Digital Commons Network^™

Rsif Ghana Country Report 2022, Regional Scholarship And Innovation Fund (Rsif)

Rsif Country Progress Reports

Ghana contributed USD 2 million to Rsif in 2020. Ghana is the current vice-chair of PASET. There are 22 competitively selected Ghanaian Rsif doctoral scholars (23% women) in four thematic areas in seven different Rsif African Host Universities across the continent. There are so far 1 Ghanaian Rsif alumni and 12 publications by Ghanaian Rsif students. University of Ghana (UG) was competitively selected as an Rsif African Host University in food security and agribusiness in 2019 (PhD Program in Applied Agricultural and Policy/Agribusiness). UG is hosting 29 Rsif funded PhD students (38% women) from ten different nationalities. Seven Rsif funded …

Molecular Mechanisms Underlying Aberrant Circulating Steroid Hormones In Gnrhr-Ii Knockdown Boars And Their Control Littermates, Dorothy H. Elsken

Department of Animal Science: Dissertations, Theses, and Student Research

Swine are the only livestock species that produce a functional protein for both GnRH-II and its receptor (GnRHR-II). Our laboratory reported that the interaction between GnRH-II and GnRHR-II facilitates testosterone production, independent of LH stimulation. To further examine GnRHR-II function, we developed a swine line with 70% reduced GnRHR-II mRNA levels (GnRHR-II KD) compared to control littermates. Mass spectrometry analysis of serum revealed that circulating levels of gonadal steroids were reduced in mature transgenic vs. control boars. Paradoxically, evaluation of testicular tissue indicated no difference between lines for gonadal steroid hormone levels. To address a potential cause for this discrepancy, …

Impacts Of Feeding Biochar To Beef Cattle On Greenhouse Gas Emissions And Performance And Characterizing Yearling Steers Grazing Smooth Bromegrass Pasture Using Gps, Holly A. Heil

Department of Animal Science: Dissertations, Theses, and Student Research

As global warming continues to rise, the pressure and growing demand for sustainable animal production is increasing. Livestock naturally produce greenhouse gas emissions through enteric fermentation. Dietary manipulation strategies have been sought out to decrease emissions in ruminants using feed additives.

Two independent finishing feedlot experiments evaluated two types of biochar and its effects on animal performance, carcass characteristics and greenhouse gas emissions. Experiment 1 utilized pistachio shell biochar and experiment 2 utilized biochar sourced from ponderosa pine wood waste, both types included at 1% of the diet DM. The addition of biochar to the diet did not impact animal …

The Nebraska 4-H Equine Advancement Level Program’S Role In Positive Youth Development Using The Five Cs Model: An Exploratory Study, Eunhye Mccarthy

Department of Animal Science: Dissertations, Theses, and Student Research

Positive youth development (PYD) focuses on developing the strengths of youth through positive activities and behaviors rather than reducing negative tendencies. A well-researched model of PYD is the five C’s model that is popularly used in youth development organizations such as 4-H. The Nebraska 4-H Equine Advancement Level program was intended to serve as a guidebook for instruction and assessment of youth as they learn more about horses and horsemanship skills. Each of the four levels has an emphasis in developing a 4-H member’s responsibility, self-discipline, self-reliance, patience, and pride of accomplishments. The program was started approximately 30 years ago …

Environmental Determination Of Gastrointestinal Parasitism In Katahdin Sheep, Brian Arisman

Department of Animal Science: Dissertations, Theses, and Student Research

Gastrointestinal nematodes (GIN) negatively affect the performance and wellbeing of sheep and are difficult to control due to anthelmintic resistance. Producers are therefore choosing breeds naturally resistant to GIN infection, such as the Katahdin. Katahdin are raised in various climates and management systems in the U.S., and those environmental factors can be combined into eco-management clusters. We hypothesized that GIN challenge varies predictably based on the characteristics of these clusters. Katahdin producers from across the U.S. were surveyed for management information. Body weights (BW), fecal egg counts (FEC) and FAMACHA scores (FAM) were collected on 3,527 Katahdin lambs around 90 …

Evaluation Of Nutritional Factors Affecting Sow Reproductive Longevity, J'Nan E. Wittler

Department of Animal Science: Dissertations, Theses, and Student Research

Sow reproductive longevity is an important trait for swine operations from a production and economic standpoint. Previous research has shown that a sow needs to produce 3 litters before she covers the costs associated with introducing her to the operation. A literature review of research conducted related to sow longevity is discussed in Chapter 1. Chapters 2 and 3 present data from the University of Nebraska – Lincoln’s long-term sow longevity research. The research looks at the effects of energy restriction with soy hulls during gilt development on sow reproductive longevity through 4 parities. Chapter 2 presents data from replications …

Students' Perceptions Of Online Equine Courses And Their Impacts On Learning Outcomes, Blaire L. (Gibbens) Speck

Department of Animal Science: Dissertations, Theses, and Student Research

Post-secondary education is always changing and evolving. Over the last few years, significant changes in education have resulted in an increased number of online courses. Approximately 28% of students seeking higher education participate in at least one online course and 14% are enrolled exclusively in distance or online programs (Allen & Seaman, 2016). However, courses that are typically hands-on, like equine science, may be more challenging online. The hands-on experiences in equine science classes help prepare students for future careers. Due to an increase in students choosing to take courses online, a review of online teaching methods was conducted to …

Wild Foods Contribute To Higher Dietary Diversity In India (Dataset And Code), Jennifer Zavaleta Cheek

NRM Departmental Data Sets

This data set and code files are in relation to a submitted research article with the working title : Wild foods contribute to higher dietary diversity in India

Article abstract:

Wild foods, from forests and common lands, can contribute to food and nutrition security. Most previous studies have established correlations between wild food consumption and children’s dietary diversity in Africa, but other groups and geographic contexts remain understudied. Here, a rigorous quasi-experimental method was combined with monthly-interval data to assess the contribution of wild foods to women’s diets. We collected 24-hour diet recall data monthly, from November 2016 to November …

Pregnancy And Childbirth: Male Partner Involvement In Uasin Gishu, Kenya, Kamau Tabitha, Roselyter Riang’A, Mwanzia Lydia, Buluku Elizabeth, Sawe Caroline, Wambugu Beth, Patel Kirtika, Mutai Judith, Pauline Mwenje, Kemboi Sharon

Population Health, East Africa

Introduction: In many African countries, pregnancy and childbirth has traditionally beenregarded as a woman’s affair. As a result, male partner involvement and participationin pregnancy and childbirth has been minimal, which is thought to have contributed tothe high rate of maternal and neonatal morbidities and mortalities. Male partners areoften key decision-makers in African households for cultural reasons, yet their role inpregnancy and childbirth is not clearly defined. The aim of this study was to examine anddocument male partner involvement in maternal healthcare in Kenya.

Methods: A health facility-based cross-sectional descriptive study design was used.Systematic random sampling was used to …

A Phase Ii Randomized Double Blinded Trial Evaluating The Efficacy Of Curcumin With Pre-Operative Chemoradiation For Rectal Cancer, Jillian R Gunther, Awalpreet S Chadha, Sushovan Guha, Gottumukkala S Raju, Dipen M Maru, Mark F Munsell, Yan Jiang, Peiying Yang, Edd Felix, Marilyn Clemons, Geena George Mathew, Pankaj K Singh, John M Skibber, Miguel A Rodriguez-Bigas, George J Chang, Cathy Eng, Marc E Delclos, Christopher H Crane, Prajnan Das, Sunil Krishnan

Faculty, Staff and Student Publications

Background

In vivo studies demonstrate that curcumin increases radioresponse of colorectal cancers. To demonstrate efficacy in humans, we performed a randomized double-blind study of locally advanced rectal cancer (LARC) patients receiving pre-operative chemoradiation therapy (CRT) ± curcumin. We used pathologic complete response (pCR) rate as a surrogate for clinical outcome.

Methods

From 2008–2010, LARC patients were randomized to placebo/curcumin in a 1:2 ratio. Patients received CRT [50.4 gray in 28 fractions; capecitabine (825 mg/m² twice daily)] followed by surgery. Curcumin (4 grams orally, twice daily) or placebo was given throughout CRT and 6 weeks afterward. Toxicity was monitored weekly. …

Clinically Significant Metachronous Colorectal Pathology Detected Among Young-Onset Colorectal Cancer Survivors: Implications For Post-Resection Surveillance Guidelines, Oliver Peacock, Eduardo Vilar, Montserrat Guraieb-Trueba, Selvi Thirumurthi, George J Chang, Y Nancy You

Faculty, Staff and Student Publications

No abstract provided.

Liver Injury After Sars‐Cov‐2 Vaccination: Features Of Immune-Mediated Hepatitis, Role Of Corticosteroid Therapy And Outcome, Cumali Efe, Anand V Kulkarni, Benedetta Terziroli Beretta-Piccoli, Bianca Magro, Albert Stättermayer, Mustafa Cengiz, Daniel Clayton-Chubb, Craig Lammert, Christine Bernsmeier, Özlem Gül, Fatima Higuera-De La Tijera, Margarita Anders, Ellina Lytvyak, Mete Akın, Tugrul Purnak, Rodrigo Liberal, Mirta Peralta, Berat Ebik, Serkan Duman, Nurhan Demir, Yasemin Balaban, Álvaro Urzua, Fernando Contreras, Maria Grazia Venturelli, Yılmaz Bilgiç, Adriana Medina, Marcos Girala, Fulya Günşar, Maria-Carlota Londoño, Theodoros Androutsakos, Ayelen Kisch, Alper Yurci, Fatih Güzelbulut, Yasir Furkan Çağın, Enver Avcı, Murat Akyıldız, Emine Kübra Dindar-Demiray, Murat Harputluoğlu, Rahul Kumar, Sanjaya K Satapathy, Manuel Mendizabal, Marcelo Silva, Stefano Fagiuoli, Stuart K Roberts, Neşe Karadağ Soylu, Ramazan Idilman, Eric M Yoshida, Aldo J Montano-Loza, George N Dalekos, Ezequiel Ridruejo, Thomas D Schiano, Staffan Wahlin

Faculty, Staff and Student Publications

BACKGROUND AND AIMS: A few case reports of autoimmune hepatitis-like liver injury have been reported after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination. We evaluated clinical features, treatment response and outcomes of liver injury following SARS-CoV-2 vaccination in a large case series.

APPROACH AND RESULTS: We collected data from cases in 18 countries. The type of liver injury was assessed with the R-value. The study population was categorized according to features of immune-mediated hepatitis (positive autoantibodies and elevated immunoglobulin G levels) and corticosteroid therapy for the liver injury. We identified 87 patients (63%, female), median age 48 (range: 18-79) …

A Cluster-Randomized Controlled Trial Of Automated Internet Weight-Loss Programs In Primary Care: Role Of Automated Provider Feedback, Deborah F Tate, Jennifer L Kraschnewski, Caitlin Martinez, Molly Diamond, Susan Veldheer, Kevin O Hwang, Erik B Lehman, Chengwu Yang, Christopher N Sciamanna

Faculty, Staff and Student Publications

OBJECTIVE: Despite the high prevalence of obesity and associated health risks in the United States adult population, few primary care providers (PCPs) have time and training to provide weight-management counseling to their patients. This study aims to compare the effect of referral to a comprehensive automated digital weight-loss program, with or without provider email feedback, with usual care on weight loss in patients with overweight or obesity.

METHODS: A total of 550 adults (mean [SD], 51.4 [11.2] years, BMI = 35.1 [5.5] kg/m

RESULTS: Weight changes (mean [SE]) at 12 months were -0.92 (0.46), -3.68 (0.46), and -3.58 (0.48) kg …

A Phase Ii Randomized Double Blinded Trial Evaluating The Efficacy Of Curcumin With Pre-Operative Chemoradiation For Rectal Cancer, Jillian R Gunther, Awalpreet S Chadha, Sushovan Guha, Gottumukkala S Raju, Dipen M Maru, Mark F Munsell, Yan Jiang, Peiying Yang, Edd Felix, Marilyn Clemons, Geena George Mathew, Pankaj K Singh, John M Skibber, Miguel A Rodriguez-Bigas, George J Chang, Cathy Eng, Marc E Delclos, Christopher H Crane, Prajnan Das, Sunil Krishnan

Faculty, Staff and Student Publications

Background: In vivo studies demonstrate that curcumin increases radioresponse of colorectal cancers. To demonstrate efficacy in humans, we performed a randomized double-blind study of locally advanced rectal cancer (LARC) patients receiving pre-operative chemoradiation therapy (CRT) ± curcumin. We used pathologic complete response (pCR) rate as a surrogate for clinical outcome.

Methods: From 2008-2010, LARC patients were randomized to placebo/curcumin in a 1:2 ratio. Patients received CRT [50.4 gray in 28 fractions; capecitabine (825 mg/m2 twice daily)] followed by surgery. Curcumin (4 grams orally, twice daily) or placebo was given throughout CRT and 6 weeks afterward. Toxicity was monitored weekly. Blood …

Violation Of The Rights Of Older Adults, Genaro Vinicio Jordán Naranjo, Nelly Valeria Vinueza Ochoa, Mónica Del Roció Mosquera Endara, Jessica Johanna Santander Moreno

Neutrosophic Sets and Systems

No abstract provided.

Neutrosophic Statistical Analysis Of Behavioral Medicine Knowledge In University Students, Kenia Mariela Peñafiel Jaramillo, Denisse Isabel Suaste Pazmiño, Alex Ramón Valencia Herrera

Neutrosophic Sets and Systems

No abstract provided.

Svns-Based Multicriteria Methods For The Selection Of Management Elements For Academic Diplomacy, Otto Federico Von Feigenblatt

Neutrosophic Sets and Systems

No abstract provided.

Use Of Neutrosophy In The Evaluation Of A Health Education Program For Undergraduate Medical Students, Andrea Suárez López, María Isabel Fong Betancourt, Diana Lorena Jordán Fiallos

Neutrosophic Sets and Systems

No abstract provided.

Neutrosophic Statistical Analysis Of Self-Assessment Of Rehabilitation Knowledge In University Students, Elizabeth Cristina Mayorga Aldaz, Rosita Elizabeth Olivo Torres, Silvia Tatiana Tite Andi, Flor Betzabet Morocho Quinchuela

Neutrosophic Sets and Systems

No abstract provided.

Neutrosophic Linguistic Scale For The Assessment Of Knowledge Of Natural And Traditional Medicine In Dental Students, Rolando Manuel Benites, Jorge David Morales Cobos, Javier Estuardo Sánchez Sánchez

Neutrosophic Sets and Systems

No abstract provided.

Neutrosophic Analysis Of Nutritional Orientation In University Students, María Gabriela Balarezo García, Andrés Eduardo Gallegos Cobo, Miguel Eduardo Ramos Argilagos

Neutrosophic Sets and Systems

No abstract provided.

Closing The Digital Divide, Maria Schlotthauer

Capstone Projects and Master's Theses

The Family Resource Collective is a program under Community Bridges. Serving approximately 5,800 clients per year, the FRC helps the senior community of Santa Cruz County access resources.

There is a huge digital divide within the senior community. The Capstone Project titled ‘Closing the Digital Divide’ will directly address the issue that is now a national crisis. This project will focus on creating several pieces of educational material to aid older individuals in their journey to becoming more technologically savvy. The project teams expect to be able to have materials readily available for all those in need.

In the future, …

Recognition Of Childrens’ Benefits While Participating In Sports To Parents, Melida Carmona

Capstone Projects and Master's Theses

This capstone project focuses on the development of life skills through children’s participation in sports activities. Involving the success and failures involving, technology, social media and its effect on the human mind and body.

Assessment Of Disease Severity And Quality Of Life In Patients With Atopic Dermatitis From South Korea, Sang Wook Son, Ji Hyun Lee, Jiyoung Ahn, Sung Eun Chang, Eung Ho Choi, Tae Young Han, Yong Hyun Jang, Hye One Kim, Moon-Bum Kim, You Chan Kim, Hyun Chang Ko, Joo Yeon Ko, Sang Eun Lee, Yang Won Lee, Bark-Lynn Lew, Chan Ho Na, Chang Ook Park, Chun Wook Park, Kui Young Park, Kun Park, Young Lip Park, Joo Young Roh, Young-Joon Seo, Min Kyung Shin, Sujin Lee, Sang Hyun Cho

Faculty, Staff and Student Publications

BACKGROUND: Data illustrating the impact of atopic dermatitis (AD) on lives of adults with AD in South Korea are limited.

OBJECTIVE: To assess the AD disease severity and its impact on quality of life (QoL) in patients with AD from South Korea.

METHODS: Patients with AD utilizing the specialist dermatology services of major hospitals in South Korea were assessed for disease severity using Eczema Area and Severity Index (EASI) score, for QoL using Dermatology Life Quality Index (DLQI) (for QoL), and for comorbidities and treatment experience via retrospective review of 12-month medical records. Clinical and sociodemographic characteristics were also measured. …

Activated B Cells Suppress T-Cell Function Through Metabolic Competition, Nobuhiko Imahashi, Rafet Basar, Yuefan Huang, Fang Wang, Natalia Baran, Pinaki Prosad Banerjee, Junjun Lu, Ana Karen Nunez Cortes, Nadima Uprety, Emily Ensley, Luis Muniz-Feliciano, Tamara J Laskowski, Judy S Moyes, May Daher, Mayela Mendt, Lucila N Kerbauy, Mayra Shanley, Li Li, Francesca Lorraine Wei Inng Lim, Hila Shaim, Ye Li, Marina Konopleva, Michael Green, Jennifer Wargo, Elizabeth J Shpall, Ken Chen, Katayoun Rezvani

Faculty, Staff and Student Publications

BACKGROUND: B cells play a pivotal role in regulating the immune response. The induction of B cell-mediated immunosuppressive function requires B cell activating signals. However, the mechanisms by which activated B cells mediate T-cell suppression are not fully understood.

METHODS: We investigated the potential contribution of metabolic activity of activated B cells to T-cell suppression by performing in vitro experiments and by analyzing clinical samples using mass cytometry and single-cell RNA sequencing.

RESULTS: Here we show that following activation, B cells acquire an immunoregulatory phenotype and promote T-cell suppression by metabolic competition. Activated B cells induced hypoxia in T cells …

Potential Distribution Of Fall Armyworm In Africa And Beyond, Considering Climate Change And Irrigation Patterns, Bipana Paudel Timilsena, Saliou Niassy, Emily Kimathi, Elfatih M. Abdel-Rahman, Irmgard Seidl-Adams, Mark Wamalwa, Henri E.Z. Tonnang, Sunday Ekesi, David P. Hughes, Edwin G. Rajotte, Sevgan Subramanian

All Peer-Reviewed Publications

The fall armyworm, Spodoptera frugiperda (FAW), first invaded Africa in 2016 and has since become established in many areas across the continent where it poses a serious threat to food and nutrition security. We re-parameterized the existing CLIMEX model to assess the FAW global invasion threat, emphasizing the risk of transient and permanent population establishment in Africa under current and projected future climates, considering irrigation patterns. FAW can establish itself in almost all countries in eastern and central Africa and a large part of western Africa under the current climate. Climatic barriers, such as heat and dry stresses, may limit …

Allergic Sensitization Pattern In The Korean Dermatologic Patients, Yujin Han, Yu Ri Woo, Hei Sung Kim, Jeong Deuk Lee, Sookhee Choi, Jeesuk Yu, Sang Hyun Cho

Faculty, Staff and Student Publications

BACKGROUND: Avoiding causative allergens is important for controlling the clinical course of allergic diseases. Allergen sensitization is influenced by many factors including the environment and lifestyle. The socioeconomic development, climate, and lifestyle changes have increased the prevalence of allergic diseases worldwide. However, there is little information about changes in the trend of the common allergens over time.

OBJECTIVE: This study was aimed at identifying the trends of the common allergens in Korea over a 10-year period based on the results of the multiple allergosorbent test chemiluminescent assay (MAST-CLA).

METHODS: We retrospectively reviewed the medical records of 5,760 patients aged ≥18 …

Comparative Analysis Of Conformational Transition Pathways In Homologous Proteins, Dylan Sebastien Ogden

Graduate Theses and Dissertations

Molecular dynamics (MD) simulations are routinely used to study the dynamics of proteins. However, conventional MD limited to the sampling of local conformational changes as the functionally important conformational transitions of proteins often extend beyond the timescales of the simulations employed, for example, membrane transport proteins. We have determined the combination of multiple MD based techniques that allows for a rigorous characterization of energetics and kinetics of large-scale conformational changes in membrane proteins. The methodology is based on biased, nonequilibrium collective variable based simulations including nonequilibrium pulling, string method with swarms of trajectories, bias-exchange umbrella sampling, and rate estimation techniques. …

The Impact Of Funds Of Knowledge On Elementary Multilingual Learners’ Perceptions Of Their Connection To Their Teacher And The Classroom, Kelli Lowe

All Dissertations

The U.S. population is rapidly becoming more culturally and linguistically diverse, and the education system is ill-equipped to meet the needs of these diverse learners thus creating large achievement gaps. In South Carolina, two factors contributing to an inadequate education system are the lack of teacher preparation programs that address cultural diversity and a predominantly White teacher workforce for an ever-growing diverse student body. The combination of these two factors is particularly detrimental to multilingual learners in the most critical time of a child’s development. This qualitative study was part of a collaboration and combined improvement science with design thinking …

Enhancing Amino Acid Utilization For Broiler Chickens Under Different Scenarios Of Dietary Protein Reduction And Subclinical Coccidiosis, Derrell Trevor Lee

Graduate Theses and Dissertations

Five experiments were conducted to evaluate responses of broiler chickens fed diets with different dietary amino acid (AA) levels when fed normal and reduced dietary crude protein (RCP) diets and reared under different coccidiosis control programs. In the studies with the use of RCP diets, the relationship between dietary Gly + Ser and the Met:Cys ratio was investigated. Experiment 1 evaluated broilers in 2 coccidiosis control programs (live vaccine or in-feed zoalene) and fed increased dietary AA derived from soybean meal or unbound sources from 0-40 d. Vaccination impaired young (0-26 d) broiler body weight gain (BWG) and feed conversion …