Digital Commons Network^™

The Who Global Tuberculosis 2021 Report - Not So Good News And Turning The Tide Back To End Tb, Chakaya Jeremiah, Eskild Petersen, Rebecca Nantanda, Brenda N. Mungai, Giovanni Battista Migliori, Farhana Amanullah, Patrick Lungu, Francine Ntoumi, Nagalingeswaran Kumarasamy

Department of Paediatrics and Child Health

Objective: To review the data presented in the 2021 WHO global TB report and discuss the current constraints in the global response.
Introduction and methods: The WHO global TB reports, consolidate TB data from countries and provide up to date assessment of the global TB epidemic. We reviewed the data presented in the 2021 report.
Results: We noted that the 2021 WHO global TB report presents a rather grim picture on the trajectory of the global epidemic of TB including a stagnation in the annual decline in TB incidence, a decline in TB notifications and an increase in estimated TB …

Book Review Of The Law Student’S Guide To Doing Well And Being Well, Lawrence Krieger

Journal of Legal Education

No abstract provided.

Prevention Of Central Line-Associated Blood Stream Infection (Clabsi) In Adult Icu Patients, Salima Allahbachayo

Student Scholarly Projects

Practice Problem: Central line-associated bloodstream infections (CLABSI) account for most hospital-associated preventable infections in the United States and globally. Implementation of a multifaceted approach including evidence-based CLABSI bundle care has shown to prevent this infection in patients with a central line.

PICOT: The PICOT question that guided this project was that in adult intensive care unit (ICU) patients, how does the use of central line bundle care compared to central line care without bundle decrease central line-associated bloodstream infections within eight weeks?

Evidence: The evidence from a rigorous literature review showed that using a central line bundle …

Association Between Serum Lycopene And Lung Cancer Mortality: An 18-Year Follow-Up Study Of A National Cohort, Evans Afriyie-Gyawu, Padmini Shankar, Gulzar H. Shah, Alicia A. Brown, Shannon Cearley, Akwasi Ampofo-Yeboah, Nathaniel Abrams, Jian Zhang

Health Policy & Community Health: Faculty Publications

Background: Lycopene is a carotenoid found in some fruits and vegetables that is responsible for the red pigment in tomatoes and tomato products. While many studies have shown a link between lycopene and protection against the initiation and/or progression of lung cancer, data on its effect on lung cancer survivability is limited.

Objective: The primary objective of this study was to see if there was a link between lycopene levels in the blood and lung cancer mortality. A secondary goal was to see if dietary factors influence lycopene levels in the blood.

Materials and Methods: A retrospective …

A Mixed-Methods Study To Determine The Impact Of Covid-19 On Food Security, Food Access And Supply In Regional Australia For Consumers And Food Supply Stakeholders, Stephanie Louise Godrich, Johnny Lo, Katherine Kent, Flavio Macau, Amanda Devine

Research outputs 2022 to 2026

Background: The COVID-19 pandemic has impacted the Australian food supply through changed consumer purchasing patterns, and potentially, household food security. The aim of this study was to determine the impact of COVID-19 on the prevalence of food insecurity and food supply issues, and perspectives of food supply stakeholders in regional Australia. Methods: A mixed-methods consumer survey and in-depth interviews with food supply stakeholders were conducted in regional Australia, more specifically South West Western Australia between May and July 2020, immediately after the 1st wave of the pandemic. Results: The prevalence of food insecurity was 21% among consumers, and significantly more …

Prevalence Of Non-Alcoholic Fatty Liver Disease, Clinical And Laboratory Markers, Abror А. Хamrayev, Dilnavoz X. Yuldasheva

Central Asian Journal of Medicine

Aim of the research. To determine the clinical and laboratory features of non-alcoholic fatty liver disease at the stage of fatty hepatosis and steatohepatitis. Materials and methods. To solve the set tasks, 98 patients with non-alcoholic fatty liver disease (NAFLD) were examined, including 67 (68.3%) patients at the stage of hepatic steatosis (HS) and 31 (31.6%) patients with steatohepatitis (SH). Of these, 45 (46%) men and 53 (54%) women aged 20 to 75 years (average age 49.2 ± 4.2). Results. With steatohepatitis, higher ALT and AST values are noted than in patients with hepatic steatosis. The article contains clinical features …

Evaluation Of The Nutritional Status Of Patients With Chronic Liver Diseases And Their Dietary Correction, Sherzod Y. Zokirkhodjaev, Malika K. Pattakhova, Mirilkhom U. Solikhov, Sardor B. Mutalov

Central Asian Journal of Medicine

Improving the organization and increasing the efficiency of clinical nutrition in the complex management of patients with various diseases is one of the most important problems of modern medicine. Chronic hepatitis is one of the most prevalent illness among liver diseases. The social significance of chronic hepatitis is determined by the fact that they can progress to liver cirrhosis and hepatocellular carcinoma, which are characterized by a high level of disability and mortality. Very little attention has been paid to factors associated with nutritional status which are abnormal in a significant number of patients with chronic hepatitis. The purpose of …

Role Of Aggressive-Protective Factors In Lesions Of The Gastroduodenal Zone In Adolescents, Nargiza Salimova, Muborak Salaeva, Lola Abduraximova

Central Asian Journal of Medicine

The high frequency of pathology of the digestive system in children, adolescents and adults, the absence of a tendency to decrease it remains one of the urgent problems of internal medicine. The aim of this study was to study the role of aggressive and protective factors in the occurrence of gastric ulcer and duodenal ulcer in adolescents. The objective of the study. The study of the peculiarities of the relationship between aggressive and protective factors in the mucous membrane of the gastroduodenal zone with its various lesions in adolescents. Material and methods. Clinical studies were carried out in the City …

Pharmacologic Ascorbic Acid As Early Therapy For Hospitalized Patients With Covid-19: A Randomized Clinical Trial, Dagan Coppock, Pierre-Christian Violet, Gustavo Vasquez, Katherine Belden, Michael Foster, Bret Mullin, Devon Magee, Isabelle Mikell, Lokesh Shah, Victoria Powers, Brian Curcio, Daniel A. Monti, Mark Levine

Department of Pharmacology and Experimental Therapeutics Faculty Papers

Despite the widespread availability of effective vaccines, new cases of infection with severe acute respiratory syndrome coronavirus-2, the cause of coronavirus disease 2019 (COVID-19), remain a concern in the settings of vaccine hesitancy and vaccine breakthrough. In this randomized, controlled, phase 2 trial, we hypothesized that high-dose ascorbic acid delivered intravenously to achieve pharmacologic concentrations may target the high viral phase of COVID-19 and thus improve early clinical outcomes. Sixty-six patients admitted with COVID-19 and requiring supplemental oxygen were randomized to receive either escalating doses of intravenous ascorbic acid plus standard of care or standard of care alone. The demographic …

What Will And Won’T Happen When Abortion Is Banned, Michelle Oberman

Faculty Publications

For the past fifty years, abortion opponents have fought for the power to ban abortion without little attention to how things might change when they won. The battle to make abortion illegal has been predicated on three nebulous assumptions about how abortion bans work. First, supporters believe banning abortion will deter it. Second, they hope bans will send a message about abortion—specifically, that abortion is immoral. And third, they expect bans to be competently implemented and enforced.

Drawing on empirical work from within and outside of the U.S., this Article offers an evidence-based assessment of each of these assumptions. Part …

Television Viewing Time And All-Cause Mortality: Interactions With Bmi, Physical Activity, Smoking, And Dietary Factors, Christopher T. Swain, Julie K. Bassett, Allison M. Hodge, David W. Dunstan, Neville Owen, Yi Yang, Harindra Jayasekara, James R. Hébert Scd, Nitin Shivappa Mbbs, Mph, Ph.D., Robert J. Macinnis, Roger L. Milne, Dallas R. English, Brigid M. Lynch

Faculty Publications

Background Higher levels of time spent sitting (sedentary behavior) contribute to adverse health outcomes, including earlier death. This effect may be modified by other lifestyle factors. We examined the association of television viewing (TV), a common leisure-time sedentary behavior, with all-cause mortality, and whether this is modified by body mass index (BMI), physical activity, smoking, alcohol intake, soft drink consumption, or diet-associated inflammation. Methods Using data from participants in the Melbourne Collaborative Cohort Study, flexible parametric survival models assessed the time-dependent association of self-reported TV time (three categories: < 2 h/day, 2-3 h/day, > 3 h/day) with all-cause mortality. Interaction terms were fitted to test whether …

68-Year Old Man With Progressive Weakness And Ventilator Dependent Respiratory Failure: A Case Report Of Sporadic Late Onset Nemaline Myopathy, P. Kirupaharan, Daniel Kramer, Alan Gandler, Lawrence C. Kenyon, Ross Summer

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Background: Neuromuscular pathologies must be considered when caring for patients with persistent or progressive respiratory failure. Pertinent disease states may involve skeletal muscles of respiration or associated neurologic structures including motor neurons, peripheral neurons and the neuromuscular junction. Diagnosis may require pulmonary function testing, neurophysiologic studies, imaging, and/or muscle biopsy.

Case presentation: A 68-year-old male was transferred to our intensive care unit (ICU) for management of ventilator dependent respiratory failure. Upon further historical review, he described gradually worsening gait instability and muscle weakness, which was previously attributed to vascular Parkinsonism in the setting of known cerebrovascular disease. Upon arrival to …

Polyketides And Terpenes In Marine Microalgae: Ecological Roles And Mechanisms Of Biosynthesis, Yunxuan Xie, Mohammad Elsheikh

Journal of Marine Science and Technology–Taiwan

Marine microalgae comprise a large number of polyketides and terpenes identified to date with highly diverse molecular scaffolds and the biological activities (Kalaitzis et al., 2010). These compounds play significant roles in marine food web and nutraceutical supplementation in marine animals. Compounds of this class are often synthesized by gene clusters with dedicated domains responsible for carbon chain extension and modification. The unique molecular structure of these compounds encourages people to investigate their biosynthetic mechanisms in-depth. In this review, we summarize relevant articles to unravel the shared mechanisms of these compounds to further understand the variety of domain organizations and …

Effects Of Dietary Lipid, L-Carnitine And L-Lysine Supplementation On The Growth Performance And Body Composition Of Epinephelus Lanceolatus Larvae, Jen-Hong Chu, Yu-Cong Hong, Angela Chien, Shyn-Shin Sheen

Journal of Marine Science and Technology–Taiwan

The effects of different combinations of dietary lipid, L-carnitine and L-lysine on the growth performance and fatty acid profiles of larval grouper Epinephalus lanceolatus were evaluated. Eight treatment diets were formulated based on a 2x2x2 factorial design, namely 5 and 14% dietary oil mixture (3:1 fish oil/soybean oil), 0 and 0.5% L-carnitine and 0 and 2.83% L-lysine. Each diet was randomly assigned to triplicate groups of ten 0.08g E. lanceolatus larvae for 42 days. The grouper larvae fed with diets containing 14% lipid had significantly higher weight gain percentages than those fed with diets containing 5% lipid. The weight gain …

Having Children And Physical Activity Level And Other Types Of Pro-Health Behaviour Of Women From The Perspective Of The Theory Of Planned Behaviour, Piotr Wlodarczyk, Artur Ziolkowski

Baltic Journal of Health and Physical Activity

Background: The subject of the paper is pro-health behaviour of women (N=477) who have children (N=124) and those who have no children (N=353). The Theory of Planned Behaviour (TPB) by Icek Ajzen, in the light of which the differences in the health behaviour level of the sample group are considered, constitutes the theoretical basis of this work. Material/Methods: The research group consisted of women at the age of 19–36 (M=27,5 yrs of age SD=4 yrs of age). The Health and Behaviour Survey Questionnaire by Steptoe and Wardle was used for the measurement. Four scales of healthy behaviour values, i.e., taking …

Different Forms Of Swimmers’ Final Weeks Pre-Competition Preparation, Kamil Sokolowski, Marek Strzala, Arkadiusz Stanula

Baltic Journal of Health and Physical Activity

The pre-competition training phase is a period that precedes the main competition. Combined training phases of overload training (OT) and taper (TP) create the most popular pattern of final form preparation among the swimmers despite the methodology difficulties faced by coaches. In the IPC, the duration and training load were strictly set. The main purpose of training in the IPC is to cause a substantial supercompensation effect by the high volume and capacity of the training. However, high volume and intensity fluctuations typical of the IPC may cause performance regression due to overtraining and exhaustion. The main aim of the …

Exercise − A Unique Endogenous Regulator Of Irisin, Bdnf, Leptin And Cortisol Against Depression, Gilmara Gomes De Assis, Pawel Cieszczyk

Baltic Journal of Health and Physical Activity

Depression is the most prevalent stress-related disorder affecting the population world-wide with potential for an eminent increase after the 2020 pandemic. The mechanisms through which metabolism is involved in depression and stress disorders have been extensively investigated. However, their assessment using exogenous measures is a current limitation. Exercise, as is well reported in animal studies, exerts a critical regulatory influence on the main factors known to participate in these mechanisms. This overview describes the role of cortisol, leptin, irisin and BDNF in the exercise physiology and the known mechanism through which these factors act in anti-depressant mechanisms. Furthermore, the exercise …

Examination Of The Informed Consent Process As Experienced By Patients Who Underwent De Novo Transjugular Intrahepatic Portosystemic Shunt, Chemoembolization Or Radioembolization Procedure, Marsha A. Hughes-Gay

Dissertations

The purpose of this study is to examine the informed consent (IC) procedure as it was experienced by patients who had undergone a de novo transjugular intrahepatic portosystemic shunt (TIPS), chemoembolization (TACE), or radioembolization (TARE) procedure in an Interventional Radiology (IR) Department. The three main study aims and a fourth exploratory aim are as follows: (1) Describe how patients who underwent a de novo TIPS, TACE, or TARE procedure in an IR Department described the IC procedure; (2) Describe what information patients who underwent a de novo TIPS, TACE, or TARE procedure in an IR Department recalled being told during …

Faculty Member Wins Regional Honor For Advising Excellence, Cameron Smith

University of Mississippi News

Georgianna Mann lauded for pushing students to excel beyond comfort zones

Food Consumption Frequency, Perceived Stress, And Depressive Symptoms Among Female University Students In Dubai, United Arab Emirates, Ohoud Mohamad, Haleama Al Sabbah, Linda Smail, Ehab W. Hermena, Rola Al Ghali

All Works

This study assessed whether perceived stress and depressive symptoms were associated with the frequency of consumption of specific food groups among female university students. A cross-sectional study was conducted among female university students using a simple random sampling method. The response rate was 97%, with a total number of 385 participants. The associations between stress levels and most/least-consumed food groups, and between depressive symptoms levels and most/least-consumed food groups were assessed. The questionnaire included a 12-item self-administered food frequency questionnaire, Cohen's Perceived Stress Scale, and the Beck Depression Inventory-II. The study was approved by the University Ethical Committee prior to …

Is The Biggest Offer The Best Offer?, Alyssa Croft

Pace Intellectual Property, Sports & Entertainment Law Forum

Many people strive to be professional athletes because of the respect and accomplishment it receives. You make a lot of money, it can be glamorous, you are in commercials and magazines, and sometimes even movies. However, there are some things people do not think about when it comes to professional athletes. One of the biggest is taxation! There are so many different things athletes must think about and do because of taxes so they can take home the most amount of money possible. Athletes must be careful about who they hire to help them with their taxes because they want …

The Large And Small Of It: The Microbiome And Metagenomics, Austin Hopkins, Elaina Gollmar, Jessica Fernandez, Shawn Wolf, Austin Hilverding, Andrew M. Roecker

Pharmacy and Wellness Review

Metagenomics, the analysis of the microbial genome, permits scientists to understand the influences of external sources including diet, metabolism and antibiotics on the human microbiome. Research has revealed the possibility of a core symbiosis between humans and bacteria. The main role of the human microbiome is to aid in digestion, but identified ancillary roles include immunologic homeostasis and infection prevention. Quantifying the composition and variability of the microbiome will help lead to future treatments or preventive strategies against unhealthy change. A variety of methods may be used to define the microbiome, and 16S amplicon sequencing is primarily utilized today. Probiotics …

Management Of Hyperkalemia To Prevent Cardiac Arrest, Jennifer Harklerode, Amber Paul, Crystal Zheng, Olivia Vanscoy, Olivia Henton, Mark Olah

Pharmacy and Wellness Review

Hyperkalemia is a metabolic problem that may be life threatening if left untreated. Cardiac arrhythmias may develop with the potential to lead to cardiac arrest and death. Hyperkalemia can oftentimes be undiagnosed due to the lack of clear, specific symptoms and inconclusive variations in electrocardiogram (ECG) readings and lab values. Therefore, it is important to recognize risk factors that can potentially in-crease serum potassium levels. Screening for medications that increase serum potassium levels and educating patients are steps that both inpatient and outpatient health care professionals can take to increase early detection and prevention of a hyperkalemic episode. It is …

Development And Management Of Depression During And After Pregnancy, Alexa Bouts, Maria Patnella, Jourdan Ujlaki, Emily Wells, Hannah Lamb, Michelle Musser

Pharmacy and Wellness Review

Depression during pregnancy is common, whether it is a new onset of the disease or emerging symptoms of the already existent disease. Due to patient and prescriber concerns with antidepressant use during pregnancy, approximately three-quarters of those diagnosed with depression remain untreated. Furthermore, up to half of pregnant women with depression remain undiagnosed due to lack of recognition. As a result, both mother and fetus are at risk for negative health outcomes including substance abuse, functional impairment, increased risk of postnatal depression and poor pregnancy outcomes. Benefits must be balanced against the risks when considering pharmacologic treatment options to manage …

Vol.49 N.35 March 17th 2022, Voice Media Ventures

Black Voice News

No abstract provided.

Kassem Hafeed V. Attorney General United States

2022 Decisions

Agency

Queueing Theory Model Of Pentose Phosphate Pathway, Sylwester M. Kloska, Krzysztof Pałczyński, Tomasz Marciniak, Tomasz Talaśka, Marissa Miller, Beata J. Wysocki, Paul H. Davis, Tadeusz A. Wysocki

Department of Electrical and Computer Engineering: Faculty Publications

Due to its role in maintaining the proper functioning of the cell, the pentose phosphate pathway (PPP) is one of the most important metabolic pathways. It is responsible for regulating the concentration of simple sugars and provides precursors for the synthesis of amino acids and nucleotides. In addition, it plays a critical role in maintaining an adequate level of NADPH, which is necessary for the cell to fight oxidative stress. These reasons prompted the authors to develop a computational model, based on queueing theory, capable of simulating changes in PPP metabolites’ concentrations. The model has been validated with empirical data …

Tackling Protein-Calorie Malnutrition During World Crises, Zahra Ali Padhani, Jai K. Das, Saeed Akhtar, Tariq Ismail, Zulfiqar Ahmed Bhutta

Woman and Child Health

Undernutrition is still highly prevalent in developing countries and leads to a multitude of problems as it weakens the immune system, which leads to increased risk of infections and diet-related diseases. COVID-19 has worsened the existing situation and has resulted in unprecedented health, social, and economic disruptions across the world. Before COVID-19, about 54% children under 5 years were moderately or seriously malnourished, and after the COVID-19 pandemic, early estimates suggest that an additional 2.6 million children were stunted; 9.3 million were wasted, with an addition of 2.1 million maternal anemia cases; 168,000 child deaths; and USD 29.7 billion in …

Behavioral And Physiological Effects Of Heavy Metals On Fish: A Review And Preliminary Results, Diana V. Morales

Theses and Dissertations

Pollution, specifically heavy metal pollution, in various bodies of water has been a significant issue for decades. Research has been conducted on heavy metals and their effects on the environment, larger fish species, and humans since the 1970s (Skidmore, 1964; Adeniyi et al., 2007; Adeosun et al., 2015; Bawuro et al., 2018). It is known that zinc is a neurotoxin in some species and causes harm to the environment. It is also known that it causes harm to people if it is ingested or if they are exposed to it for long periods of time (Mahurpawar, 2015; Mizuno and Kawahara, …

Intervention Effects Of A Cognitive Behavioral Skills Building Program On Newly Licensed Registered Nurses, Marlene Sampson

Dissertations

The well-being of healthcare clinicians is considered a national crisis. Healthcare clinicians, including nurses, have higher rates of substance abuse, depression and suicide than the national average. Depression and poor health in nurses are linked to medical errors and patient dissatisfaction. Ninety-one percent of NLRNs report high stress levels resulting in stress-related illness, absenteeism and burnout. In 2017, the National Academy of Medicine launched the Action Collaborative on Clinician Well-being to develop evidence-based solutions to reduce this public health epidemic. The purpose of this study was to examine the effects of a Cognitive Behavioral Therapy (CBT)-based skills building program entitled …