Digital Commons Network^™

Single-Cell Systems Neuroscience: A Growing Frontier In Mental Illness, Sean O'Sullivan

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

The development of effective treatments for psychiatric disease has been disappointing in recent decades given the advancements in neuroscience. Moreover, rising rates of mental illness such as addiction and depression compel scientists and physicians to discover novel and creative solutions. One such approach that has proven effective is systems neuroscience: A focus on networks as opposed to mechanism. Further, investigation at the single-cell and circuit level is likely to be fruitful in such endeavors as this resolution describes the functional psychopathology that allows for intervention.

Extracellular Matrix Guidance Of Autophagy: A Mechanism Regulating Cancer Growth, Carolyn Chen, Renato V. Iozzo

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

The extracellular matrix (ECM) exists as a dynamic network of biophysical and biochemical factors that maintain tissue homeostasis. Given its sensitivity to changes in the intra- and extracellular space, the plasticity of the ECM can be pathological in driving disease through aberrant matrix remodelling. In particular, cancer uses the matrix for its proliferation, angiogenesis, cellular reprogramming and metastatic spread. An emerging field of matrix biology focuses on proteoglycans that regulate autophagy, an intracellular process that plays both critical and contextual roles in cancer. Here, we review the most prominent autophagic modulators from the matrix and the current understanding of the …

Interferon Gamma Release Assay Mitogen Responses In Covid-19, Dagan Coppock, Claire E. Zurlo, Jenna M. Meloni, Sara L. Goss, John J. Zurlo, Matthew A. Pettengill

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Background

Elevated cytokine release and T cell exhaustion have been associated with COVID-19 disease severity. T cell activity may be indirectly measured through interferon gamma release assays (IGRAs), which use mitogen stimulation of T lymphocytes as a positive control. In our institution, an unexpectedly high rate of indeterminate IGRAs was noted in COVID-19–positive patients. We aimed to evaluate the clinical characteristics associated with indeterminate IGRA results and the difference in mitogen responses between COVID-19–positive and COVID-19–negative patients.

Methods

We reviewed all patients, regardless of COVID status, who were admitted between March 1, 2020, and May 31, 2020, and for whom …

A Study Of Information Needs Of Members Of Parliament Of India Related To Rural And Urban Development In Their Constituency, Dr Poonam Parashar, Dr Gareema Sharma, Dr Shailendra Kumar

Library Philosophy and Practice (e-journal)

The paper aims to analyze the information needs of Indian Members of Parliament (MPs) related to the rural and urban development in their constituency or region. Rural Connectivity is a key component of the rural development, thus the current study explores the level of awareness of Indian MPs about the status of rural connectivity with the Urban areas and rural accessibility via various means of Transport available for the people in their region/constituency for Intercity and Interstate Travel. The implementation of various Government schemes for the development of rural India by the Indian MPs has also been studied.

The data …

Availability And Utilization Of Ict Resources Inmanagement Of Students With Speical Needs In Academic Libraries In Enugu State, Calista Chinyere Aniekwe, Uzoamaka Ogwo Ph.D, Chinedu J. Ayolugbe

Library Philosophy and Practice (e-journal)

This study examined the utilization of ICT resources in the management of students with special needs in Enugu State, Nigeria. Two research questions and one hypothesis guided the study. Theoretical model of disability was adopted for the study. The study adopted a descriptive survey design. The population comprised of 200 students with special needs in selected universities in Enugu State. Simple random sampling technique was adopted in selecting 103 students with special needs in university libraries. The instrument for data collection was a structured questionnaire titled: Utilization of ICT Resources in the Management of Students with Special Needs Questionnaire (UICTRMSSNQ). …

A Scientometric Analysis Of Scientific Publications Related To Covid-19 In Library And Information Science Research, Zhahirah Indrawati Zainuddin, Safirotu Khoir

Library Philosophy and Practice (e-journal)

Purpose: As part of social sciences, Library and Information Science (LIS) has experienced development in COVID-19 discussions through the academic lens. The increasing number of research related to COVID-19 across subject areas is a response by researchers to overcome this crisis, including research in the LIS field. This research aims to describe the characteristics and trends of the keywords. It also aims to describe the most productive journals, institutions, and countries related to COVID-19 in LIS research.

Methods: We analysed 250 documents related to “COVID-19” in LIS research area indexed in Scopus during 2020-2022. VOSviewer was used to analyse the …

Investigation Of The Users’ Access To Health Information For Sustainable Development During The Covid 19 Era In Professor Kenneth Dike E-Central Library, Awka, Anambra State, Eliezer C. Agim, Maureen Azolo

Library Philosophy and Practice (e-journal)

The research investigated users’ access to health information for sustainable development during the Covid 19 era in Professor Kenneth Dike E-central Library, Awka, Anambra state. A descriptive survey research design was used for the study. The sample population comprised of 100 users of Professor Kenneth Dike E-central Library through the use of accidental sampling technique. A structured questionnaire was used for collection of data. The instrument was subjected to face validation and pilot test using Cronbach Alpha which gave a reliability coefficient value of 0.97. Data collected from the study were analyzed using mean scores. The study found that health …

Information Needs Assessment And The Usefulness Of Library Electronic Resources As Sources Of Critical Information, Patrick Ajibade Phd, Ndakasharwa Muchaonyerwa Phd

Library Philosophy and Practice (e-journal)

The ability to provide consistent and authoritative information during an emergency is crucial. Hence the role of libraries to curate online resources that is accessible during the pandemic is very important. This paper conducted an information needs assessment of the library’s electronic resources as sources of critical information. The pandemic was a pivotal moment for the libraries to serve as sources of valid reference sources and provide continued information. The paper conducted a qualitative assessment of 23 university students in order to understand their sources of critical information. Google's online survey platform was used to gather written interviews. The finding …

Documentation Of Nigerian Indigenous Knowledge System: The Role Of The Library, Christopher Agbeniaru Omigie Dr., Theresa Osasu Makinde Mrs., Ademola Victor Adeniran Mr.

Library Philosophy and Practice (e-journal)

This paper is on documentation of Nigerian indigenous knowledge system (IKS) as a national heritage through the role of the library as catalyst. The paper used literature analysis, recognizance survey and observations to explicitly describe the concept of IKS and its various sustainable ethos; it illustrates the components of the Nigerian IKS including the encompassed spiritual and physical sustainable elements that helps to promote its long time survival. Also treated in the paper are the relevance of IKS to the Nigerian national development; the challenges of IKS development in the country and the role of the library for sustainable collection …

Use Of Mobile Social Media For Academic Activities By Undergraduate Students At The Federal University Of Lafia, Nigeria, Alice Olije Odu, Madely Du Preez

Library Philosophy and Practice (e-journal)

In this article, we report on a phenomenological study that explored the use of mobile social media by 21 undergraduate students registered at the Federal University of Lafia, Nigeria, to support their academic-related information needs and activities. Furthermore, in the study, we attempted to acquire an understanding of why these students seem to prefer using their mobile devices and the ways in which their use of mobile devices affect their academic-related information seeking. Following an explanation of what social media entails, the discussion focused on the ways in which information-behaviour elements such as context, the user’s inner person and information …

Library Services And Challenges In State And Private University Libraries Of Gujarat: A Comparative Study, Somnath Ganeshnath Bava

Library Philosophy and Practice (e-journal)

The basic goal of all libraries is the satisfaction of patrons. Each and every library is to deliver the appropriate information to the right people at the right time. The user experience and the enhancement of the user's perception of libraries are both greatly influenced by libraries and their information offerings. When offering library services to patrons, librarians face a variety of difficulties. This study is presenting library and information services provided by state and private university libraries of Gujarat, the challenges and problems faced by the librarians during providing the best services to users. A researcher has discussed three …

Standardized Multi-Omics Of Earth’S Microbiomes Reveals Microbial And Metabolite Diversity, The Earth Microbiome Project 500 (Emp500) Consortium, Justin P. Shaffer, Louis Félix Nothias, Luke R. Thompson, Jon G. Sanders, Rodolfo A. Salido, Sneha P. Couvillion, Asker D. Brejnrod, Franck Lejzerowicz, Niina Haiminen, Shi Huang, Holly L. Lutz, Qiyun Zhu, Cameron Martino, James T. Morton, Smruthi Karthikeyan, Mélissa Nothias-Esposito, Kai Dührkop, Sebastian Böcker, Hyun Woo Kim, Alexander A. Aksenov, Wout Bittremieux, Jeremiah J. Minich, Clarisse Marotz, Mackenzie K.M. Bryant, Karenina Sanders, Tara Schwartz, Greg Humphrey, Yoshiki Vásquez-Baeza, Anupriya Tripathi

School of Biological and Marine Sciences

Despite advances in sequencing, lack of standardization makes comparisons across studies challenging and hampers insights into the structure and function of microbial communities across multiple habitats on a planetary scale. Here we present a multi-omics analysis of a diverse set of 880 microbial community samples collected for the Earth Microbiome Project. We include amplicon (16S, 18S, ITS) and shotgun metagenomic sequence data, and untargeted metabolomics data (liquid chromatography-tandem mass spectrometry and gas chromatography mass spectrometry). We used standardized protocols and analytical methods to characterize microbial communities, focusing on relationships and co-occurrences of microbially related metabolites and microbial taxa across environments, …

Students Patronage And Utilization Of Library And Information Resources; Evidence Of Afe Babalola University Ado Ekiti, Ekiti State, Nigeria., Adedara Judah T, Kolawole Idowu Oluwatola

Library Philosophy and Practice (e-journal)

The study investigated the student’s patronage and utilization of library and information resources in Afe Babalola University, Ado Ekiti, Ekiti State, Nigeria. Four research questions were considered to gather data. The sampled for the study comprised about 367 library patrons (Students). Purpose sampling the population of the study is techniques was adopted. The findings revealed that Afe Babalola University Library have enough materials which can help their patrons to achieve their aim such materials includes: abstract, dictionaries, directories, handbook, journals, projects, textbooks, report etc. Moreover, result showed that respondents visited library regularly but they visited library mostly to read for …

Assessment Of Preschool Librarians’ Library Disciplining Strategies For Effective Use Of Preschool Library, Charity C. Okeke M.Ed, Clara O. Ifelunni Phd, Anthonia N. Ngwoke Phd, Gloria C. Ugwu Phd, Eucharia N. Aye Phd, Chinedu I.O. Okeke Prof, Nnamdi T. Ekeanyanwu Prof, Christian S. Ugwuanyi Phd

Library Philosophy and Practice (e-journal)

Effective use of school libraries is very germane in achieving effective teaching and learning at various levels of education. Most importantly, the cultivation of the habit of using library by preschool children at the foundation phase will go a long way in patterning the reading habits of the children as they advance in their education. Currently, most preschool children exhibit unruly traits which are potential threats to effe3ctive management of preschool library. However, literature is scarce on the disciplining practices of the preschool Librarians for effective management of school library. Thus, this study was necessitated to explore the library disciplining …

Adoption Of Artificial Intelligence For Effective Library Service Delivery In Academic Libraries In Nigeria, Tunde Idris Yusuf, Odunola Adefunke Adebayo, Lateef Alhaji Bello, Joseph Olusegun Kayode

Library Philosophy and Practice (e-journal)

Due to the growing presence of artificial intelligence (AI) in developed countries, this paper looks at the adoption of artificial intelligence for effective library services in academic libraries in Nigeria. The paper describes the concept of artificial intelligence while tracing its origin. It further established the advantage of adopting artificial intelligence in academic libraries which include user-friendly, infinite functions, ability to take complex work among others; and the challenges faced by library management towards the adoption of artificial intelligence which include financial uncertainty, job loss, technological disadvantages among others. The paper concluded that the adoption of AI in academic libraries …

Application Of Wilson's Theory Of Information Seeking Behaviour To Public Library As A Source Of Business Information For Smes In Nigeria., Ugbala Chukwuemeka Peter, Lawal Olayide Wasiu, Olawale Gabrie Sola, Emmanuel Adeniyi Oloniruha, Fatokun Adesoji Musa

Library Philosophy and Practice (e-journal)

Business information has become a critical factor for the growth and success of small-scale business enterprises, the library as an institution responsible for information resources, sources and services to users, has indeed, become an indispensible partner in this national socio-economic growth and development drive. More typical however, is the public library because it is the only library that is open to every member of the public (SMEs owners inclusive) irrespective of background, age, status, race or creed. This paper therefore, discusses and provides useful insight on the application of Wilson’s theory of Information seeking behavioural to public library as a …

Pupils’ Experience With E-Learning During Covid-19 Lockdown In Delta State., Gloria Ogheneghatowho Oyovwe-Tinuoye Dr, Esharenana E. Adomi Prof

Library Philosophy and Practice (e-journal)

This study scrutinised pupils’ experience with e-learning during COVID-19 lockdown in Delta State. The study adopted a descriptive survey research design with five (5) research objectives of the study. The questionnaire was constructed after consultation of related literature to ensure that pertinent items were encompassed in it. A self-constructed questionnaire entitled “Pupils Experience with E-Learning during COVID- 19 Lockdown Questionnaire (PEELDC19LQ) was designed by the researchers. The population of the study comprised of all pupils in Delta State who participated in e-learning to meet up with the third curriculum and eventually used for promotion for the next class. The researchers …

Measuring Information Literacy Skills Of Mbbs Students, Imran Ali, Rashid Siddique, Khurram Shahzad

Library Philosophy and Practice (e-journal)

The main purpose of this study was to measure the information literacy skills of MBBS students at King Edward Medical University Lahore, Punjab Pakistan. The quantitative research method was used to carry out the study. A convenient sampling technique was used to collect data from the entire sample. The total number of respondents was 309 with a total response rate of 91.69%. SPSS 22^nd version was used to analyze the gathered data from respondents. Descriptive statistics were applied to check the frequency, percentage and reported in the form of tabulation. Moreover, the mean and standard deviation was also found …

Physical Work Environment And Job Satisfaction Of Library Personnel In Academic Libraries In Ogun State, Nigeria, Omolara Olufunmilayo Akinlade, Fredrick O. Ajegbomogun, Nancy Okorie Ph.D

Library Philosophy and Practice (e-journal)

Employee's job satisfaction is one of the primary factors that has been connected to the success of any organization. As a result, elements like promotions, remuneration, proper training, leadership styles, nature of work, perceived fairness and equality, coworker, and work environment all contribute to library personnel's job satisfaction. This study examined the influence of physical work environment on job satisfaction of library personnel in academic libraries in Ogun state, Nigeria. The population for this study includes the library personnel of nine academic libraries. Multistage sampling technique was used to select 170 respondents from nine academic libraries in Ogun State. Frequency …

Utilization Of Bibliotherapy Among Public Primary School English Language Teachers: Implications For Teaching Library Reading Skills, Gloria Chikasiemobi Ugwu Phd, Cajetan Ikechukwu Egbe Phd, Clara Odozi Ifelunni Phd

Library Philosophy and Practice (e-journal)

The study was conducted to find out the extent to which guidance counsellors are aware of bibliotherapy as a library reading skills intervention service, and the extent they utilize it in public primary schools in Nsukka Local Government Education Authority of Enugu State, Nigeria. Four research questions and two null hypotheses guided the study in line with the specific purposes of the study. Descriptive survey design was adopted for the study and population of 101 school guidance counsellors in the public primary schools were used for the study. The instrument for data collection was a questionnaire of 28 items which …

Library Services And Linked Data At Makerere University: Prospects Of A Research-Led University, Onan Mulumba

Library Philosophy and Practice (e-journal)

Makerere University is the oldest and most prestigious university in East Africa. As one of the best universities on the African content, Makerere is aligned to three main activities; Teaching, Research, and Community Outreach, and these are inclined to 5 core values; allegiance to the institution, integrity, customer responsiveness, professionalism, and openness to diversity. Makerere University has a library system, hosting both electronic and print resources. The digitization of print resources has created a system, through which delicate material is conserved. The files and their metadata, using Dublin Core, are stored in the institutional repository and in the integrated library …

Pivotal Role Of Information Communication Technology In Record And Archive Management, Marcus Aragabye, Oluwaseyi Awe, Mideenuhy Isiaq, Aisha Folarin, Abdullah Badmus, Shukurot Akorede, Adebukola Akinwale, Doocivir Annune

Library Philosophy and Practice (e-journal)

Record keeping is an ancient art that has survived in human activities for millennia, becoming ingrained in their everyday routines. Records that are well-maintained are an important element of an individual's or organization's memory. Many of the records are saved as event logs, transaction logs, and decision logs. The significance of preserving records, particularly when it comes to archiving them is largely concerned with managing the evidence of an organisation's actions as well as the reduction or mitigation of risk connected with it, and is part of an organisation's wider role of governance, risk management, and compliance (Tarantino, 2008).

Records …

Indigenisation Of Nigerian Librarianship Through Indigenous Knowledge: Exploring Its Possibilities, Abdulakeem Sodeeq Sulyman,, Basirat Omolara Amzat, Muritadho Abiodun Taiwo

Library Philosophy and Practice (e-journal)

Knowledge cannot be separated from the people holding it and the best way to make it appreciated is to present it in a way that represents the beliefs, customs and norms of its origin. This submission makes this paper attempts to find the perfect word between indigenisation and decolonisation as a way of developing Indigenous Librarianship in Nigeria. It settles for indigenisation because indigenisation focuses on the exploitation of the native, local resources to create, share, transform and retain knowledge. It ponders on the historical antecedents of Librarianship in Nigeria to proof that the Nigerian library practices were purely nurtured …

Perception And Contribution Of Librarians To Open Access Resources In Tertiary Institutions In Ekiti State, Nigeria, Fajiwe Olabode Thomas, Adedara Judah T

Library Philosophy and Practice (e-journal)

The study investigated the perception and contribution of Librarians to Open Access Resources in tertiary institutions in Ekiti State, Nigeria. The study adopted the expo-facto descriptive design. The sampled for the study comprised 100 Librarians who were randomly selected through simple random sampling. The Role of Librarians to Open Access Resources (RLOARs),Benefits Derived from Open Access Resources (BOARs) and Challenges encountered when promoting Open Access Resources (COARs) were the three instruments used to collect relevant data for the study. The research questions raised were answered using mean and standard deviation. Means scores cut off point of 2.50 and above would …

The Collaboration System Between Library Managers And Teachers During The Covid-19 Pandemic In Supporting Learning In Indonesia, Delia Annisa Lesmana, Pawit M. Yusup, Andri Yanto

Library Philosophy and Practice (e-journal)

The COVID-19 pandemic has impacted various aspects of life. One aspect affected is the educational aspect, where the learning process must be carried out through online learning. Given that online learning has never been implemented before, all available learning resources will significantly help schools achieve learning goals. The school library is the closest learning support source to provide a smooth online learning process. SDN Karya Mulya library implements collaboration between the library manager and teachers, especially in supporting student learning during the Covid-19 pandemic. This study aimed to determine the collaboration system between the library manager and SDN Karya Mulya …

Undergraduate History Students’ Attitude Towards University Library Services, Frances Jumoke Oloidi, Hero Usiomoefo Obasuyi, Ogechukwu Vivian Amanambu, Blessing Chisom Umeano

Library Philosophy and Practice (e-journal)

In institutions of higher learning, the library is at the forefront of information generation, acquisition, processing, organization, and dissemination. The services provided by the library contribute to staff, students, and institutional development. University library services serve as learning catalysts. Therefore, this study aimed to investigate undergraduate history students’ attitude towards university library services. A survey design was used for the study. A sample size of three hundred (300) undergraduate history students were conveniently selected. The data were analyzed using mean, standard deviation, and f-test. The findings showed that undergraduate history students’ attitude towards university library services was positive. The undergraduate …

Evaluating The Effectiveness Of Internet Library Resources On Students’ Achievement In Physics, Christian S. Ugwuanyi Phd

Library Philosophy and Practice (e-journal)

Because the face-to-face form of learning was temporarily suspended at the start of the pandemic, the way learners learned prior to the appearance of coronavirus 2019 (Covid-19) was severely impacted. When the pandemic was at its worst, most developed countries switched to online education, while most developing countries' schools were shut down entirely. A lack of web resources in those developing countries was one of the reasons for this. Internet library resources have been found to have the potential to improve teaching and learning, according to the literature. However, no empirical research has been done in Nigeria to examine the …

Sources Of Library Information Needs For Climate Change Adaptation Among Rural Farmers In South Eastern Nigeria, Abaobi David Agbo Phd, Christian Sunday Ugwuanyi Phd, Onyinye Regina Ekere Mrs

Library Philosophy and Practice (e-journal)

There is a dearth of research on the library information needs of farmers for climate change adaptation to improve agricultural products among the rural farmers. Thus, this study explored the sources of library information needs for climate change adaption among rural farmers. Descriptive survey research was adopted for the study using a sample of 510 registered rural farmers in South Eastern Nigeria. A well validated and trial tested instrument was used to collect the data. The internal consistency reliability index of the instrument was 0.97 using Cronbach alpha method. Data collected were analysed using mean as a descriptive statistic to …

Relationship Between Entrepreneurial Self-Efficacy And Entrepreneurial Intention In Medical Library And Information Science Students: An Iranian Perspective, Ronak Hamzehei, Mohammad Karim Saberi, Zahra Moradi, Zhaleh Moradveysi, Mahdi Shaghaghi

Library Philosophy and Practice (e-journal)

Purpose: The main purpose of this study is to investigate the relationship between entrepreneurial self-efficacy and entrepreneurial intention of students in the field of medical library and information science.

Methods: This study quantitatively examined seven hypotheses through Structural Equation Modeling (SEM) techniques. Using the census method, 79 students of medical library and information science of Hamadan University of Medical Sciences, Iran, were studied. Data was collected using the Entrepreneurial Self-efficacy Questionnaire proposed by De Noble et al. (1999) and the Entrepreneurial Intention Questionnaire presented by the Linan and Chen (2011). Descriptive and inferential data analysis was performed using SPSS and …

Electronic Health (E-Health) Literacy Among Undergraduate University Students, Kalsoom Akhtar, Shazia Yusuf Dr, Samar Fahd Dr, Imran Ajmal

Library Philosophy and Practice (e-journal)

E-health literacy refers to the knowledge of electronic resources and searching techniques that are required to obtain credible health information. E-health literacy can help the general population to search, acquire, appraise, use and interpret health-related information from electronic sources, as well as to be able to apply the gained information to address and solve health-related problems.

A large scale cross-sectional survey was conducted to appraise the e-health literacy skills among undergraduate psychology students. The population of the study comprised of undergraduate psychology students enrolled in the public sector universities. A questionnaire was developed by conducting a thorough review of the …