Digital Commons Network^™

Asking The Question ‘What Matters To You?’ In A London Intensive Care Unit, Harriet Pittaway, Laura White, Karen Turner, Angelique Mcgillivary

Journal of Patient-Centered Research and Reviews

Purpose: At the heart of the paradigm shift in approach to patient care from paternalism toward shared decision-making lies the international “What Matters To You?” (WMTY) movement. However, WMTY principles are not frequently applied to the critical care setting. The aim of this quality improvement project work was to design and integrate a tool for all patients admitted to the intensive care unit (ICU) that helped answer WMTY.

Methods: Using Plan-Do-Study-Act (PDSA) methodology across 8 cycles, a multidisciplinary team designed and integrated a bedside poster into the ICU. Quantitative and qualitative data were collected via a bedside audit process on …

Real-World Third Covid-19 Vaccine Dosing And Antibody Response In Patients With Hematologic Malignancies, Michael A. Thompson, Sigrun Hallmeyer, Veronica E. Fitzpatrick, Yunqi Liao, Michael P. Mullane, Stephen C. Medlin, Kenneth Copeland, James L. Weese

Journal of Patient-Centered Research and Reviews

Purpose: This study sought to describe the changes in immune response to a third dose of either Pfizer’s or Moderna’s COVID-19 mRNA vaccine (3V) among patients with hematologic malignancies, as well as associated characteristics

Methods: This retrospective cohort study analyzed pre-3V and post-3V data on 493 patients diagnosed with hematologic malignancies across a large Midwestern health system between August 28, 2021, and November 1, 2021. For antibody testing, S1 spike antigen of the SARS-CoV-2 virus titer was used to determine serostatus.

Results: Among 493 participants, 274 (55.6%) were seropositive both pre- and post-3V (+/+) while 115 (23.3%) seroconverted to positive …

Community-Based Asthma Assessment In Young Children: Adaptations For A Multicentre Longitudinal Study In South Asia, Mohammad Shahidul Islam, Samin Huq, Steven Cunningham, Jurgen Schwarze, Asmd Ashraful Islam, Mashal Amin, Farrukh Raza, Benazir Baloch, Muhammad Imran Nisar, Sajid Bashir Soofi

Department of Paediatrics and Child Health

Background: Systematic assessment of childhood asthma is challenging in low- and middle-income country (LMIC) settings due to the lack of standardised and validated methodologies. We describe the contextual challenges and adaptation strategies in the implementation of a community-based asthma assessment in four resource-constrained settings in Bangladesh, India, and Pakistan.
Method: We followed a group of children of age 6-8 years for 12 months to record their respiratory health outcomes. The study participants were enrolled at four study sites of the 'Aetiology of Neonatal Infection in South Asia (ANISA)' study. We standardised the research methods for the sites, trained field staff …

Is Omicron The Game Changer Of Covid-19 Infection In Children?, Qiwei Liang, Xiuping Zhang, Scott Lowe, Yaru Li, Rachel Bentley, Bethany King, John Patrick Nanola Uy, Chenyu Sun

Student Publications

No abstract provided.

Gis Automated Delineation And Analysis Of Cancer Service Areas In The United States, Changzhen Wang

LSU Doctoral Dissertations

Delineating a meaningful and reliable geographic unit pertaining to cancer care is essential in examining geographic variations in cancer care for better analysis, management, and planning. Public health researchers have devoted great efforts to defining various service areas, which; however, lack scientific rigor or are unrepresentative of the highly specialized cancer care markets, and their methods have become obsolete in the era of big data and high geo-computation. This study develops the “Spatially Constrained Leiden (ScLeiden)” method, a network community detection algorithm in Geographic Information Systems (GIS), and applies it to delineate a series of coherent cancer service …

Clinical And Occupational Risk Factors For Coronavirus Disease 2019 (Covid-19) In Healthcare Personnel, Jennie H. Kwon, Philip J. Budge, Caroline A. O'Neil, Kate Peacock, Eva M. Aagaard, Victoria J. Fraser, Margaret A. Olsen, Hilary Babcock

2020-Current year OA Pubs

No abstract provided.

Reducing The Incidence Of Clabsi Through Hand Hygiene, Bindu Paudel

Student Scholarly Projects

Practice Problem: Central line-associated bloodstream infections (CLABSI) account for most hospital-associated preventable infections in the United States and globally. Implementation of effective hand hygiene practices is considered to be highly effective in preventing CLABSIs if performed during insertion and every handling instance.

PICOT: The PICOT question guiding this project is as follows: Among intensive care unit employees (P), implementation of hand hygiene awareness program and practice (I) compared to current practices (C) in reducing CLABSI incidences (O) among adult inpatients in 10 weeks (T)?

Evidence: The evidence from a rigorous literature review showed that the appropriate education …

2022-07-16_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus/stats/coronavirus-symptoms. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated twice a week on Mondays and Thursdays.

Syndromic Surveillance System data is obtained from approximately 216 facilities participating in syndromic surveillance (139 Emergency Departments (ED), 77 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, …

Amplification Of Black Vulture (Coragyps Atratus) Dna From Regurgitated Food Pellets, Daniel R. Taylor, Bryan M. Kluever, John S. Humphrey, Iona M. Hennessy, Amber Sutton, William E. Bruce, Antoinette J. Piaggio

United States Department of Agriculture Wildlife Services: Staff Publications

Studies that rely on noninvasive collection of DNA for birds often use feces or feathers. Some birds, such as vultures, regurgitate undigested matter in the form of pellets that are commonly found under roost sites. Our research demonstrates that regurgitated pellets are a viable, noninvasive source of DNA for molecular ecology studies of vultures. Our objectives were to amplify 5 microsatellite loci designed for distinguishing Turkey Vultures (Cathartes aura) and Black Vultures (Coragyps atratus) in a single, multiplexed PCR, and to determine how long the target nuclear DNA persists after a vulture pellet is regurgitated and …

Association Between Primary Care Provider Status And Preventive Health Care Among People Who Inject Drugs, E Katherine Nenninger, Katherine Sharp, Bianca Bustamente, Kim Murray, Kinna Thakarar

Journal of Maine Medical Center

Introduction: People who inject drugs (PWID) are at increased risk for preventable, communicable infections, such as hepatitis B. Preventive care, such as hepatitis B vaccination, is often delivered through primary care providers (PCPs). However, PWID may not have access to PCPs and, therefore, may receive preventive care through other sites. We aimed to characterize PCP and preventive care use among PWID in Maine.

Methods: This is a cross-sectional study of PWID hospitalized with infections associated with injection drug use in Maine from January 2019 to May 2020. Descriptive analyses were used to identify characteristics of participants, rates of screening, and …

Occupational Therapists’ Perspectives During The Covid-19 Pandemic, Emily N. Maas, Allison Sullivan, Said Nafai, James Plummer

The Open Journal of Occupational Therapy

On March 11, 2020, the World Health Organization declared the outbreak of the coronavirus disease 2019 (COVID-19) as a global pandemic. Hospitals, nursing homes, and communities worldwide were flooded with patients diagnosed with COVID-19, resulting in the increased need for medical care and treatment by health care professionals, such as occupational therapists. This study analyzes output from a quantitative online survey design, which was created on SurveyMonkey and included 43 questions. Data from the survey were collected, categorized, and measured through the SurveyMonkey computer system and included information gathered from 204 occupational therapists from October 2020 to February 2020. Based …

Work Environment: Leadership, Communication, And Autonomy. The Perception Of Work Among Polish Employees During Turbulent Time Of Covid-19 Pandemic, Monika Sady, Piotr Sedlak

European Management Studies

Purpose: The article focuses on the assessment of knowledge workers’ relation with superiors, internal communication, perceived autonomy and feeling of appreciation. The goal of the article is also to extend current knowledge of the perception of cooperation between employees. The authors were able to identify interdependencies among the researched variables and the impact of COVID-19 on peoples’ professional situation. Design/methodology/approach: The article presents the results of a CAWI survey conducted on a large sample of 2778 specialists and managers in Poland. The researchers used the purposive sampling method to reach the population of white-collar workers who experienced remote work or …

Holy Cross Magazine Vol. 56, No. 3, Summer 2022, College Of The Holy Cross

Holy Cross Magazine

Integrated Science Complex Named for Anthony Fauci, M.D., ’62, Hon. ’87
Returning for his 60th reunion, the nation’s public health leader reflected on the impact of his Holy Cross education.
By Michael Bonner

Worcester Black History Trail Opens as Community Lauds Holy Cross Faculty Member
Senior lecturer Thomas Doughton credited as one of the sparks that led to its long-anticipated creation and debut.
By Michael Bonner

New Whall Chair Will Continue Fostering Lifelong Student-Faculty Bonds
$2.6 million gift establishes Helen M. Whall Chair in Race, Gender and Social Justice and a biannual Shakespeare lecture series.
By Michael Bonner

The Jesuits …

Monkeypox: What You Need To Know, Adam Pope

Browse All News

No abstract provided.

The Impact Of The Covid-19 Pandemic On The Global Risk Landscape In The Era Of Smart World, Sylwia Bąk, Piotr Jedynak

European Management Studies

Purpose: The purpose of this paper is to identify the impact of the COVID-19 pandemic on the trend of changes in the landscape of global risks together with the implications of these changes for management in the SMART WORLD era. Design/methodology/approach: The research process was based on the triangulation of research methods. The main research method used was the analysis of the World Economic Forum’s “The Global Risks Reports” for the years 2018–2021. The other method used in the research were a comparative analysis and selected quantitative tools. Findings: The conducted empirical research allowed the authors: 1) to show the …

Pneumonitis After Immune Checkpoint Inhibitor Therapies In Patients With Acute Myeloid Leukemia: A Retrospective Cohort Study, Ajay Sheshadri, Alberto A Goizueta, Vickie R Shannon, David London, Guillermo Garcia-Manero, Hagop M Kantarjian, Farhad Ravandi-Kashani, Tapan M Kadia, Marina Y Konopleva, Courtney D Dinardo, Sherry Pierce, Abdulrazzak Zarifa, Aya A Albittar, Linda L Zhong, Fechukwu O Akhmedzhanov, Muhammad H Arain, Mansour Alfayez, Ahmad Alotaibi, Mehmet Altan, Aung Naing, Tito R Mendoza, Myrna C B Godoy, Girish Shroff, Sang T Kim, Saadia A Faiz, Dimitrios P Kontoyiannis, Fareed Khawaja, Kristofer Jennings, Naval G Daver

Faculty, Staff and Student Publications

Background: Immune checkpoint inhibitors (ICI), combined with hypomethylating agents, can be used to treat acute myeloid leukemia (AML), but this strategy results in a high rate of pneumonitis. The authors sought to determine risk factors for pneumonitis development and whether pneumonitis increased mortality.

Methods: The authors conducted a retrospective review of 258 AML patients who received ICI-containing regimens from 2016 to 2018. A multidisciplinary adjudication committee diagnosed pneumonia and pneumonitis by reviewing symptoms, imaging, microbiology, and response to therapies. To measure risk factors for pneumonitis and mortality, multivariate Cox proportional hazards models were constructed. Pneumonia, pneumonitis, and disease progression were …

Back Cover Vol 4 Issue 1

Graduate Medical Education Research Journal

No abstract provided.

Introducer-Free Mis-Assisted Ventriculoperitoneal Shunt Placement: A Technical Document, Eric Chen, Patrick Opperman, Edson Deoliveira, Priscila Rodrigues Armijo, Vishal Kothari, Daniel Surdell

Graduate Medical Education Research Journal

Background

The placement of the distal catheter of a ventriculoperitoneal shunt (VPS) can be challenging in patients with a large body habitus. Given the complications associated with ventriculoperitoneal shunts and known infection risk of obese patients, new techniques for VPS placement that bypass the abdominal fat must be sought. By avoiding the abdominal fat, decreased complications and infection risk may be possible.

Objective

The objective of this technical document is to describe a laparoscopic approach to the abdominal cavity during ventriculoperitoneal shunt surgery that makes use of a direct tunneling technique into the peritoneal space.

Methods

We perform a ventriculoperitoneal …

Scholarly Activity In Residency: A Needs Assessment Of Challenges And Proposed Solutions, Jonathan Hall, Jana L. Wardian Phd, Jasmine R. Marcelin

Graduate Medical Education Research Journal

Introduction

Resident physician participation in scholarly activity is associated with significant benefits ranging from trainees’ personal development to improved quality of patient care. Residency programs have taken varied approaches to improve resident engagement in scholarship, though interventions have demonstrated mixed results regarding objective measures of scholarly productivity. Concerns regarding waining interest in scholarship amongst internal medicine residents prompted a department-wide needs assessment to evaluate opportunities for scholarship and challenges preventing resident participation.

Methods

A web-based survey was developed and distributed to Department of Internal Medicine faculty and residents at the PGY2 level or higher and recent graduates within the last …

Review Of The Cloacininae Stossich (Nemata: Strongyloidea) From Australasian Marsupials (Marsupialia: Macropodoidea), Ian Beveridge, Lesley R. Smales

MANTER: Journal of Parasite Biodiversity

The nematode sub-family Cloacininae from Australasian macropodoid marsupials is reviewed. Keys are provided to all genera and species currently known. A revised definition of the sub-family and detailed generic diagnoses are provided. For each species, full synonymies and literature citations are included along with known hosts, geographical distributions and associated DNA sequence data. A brief morphological synopsis of each species is provided together with illustrations of the morphological features needed for identification using the keys. Due to uncertainties relating to the division of the sub-family into tribes, only the nominal allocation to tribe is provided. Two new genera are erected, …

Racial Disparities In Hepatitis B Birth Dose In The Washington Metropolitan Region, 2018-2020., Hee-Soon Juon, Donna T Sheler, Jane Pan, Daisy Le, Y Tony Yang

Department of Medical Oncology Faculty Papers

Hepatitis B vaccination protects newborns from contracting the hepatitis B virus that may lead to chronic infection, liver failure, or death. Trends and racial differences in the administration of the hepatitis B (HepB) birth dose in 2018-2020 were examined in the targeted region. A retrospective analysis of electronic birth dose vaccination data of newborns in 2018-2020 was performed. Birth data from six birthing facilities and home delivery records were obtained from the DC Health Department Vital Statistics Division. This data represented 40,269 newborns and included the mother's race and ethnicity, health insurance type, birthing facility, and administration of the HepB …

Digital Contact Tracing And Privacy, Mahdi Nasereddin, Edward J. Glantz, Galen A. Grimes, Joanne Peca, Michelle Gordon, Mike Bartolacci

Journal of Cybersecurity Education, Research and Practice

Digital contact tracing tools were developed to decrease the spread of COVID-19 by supplementing traditional manual methods. Although these tools have great potential, they were developed rather quickly resulting in tools with varying levels of success. The main issues with these tools are over privacy and who might have access to the information gathered. In general, their effectiveness varied globally, where users expressed privacy concerns associated with sharing identity, illness, and location information. This paper reviews these issues in deployments across Asia, Europe, and the United States. The goal is to begin a discussion that improves the design and development …

Deliberate Transmission Of Infectious Diseases, Jamal Zaid Al-Kilani, Mahmoud Dhiab

An-Najah University Journal for Research - B (Humanities)

In This research, entitled (deliberate transmission of infectious diseases). we talked about the concept of infectious diseases and their seriousness in weakening the immune system of the body, the types of these infectious diseases, the organisms causing them, and the role of Islam and its approach in taking preventive measures to prevent the transmission of diseases. We have also tackled the jurists' verification of infection, ways of transmission and the judgement on intention concerning who deliberately intends to transmit infection to an identical person or whole community. Consequently, whenever the infection is fatal which embodied in the scope of deliberately …

Study Characterizes Pediatric Hepatitis Outbreak Cluster In Alabama, Hannah Echols

Browse All News

No abstract provided.

Three Dimensions Of Covid-19 Risk Perceptions And Their Socioeconomic Correlates In The United States: A Social Media Analysis, Shan Qiao Ph.D., Zhenlong Li Ph.D., Chen Liang Ph.D., Xiaoming Li Ph.D., Caroline Rudisill Ph.D.

Faculty Publications

Social media analysis provides an alternate approach to monitoring and understanding risk perceptions regarding COVID-19 over time. Our current understandings of risk perceptions regarding COVID-19 do not disentangle the three dimensions of risk perceptions (perceived susceptibility, perceived severity, and negative emotion) as the pandemic has evolved. Data are also limited regarding the impact of social determinants of health (SDOH) on COVID-19-related risk perceptions over time. To address these knowledge gaps, we extracted tweets regarding COVID-19-related risk perceptions and developed indicators for the three dimensions of risk perceptions based on over502 million geotagged tweets posted by over 4.9 million Twitter users …

Three Dimensions Of Covid-19 Risk Perceptions And Their Socioeconomic Correlates In The United States: A Social Media Analysis, Shan Qiao, Zhenlong Li, Caroline Rudsill

Faculty Publications

Social media analysis provides an alternate approach to monitoring and understanding risk perceptions regarding COVID-19 over time. Our current understandings of risk perceptions regarding COVID-19 do not disentangle the three dimensions of risk perceptions (perceived susceptibility, perceived severity, and negative emotion) as the pandemic has evolved. Data are also limited regarding the impact of social determinants of health (SDOH) on COVID-19-related risk perceptions over time. To address these knowledge gaps, we extracted tweets regarding COVID-19-related risk perceptions and developed indicators for the three dimensions of risk perceptions based on over 502 million geotagged tweets posted by over 4.9 million Twitter …

The Testis-Specific E3 Ubiquitin Ligase Rnf133 Is Required For Fecundity In Mice, Kaori Nozawa, Yoshitaka Fujihara, Darius J Devlin, Ricardo E Deras, Katarzyna Kent, Irina V Larina, Kohei Umezu, Zhifeng Yu, Courtney M Sutton, Qiuji Ye, Laura K Dean, Chihiro Emori, Masahito Ikawa, Thomas X Garcia, Martin M Matzuk

Faculty, Staff and Students Publications

BACKGROUND: Ubiquitination is a post-translational modification required for a number of physiological functions regulating protein homeostasis, such as protein degradation. The endoplasmic reticulum (ER) quality control system recognizes and degrades proteins no longer needed in the ER through the ubiquitin-proteasome pathway. E2 and E3 enzymes containing a transmembrane domain have been shown to function in ER quality control. The ER transmembrane protein UBE2J1 is a E2 ubiquitin-conjugating enzyme reported to be essential for spermiogenesis at the elongating spermatid stage. Spermatids from Ube2j1 KO male mice are believed to have defects in the dislocation step of ER quality control. However, associated …

Evaluasi Sistem Informasi Surveilans Malaria (Sismal) Di Wilayah Kerja Dinas Kesehatan Kota Malang, Muhammad Irvan Indrayana, Iwan Ariawan

Jurnal Biostatistik, Kependudukan, dan Informatika Kesehatan

Malaria merupakan salah satu penyakit menular yang memiliki potensi tinggi dalam penyebarluasan penyakit. Berdasarkan dari Badan Pusat Statistik, Jawa Timur memiliki 7.256 kasus malaria suspek dan di kota Malang memiliki 11 kasus suspek pada tahun 2020 dan mayoritas berasal dari kasus impor dimana pasien berasal atau pernah melakukan perjalanan di luar wilayah Kota Malang yang kemudian merasakan gejala dan melakukan pemeriksaan di Kota Malang. Sistem Informasi Surveilans Malaria (SISMAL) adalah instrumen guna melakukan kegiatan pencatatan, pelaporan dan untuk meningkatkan validitas dan kelengkapan dalam pelaporan data malaria yang merupakan salah satu hal penting untuk mendukung terselenggaranya sistem Surveilans yang baik. Sistem …

Newborn Weight Change And Predictors Of Underweight In The Neonatal Period In Guinea-Bissau, Nepal, Pakistan And Uganda, Valerie J. Flaherman, Amy S. Ginsburg, Muhammad Imran Nisar, Muddassir Altaf, Khushboo Liaquat, Benazir Baloch, Najeeb Rehman, Yasir Shafiq, Shabina Ariff, Fyezah Jehan

Department of Paediatrics and Child Health

In low- and middle-income countries (LMIC), growth impairment is common; however, the trajectory of growth over the course of the first month has not been well characterised. To describe newborn growth trajectory and predictors of growth impairment, we assessed growth frequently over the first 30 days among infants born ≥2000 g in Guinea-Bissau, Nepal, Pakistan and Uganda. In this cohort of 741 infants, the mean birth weight was 3036 ± 424 g. For 721 (98%) infants, weight loss occurred for a median of 2 days (interquartile range, 1-4) following birth until weight nadir was reached 5.9 ± 4.3% below birth …

Outcomes For Patients With Severe Chronic Neutropenia Treated With Granulocyte Colony-Stimulating Factor, David C Dale, Audrey Anna Bolyard, James A Shannon, James A Connelly, Daniel C Link, Mary Ann Bonilla, Peter E Newburger

2020-Current year OA Pubs

Severe chronic neutropenia (SCN), defined as blood neutrophils <0.5 × 109/L for >3 months, is an uncommon hematological condition associated with recurrent and severe bacterial infections. After short-term clinical trials showed the benefits of granulocyte colony-stimulating factor (G-CSF) treatment for SCN, SCNIR (Severe Chronic Neutropenia International Registry) opened to determine the long-term benefits and safety of this treatment. This report summarizes findings from more than 16 000 patient-years of prospective observations for patients with congenital and acquired SCN. We observed that adverse outcomes depend on the underlying etiology. Myelodysplasia (MDS) and acute myeloid leukemia (AML) occur infrequently and largely in patients with congenital neutropenias. …