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2022

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Implementation Of A Nonverbal Scrub Cap Identification System To Improve Communication And Perception Of Patient Safety Among Unfamiliar, De-Identified Staff Members In The Operating Room., Keri Ann Roskowinski Jan 2022

Implementation Of A Nonverbal Scrub Cap Identification System To Improve Communication And Perception Of Patient Safety Among Unfamiliar, De-Identified Staff Members In The Operating Room., Keri Ann Roskowinski

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background: Operating room (OR), professionals deliver patient care with brief introductions, and roles were not always identified, and although team members wear identification (ID) badges, they were usually covered by sterile gowns and other routine personal protective equipment (PPE). Purpose: The aim of this Doctor of Nursing Practice (DNP) project was to determine if a simple intervention to apply the individual’s name and role to a scrub cap could improve identification, OR team communication, and consequently, patient safety. The participants in this project consisted of nurses, physicians, anesthesia providers, scrub technicians, students, medical sales representatives, and those that identified as …


With All Your Heart For A Lifetime, Jasmine Fraser Jan 2022

With All Your Heart For A Lifetime, Jasmine Fraser

Faculty Publications

No abstract provided.


Optimal Illiquidity, John Beshears, James J. Choi, Christopher Clayton, Christopher Harris, David Laibson, Brigitte C. Madrian Jan 2022

Optimal Illiquidity, John Beshears, James J. Choi, Christopher Clayton, Christopher Harris, David Laibson, Brigitte C. Madrian

Faculty Publications

We calculate the socially optimal level of illiquidity in an economy populated by households with taste shocks and present bias (Amador, Werning, and Angeletos 2006). The government chooses mandatory contributions to respective spending/ savings accounts, each with a different pre-retirement withdrawal penalty. Penalties collected by the government are redistributed through the tax system. When naive households have heterogeneous present bias, the social optimum is well approximated by a three-account system: (i) a completely liquid account, (ii) a completely illiquid account, and (iii) an account with an ≃ 10% early withdrawal penalty. In some ways this resembles the U.S. system, which …


Incremental Improvements: Examining Instructional Changes And Rationales Of K-12 Online Teachers Using The Picrat And 4e Frameworks, Jered Borup, Rocio Quiroga Velasquez, Charles R. Graham, Leanna Archambault, Royce Kimmons Jan 2022

Incremental Improvements: Examining Instructional Changes And Rationales Of K-12 Online Teachers Using The Picrat And 4e Frameworks, Jered Borup, Rocio Quiroga Velasquez, Charles R. Graham, Leanna Archambault, Royce Kimmons

Faculty Publications

Teacher preparation programs have been slow to prepare teachers for the online environment, leaving many online teachers needing to learn on the job. However, little research has examined how online teachers grow as educators. One way to better understand this growth is to examine the changes online teachers make in their instruction and their rationales for making them. In this qualitative case study, we surveyed online teachers three times during an academic year regarding their instructional changes. Participants described these changes and categorized them on a modified PICRAT matrix to indicate if the changes made student learning more passive, interactive, …


Why Arkansas Act 710 Was Upheld, And Will Be Again, Mark Goldfeder Jan 2022

Why Arkansas Act 710 Was Upheld, And Will Be Again, Mark Goldfeder

Scholarly Works

The recent Eighth Circuit ruling in Arkansas Times, LP v. Waldrip, a lawsuit revolving around an Arkansas state anti-discrimination bill, has been widely misreported and generally misunderstood. While the decision was actually very narrow, case-specific, and ripe for review, the misleading information presented to the public has led to speculation and fear that similar anti-discrimination legislation in dozens of other states might somehow be constitutionally deficient. This essay will clarify what actually happened in the Arkansas case, and explain why legislators and advocates around the country do not have to worry about this very limited opinion affecting the legality of …


Preparer Opposition And Strategic Implementation Of Governmental Accounting Standards: Evidence From Public Pension Accounting Reform, Abigail Allen, Reining C. Petacchi Jan 2022

Preparer Opposition And Strategic Implementation Of Governmental Accounting Standards: Evidence From Public Pension Accounting Reform, Abigail Allen, Reining C. Petacchi

Faculty Publications

Widely acknowledged as one of the most controversial standards in governmental accounting, GASB 67/68 radically altered both the recognition and measurement for defined benefit public pensions. The standards require the recognition of previously only disclosed unfunded pension liabilities and increase the magnitude of reported pension liabilities by requiring the partial incorporation of a market-based discount rate. While the recognition proposal was unaltered from its initial conception to the final standards, the discount rate proposal was significantly attenuated after the initial proposal met with unanimous preparer opposition. Accordingly, we examine what incentives drive preparer lobbying positions, whether such lobbying is aligned …


The Effect Of Wearable Activity Monitor Presence On Step Counts, William B. Tayler, James D. Lecheminant, Jospeh Price, Christian P. Tadje Jan 2022

The Effect Of Wearable Activity Monitor Presence On Step Counts, William B. Tayler, James D. Lecheminant, Jospeh Price, Christian P. Tadje

Faculty Publications

Objective: In this study, we tested the effect of wearable activity monitors and tracking on physical activity over 2 weeks.

Methods: Ninety young adults participated. Prior to initiation of the study, each participant was asked to download an iPhone app that tracked physical activity level (step counts) but were not told the app’s purpose. Each participant was then randomly assigned to one of 3 groups (N=30/group): (1) measurement awareness, (2) measurement awareness+track/record, or (3) control. Participants in the measurement awareness and the measurement awareness+track/record groups were given a pedometer to wear for 2 weeks. Additionally, participants in the measurement awareness+track/ …


Brokerage Relationships And Analyst Forecasts: Evidence From The Protocol For Broker Recruiting, Braiden Coleman, Michael S. Drake, Joseph Pacelli, Brady Twedt Jan 2022

Brokerage Relationships And Analyst Forecasts: Evidence From The Protocol For Broker Recruiting, Braiden Coleman, Michael S. Drake, Joseph Pacelli, Brady Twedt

Faculty Publications

We offer novel evidence on how the nature of brokerage-client relationships can influence the quality of equity research. We exploit a unique setting provided by the Protocol for Broker Recruiting to examine whether relaxed broker noncompete agreement enforcement generates spillover effects on sell-side analysts. Entry into this agreement reassigns ownership of the client relationship from the brokerage to individual brokers, potentially generating a greater standard of care. Using a generalized difference-in-differences research design, we provide evidence consistent with brokers reducing pressure on analysts to produce optimistic research following protocol entry. This effect is concentrated among less experienced and non-All Star …


A Tale Of Two Index Funds: Full Replication Vs. Representative Sampling*, Travis Dyer, Nicholas Guest Jan 2022

A Tale Of Two Index Funds: Full Replication Vs. Representative Sampling*, Travis Dyer, Nicholas Guest

Faculty Publications

We examine the two approaches used by equity index funds to track their benchmark index. The first, full replication, mimics the index with exactness. The second, representative sampling, holds a subset of the index. We find that samplers trade 3-4 times more, have 30-50% higher expenses and fees, and earn 50-70 basis points lower annual returns, which is substantial given index funds’ mandate to limit tracking error to a few basis points. Besides higher expenses and transaction costs, poor stock picking also seems to contribute to samplers’ return underperformance. Overall, our analyses suggest representative sampling is associated with underperformance.


Representation Of Race And Ethnicity In Counseling And Counseling Psychology Journals, Jared M. Hawkins, Roy A. Bean, Timothy B. Smith, Jonathan G. Sandberg Jan 2022

Representation Of Race And Ethnicity In Counseling And Counseling Psychology Journals, Jared M. Hawkins, Roy A. Bean, Timothy B. Smith, Jonathan G. Sandberg

Faculty Publications

Whereas previous literature reviews have concluded that people of color are underrepresented in psychological literature, the fields of counseling and counseling psychology have taken a clear affirmative stance with respect to human diversity. This study sought to evaluate the representation of people of color in four key journals across the 2000-2019 timespan: The Counseling Psychologist, Journal of Counseling Psychology, Journal of Counseling & Development, and Counselling Psychology Quarterly. Journal articles were coded for several variables, including focus on racial/ethnic minority (REM) groups and article content topics. Results indicated that 757 (26.3%) of the articles were coded REM-focused. Of …


Opioid Medication Use And Blood Dna Methylation: Epigenome-Wide Association Meta-Analysis, Mikyeong Lee, Roby Joehanes, Daniel L. Mccartney, Minjung Kho, Anke Hüls, Annah B. Wyss, Chunyu Liu, Rosie M. Walker, Sharon L.R. Kardia, Thomas S. Wingo, Adam Burkholder, Jiantao Ma, Archie Campbell, Aliza P. Wingo, Tianxiao Huan, Sinjini Sikdar, Amena Keshawarz, David A. Bennett, Jennifer A. Smith, Kathryn L. Evans, Daniel Levy, Stephanie J. London Jan 2022

Opioid Medication Use And Blood Dna Methylation: Epigenome-Wide Association Meta-Analysis, Mikyeong Lee, Roby Joehanes, Daniel L. Mccartney, Minjung Kho, Anke Hüls, Annah B. Wyss, Chunyu Liu, Rosie M. Walker, Sharon L.R. Kardia, Thomas S. Wingo, Adam Burkholder, Jiantao Ma, Archie Campbell, Aliza P. Wingo, Tianxiao Huan, Sinjini Sikdar, Amena Keshawarz, David A. Bennett, Jennifer A. Smith, Kathryn L. Evans, Daniel Levy, Stephanie J. London

Mathematics & Statistics Faculty Publications

Aim: To identify differential methylation related to prescribed opioid use. Methods: This study examined whether blood DNA methylation, measured using Illumina arrays, differs by recent opioid medication use in four population-based cohorts. We meta-analyzed results (282 users; 10,560 nonusers) using inverse-variance weighting. Results: Differential methylation (false discovery rate <0.05) was observed at six CpGs annotated to the following genes: KIAA0226, CPLX2, TDRP, RNF38, TTC23 and GPR179. Integrative epigenomic analyses linked implicated loci to regulatory elements in blood and/or brain. Additionally, 74 CpGs were differentially methylated in males or females. Methylation at significant CpGs correlated with gene expression in blood and/or brain. Conclusion: This study identified DNA …


Do People With Apraxia Of Speech And Aphasia Improve Or Worsen Across Repeated Sequential Word Trials?, Tyson G. Harmon, Adam Jacks, Katarina L. Haley, Jessica D. Richardson, Elizabeth H. Lacey, Peter Turkeltaub Jan 2022

Do People With Apraxia Of Speech And Aphasia Improve Or Worsen Across Repeated Sequential Word Trials?, Tyson G. Harmon, Adam Jacks, Katarina L. Haley, Jessica D. Richardson, Elizabeth H. Lacey, Peter Turkeltaub

Faculty Publications

Purpose:

During motor speech examinations for suspected apraxia of speech (AOS), clients are routinely asked to repeat words several times sequentially. The purpose of this study was to understand the task in terms of the relationship among consecutive attempts. We asked to what extent phonemic accuracy changes across trials and whether the change is predicted by AOS diagnosis and sound production severity.

Method:

One hundred thirty-three participants were assigned to four diagnostic groups based on quantitative metrics (aphasia plus AOS, aphasia-only, and aphasia with two borderline speech profiles). Each participant produced four multisyllabic words 5 times consecutively. These productions were …


Standardizing Assessment Of Spoken Discourse In Aphasia: A Working Group With Deliverables, Tyson G. Harmon, Brielle C. Stark, Manaswita Dutta, Laura L. Murray, Lucy Bryant, Davida Fromm, Brian Macwhinney, Amy E. Ramage, Angela Roberts, Dirk B Den Ouden, Kris Brock, Katy Mckinney-Bock, Eun Jin Paek, Si On Yoon, Charalambos Themistocleous, Hyunsoo Yoo, Katharine Aveni, Stephanie Gutierrez, Saryu Sharma Jan 2022

Standardizing Assessment Of Spoken Discourse In Aphasia: A Working Group With Deliverables, Tyson G. Harmon, Brielle C. Stark, Manaswita Dutta, Laura L. Murray, Lucy Bryant, Davida Fromm, Brian Macwhinney, Amy E. Ramage, Angela Roberts, Dirk B Den Ouden, Kris Brock, Katy Mckinney-Bock, Eun Jin Paek, Si On Yoon, Charalambos Themistocleous, Hyunsoo Yoo, Katharine Aveni, Stephanie Gutierrez, Saryu Sharma

Faculty Publications

Purpose: The heterogeneous nature of measures, methods, and analyses reported in the aphasia spoken discourse literature precludes comparison of outcomes across studies (e.g., meta-analyses) and inhibits replication. Furthermore, funding and time constraints significantly hinder collecting test-retest data on spoken discourse outcomes. This research note describes the development and structure of a working group, designed to address major gaps in the spoken discourse aphasia literature, including a lack of standardization in methodology, analysis, and reporting, as well as nominal data regarding the psychometric properties of spoken discourse outcomes. Method: The initial initiatives for this working group are to (a) propose recommendations …


Mountain Men Reveal Yellowstone: Observations Of Daniel Potts, Warren Ferris, And Osborne Russell In The 1820s And 1830s, Jay H. Buckley, Nathan Benavidez Jan 2022

Mountain Men Reveal Yellowstone: Observations Of Daniel Potts, Warren Ferris, And Osborne Russell In The 1820s And 1830s, Jay H. Buckley, Nathan Benavidez

Faculty Publications

As Yellowstone National Park celebrates its 150th anniversary as the first such park in the world, it is fascinating to rediscover the records of mountain men and and that the same features that enthrall modern visitors captivated them as well. “Sonder” is the realization that other people with whom we share the mortal coil have lived lives just as complex and wonderous as our own. Americans can no better appreciate this than when they stand in Yellowstone National Park today and marvel at the same grandeur mountain men witnessed two hundred years ago.


Mazes In Spanish-English Dual Language Learners After Language Enrichment: A Case Study, Casey L. Taliancich-Klinger, Connie Summers, Kai J. Greene Jan 2022

Mazes In Spanish-English Dual Language Learners After Language Enrichment: A Case Study, Casey L. Taliancich-Klinger, Connie Summers, Kai J. Greene

Faculty Publications

ABSTRACTThe number of Spanish-English dual language learners (DLLs) in the United States continues toincrease every year. In the absence of developmental language norms for DLLs it is importantto learn more about typical language production characteristics to distinguish typical fromatypical language characteristics. An area of language production with conflicting results inthe literature is the production of mazes. Mazes are interruptions in the forward flow oflanguage in the form of interjections, repairs or revisions of words and phrases. At elevatedrates, mazes may interrupt the communication process. A common practice in classroomsettings is to provide support for DLLs through small group activities such …


Suffolk University Academic Catalog, College Of Arts And Sciences And Sawyer Business School, 2022-2023, Suffolk University Jan 2022

Suffolk University Academic Catalog, College Of Arts And Sciences And Sawyer Business School, 2022-2023, Suffolk University

College of Arts and Sciences and Sawyer Business School Academic Catalogs

This catalog contains information for both the undergraduate and graduate programs in the College of Arts and Sciences and the Sawyer Business School.


Developing Standards For Gender-Responsive Human Rights Due Diligence, Constance Z. Wagner, Nancy Kaymar Stafford Jan 2022

Developing Standards For Gender-Responsive Human Rights Due Diligence, Constance Z. Wagner, Nancy Kaymar Stafford

All Faculty Scholarship

This article addresses the current state of gender-responsive human rights due diligence (GR-HRDD) standards and advocates for greater attention to be paid to women’s human rights in the due diligence process. The 2011 United Nations Guiding Principles on Business and Human Rights (UNGPs) created a global framework for recognizing, preventing, and addressing the risk of adverse impacts of human rights violations linked to business activities. The responsibility of businesses to respect human rights under the UNGPs includes implementing a human rights due diligence process. Although the UNGPs do not provide guidance on the process for integrating women’s rights into human …


Acknowledging The Racist Roots Of Disinvestment And Abandonment: How Local Government Can Set The Stage For Change, Dana M. Malkus Jan 2022

Acknowledging The Racist Roots Of Disinvestment And Abandonment: How Local Government Can Set The Stage For Change, Dana M. Malkus

All Faculty Scholarship

Disinvestment and associated property abandonment are defining features of many post-industrial legacy cities. While the reasons are varied and complex, racist law and policy are at the root. Though abandoned properties negatively affect an entire city, their effects usually disproportionately fall on neighborhoods of color. Law and policy have been major drivers of how such neighborhoods look and feel today. Because law and policy have been part of the problem, they are also a necessary part of the solution.

This kind of large-scale, multi-disciplinary problem is beyond the ability of a single institution or sector to address. Stakeholders such as …


Protecting Patients From Physicians Who Inflict Harm: New Legal Resources For State Medical Boards, Elizabeth Pendo, Tristan Mcintosh, Heidi Walsh, Kari Baldwin, James M. Dubois Jan 2022

Protecting Patients From Physicians Who Inflict Harm: New Legal Resources For State Medical Boards, Elizabeth Pendo, Tristan Mcintosh, Heidi Walsh, Kari Baldwin, James M. Dubois

All Faculty Scholarship

State medical boards (SMBs) protect the public by ensuring that physicians uphold appropriate standards of care and ethical practice. Despite this clear purpose, egregious types of wrongdoing by physicians are alarmingly frequent, harmful, and under-reported. Even when egregious wrongdoing is reported to SMBs, it is unclear why SMBs sometimes fail to promptly remove seriously offending physicians from practice. Legal and policy tools that are targeted, well-informed, and actionable are urgently needed to help SMBs more effectively protect patients from egregious wrongdoing by physicians.

Past reviews of SMB performance have identified features of SMBs associated with higher rates of severe disciplinary …


Transition Barriers Of U.S. Military Veterans With Combat Occupations, Carole Thomas Jan 2022

Transition Barriers Of U.S. Military Veterans With Combat Occupations, Carole Thomas

Electronic Theses and Dissertations

Many combat-occupation veterans experience difficulty translating their military occupation to a civilian occupation after they leave the military. Veterans may struggle with military culture, self-leadership, health concerns, stereotypes, and employment barriers such as disability and underemployment. In this qualitative descriptive research study, the researcher analyzed the transition barriers U.S. combat-occupation veterans experienced when entering the civilian sector and workforce. The researcher interviewed six participants via Zoom using semistructured interview questions. All participants met the criteria of being 18–29 years old, being a veteran with a combat occupation, and having a willingness to tell their transition experiences. Five of the six …


Antisocial Personality Disorder: A Theoretical Approach Utilizing Three Dimensions Of Power Analysis, Timothy J. Nguyen, Tara Zolnikov Jan 2022

Antisocial Personality Disorder: A Theoretical Approach Utilizing Three Dimensions Of Power Analysis, Timothy J. Nguyen, Tara Zolnikov

Faculty Research, Scholarly, and Creative Activity

Antisocial Personality Disorder (ASPD) is often associated with high costs and burden to the rest of society; however, it remains a disorder with no evidence of effective traditional psychological interventions. This theoretical study aimed to analyze the phenomenon of power and how it may influence the conceptualization of ASPD. Data was collected through a comprehensive and systematic review of the current ASPD literature. Findings suggested ASPD as severely conceptually flawed, highly imbalanced in terms of power dynamics between professionals and people diagnosed with ASPD, absent of participants’ voices, absent of any effective traditional psychotherapy interventions, disproportionately focused on deficit-oriented strategies …


Blackcurrants: A Nutrient-Rich Source For The Development Of Functional Foods For Improved Athletic Performance, Ali Ali Redha, Shahida Anusha Siddiqui, Reza Zare, Daniele Spadaccini, Silvia Guazzotti, Xi Feng, Nur Alim Bahmid, Yuan Seng Wu, Fathima Zahraa Ozeer, Rotimi E. Aluko Jan 2022

Blackcurrants: A Nutrient-Rich Source For The Development Of Functional Foods For Improved Athletic Performance, Ali Ali Redha, Shahida Anusha Siddiqui, Reza Zare, Daniele Spadaccini, Silvia Guazzotti, Xi Feng, Nur Alim Bahmid, Yuan Seng Wu, Fathima Zahraa Ozeer, Rotimi E. Aluko

Faculty Research, Scholarly, and Creative Activity

Blackcurrants are nutrient-rich fruits with a significant amount of bioactive compounds including vitamin C and polyphenols, especially anthocyanins. The high phytochemical content of blackcurrants promotes this fruit to become a valuable functional food ingredient with varying health-promoting activities targeting different consumers including athletes. Athletes experience oxidative stress during intense exercise, which can result in inflammation and reduced exercise performance. Antioxidants such as vitamin C and polyphenols can restore the regular oxidative status of the body. Blackcurrant supplementation has shown potential ergogenic activity to improve athlete performance during high-intensity training. Clinical trials have evaluated the effectiveness of blackcurrant supplementation on exercise …


Abortion Attempts Without Clinical Supervision Among Transgender, Nonbinary And Gender-Expansive People In The United States, Heidi Moseson, Laura Fix, Caitlin Gerdts, Sachiko Ragosta, Jen Hastings, Ari Stoeffler, Eli A. Goldberg, Mitchell R. Lunn, Annesa Flentje, Matthew R. Capriotti, Micah E. Lubensky, Juno Obedin-Maliver Jan 2022

Abortion Attempts Without Clinical Supervision Among Transgender, Nonbinary And Gender-Expansive People In The United States, Heidi Moseson, Laura Fix, Caitlin Gerdts, Sachiko Ragosta, Jen Hastings, Ari Stoeffler, Eli A. Goldberg, Mitchell R. Lunn, Annesa Flentje, Matthew R. Capriotti, Micah E. Lubensky, Juno Obedin-Maliver

Faculty Research, Scholarly, and Creative Activity

Background Transgender, nonbinary and gender-expansive (TGE) people face barriers to abortion care and may consider abortion without clinical supervision. Methods In 2019, we recruited participants for an online survey about sexual and reproductive health. Eligible participants were TGE people assigned female or intersex at birth, 18 years and older, from across the United States, and recruited through The PRIDE Study or via online and in-person postings. Results Of 1694 TGE participants, 76 people (36% of those ever pregnant) reported considering trying to end a pregnancy on their own without clinical supervision, and a subset of these (n=40; 19% of those …


Leveraging Initial Cognitive Load To Predict User Response To Complex Visual Tasks, Reem Albaghli, Yaman Jandali, Sarah Almahmid, Nada Attar Jan 2022

Leveraging Initial Cognitive Load To Predict User Response To Complex Visual Tasks, Reem Albaghli, Yaman Jandali, Sarah Almahmid, Nada Attar

Faculty Research, Scholarly, and Creative Activity

In this study, we were able to show how cognitive load measurement during the initiation of a complex visual task can predict user response. We measured cognitive load using pupil size and microsaccade rate. The initial phase of task was defined as the first 25 percent of the trial Reaction Time (RT), which was variable up to 50 seconds. The complex visual task entailed a set of twelve words that could be grouped based into 1, 2, or 3 categories or sets, e.g., the words bed, pillow, headboard, etc. can be grouped into a single set that is bedroom. We …


Age As A Moderator Of Health Outcomes And Trust In Physicians And The Healthcare System, Emma Katz M.S. Jan 2022

Age As A Moderator Of Health Outcomes And Trust In Physicians And The Healthcare System, Emma Katz M.S.

Graduate Theses, Dissertations, and Problem Reports (ETD)

Trust is an integral part of the healthcare experience. Patient trust is associated with treatment adherence, patient satisfaction, patients engaging in follow-up care, shared decision-making, and positive health-related outcomes (e.g., Gupta et al., 2014; Mohseni & Lindstrom, 2007; Musa et al., 2009; Tam, 2012; Thom, et al., 2004; Trachtenberg et al., 2005). There are several levels of trust discussed in the literature, including interpersonal trust and institutional trust. The current study examined two levels of trust: interpersonal trust in the form of trust in the physician and institutional trust in the form of trust in the healthcare system. The study …


Statistical Abstract, Fiscal Year 2022, Tennessee. Department Of Correction Jan 2022

Statistical Abstract, Fiscal Year 2022, Tennessee. Department Of Correction

Annual Statistical Abstract

This document is the annual statistical report for the Tennessee Department of Correction during the fiscal year.


Stress-Associated Metabolites Vary With Both Season And Habitat Across Populations Of A Climate Sentinel Species, A. L. Whipple, C. Ray, J. Varner, J. N. Kitchens, A. A. Hove, J. A. Castillo Vardaro, J. L. Wilkening Jan 2022

Stress-Associated Metabolites Vary With Both Season And Habitat Across Populations Of A Climate Sentinel Species, A. L. Whipple, C. Ray, J. Varner, J. N. Kitchens, A. A. Hove, J. A. Castillo Vardaro, J. L. Wilkening

Faculty Research, Scholarly, and Creative Activity

Relating physiological stress to habitat quality could refine conservation efforts. Habitat quality, which is often inferred from patch occupancy or demographic rates, might be measured in a more timely and nuanced way using metrics of physiological stress. To understand whether stress-associated hormones vary with metrics of habitat quality, we measured fecal glucocorticoid metabolite (FGM) levels in the American pika (Ochotona princeps), a small mammal with well-defined habitat (talus), which can vary in quality depending on the presence of subsurface ice features. In spring and fall 2018, we collected feces noninvasively from pika territories in taluses “with” or “without” subsurface ice …


Nav1.1 Is Essential For Proprioceptive Signaling And Motor Behaviors, Cyrrus M. Espino, Cheyanne M. Lewis, Serena Ortiz, Miloni S. Dalal, Snigdha Garlapalli, Kaylee M. Wells, Darik A. O'Neil, Katherine A. Wilkinson, Theanne N. Griffith Jan 2022

Nav1.1 Is Essential For Proprioceptive Signaling And Motor Behaviors, Cyrrus M. Espino, Cheyanne M. Lewis, Serena Ortiz, Miloni S. Dalal, Snigdha Garlapalli, Kaylee M. Wells, Darik A. O'Neil, Katherine A. Wilkinson, Theanne N. Griffith

Faculty Research, Scholarly, and Creative Activity

The voltage-gated sodium channel (NaV), NaV1.1, is well-studied in the central nervous system; conversely, its contribution to peripheral sensory neuron function is more enigmatic. Here, we identify a new role for NaV1.1 in mammalian proprioception. RNAscope analysis and in vitro patch-clamp recordings in genetically identified mouse proprioceptors show ubiquitous channel expression and significant contributions to intrinsic excitability. Notably, genetic deletion of NaV1.1 in sensory neurons caused profound and visible motor coordination deficits in conditional knockout mice of both sexes, similar to conditional Piezo2-knockout animals, suggesting that this channel is a major contributor to sensory proprioceptive transmission. Ex vivo muscle afferent …


Control-Core: A Framework For Simulation And Design Of Closed-Loop Peripheral Neuromodulation Control Systems, Pradeeban Kathiravelu, Mark Arnold, Jake Fleischer, Yuyu Yao, Shubham Awasthi, Aviral Kumar Goel, Andrew Branen, Parisa Sarikhani, Gautam Kumar, Mayuresh V. Kothare, Babak Mahmoudi Jan 2022

Control-Core: A Framework For Simulation And Design Of Closed-Loop Peripheral Neuromodulation Control Systems, Pradeeban Kathiravelu, Mark Arnold, Jake Fleischer, Yuyu Yao, Shubham Awasthi, Aviral Kumar Goel, Andrew Branen, Parisa Sarikhani, Gautam Kumar, Mayuresh V. Kothare, Babak Mahmoudi

Faculty Research, Scholarly, and Creative Activity

Closed-loop Vagus Nerve Stimulation (VNS) based on physiological feedback signals is a promising approach to regulate organ functions and develop therapeutic devices. Designing closed-loop neurostimulation systems requires simulation environments and computing infrastructures that support i) modeling the physiological responses of organs under neuromodulation, also known as physiological models, and ii) the interaction between the physiological models and the neuromodulation control algorithms. However, existing simulation platforms do not support closed-loop VNS control systems modeling without extensive rewriting of computer code and manual deployment and configuration of programs. The CONTROL-CORE project aims to develop a flexible software platform for designing and implementing …


Implementation Of Aromatherapy By Occupational Therapists Can Reduce Pain, Tension, Stress For Patients With Intractable Pain In A Hospital Setting, Carlene Mull, Danielle Accordino Jan 2022

Implementation Of Aromatherapy By Occupational Therapists Can Reduce Pain, Tension, Stress For Patients With Intractable Pain In A Hospital Setting, Carlene Mull, Danielle Accordino

Department of Medicine

No abstract provided.