Digital Commons Network^™

Preparing For Usability Testing, Lindsey Skaggs, Chad M. Kahl

Faculty and Staff Publications – Milner Library

No abstract provided.

Sugar Freed, Sarah Gaygen

Theses

Sugar Freed is a 2D digitally animated short film about a little girl named Molly, who gets fed up with her mother, a dentist, and ends up in a candy world ruled by evil gummy bears. Sugar Freed’s message evolved over time from a simple warning against sugar, to a child gaining an understanding of why her mother’s lessons are necessary, stemming from parts of my own childhood. The purpose of this film was to see if I could find the right balance between time management and quality control to produce an animated short that was well over four-minutes long, …

Egfr-Phosphorylated Gdh1 Harmonizes With Rsk2 To Drive Creb Activation And Tumor Metastasis In Egfr-Activated Lung Cancer, Jihoon Kang, Jaemoo Chun, Jung Seok Hwang, Chaoyun Pan, Jie Li, Austin C Boese, Isabelle Young, Courteney M Malin, Yibin Kang, Don L Gibbons, Gabriel Sica, Haian Fu, Suresh S Ramalingam, Lingtao Jin, Sumin Kang

Faculty, Staff and Student Publications

The cancer metastasis process involves dysregulated oncogenic kinase signaling, but how this orchestrates metabolic networks and signal cascades to promote metastasis is largely unclear. Here we report that inhibition of glutamate dehydrogenase 1 (GDH1) and ribosomal S6 kinase 2 (RSK2) synergistically attenuates cell invasion, anoikis resistance, and immune escape in lung cancer and more evidently in tumors harboring epidermal growth factor receptor (EGFR)-activating or EGFR inhibitor-resistant mutations. Mechanistically, GDH1 is activated by EGFR through phosphorylation at tyrosine 135 and, together with RSK2, enhances the cAMP response element-binding protein (CREB) activity via CaMKIV signaling, thereby promoting metastasis. Co-targeting RSK2 and GDH1 …

Psychoactive Space: Glimpses Of The Unknown, Mathew Emmett

School of Art, Design and Architecture

No abstract provided.

Do Message Framing And Source Credibility Matter? : Examining Framed Covid- 19 Prevention Messaging In Saudi Arabia, Mona Alsheddi

Journal of Educational and Psychological Studies

This paper aims to examine the influence of different message framings (utilitarian, deontological, religious, virtue-based message, and God's punishment-based messages) on Saudi Arabians’ beliefs and behavioral intentions related to COVID-19 and the influence of message source (religious advocate, Saudi COVID-19 monitoring committee member, close person, physician, journalist, and social media influencer) on communicating messages in the COVID-19 pandemic context. The between-subject design experiment (n =222) was conducted online due to the Covid-19 restrictions in force at the time of this study and in an attempt to derive a representative sample from the general Saudi population. The results showed that the …

Scientology's Faq: Sciencing, Tech-Romancing, Simulacra, & Simulation An Estranged Content Analysis, David Scott Morrill

Dissertations and Theses

This thesis examines how the practice of sciencing, tech-romancing, simulacra, and simulation manifests in both the text and symbols used on audiences of the Church of Scientology’s outreach materials. It specifically examines its official FAQ page. Self-framing was observed that satisfied the definition of sciencing and tech-romancing. Under an Estranged approach, Morrill examined selections of the Church’s FAQ pages, coding for instances of sciencing, tech-romancing, simulacra, and simulation. The data indicate that the Church frequently adopts simulacra and engages in simulation. The Church was seen frequently adopting technological and scientific symbols and jargon. The degree of sciencing, tech-romancing, simulacra, and …

Effect Of Plasma Treatment On Soil Degradation Of A Biodegradable Mulch Film, Swapnil Bhattacharya

Theses

Biodegradable Mulch Films (BMFs) offer a sustainable alternative to traditional non-degradable PE mulch films. However, their slow rate of biodegradation can lead to plastics accumulation in the soil. In this study, a commercially available BMF based on polybutylene adipate co-terephthalate (PBAT) and polylactic acid (PLA) is examined. Here the effects of gliding arc plasma treatment on the bulk and surface properties, as well as its soil degradation behavior, is studied. An increase in surface oxygen containing species and hydrophilicity was observed following plasma treatment. Only a small hydrophobic recovery was noted over 30 days. No changes in the bulk polymer …

Neuronal Signal-Regulatory Protein Alpha Drives Microglial Phagocytosis By Limiting Microglial Interaction With Cd47 In The Retina, Danye Jiang, Courtney A Burger, Viktor Akhanov, Justine H Liang, Robert D Mackin, Nicholas E Albrecht, Pilar Andrade, Dorothy P Schafer, Melanie A Samuel

Center on Aging Staff Publications

Microglia utilize their phagocytic activity to prune redundant synapses and refine neural circuits during precise developmental periods. However, the neuronal signals that control this phagocytic clockwork remain largely undefined. Here, we show that neuronal signal-regulatory protein alpha (SIRPα) is a permissive cue for microglial phagocytosis in the developing murine retina. Removal of neuronal, but not microglial, SIRPα reduced microglial phagocytosis, increased synpase numbers, and impaired circuit function. Conversely, prolonging neuronal SIRPα expression extended developmental microglial phagocytosis. These outcomes depended on the interaction of presynaptic SIRPα with postsynaptic CD47. Global CD47 deficiency modestly increased microglial phagocytosis, while CD47 overexpression reduced it. …

Gata1 Controls Numbers Of Hematopoietic Progenitors And Their Response To Autoimmune Neuroinflammation, Daniel Hwang, Larissa Ishikawa, Maryam S. Seyedsadr, Elisabeth R. Mari, Ezgi Kasimoglu, Ziver Sahin, Alexandra Boehm, Soohwa Jang, Javad Rasouli, Courtney Vaccaro, Michael Gonzalez, Hakon Hakonarson, Mohamad Rostami, Guang-Xian Zhang, Bogoljub Ciric

Department of Neurology Faculty Papers

GATA-binding factor 1 (GATA1) is a transcription factor that governs the development and function of multiple hematopoietic cell lineages. GATA1 is expressed in hematopoietic stem and progenitor cells (HSPCs) and is essential for erythroid lineage commitment; however, whether it plays a role in hematopoietic stem cell (HSC) biology and the development of myeloid cells, and what that role might be, remains unclear. We initially set out to test the role of eosinophils in experimental autoimmune encephalomyelitis (EAE), a model of central nervous system autoimmunity, using mice lacking a double GATA-site (ΔdblGATA), which lacks eosinophils due to the deletion of the …

Use Of An Interactive Obesity Treatment Approach In Individuals With Severe Mental Illness: Feasibility, Acceptability, And Proposed Engagement Criteria, Ginger Nicol, Madeline Jansen, Rita Haddad, Amanda Ricchio, Michael D Yingling, Julia A Schweiger, Katie Keenoy, Bradley A Evanoff, John W Newcomer

2020-Current year OA Pubs

BACKGROUND: Digital and mobile health interventions are increasingly being used to support healthy lifestyle change, including in certain high-risk populations such as those with severe mental illnesses (SMIs). Life expectancy in this population lags 15 years behind counterparts in the general population, primarily due to obesity-related health conditions.

OBJECTIVE: We tested the feasibility and usability of a 12-week interactive obesity treatment approach (iOTA) to adults with chronic SMIs (depression, bipolar disorder and schizophrenia spectrum disorder) receiving treatment in community settings. The iOTA incorporates short message service (SMS) text messages to supplement monthly in-person health coaching.

METHODS: Factors hypothesized to be …

Rapid Astrocyte-Dependent Facilitation Amplifies Multi-Vesicular Release In Hippocampal Synapse, Jongyun Myeong, Vitaly A Klyachko

2020-Current year OA Pubs

Synaptic facilitation is a major form of short-term plasticity typically driven by an increase in residual presynaptic calcium. Using near-total internal reflection fluorescence (near-TIRF) imaging of single vesicle release in cultured hippocampal synapses, we demonstrate a distinctive, release-dependent form of facilitation in which probability of vesicle release is higher following a successful glutamate release event than following a failure. This phenomenon has an onset of ≤500 ms and lasts several seconds, resulting in clusters of successful release events. The release-dependent facilitation requires neuronal contact with astrocytes and astrocytic glutamate uptake by EAAT1. It is not observed in neurons grown alone …

Topics And Sentiment Surrounding Vaping On Twitter And Reddit During The 2019 E-Cigarette And Vaping Use-Associated Lung Injury Outbreak: Comparative Study, Dezhi Wu, Erin Kasson, Avineet Kumar Singh, Yang Ren, Nina Kaiser, Ming Huang, Patricia A Cavazos-Rehg

2020-Current year OA Pubs

BACKGROUND: Vaping or e-cigarette use has become dramatically more popular in the United States in recent years. e-Cigarette and vaping use-associated lung injury (EVALI) cases caused an increase in hospitalizations and deaths in 2019, and many instances were later linked to unregulated products. Previous literature has leveraged social media data for surveillance of health topics. Individuals are willing to share mental health experiences and other personal stories on social media platforms where they feel a sense of community, reduced stigma, and empowerment.

OBJECTIVE: This study aimed to compare vaping-related content on 2 popular social media platforms (ie, Twitter and Reddit) …

Pembentukan Holding Company Badan Usaha Milik Negara (Bumn) Di Sektor Infrastruktur Ditinjau Dalam Persaingan Usaha Tidak Sehat, Wiesma Mara Rangga

"Dharmasisya” Jurnal Program Magister Hukum FHUI

That a large number of state-owned enterprises (SOEs) in infrastructure has caused competition, especially when competing against one another in participating in the same tender. This is not in line with the synergy plan between SOEs, which is one of the essential pillars. SOEs belonging to similar value chain groups should work together to accelerate economic growth and synergies at various levels through corporate, transaction, and operational restructuring. Optimizing the formation of infrastructure holding can be done through collaboration and synergy between SOE entities, strengthening and increasing the capacity of each holding member, and integrating infrastructure development. However, the plan …

Perbandingan Sistem Hukum Civil Law Dan Common Law Dalam Penerapan Yurisprudensi Ditinjau Dari Politik Hukum, Praise Juinta W.S. Siregar

"Dharmasisya” Jurnal Program Magister Hukum FHUI

The legal system is related to the concept of law, where the two things have an inseparable relationship with each other. In principle, the legal system regulates the life of a community so that conflicts do not occur, where if the conflict is unavoidable, then the legal system has an important role in resolving the conflict. The legal system in the judiciary has a major influence in the application of the law, especially for judges in examining and deciding a case. The Panel of Judges in deciding a case will definitely pay close attention to the legal system in its …

Kebijakan Countercyclical Sebagai Upaya Kesejahteraan Masyarakat, Made Cinthya Puspita Shara

"Dharmasisya” Jurnal Program Magister Hukum FHUI

Indonesia's high level of economic growth is in line with the development of businesses that increase capital by making credit agreements with financial institutions. However, the state spread of the co-19 pandemic case has been declared a national disaster, impacting the implementation of credit agreements between the debtor and financial institutions. Economic problems make it difficult for people to carry out their obligations. A countercyclical buffer policy is a buffer that is carried out by providing additional capital to replace losses if excessive credit growth occurs, which has the potential to disrupt financial stability. Bank Indonesia Policy PBI No.17/22/PBI/2015, also …

Pengelolaan Royalti Dari Pencipta Lagu Yang Tidak Terdaftar Di Lembaga Manajemen Kolektif Oleh Lembaga Manajemen Kolektif Nasional, Mohamad Thaufiq Rachman

"Dharmasisya” Jurnal Program Magister Hukum FHUI

Royalty is a reward received by the author or owner of the related right concerning the utilization of their Economic Rights following Article 1 point 21 of Law No. 28, 2014 regarding Copyright ("UUHC 2014"). Royalty could also be interpreted as a form of appreciation for the Author's Works, such as song and/or music. Encouraging the spirit of industry players, including songwriters, is essential for continuous growth. As mentioned in the general explanation section of UUHC 2014, Copyright is the most important basis of the national creative economy. With the fulfillment of the protection and development of this creative economy, …

Perspektif Kitab Undang-Undang Hukum Perdata Dan Uu Nomor 13 Tahun 2003 Tentang Ketenagakerjaan Terkait Dengan Perlindungan Hukum Terhadap Pengusaha Terhadap Wanprestasi Ikatan Dinas Yang Dilakukan Oleh Pekerja, Lia Amalia

"Dharmasisya” Jurnal Program Magister Hukum FHUI

Labor issues cannot be separated from the Agreement between the Worker and the Employer, both as the initial Agreement when implementation or an additional Agreement such as the official bond Agreement. Law No.13 of 2003 on Manpower has regulated that every employee who is bound by a contract to work for/ serve the enterprise for a certain period in return for training or education. She/He is not allowed to resign during the term of the official binding Agreement. The legal consequences for violations are fine in the form of money. In this case, Gresik District Court on August 2014 decided …

Perlindungan Konsumen Startup Digital Yang Bergerak Di Bidang Layanan Urun Dana Melalui Penawaran Saham Berbasis Teknologi Informasi Dalam Sistem Hukum Indonesia, Juliyani Purnama Ramli

"Dharmasisya” Jurnal Program Magister Hukum FHUI

The existence of equity crowdfunding is one of the solutions for micro, small, and medium enterprises financing. The government already regulates equity crowdfunding matters by Financial Service Authority Number 37/POJK.04/2018 concerning equity crowdfunding. The problem is that the state has not fully protected consumers of equity crowdfunding. Its because the definition of equity crowdfunding consumer does not fulfill the consumer elements in Consumer Protection Regulation. The Financial Service Authority has not explicitly regulated consumer protection yet, even though equity crowdfunding has a great opportunity to develop and be used by the community directly.

Keywords: equity crowdfunding, financial service authority, and …

Pengujian Tindakan Penyalahgunaan Wewenang Pejabat Di Pengadilan Tata Usaha Negara, Bob Humisar Simbolon

"Dharmasisya” Jurnal Program Magister Hukum FHUI

The examination of the Abuse of Authority in the State Administrative Court is an administrative act or action that must be based on the existing laws and regulations. However, along with the growing understanding of the state of material law, the understanding that government based on laws has shifted to an understanding of state government based on law. The purpose of this paper is to see the extent of the authority of the State Administrative Court in examining territorial boundaries and the authorized procedures at the State Administrative Court. The research method is in the form of normative juridical research …

Penanganan Situs Internet Bermuatan Negatif, Muhammad Farhansyah Hamid

"Dharmasisya” Jurnal Program Magister Hukum FHUI

This paper discusses the concept of an internet site that is defined to be negative and how the Indonesian law regulates it, and about the mechanism of negative site handling based on peraturan menteri komunikasi dan informasi nomor 19 tahun 2014. Furthermore, it will be discussed about the human rights to have access to the information and how negative content handling is related to it. This legal research uses a normative juridical approach with secondary data from national, regulations, books, and interviews with sources. The result of this research is that content handling is so related to limitation of human …

Konversi Akad Ijarah Al-Muntahiya Bi Al-Tamlik (Imbt) Menjadi Akad Mudharabah, Ana Eka Fitriani

"Dharmasisya” Jurnal Program Magister Hukum FHUI

POJK No.29/POJK.03/2019 about Earning Asset Quality and Establishment of Allowance for Earning Asset Losses for Islamic Rural Banks states that one of the conversions that can be done is the conversion of Ijarah Al-Muntahiya Bi Al-Tamlik (IMBT) contract to Mudharabah contract. When IMBT is converted into Mudharabah contract, at the end of IMBT contract the debtor can’t have the object. Because, the object turned into capital that was given by Shahib al-Mal to Mudharib. There is an adversity that is more detrimental to one party and beneficial to the other. If there is a conflict between adversity and benefit, then …

Implementasi Peraturan Daerah Dalam Otonomi Daerah Menjadi Salah Satu Parameter Good Governance, Ananda Rayhana Putri

"Dharmasisya” Jurnal Program Magister Hukum FHUI

Regional Regulation as one of the regional legal products is something inherent with the Regional Autonomy system. This is a consequence of the regional autonomy system itself which is based on independence and is not a form of freedom of an independent government unit. Independence itself means that the Region has the right to regulate and manage the domestic affairs of its own government. The authority to regulate here means that the region has the right to make legal decisions in the form of laws and regulations. In forming a region it is not easy because it requires sufficient knowledge …

Perbandingan Hukum Rahasia Dagang Indonesia Dengan Amerika Serikat, Monica Yesica Febrina

"Dharmasisya” Jurnal Program Magister Hukum FHUI

Legal protection of intellectual property is an important element in supporting creativity and trade. Indonesia has ratified the Agreement and Trade Related Aspects of Intellectual Property Rights and has enacted Law number 30 of 2000 concerning Trade Secret. Legal protection of trade secrets aims to protect business actors in trade practices both regionally and internationally. In addition, protection of trade secrets can prevent unfair business competition. Thus, business people have wider opportunities to develop their creativity and business. This research method is a normative research with comparative research type. This study examines the comparison of intellectual property protection laws specifically …

Perlindungan Bagi Nasabah Dalam Penyelenggaraan Layanan Perbankan Digital Di Indonesia, Melia Prabangasta Yustisia

"Dharmasisya” Jurnal Program Magister Hukum FHUI

The development of digital banking services in Indonesia is growing along with the increasingly intense competition in the banking industry. The internet changed the paradigm in terms of communication and business, where the development of these technologies brought changes in banking business activities towards digital banking. Customers can access financial services only by using mobile phones, easily conduct banking service transactions using various methods ranging from short message service (SMS) Banking to internet banking, access banking services without visiting the branch office but through application services from each bank. However, the development of digital banking services needs to be followed …

Aransemen Kontemporer Musik Tradisional Sebagai Inovasi Pemajuan Kebudayaan Dalam Lingkup Hak Kekayaan Intelektual, Mohammad Ryan Hernandi

"Dharmasisya” Jurnal Program Magister Hukum FHUI

Traditional Knowledge and Traditional Cultural Expressions are traditional forms of intellectual property that are closely related to copyright within the scope of Intellectual Property Rights (IPR). Among the various types of Expressions of Folklore in Indonesia, traditional music and songs are one of them. Traditional music is music or sound art found in various regions of Indonesia that is born and develops and is passed down from one generation to the next. Traditional music usually uses the language, style, and traditions of the region it originates from. The traditional music of each region has its own characteristics, for example, the …

Perlindungan Hak Cipta Terhadap Penggandaan Permainan Video (Copyright Protection Against Video Game Copying), Ahmad Fajri Wibowo

"Dharmasisya” Jurnal Program Magister Hukum FHUI

Copyright protection provides legal protection to creative industries. One of the creative industries that need to be protected is the video game industry. The development of video games in Indonesia is very fast, therefore legal protection is needed to maintain the development of the video game industry. Basically a video game is an object of creation contained in Law Number 28 of 2014 concerning copyright. In the development of the video game industry, there are problems that occur such as the number of illegal copies of video games. Thus, copyright protection plays a very important role in maintaining the video …

Akad Wakalah Bil Ujrah Dan Akad Qard Dalam Penerapan Akad Pembelian Barang, Zendy Sellyfio Ardiana

"Dharmasisya” Jurnal Program Magister Hukum FHUI

The wakalah bil ujrah and qard contract are contracts that often cause difficulties in implementing the purchase of goods in everyday life, both in safekeeping for purchasing goods and for buying and selling in general. Where if it is wrong in its application, it can cause income in a sale and purchase to be haraam due to an error in understanding the contract used and not describing benefit as the core of maqashid al-sharia which has an important role in determining Islamic law. The purpose of this paper is to find out how the solution to the application of each …

Perlindungan Hukum Atas Ulos Sebagai Ekspresi Budaya Tradisional, Yoshua Ruselvelt P Sidabutar

"Dharmasisya” Jurnal Program Magister Hukum FHUI

Traditional cultural expressions are a way of life for the Indonesian nation that teaches traditions, wisdom, values, communal knowledge packaged and passed on to posterity through tales, legends, arts and ceremonies which gradually form the social norms and way of life of the Indonesian nation. Indonesia is a country that consists of various tribes and cultures so that it has priceless Traditional Cultural Expressions and really needs to be protected. One form of traditional cultural expression in Indonesia is ulos cloth, which is a fabric product that is known internationally. This research uses juridical-normative legal research, where in collecting writing …

Perbedaan Equity Crowdfunding Dan Initial Public Offering (Ipo) Dalam Hukum Pasar Modal Indonesia, Widya Rahmadhani

"Dharmasisya” Jurnal Program Magister Hukum FHUI

Equity Crowdfunding is newly known in Indonesia. Indonesia’s Financial Services Authority passed new regulation that regulating Equity Crowdfunding through Indonesia Financial Services Authorities Rule Number 37/POJK.04/2018 regarding Equity Crowdfunding. Equity Crowdfunding concept considered similar to Initial Public Offering (IPO). Further, this research objective is to analyze Equity Crowdfunding from Indonesia’s Capital Market Law Perspective to find out if Equity Crowdfunding is remarkably similar to Initial Public Offering (IPO). This research is a normative study using documentary studies in the form of secondary data. The research was found that although there are similarities on the main concept between Equity …

Perlindungan Hukum Bagi Konsumen Terhadap Transaksi Jual Beli Melalui Platform E-Commerce Di Indonesia, Viola Annisa Ikhsan

"Dharmasisya” Jurnal Program Magister Hukum FHUI

With the entry of internet media in the world of commerce / business, many things have changed, namely the closeness between sellers and buyers in transactions has become increasingly tenuous, because each party does not know each other closely and is known only through internet media. Other obstacles that will arise from transactions via the internet include legal protection for buying and selling transactions made through the E-Commerce platform in Indonesia. In fact, the Consumer Protection Law (UUPK) and the Information and Electronic Transaction Law (UUITE) have been able to provide adequate legal protection for consumers in making transactions via …