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Articles 72601 - 72630 of 76387
Full-Text Articles in Entire DC Network
Conceptualising Early Career Teachers’ Agency And Accounts Of Social Action In Disadvantaged Schools, Margaret Kettle, Bruce Burnett, Jo Lampert, Barbara Comber, Naomi Barnes
Conceptualising Early Career Teachers’ Agency And Accounts Of Social Action In Disadvantaged Schools, Margaret Kettle, Bruce Burnett, Jo Lampert, Barbara Comber, Naomi Barnes
Australian Journal of Teacher Education
This article examines the accounts of actions undertaken by Early Career Teachers (ECTs) recently graduated from a social justice-oriented Initial Teacher Education (ITE) program and employed in complex school settings with high levels of student diversity, disadvantage, and poverty. The study drew on theories of teacher agency and agency more broadly to examine the workshadowing observations of the teachers’ practice in classrooms augmented by their reflective accounts in interviews. The study found that the ECTs’ agency, or contextualised social action, can be conceptualised as temporally embedded social engagement directed at addressing their students’ cultural, social and academic needs. The teachers …
Gender Differences And Motivation For The Teaching Profession: Why Do Men Choose (Not) To Teach?, Ivana Pikić Jugović, Ana Maskalan, Tea Pavin Ivanec
Gender Differences And Motivation For The Teaching Profession: Why Do Men Choose (Not) To Teach?, Ivana Pikić Jugović, Ana Maskalan, Tea Pavin Ivanec
Australian Journal of Teacher Education
The aim of this study was to explore gender differences in motivation for choosing teaching as a profession and perceptions of men’s demotivation for the choice of this profession. 279 preservice subject teachers from the University of Zagreb, Croatia, filled in the FIT-Choice Scale (Watt & Richardson, 2007) and the Demotivation of Men for Teaching Career Choice Scale. Results revealed that, regardless of their gender, preservice subject teachers were primarily motivated by the intrinsic and social utility values of teaching, while specific gender differences imply the importance of the role of social factors in men’s choice of this career. Low …
Gender And Stress Levels Among Pre-Service Teachers, Gretchen Geng, Leigh Disney, Richard Midford, Jenny Buckworth
Gender And Stress Levels Among Pre-Service Teachers, Gretchen Geng, Leigh Disney, Richard Midford, Jenny Buckworth
Australian Journal of Teacher Education
This study used gender-sensitive research to investigate stress levels and stressors among pre-service teachers. The differences and similarities in stress levels between male and female pre-service teachers were studied. There were five significant findings: 1) both male and female pre-service teachers had high-stress levels; 2) male pre-service teachers had higher stress levels than females; 3) male pre-service teachers' stress has a strong relationship with their ages, while it was not for female pre-service teachers; 4) male pre-service teachers preferred to undertake their placement and commence their teaching career in middle or higher year level sectors, while female students preferred to …
Perceived Value Of Work-Integrated Learning On The Teaching Efficacy And Classroom Management Of Pre-Service Teachers., Casey P. Mainsbridge, Vaughan Cruickshank, Kira Patterson, Arto Gråstén
Perceived Value Of Work-Integrated Learning On The Teaching Efficacy And Classroom Management Of Pre-Service Teachers., Casey P. Mainsbridge, Vaughan Cruickshank, Kira Patterson, Arto Gråstén
Australian Journal of Teacher Education
The aim of this study was to examine associations of teaching competence, autonomous motivation, and self-efficacy between two groups of pre-service teachers enrolled in a four-year Bachelor of Education degree program. One group participated in a Work-Integrated Learning (WIL) pathway and one who did not participate in a Work-Integrated Learning pathway. Self-reports of basic psychological needs, motivational regulations, and self-efficacy were completed by 116 pre-service teachers. Findings indicated that pre-service teachers who participated in the WIL pathway had higher levels of efficacy in classroom management, and pre-service teachers who participated in the WIL pathway had higher perceptions of identified regulation, …
Prevalence And Associated Risk Factors Of African Animal Trypanosomiasis In Cattle In Lambwe, Kenya, Ivy Sylvia Okello, Eliakunda Mafie, Gillian Eastwood, Jahashi Nzalawahe, Leonard E.G Mboera, Samuel Onyoyo
Prevalence And Associated Risk Factors Of African Animal Trypanosomiasis In Cattle In Lambwe, Kenya, Ivy Sylvia Okello, Eliakunda Mafie, Gillian Eastwood, Jahashi Nzalawahe, Leonard E.G Mboera, Samuel Onyoyo
All Rsif Scholars' Publications
Background. African animal trypanosomiasis (AAT) affects livestock productivity in sub-Saharan Africa. This study aimed to determine cattle AAT’s prevalence and associated risk factors in Lambwe Valley, Kenya. Methods. In a cross-sectional survey, livestock owners were recruited from four villages of Lambwe in Homa Bay, Kenya. Blood samples were collected from the jugular veins of cattle, and buffy coat smears were examined under a microscope. Parasites were further detected using polymerase chain reaction (PCR). Using a semistructured questionnaire, livestock owners were interviewed on their knowledge of AAT and control practices. Chi-square and multilevel models were used for the analysis. Results. The …
Towards Resilient Agriculture To Hostile Climate Change In The Sahel Region: A Case Study Of Machine Learning-Based Weather Prediction In Senegal, Chimango Nyasulu, Awa Diattara, Assitan Traore Assitan Traore, Abdoulaye Deme, Cheikh Ba
Towards Resilient Agriculture To Hostile Climate Change In The Sahel Region: A Case Study Of Machine Learning-Based Weather Prediction In Senegal, Chimango Nyasulu, Awa Diattara, Assitan Traore Assitan Traore, Abdoulaye Deme, Cheikh Ba
All Rsif Scholars' Publications
To ensure continued food security and economic development in Africa, it is very important to address and adapt to climate change. Excessive dependence on rainfed agricultural production makes Africa more vulnerable to climate change effects. Weather information and services are essential for farmers to more effectively survive the increasing occurrence of extreme weather events due to climate change. Weather information is important for resource management in agricultural production and helps farmers plan their farming activities in advance. Machine Learning is one of the technologies used in agriculture for weather forecasting and crop disease detection among others. The objective of this …
Potential Uses Of Artisanal Gold Mine Tailings, With An Emphasis On The Role Of Centrifugal Separation Technique, Jeanne Pauline Munganyinka, Jean Baptiste Habinshuti, Jean Claude Ndayishimiye, Levie Mweene, Grace Ofori-Sarpong, Brajendra Mishra, Adelana R. Adetunji, Himanshu Tanvar
Potential Uses Of Artisanal Gold Mine Tailings, With An Emphasis On The Role Of Centrifugal Separation Technique, Jeanne Pauline Munganyinka, Jean Baptiste Habinshuti, Jean Claude Ndayishimiye, Levie Mweene, Grace Ofori-Sarpong, Brajendra Mishra, Adelana R. Adetunji, Himanshu Tanvar
All Rsif Scholars' Publications
Few investigations have focused on the potential uses of artisanal gold (Au) mine tailings, despite the fact that artisanal gold mining activity contributes to environmental issues such as greenhouse gas. Mineralogical characterizations of artisanal gold mine tailings in Miyove gold mine (Baradega and Masogwe) in Rwanda were investigated for potential utilization as a source of valuable gold, using the centrifugal separation technique. Results of X-ray diffraction analysis, energy dispersive X-ray spectroscopy, inductively coupled plasma mass spectrometry, inductively coupled plasma–optical emission spectroscopy, and X-ray fluorescence showed that artisanal gold mine tailings samples have significant amounts of gold to justify economical gold …
Can Gdp Be Predictive Of Fertility Rates In Sweden?, Hannah Coleman
Can Gdp Be Predictive Of Fertility Rates In Sweden?, Hannah Coleman
Honors Program: Senior Projects (Public)
Fertility rates in a country vary and can be influenced by numerous different aspects of an individual’s life and the society in which they live. One aspect that may influence fertility rates at the national level is the gross domestic product (GDP). GDP is an indicator of a country’s economic productivity. Because fertility is linked to both economic development and individual resources, GDP may be a useful indicator of fertility rates. If so, knowing or predicting GDP could be used to project the fertility rates of a population years into the future. To determine if a reasonable connection between GDP …
Transplant Surgery: Kidney And Pancreas, Lvpg Transplant Surgery
Transplant Surgery: Kidney And Pancreas, Lvpg Transplant Surgery
Department of Surgery
No abstract provided.
Effects Of Hearing Aid Amplification On The Ability Of Individuals With Hearing Loss To Perceive Spectral Information, Angela Huebert, Marc Brennan
Effects Of Hearing Aid Amplification On The Ability Of Individuals With Hearing Loss To Perceive Spectral Information, Angela Huebert, Marc Brennan
Honors Program: Senior Projects (Public)
Individuals with sensorineural hearing loss often struggle to understand speech even with the use of hearing aids; simply making sounds louder is not enough. Listeners decode various speech sounds with the help of spectral information, but how hearing aid amplification affects individuals’ ability to perceive those cues is not currently well understood. Altering the way hearing aids are programmed to provide amplification can potentially improve the ability of listeners with sensorineural hearing loss to access spectral information. The purpose of this study was to quantify the effects that hearing aid amplification has on the perception of spectral cues. Outcomes could …
Airport Noise As Public Bads: Comparative Remarks On Legal Challenges In Resolving The Neighbor Conflict Between The Airport And Landowners, Magdalena Habdas
Airport Noise As Public Bads: Comparative Remarks On Legal Challenges In Resolving The Neighbor Conflict Between The Airport And Landowners, Magdalena Habdas
Journal of Air Law and Commerce
Incompatible uses of land create neighbor conflicts connected with the notions of civil law immissions (non-trespassory invasions) or common law nuisance. These traditional instruments of resolving the neighbor conflict have their limitations when pollution (such as noise pollution produced by aviation) interferes with the use and enjoyment of land that affects numerous landowners. Lawmakers seek to resolve the neighbor conflict with public intervention in such circumstances. Instead of relying on the market, the state allocates entitlements, indicates how parties must behave, and prescribes the conditions under which lawmakers should conclude an agreement.
Interestingly, although the nuisance caused by airport noise …
Predicting Bearing Fault In The Drone Freight Industry: Legal Liability In Australia, Prue Vines, Anthony Song, Matthew Priestley, Elias Aboutanios
Predicting Bearing Fault In The Drone Freight Industry: Legal Liability In Australia, Prue Vines, Anthony Song, Matthew Priestley, Elias Aboutanios
Journal of Air Law and Commerce
Many people are now aware of drones or remotely piloted aircraft (RPAs), and several others have predicted the significant impacts that drones will bring across society. Today, there is an expectation that drones will play a pivotal role in industries such as surveillance, security, surveying, construction, and freight transport. However, in all these cases, whenever a drone is flying over a populated area, it poses a danger to people or things on the ground. Perhaps the sector where the greatest risk of injury to the everyday person exists is the drone delivery industry. The drone freight industry is proliferating fast, …
Private Law Aspects Of Suborbital Flights: Second- And Third-Party Liability And Insurance, Tanja Masson-Zwaan
Private Law Aspects Of Suborbital Flights: Second- And Third-Party Liability And Insurance, Tanja Masson-Zwaan
Journal of Air Law and Commerce
Two companies carried private citizens to the edge of space in July 2021. Although suborbital flights have so far taken place within one jurisdiction—they start and end in the same state, do not pass through foreign airspace, or meet both criteria—they will become international when transportation between two points in different states via outer space becomes a reality. International law is ambiguous about the regulation of suborbital flights; neither international air law nor international space law explicitly apply. It is also unclear which organization or institution should be mandated with the international regulation of suborbital flights. The legal uncertainties must …
Pulsed Nuclear Space Propulsion And International Law: Some Preliminary, Glenn Reynolds, Leigh Outten
Pulsed Nuclear Space Propulsion And International Law: Some Preliminary, Glenn Reynolds, Leigh Outten
Journal of Air Law and Commerce
Pulsed Nuclear Space Propulsion, researched in the 1950s and 1960s by such eminent physicists as Freeman Dyson, Ted Taylor, Theodore von Karman, and Hans Bethe, involves propelling large spacecraft using compact nuclear explosions from specialized atomic devices. This technology is often known by the name of the Air Force project in which it was developed: Orion. It has long been believed that the 1962 Limited Test Ban Treaty prohibits the use of nuclear pulse space propulsion. After a survey of the Orion project and its results and a review of the applicable law, this Article concludes that language in the …
Vertiports: Ready For Take-Off … And Landing, Benjamyn Scott
Vertiports: Ready For Take-Off … And Landing, Benjamyn Scott
Journal of Air Law and Commerce
While aviation has been used in transportation for decades, the use of vertical takeoff and landing (VTOL) aircraft for large-scale, low-cost, green, sustainable, and integrated mobility in populated areas is a new phenomenon. Despite the importance of ground infrastructure for embarkation and disembarkation of passengers, cargo, and mail, questions remain on how these “vertiports” are or should be regulated and how they will relate to existing regulated ground infrastructure such as aerodromes, airports, and heliports. Therefore, several questions arise: what is a vertiport; how do vertiports relate to other aviation infrastructure; what are the legal implications of having different terms; …
Cabotage And Deregulatory Anomalies, Timothy M. Ravich
Cabotage And Deregulatory Anomalies, Timothy M. Ravich
Journal of Air Law and Commerce
The strangest airline route in America is between Pago Pago and the Manu’a Islands in American Samoa. No U.S. carrier serves this “domestic” route. Therefore, it is the only route between two points in the United States (or, more accurately, its territories) that is regularly scheduled service by a non-U.S.-flagged airline. The Pago Pago–Manu’a Islands flight is thus an unprecedented and unique exception to a federal law that permits only U.S. carriers operating U.S.-registered aircraft to fly between U.S. states and territories. Under existing U.S. cabotage policies, moreover, states and U.S. territories are divested of all power to manage …
Corporate Resiliency And Relevancy In The Private Ordering Era, Megan Wischmeier Shaner
Corporate Resiliency And Relevancy In The Private Ordering Era, Megan Wischmeier Shaner
Faculty Articles
Firm-specific private ordering has flourished in the twenty-first century. Public companies are seeing more and more governance contracting in traditional venues such as the bylaws and charter, as well as in less conventional places like shareholder agreements and dual-class-like contracts. Decisions legitimizing private ordering in the corporate setting contain strong contractarian language and rely heavily on contract – and not corporate – principles to justify their holdings. In addition, recent statutory amendments have chipped away at traditionally mandatory features of the corporation, thereby reinforcing the contractual view of the corporate form and fueling the private ordering movement. All told, the …
Inequality By Unnatural Selection: The Impact Of Tax Code Bias On The Racial Wealth Gap, Phyllis C. Taite
Inequality By Unnatural Selection: The Impact Of Tax Code Bias On The Racial Wealth Gap, Phyllis C. Taite
Faculty Articles
No abstract provided.
Using Incremental Ensemble Learning Techniques To Design Portable Intrusion Detection For Computationally Constraint Systems, Promise Ricardo Agbedanu, James Rwigema, Richard Musabe, Ignace Gatare
Using Incremental Ensemble Learning Techniques To Design Portable Intrusion Detection For Computationally Constraint Systems, Promise Ricardo Agbedanu, James Rwigema, Richard Musabe, Ignace Gatare
All Rsif Scholars' Publications
Computers have evolved over the years, and as the evolution continues, we have been ushered into an era where high-speed internet has made it possible for devices in our homes, hospital, energy, and industry to communicate with each other. This era is known as the Internet of Things (IoT). IoT has several benefits in a country’s economy’s health, energy, transportation, and agriculture sectors. These enormous benefits, coupled with the computational constraint of IoT devices, make it challenging to deploy enhanced security protocols on them, making IoT devices a target of cyber-attacks. One approach that has been used in traditional computing …
A Comprehensive Review On The Decontamination Of Lead(Ii) From Water And Wastewater By Low-Cost Biosorbents, Jonas Bayuo, Mwemezi Rwiza, Kelvin Mtei
A Comprehensive Review On The Decontamination Of Lead(Ii) From Water And Wastewater By Low-Cost Biosorbents, Jonas Bayuo, Mwemezi Rwiza, Kelvin Mtei
All Rsif Scholars' Publications
The disadvantages of conventional methods in water and wastewater management including the demand for high energy consumption, the creation of secondary toxic sludge, and operation cost are much too high for developing countries. However, adsorption using low-cost biosorbents is the most efficient non-conventional technique for heavy metals removal. The high adsorption capacities, cost-effectiveness, and the abundance of agricultural waste materials in nature are the important parameters that explain why these biosorbents are economical for heavy metals removal. The present investigation sought to review the biosorption of lead [Pb(II)] onto low-cost biosorbents to understand their adsorption mechanism. The review shows that …
Remediation Of Soils Contaminated By Fluoride Using A Fermentation Product Of Seaweed (Eucheuma Cottonii), Ruth Lorivi Moirana, Josephine Mkunda, Marcos Paradelo, Revocatus Machunda, Kelvin Mtei
Remediation Of Soils Contaminated By Fluoride Using A Fermentation Product Of Seaweed (Eucheuma Cottonii), Ruth Lorivi Moirana, Josephine Mkunda, Marcos Paradelo, Revocatus Machunda, Kelvin Mtei
All Rsif Scholars' Publications
This study investigated the efficacy of fermented seaweed (Eucheuma cottonii) on the remediation of fluoride-contaminated soil. The soil was amended with either 1.25, 3.0, or 5.0% (w/w) fermented seaweed (FSW), parallel with the controls (0%). The amendment improved the physicochemical properties of the soil particularly pH regulated from strong alkaline (9.3) to neutral (7.0) which is essential for germination, crop growth, and yield. The amount of water soluble-fluoride (Ws-F) dropped from 81.7 ± 3.1 mg/kg to 42.7 ± 2.4, 33.7 ± 1.2, 19.6 ± 0.9, and 12 ± 1.3 mg/kg following 0, 1.25, 3, and 5% amendment dosage, re- spectively. …
Capacitive Deionization: A Promising Technology For Water Defluoridation: A Review, Tusekile Alfredy, Joyce Elisadiki, Yusufu Abeid Chande Jande
Capacitive Deionization: A Promising Technology For Water Defluoridation: A Review, Tusekile Alfredy, Joyce Elisadiki, Yusufu Abeid Chande Jande
All Rsif Scholars' Publications
Capacitive deionization (CDI) is among the promising technologies employed for water purification. CDI has been studied for the removal of various ionic species from water including fluoride ion (F−) with promising results. However, there is no comprehensive literature that summarizes the use of CDI for water defluoridation applications. Therefore, this review paper critically analyzes different electrode materials that have been studied for water defluoridation, their electrosorption capacities and F− removal efficiencies. It further discussed the parameters that influence CDI efficiency during defluoridation and point out the issues of F− selectivity when co-existing with other ions in …
African Animal Trypanosomiasis: A Systematic Review On Prevalence, Risk Factors And Drug Resistance In Sub-Saharan Africa, Ivy Sylvia Okello, Eliakunda Mafie, Jahashi Nzalawahe, Leonard E.G Mboera
African Animal Trypanosomiasis: A Systematic Review On Prevalence, Risk Factors And Drug Resistance In Sub-Saharan Africa, Ivy Sylvia Okello, Eliakunda Mafie, Jahashi Nzalawahe, Leonard E.G Mboera
All Rsif Scholars' Publications
African animal trypanosomiasis (AAT) a parasitic disease of livestock in sub-Saharan Africa causing tremendous loses. Sub-Saharan continental estimation of mean prevalence in both large and small domestic animals, risk factors, tsetse and non-tsetse prevalence and drug resistance is lacking. A review and meta-analysis was done to better comprehend changes in AAT prevalence and drug resistance. Publish/Perish software was used to search and extract peer-reviewed articles in Google scholar, PubMed and CrossRef. In addition, ResearchGate and African Journals Online (AJOL) were used. Screening and selection of articles from 2000–2021 was performed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses …
Drivers Of Post-Harvest Aflatoxin Contamination: Evidence Gathered From Knowledge Disparities And Field Surveys Of Maize Farmers In The Rift Valley Region Of Kenya, Grace Wanjiku Gachara, Rashid Suleiman, Sara El Kadili, Essaid Ait Barka, Beatrice Kilima, Rachid Lahlali Rachid Lahlali
Drivers Of Post-Harvest Aflatoxin Contamination: Evidence Gathered From Knowledge Disparities And Field Surveys Of Maize Farmers In The Rift Valley Region Of Kenya, Grace Wanjiku Gachara, Rashid Suleiman, Sara El Kadili, Essaid Ait Barka, Beatrice Kilima, Rachid Lahlali Rachid Lahlali
All Rsif Scholars' Publications
Maize-dependent populations in sub-Saharan Africa are continually exposed to aflatoxinpoisoning owing to their regular consumption of this dietetic cereal. Being a staple in Kenyanhouseholds, consumption of maize-based meals is done almost daily, thereby exposing consumers toaflatoxicoses. This study assessed awareness levels, knowledge disparities, and perceptions regardingaflatoxin contamination at the post-harvest phase among farmers in the Rift Valley Region of Kenya.Households were randomly selected using a geographical positioning system (GPS) overlay of theagro-ecological zones within Uasin Gishu and Elgeyo Marakwet counties. Face-to-face interviewswere conducted in 212 smallholder and large-scale farms. The study documented the demographicprofiles of farmers and knowledge, awareness, and …
Glioma And The Gut-Brain Axis: Opportunities And Future Perspectives, Antonio Dono, Jack Nickles, Ana G Rodriguez-Armendariz, Braden C Mcfarland, Nadim J Ajami, Leomar Y Ballester, Jennifer A Wargo, Yoshua Esquenazi
Glioma And The Gut-Brain Axis: Opportunities And Future Perspectives, Antonio Dono, Jack Nickles, Ana G Rodriguez-Armendariz, Braden C Mcfarland, Nadim J Ajami, Leomar Y Ballester, Jennifer A Wargo, Yoshua Esquenazi
Faculty, Staff and Student Publications
The gut-brain axis has presented a valuable new dynamic in the treatment of cancer and central nervous system (CNS) diseases. However, little is known about the potential role of this axis in neuro-oncology. The goal of this review is to highlight potential implications of the gut-brain axis in neuro-oncology, in particular gliomas, and future areas of research. The gut-brain axis is a well-established biochemical signaling axis that has been associated with various CNS diseases. In neuro-oncology, recent studies have described gut microbiome differences in tumor-bearing mice and glioma patients compared to controls. These differences in the composition of the microbiome …
A Novel Group Of Genes That Cause Endocrine Resistance In Breast Cancer Identified By Dynamic Gene Expression Analysis, Arvand Asghari, Katherine Wall, Michael Gill, Natascha Del Vecchio, Farnaz Allahbakhsh, Jacky Wu, Nan Deng, W Jim Zheng, Hulin Wu, Michihisa Umetani, Vahed Maroufy
A Novel Group Of Genes That Cause Endocrine Resistance In Breast Cancer Identified By Dynamic Gene Expression Analysis, Arvand Asghari, Katherine Wall, Michael Gill, Natascha Del Vecchio, Farnaz Allahbakhsh, Jacky Wu, Nan Deng, W Jim Zheng, Hulin Wu, Michihisa Umetani, Vahed Maroufy
Faculty, Staff and Student Publications
Breast cancer (BC) is the most common type of cancer diagnosed in women. Among female cancer deaths, BC is the second leading cause of death worldwide. For estrogen receptor-positive (ER-positive) breast cancers, endocrine therapy is an effective therapeutic approach. However, in many cases, an ER-positive tumor becomes unresponsive to endocrine therapy, and tumor regrowth occurs after treatment. While some genetic mutations contribute to resistance in some patients, the underlying causes of resistance to endocrine therapy are mostly undetermined. In this study, we utilized a recently developed statistical approach to investigate the dynamic behavior of gene expression during the development of …
Effects Of Tamoxifen Inducible Mercremer On Gene Expression In Cardiac Myocytes In Mice, Leila Rouhi, Siyang Fan, Sirisha M Cheedipudi, Melis Olcum, Hyun-Hwan Jeong, Zhongming Zhao, Priyatansh Gurha, Ali J Marian
Effects Of Tamoxifen Inducible Mercremer On Gene Expression In Cardiac Myocytes In Mice, Leila Rouhi, Siyang Fan, Sirisha M Cheedipudi, Melis Olcum, Hyun-Hwan Jeong, Zhongming Zhao, Priyatansh Gurha, Ali J Marian
Faculty, Staff and Student Publications
The Cre-LoxP technology, including the tamoxifen (TAM) inducible MerCreMer (MCM), is increasingly used to delineate gene function, understand the disease mechanisms, and test therapeutic interventions. We set to determine the effects of TAM-MCM on cardiac myocyte transcriptome. Expression of the MCM was induced specifically in cardiac myocytes upon injection of TAM to myosin heavy chain 6-MCM (Myh6-Mcm) mice for 5 consecutive days. Cardiac function, myocardial histology, and gene expression (RNA-sequencing) were analyzed 2 weeks after TAM injection. A total of 346 protein coding genes (168 up- and 178 down-regulated) were differentially expressed. Transcript levels of 85 genes, analyzed …
An Ensemble-Based Deep Convolutional Neural Network For Computer-Aided Polyps Identification From Colonoscopy, Pallabi Sharma, Bunil Kumar Balabantaray, Kangkana Bora, Saurav Mallik, Kunio Kasugai, Zhongming Zhao
An Ensemble-Based Deep Convolutional Neural Network For Computer-Aided Polyps Identification From Colonoscopy, Pallabi Sharma, Bunil Kumar Balabantaray, Kangkana Bora, Saurav Mallik, Kunio Kasugai, Zhongming Zhao
Faculty, Staff and Student Publications
Colorectal cancer (CRC) is the third leading cause of cancer death globally. Early detection and removal of precancerous polyps can significantly reduce the chance of CRC patient death. Currently, the polyp detection rate mainly depends on the skill and expertise of gastroenterologists. Over time, unidentified polyps can develop into cancer. Machine learning has recently emerged as a powerful method in assisting clinical diagnosis. Several classification models have been proposed to identify polyps, but their performance has not been comparable to an expert endoscopist yet. Here, we propose a multiple classifier consultation strategy to create an effective and powerful classifier for …
A Deep Learning-Based Framework For Supporting Clinical Diagnosis Of Glioblastoma Subtypes, Sana Munquad, Tapas Si, Saurav Mallik, Asim Bikas Das, Zhongming Zhao
A Deep Learning-Based Framework For Supporting Clinical Diagnosis Of Glioblastoma Subtypes, Sana Munquad, Tapas Si, Saurav Mallik, Asim Bikas Das, Zhongming Zhao
Faculty, Staff and Student Publications
Understanding molecular features that facilitate aggressive phenotypes in glioblastoma multiforme (GBM) remains a major clinical challenge. Accurate diagnosis of GBM subtypes, namely classical, proneural, and mesenchymal, and identification of specific molecular features are crucial for clinicians for systematic treatment. We develop a biologically interpretable and highly efficient deep learning framework based on a convolutional neural network for subtype identification. The classifiers were generated from high-throughput data of different molecular levels, i.e., transcriptome and methylome. Furthermore, an integrated subsystem of transcriptome and methylome data was also used to build the biologically relevant model. Our results show that deep learning model outperforms …
Crucial Roles Of Microrna-16-5p And Microrna-27b-3p In Ameloblast Differentiation Through Regulation Of Genes Associated With Amelogenesis Imperfecta, Akiko Suzuki, Hiroki Yoshioka, Teng Liu, Aania Gull, Naina Singh, Thanh Le, Zhongming Zhao, Junichi Iwata
Crucial Roles Of Microrna-16-5p And Microrna-27b-3p In Ameloblast Differentiation Through Regulation Of Genes Associated With Amelogenesis Imperfecta, Akiko Suzuki, Hiroki Yoshioka, Teng Liu, Aania Gull, Naina Singh, Thanh Le, Zhongming Zhao, Junichi Iwata
Faculty, Staff and Student Publications
Amelogenesis imperfecta is a congenital disorder within a heterogeneous group of conditions characterized by enamel hypoplasia. Patients suffer from early tooth loss, social embarrassment, eating difficulties, and pain due to an abnormally thin, soft, fragile, and discolored enamel with poor aesthetics and functionality. The etiology of amelogenesis imperfecta is complicated by genetic interactions. To identify mouse amelogenesis imperfecta-related genes (mAIGenes) and their respective phenotypes, we conducted a systematic literature review and database search and found and curated 70 mAIGenes across all of the databases. Our pathway enrichment analysis indicated that these genes were enriched in tooth development-associated pathways, forming four …