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2022

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Effects Of Replacing The Protein Content Of Azolla Pinnata With Concentrate On Physiological And Blood Profiles Changes In Sahiwal Calves, Ninad Bhatt, Ramesh Chandra, Kotresh Prasad Chikkagoudara, Diksha Kandpal, Deepesh Bharat Misra, Nitin Tyagi Jan 2022

Effects Of Replacing The Protein Content Of Azolla Pinnata With Concentrate On Physiological And Blood Profiles Changes In Sahiwal Calves, Ninad Bhatt, Ramesh Chandra, Kotresh Prasad Chikkagoudara, Diksha Kandpal, Deepesh Bharat Misra, Nitin Tyagi

Turkish Journal of Veterinary & Animal Sciences

Eighteen female Sahiwal calves of average four month of age and 54 kg body weight were selected for the study. The animals were divided into three groups (T0, T1, and T2) on body weight basis. The animals were fed as per ICAR feeding standard (2013) for calves for 90 days. The animals in T0 group T0 were fed as per feeding standard while in T1 and T2 groups, fresh Azolla pinnata was fed by replacing 15% and 30% protein content of concentrate with Azolla pinnata on DM basis. The nonsignificant results were obtained for all the physiological parameters. In addition, …

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Effect Of Nonfiber Carbohydrate And Crude Protein Levels In The Formula Of Feed On In Vitro Rumen Fermentation Characteristics And Growth Performance Of Weaned Hanwoo Calves, Jun Sang Ahn, Byung Ki Park Jan 2022

Effect Of Nonfiber Carbohydrate And Crude Protein Levels In The Formula Of Feed On In Vitro Rumen Fermentation Characteristics And Growth Performance Of Weaned Hanwoo Calves, Jun Sang Ahn, Byung Ki Park

Turkish Journal of Veterinary & Animal Sciences

This study was conducted to determine the effect of nonfiber carbohydrates (NFC) and crude protein (CP) present in formula feed on the rumen fermentation characteristics and growth performance of weaned Hanwoo calves. Forty weaned calves were randomly assigned to four dietary groups based on NFC and CP levels as follows: high NFC (HN) at 38%-42%, low NFC (LN) at 33%-36%, high CP (HP) at 25%-26%, and low CP (LP) at 23%-24%. These groups were categorized as HN-HP, HN-LP, LN-HP, and LN-LP groups. Total digestible nutrients (TDN) and CP levels did not significantly affect the in vitro ruminal total gas, propionate, …

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Cryopreservation Of Nili-Ravi Buffalo Bull Semen: Yearly Postthaw Analyses To Depict Climatic Effects, Ejaz Ahmad, Muhammad Shakeel, Zahid Naseer, Adeel Ahmed, Mudussar Nawaz, Muhammad Saleem Akhtar Jan 2022

Cryopreservation Of Nili-Ravi Buffalo Bull Semen: Yearly Postthaw Analyses To Depict Climatic Effects, Ejaz Ahmad, Muhammad Shakeel, Zahid Naseer, Adeel Ahmed, Mudussar Nawaz, Muhammad Saleem Akhtar

Turkish Journal of Veterinary & Animal Sciences

The present study was aimed to observe the postthaw quality of Nili-Ravi buffalo bull semen cryopreserved during heat stress (hot summer months) and normal climatic conditions (fall, winter, and spring months). For this purpose, four (n = 4) adult regular donor Nili-Ravi buffalo bulls were selected to collect and cryopreserve their semen throughout the period of an entire year. The cryopreservation of semen was done following standard freezing protocol. The semen doses cryopreserved during heat stress and normal climatic condition were thawed to determine the sperm motility, motion kinetics, viability, plasma membrane integrity, acrosomal integrity, and morphological abnormalities (head, mid-piece, …

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Detection Of Correct Pregnancy Status In Lactating Dairy Cattle Using Mars Data Mining Algorithm, Demet Çanga, Mustafa Boğa Jan 2022

Detection Of Correct Pregnancy Status In Lactating Dairy Cattle Using Mars Data Mining Algorithm, Demet Çanga, Mustafa Boğa

Turkish Journal of Veterinary & Animal Sciences

In this study, it is aimed to determine pregnancy outcomes by using multivariate adaptive regression splines (MARS) algorithm for classification type problems. For this purpose, data obtained from a private dairy farm in the Konya region of Türkiye in 2020 were used to determine pregnancy outcomes in Holstein dairy cattle. It has been determined how to perform statistical analyses on solving classification-type problems with the MARS algorithm and how to use R packages (caret and earth) by creating an R script file. After the analysis, the MARS estimation equation was created and in finding the probability of being pregnant: While …

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Determination Of Colony Characteristics And Suitability For Mass Production Of Native Bombus Terrestris L. Population In The Central Black Sea Coast Region, Sali̇m Aktürk, Ayhan Gösteri̇t, Gökhan Akdeni̇z, Samet Okuyan, Ahmet Emi̇r Şahi̇n Jan 2022

Determination Of Colony Characteristics And Suitability For Mass Production Of Native Bombus Terrestris L. Population In The Central Black Sea Coast Region, Sali̇m Aktürk, Ayhan Gösteri̇t, Gökhan Akdeni̇z, Samet Okuyan, Ahmet Emi̇r Şahi̇n

Turkish Journal of Veterinary & Animal Sciences

In this study, two successive generations of queens belonging to a native Bombus terrestris population in the Central Black Sea Region of Türkiye were reared under controlled laboratory conditions to examine its developmental characteristics and suitability for mass production. The first generation was formed by a hundred Bombus terrestris queens which were caught from native fauna in Ordu Province, Türkiye. Young queens and males produced at the end of the life cycle in different colonies of first generation were mated in laboratory conditions. Mated queens were placed in a refrigerated incubator for their two months diapause period. After the diapause …

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Investigation Of Antimicrobial Resistance Of Esßl, Amp-C, And Carbapenemaseproducing E. Coli Strains In Retail Poultry Meats, Gülçi̇n Güven, Si̇bel Kizil Jan 2022

Investigation Of Antimicrobial Resistance Of Esßl, Amp-C, And Carbapenemaseproducing E. Coli Strains In Retail Poultry Meats, Gülçi̇n Güven, Si̇bel Kizil

Turkish Journal of Veterinary & Animal Sciences

Antimicrobial agents are used for suppressing some bacterial infections during the rearing of poultry. In this study; the antibiotic resistance properties of Extended Spectrum ßeta-lactamase (ESßL), Amp-C, carbapenemase-producing Escherichia coli (E. coli) strains isolated from chicken breast meat were determined by disc diffusion and E-test methods. Additionally, it is aimed to determine antibiotic resistance genes by classical polymerase chain reaction (PCR). In this context, E. coli strains were isolated from 7 of 100 chicken breast meat (fillets) and identified by a rapid identification system (BBL Crystal). Disc diffusion test results of the isolates were evaluated and 100% to tetracycline; ampicillin, …

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Typing Of Rarely Isolated Salmonella Serotypes With Mlst, Seyyi̇de Sariçam İnce, İnci̇ Başak Müştak, Hami̇t Kaan Müştak Jan 2022

Typing Of Rarely Isolated Salmonella Serotypes With Mlst, Seyyi̇de Sariçam İnce, İnci̇ Başak Müştak, Hami̇t Kaan Müştak

Turkish Journal of Veterinary & Animal Sciences

Salmonellosis caused by nontyphoidal Salmonella is the second most common zoonotic infection worldwide. The major foodborne route of this infection is the consumption of contaminated poultry meat and egg. Therefore, monitoring and control of Salmonella agents in poultry populations is critical to reduce the risks for public health. In the poultry industry, the most common serotypes in Salmonella infections are Salmonella enterica subsp. enterica serotype Enteritidis and Typhimurium. In recent years, other frequently isolated Salmonella serotypes have also increased in Turkey because of the Salmonella control programs regulated by many countries. Hence, other Salmonella serotypes (except for the most frequently …

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2021-22 Annual Report, Tennessee. Board Of Paroles Jan 2022

2021-22 Annual Report, Tennessee. Board Of Paroles

Annual Reports

This document is the annual report for the Tennessee Board of Parole during the fiscal year.

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Reflux, Dysphonia, And Dysphagia Symptoms In Patients With Diabetes And Their Association With Diabetic Complications, Hakan Gölaç, Güzi̇de Atalik, Yusuf Kemal Kemaloğlu, Meti̇n Yilmaz Jan 2022

Reflux, Dysphonia, And Dysphagia Symptoms In Patients With Diabetes And Their Association With Diabetic Complications, Hakan Gölaç, Güzi̇de Atalik, Yusuf Kemal Kemaloğlu, Meti̇n Yilmaz

Turkish Journal of Medical Sciences

No abstract provided.

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Evaluation Of Anthropometric Measurements And Clinical Tests In The Diagnosis Of Difficult Airway In Patients Undergoing Head And Neck Surgery, Şükrü Mert Başpinar, İlkben Günüşen, Demet Sergi̇n, Asuman Sargin, Saci̇tti̇n Taner Balcioğlu Jan 2022

Evaluation Of Anthropometric Measurements And Clinical Tests In The Diagnosis Of Difficult Airway In Patients Undergoing Head And Neck Surgery, Şükrü Mert Başpinar, İlkben Günüşen, Demet Sergi̇n, Asuman Sargin, Saci̇tti̇n Taner Balcioğlu

Turkish Journal of Medical Sciences

No abstract provided.

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Conservative Management Of Patients With Endometrial Intraepithelial Neoplasia (Ein): Factors That Could Affect Response And Pregnancy Rates., Christos Iavazzo, Ioannis Gkegkes Jan 2022

Conservative Management Of Patients With Endometrial Intraepithelial Neoplasia (Ein): Factors That Could Affect Response And Pregnancy Rates., Christos Iavazzo, Ioannis Gkegkes

Turkish Journal of Medical Sciences

No abstract provided.

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Cover And Contents Jan 2022

Cover And Contents

Turkish Journal of Medical Sciences

No abstract provided.

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Evidence-Based Information About Intermittent Fasting In Diabetes Patients: Useful Or Harmful?, Mustafa Altay Jan 2022

Evidence-Based Information About Intermittent Fasting In Diabetes Patients: Useful Or Harmful?, Mustafa Altay

Turkish Journal of Medical Sciences

Background/aim: One of the most important components of treatment for diabetic patients is diet and healthy nutrition therapy. Calorie restriction is effective and without cost increases its appeal for both patients and physicians. Unfortunately, continuous calorie restriction is a difficult method. For this reason, alternative calorie restriction methods, such as intermittent fasting (IF), have been investigated by some researchers. Materials and methods: IF refers to a wide range of diet programmes covering periods of eating and fasting, which vary according to the different regimens. In this article, first, some general information will enable us to understand the concept of IF, …

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Determination Of Cardiovascular Risk In 192,711 Underweight And Normal Weight Workers, Bárbara Altisench Jané, José Ignacio Ramírez Manent, Sebastiana Arroyo Bote, Pere Riutord Sbert, Hilda María González San Miguel, Angel Arturo Lopez Gonzalez Jan 2022

Determination Of Cardiovascular Risk In 192,711 Underweight And Normal Weight Workers, Bárbara Altisench Jané, José Ignacio Ramírez Manent, Sebastiana Arroyo Bote, Pere Riutord Sbert, Hilda María González San Miguel, Angel Arturo Lopez Gonzalez

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to determine the prevalence of cardiovascular risk factors (CVRF) and the level of cardiovascular risk (CVR), determined with different scales (REGICOR, SCORE, ERICE, vascular age...) in people with low and normal weight. Materials and Methods: A total of 192,711 underweight and normal weight Spanish workers participated. CVR parameters included were weight, abdominal circumference, blood pressure, glycemia (high >125 mg/dL or under hypoglycemic treatment) and lipids (cutoff points: total cholesterol 200 mg/dL, LDL 130 mg/dL, triglycerides 150 mg/dL) were obtained by automated enzymatic methods. Body mass index (BMI) was calculated, considering underweight 18.5 and …

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Covid-19 Course In Granulomatosis With Polyangiitis: Single Center Experience With Review Of The Literature, Berkan Armağan, Mehmet Aki̇f Eksi̇n, Serdar Can Güven, Bahar Özdemi̇r, Pinar Akyüz Dağli, Orhan Küçükşahi̇n, Ahmet Omma, Abdulsamet Erden Jan 2022

Covid-19 Course In Granulomatosis With Polyangiitis: Single Center Experience With Review Of The Literature, Berkan Armağan, Mehmet Aki̇f Eksi̇n, Serdar Can Güven, Bahar Özdemi̇r, Pinar Akyüz Dağli, Orhan Küçükşahi̇n, Ahmet Omma, Abdulsamet Erden

Turkish Journal of Medical Sciences

Background/aim: Coronavirus disease 2019 (COVID-19) shares some clinical features with new-onset granulomatosis with polyangiitis (GPA) or GPA flare that may lead to a challenge in differential diagnosis. To date, little is known whether GPA can be induced by COVID-19. Herein, we aimed to seek the frequency and mortality rates of COVID-19 in our GPA cohort, and along with the literature cases, to evaluate clinical features and treatments of GPA patients with COVID-19. We also tried to identify clinical features of COVID-19 induced GPA. Materials and methods: As of July 2021, we conducted a systematic literature review using different spelling combinations …

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The Neurodevelopmental Profile Of Healthy Children With Premature Anterior Fontanel Closure, Meltem Di̇rek, Khatuna Makharoblidze, Burçi̇n Gönüllü Polat, Asena Ayça Özdemi̇r, Çeti̇n Okuyaz Jan 2022

The Neurodevelopmental Profile Of Healthy Children With Premature Anterior Fontanel Closure, Meltem Di̇rek, Khatuna Makharoblidze, Burçi̇n Gönüllü Polat, Asena Ayça Özdemi̇r, Çeti̇n Okuyaz

Turkish Journal of Medical Sciences

Background/aim: We aimed to assess the neurodevelopmental status of healthy children with premature anterior fontanel closure. Materials and methods: This retrospective observational study was conducted on 40 (20 M, 20 F) children admitted to Mersin University Pediatric Neurology Outpatient Clinic between 2015-2020 with complaints of premature fontanel closure. Patients with dysmorphic features, microcephaly, craniosynostosis, hypoxic-ischemic sequelae, infections, metabolic disorders, intracranial hemorrhage, epilepsy, endocrine problems, additional congenital anomalies, intrauterine growth retardation (IUGR), prematurity, and postmaturity were excluded. The Denver II and Bayley III tests were applied to all patients and controls. Results: The Denver II identified retardations in gross motor skills …

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Rivaroxaban And Apixaban In Patients With Atrial Fibrillation; A Real-World Data, Onur Aslan, Si̇nan Yildirim Jan 2022

Rivaroxaban And Apixaban In Patients With Atrial Fibrillation; A Real-World Data, Onur Aslan, Si̇nan Yildirim

Turkish Journal of Medical Sciences

Background/aim: This study aims to analyze the real-life data of patients who were prescribed rivaroxaban and apixaban and to emphasize the points that we think will make a difference compared to randomized controlled studies. Materials and methods: The patients who accepted to participate in the study in whom rivaroxaban (15-20 mg) and apixaban (2.5-5 mg) were started with the diagnosis of atrial fibrillation between 01 January 2018 and 31 December 2019 and whose records were fully accessed through the hospital automation system were included in the study. Results: One hundred and ninety-four (48.5%) of a total of 400 patients using …

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Investigation Of Cochlear Microphonics Recorded With Different Stimulus Types, Özgecan Güneşer, Ayşe Arzu Yi̇ği̇t, Asuman Alniaçik, Kürşat Yanarateş, Eda Çakmak Jan 2022

Investigation Of Cochlear Microphonics Recorded With Different Stimulus Types, Özgecan Güneşer, Ayşe Arzu Yi̇ği̇t, Asuman Alniaçik, Kürşat Yanarateş, Eda Çakmak

Turkish Journal of Medical Sciences

Background/aim: Electrocochleography (ECochG), one of the first defined tests under auditory evoked potentials, is a total electrical response of inner and outer hair cells inside the cochlea and auditory nerve record technique to the presence of an acoustic stimulus. T hese records can be used in Meniere disease and auditory neuropathy spectrum disorder diagnosis, intraoperative monitoring. In addition, the presence of cochlear microphonics plays a crucial role in auditory neuropathy spectrum disorder diagnosis. In our study, healthy individuals were tested with extratimpanic electrocochleography record method via Click and LS CE-Chirp stimulus, and the results were compared to the age, sex, …

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Use Of Ultrasonography In Confirming The Malposition Of The I-Gel In Pediatric Patients: A Prospective Observational Study, Faruk Çi̇çekci̇, Mehmet Selçuk Uluer, Mehmet Sargin, Emi̇ne Aslanlar, İnci̇ Kara, Muslu Kazim Körez Jan 2022

Use Of Ultrasonography In Confirming The Malposition Of The I-Gel In Pediatric Patients: A Prospective Observational Study, Faruk Çi̇çekci̇, Mehmet Selçuk Uluer, Mehmet Sargin, Emi̇ne Aslanlar, İnci̇ Kara, Muslu Kazim Körez

Turkish Journal of Medical Sciences

Background/aim: This study was designed to observe and compare the performance of fiberoptic laryngeal (FOL) view, leakage test (LT) and ultrasonography (USG) usage in detecting i-gel position in pediatric patients. Materials and methods: One hundred ten consecutive children were included in this single-armed prospective observational study. After anesthetic induction, i-gel placement confirmed using FOL and LT was evaluated using USG in three planes. According to our scoring system, acceptable and unacceptable grades (FOL, LT and USG) were determined to describe placement. Sensitivity and specificity were determined by comparing USG performance with the other two tests. Results: Ultrasonography was found a …

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New Parameters On Prediction Of Severity Of Transient Tachypnea Of The Newborn, Yusuf Çeli̇k, Di̇lek Kahveci̇oğlu, İbrahi̇m Ece, Fati̇h Ati̇k, Aslihan Köse Çeti̇nkaya, Medi̇ne Ayşi̇n Taşar Jan 2022

New Parameters On Prediction Of Severity Of Transient Tachypnea Of The Newborn, Yusuf Çeli̇k, Di̇lek Kahveci̇oğlu, İbrahi̇m Ece, Fati̇h Ati̇k, Aslihan Köse Çeti̇nkaya, Medi̇ne Ayşi̇n Taşar

Turkish Journal of Medical Sciences

Background/aim: Transient tachypnea of the newborn (TTN) is a common clinical problem that often occurs in the first hours of life. Although it is considered to be a benign clinical course, some cases may have severe symptoms and require ventilation support. In this study, we aimed to determine the association between the mean platelet volume (MPV), nucleated red blood cells (NRBCs), right ventricular systolic pressure (RVSP), and the severity of TTN. Materials and methods: Patients with TTN were divided into two groups according to Silverman score (

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Nucleolus Assessment In Invasive Breast Carcinoma, An Objective Parameter For Histological Grading, Seda Duman Öztürk, Çi̇ğdem Öztürk, Oğuzhan Okcu, Bayram Şen, Recep Bedi̇r Jan 2022

Nucleolus Assessment In Invasive Breast Carcinoma, An Objective Parameter For Histological Grading, Seda Duman Öztürk, Çi̇ğdem Öztürk, Oğuzhan Okcu, Bayram Şen, Recep Bedi̇r

Turkish Journal of Medical Sciences

Background/aim: The nucleolus has the potential to provide insight into how many types of cancer will progress. In this study, we examined the evaluation of the nucleolus with a microscope in widespread breast cancer tumors and whether this value contributes to tumor grading as an objective clinicopathological parameter. Materials and methods: In our study, the nucleolus was evaluated retrospectively in resections with a diagnosis of invasive breast carcinoma of the cases between January 2010 and April 2021. In total, the tumor nucleolus of 377 cases of invasive breast carcinoma was evaluated. Nucleolus evaluation was performed with light microscopy using four …

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The Role Of Vitamin D-Synthesizing Enzyme Cyp27b1 In Systemic Lupus Erythematosus, Man Luo, Jing Liu, Yeshuang Yuan, Yong Chen, Guohua Yuan Jan 2022

The Role Of Vitamin D-Synthesizing Enzyme Cyp27b1 In Systemic Lupus Erythematosus, Man Luo, Jing Liu, Yeshuang Yuan, Yong Chen, Guohua Yuan

Turkish Journal of Medical Sciences

Background/aim: To measure the expression of 1α-hydroxylase (CYP27B1) and serum 25(OH)D concentration in systemic lupus erythematosus (SLE) and to investigate the role of CYP27B1 in SLE. Materials and methods: Seventy-seven SLE patients and 35 healthy controls (HCs) were enrolled from September 2017 to January 2020. T he study design is cross-sectional. mRNA expression of CYP27B1 in peripheral blood mononuclear cells (PBMCs) was measured by reverse-transcription quantitative PCR, the protein level of CYP27B1 was quantified by western blotting, and the serum level of 25(OH) D was determined by an enzyme-linked immunosorbent assay. Results: The mRNA expression of CYP27B1 in PBMCs was …

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Prognostic Factors Of Perioperative Flot Regimen In Operable Gastric And Gastroesophageal Junction Tumors: Real-Life Data (Turkish Oncology Group), Ci̇han Erol, Abdullah Saki̇n, Tuğba Başoğlu Tüylü, Ercan Özden, Devri̇m Çabuk, Mutlu Doğan, Ömür Berna Çakmak Öksüzoğlu, Hasan Çağri Yildirim, İrem Öner, Melek Karakurt Eryilmaz, Özgecan Dülgar, Di̇nçer Aydin, Nesli̇han Özyurt, Mi̇raç Özen, İlhan Hacibeki̇roğlu Jan 2022

Prognostic Factors Of Perioperative Flot Regimen In Operable Gastric And Gastroesophageal Junction Tumors: Real-Life Data (Turkish Oncology Group), Ci̇han Erol, Abdullah Saki̇n, Tuğba Başoğlu Tüylü, Ercan Özden, Devri̇m Çabuk, Mutlu Doğan, Ömür Berna Çakmak Öksüzoğlu, Hasan Çağri Yildirim, İrem Öner, Melek Karakurt Eryilmaz, Özgecan Dülgar, Di̇nçer Aydin, Nesli̇han Özyurt, Mi̇raç Özen, İlhan Hacibeki̇roğlu

Turkish Journal of Medical Sciences

Background/aim: Perioperative FLOT regimen is a standard of care in locally advanced operable gastric and GEJ adenocarcinoma. We aimed to determine the efficacy, prognostic factors of perioperative FLOT chemotherapy in real-life gastric and GEJ tumors. Materials and methods: The data of patients who were treated with perioperative FLOT chemotherapy were retrospectively analyzed from 34 different oncology centers in Turkey. Baseline clinical and demographic characteristics, pretreatment laboratory values, histological and molecular characteristics were recorded. Results: A total of 441 patients were included in the study. The median of age our study population was 60 years. The majority of patients with radiological …

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Evaluation Of Subclinical Cardiovascular Disease By Carotid Intima Media Thickness, Epicardial Adipose Tissue Thickness, Serum Endocan, And Nesfatin-1 Levels In Patients With Primary Hyperparathyroidism, Muhammet Kocabaş, Yakup Alsancak, Mustafa Can, İlker Çordan, Hati̇ce Çalişkan Burgucu, Meli̇a Karaköse, Fatma Hümeyra Yerli̇kaya, Mustafa Kulaksizoğlu, Feri̇dun Karakurt Jan 2022

Evaluation Of Subclinical Cardiovascular Disease By Carotid Intima Media Thickness, Epicardial Adipose Tissue Thickness, Serum Endocan, And Nesfatin-1 Levels In Patients With Primary Hyperparathyroidism, Muhammet Kocabaş, Yakup Alsancak, Mustafa Can, İlker Çordan, Hati̇ce Çalişkan Burgucu, Meli̇a Karaköse, Fatma Hümeyra Yerli̇kaya, Mustafa Kulaksizoğlu, Feri̇dun Karakurt

Turkish Journal of Medical Sciences

Background/aim: Data on the presence and extent of cardiovascular disease (CVD) risk in primary hyperparathyroidism (PHPT) are conflicting. In our study, we aimed to investigate the increased CVD risk in patients with PHPT by carotid intima-media thickness (CIMT), epicardial adipose tissue (EAT) thickness, and serum levels of endocan and nesfatin-1. Materials and methods: Patients with PHPT (n = 44) and age- and sex-matched healthy control subjects (n = 40) were enrolled in this study. Demographic data of the participants were questioned. Serum endocan and nesfatin-1 concentrations were assessed using commercially available ELISA kits. Noninvasive measurements of CIMT and EAT thickness …

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Association Of Thiol/Disulphide Homeostasis With Bethesda Classification Of Thyroid Nodules And Thyroid Cancer, Muhammet Cüneyt Bi̇lgi̇ner, Abbas Ali̇ Tam, Sevgül Faki, Bağdagül Yüksel Güler, Özcan Erel, İbrahi̇m Kilinç, Di̇dem Özdemi̇r, Oya Topaloğlu, Reyhan Ersoy, Beki̇r Çakir Jan 2022

Association Of Thiol/Disulphide Homeostasis With Bethesda Classification Of Thyroid Nodules And Thyroid Cancer, Muhammet Cüneyt Bi̇lgi̇ner, Abbas Ali̇ Tam, Sevgül Faki, Bağdagül Yüksel Güler, Özcan Erel, İbrahi̇m Kilinç, Di̇dem Özdemi̇r, Oya Topaloğlu, Reyhan Ersoy, Beki̇r Çakir

Turkish Journal of Medical Sciences

Background/aim: Ultrasonography and fine-needle aspiration biopsy are frequently used to diagnose thyroid cancer. However, supportive data might be required in case of diagnostic difficulty. This study investigated whether there is a relationship between thiol/ disulphide homeostasis and cytological and histopathological diagnosis of thyroid nodules. Materials and methods: The patient group consisted of 81 individuals with euthyroid nodular (single/multiple) goiter scheduled for thyroidectomy, and the control group consisted of 28 age- and sex-matched healthy volunteers who had no thyroid nodule on ultrasonographic evaluation. All participants were selected among the admissions to the study clinic between June 2017 and June 2018, and …

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The Correlation Of Serum Spd-1 And Spd-L1 Levels With Clinical, Pathological Characteristics And Lymph Node Metastasis In Nonsmall Cell Lung Cancer Patients, Burcu Ancin, Mesut Meli̇h Özercan, Yi̇ği̇t Yilmaz, Serkan Uysal, Ulaş Kumbasar, Zeynep Saribaş, Erkan Di̇kmen, Riza Doğan, Meti̇n Demi̇rci̇n Jan 2022

The Correlation Of Serum Spd-1 And Spd-L1 Levels With Clinical, Pathological Characteristics And Lymph Node Metastasis In Nonsmall Cell Lung Cancer Patients, Burcu Ancin, Mesut Meli̇h Özercan, Yi̇ği̇t Yilmaz, Serkan Uysal, Ulaş Kumbasar, Zeynep Saribaş, Erkan Di̇kmen, Riza Doğan, Meti̇n Demi̇rci̇n

Turkish Journal of Medical Sciences

Background/aim: Significant advances have been achieved in immunotherapy for the treatment of lung cancer. It is known that tumor cells and cells in the tumor microenvironment express high amounts of programmed cell death ligand 1 (PD-L1). These PD-L1s interact with programmed cell death protein 1 (PD-1), causing immunosuppression. The aim of our study is to examine the correlation between the serum sPD-1 and sPD-L1 levels and clinicopathological characteristics in patients with nonsmall cell lung cancer. We also compared our results with the healthy population (control group). Materials and methods: Thirthy-seven nonsmall cell lung cancer (NSCLC) patients who were operated in …

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The Effect Of Immunonutrition On Tumor Infiltrative T Lymphocytes And Regulatory T Cells In Rectal Tumor Patients Receiving Neoadjuvant Chemoradiotherapy: A Prospective Randomized Clinical Study, Mehmet Onur Gül, Cebrai̇l Akyüz, Selvi̇naz Özkara Jan 2022

The Effect Of Immunonutrition On Tumor Infiltrative T Lymphocytes And Regulatory T Cells In Rectal Tumor Patients Receiving Neoadjuvant Chemoradiotherapy: A Prospective Randomized Clinical Study, Mehmet Onur Gül, Cebrai̇l Akyüz, Selvi̇naz Özkara

Turkish Journal of Medical Sciences

Background/aim: The rationale behind using immunonutrition in cancer patients is to prevent malnutrition, manage the host's immune response, and keep cancer under control by utilizing the potential immune system available in the host against the tumor. This prospective- study aims to assess the impact of immunonutrition on tumor-infiltrating lymphocytes (TILs) and regulatory T cells (Tregs) in rectal cancer patients receiving neoadjuvant chemoradiotherapy. Materials and methods: This is a single-center, prospective study. Forty patients diagnosed with middle and lower rectal tumors were enrolled in the study between March 2018 and December 2019. Nutrition protocols were given to all study subjects prior …

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Blood Neurofilament Light Chain And Thrombospondin-1 Levels Of Patients With Autism Spectrum Disorder, Cem Paketçi̇, Çağatay Ermi̇ş, Ali̇riza Şi̇şman, Semra Hiz, Burak Baykara, Uluç Yi̇ş Jan 2022

Blood Neurofilament Light Chain And Thrombospondin-1 Levels Of Patients With Autism Spectrum Disorder, Cem Paketçi̇, Çağatay Ermi̇ş, Ali̇riza Şi̇şman, Semra Hiz, Burak Baykara, Uluç Yi̇ş

Turkish Journal of Medical Sciences

Background/aim: Neurofilaments are intermediary filaments associated with neurodegenerative processes. Thrombospondin-1 (TSP1) is a biological marker playing a role in synaptogenesis. This study aimed to investigate serum neurofilament light chain (NFL), and TSP1 levels of patients with autism spectrum disorder (ASD) compared to typically developing (TD) children. Materials and methods: Forty-three patients with ASD and forty-five TD children were included. Serum biomarker levels were measured using the sandwich ELISA technique. The Childhood Autism Rating Scale (CARS) was implemented to measure the severity of ASD. Results: NFL and TSP1 levels did not differ between study groups (For NFL, ASD = 47.8 ± …

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Predictors Of Lymphovascular Invasion In Estrogen Receptor Positive/Her-2 Negative Breast Cancer Patients Treated With Neoadjuvant Chemotherapy, Eyyüp Çavdar, Yakup İri̇ağaç Jan 2022

Predictors Of Lymphovascular Invasion In Estrogen Receptor Positive/Her-2 Negative Breast Cancer Patients Treated With Neoadjuvant Chemotherapy, Eyyüp Çavdar, Yakup İri̇ağaç

Turkish Journal of Medical Sciences

Background/aim: Lymphovascular invasion (LVI) is considered a high-risk factor for recurrence in early-stage breast cancer, hence examination of LVI in pathological samples is an absolute recommendation. We aim to investigate predictive factors of LVI in preneoadjuvant chemotherapy (NAC) patients with estrogen receptor positive (ER+) and human epidermal growth factor receptor 2 negative (HER2-) molecular subtypes of breast cancer. Materials and methods: One hundred and thirty-four patients treated with NAC were included in this study who were ER+/HER2-. The clinical characteristics of the patients, the data obtained from the core needle biopsy before NAC and the LVI status in the pathology …

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Morbid Obesity Leads To Increased Skin Autofluorescence Independent Of Metabolic Syndrome Components, Tuğçe Apaydin, Di̇lek Yavuz Jan 2022

Morbid Obesity Leads To Increased Skin Autofluorescence Independent Of Metabolic Syndrome Components, Tuğçe Apaydin, Di̇lek Yavuz

Turkish Journal of Medical Sciences

Background/aim: Obesity, diabetes mellitus, and metabolic syndrome (MetS) are associated with increased accumulated skin advanced glycation end products. We aimed to evaluate the association of MetS components with skin autofluorescence (SAF) in patients with morbid obesity. Material and methods: Eight hundred and one patients with morbid obesity and 94 age-matched controls with normal body mass index (BMI) and normal glucose metabolism were included. Advanced glycation end products (AGEs) were measured using SAF in the forearm, with an AGE reader. Results: The prevalence of MetS in patients with morbid obesity was 65.5% (n = 525). Type 2 diabetes mellitus (type 2 …

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