Digital Commons Network^™

A Narrative Inquiry Into Veterans In Engineering, Miracle David Solley

Graduate Theses, Dissertations, and Problem Reports (ETD)

Much research has been conducted on student veterans, in general; however, research on student veterans in engineering majors is very sparse. There is national recognition of the importance of student veterans in science, technology, engineering, and mathematics (STEM) fields as evidenced in the passage in 2020 of a bill investigating the lack of veteran students in these fields. This study adds to the literature by answering the following two research questions: What are the experiences of veteran engineering students? How has military service impacted those experiences? Twelve students and five professors from a Doctoral University: Very High Research Activity in …

Advancing Compound Detection And Identification Using Vibrating Sharp-Edge Spray Ionization, Anthony Paul Debastiani

Graduate Theses, Dissertations, and Problem Reports (ETD)

Advancing Compound Detection and Identification Using Vibrating Sharp-Edge Spray Ionization

Anthony Paul DeBastiani

‘Omics consists of various areas, including genomics, proteomics, lipidomics, and metabolomics with a goal of detection and identification of biomolecules present within each of these classes within an organism. Current omic analytical methods include the use of mass spectrometry (MS) coupled with various separation techniques, including liquid chromatography (LC), with the use of heated nebulization gas assisted electrospray ionization (HESI). Although the rapid progress in LC-MS platform development has lead to significant enhancements in omic studies, significant limitations in the detection and identification of low abundant species …

Integrated Large Discontinuity Factor, Lamodel And Stability Mapping Approach For Stone Mine Pillar Stability, Mustafa Baris Ates

Graduate Theses, Dissertations, and Problem Reports (ETD)

The objective of this research is to develop a software tool that integrates the large discontinuity factor (LDF) and the Boundary Element Method software (BEM), LaModel, to allow stone mine operators to assess the impact of the large discontinuities on local pillar stability. National Institute for Occupational Safety and Health (NIOSH) published design guidelines for underground stone mines to guide the industry in designing pillar and roof support. These guidelines emphasize the impact of large, angular discontinuities on pillar strength. Esterhuizen et al. (2011) derived the large discontinuity factor (LDF) to account for the impact of discontinuities on pillar stability …

The Process And Case Study Approach To Implementing A Nutrition-Specific Dissemination And Implementation Science Training In Appalachia, Ayron E. Walker

Graduate Theses, Dissertations, and Problem Reports (ETD)

Introduction: Nutrition professionals face implementation challenges due to their lack of knowledge to incorporate D&I science into intervention design. To improve intervention outcomes, nutrition professionals must be trained in D&I science, which are currently absent in the field.

Aims: To identify and assess nutrition educators and practitioners perceived motivations, self-efficacy, and attitudes in using D&I science to inform the educational design and strategies of a nutrition-specific D&I curriculum for nutrition educators. Then to test feasibility of the nutrition-specific curriculum in increasing knowledge, self-efficacy, and attitudes by a case study approach, pre/post intervention design.

Methods: First, scoping review methodology involved the …

Gun Culture 3.0, Andrew Phillip Stover

Graduate Theses, Dissertations, and Problem Reports (ETD)

There exist a criminology of firearms and an epidemiology of firearms use, but little in the way of a sociology of U.S. firearm ownership. Most social science study of firearms concerns illicit gun use and the harm that use produces. Compared to this body of work, little has been done to explore the culture of legal gun ownership. A few social scientists have attempted to change this by contributing their own interpretations of what a sociology of U.S. gun ownership might look like. Professor David Yamane, in doing just this, has posited a cultural model of contemporary gun ownership he …

“I Lost Everything I Owned… Now I’M Growing That Back”: Narratives Of Redemption After Meth Immersed Lives, Danielle M. Stoneberg

Graduate Theses, Dissertations, and Problem Reports (ETD)

There is a lack of knowledge on how the process of desisting (i.e., maintaining abstinence) works for those leaving immersed drug lifestyles, leaving a need for a better understanding of the role and impact of identity in drug desistance. Through secondary analysis of interview data from a sample of 33 former methamphetamine manufacturers, this study examines the applicability of Maruna’s (2001) redemption narrative framework and identifies other aspects featured in their narratives that signaled identity change. Results found all participants discussed at least one component of the framework in their interviews. Their narrative identities changed over time to recognize that …

Utilizing The K18-Hace2 Mouse Model To Develop Protective Covid-19 Vaccines, Ting Y. Wong

Graduate Theses, Dissertations, and Problem Reports (ETD)

The ongoing Coronavirus Disease 2019 (COVID-19) pandemic is caused by the respiratory virus Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Similar to other respiratory viruses, SARS-CoV-2 is transmitted through inhalation of respiratory droplets and aerosols from infected individuals. Once inhaled, SARS-CoV-2 utilizes the receptor binding domain (RBD) on the spike protein to bind to human Angiotensin Converting Enzyme 2 (hACE2) receptor to gain entrance into host cells to begin viral replication. SARS-CoV-2 infection can result in mild to severe cases of COVID-19 ranging from asymptomatic infections, cold or flu like symptoms to respiratory failure. The onset of the pandemic in …

Essays In Urban And Health Economics, Allyssa Ann Wadsworth

Graduate Theses, Dissertations, and Problem Reports (ETD)

Chapter 1 analyzes the impact new hospital construction has on neighboring residential real estate prices. In 2017, the Oishei Children’s Hospital was built in downtown Buffalo, New York, representing a new era for women and children’s medical facilities. Individuals working at the old facility now faced the decision of whether to move closer to the new hospital or have a longer commute. Using property sales data, I analyze how Oishei impacts residential property prices with a difference-in-differences hedonic price model while utilizing three unique time treatments and two distance treatments. The opening of Oishei generated a statistically significant percentage increase …

An Examination Of Hip Muscle Activation In Those With Hip-Related Groin Pain During Single-Legged And Double-Legged Squats, Millissia A. Murro

Graduate Theses, Dissertations, and Problem Reports (ETD)

Approximately 60% of young adults who present with chronic hip pain suffer from hip-related groin pain (HRGP). HRGP causes individuals to experience pain, dysfunction, and have a lower quality of life when compared to healthy individuals. The most severe symptoms in these individuals occur during activities that cause the hip to go through a large range of motion, such as a squat. Hip muscle activation during this task may be altered in these individuals, yet we know little about its role in the disease process and pain level in those with HRGP. Current treatment for these individuals includes surgical and …

Examining The Pulmonary Response To Repeated Vishniacozyma Victoriae Exposure And Its Association With Allergic Airway Disease, Rachael Erin Rush

Graduate Theses, Dissertations, and Problem Reports (ETD)

Allergic airway diseases such as asthma continue to increase in incidence in industrialized nations like the United States. These diseases are complex inflammatory processes involving numerous cells and mediators and are strongly influenced by fungal exposures. Recent developments in fungal detection methods have highlighted the contribution of Basidiomycota yeast species in indoor environments such as Vishniacozyma (syn. Cryptococcus) victoriae. However, despite the high levels of this yeast detected in indoor environments, very little is known about it or its role in respiratory morbidity. V. victoriae is phylogenetically similar to pathogenic Cryptococcus neoformans but lacks a capsule and is …

Freeze! The Impact Of A Guided Imagery Intervention On Looming Vulnerability And Subclinical Contamination-Ocd Symptoms, Amber Lynn Billingsley

Graduate Theses, Dissertations, and Problem Reports (ETD)

Looming vulnerability (LV) refers to the tendency to appraise and perceive potential threats as dynamic and increasing in risk. Research suggests that contamination-fearful individuals may have an increased tendency to interpret contamination as growing or spreading (i.e., “looming”), which may hinder habituation to contamination and play a role in the maintenance of contamination-OCD symptoms. Studies have shown that engaging in imagery in which one mentally freezes contamination in place decreases state levels of fear, though little is known about its longer-term effects (e.g., after one week). The present study aimed to experimentally manipulate LV using freeze imagery in a subclinical …

Embodied Energy Geographies: An Exploration Of Fracked Landscapes In The Ohio River Valley, Rachael L. Hood

Graduate Theses, Dissertations, and Problem Reports (ETD)

Methane gas production has boomed across the United States as a result of the development of fracking technology and its associated infrastructures, including pipelines. This production has provoked resistance over a litany of environmental and social concerns at both global and local scales. These concerns are compounded by a history of extractive economies and degradation in the Marcellus shale region of Appalachia and the Ohio River Valley. To date, there has been limited research at the intersection of extractive industry and emotional geography, especially around pipelines. This research draws on feminist, emotional, and energy geographies and uses semi-structured interviews and …

Targeting Vulnerabilities In Cell State And Calcium Signaling For The Treatment Of Lung Cancer, Clark Jones

Graduate Theses, Dissertations, and Problem Reports (ETD)

Lung cancer remains the deadliest of all cancers due to the high mutational burden associated with the disease. Combating mutational drivers and drug resistance proves to be essential in the development of novel therapies to improve patient outcomes. A first-in-class cyclic peptide known as MTI-101 has been shown to induce necrotic cell death in a caspase independent manner. MTI-101 was derived from the linear peptide known as HYD1 that was found in a high throughput screen to block cell adhesion with the extracellular matrix. The compound was further optimized and cyclized to the currently used MTI-101 that was found to …

The Impact Of Perceived Daily Racism And Racial Identity Development On Body Dissatisfaction Among Asian American Female College Students, Mary E. Burkhart Polk

Graduate Theses, Dissertations, and Problem Reports (ETD)

Eating disorders pose a significant health problem for a diverse group of people. However, knowledge regarding their origins and appropriate treatments has not expanded, more specifically for Asian Americans. This study aimed to increase the knowledge surrounding an essential component of disordered eating, body dissatisfaction, and potential factors in its development. Specifically, the impact of experiences of daily racism and racial identity development on body dissatisfaction among Asian American college women were examined. Using a non-experimental, quantitative survey design, this study assessed the relationship between perceived daily racism and the racial identity schema Internalization on the endorsement of body dissatisfaction …

Athlete Attachment Style With Coaches As A Predictor Of Athlete Disordered Eating And Body Image Anxiety, Taylor Allen

Graduate Theses, Dissertations, and Problem Reports (ETD)

The coach-athlete relationship has been established as an important and significant relationship within athletes’ lives (Davis & Jowett, 2010; Jowett, 2008). There is also literature that demonstrates the impact of the sport culture environment and the quality of the coach-athlete relationship on disordered eating and body image anxiety in athletes (Galli et al., 2011; Petrie & Greenleaf, 2012; Reel et al., 2010; Shanmugam et al., 2013). However, much of the current literature does not examine this significant coach-athlete relationship from an attachment framework. Current literature supports the significance of the coach-athlete relationship and more recent research supports viewing coaches as …

Methodology For Enhanced Filtration And Dewatering Of Fine-Grain Amd Precipitate Using Geocomposites For Rare Earth Elements Recovery, Iuri Lira Santos

Graduate Theses, Dissertations, and Problem Reports (ETD)

Research performed by the West Virginia Water Research Institute (WVWRI) in partnership with the Department of Energy (DOE) has identified that coal mining by-products contain significant amounts of Rare Earth Elements (REEs). REEs currently are in high demand, and extraction from coal mining reject presents a potential for commercialization if extraction is feasible. The coal mining reject include Acid Mine Drainage (AMD) in the aqueous phase and sludge from AMD treatment. A novel two split selective precipitation method was implemented to remove gangue metals, increasing the concentration of REEs in the sludge.

This process presents a two-fold benefit: 1) treatment …

Reinforcement Learning For Process Control: Applications To Energy Systems, Elijah Ballard Hedrick

Graduate Theses, Dissertations, and Problem Reports (ETD)

Reinforcement learning (RL) is a machine learning method that has recently seen significant research activity owing to its successes in the areas of robotics and gameplaying (Silver et al., 2017). However, significant challenges exist in the extension of these control methods to process control problems, where state and input signals are nearly always continuous and more stringent performance guarantees are required. The goal of this work is to explore ways that modern RL algorithms can be adapted to handle process control problems; avenues for this work include using RL with existing controllers such as model predictive control (MPC) and adapting …

Investigation Of Geomechanical Behavior Of Laminated Rock Mass Through Experimental And Numerical Approach, Qingwen Shi

Graduate Theses, Dissertations, and Problem Reports (ETD)

Roof failure in the Appalachian underground coal fields occurs often in laminated shale. Laminated shale roof in coal mines fails in unique ways, such as cutter failure or delamination failure. Extensive studies have investigated the influential factors that cause laminated roof failure, which include in-situ stress, entry layout, roof span, and roof support. However, cutter failure continues to occur frequently and erratically. This is due to the lack of in-depth understanding of the inherent properties of the laminations, such as bedding plane strength, matrix strength, and bedding plane spacing, which in turn influence the geomechanical behavior of the laminated rock. …

Investigating The Mitochondrial Protein Mitoneet In C. Elegans Models Of Aging And Alzheimer's Disease, Jacob Ryan Boos

Graduate Theses, Dissertations, and Problem Reports (ETD)

Oxidative stress is an imbalance between reactive oxygen species production and elimination, favoring the former. Reactive oxygen species serve as important signaling molecules for physiological homeostasis. However, when produced in excess, these once important signaling molecules become detrimental, disrupting cellular functions, and ultimately leading to cell death. In aging, reactive oxygen species production is increased, accompanied with reductions in oxidative stress resistance, increasing the risk for developing age-related diseases including cardiovascular disease, cancer, stroke, and neurodegenerative diseases. The outer mitochondrial membrane iron-sulfur cluster containing protein mitoNEET (CISD1; gene CISD1) has shown to be a mediator of mitochondrial function and …

Performance Of Peltier Cooled Technology During Preconcentration Of Volatile Organic Compounds Analyzed By Gas Chromatography-Mass Spectrometry (Gc-Ms) Using Niosh Manual Of Analytical Methods (Nmam) 3900, Elizabeth Ann Fernandez

Graduate Theses, Dissertations, and Problem Reports (ETD)

Using evacuated canisters for whole-air sampling allows for sampling without specific knowledge of the environment and potential analytes. Evacuated canisters are able to tolerate concentrations ranging from parts per trillion (PPT) to parts per million (PPM). The U.S. Environmental Protection Agency (EPA) has used evacuated canisters for years to sample volatile organic compounds (VOCs) from ambient air using their method TO-15 (LeBouf, et al., 2019). The GC-MS system used for the development of NMAM 3900 used liquid nitrogen to cool sorbent traps in the preconcentrator. Liquid nitrogen allows for cooling of specified points below ambient temperature. An alternative to liquid …

Mountain Biking Mountaineers: Insights Into The West Virginia Mountain Biking Community, Connor Mullin

Graduate Theses, Dissertations, and Problem Reports (ETD)

Mountain biking is one of the most popular recreational activities in the United States. Beyond the increasing popularity of the sport, the technology is also changing, especially in terms of electric mountain biking. This new type of bike blends traditional mountain bikes with electric bikes, creating a potential new group of recreationists. The research on mountain biking, and more specifically electric mountain biking, is limited. The purpose of this study is to examine West Virginian mountain bikers by studying behaviors and motivations. There are no published studies focused on mountain biking in West Virginia, and therefore a need to fill …

High Precision Pipeline Leak Detection And Localization Using Negative Pressure Wave Technique: An Application In A Real Field Case Study, Nathaniel C. Moryan

Graduate Theses, Dissertations, and Problem Reports (ETD)

One of the most important aspects of oil and gas production is the safe and efficient fluid transportation using pipelines. Pipelines transporting various fluids are the most efficient but are susceptible to failure and leaks. These leaks can come about through natural disaster, as well as from general wear from the pipes that could result in major environmental and economic problems. The ability to detect leaks with speed and accuracy, as well as locating these leaks within a narrow range, will aid with the maintenance response. Hasty responses will minimize the revenue loss and reduce potential environmental impact but bring …

Developing Artificial Intelligence Tools To Investigate The Phenotypes And Correlates Of Chronic Kidney Disease Patients In West Virginia, Marzieh Amiri Shahbazi

Graduate Theses, Dissertations, and Problem Reports (ETD)

ABSTRACT

Developing Artificial Intelligence tools to investigate the phenotypes and correlates of Chronic Kidney Disease patients in West Virginia

Marzieh Amiri Shahbazi

Chronic kidney disease (CKD) is responsible for disrupting the lives of 37 million people just in the USA, which is about 1 in 7 adults. CKD results in a gradual loss of kidney function over time. Sometimes CKD doesn’t produce any significant symptoms until it reaches an advanced stage. On the other hand, acute kidney injury (AKI) accounts for a sudden decline in the kidney’s function. As a result, the kidneys fail to filter waste materials from the …

Exploiting Modulation Of The Blood-Brain And Blood-Tumor Barrier Permeability By Translational Focused Ultrasound For Therapeutic Delivery To Cns Metastases, Tasneem A. Arsiwala

Graduate Theses, Dissertations, and Problem Reports (ETD)

Transcranial low-intensity focused ultrasound is a unique technology to modulate the integrity of tight endothelial junctions and transiently increase BBB/BTB permeability to enhance therapeutic delivery. Despite promising early studies, present literature lacks agreement on key experimental conditions, which restricts our knowledge and the technique's widespread translation. This dissertation first provides a critical review of the current gaps in knowledge regarding the universal use of LiFUS in preclinical and clinical use. We then identify key parameters for translational and predictable opening of the BBB using a 3T MRI coupled with a clinical device. Our investigation highlights that passive permeability of the …

System Development Of An Unmanned Ground Vehicle And Implementation Of An Autonomous Navigation Module In A Mine Environment, Jonas Amoama Bredu Jnr

Graduate Theses, Dissertations, and Problem Reports (ETD)

There are numerous benefits to the insights gained from the exploration and exploitation of underground mines. There are also great risks and challenges involved, such as accidents that have claimed many lives. To avoid these accidents, inspections of the large mines were carried out by the miners, which is not always economically feasible and puts the safety of the inspectors at risk. Despite the progress in the development of robotic systems, autonomous navigation, localization and mapping algorithms, these environments remain particularly demanding for these systems. The successful implementation of the autonomous unmanned system will allow mine workers to autonomously determine …

Understanding Vaccine-Induced Memory Responses To Develop The Next Generation Of Pertussis Vaccines, Kelly L. Weaver

Graduate Theses, Dissertations, and Problem Reports (ETD)

Bordetella pertussis is a Gram-negative respiratory pathogen that can infect individuals of all ages and is notably responsible for infant fatalities. Pertussis (whooping cough) is a vaccine-preventable respiratory disease for which vaccines have been available in the United States since the 1940s. Whole cell pertussis vaccines kept incidence of pertussis under 5,000 cases per year, but were associated with reactogenicity issues. Following the introduction of less reactogenic acellular pertussis vaccines in the late 1990s, there have been noteworthy outbreaks of pertussis. For example, in 2012 there were over 50,000 reported cases of pertussis and 20 deaths in the U.S. The …

Noise Exposure Trends Among Violating Coal Mines, 2000 To 2021, Hanna Grace Davis

Graduate Theses, Dissertations, and Problem Reports (ETD)

Noise-induced hearing loss has continued to be a significant issue within the mining industry, even after the passing of the MSHA’s improved noise standard in 2000. NIOSH has recognized that the noise standard enacted by both MSHA and OSHA does not properly protect workers with the 5 dBA exchange rate (i.e., the increase in noise level leading to a doubling of energy) and the lack of emphasizing the use of engineering controls over administrative controls and overreliance on hearing protection device usage. The primary objective of this study is to investigate statistical sound relationships between MSHA noise-related violations and samples …

Living On The Edge: Trans* Exclusion, Survival, And Resistance, Rayna E. Momen

Graduate Theses, Dissertations, and Problem Reports (ETD)

ABSTRACT

This dissertation focuses on the criminalization and victimization of transgender people, broadly defined as people whose gender identity does not align with their assigned birth sex, using a queer criminological and intersectional lens. The introduction offers background and context for this examination, and includes the purpose, theoretical approach, methodology, research questions, contributions, and overviews of the substantive chapters. Chapter two explores what we know and what we do not know about transgender people’s pathways into the criminal legal system, how they experience state surveillance, and how they navigate the system. Chapter three explores violence against transgender people in various …

Calcite Depression In Bastnaesite-Calcite Flotation System Using Organic Acids, Emmy Muhoza

Graduate Theses, Dissertations, and Problem Reports (ETD)

Bastnaesite is the primary source of light REEs, namely cerium (Ce), lanthanum (La), praseodymium (Pr), neodymium (Nd), to name a few. Bastnaesite is typically concentrated using the froth flotation beneficiation method. Flotation of bastnaesite suffers from high reagent consumption due to the similar surface characteristics of bastnaesite and associated gangue minerals, including calcite. Additionally, complex stages of high-temperature conditioning are often required to suppress the detrimental impact of dissolved calcium ions on the flotation of bastnaesite. This research seeks to investigate the capabilities of organic acids in the bastnaesite-calcite flotation systems to selectively depress calcite minerals and effectively chelate calcium …

Exploration Of Intercollegiate Student-Athletes’ Athletic Identity, Leah C. Oldham

Graduate Theses, Dissertations, and Problem Reports (ETD)

Student-athletes encounter experiences that can cause their identity process and self-concept to be disturbed. Even though athletic identities are strong among intercollegiate athletes, some encounter identity-threatening events that interrupt their identity process, negatively affecting their athletic identity. The present study adds to current research on the athletic identity of student-athletes by examining the athletic identity and self-esteem of student-athletes to determine if a redshirt season is a positive (identity-enhancing) or negative (identity-threatening) event. The intersectionality of age, race, gender, and ethnicity are examined to understand if multiple identities influence the experience of a redshirt season. Results reveal that a redshirt …