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2022

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X-Linked Hypophosphatemia Caused By The Prevailing North American Phex Variant C.*231a>G; Exon 13–15 Duplication Is Often Misdiagnosed As Ankylosing Spondylitis And Manifests In Both Men And Women, Kathryn Mccrystal Dahir, Margo Black, Gary S Gottesman, Erik A Imel, Steven Mumm, Cindy M Nichols, Michael P Whyte Dec 2022

X-Linked Hypophosphatemia Caused By The Prevailing North American Phex Variant C.*231a>G; Exon 13–15 Duplication Is Often Misdiagnosed As Ankylosing Spondylitis And Manifests In Both Men And Women, Kathryn Mccrystal Dahir, Margo Black, Gary S Gottesman, Erik A Imel, Steven Mumm, Cindy M Nichols, Michael P Whyte

2020-Current year OA Pubs

Inactivating mutations of the gene coding for phosphate-regulating endopeptidase homolog X-linked (PHEX) cause X-linked hypophosphatemia (XLH). A novel


The Clinical Spectrum Of Sma-Pme And In Vitro Normalization Of Its Cellular Ceramide Profile, Michelle M Lee, Toni S Pearson, Et Al. Dec 2022

The Clinical Spectrum Of Sma-Pme And In Vitro Normalization Of Its Cellular Ceramide Profile, Michelle M Lee, Toni S Pearson, Et Al.

2020-Current year OA Pubs

OBJECTIVE: The objectives of this study were to define the clinical and biochemical spectrum of spinal muscular atrophy with progressive myoclonic epilepsy (SMA-PME) and to determine if aberrant cellular ceramide accumulation could be normalized by enzyme replacement.

METHODS: Clinical features of 6 patients with SMA-PME were assessed by retrospective chart review, and a literature review of 24 previously published cases was performed. Leukocyte enzyme activity of acid ceramidase was assessed with a fluorescence-based assay. Skin fibroblast ceramide content and was assessed by high performance liquid chromatography, electrospray ionization tandem mass spectroscopy. Enzyme replacement was assessed using recombinant human acid ceramidase …


Bystander Antecedent Scale: Initial Development And Validation, Ashley Jean Friesen-Janochoski Dec 2022

Bystander Antecedent Scale: Initial Development And Validation, Ashley Jean Friesen-Janochoski

Theses and Dissertations

The present study explored the development and initial validation of a measure of bystander intervention behaviors in situations of sexual assault. There is a gap in existing scales using a theoretical basis when measuring bystander behaviors. The scales that do exist focus primary on bystander attitudes and are not theory driven (Banyard et al., 2005; Banyard & Moynihan, 2008; Banyard, 2008; McMahon et al., 2011). Our purpose was to develop and provide initial norming and validity information for the Bystander Antecedent Scale (BAS). The BAS assesses the attitudes, social norms, and behavioral control people experience related to bystander’s behaviors when …


Rsv-Induced Actin Modulation: Contributes To Bronchial Wall Thickening; Does Not Induce Emt, And Is Cdc42-Assisted, Sattya Narayan Talukdar Dec 2022

Rsv-Induced Actin Modulation: Contributes To Bronchial Wall Thickening; Does Not Induce Emt, And Is Cdc42-Assisted, Sattya Narayan Talukdar

Theses and Dissertations

RSV is a negative-sense, single-stranded RNA virus that infects our respiratory tract and can cause severe bronchiolitis and pneumonia worldwide. RSV bronchiolitis causes more fatalities in infants and newborns and leads to severe hospitalization and even death of children. The host-RSV interaction has yet to be explored properly to explain RSV bronchiolitis. This study aimed to elucidate the connection between the modulation of host actin cytoskeletal with viral pathogenesis, including bronchiolitis. As bronchial wall thickening is a common feature of bronchiolitis, the contribution of RSV-infected airway epithelium to bronchial wall thickening was evaluated. RSV infection in the healthy adult bronchial …


Building On The Lasting Benefits Of Attending A Voluntary Prekindergarten Program, Ashley Swickle Dec 2022

Building On The Lasting Benefits Of Attending A Voluntary Prekindergarten Program, Ashley Swickle

Dissertations

The expectations of kindergarten students have drastically changed over the years. Kindergarten students who have not attended a voluntary pre-kindergarten (VPK) program may be at a disadvantage in behavior and academics. The purpose of this study is to show the benefits of a VPK program. My study includes kindergarten students at the school under study whose progress monitoring scores in the beginning of the year are compared to student’s scores who have never attended a VPK program, the amount of behavior referrals is also compared. The anticipated results are that kindergarten students who attended VPK will out-perform their peers who …


Lifestyle Choices Related To Food Consumption And Their Relationship To Depression, Steven L. Jennings Jr. Dec 2022

Lifestyle Choices Related To Food Consumption And Their Relationship To Depression, Steven L. Jennings Jr.

Dissertations

Dieting, or the act of restricting oneself to small amounts or particular kinds of foods on the basis of health, spirituality, lifestyle, and moral decisions, is a practice that dates to 1066 A.D. However, with social media being as influential as it is, one might believe dieting is a new obsession or at least an obsession to which popular culture is returning. Despite this, it is only in recent years that researchers have begun to focus on the health benefits of such behaviors. The present study was designed to take this focus a step further by exploring the potential risks …


Dahlia Cut Flower Production In Utah, Melanie Stock, Amanda Pratt, Claudia Nischwitz, Eli Oliver, Katie Wagner, Nick Volesky Dec 2022

Dahlia Cut Flower Production In Utah, Melanie Stock, Amanda Pratt, Claudia Nischwitz, Eli Oliver, Katie Wagner, Nick Volesky

All Current Publications

Dahlias are tuberous, herbaceous plants that are frost sensitive and therefore grown as a warm-season annual for cut flower production in Utah. Dahlias bloom in summer to fall, with peak production in late summer to early fall, and the season ending with first frost. Plants benefit from pinching to encourage branching and horizontal trellising or staking to promote straight stems and avoid toppling. High tunnels or extended low tunnels with shade, as well as optimum nitrogen and irrigation rates, improve production. As showstoppers in arrangements, dahlia cut flowers are highly desired on local markets and profitable to produce, particularly those …


Mythos, Mattea R. Guldy Dec 2022

Mythos, Mattea R. Guldy

Theses

Mythos is an animated TV series pitch created by Mattea Guldy and Selma Peña. The pitch consists of a pitch deck, a set of 3 scripts, and an animated proof of concept. I worked on the art for the pitch deck as well as the animated proof of concept, while Selma worked on the writing of the pitch deck and the set of 3 scripts. The ultimate goal of our series is to explore the themes of self-love and appreciation through the lens of friendship and comedy. Utilizing mythical creatures as a vessel for a universal appeal to any demographic …


How Do Academic Advisors Intentionally Design Their Office Space To Be More Inviting? A Qualitative Study On Office Décor And Self-Disclosure, Jessica Garcia Dec 2022

How Do Academic Advisors Intentionally Design Their Office Space To Be More Inviting? A Qualitative Study On Office Décor And Self-Disclosure, Jessica Garcia

Theses

Academic advising has been part of institutions of higher education in the United States since the early 19th century. With the rise of incoming students each year and the wide range of majors and programs colleges offer, advisors are necessary to help guide students through their academic careers. This paper presents a qualitative study on how advisors intentionally create a space that encourages communication and collaboration within an advisor-advisee relationship. The theoretical framework used in this study is Social Penetration Theory, which suggests that facilitating self-disclosure will also support relationship development. For this research, academic advisors working at two different …


"Can You Please Turn Your Cameras On?" Communication Apprehension And Teleconferencing, Emily James Mcindoe Dec 2022

"Can You Please Turn Your Cameras On?" Communication Apprehension And Teleconferencing, Emily James Mcindoe

Theses

With the onset of the COVID-19 pandemic, a multitude of normalities in individuals' lives had to change to continue moving forward. The world began to embrace new technologies that allowed individuals to be connected while physically apart. One of the most embraced technologies was teleconferencing. Teleconferencing is not a new technology with the first primitive form being created in 1968, however, it was not until the world had to embrace teleconferencing during the COVID-19 pandemic did the technologies became a common part of everyday life. The term Zoom is now synonymous with video chatting and conferencing becoming a part of …


Rite Of Identity, Youmee Lee Dec 2022

Rite Of Identity, Youmee Lee

Theses

Rite of Identity, a graduate thesis film, is a 2D animated visual poem of deaf children’s experiences. The film follows the protagonist’s journey in navigating a visual realm and a black-and-white realm, which represent the deaf world and the hearing world. Childhood experiences of struggling to assimilate into mainstream society are conveyed through the protagonist in the black-and-white realm. The purpose of the film is to encourage the viewers to think about what it is like for a child to be underestimated and to struggle with a soundscape that is not perceived naturally in the realm. Deaf children have a …


Balanced Ar Glasses System Between Text And Image Information Helps People Get A Better Reading Skill, Libo Jiang Dec 2022

Balanced Ar Glasses System Between Text And Image Information Helps People Get A Better Reading Skill, Libo Jiang

Theses

Nowadays, people prefer browsing images and videos on their phones rather than reading a book (Thain 2018). Even if they decide to read something, they are still heavily distracted by electronic devices. In my thesis, I’m trying to balance the visual and text information and help people to stay more focused while reading. My solution: Focus is an AR glasses system that recognizes the contents users are viewing and records users’ reading and image browsing time. And users have to earn image/video time by reading the text. The glasses block images/videos if they run out of image time.


Light Scattering Study Of An Important Eye Lens Protein: Beta Crystallin, Malcolm F. Larose Dec 2022

Light Scattering Study Of An Important Eye Lens Protein: Beta Crystallin, Malcolm F. Larose

Theses

Light scattering experiments were performed on bovine βH crystallin, an important protein component of the mammalian eye lens. Light scattering results are compared to simplified models for the free energy of mixing of β crystallins with water. The static light scattering data are well-represented by hard convex body equations of state having dimensionless non-sphericity coefficients of close to 2, compatible with prolate spherocylinders, and weight-average molecular weights ranging between 2−5×105 g/mole. Additionally, quasi-elastic light scattering data was obtained which shows that βH has a hydrodynamic radius near 7.3 nm. These experiments extend light scattering work on β crystallins well into …


The Role Social Media Influencers Play In A Company's Brand, Taylor Todi Dec 2022

The Role Social Media Influencers Play In A Company's Brand, Taylor Todi

Theses

Influencer marketing is a tactic that many companies have had to integrate into their businesses to better communicate with consumers. The purpose of this research is to analyze the role influencer marketing plays in a company's brand. This study assesses the way consumers build trust and relationships with companies through the help of influencers. There are many variables that come into play, for example, emotional attachment, authenticity, and loyalty are just three that have been measured in previous studies. These same variables are used in this research to see if they can also apply to a company that uses influencers …


Protectbot: A Chatbot To Protect Children On Gaming Platforms, Anum Faraz Dec 2022

Protectbot: A Chatbot To Protect Children On Gaming Platforms, Anum Faraz

Theses

Online gaming no longer has limited access, as it has become available to a high percentage of children in recent years. Consequently, children are exposed to multifaceted threats, such as cyberbullying, grooming, and sexting. The online gaming industry is taking concerted measures to create a safe environment for children to play and interact with, such efforts remain inadequate and fragmented. Different approaches utilizing machine learning (ML) techniques to detect child predatory behavior have been designed to provide potential detection and protection in this context. After analyzing the available AI tools and solutions it was observed that the available solutions are …


Plastic Pollution Requires An Integrative Systems Approach To Understand And Mitigate Risk, Winnie Courtene-Jones, Nathaniel J. Clark, Richard C. Thompson Dec 2022

Plastic Pollution Requires An Integrative Systems Approach To Understand And Mitigate Risk, Winnie Courtene-Jones, Nathaniel J. Clark, Richard C. Thompson

School of Biological and Marine Sciences

To date, much effort has been placed on quantifying plastic pollution and understanding its negative environmental effects, arguably to the detriment of research and evaluation of potential interventions. This has led to piecemeal progress in interventions to reduce plastic pollution, which do not correspond to the pace of emissions. For substances that are used on a global scale and identified as hazardous, there is a need to act before irreversible damage is done. For example, the history of dichlorodiphenyltrichloethane's (DDT) use has demonstrated that legacy chemicals with properties of persistence can still be found in the environment despite being first …


Development And Feasibility Testing Of An Evidence-Based Occupational Therapy Program For Adults With Both Down Syndrome And Dementia, Sujatha E. Raj, Shylie Mackintosh, Jocelyn Kernot, Caroline Fryer, Mandy Stanley Dec 2022

Development And Feasibility Testing Of An Evidence-Based Occupational Therapy Program For Adults With Both Down Syndrome And Dementia, Sujatha E. Raj, Shylie Mackintosh, Jocelyn Kernot, Caroline Fryer, Mandy Stanley

Research outputs 2022 to 2026

This paper describes the development of a home-based occupational therapy intervention program for people with Down syndrome who experience early on-set dementia causing a decline in their performance skills and increasing care dependency on their informal caregivers. A six-step methodological process adapted from the Medical Research Council framework for developing and evaluating complex interventions was formulated to develop an evidence-based occupational therapy program for people with both Down syndrome and dementia and their informal caregivers. The first two steps gathered evidence through systematic reviews of the literature and determined the scope of current occupational therapy practice. The gathered evidence was …


Pathogenic Potential Of Respirable Spodumene Cleavage Fragments Following Application Of Regulatory Counting Criteria For Asbestiform Fibres, Melinda Gardner, Martyn Cross, Sue Reed, Maggie Davidson, Rick Hughes, Jacques Oosthuizen Dec 2022

Pathogenic Potential Of Respirable Spodumene Cleavage Fragments Following Application Of Regulatory Counting Criteria For Asbestiform Fibres, Melinda Gardner, Martyn Cross, Sue Reed, Maggie Davidson, Rick Hughes, Jacques Oosthuizen

Research outputs 2022 to 2026

Health risks from exposure to lithium-bearing spodumene cleavage fragments are unknown. While asbestiform fibres can lead to fibrosis, mesothelioma and lung cancer, controversy remains whether non-asbestiform cleavage fragments, having equivalent dimensions, elicit similar pathologic responses. The mineralogy of respirable particles from two alpha (α) - spodumene concentrate grades (chemical and technical) were characterised using semi-quantitative X-ray diffraction (XRD). Particles were measured using scanning electron microscopy (SEM) and the dimensions (length [L], diameter [D], aspect ratio [AR]) applied to regulatory counting criteria for asbestiform fibres. Application of the current World Health Organization (WHO) and National Occupational Health and Safety Commission (NOHSC) …


Re-Imaging The Future In Urban Studies And Built Environment Discourse: A Neurourbanism Perspective, Emeka Ndaguba, Jua Cilliers, Sijekula Mbanga, Kerry Brown, Sumita Ghosh Dec 2022

Re-Imaging The Future In Urban Studies And Built Environment Discourse: A Neurourbanism Perspective, Emeka Ndaguba, Jua Cilliers, Sijekula Mbanga, Kerry Brown, Sumita Ghosh

Research outputs 2022 to 2026

Neurological constructs are being applied in various fields; within urban studies and built environments, neurourbanism stands out. To understand this concept, this study seeks to conduct a scientometric analysis of the concept of neurourbanism. To do so, we gauged the intellectual structure and clarified the influencers and emerging themes while seeking to identify essential gaps in neurourbanism research in urban studies and the built environment. Data were sorted from Dimensions Artificial Intelligence platform because of its reliability in providing the needed dataset accurately, and the Citespace software was used to analyze the data. Our results suggest plurality in explaining the …


Psychedelic Forum Member Preferences For Carer Experience And Consumption Behavior: Can “Trip Sitters” Help Inform Psychedelic Harm Reduction Services?, Liam B. Engel, Sascha B. Thal, Stephen J. Bright Dec 2022

Psychedelic Forum Member Preferences For Carer Experience And Consumption Behavior: Can “Trip Sitters” Help Inform Psychedelic Harm Reduction Services?, Liam B. Engel, Sascha B. Thal, Stephen J. Bright

Research outputs 2022 to 2026

Background: There is limited research on the provision of harm reduction services to people who use psychedelics. Little is known about provision of care to people consuming psychedelics outside of clinical trials.

Methods: We investigated how people who used psychedelics discussed their preferences for care (or “trip sitting”) on two online forums: The Shroomery and DMT Nexus. A thematic analysis of the discussion was conducted to better understand consumer preferences for harm reduction services and resources.

Conclusion: Demand for trip sitters with lived psychedelic experience is likely influenced by stigma and empathy. Trip sitters who could relate to the effects …


Common Weights Analysis Of Renewable Energy Efficiency Of Oecd Countries, Reza Kiani Mavi, Neda Kiani Mavi, Reza Farzipoor Saen, Mark Goh Dec 2022

Common Weights Analysis Of Renewable Energy Efficiency Of Oecd Countries, Reza Kiani Mavi, Neda Kiani Mavi, Reza Farzipoor Saen, Mark Goh

Research outputs 2022 to 2026

Arising from the recent COP26 climate change conference, many governments have emphasised carbon neutrality targets for environmental sustainability by increasing renewable energy efficiency. This study develops a common set of weights (CSW) model for the additive model in data envelopment analysis using goal programming to analyse the energy efficiency of the Organisation for Economic Co-operation and Development (OECD) countries. The CSW model, which has better discrimination power, places Iceland as the most renewable energy-efficient member country in the OECD, followed by Luxemburg and Norway. Our findings suggest that OECD countries should increase their renewable energy consumption and reduce municipal waste …


“Why Don’T I Look Like Her?” How Adolescent Girls View Social Media And Its Connection To Body Image, Alana Papageorgiou, Colleen Fisher, Donna Cross Dec 2022

“Why Don’T I Look Like Her?” How Adolescent Girls View Social Media And Its Connection To Body Image, Alana Papageorgiou, Colleen Fisher, Donna Cross

Research outputs 2022 to 2026

Background: Adolescent girls appear more vulnerable to experiencing mental health difficulties from social media use than boys. The presence of sexualized images online is thought to contribute, through increasing body dissatisfaction among adolescent girls. Sexual objectification through images may reinforce to adolescent girls that their value is based on their appearance. This study explored how sexualized images typically found on social media might influence adolescent girls’ mental health, in positive and/or negative ways. Methods: In-depth interviews were conducted with girls aged 14–17 years (n = 24) in Perth, Western Australia. Data were analyzed using thematic analysis. Results: Participants identified body …


No Theory Solution Focused Practices Is A Way Of Life: A Further Step To An Ecology Of Mind, Nick Drury Dec 2022

No Theory Solution Focused Practices Is A Way Of Life: A Further Step To An Ecology Of Mind, Nick Drury

Journal of Solution Focused Practices

No abstract provided.


How Does Social Media Use Affect Creativity?, Fardina S. Rahman Dec 2022

How Does Social Media Use Affect Creativity?, Fardina S. Rahman

Creativity and Change Leadership Graduate Student Master's Projects

Social media is a parasitic relationship that is more beneficial for data companies and the platforms than it is the user. However, users still reap many unexpected benefits from engaging with different socials. Through observing how users interact with the platforms and each other using a Creativity focused framework, it is quite observable social media can be an effective tool to improve one’s creativity if used properly. Social media facilitates a combination of humor and community in a way that is difficult for traditional media and community to replicate. While humor inspires positive emotion and novelty and laughter binds a …


Professional Sports Organizations And Business Analytics: Monopoly Power Vs Debt Financing, Mike Troilo, Adrien Bouchet Dec 2022

Professional Sports Organizations And Business Analytics: Monopoly Power Vs Debt Financing, Mike Troilo, Adrien Bouchet

Journal of Applied Sport Management

In this essay, we consider the factors that explain the reticence of PSOs to be early adopters of analytics. We examine the relatively privileged position that professional sports franchises at the highest echelon in the U.S. and Canada enjoy and compare it the industry dynamics firms face in competitive environments. We remark upon the expansion of the league via debt financing, and why that promotes increased use of analytics. We also offer several propositions about the growth of analytics, and we conclude with some thoughts about what the future may hold for PSOs and analytics.


Analytics On Service Quality In Spectator Sports, Ahmet Ozkul, Gazi Duman Dec 2022

Analytics On Service Quality In Spectator Sports, Ahmet Ozkul, Gazi Duman

Journal of Applied Sport Management

Spectator sport events are made possible by the contributions of many different participants ranging from fans and players to coaches, managers and sponsors. Through the lens of co-creation of value in the spectator sports, we discuss how sport analytics can relate to spectator sport service quality by collecting and analyzing data from each participating actor.


Facilitators And Inhibitors To First Adult Care Visits In The Transition From Paediatric To Adult Orientated Inflammatory Bowel Disease Healthcare, Joanna Rea Dec 2022

Facilitators And Inhibitors To First Adult Care Visits In The Transition From Paediatric To Adult Orientated Inflammatory Bowel Disease Healthcare, Joanna Rea

Theses

Background: Inflammatory bowel disease (IBD) can be a very debilitating disease and it is found to be more extensive in children with rapid early progression (Van Limbergen et al., 2008). As adolescents, these children transition from paediatric to adult oriented care. The first adult care visits are a pivotal phase of a successful transition process, where adolescents potentially begin to actively take control of their disease. The aim of this study is to explore the inhibitors and facilitators to first adult care visits in the transition process from paediatric to adult oriented IBD healthcare.

Methods: An exploratory, descriptive, qualitative approach …


Introduction: 14(5) 2022: Independent And Special Issue, Rosalind Latiner Raby Dec 2022

Introduction: 14(5) 2022: Independent And Special Issue, Rosalind Latiner Raby

Journal of Comparative & International Higher Education

No abstract provided.


The Education Process Of Children With Imprisoned Parents After The July 15, 2016 Coup Attempt In Turkey Dec 2022

The Education Process Of Children With Imprisoned Parents After The July 15, 2016 Coup Attempt In Turkey

Journal of Comparative & International Higher Education

No abstract provided.


Acculturation And Social Media: How Do International Students Engage With Facebook While Abroad? Dec 2022

Acculturation And Social Media: How Do International Students Engage With Facebook While Abroad?

Journal of Comparative & International Higher Education

No abstract provided.