Digital Commons Network^™

Recent Advances In Probiotic Application In Animal Health And Nutrition: A Review, Sarayu Bhogoju, Samuel Nahashon

Agricultural and Environmental Sciences Faculty Research

Biotechnological advances in animal health and nutrition continue to play a significant role in the improvement of animal health, growth, and production performance. These biotechnological advancements, especially the use of direct-fed microbials, also termed probiotics, those genetically modified and otherwise, have minimized many challenges facing livestock production around the world. Such advancements result in healthy animals and animal products, such as meat, for a growing population worldwide. Increasing demand for productivity, healthy animals, and consumer food safety concerns, especially those emanating from excessive use of antibiotics or growth promoters, are a driving force for investing in safer alternatives, such as …

Healthy Heart, Healthy You: Nutrition Tips For American Heart Month, Staff

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No abstract provided.

What Have We Learnt From Quantitative Case Reports Of Acute Lateral Ankle Sprains Injuries And Episodes Of 'Giving-Way' Of The Ankle Joint, And What Shall We Further Investigate?, Filip Gertz Lysdal, Yuehang Wang, Eamonn Delahunt, Dominic Gehring, Kyle B. Kosik, Tron Krosshaug, Yumeng Li, Kam-Ming Mok, Kati Pasanen, Alexandria Remus, Masafumi Terada, Daniel T. P. Fong

Athletic Training and Clinical Nutrition Faculty Publications

Lateral ankle sprains are a commonly incurred injury in sports. They have a high recurrence rate and can lead to the development of persistent injury associated symptoms. We performed a quantitative synthesis of published case reports documenting the kinematics of acute lateral ankle sprains and episodes of ‘giving-way’ of the ankle joint to provide a comprehensive description of the mechanisms. A systematic literature search was conducted to screen records within MEDLINE® and EMBASE®. Additional strategies included manual search of specific journals, as well as contacting researchers in relevant communities to retrieve unpublished data. Twenty-four cases were included in the quantitative …

Understanding Information Needs And Barriers To Accessing Health Information Across All Stages Of Pregnancy: Systematic Review, Yu Lu, Laura A Barrett, Rebecca Z Lin, Muhammad Amith, Cui Tao, Zhe He

Open Access Publications

BACKGROUND: Understanding consumers' health information needs across all stages of the pregnancy trajectory is crucial to the development of mechanisms that allow them to retrieve high-quality, customized, and layperson-friendly health information.

OBJECTIVE: The objective of this study was to identify research gaps in pregnancy-related consumer information needs and available information from different sources.

METHODS: We conducted a systematic review of CINAHL, Cochrane, PubMed, and Web of Science for relevant articles that were published from 2009 to 2019. The quality of the included articles was assessed using the Critical Appraisal Skills Program. A descriptive data analysis was performed on these articles. …

The Effects Of Nuclear Factor Erythroid 2 (Nfe2)-Related Factor 2 (Nrf2) Activation In Preclinical Models Of Peripheral Neuropathic Pain, Paramita Basu, Dayna L. Averitt, Camelia Maier, Arpita Basu

Kinesiology and Nutrition Sciences Faculty Research

Oxidative stress, resulting from an imbalance between the formation of damaging free radicals and availability of protective antioxidants, can contribute to peripheral neuropathic pain conditions. Reactive oxygen and nitrogen species, as well as products of the mitochondrial metabolism such as superoxide anions, hydrogen peroxide, and hydroxyl radicals, are common free radicals. Nuclear factor erythroid 2 (NFE2)-related factor 2 (Nrf2) is a transcription factor encoded by the NFE2L2 gene and is a member of the cap ‘n’ collar subfamily of basic region leucine zipper transcription factors. Under normal physiological conditions, Nrf2 remains bound to Kelch-like ECH-associated protein 1 in the cytoplasm …

Recent Advances In Probiotic Application In Animal Health And Nutrition: A Review, Sarayu Bhogoju, Samuel Nahashon

Internal Medicine Faculty Publications

Biotechnological advances in animal health and nutrition continue to play a significant role in the improvement of animal health, growth, and production performance. These biotechnological advancements, especially the use of direct-fed microbials, also termed probiotics, those genetically modified and otherwise, have minimized many challenges facing livestock production around the world. Such advancements result in healthy animals and animal products, such as meat, for a growing population worldwide. Increasing demand for productivity, healthy animals, and consumer food safety concerns, especially those emanating from excessive use of antibiotics or growth promoters, are a driving force for investing in safer alternatives, such as …

Effects Of Three Different Modes Of Resistance Training On Appetite Hormones In Males With Obesity, Ali Ataeinosrat, Marjan Mosalman Haghighi, Hossein Abednatanzi, Mohammad Soltani, Abbass Ghanbari-Niaki, Akbar Nouri-Habashi, Sadegh Amani-Shalamzari, Ali Mossayebi, Mitra Khademosharie, Kelly E. Johnson, Trisha A. Vandusseldorp, Ayoub Saeidi, Hassane Zouhal

Kinesiology

Purpose: This study explored the effect of three different modes of resistance training on appetite hormones [leptin, ghrelin, cholecystokinin (CCK), glucagon-like peptide-1 (GLP-1), and peptide tyrosine–tyrosine (PYY)], cardiometabolic and anthropometric measures in males with obesity. Methods: Forty-four males with obesity (age: 27.5 ± 9.4 yrs.; mean weight: 93.2 ± 2.2 kg, body mass index: 32.9 ± 1.2 kg/m²) were randomized to traditional resistance training (TRT, n = 11), circuit resistance training (CRT, n = 11), interval resistance training (IRT, n = 11) or control (C, n = 11) groups. All resistance training groups received 50 min of supervised …

Role Of Body Mass And Physical Activity In Autonomic Function Modulation On Post-Covid-19 Condition: An Observational Subanalysis Of Fit-Covid Study, Ana Paula Coelho Figueira Freire, Fabio Santos Lira, Ana Elisa Von Ah Morano, Telmo Pereira, Manuel-João Coelho-E-Silva, Armando Caseiro, Diego Giullano Destro Christofaro, Osmar Marchioto Júnior, Gilson Pires Dorneles, Luciele Guerra Minuzzi, Ricardo Aurino Pinho, Bruna Spolador De Alencar Silva

All Faculty Scholarship for the College of Education and Professional Studies

The harmful effects of coronavirus disease 2019 (COVID-19) can reach the autonomic nervous system (ANS) and endothelial function. Therefore, the detrimental multiorgan effects of COVID-19 could be induced by deregulations in ANS that may persist after the acute SARS-CoV-2 infection. Additionally, investigating the differences in ANS response in overweight/obese, and physically inactive participants who had COVID-19 compared to those who did not have the disease is necessary. The aim of the study was to analyze the autonomic function of young adults after mild-to-moderate infection with SARS-CoV-2 and to assess whether body mass index (BMI) and levels of physical activity modulates …

Changes In Apolipoprotein Abundance Dominate Proteome Responses To Prolonged Fasting In Elephant Seals, Jane I. Khudyakov, Rachel R. Holser, Craig A. Vierra, Serena T. Ly, Theron K. Niel, Basma M. Hasan, Daniel E. Crocker, Daniel P. Costa

Pacific Faculty Work

Unlike many animals that reduce activity during fasting, northern elephant seals (NES) undergo prolonged fasting during energyintensive life-history stages such as reproduction and molting, fueling fasting energy needs by mobilizing fat stores accrued during foraging. NES display several unique metabolic features such as high fasting metabolic rates, elevated blood lipid and high-density lipoprotein (HDL) cholesterol levels, efficient protein sparing and resistance to oxidative stress during fasting. However, the cellular mechanisms that regulate these adaptations are still not fully understood. To examine how metabolic coordination is achieved during prolonged fasting, we profiled changes in blubber, skeletal muscle and plasma proteomes of …

The Ability Of Resveratrol To Attenuate Ovalbumin-Mediated Allergic Asthma Is Associated With Changes In Microbiota Involving The Gut-Lung Axis, Enhanced Barrier Function And Decreased Inflammation In The Lungs, Prakash Nagarkatti, Esraah Alharris, Hasan Alghetaa, Juhua Zhou, Mitzi Nagarkatti

Faculty Publications

Asthma is a chronic respiratory disease highly prevalent worldwide. Recent studies have suggested a role for microbiome-associated gut–lung axis in asthma development. In the current study, we investigated if Resveratrol (RES), a plant-based polyphenol, can attenuate ovalbumin (OVA)-induced murine allergic asthma, and if so, the role of microbiome in the gut–lung axis in this process. We found that RES attenuated allergic asthma with significant improvements in pulmonary functions in OVA-exposed mice when tested using plethysmography for frequency (F), mean volume (MV), specific airway resistance (sRaw), and delay time(dT). RES treatment also suppressed inflammatory cytokines in the lungs. RES modulated lung …

Activation Of Ras/Mapk Pathway Confers Mcl-1 Mediated Acquired Resistance To Bcl-2 Inhibitor Venetoclax In Acute Myeloid Leukemia, Qi Zhang, Bridget Riley-Gillis, Lina Han, Yannan Jia, Alessia Lodi, Haijiao Zhang, Saravanan Ganesan, Rongqing Pan, Sergej N Konoplev, Shannon R Sweeney, Jeremy A Ryan, Yulia Jitkova, Kenneth Dunner, Shaun E Grosskurth, Priyanka Vijay, Sujana Ghosh, Charles Lu, Wencai Ma, Stephen Kurtz, Vivian R Ruvolo, Helen Ma, Connie C Weng, Cassandra L Ramage, Natalia Baran, Ce Shi, Tianyu Cai, Richard Eric Davis, Venkata L Battula, Yingchang Mi, Jing Wang, Courtney D Dinardo, Michael Andreeff, Jeffery W Tyner, Aaron Schimmer, Anthony Letai, Rose Ann Padua, Carlos E Bueso-Ramos, Stefano Tiziani, Joel Leverson, Relja Popovic, Marina Konopleva

Faculty, Staff and Student Publications

Despite high initial response rates, acute myeloid leukemia (AML) treated with the BCL-2-selective inhibitor venetoclax (VEN) alone or in combinations commonly acquires resistance. We performed gene/protein expression, metabolomic and methylation analyses of isogenic AML cell lines sensitive or resistant to VEN, and identified the activation of RAS/MAPK pathway, leading to increased stability and higher levels of MCL-1 protein, as a major acquired mechanism of VEN resistance. MCL-1 sustained survival and maintained mitochondrial respiration in VEN-RE cells, which had impaired electron transport chain (ETC) complex II activity, and MCL-1 silencing or pharmacologic inhibition restored VEN sensitivity. In support of the importance …

Mitoprotective Effects Of A Synergistic Nutraceutical Combination: Basis For A Prevention Strategy Against Alzheimer’S Disease, Dona P.W. Jayatunga, Eugene Hone, Binosha W.M.A. Fernando, Manohar L. Garg, Giuseppe Verdile, Ralph N. Martins

Research outputs 2022 to 2026

Evidence to date suggests the consumption of food rich in bioactive compounds, such as polyphenols, flavonoids, omega-3 fatty acids may potentially minimize age-related cognitive decline. For neurodegenerative diseases, such as Alzheimer’s disease (AD), which do not yet have definitive treatments, the focus has shifted toward using alternative approaches, including prevention strategies rather than disease reversal. In this aspect, certain nutraceuticals have become promising compounds due to their neuroprotective properties. Moreover, the multifaceted AD pathophysiology encourages the use of multiple bioactive components that may be synergistic in their protective roles when combined. The objective of the present study was to determine …

A Retrospective Investigation: Outcome Comparisons Between Septic Patients With And Without Secondary Diagnosis Of Hypothyroidism From A Rural Midwest Hospital, Anna Eshghi, Aaron S. Fanaee, Shelly N.B. Sloan, Greg Stahl, Kerry Johnson, Scott Goade, Robert Arnce

Faculty and Staff Publications

Background

Sepsis morbidity and mortality rates have remained high despite recent developments in clinical guidelines aimed to curtail this disease process. Understanding how sepsis interacts with comorbidities and pre-existing disease states is necessary for improving sepsis treatment. Accounting for specific pre-existing conditions in the treatment of sepsis patients may not only improve patient outcomes but also reduce healthcare costs by preventing possible complications. We sought to evaluate whether the presence of hypothyroidism affects outcomes in septic patients.

Methods

In this retrospective observational study, we analyzed the patient dataset from a not-for-profit rural hospital from January 2019 through June 2020. We …

Transitions Of Care: Completeness Of The Interoperability Data Standard For Communication From Home Health Care To Primary Care., Edgar Chou, Paulina S Sockolow

Department of Medicine Faculty Papers

Data sharing is necessary to address communication deficits along the transitions of care among community settings. Evidence-based practice supports home healthcare (HHC) patients to see their primary care team within the first two weeks of hospital discharge to reduce rehospitalization risk. A small subset of patient data collected at HHC admission is mandated to be transmitted to primary care, predominantly by fax. Using qualitative analysis, we assessed completeness of the United States Core Data for Interoperability (USCDI) interoperability standard, as compared to the patient data collected by the primary care team (topics) and HHC (classes) during the initial visit; and …

Associations Between Potential Inflammatory Properties Of The Diet And Frequency, Duration, And Severity Of Migraine Headaches: A Cross-Sectional Study, Seyed Mojtaba Ghoreishy, Gholamreza Askari, Hamed Mohammadi, Marilyn S. Campbell, Fariborz Khorvash, Arman Arab

Kinesiology and Health Promotion Faculty Publications

Despite a large body of literature on the association between the dietary inflammatory index (DII) and various chronic diseases, limited knowledge is available regarding the association between DII and migraine. Therefore, we assessed the relationship between the DII and migraine characteristics, including duration, frequency, and severity of migraine headaches, Headache Impact Test-6 (HIT-6), and serum levels of nitric oxide (NO). This population-based cross-sectional study was conducted from August 2019 to June 2020 among 262 patients (38 men and 224 women; 20-50 years). A 168-item semiquantitative food frequency questionnaire (FFQ) was gathered to evaluate dietary intake, and subsequently, an energy-adjusted DII …

The Influence Of Preoperative Dialysis On Survival After Continuous-Flow Left Ventricular Assist Device Implantation, Harveen K Lamba, Fadi I Musfee, Subhasis Chatterjee, Ajith P Nair, Andrew B Civitello, Leo Simpson, O H Frazier, George V Letsou

Faculty, Staff and Students Publications

OBJECTIVES: Dialysis is considered a contraindication to continuous-flow left ventricular assist device (CF-LVAD) implantation. We evaluated clinical outcomes and survival in carefully selected, low-risk patients with renal failure who required dialysis before CF-LVAD implantation.

METHODS: We extracted medical record data of patients who underwent CF-LVAD placement at our centre between 1 January 2006 and 31 August 2017, with 2 clinical scenarios: those who required long-term (>14 days) dialysis and those who required short-term (≤14 days) dialysis immediately before implantation. Demographic, clinical and intraoperative characteristics and survival outcomes were assessed.

RESULTS: Of 621 patients who underwent CF-LVAD implantation during the …

From Stigma To Treatment: The Hiv/Aids Epidemic And The Opioid Epidemic, Nicole Blanchard

University of Memphis Law Review

No abstract provided.

Diet Quality Scores And Cardiometabolic Risk Factors In Mexican Children And Adolescents: A Longitudinal Analysis, Abeer Ali Aljahdali, Karen E. Peterson, Alejandra Cantoral, Edward Ruiz-Narvaez, Martha M. Tellez-Rojo, Hyungjin Myra Kim, James R. Hébert Scd, Michael David Wirth Msph, Phd, Face, Libni A. Torres-Olascoaga, Nitin Shivappa Mbbs, Mph, Ph.D., Ana Baylin

Faculty Publications

There is limited evidence for the effects of diet on cardiometabolic profiles during the pubertal transition. We collected repeated measures of diet quality and cardiometabolic risk factors among Mexican youth. This analysis included 574 offspring of the Early Life Exposure in Mexico to Environmental Toxicants (ELEMENT) birth cohort followed up to three time points. Dietary Approaches to Stop Hypertension (DASH), alternate Mediterranean Diet (aMedDiet), and Children’s Dietary Inflammatory Index (C-DII^TM) scores were computed from food frequency questionnaires. Higher DASH and aMedDiet scores reflect a higher diet quality, and lower C-DII scores reflect an anti-inflammatory diet. Cardiometabolic risk factors …

Promoting Development Of Urban-Rural Integration By Urban Agriculture, Qichang Yang

Bulletin of Chinese Academy of Sciences (Chinese Version)

How to solve the widening gap between urban and rural areas caused by the rapid development of urbanization and its siphonic effect has become the focus of the whole society. The unique role of urban agriculture in expanding urban agricultural space, enhancing the elasticity of urban food supply, ensuring residents' physical and mental health, improving the ecological environment, and reducing carbon footprint was discussed, from the perspectives of urban agriculture's connotation and denotation, morphological characteristics and functions. Besides, the potential role of urban agriculture in solving the issues of rural and urban development and the method and strategies of integration …

The Role Of Economics And Culture In Determining Fertility Rates In Kenya, Randall Rogers

Great Plains Sociologist

The role of both economic and cultural factors are investigated for their impact on fertility rates in Kenya. Economic factors tend to favor rational control of fertility while cultural factors favor uncontrolled fertility. Both demand and supply side reasons are presented to show that fertility decision making is becoming based more on economics and rationality than on tradition. Policy implications are investigated.

Book Reviews

Great Plains Sociologist

Diane Kayongo-Male, reviewer
Gendered Fields: Rural Women, Agriculture, and Environment
Carolyn Sachs

Henry B. Sirgo, reviewer
Green Culture: Environmental Rhetoric in Contemporary America
Carl G. Herndl and Stuart C. Brown

Janet Kelly Moen, reviewer
New Government for Rural America: Creating Intergovernmental Partnerships
Beryl A. Radin, Robert Aganoff, Ann O'M Bowman, C. Gregory Buntz, Steven Ott, Barbara S. Romzek, and Robert H. Wilson

Jon Flanagin, reviewer
Wanted Dead or Alive: The American Westin Popular Culture
Richard Aquila, editor

Laura Colmenero, reviewer
Contented Among Strangers: Rural German-Speaking Women and Their Families in the Nineteenth-Century Midwest
Linda Schelbitzki Pickle

Elizabeth Evenson Williams, reviewer …

Infant Mortality On Northern Plains Reservations, Linda Neuerburg, Janet Kelly Moen

Great Plains Sociologist

The infant mortality among Indian people living on the Northern Plains reservations (18.4per 1,000) is nearly double that of the U.S. infant mortality rate (9.8per 1,000). Data were collected for 19 reservations through the Healthy Start Program established to combat this problem, using the reservation as the unit of analysis. Relationships were hypothesized between reservations with high infant mortality rates and high alcohol consumption, tobacco use, poverty levels, and low availability of certain social services. The analysis substantiated only one major variable—poverty. Further analysis suggested that mortality rates were higher on reservations that did not provide social support programs such …

Rare Coding Variants In Rcn3 Are Associated With Blood Pressure, Karen Y. He, Tanika N. Kelly, Heming Wang, Jingjing Liang, Luke Zhu, Brian E. Cade, Themistocles L. Assimes, Lewis C. Becker, Amber L. Beitelshees, Lawrence F. Bielak, Adam P. Bress, Jennifer A. Brody, Yen-Pei Christy Chang, Yi-Cheng Chang, Paul S. De Vries, Ravindranath Duggirala, Ervin R. Fox, Nora Franceschini, Anna L. Furniss, Yan Gao, Donna K. Arnett

Epidemiology and Environmental Health Faculty Publications

BACKGROUND: While large genome-wide association studies have identified nearly one thousand loci associated with variation in blood pressure, rare variant identification is still a challenge. In family-based cohorts, genome-wide linkage scans have been successful in identifying rare genetic variants for blood pressure. This study aims to identify low frequency and rare genetic variants within previously reported linkage regions on chromosomes 1 and 19 in African American families from the Trans-Omics for Precision Medicine (TOPMed) program. Genetic association analyses weighted by linkage evidence were completed with whole genome sequencing data within and across TOPMed ancestral groups consisting of 60,388 individuals of …

Patients With Obesity And A History Of Metformin Treatment Have Lower Influenza Mortality: A Retrospective Cohort Study, Tammy H. Cummings, Joseph Magagnoli Ph.D., Ms, James W. Hardin, S. Scott Sutton

Faculty Publications

Background: Obesity is a risk factor for the development of influenza by leading to a chronic inflammatory state and T-cell dysfunction. Based upon preclinical research, metformin has influenza activity by restoring T-cell function and improving the immune response. Objective: We aimed to evaluate the potential drug repurposing of metformin for the management of influenza among patients with obesity utilizing national claims data in an electronic health record database. Methods: The VA Informatics and Computing Infrastructure (VINCI) was utilized to obtain individual-level information on demographics, administrative claims, and pharmacy dispensation. A cohort was created among individuals with laboratory confirmed diagnosis of …

The Role Of Improved Forages In Solving The Water Scarcity Issue Of 4 Billion People, S. Douxchamps, A. Notenbaert, J. A. Cardoso, M. Romero, M. Peters

IGC Proceedings (1977-2023)

Global animal production requires about 2422 Gm³ of water per year. Most of this volume is used by cattle, with 30% used in the beef sector and another 19% in the dairy sector. At the same time, four billion people suffer from severe water scarcity, raising the flag on diverting an important part of the water globally to livestock production. Livestock-water interactions have therefore gained a prominent profile and fuelled discussions on the water footprint of livestock. A series of studies on the most important components of the livestock water footprint have shown that globally more than 90% of …

Species Richness Increased Yield Stability In Intensively Managed Grasslands Subjected To Experimental Drought, J. A. Finn, M. Suter, E. Haughey, D. Hofer, A. Lüscher

IGC Proceedings (1977-2023)

Climate change is expected to cause an increase in the frequency and intensity of drought events. Over two years we investigated the effects of experimentally imposed drought on intensively managed grassland communities (5 m x 6 m plots) of varying richness (1, 2 and 4 species), and comprising four species (Lolium perenne L., Cichorium intybus L., Trifolium repens L., Trifolium pratense L.). In each year a summer drought period of nine weeks with complete exclusion of precipitation was simulated, inducing severe drought stress at Reckenholz (Zürich, Switzerland), and extreme drought stress at Wexford (Ireland). Mean yield and plot-to-plot variance …

Slis Connecting, Volume 10, Issue 2 Fall/Winter, Stacy Creel, Ph.D.

SLIS Connecting

SLIS Connecting -- the whole issue with all three Columns, one editorial, one professional article, and seven research articles.

Poster Presentation, Sarah Williams, Stacy Creel, Ph.D.

SLIS Connecting

Posters are an important part of scholarly and professional communication. In an effort to encourage students at the School of Library & Information Science to be active participants in these types of events, students may participate in an optional student symposium, but they are required to create research posters in their capstone LIS 695. These are helpful resources and recent examples.

A Facial Congenital Anomaly In A Mature Male White-Tailed Deer (Odocoileus Virginianus), Travis Cunningham, Al Mead

Georgia Journal of Science

Congenital anomalies are rarely documented in wild ungulates. This study describes a congenital facial malformation in a mature male white-tailed deer harvested in central Georgia in 2020. The skull displays a mediolateral deflection of the rostrum, and the mandibles display similar deflection with posterior rotation at the mandibular symphysis, a maxillofacial malformation commonly called wry face. Based on physical examination and radiographic imagery, there were no signs of neoplasia or healed bone trauma on the skull or jaws, suggesting a congenital origin for the deformity. Studies of domestic horses displaying wry face conclude that the malformation arises from fetal mispositioning …

Book Reviews

Great Plains Sociologist

Geoffrey Grant
The Poverty Debate: Politics and the Poor in America
C. Emory Burton

Stewart E. Kelly
Beyond Individualism
Jack Crittenden

Thomas C. Langham
Rural Communities: Legacy and Change
Cornelia Butler Flora, Jan L. Flora, Jacqueline D. Spears, and Louis E. Swanson

Patricia Ann Wasely Lomire
Next of Kin: An International Reader on Changing Families
Lorne Tepperman and Susannah J. Wilson (eds.)

B. Diane Miller
The Human Difference: Animals, Computers, and the Necessity of Social Science
Alan Wolfe

Janet Kelly Moen
The Cultures of Work Organizations
Harrison M. Trice and Janice M. Beyer

George Nielson
Emergent Issues in Education: Comparative …