Digital Commons Network^™

Gabra5 Plays A Sexually Dimorphic Role In Pomc Neuron Activity And Glucose Balance, Zhou Pei, Yang He, Jonathan C Bean, Yongjie Yang, Hailan Liu, Meng Yu, Kaifan Yu, Ilirjana Hyseni, Xing Cai, Hesong Liu, Na Qu, Longlong Tu, Kristine M Conde, Mengjie Wang, Yongxiang Li, Na Yin, Nan Zhang, Junying Han, Camille Hs Potts, Nikolas A Scarcelli, Zili Yan, Pingwen Xu, Qi Wu, Yanlin He, Yong Xu, Chunmei Wang

Children’s Nutrition Research Center Staff Publications

Pro-opiomelanocortin (POMC) neurons are important for the regulation of body weight and glucose balance. The inhibitory tone to POMC neurons is mediated primarily by the GABA receptors. However, the detailed mechanisms and functions of GABA receptors are not well understood. The α5 subunit of GABAA receptor, Gabra5, is reported to regulate feeding, and we found that Gabra5 is highly expressed in POMC neurons. To explore the function of Gabra5 in POMC neurons, we knocked down Gabra5 specifically from mature hypothalamic POMC neurons using the clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 strategy. This POMC-specific knock-down of Gabra5 did not affect …

Associations Of Prenatal Phthalate Exposure With Neurobehavioral Outcomes In 45- And 75-Month-Old Infants, Jenna L N Sprowles, Kelsey L C Dzwilewski, Francheska M Merced-Nieves, Salma M A Musaad, Susan L Schantz, Sarah D Geiger

Children’s Nutrition Research Center Staff Publications

Phthalates are ubiquitous endocrine-disrupting chemicals, and research indicates that prenatal exposure to some phthalates may affect neurodevelopment. In a prospective birth cohort study, five first-morning urine samples collected across pregnancy were pooled and the following phthalate biomarkers assessed: sum of di-(2-ethylhexyl) phthalate metabolites (ΣDEHP), sum of diisononyl phthalate metabolites (ΣDINP), sum of dibutyl phthalate metabolites (ΣDBP), sum of anti-androgenic metabolites (ΣAA), monoethyl phthalate (MEP), and sum of all phthalate metabolites (ΣAll). The Ages & Stages Questionnaires® (ASQ), a standardized parent-reported, age-adapted screening tool, measured communication, personal-social, problem solving, and motor domains in infants at 4.5 and 7.5 months (n = …

Tissue-Specific Mechanisms Of Bile Acid Homeostasis And Activation Of Fxr-Fgf19 Signaling In Preterm And Term Neonatal Pigs, Caitlin Vonderohe, Greg Guthrie, Barbara Stoll, Shaji Chacko, Harry Dawson, Douglas G Burrin

Children’s Nutrition Research Center Staff Publications

The tissue-specific molecular mechanisms involved in perinatal liver and intestinal farnesoid X receptor (FXR)-fibroblast growth factor 19 (FGF19) signaling are poorly defined. Our aim was to establish how gestational age and feeding status affect bile acid synthesis pathway, bile acid pool size, ileal response to bile acid stimulation, genes involved in bile acid-FXR-FGF19 signaling and plasma FGF19 in neonatal pigs. Term (n = 23) and preterm (n = 33) pigs were born via cesarean section at 100% and 90% gestation, respectively. Plasma FGF19, hepatic bile acid and oxysterol profiles, and FXR target gene expression were assessed in pigs …

Articulator Q2 2022

Metro Denver Dental Society Articulator Magazine

The MDDS Articulator magazine has been serving as the voice for Denver's dental community for over 100 years.

Distributed to approximately 2,000 dental professionals quarterly, the Articulator features local news, industry trends, practice management guidance, data-driven research and more. The award-winning publication is available to member dentists in both print and digital forms.

Issues include cover and feature articles alongside regular columns with regional news impacting the Metro Denver membership including editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.

N Y State Dent J January 2022

The New York State Dental Journal

In the January 2022 issue, the reader will find the following feature articles:

• A Call to Do Better: Addressing Diversity within the Dental Profession
• Moving on in the New Year
• Destination Dental School: A Remote Pipeline Program to Increase Student Diversity
• Alteration in Facial Contour Associated with Aging

This issue includes regular columns with regional news impacting the New York membership including: editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.

Wyoming’S Wild Horse Ranch: History And Description Of A Socio-Ecological Experiment, Alex Sas-Jaworsky, John Derek Scasta

Human–Wildlife Interactions

The growing population of free-roaming horses (Equus ferus caballus) on western public rangelands has necessitated that federal agencies, such as the Bureau of Land Management (BLM) and U.S. Forest Service, develop novel approaches to curb growth including reproduction management. However, bureaucracy has hindered effective research and application of horse management on public lands and examples on private lands may present new solutions. Here we present the history and current population management strategy for the Wild Horse Ranch (WHR) located in southeastern Wyoming, USA, as an example of an ongoing private entity managing horses. Prior to 1985, this ~6,000-ha …

Health Risk Perceptions Regarding Electronic Nicotine Delivery Systems (Ends) Among Individuals With Respiratory Illnes, Sarah Ann Sebban

Theses and Dissertations

Electronic nicotine delivery systems (ENDS), also known as electronic cigarettes, are portable battery-powered devices used to smoke or “vape” a flavored solution which usually contains nicotine. Many national organizations (CDC, AMA, AAFP, ALA, AHA) have recognized the alarmingly increased rates of ENDS use in the United States, especially among certain populations. Those most likely to engage in ENDS use are youth and young adults, and adults who already smoke combustible cigarettes. Many people perceive ENDS use as a healthier alternative to smoking regular cigarettes and thus, are more willing to initiate ENDS use. However, research has indicated that ENDS use …

Old Minds, New Marketplaces: How Evolved Psychological Mechanisms Trigger Mismatched Food Preferences, Michal Folwarczny, Tobias Otterbring, Valdimar Sigurdsson, Lynn K. L. Tan, Norman P. Li

Research Collection School of Social Sciences

Principally due to unhealthy food choices, almost half of adults worldwide are overweight or obese. Current food retail practices bear some responsibility for such public health issues. We argue that numerous attempts to promote healthy eating have been unsuccessful due to the failure to account for our outdated evolved food selection mechanisms. Building on the evolutionary mismatch hypothesis and contrasting ancestral versus present-day foraging environments, we discuss how marketing activities exploit evolutionarily old food preferences and elicit unhealthy food choices for profit maximization at the expense of public health in terms of food consumption. We conclude by explaining how to …

Shifting Strategies: The Politics Of Radical Change In Provincial Development Policy In China, John A. Donaldson, Xiaotao Yang

Research Collection School of Social Sciences

Why do provincial governments change policy, even when those policies have proven successful? This paper explores a debate regarding the determinants of provincial policy choice and the degree of discretion provinces are permitted in this area. It does so by scrutinizing the shift in Guizhou's development policy from a poverty reduction orientation to a wholehearted pursuit of economic growth, urbanization and industrialization. In contrast to those who argue that central experience, prospects for promotion or local conditions are key factors explaining policy choice, the paper concludes that Guizhou's shift in policy had more to do with the backgrounds and experiences …

The Potential Mediating Effects Of Social Support Network Size And Physical Activity On Cognitive Function And Mortality Risk, Madeline Zipperer

UNF Graduate Theses and Dissertations

BACKGROUND: Low cognitive function has been shown to be an independent predictor of all-cause and cardiovascular disease (CVD)-related mortality. Social support network size and total physical activity volume (TPAV) are two modifiable factors which have been shown to be independently associated with cognitive function and mortality risk. Therefore, the purpose of this study was to examine the potential mediating effects of social support network size and TPAV on cognitive function and all-cause and CVD-related mortality risk in a large, nationally representative sample of U.S. adults.

METHODS: Study sample (N =2,550) included older adult (≥ 60 years of age) participants …

A Two-Day Virtual Workshop On The Micronutrient-Directed Nutrition-Focused Physical Exam For Ghanaian Nutrition Professionals: Examining Perceived Self-Efficacy And Innovation, Leah Anne Qubty

UNF Graduate Theses and Dissertations

Micronutrients are key components of various physiological processes. Therefore, in the setting of deficiency, poor health outcomes ensue. In Ghana, micronutrient deficiencies are common and medical resources are limited. The Ghanaian dietetics profession is growing, and this growth is propitiously timed to address micronutrient deficiencies. Biochemical markers of nutrition status are considered the gold standard to detect micronutrient deficiencies, but are costly and require specialized medical equipment. In the absence of available biochemical markers of nutrition status, the micronutrient-directed nutrition-focused physical exam is a viable tool. Nutrition professionals such as Registered Dietitians are qualified to conduct this exam, but feel …

Knowledge, Attitudes And Practices Of Us-Based Registered Dietitians Regarding Vitamin D As A Key Nutrient In Public Health, Karen S. Basedow

UNF Graduate Theses and Dissertations

Abstract

The purpose of this study was to determine the knowledge, attitude and behavior influences of Registered Dietitians (RDNs) regarding Vitamin D (VD). An electronic questionnaire served as the data collection tool developed using previously validated questions and supplemented with behavior construct questions. Content and face validity was assessed by an expert panel; internal consistency was assessed using Cronbach’s Alpha. Scores were assessed for knowledge to determine dietitian awareness and competency about VD, attitudes of RDNs regarding importance and practices around VD, and influences on RDN behavior including by other healthcare providers (HCP). Relationships between scales for knowledge, attitude and …

The Effects Of Fermented Vegetables On The Gut Microbiota For Prevention Of Cardiovascular Disease, Melissa Baron

UNF Graduate Theses and Dissertations

This study investigated the impact of regular consumption of fermented vegetables on markers of inflammation and the composition of the gut microbiota in adults at increased risk for cardiovascular disease. Eighty-seven adults ages 35-64 were randomized into a Fermented Vegetable (FV) (100g fermented vegetables daily at least 5x/wk), or a Usual Diet (UD) group. Blood and stool samples were obtained before and after the intervention for measurement of C-Reactive Protein, interleukin-6, angiopoietin-like protein 4, trimethylamine oxide, and lipopolysaccharide binding protein. Next-generation sequencing of the V4 region of the 16S rRNA gene isolated from stool samples was performed on the Illumina …

Improving New Market Tax Credit Accessibility To Address Food Vulnerability, Zahraa Nasser

Notre Dame Journal of Law, Ethics & Public Policy

No abstract provided.

Local Power, Alexandra B. Klass, Rebecca Wilton

Vanderbilt Law Review

This Article is about “local power.” We use that term in two distinct but complementary ways. First, local power describes the authority of local governments to enact regulatory policies in the interests of their citizens. Second, local power describes the authority of local governments to exercise proprietary control over the sources and delivery of electric power to their citizens. This dual meaning of local power is particularly important today, as an increasing number of local governments are seriously considering “municipalizing”--taking control of local electric power systems-—at the same time that, outside the electric power sector, many states are constraining local …

Childhood Food Insecurity: A Program Impact And Evaluation Study Of The Meals On Wheels For Kids Program, Claudia Rivero

UNF Graduate Theses and Dissertations

In America, millions of families and children face hunger and food insecurity every day. According to the United States Department of Agriculture, more than thirty-eight million people experienced hunger in 2020. As many as 13 million children in the United States live in food-insecure homes. Many households that experience food insecurity do not qualify for federal nutrition programs. While valuable, barriers to these programs can block food-insecure households with children and prevent access to healthy food. The impact of adverse health and nutritional consequences, of a food-insecure household, will continue to plague our communities until efficient programming connects to those …

Nutrition Perception, Dietary Intake, And Anthropometric Correlations Between Autism Spectrum Disorder And Typically Developing Adolescents., Kristin M. Berg

UNF Graduate Theses and Dissertations

The adolescent’s nutrition perception is reflected in dietary intake and body composition. Obesity is prevalent among adolescents with Autism Spectrum Disorder (ASD). Dietary habits of children with ASD are affected by sensory issues, gastrointestinal factors, and parental provision of diet. This cross-sectional study identifies the relationships among variables for dietary intake, nutrition perception of intake, and anthropometric measurements for adiposity for 19 adolescents, ages 11 to 17, with ASD. Twenty-four children who are typically developing (TD) were assessed to compare all variables for significant differences. Measurements of variables of interest were obtained from the adolescent subjects: a 24-hour recall of …

New Associate Editors, S. Nicole Frey

Human–Wildlife Interactions

Human-Wildlife Interactions journal announces its new associate editors.

Fertility Control Options For Management Of Free-Roaming Horse Populations, Ursula S. Bechert, John W. Turner Jr., Dan L. Baker, Douglas C. Eckery, Jason E. Bruemmer, Candace C. Lyman, Tulio M. Prado, Sarah R. B. King, Mark A. Fraker

Human–Wildlife Interactions

The management of free-roaming horses (Equus ferus) and burros (E. asinus) in the United States has been referred to as a “wicked problem” because, although there are population control options, societal values will ultimately determine what is acceptable and what is not. In the United States, free-roaming equids are managed by different types of organizations and agencies, and the landscapes that these animals inhabit vary widely in terms of access, size, topography, climate, natural resources, flora, and fauna. This landscape diversity, coupled with contemporary socioeconomic and political environments, means that adaptive management practices are needed to …

Dehydration And Mortality Of Feral Horses And Burros: A Systematic Review Of Reported Deaths, John Derek Scasta, Eric Thacker, Jacob D. Hennig, Karl Hoopes

Human–Wildlife Interactions

Water is a requirement for all organisms, including equids. Dehydration-caused mortality of feral horses (Equus ferus caballus) is often cited as a cause of concern and as justification for management of feral horses, yet a paucity of information exists on the matter. We conducted a systematic review from September 1, 2020 through January 15, 2021 of available news reports of feral horse and burro (E. asinus) dehydration mortalities and public interventions to save horses using a public search engine with a priori defined search term combinations and additional snowball sampling. We found 15 uniquely reported mortality …

Administrator Impact: A Survey Of The Relationship Between Self-Efficacy, Mckinney-Vento Legal Literacy, And Program Effectiveness In Ensuring The Educational Stability Of Homeless Youth., Anthony J. Marinello

Graduate Research Theses & Dissertations

The idea that K-12 building leaders should be legally literate in the elements which encapsulate their professional obligations is widely accepted. The degree, however, in which this concept holds true in contemporary systems of education represents an opportunity for further research. While a concrete definition of legal literacy remains up for debate, it has been conceptualized for the better part of half a century when discussions began on its fundamental need (Dunklee & Shoop, 1986). This need has been exacerbated in recent years as we continue to live in an increasingly litigious society. This dissertation examines legal literacy K-12 building …

Teaching And Learning Numeracy In Health Sciences: A High School Health Classroom Case Study, Jasmina Mesic

Graduate Research Theses & Dissertations

High school health science teacher professional development (TPD) is one learning environment where emphasis on numeracy and nutritional health literacy can make lifelong positive impacts on the health and wellbeing of youth. It has been estimated that only 33% of United States adults have limited numeracy skills and that only 12% are health literate. The purpose of this study was to begin the development of a high school health science TPD focused on numeracy and nutritional health literacy and to assist the teacher in delivering subject matter using brain-based learning principles. An exploratory case study design was selected as the …

Nutrient Scarcity And Cellular Cooperation In A Clonal Hydroid, Weam S. El Rahmany

Graduate Research Theses & Dissertations

Biological complexity forms when lower-level units (e.g., genes, cells, organisms) cooperatively band together. This complexity may be exemplified by multicellularity, the cooperation between the cells of the same species, or symbiosis, cooperation between the cells of different species. This cooperation is under continual threat, as defection, the opposite of cooperation, is favored by default by lower-level units (i.e., cells). Animal cancers may be the most well-known phenomena that exemplify the concept of cellular defection. Cancer cells have been shown to feature morphological and metabolic traits, developed through differential gene expression or mutations, that favor their growth at the cost of …

Are Hormones Impacting Weight Gain?, Brannon Blount

All Student-Created Educational Resources

A brochure explaining hormones and weight gain are directly related.

Fresh Fruit And Veggies For Correctional Facilities, Katie Melara

All Student-Created Educational Resources

This handout depicts the benefits of fresh fruit and vegetables for incarcerated people and their communities, with proposed solutions for increasing fresh produce in correctional facilities. The content of this handout is based primarily on information Eating Behind Bars: Ending the Hidden Punishment of Food in Prison Report by Impact Justice.

Hormonal Regulation Of Weight, Tatiana Larionova

All Student-Created Educational Resources

A brochure on the hormonal regulation of weight.

How Hormones Control Your Weight, University Of New England

All Student-Created Educational Resources

A brochure that educates the general pubic on how hormones regulate body weight.

How Do My Hormones Affect My Body Weight?, Cristina Clark

All Student-Created Educational Resources

A Brochure about Hormones and Body Weight

Evaluation Of Plasma Carnitine Status In Patients Diagnosed With Juvenile Idiopathic Arthritis, Ayşe Çi̇ğdem Aktuğlu Zeybek, Ertuğrul Kiykim, Kenan Barut, Tanyel Zübari̇oğlu, Mehmet Şeri̇f Cansever, Özgür Kasapçopur

Turkish Journal of Medical Sciences

No abstract provided.

Curriculum Development Of Agricultural Educators In South Dakota, Mercedes Lemke

Electronic Theses and Dissertations

Curriculum development is an essential component of teaching. Understanding how agriculture education teachers utilize, develop, and adapt content to curriculum can benefit teachers to spend less time on curriculum development. Recognizing the way agriculture education teachers use content in curriculum implementation will allow curriculum developers to create materials that can effectively be used by teachers. This study also looked at the affects of how COVID19 pandemic affected the way teachers locate and develop curriculum. The purpose of this study was to evaluate the way agriculture education instructor’s usage of content for curriculum development, implementation decisions and the affects of the …