Digital Commons Network^™

Metabolomics Reveal Size-Dependent Impacts Of Cerium Oxide Nanoparticles On Grains Of Barley (Hordeum Vulgare L.), Naum Jepkemei Kirwa

Graduate Theses/Dissertations

Plants are exposed to emerging contaminants including nanoparticles, due to the novel but wide uses of these materials. However, researchers have shown contradicting effects of CeO₂-NPs on barley grains with focus mostly on concentration effects and not sizes of these CeO₂-NPs. Therefore, this study aimed at comparing the effects of 0nm (control), 8nm, and 40nm (250 mg CeO₂-NPs/kg soil) on the metabolite profile of barley grains. GC-FID and GC-QTOF-MS were used to measure fatty acid contents and metabolomic changes respectively. GC-FID analysis revealed that palmitic acid, oleic acid, linoleic acid, and the total fatty …

How Exercise Affects The Musculoskeletal System In The Biological Sexes: A Literature Review, Lauren Connolly

Honors Program Theses

Exercise has countless benefits for the human body. Physical activity increases overall health and reduces the risk of developing many chronic diseases. While the entire body is impacted by exercise, the musculoskeletal system is perhaps targeted most directly. Muscle contraction is required to complete any form of exercise, which helps build muscle mass and consequently strengthens bones. The physiology of musculoskeletal growth after exercise is the same for all individuals. However, the magnitude of this growth is not the same for men and women. Men have a profound ability to gain muscle mass that most women are not capable of …

Near-Infrared Spectroscopy Estimation Of Combined Skeletal Muscle Oxidative Capacity And O2 Diffusion Capacity In Humans, Andrea M. Pilotto, Alessandra Adami, Raffaele Mazzolari, Lorenza Brocca, Emanuela Crea, Lucrezia Zuccarelli, Maria A. Pellegrino, Roberto Bottinelli, Bruno Grassi, Harry B. Rossiter, Simone Porcelli

Kinesiology Faculty Publications

The final steps of the O2 cascade during exercise depend on the product of the microvascular-tointramyocyte PO2 difference and muscle O2 diffusing capacity (DmO2). Non-invasive methods to determine DmO2 in humans are currently unavailable. Muscle oxygen uptake (mVO2) recovery rate constant (k), measured by near-infrared spectroscopy (NIRS) using intermittent arterial occlusions, is associated with muscle oxidative capacity in vivo. We reasoned that k would be limited by DmO2 when muscle oxygenation is low (kLOW), and hypothesized that: i) k in well-oxygenated muscle (kHIGH) is associated with maximal O2 flux in fiber bundles; and ii) Δk (kHIGH-kLOW) is associated with capillary …

The Columns, 1983 Spring

The Columns

Cover Story, "Something To Cheer About!"

The MSU Varsity Spirit Squad captured first place at the 1983 Collegiate Cheerleader National Championship competition held in Dallas in January by the National Cheerleader Association, thereby gaining the status of the No. 1 cheerleading squad in the country.

Also featured, "MSU First in Nation to offer Degree in Bio-Medical Illustration"

Memphis State, in cooperation with the University of Tennessee Center for the Health Sciences, now offers a bachelor of professional studies degree in biomedical illustration, enabling people to learn how to communicate and document the life sciences through art and photography. The new …

Stroboscopic Augmented Reality As An Approach To Mitigate Gravitational Transition Effects During Interplanetary Spaceflight, Ethan Waisberg, Joshua Ong, Nasif Zaman, Sharif Amit Kamran, Andrew G. Lee, Alireza Tavakkoli

International Journal of Aviation, Aeronautics, and Aerospace

During interplanetary spaceflight, periods of extreme gravitational transitions will occur such as transitions between hypergravity, hypogravity, and microgravity. Following gravitational transitions, rapid sensorimotor adaptation or maladaptation may occur which can affect gaze control and weaken dynamic visual acuity in astronauts. A reduction in dynamic visual acuity during spaceflight could possibly impact or impair mission critical activities (e.g., control of extraterrestrial machinery/vehicles and other important tasks). Stroboscopic visual training is an emerging visual tool that has been terrestrially observed to enhance visual performance and perception by performing tasks under conditions of intermittent vision. This technique has also been seen to increase …

2022-2023 Course Catalog, University Of Montana--Missoula. Office Of The Registrar

University of Montana Course Catalogs, 1895-2024

An annual catalog of courses and course descriptions offered at the University of Montana.

Lighting The Way: 2021-22 Report Of The President, Office Of The President, Gonzaga University

Office of the President Publications

Each year, Gonzaga University's Office of the President produces an annual Report of the President. This publication that highlights just a few of the many accomplishments over the previous academic year, and is intended to convey gratitude to our Trustees and Regents, benefactors, and many supporters.

Cds Major, Cds

Program Revisions/Additions

No abstract provided.

The Role Of Ovarian Hormones In Appetite-Regulation: Examining The Post-Exercise Appetite Response In Pre- Vs Post-Menopausal Females, Jessica A.L. Tucker

Theses and Dissertations (Comprehensive)

INTRODUCTION: Appetite fluctuates across the menstrual cycle, suggesting ovarian hormones are involved in the regulation of appetite hormones and energy intake. Exercise is another regulator of appetite with higher intensity exercise generating a greater and more consistent suppression. Considering there is limited evidence investigating the role of ovarian hormones in appetite regulation, menopause represents a stage of life where ovarian function declines, thus providing an opportunity to further explore the role of ovarian hormones in the appetite-regulatory response to exercise. PURPOSE: To examine the role of ovarian hormones on appetite-regulating hormones in pre- and post-menopausal females following a …

Biom 3110: Medical Physiology (Syllabus), Bradford D. Pendley

Biomedical Engineering Syllabi Archive

Course Description: Basic principles of human physiology and how these are applied in medicine and biomedical engineering problem and devices; physiological principles using appropriate mathematical and engineering models to construct an understanding of how the body works as an integrated system.

Biom 3110(Honors): Medical Physiology (Syllabus), Bradford D. Pendley

Biomedical Engineering Syllabi Archive

Course Description: Basic principles of human physiology and how these are applied in medicine and biomedical engineering problem and devices; physiological principles using appropriate mathematical and engineering models to construct an understanding of how the body works as an integrated system.

Factors Contributing To College Counselors’ Probability To Take A Client’S Sexual History, Adam Gregory

Graduate Research Theses & Dissertations

Many young adults are experiencing human sexuality related issues and disorders. Researchers have found ample evidence linking hindered human sexuality discussions with clients by mental health professionals to low and reduced comfort, lack of willingness, and non-positive attitudes about sex. There is limited research that shows there is a connection between sex-based discussions in the field of mental health and the lack of clinicians’ education and training in the field of human sexuality. One of the most essential ways to identify, treat, and promote sexual health is a thorough sexual history taking by clinicians. Mental health professionals agree that taking …

Representations And Perceptions Of Sexual Pleasure In Undergraduate Anatomy And Physiology (A&P) Courses, Brenda Kucha Anak Ganeng

Graduate Research Theses & Dissertations

The World Health Organization defines sexual pleasure as an important part of positive sexual experiences and sexual health. Despite its importance, sexual pleasure is often omitted from sexual health programming and curricula. Undergraduate human anatomy and physiology (A&P) courses serve as avenues where students who intend to go into health care learn foundational knowledge about human body systems and health; however, to our knowledge, there has been no documentation of if and how A&P students learn about sexual pleasure. A&P textbooks serve as an important resource for curriculum design and learning. I sought to answer the following research question: How …

Disparities In Cervical Cancer Survival Amongst White And African American Women, Lucius Amandi-Tasie Ogoke

Walden Dissertations and Doctoral Studies

Cervical cancer disproportionately impacts racial and ethnic minorities in the United States. The continuum in the disturbing morbidity and mortality trends declined markedly in 2020. However, there are more than 13,000 diagnosed cases, and almost 4,300 related deaths, and significant racial disparities in cervical cancer survival persist. The socio-ecological model served as the theoretical framework. Chi-square tests and binary logistic regression analyses were used to analyze data from the National Cancer Institute Surveillance, Epidemiology, and Ends Results Summary. The purpose of the study was to assess the association between race/ethnicity-related disparities in sociodemographic, histopathological, and treatment-related factors and cervical cancer …

The Interrelationship Between Treatment, Ethnicity, And Structured Exercise In Clinical Populations, Amanda M. F. Lopez

University of the Pacific Theses and Dissertations

Cancer is the second leading cause of death, with about approximately 1.9 million Americans being diagnosed each year. Yet, it has high survival rates with the help of advancing treatments like radiation therapy. Cancer patients and survivors are contingent on experiencing a decline in physical functioning, quality of life, and physiological parameters. Treatment is effective and can prolong life expectancy but can be deleterious to a patient’s health. Parallel with cancer's impact on Americans is cardiovascular disease. Cardiovascular disease is responsible for 1 in 4 deaths. The development of cardiovascular disease is not spread accordantly among all ethnicities. Hispanics are …

Head-Mounted Digital Metamorphopsia Suppression As A Countermeasure For Macular-Related Visual Distortions For Prolonged Spaceflight Missions And Terrestrial Health, Joshua Ong, Nasif Zaman, Ethan Waisberg, Sharif Amit Kamran, Andrew G Lee, Alireza Tavakkoli

Faculty, Staff and Student Publications

During long-duration spaceflight, astronauts are exposed to various risks including spaceflight-associated neuro-ocular syndrome, which serves as a risk to astronaut vision and a potential physiological barrier to future spaceflight. When considering exploration missions that may expose astronauts to longer periods of microgravity, radiation exposure, and natural aging processes during spaceflight, more severe changes to functional vision may occur. The macula plays a critical role in central vision and disruptions to this key area in the eye may compromise functional vision and mission performance. In this article, we describe the development of a countermeasure technique to digitally suppress monocular central visual …

The Influence Of Perceived Value, User Engagement, And Emotions On Usage Intention Of Thai Tiktok Users, Phakkhaporn Dancharoenpol

Chulalongkorn University Theses and Dissertations (Chula ETD)

The objectives of this research were to explore perceived value, user engagement, emotions, and usage intention of Thai TikTok users, as well as to investigate the influence of perceived value, user engagement, and emotions on TikTok usage intention. An online survey was employed to collect data from 289 participants who were TikTok users, aged between 18-38 years old. The findings showed that the respondents had high perceived value (M = 4.01), high engagement (M = 3.78), emotions (M = 3.75), and high usage intention (M = 3.97) towards TikTok. Furthermore, the results of the multiple regression analysis depicted that perceived …

A Personal History Of The Department Of Biology, Margaret L. May

VCU University History Books

Former faculty member Margaret May recounts the history and development of the Department of Biology at Virginia Commonwealth University.

Study Of Saliva Transcriptome And Proteome In Thai Patients With Dental Fluorosis, Patcharaporn Gavila

Chulalongkorn University Theses and Dissertations (Chula ETD)

The purpose of this study was to examine the expression profiles of RNA and protein in Thai individuals with dental fluorosis and compare them with those without fluorosis. Additionally, the study aimed to establish a correlation between the severity of dental fluorosis, urinary fluoride levels, and water fluoride levels. Methods: Schoolchildren in areas endemic for fluoride in Lamphun and Ratchaburi provinces of Thailand were screened for dental fluorosis severity and then enrolled in the study. Fluoride concentration in 24-hour urine and drinking water samples was measured using an ion-selective fluoride electrode. Saliva samples were collected in sterile tubes and stored …

Understanding Chinese International Students' Engagement And Belongingness In U.S. Universities, Yingying Jiang

Theses and Dissertations

Little research has been conducted on Chinese international students’ engagement and belongingness in U.S. universities. This study used a non-experimental quantitative survey research design and adapted survey items from past literature to target Chinese international students’ experiences. Prior to the survey administration, pretesting including expert reviews and a think-aloud were carried out to validate the survey. A total of 76 Chinese students from various universities participated in the survey data collection. The quantitative analytical processes included Confirmatory Factor Analysis (CFA) to ensure construct validity; measurement invariance testing between groups and Structural Equation Modeling (SEM) included four major factors/predictors (English proficiency, …

Identification Of Circulating Plasma Ceramides As A Potential Sexually Dimorphic Biomarker Of Pancreatic Cancer-Induced Cachexia., Jeffery M Chakedis, Mary E Dillhoff, Carl R Schmidt, Priyani V Rajasekera, David C Evans, Terence M Williams, Denis C Guttridge, Erin E Talbert

Oncology Articles

BACKGROUND: Cancer patients who exhibit cachexia lose weight and have low treatment tolerance and poor outcomes compared to cancer patients without weight loss. Despite the clear increased risk for patients, diagnosing cachexia still often relies on self-reported weight loss. A reliable biomarker to identify patients with cancer cachexia would be a valuable tool to improve clinical decision making and identification of patients at risk of adverse outcomes.

METHODS: Targeted metabolomics, that included panels of amino acids, tricarboxylic acids, fatty acids, acylcarnitines, and sphingolipids, were conducted on plasma samples from patients with confirmed pancreatic ductal adenocarcinoma (PDAC) with and without cachexia …

Oscillations Of The Circadian Clock Protein, Bmal-1, Align To Daily Cycles Of Mechanical Stimuli: A Novel Means To Integrate Biological Time Within Predictive In Vitro Model Systems, Hannah K Heywood, Laurence Gardner, Martin M Knight, David A Lee

Faculty, Staff and Student Publications

PURPOSE: In vivo, the circadian clock drives 24-h rhythms in human physiology. Isolated cells in vitro retain a functional clockwork but lack necessary timing cues resulting in the rapid loss of tissue-level circadian rhythms. This study tests the hypothesis that repeated daily mechanical stimulation acts as a timing cue for the circadian clockwork. The delineation and integration of circadian timing cues into predictive in vitro model systems, including organ-on-a-chip (OOAC) devices, represent a novel concept that introduces a key component of in vivo physiology into predictive in vitro model systems.

METHODS: Quiescent bovine chondrocytes were entrained for 3 days by …

T Cell Changes Induced By Dietary/Weight Change, Aljowhara Aljeraiwi

Electronic Theses and Dissertations Archive

Obesity is a condition that affects many people and is associated with numerous health issues and chronic diseases, including viral infections. For example, during the SARS-CoV2 epidemic, obesity emerged as a major risk for severe COVID 19. Obesity has been shown to increase T cell exhaustion resulting in loss of CD8+ T cell functions and reducing the immune system's capacity to fight infectious diseases. Exhausted T cells can be identified by the increased expression of the membrane protein Programmed Cell Death 1 (PD-1). While many studies demonstrate that a high-fat diet and an increase in weight can affect the immune …

A Neural Network-Based Model For Lower Limb Continuous Estimation Against The Disturbance Of Uncertainty, Wanting Li, Keping Liu, Zhongbo Sun, C Li, Yuanyuan Chai, Jian Gu

School of Engineering, Computing and Mathematics

In this paper, a novel prediction model is proposed to estimate human continuous motion intention using a fuzzy wavelet neural network (FWNN) and a zeroing neural network (ZNN). During walking, seven channel surface electromyography (sEMG) signals and motion data of hip and knee are collected, and two signals are selected and processed from the seven muscles based on physiological and correlation analysis. Then, FWNN is built as an intention recognition model, with sEMG signals as input and physical hip and knee information as output. Meanwhile, ZNN is exploited into the FWNN model, forming a hybrid model to eliminate the prediction …

Crowdsourcing Platform For Qoe Evaluation For Cloud Multimedia Services, A Laghari, Hui He, Asiya Khan, R Laghari, Shoulin Yin, Jiachi Wang

School of Engineering, Computing and Mathematics

This paper presents a novel web-based crowdsourcing platform for the assessment of the subjective and objective quality of experience (QoE) of the video service in the cloud-server environment. The user has the option to enter subjective QoE data for video service by filling out a web questionnaire. The objective QoE data of the cloud-server, network condition, and the user device is automatically captured by the crowdsourcing platform. Our proposed system collects both objective and subjective QoE simultaneously in real-time. The paper presents the key technologies used in the development of the platform and describes the functional requirements and design ideas …

The Impact Of Integrating Oral Health Education Into A Human Physiology Curriculum For Students Of Early Childhood Education, Ming-Chung Lee, Ling-Hsia Wang, Tzu-Chiang Lin, Yung-Ta Chang, Feng-Chou Cheng, Chun-Pin Chiang

Journal of Dental Sciences

Abstract Background/purpose The good oral health plays a pivotal role in improving the general health of the body. The purpose of this study was to evaluate an innovative design incorporating oral health education into a human physiology curriculum for students of early childhood education by evaluating the students’ perspectives on the oral health curriculum. Materials and methods Forty-two first-year students who took the compulsory course entitled “Introduction to Human Physiology” in National Taiwan Normal University in 2022 were invited to fill out the questionnaire for a presurvey regarding their familiarity with basic oral health concepts, and a postsurvey in which …

Systematic Profiling Of Dnmt3a Variants Reveals Protein Instability Mediated By The Dcaf8 E3 Ubiquitin Ligase Adaptor, Yung-Hsin Huang, Chun-Wei Chen, Venkatasubramaniam Sundaramurthy, Mikołaj Słabicki, Dapeng Hao, Caroline J Watson, Ayala Tovy, Jaime M Reyes, Olga Dakhova, Brielle R Crovetti, Christina Galonska, Minjung Lee, Lorenzo Brunetti, Yubin Zhou, Katrina Tatton-Brown, Yun Huang, Xiaodong Cheng, Alexander Meissner, Peter J M Valk, Lionel Van Maldergem, Mathijs A Sanders, Jamie R Blundell, Wei Li, Benjamin L Ebert, Margaret A Goodell

Faculty, Staff and Students Publications

Clonal hematopoiesis is a prevalent age-related condition associated with a greatly increased risk of hematologic disease; mutations in DNA methyltransferase 3A (DNMT3A) are the most common driver of this state. DNMT3A variants occur across the gene with some particularly associated with malignancy, but the functional relevance and mechanisms of pathogenesis of the majority of mutations are unknown. Here, we systematically investigated the methyltransferase activity and protein stability of 253 disease-associated DNMT3A mutations, and found that 74% were loss-of-function mutations. Half of these variants exhibited reduced protein stability and, as a class, correlated with greater clonal expansion and acute …

Steroid Receptor Coactivators – Their Role In Immunity, Yosi Gilad, David M Lonard, Bert W O'Malley

Faculty, Staff and Students Publications

Steroid Receptor Coactivators (SRCs) are essential regulators of transcription with a wide range of impact on human physiology and pathology. In immunology, SRCs play multiple roles; they are involved in the regulation of nuclear factor-κB (NF-κB), macrophage (MΦ) activity, lymphoid cells proliferation, development and function, to name just a few. The three SRC family members, SRC-1, SRC-2 and SRC-3, can exert their immunological function either in an independent manner or act in synergy with each other. In certain biological contexts, one SRC family member can compensate for lack of activity of another member, while in other cases one SRC can …

Child Dietary Patterns In Homo Sapiens Evolution: A Systematic Review, Lora L Iannotti, Emmanuel A Gyimah, Miranda Reid, Melissa Chapnick, Mary Kate Cartmill, Chessa K Lutter, Charles Hilton, Theresa E Gildner, Elizabeth A Quinn

2020-Current year OA Pubs

Dietary patterns spanning millennia could inform contemporary public health nutrition. Children are largely absent from evidence describing diets throughout human evolution, despite prevalent malnutrition today signaling a potential genome-environment divergence. This systematic review aimed to identify dietary patterns of children ages 6 months to 10 years consumed before the widespread adoption of agriculture. Metrics of mention frequency (counts of food types reported) and food groups (globally standardized categories) were applied to: compare diets across subsistence modes [gatherer-hunter-fisher (GHF), early agriculture (EA) groups]; examine diet quality and diversity; and characterize differences by life course phase and environmental context defined using Köppen-Geiger …