Digital Commons Network^™

Systematic Review Of A Ramsar Wetland And Unesco Biosphere Reserve In A Climate Change Hotspot (Ichkeul Lake, Tunisia), Sabrine Sahbani, Béchir Béjaoui, Sihem Benabdalla, Rachid Toujani, Afef Fathalli, Noureddine Zaaboub, Jalel Aouissi, Zeineb Kassouk, Nabil Hamdi, Nabiha Ben Mbarek, Hechmi Missaoui, Leila Basti, Reginald Blake, Hamidreza Norouzi

Publications and Research

Tunisia's Ichkeul Lake is among the most productive ecosystems in the Mediterranean, with a great regional value thanks to its diversity of habitats. It is an important overwintering area for waterfowl species. It is a RAMSAR wetland, a National Park, a UNESCO World Heritage, and a Biosphere Reserve. This review paper provides a broad overview of the climatic, hydraulic, biogeochemical features, bio-resources, and bio-productivity of the Lake. The interconnectivity between the different environmental components of the lake is presented, highlighting the main characteristics of this vital ecosystem. Its ecosystem consists of a permanent lake bordered by temporary marshes. It is …

Natural Language Processing For Disaster Tweets, Akinyemi D. Apampa, Nan Li

Publications and Research

Our goal is to establish an automatic model that identifies which tweets are about natural disasters based on the content of the tweets. Our method is to construct a decision tree based on keyword searching. We will construct the model using 7,645 tweets and test our model on 3,465 tweets as an assessment of the performance.

Development Of A Distributed International Patient Data Registry For Hairy Cell Leukemia, Leslie A Andritsos, Mirela Anghelina, Jasmine Neal, James S Blachly, Puneet Mathur, Omkar Lele, Claire Dearden, Sunil Iyengar, Matthew Cross, Clive S Zent, Kerry A Rogers, Narendranath Epperla, Gerard Lozanski, Christopher C Oakes, Eric Kraut, Amy S Ruppert, Qiuhong Zhao, Seema A Bhat, Francesco Forconi, Versha Banerji, Sasanka Handunnetti, Constantine S Tam, John F Seymour, Monica Else, Robert J Kreitman, Alan Saven, Timothy Call, Sameer A Parikh, Farhad Ravandi, James B Johnston, Enrico Tiacci, Xavier Troussard, Martin S Tallman, Sascha Dietrich, Tamar Tadmor, Alessandro Gozzetti, Pier Luigi Zinzani, Tadeusz Robak, Graeme Quest, Judit Demeter, Kanti Rai, Soledad A Fernandez, Michael Grever

Faculty, Staff and Student Publications

Hairy cell leukemia (HCL) is a rare lymphoproliferative disorder, comprising only 2% of all leukemias. The Hairy Cell Leukemia Foundation (HCLF) has developed a patient data registry to enable investigators to better study the clinical features, treatment outcomes, and complications of patients with HCL. This system utilizes a centralized registry architecture. Patients are enrolled at HCL Centers of Excellence (COE) or via a web-based portal. All data are de-identified, which reduces regulatory burden and increases opportunities for data access and re-use. To date, 579 patients have been enrolled in the registry. Efforts are underway to engage additional COE's to expand …

A Voice And Facial Recognition System To Protect Students From Being Forgotten Inside School Buses In The Kingdom Of Saudi Arabia, Ibrahim Alferaih

Theses and Dissertations

In this research, we discuss the situation of students in the three to eight year old age group. Every day in the Kingdom of Saudi Arabia during school days, more than 1,000,000 students are transported throughout the country by more than 15,000 school buses. Everything is dependent on the human element. During school transportation around the world, many children are forgotten inside the school bus and with many of them eventually going missing or even dying. The bus driver is usually busy and tired due to the focus on the road, which may make him lose focus on those on …

Mathematical Modeling Of Cancer Immunotherapy For Personalized Clinical Translation, Joseph D Butner, Prashant Dogra, Caroline Chung, Renata Pasqualini, Wadih Arap, John Lowengrub, Vittorio Cristini, Zhihui Wang

Faculty, Staff and Student Publications

Encouraging advances are being made in cancer immunotherapy modeling, especially in the key areas of developing personalized treatment strategies based on individual patient parameters, predicting treatment outcomes and optimizing immunotherapy synergy when used in combination with other treatment approaches. Here we present a focused review of the most recent mathematical modeling work on cancer immunotherapy with a focus on clinical translatability. It can be seen that this field is transitioning from pure basic science to applications that can make impactful differences in patients' lives. We discuss how researchers are integrating experimental and clinical data to fully inform models so that …

Chicago Alliance For Equity In Computer Science, Steven Mcgee, Lucia Dettori, Ronald I. Greenberg, Andrew M. Rasmussen, Dale F. Reed, Don Yanek

Computer Science: Faculty Publications and Other Works

Each year, about 14,000 Chicago Public Schools (CPS) students graduate with one year of high school computer science (CS) in fulfillment of the district’s CS graduation requirement. This accomplishment was the culmination of a decade of work by the Chicago Alliance for Equity in Computer Science (CAFÉCS), which includes CPS teachers and administrators, university CS faculty, and educational researchers. CAFÉCS research indicates that CPS significantly increased the capacity of schools to offer the Exploring Computer Science (ECS) introductory course, resulting in a rapid, equitable increase in students’ participation in CS. Making CS mandatory did not negatively impact performance in ECS. …

Soy Isoflavones Decrease Fibroglandular Breast Tissue Measured By Magnetic Resonance Imaging In Premenopausal Women: A 2-Year Randomized Double-Blind Placebo Controlled Clinical Trial, Lee-Jane W Lu, Nai-Wei Chen, Donald G Brunder, Fatima Nayeem, Manubai Nagamani, Thomas K Nishino, Karl E Anderson, Tuenchit Khamapirad

Faculty, Staff and Student Publications

BACKGROUND & AIMS: Populations consuming soy have reduced risk for breast cancer, but the mechanisms are unclear. We tested the hypothesis that soy isoflavones, which have ovarian hormone-like effects, can reduce fibroglandular breast tissue (FGBT, 'breast density'), a strong risk marker for breast cancer.

METHODS: Premenopausal women (age 30-42 years) were randomized to consume isoflavones (136.6 mg as aglycone equivalents, n = 99) or placebo (n = 98) for 5 days per week up to 2 years, and changes in breast composition measured by magnetic resonance imaging at baseline and yearly intervals were compared after square root transformation using linear …

Heterogeneous Nuclear Ribonucleoprotein K Is Overexpressed In Acute Myeloid Leukemia And Causes Myeloproliferation In Mice Via Altered, Marisa J L Aitken, Prerna Malaney, Xiaorui Zhang, Shelley M Herbrich, Lauren Chan, Oscar Benitez, Ashley G Rodriguez, Huaxian Ma, Rodrigo Jacamo, Ruizhi Duan, Todd M Link, Steven M Kornblau, Rashmi Kanagal-Shamanna, Carlos E Bueso-Ramos, Sean M Post

Faculty, Staff and Student Publications

Acute myeloid leukemia (AML) is driven by numerous molecular events that contribute to disease progression. Herein, we identify hnRNP K overexpression as a recurrent abnormality in AML that negatively correlates with patient survival. Overexpression of hnRNP K in murine fetal liver cells results in altered self-renewal and differentiation potential. Further, murine transplantation models reveal that hnRNP K overexpression results in myeloproliferation in vivo. Mechanistic studies expose a direct functional relationship between hnRNP K and RUNX1—a master transcriptional regulator of hematopoiesis often dysregulated in leukemia. Molecular analyses show that overexpression of hnRNP K results in an enrichment of an …

A Global Building Occupant Behavior Database, B Dong, Y Liu, W Mu

School of Art, Design and Architecture

This paper introduces a database of 34 field-measured building occupant behavior datasets collected from 15 countries and 39 institutions across 10 climatic zones covering various building types in both commercial and residential sectors. This is a comprehensive global database about building occupant behavior. The database includes occupancy patterns (i.e., presence and people count) and occupant behaviors (i.e., interactions with devices, equipment, and technical systems in buildings). Brick schema models were developed to represent sensor and room metadata information. The database is publicly available, and a website was created for the public to access, query, and download specific datasets or the …

Human Appropriation Of Net Primary Production Through Crops, Grazing, And Forestry In The U.S. From 1997 To 2012, Suman Paudel

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

This dissertation conducts a county-level analysis of human appropriation of net primary production (HANPP) harvested from crops, timber and grazing in the conterminous United States in the years 1997, 2002, 2007 and 2012. This study consists of three manuscripts (Chapters 2, 3, and 4). The first study quantifies net primary production in US counties in 1997, 2002, 2007 and 2012. The detailed HANPP study conducted concludes that HANPP is a valuable footprint tool for analyzing land use intensity and agricultural ecosystems. The second manuscript shows how HANPP is an improved or modernized ecological footprint and is a sustainable indicator as …

Graviweak Theory In Bicomformal Space, Mubarak Ukashat

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

There are four basic forces in nature: the electromagnetic force, which accounts for interactions of particles with charges; the weak force, which is responsible for radioactive decay; the strong force, which holds the particles inside a nucleus tightly bound together; and the gravitational force, which is responsible for keeping us on our beautiful planet, Earth and holding together our entire solar system. Physicists have been on the hunt for a theory that can single-handedly explain all these forces under the same underlying mathematical formulation. So far, physicists have suceeded in unifying the electromagnetic and weak forces in what is called …

Carbon Sinks And Sources In Great Salt Lake: Consequences Of Declining Lake Levels, Melissa Cobo Arias

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Globally, saline lakes are experiencing declining water level as a consequence of climate change, water diversions for human consumption, and management strategies that do not account for changing climate and drought conditions. Great Salt Lake (GSL) is a large saline lake in Utah, USA, and is, as most saline lakes, experiencing decreasing lake levels which may impact local carbon cycling. It is unknown how lakebed drying affects processes that control carbon sequestration and carbon emissions to the atmosphere. The goal of this research was to measure various biological processes that use, create, and transform carbon in GSL to understand the …

Power Approximations For Generalized Linear Mixed Models In R Using Steep Priors On Variance Components, Sydney Geisler

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

When designing an experiment, researchers often want to know how likely they are to detect statistically significant effects in the resulting data, i.e., they want to estimate their statistical power. The probability distribution method is a flexible way to do this, and it is currently implemented in the statistical software package SAS. This method requires a hypothetical data set (showing the magnitude of hypothesized effects) and constant values of variance components, which are critical elements of the statistical models used. The statistical software package R is increasingly popular, but the probability distribution method has not yet been implemented in R, …

Avian Species Distribution Models: Using Location Data To Inform Management Decisions, Marilyn E. Wright

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Both state and federal wildlife agencies strive to conserve and protect wildlife and their habitats as an important public resource. Applied management decisions often rely on being able to obtain data that can efficiently and effectively enhance the understanding of these systems for informing management actions. Wildlife managers often focus efforts on a small subset of species from an ecosystem, typically called focal species, who can serve as surrogates for understanding the health and function of the system. Models that consider how these focal species interact with the ecosystem are often used to better understand important aspects of their life …

Data Visualization, Dimensionality Reduction, And Data Alignment Via Manifold Learning, Andrés Felipe Duque Correa

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The high dimensionality of modern data introduces significant challenges in descriptive and exploratory data analysis. These challenges gave rise to extensive work on dimensionality reduction and manifold learning aiming to provide low dimensional representations that preserve or uncover intrinsic patterns and structures in the data. In this thesis, we expand the current literature in manifold learning developing two methods called DIG (Dynamical Information Geometry) and GRAE (Geometry Regularized Autoencoders). DIG is a method capable of finding low-dimensional representations of high-frequency multivariate time series data, especially suited for visualization. GRAE is a general framework which splices the well-established machinery from kernel …

Pleistocene Deposits Of Lower Wahweap Creek And Its Tributaries, Southern Utah, Noah Slade

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The famous landscapes of the Colorado Plateau have been created over millions of years, primarily by erosive forces of wind and water. Interruptions in the long-term erosion of the landscape occur when streams gain more sediment than they can transport, which causes deposition along channels and floodplains. The resulting sequences of terrace deposits are used by geologists to study when and how river systems have evolved.

Mammoth bones were recently discovered in stream deposits along Wahweap Creek, a tributary of the Colorado River in southern Utah. Previous work indicates that the deposits pre-date the last ice age, making it one …

Investigations Of Prokaryotic Defense Systems, Hannah Domgaard

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Bacteria are constantly threatened with infection by mobile genetic elements (MGE) such as bacteriophage and plasmids. Bacteriophage and plasmids require the bacteria's cellular infrastructure to replicate their genomes. Rampant replication can lead to cell death which is one reason why bacteria have developed a diverse array of immune systems to prevent or limit infection. This thesis studies three types of bacterial immune systems, type IV-A CRISPR-Cas (Clustered Regularly Interspaced Short Palindromic Repeat –CRISPR associated), type V-A2 CRISPR-Cas systems, and Wadjet systems.

The type IV-A system lies adjacent to a dinG-like helicase gene. Research has shown that this system can target …

Modeling And Control Of Battery Management Systems With High-Frequency Ac Link Coupled Multiport Series Resonant Converters For 2nd Life Battery Applications, Brooks Jace Maughan

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

While the use and production of Electric Vehicles becomes more prevalent, it is also important to make this economical and ensure the reduction of a carbon footprint. Second-life batteries can satisfy both problems as batteries can be used in a second-life application for lower power purposes such as supplementing the grid so the infrastructure needed to charge the expanding fleet of Electric Vehicles can be easily supplied. This thesis goes through the process of Active Cell Balancing which will produce equal capacities, or similar batteries, that can be more efficiently used in these and other types of second-life applications. The …

Development Of In Situ Second-Order Nonlinear Optical Scatterings For Molecular Behaviors At Aerosol Surfaces, Yuqin Qian

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Aerosol particles are one of the most important components of the atmosphere. During the growth of aerosol particles, they directly or indirectly affect air quality, human health, and environmental chemistry. Therefore, understanding the chemical and physical properties of such particles is an important scientific, engineering, and medical issue. The growth of aerosol particles in the atmosphere is closely related to the chemical structure at its surface, as well as the heterogeneous reactions which take place at and below the particle’s surface. However, there is a lack of suitable surface-specific analytical techniques which directly measure the chemical structure of aerosol particle …

Old-Growth Forest Dynamics After Fire And Drought In The Sierra Nevada, California, Usa, Kendall M.L. Becker

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Understanding forest ecosystems is important because forests cover approximately one-third of Earth’s land area, store half of Earth’s carbon, shelter half of Earth’s species, and absorb a quarter of new anthropogenic carbon emissions, slowing climate change. This dissertation provides insight into future forest habitat, fuels, species composition, and structure by investigating what happens to snags, seedlings, and trees in an old-growth forest after a low- to moderate-severity fire.

Chapter II explores how low- to moderate-severity fire changes snag fall rates. Predicting how long snags will remain standing after fire is essential for managing habitat, understanding chemical cycling in forests, and …

Serendipity Shape Function For Hybrid Fluid/Kinetic-Pic Simulations, Trevor V. Taylor

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The Sun in our solar system and stars are capable of generating enormous amounts of energy. The process by which these gaseous, celestial bodies are able to produce such large amounts of energy is called thermonuclear fusion. Fusion happens when particles collide with one another at energy levels high enough to overcome the Coulomb force and then release vast amounts of energy. Plasma, the fourth state of matter, is the natural state of stars. Plasma is an ionized gas that consists of negatively and positively charged particles. Stars, which have immense mass, can confine the plasma through their gravity to …

Late Pleistocene Piedmont Records In The Grand Staircase Region, Southern Utah, Alexander K. Short

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Today the climate in the southwestern United States is arid, characterized by desert landscapes and habitats, periods of drought, and arroyo streams that frequently fill with, and erode, through fine riverbed sediments. A series of cliffs and benches rising from the Grand Canyon to the southern plateaus of Utah, known as the Grand Staircase - home to Kodachrome Basin State Park, Bryce Canyon, are a classical example of this environment as we know it today. However, a record spanning the past 300 thousand years is preserved on the steps of the staircase indicating periods in the past where the climate …

Design Of Environment Aware Planning Heuristics For Complex Navigation Objectives, Carter D. Bailey

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

A heuristic is the simplified approximations that helps guide a planner in deducing the best way to move forward. Heuristics are valued in many modern AI algorithms and decision-making architectures due to their ability to drastically reduce computation time. Particularly in robotics, path planning heuristics are widely leveraged to aid in navigation and exploration. As the robotic platform explores and navigates, information about the world can and should be used to augment and update the heuristic to guide solutions. Complex heuristics that can account for environmental factors, robot capabilities, and desired actions provide optimal results with little wasted exploration, but …

Bedrock Geology Map Of The Naomi Peak 7.5' Quadangle, Cache County, Utah And Novel Age Constraints On Its Cambrian Strata, Hannah R. Cothren

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Geologists use various “rock-clocks” in order to interpret the timing and tempo of events in Earth’s history. These include global geochemical events in the oceans (chemostratigraphy), the evolution of certain fossil species (trilobite biostratigraphy), and the radiogenic decay of uranium to lead in certain mineral such as zircon (U-Pb geochronology). Integrating these methods in the stratigraphic record in one location can provide a well-constrained timeline for a select part of the Geologic, or Deep Time, record. This technique is especially important in the Cambrian Period (538.8 to 486.9 million years; Ma), which sets the stage for life today with the …

Functional Characterization Of The Newly Discovered Type V Crispr-Cas Protein Cas12a2, Dylan J. Keiser

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Similarly to people, bacteria are under the treat of infection by viruses. To circumvent these threats, bacteria evolve complex immune systems. Our understanding of some of these immune systems has led to many advancements in the field of Biotechnology including tools that made expressing proteins for study in a lab easier, tools that revolutionized the feasibility of gene editing, and tools that could change the way we think about viral diagnostics and cancer therapeutics. A certain type of immune system that bacteria use to fight virus is called a CRISPR system. Presented here is work to understand the function of …

Normative Evaluations Of Resource Conditions: The Influence Of Visitor Characteristics And Implications For Recreation Management In Urban-Proximate Parks, Jordan E. Nesbitt

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Urban-proximate parks and protected areas provide a unique recreation landscape to individuals living in and near urban centers. They have been shown to provide similar recreation experiences to traditionally studied parks and protected areas such as National Parks, National Forests and Wilderness areas. This study takes place in a set of four urban-proximate parks in Orange County, California, USA. These parks are designated as urban-proximate because they are located within 100 miles of an urban center with 1 million or more people. Using norm theory, a well vetted social science theory, this work sought to identify thresholds of acceptability for …

Investigating The Use Of Quartz Luminescence And Rock-Color Alteration To Characterize Wildfire Exposure; Applied To The 2020 Mangum Fire, Kaibab Plateau, Arizona, April I. Phinney

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Wildfires appear to be increasing in size, severity, and frequency. Land managers need information on past wildfire behavior to make effective and adaptive land management plans. However, there are only a few techniques and data sources that provide information on past fire heating. This study aims to provide new methods to equip managers with a more robust understanding of historic and modern fire behavior. Fire behavior is assessed using novel methods that can assess soil and rock response to past wildfire heat exposure.

This study examined samples from the 2020 Mangum Fire, in northern Arizona. Sediment and rock were gathered …

A Theoretical Trade-Off Between Wave Drag And Sonic Boom Loudness Due To Equivalent Area Changes On A Supersonic Body, Nolan L. Dixon

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The NASA University Leadership Initiative (ULI) titled ”Adaptive Aerostructures for Revolutionary Civil Supersonic Transportation” consists of a team of university and industry partners studying the feasibility of reducing the perceived loudness of the sonic boom by introducing an adaptive geometry at localized regions of an aircraft’s outer-mold line. The Utah State University AeroLab is a member of this ULI team and has produced low-fidelity tools to predict the aerodynamic and boom loudness effects from localized changes to the geometry.

Such changes to the geometry affect both the sonic boom loudness and wave drag; however, the precise relationship between boom loudness …

Relativistic, Continuum Drift-Kinetic Capability In The Nimrod Plasma Fluid Code, Tyler Markham

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

A ”runaway” electron is an electron that, through a self-reinforcing process, accelerates to relativistic speeds. At multiple points during tokamak discharges, relativistic runaway electron (RE) beams can form. RE beams pose a serious risk in the form of severe damage to plasma facing components in ITER and future burning plasma reactors. Early RE studies used simplified geometric and transport models, but enabled feedback on the overall plasma evolution. This feedback is important for understanding the evolution of the RE current column. The work in this thesis is an important step toward self-consistently evolving an RE distribution in the plasma fluid …

A Novel Computational Method To Compute Rock Scour Due To Dam Overtopping, Erik F. R. Bollaert

Protections Conference

Flood events generating potential risk for dam overtopping may become more frequently in the future, especially because of increasing climate change. Crest overflows at arch dams generally impact the downstream rock mass very close to the dam foundation. As such, any scour of the rock mass generated by this phenomenon may potentially endanger the stability of the dam and its appurtenant structures. Hence, pertinent assessment of this scour formation through space and time is becoming increasingly relevant to dam safety. This paper presents a novel computational method for detachment of prismatic rock blocks from their mass when impacted by high-velocity …