Digital Commons Network^™

The Role Of Natural Products And Their Multitargeted Approach To Treat Solid Cancer, Naoshad Muhammad, Darksha Usmani, Mohammad Tarique, Huma Naz, Mohammad Ashraf, Ramesh Raliya, Shams Tabrez, Torki A Zughaibi, Ahdab Alsaieedi, Israa J Hakeem, Mohd Suhail

2020-Current year OA Pubs

Natural products play a critical role in the discovery and development of numerous drugs for the treatment of various types of cancer. These phytochemicals have demonstrated anti-carcinogenic properties by interfering with the initiation, development, and progression of cancer through altering various mechanisms such as cellular proliferation, differentiation, apoptosis, angiogenesis, and metastasis. Treating multifactorial diseases, such as cancer with agents targeting a single target, might lead to limited success and, in many cases, unsatisfactory outcomes. Various epidemiological studies have shown that the steady consumption of fruits and vegetables is intensely associated with a reduced risk of cancer. Since ancient period, plants, …

A Case Report Of Non-Surgical Esophagocutaneous Fistula Closure: Even A Blind Squirrel Finds A Nut, Emily Zurbuchen

Graduate Medical Education Research Journal

No abstract provided.

No Rest, All Play: A Case Of Pediatric Foot Pain, Connor Wagner

Graduate Medical Education Research Journal

No abstract provided.

Successful Treatment Of Radiation-Induced Colitis And Enteritis With Hyperbaric Oxygen Therapy, Mark D. Ringle, Jeffrey S. Cooper

Graduate Medical Education Research Journal

Introduction

Previously irradiated tissue is characterized by changes including decreased vascularity, impaired cellular proliferation, and local hypoxia consistent with fibroblastic atrophy which can persist long after radiation therapy. Hyperbaric oxygen therapy has been shown to be beneficial in the treatment of complications arising from these late effects of radiation on normal tissue through enhancing fibroblast proliferation, collagen maturation, stem cell recruitment, and angiogenesis.

Methods

We report on three patients with debilitating radiation enterocolitis causing issues including recurrent bowel obstruction, anorexia requiring total parenteral nutrition, pain, diarrhea, fecal incontinence, dehydration, and malnutrition.

Results

In all three cases marked improvement was the …

Leadership And Human Resource Management During Crisis, Ghenwa Al Hakim, Bettina Lynda Bastian, Madonna Salameh Ayanian, Nada Sarkis

Arab Economic and Business Journal

The present paper investigates the role of leadership and human resource management (HRM) in times of crisis. The analysis is situated within the context of Lebanon which is facing the challenges of the COVID-19 pandemic whilst undergoing a devastating economic crisis and downturn. Based on 23 interviews with managers, the paper recognizes attributes of effective leadership in a crisis management approach, as well as the role that the HRM plays in driving employee and organizational performance despite external challenges. In this context, several leadership and HRM practices in response to crisis are identified and discussed.

Vol.49 N.51 July 14th 2022, Voice Media Ventures

Black Voice News

No abstract provided.

The Unique Seed Protein Composition Of Quality Protein Popcorn Promotes Growth Of Beneficial Bacteria From The Human Gut Microbiome, Nate Korth, Leandra Parsons, Mallory J. Van Haute, Qinnan Yang, Preston Hurst, James C. Schnable, David R. Holding, Andrew K. Benson

Food for Health: Publications

The effects of fiber, complex carbohydrates, lipids, and small molecules from food matrices on the human gut microbiome have been increasingly studied. Much less is known about how dietary protein can influence the composition and function of the gut microbial community. Here, we used near-isogenic maize lines of conventional popcorn and quality-protein popcorn (QPP) to study the effects of the opaque-2 mutation and associated quality-protein modifiers on the human gut microbiome. Opaque-2 blocks the synthesis of major maize seed proteins (α-zeins), resulting in a compensatory synthesis of new seed proteins that are nutritionally beneficial with substantially higher levels …

Three Essays On Student Enrollment Responses To General Household And Education-Specific Assistance Programs, Usamah Wasif

Economics ETDs

Greater educational attainment is associated with an increase in expected income, lowering of internal discount rates, and improved financial and health literacy. Income transfers have the potential to positively impact educational attainment by either reducing the direct cost of college attendance or by inducing an income effect that nudges students to decrease labor supply and devote greater time to studies. Whether assistance leads to more education depends on the circumstances, particularly the educational stage and assistance type. High school students may react differently to assistance relative to college students and both may react differently to general household income transfers compared …

Acquisitions Unit Annual Report 2021-2022, Andrée J. Rathemacher

Technical Services Reports and Statistics

Annual Report of the Acquisitions Unit, University Libraries, University of Rhode Island for FY2022. Covers personnel, work flow, special projects, and serial, monograph, and e-resource acquisitions. Supplemental files include data on library materials expenditures by a number of variables as well as important working documents from the year.

Toward A Standard Formal Semantic Representation Of The Model Card Report, Muhammad Tuan Amith, Licong Cui, Degui Zhi, Kirk Roberts, Xiaoqian Jiang, Fang Li, Evan Yu, Cui Tao

Faculty, Staff and Student Publications

BACKGROUND: Model card reports aim to provide informative and transparent description of machine learning models to stakeholders. This report document is of interest to the National Institutes of Health's Bridge2AI initiative to address the FAIR challenges with artificial intelligence-based machine learning models for biomedical research. We present our early undertaking in developing an ontology for capturing the conceptual-level information embedded in model card reports.

RESULTS: Sourcing from existing ontologies and developing the core framework, we generated the Model Card Report Ontology. Our development efforts yielded an OWL2-based artifact that represents and formalizes model card report information. The current release of …

Toward A Standard Formal Semantic Representation Of The Model Card Report, Muhammad Tuan Amith, Licong Cui, Degui Zhi, Kirk Roberts, Xiaoqian Jiang, Fang Li, Evan Yu, Cui Tao

Faculty, Staff and Student Publications

BACKGROUND: Model card reports aim to provide informative and transparent description of machine learning models to stakeholders. This report document is of interest to the National Institutes of Health's Bridge2AI initiative to address the FAIR challenges with artificial intelligence-based machine learning models for biomedical research. We present our early undertaking in developing an ontology for capturing the conceptual-level information embedded in model card reports.

RESULTS: Sourcing from existing ontologies and developing the core framework, we generated the Model Card Report Ontology. Our development efforts yielded an OWL2-based artifact that represents and formalizes model card report information. The current release of …

Applications Of Stretching Technique And Time Window Effects On Ultrasonic Velocity Monitoring In Concrete, Bibo Zhong, Jinying Zhu

Department of Civil and Environmental Engineering: Faculty Publications

Coda wave interferometry (CWI) has been used to measure the relative wave-velocity change (dV/V) caused by small changes in materials. This study uses the stretching processing technique which has been used for CWI analysis to investigate velocity changes of direct longitudinal (P) wave, direct shear (S) wave, and coda wave in concrete by choosing different time windows of ultrasonic signals. It is found that the obtained wave-velocity change depends on the time window position, because the relative contribution of P wave and S wave is different in each signal window. This paper presents three experimental scenarios of velocity …

Pediatric Critical Care Nursing Research Priorities In Asia: An Edelphi Study, Pei Fen Poh, Qian Wen Sng, Jos M. Latour, Linxi He, Mei Fung Fong, M Jayashree, Qalab Abbas, Yujiro Matsuishi, Jan Hau Lee

School of Nursing and Midwifery

No abstract provided.

Developing A Customised Note By Note Prototype Recipe Which Can Be 3d Printed, Roisin Burke, Pauline Danaher

Articles

Note by Note (NbN) cooking and 3D food printing individually and in combination allow for the creation of customized foods. A NbN recipe was developed and printed using a Procusini 3.0, 3D food printer. The recipe was adapted from a commercial powdered pastry dough recipe, to create two versions of a prototype food, containing in each case a different plant-based protein, i.e., soya (Glycine max L.) or hemp (Cannabis sativa). The printed foods were identical in shape and had a crisp consistency following cooking. They had different colours and contained different proteins in the amounts of 10.3 % of soya …

Inflammatory Bowel Disease & Social (In)Visibility: An Interpretive Study Of Food Choice, Self-Blame And Coping In Women Living With Ibd, Jessica N. Lolli

USF Tampa Graduate Theses and Dissertations

This dissertation is an interpretive project that uses autoethnography and qualitative interview methods to understand the role Inflammatory Bowel Disease (IBD) plays in women’s quality of life and interpersonal relationships. It focuses on the impacts on patients of dietary changes and how food choice serves to make this ordinarily “invisible” illness visible to others, leading to unwanted exposure. Using Erving Goffman’s stigma theory and its extensions in studies of chronic illness, I demonstrate that IBD is characterized by layers of stigma because it creates situations in which patients are forced to disclose their illness even if they are not ready …

Taking Responsibility For Systemic Failures: Rhetorical Homologies And Discourses Of Sustainability, Health, And Voting, Alice Grosu

Pepperdine Journal of Communication Research

When considering the discourse of presidential candidates, talk show hosts discussing mental health issues, and companies advertising sustainable goods, this essay argues that they share a formal resemblance. Whenever the same formal resemblance, or the same pattern, can be found within different instances of rhetoric, this indicates that the texts are homologous. Making sense of these instances of discourse is essential if one seeks to understand the way in which the public’s political engagement can be hindered by these rhetorical acts.

High Performance Judoka’S Views On Their Athlete Journey And The Need For Athlete Education, Katrina Mcdonald, Anna Stodter, Mathew Dowling, Justin Roberts

Journal of Athlete Development and Experience

High-performance sport has been the subject of controversy and scandal, coming under heavy scrutiny within the broad issue of “Duty of Care” in terms of the welfare and holistic development of athletes. The United Kingdom has many different schemes and mechanisms that are available to athletes to support them in their development on their athlete journey. However, there is a lack of research exploring whether these schemes and mechanisms fulfill athlete needs and facilitate athlete development. Utilizing Charmaz’s constructivist grounded theory method, twelve full-time, high-performance Judoka (Judo athletes) were intensively interviewed, exploring the experience of their journey as an athlete. …

Leaders Of Tomorrow Make Impact Today, Sustainability Institute

Sustainability Institute Blog

No abstract provided.

Coping Strategies For Inner Conflicts Between Gay Bear Identity And Health Concerns, Chichun Lin, Darren D. Moore

The Qualitative Report

Gay bear refers to a burly gay man with a hirsute body and face. Chinese gay bear men are highly homogeneous and strictly emphasize a uniform bear appearance; however, obesity is an obvious health issue in this population. This study aims to explore the Chinese gay bear men's inner conflicts between bear identity and health concerns. Eleven Chinese gay bear men including four Taiwanese, two mainland Chinese, two Hong Kong, two Malaysian, and one Singaporean were interviewed. The study used a thematic analysis approach and found three coping strategies including (a) Eat healthy but maintain a minimal bear standard; (b) …

Office Of Research, Economic Engagement And Outreach Update, July 13, 2022, Office Of Research, Economic Engagement And Outreach

Office of Research, Economic Engagement and Outreach

No abstract provided.

Association Between State Supplemental Nutrition Assistance Program Policies, Child Protective Services Involvement, And Foster Care In The Us, 2004-2016, Michelle Johnson-Motoyama, Donna K. Ginther, Patricia Oslund, Lindsay Jorgenson, Yoonzie Chung, Rebecca Phillips, Oliver W.J. Beer, Starr Davis, Patricia L. Sattler

School of Health Professions

Importance: Public assistance policies may play a role in preventing child maltreatment by improving household resources among families of low incomes. The Supplemental Nutrition Assistance Program (SNAP) is one of the largest public assistance programs in the US. However, the association of state SNAP policy options to Child Protective Services (CPS) outcomes has not been rigorously examined. Objective: To model the association of state SNAP policies with changes in CPS and foster care outcomes in the US over time. Design, Setting, and Participants: This cohort study used panel data to examine the association between SNAP policy options and study outcomes …

Prevalence Of Health-Risk Behaviors And Mental Well-Being Of Asean University Students In Covid-19 Pandemic, Hanif Abdul Raman, Areekul Amornsriwatanakul, Khadizah H. Abdul-Mumin, Denny Agustiningsih, Surasak Chaiyasong, Michael Chia, Supat Chupradit, Le Quang Huy, Katiya Ivanovitch, Ma. Henrietta Teresa O. De La Cruz

Ateneo School of Medicine and Public Health Publications

The prevalence of epidemiological health-risk behaviors and mental well-being in the COVID-19 pandemic, stratified by sociodemographic factors in Association of South East Asian Nations (ASEAN) university students, were examined in the research. Data were collected in March–June 2021 via an online survey from 15,366 university students from 17 universities in seven ASEAN countries. Analyzed data comprised results on physical activity, health-related behaviors, mental well-being, and sociodemographic information. A large proportion of university students consumed sugar-sweetened beverages (82.0%; 95%CI: 81.4, 82.6) and snacks/fast food daily (65.2%; 95%CI: 64.4, 66.0). About half (52.2%; 95%CI: 51.4, 53.0) consumed less than the recommended daily …

Using Skills Learned On Campus, Employee And 2-Time Uab Grad Channels Her Passion For Diversity Into Practical Knowledge, Haley Herfurth

Browse All News

No abstract provided.

Clinical Impact Of Nursing Leadership: A Scoping Review, Antonio Palermo, E. Cheda, S. Cavatorti, L. Bonetti, M. Bianchi

General Submissions: Presentations (Oral and Poster)

In Switzerland as well as many other countries, the role of the Clinical Nurse Specialist (CNL/CNS) can be seen within the skill mix, whose leadership is oriented towards patient care at the bedside. To disseminate knowledge about the role and evaluate the possible impact on organizational and clinical practice, a review of the literature was performed based on the question: What impact does Clinical Nursing Leadership have on the quality of patient care?

Training And Education For Advanced Community Care Nurses, Cora O'Leary

General Submissions: Presentations (Oral and Poster)

The aim of this research was to identify training and education needs for advanced community care teams supporting children and young people with complex healthcare needs.

Consideration Of Nutrients Of Public Health Concern Highlighted In The Dietary Guidelines For Americans 2020–2025 Among A Large Sample Of Us Primary Shoppers, Christopher Gustafson, Devin Rose

Department of Agricultural Economics: Faculty Publications

The objective of this research is to estimate the proportion of consumers who consider nutrients identified in the Dietary Guidelines for Americans 2020-2025 (DGA) as being of public health concern during food choice using a large, population-weighted sample of U.S. residents. A question was included in a bi-monthly survey of consumer scanner panel members, asking whether respondents considered each of eight nutrients in a check-all-that-apply format. Four of these nutrients are under-consumed nutrients, while three are nutrients to avoid. Calories was additionally included, as over-consumption of calories causes weight gain. Weighted mean proportions and 95% confidence intervals were …

Increased Cytokine Gene Expression And Cognition Risk Associated With Androgen Deprivation Therapy, Shiv Verma, Prem Prakash Kushwaha, Eswar Shankar, Lee E. Ponsky, Sanjay Gupta

Faculty Scholarship

Background: Androgen deprivation therapy (ADT) is a standard treatment modality for locally advanced, high-risk, and metastatic hormone-sensitive prostate cancer. Long-term ADT treatment likely develops side-effects that include changes in cognition or onset of dementia. However, the molecular understanding of this effect remains elusive. We attempt to establish a link between ADT and changes in cognitive function using patient databases and bioinformatics analyses. Methods: Gene expression profiling was performed using RNA sequencing data from Alzheimer patient cohort and compared with the data from advanced-stage prostate cancer patients receiving neoadjuvant antiandrogen therapy. Differentially expressed genes (DEGs) were analyzed using the Ingenuity knowledge …

Towards Multiplexed And Multimodal Biosensor Platforms In Real-Time Monitoring Of Metabolic Disorders, Sung Sik Chu, Hung Anh Nguyen, Jimmy Zhang, Shawana Tabassum, Hung Cao

Electrical Engineering Faculty Publications and Presentations

Metabolic syndrome (MS) is a cluster of conditions that increases the probability of heart disease, stroke, and diabetes, and is very common worldwide. While the exact cause of MS has yet to be understood, there is evidence indicating the relationship between MS and the dysregulation of the immune system. The resultant biomarkers that are expressed in the process are gaining relevance in the early detection of related MS. However, sensing only a single analyte has its limitations because one analyte can be involved with various conditions. Thus, for MS, which generally results from the co-existence of multiple complications, a multi-analyte …

Mental Health, Chronic Disease, And Substance Use: Findings From Rural Texas, Subi Gandhi, Ryan Glaman, Elizabeth Wachira, Muna Bashir, Sushma Sharma, Chelsea Mowles, Jasmine Luttrell

Journal of Social, Behavioral, and Health Sciences

There are vital links among mental health conditions, chronic diseases, and substance use disorders. Simultaneous examination of the relationship among these three conditions is essential for providing well-integrated care to rural residents who have limited resources and for representing medically underserved areas. We aimed to assess the burden of behavioral health conditions and chronic diseases from a rural Texas community to garner context-specific insights and inform effective health promotion strategies in similar communities. We conducted a cross-sectional study among 181 residents from various zip codes in a rural Texas county. A self-administered, 18-item health-needs questionnaire was used to collect data …

Association Of Cardiovascular Health Through Young Adulthood With Genome-Wide Dna Methylation Patterns In Midlife: The Cardia Study, Yinan Zheng, Brian T Joyce, Shih-Jen Hwang, Jiantao Ma, Lei Liu, Norrina B Allen, Amy E Krefman, Jun Wang, Tao Gao, Drew R Nannini, Haixiang Zhang, David R Jacobs, Myron D Gross, Myriam Fornage, Cora E Lewis, Pamela J Schreiner, Stephen Sidney, Dongquan Chen, Philip Greenland, Daniel Levy, Lifang Hou, Donald M Lloyd-Jones

Faculty, Staff and Student Publications

Background: Cardiovascular health (CVH) from young adulthood is strongly associated with an individual's future risk of cardiovascular disease (CVD) and total mortality. Defining epigenomic biomarkers of lifelong CVH exposure and understanding their roles in CVD development may help develop preventive and therapeutic strategies for CVD.

Methods: In 1085 CARDIA study (Coronary Artery Risk Development in Young Adults) participants, we defined a clinical cumulative CVH score that combines body mass index, blood pressure, total cholesterol, and fasting glucose measured longitudinally from young adulthood through middle age over 20 years (mean age, 25-45). Blood DNA methylation at >840 000 methylation markers was …