about online instruction that will last far beyond the pandemic. The hurried nature of instructional design as the pandemic shifted teaching and learning from the classroom to the computer may have neglected the need to design lessons using best practices online instead of focusing on content delivery and grading. Practices that are part of successful middle level education including cultivating depth of student understanding, developmental responsiveness, social emotional learning and differentiation to meet young adolescent student needs may have been neglected in pandemic online lesson design. This …


Examining Teaching And Learning Environments Among Kentucky Schools To Watch And Non-Schools To Watch Schools Using Tell Survey Data, Michael Dicicco, Ryan Alverson Dec 2022

Examining Teaching And Learning Environments Among Kentucky Schools To Watch And Non-Schools To Watch Schools Using Tell Survey Data, Michael Dicicco, Ryan Alverson

Current Issues in Middle Level Education

In 2017, the state of Kentucky distributed the Teaching, Empowerment, Leading, and Learning (TELL) survey to gain an understating of the learning environments in Kentucky schools. Many of the items on the TELL survey addressed key components of the School to Watch criteria and rubric. Researchers were interested in the teaching and learning conditions in Kentucky middle schools that contributed to successful school environments as defined by the Schools to Watch criteria, and to use results from the TELL survey to see what high scoring schools were doing well according to the teachers and principals that completed the survey. Researchers …


Christmas Through Crite's Eyes, Sarah B. Cahalan Dec 2022

Christmas Through Crite's Eyes, Sarah B. Cahalan

Marian Library Blog Archive

As Christmas approaches, the Marian Library’s director reflects on depictions of the Holy Family by one of the 20th century’s most important creators of Christian art, whose works challenge the viewer: “How would God choose to come among us today, and how would the world receive him?”


Managing Artificial Intelligence Projects: Key Insights From An Ai Consulting Firm, Gregory Vial, Ann-Frances Cameron, Tanya Giannelia, Jinglu Jiang Dec 2022

Managing Artificial Intelligence Projects: Key Insights From An Ai Consulting Firm, Gregory Vial, Ann-Frances Cameron, Tanya Giannelia, Jinglu Jiang

Management and Accounting Faculty Scholarship

While organisations are increasingly interested in artificial intelligence (AI), many AI projects encounter significant issues or even fail. To gain a deeper understanding of the issues that arise during these projects and the practices that contribute to addressing them, we study the case of Consult, a North American AI consulting firm that helps organisations leverage the power of AI by providing custom solutions. The management of AI projects at Consult is a multi-method approach that draws on elements from traditional project management, agile practices, and AI workflow practices. While the combination of these elements enables Consult to be effective in …


Vol.50 N.22 December 22nd 2022, Voice Media Ventures Dec 2022

Vol.50 N.22 December 22nd 2022, Voice Media Ventures

Black Voice News

No abstract provided.


Omega Capital Management Partn V. Leonard Schrage Dec 2022

Omega Capital Management Partn V. Leonard Schrage

2022 Decisions

USDC for the District of Delaware


Usa V. Julio Aviles, Sr. Dec 2022

Usa V. Julio Aviles, Sr.

2022 Decisions

USDC for the Middle District of Pennsylvania


Realizing Molecular Machine Learning Through Communications For Biological Ai: Future Directions And Challenges, Sasitharan Balasubramaniam, Samitha Somathilaka, Sehee Sun, Adrian Ratwatte, Massimiliano Pierobon Dec 2022

Realizing Molecular Machine Learning Through Communications For Biological Ai: Future Directions And Challenges, Sasitharan Balasubramaniam, Samitha Somathilaka, Sehee Sun, Adrian Ratwatte, Massimiliano Pierobon

School of Computing: Faculty Publications

Artificial Intelligence (AI) and Machine Learning (ML) are weaving their way into the fabric of society, where they are playing a crucial role in numerous facets of our lives. As we witness the increased deployment of AI and ML in various types of devices, we benefit from their use into energy-efficient algorithms for low powered devices. In this paper, we investigate a scale and medium that is far smaller than conventional devices as we move towards molecular systems that can be utilized to perform machine learning functions, i.e., Molecular Machine Learning (MML). Fundamental to the operation of MML is the …


Surgical Intervention For Endobronchial Tuberculosis With Total Bronchial Occlusion: A Case Report, Muhammad A. Putra, Matthew Billy, Radhyaksa Ardaya, Rut Hp Ekasiwi, Sari Rahmawati, Karel Hs Sumarsudi Dec 2022

Surgical Intervention For Endobronchial Tuberculosis With Total Bronchial Occlusion: A Case Report, Muhammad A. Putra, Matthew Billy, Radhyaksa Ardaya, Rut Hp Ekasiwi, Sari Rahmawati, Karel Hs Sumarsudi

The New Ropanasuri Journal of Surgery

Introduction. Endobronchial Tuberculosis (EBTB) is a specific TB form affecting the tracheobronchial tree with microbial and histopathological evidence. Early diagnosis is essential to provide timely treatment and prevent complications but also proves difficult due to the low positive rate of acid–fast bacilli (AFB) staining of sputum smears and non–specific clinical and radiological findings.

Case Illustration. We reported a 19–year–old man with a productive cough suspected of pulmonary tuberculosis, with a positive GeneXpert test and negative AFB smear. He received anti–tuberculosis drugs for six months. Although the symptoms initially seemed to improve, the patient complained of dyspnea during moderate activities in …


Transplantation In Pediatrics Liver Failure Associated With Acute Hepatitis Of Unknown Etiology, Afid B. Putra, Agi S. Putranto, Muftah Risyaldi, Luthfian A. Nurachman Dec 2022

Transplantation In Pediatrics Liver Failure Associated With Acute Hepatitis Of Unknown Etiology, Afid B. Putra, Agi S. Putranto, Muftah Risyaldi, Luthfian A. Nurachman

The New Ropanasuri Journal of Surgery

Introduction. On 5th April 2022, some cases of severe acute hepatitis of unknown etiology in children were reported in the United Kingdom. Since then, the number has increased rapidly, with 650 probable cases identified worldwide. This review focuses on available information about managing acute liver failure (ALF) in pediatrics with acute hepatitis of unknown etiology through the perspective of hepatobiliary surgery.

Method. A literature review proceeded on some databases, namely PubMed and Google Scholar. Epidemiological data and technical policy were obtained from World Health Organization and some government institutions.

Results. Severe acute hepatitis can progressively develop into acute liver …


Use Of An Invertebrate Animal Model (Aplysia Californica) To Develop Novel Neural Interfaces For Neuromodulation, Junqi Zhuo, Jeffrey P. Gill, Michael W. Jenkins, Hillel J. Chiel Dec 2022

Use Of An Invertebrate Animal Model (Aplysia Californica) To Develop Novel Neural Interfaces For Neuromodulation, Junqi Zhuo, Jeffrey P. Gill, Michael W. Jenkins, Hillel J. Chiel

Faculty Scholarship

New tools for monitoring and manipulating neural activity have been developed with steadily improving functionality, specificity, and reliability, which are critical both for mapping neural circuits and treating neurological diseases. This review focuses on the use of an invertebrate animal, the marine mollusk Aplysia californica, in the development of novel neurotechniques. We review the basic physiological properties of Aplysia neurons and discuss the specific aspects that make it advantageous for developing novel neural interfaces: First, Aplysia nerves consist only of unmyelinated axons with various diameters, providing a particularly useful model of the unmyelinated C fibers in vertebrates that are known …


Aptamer Proteomics Of Serum Exosomes From Patients With Primary Raynaud's And Patients With Raynaud's At Risk Of Evolving Into Systemic Sclerosis, Sonsoles Piera-Velazquez, Simon T. Dillon, Xuesong Gu, Towia A. Libermann, Sergio A. Jimenez Dec 2022

Aptamer Proteomics Of Serum Exosomes From Patients With Primary Raynaud's And Patients With Raynaud's At Risk Of Evolving Into Systemic Sclerosis, Sonsoles Piera-Velazquez, Simon T. Dillon, Xuesong Gu, Towia A. Libermann, Sergio A. Jimenez

Department of Dermatology and Cutaneous Biology Faculty Papers

BACKGROUND: A major unmet need for Systemic Sclerosis (SSc) clinical management is the lack of biomarkers for the early diagnosis of patients with Raynaud's Phenomenon at high risk of evolving into SSc.

OBJECTIVE: To identify proteins contained within serum exosomes employing an aptamer proteomic analysis that may serve to reveal patients with Raynaud's Phenomenon at risk of developing SSc.

METHODS: Exosomes were isolated from serum samples from patients with Primary Raynaud's Phenomenon and from patients with Raynaud's Phenomenon harbouring serum antinuclear antibodies (ANA) who may be at high risk of evolving into SSc. The expression of 1,305 proteins was quantified …