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“There Was Me Before Prp, And Then There Was Me After I Participated In Prp”: A Mixed-Methods Program Evaluation Of A Pharmacy Summer Pipeline Program, Cynthia Schaefer

Graduate Research Theses & Dissertations

Nationwide, there has been a decline in the number of applicants to PharmD programs.

Additionally, there is a lack of diversity in the healthcare workforce that leads to inequitable healthcare for diverse populations of patients. As a result, various recruitment tactics, including pipeline programs, have been used to develop a larger, more diverse applicant pool to the College of Pharmacy at a regional satellite campus in the Midwest. The purpose of this mixed methods summative program evaluation was to examine the experiences of participants of a pipeline program hosted at a regional satellite campus for a pharmacy program to determine …

Modeling The Broader Impact Of Science And Health Using Social Media, Abdul Rahman Shaikh

Graduate Research Theses & Dissertations

Research and development have always initiated innovation and breakthroughs in technology. These technological advancements in recent years have provided a global medium for research to be disseminated through online platforms. These web-based platforms and the interactions that take place on them affect the dissemination, impact, and perception of online information. This thesis investigates the broader impact of science and health using social media posts, online patents, videos, and images by building machine learning and topic models. First, this study predicts patent citations to scientific research and identifies important factors essential to economic impact. We found that the citation of research …

The Impact Of Covid-19 On Gendered Parental And Household Work Inequality: A Qualitative Study On The Lived Experiences Of Women As Educators And Mothers During The Covid-19 Pandemic, Carly Stumphy

Graduate Research Theses & Dissertations

The current study examines how female teachers manage their roles as educators and parents during the COVID-19 pandemic using Erving Goffman’s theory on Role Management. Additionally, the research looks into the impact of gender inequality in housework and childcare. In total, ten women were interviewed using a semi-structured approach, and the data was then analyzed using a modified grounded methodology. The analysis revealed that the pandemic increased domestic work and made it difficult for these women to balance their roles. It was found that effective communication and the development of boundaries were crucial in maintaining the performance of roles. However, …

African American Males Of Men Of Vision: A Case Study Of Self-Efficacy, A Sense Of Belonging, And Their Perception Of Community College, Jorge Theotis Tennin

Graduate Research Theses & Dissertations

This qualitative case study explored self-efficacy and sense of belonging among African American males who participated in Men of Vision and their perception of community college. Ten students of the community college participated in the study through individual, in-depth interviews with the participants addressing three primary research questions: 1) How did being a member of an organization change your perception of higher education, specifically community colleges? 2) How did Men of Vision help you gain a sense of belonging on a college campus? 3) What did you learn about yourself while being a member of Men of Vision? The focus …

Study Protocol To Analyze The Effects Of Posture And Exoskeleton On Human Exposure To Hand-Transmitted Vibration, Parisa Torkinejad Ziarati

Graduate Research Theses & Dissertations

Exposure to power hand tool-generated vibrations may lead to several health disorders collectively known as hand-arm vibration (HAV) syndromes. Power hand tools are often used in overhead postures in the manufacturing and construction industries. However, HAV risks are examined in the front-of-body posture in the existing safety standards and guidelines. Therefore, it is important to understand the effects of overhead working posture on vibration transmissibility (VT) in the upper extremities (UEs) and the spine. Secondly, there is a rising trend of using occupational exoskeletons (Exos) in the manufacturing and construction industries, especially involving overhead work with power hand tools. However, …

Cambodian Government’S Responses To The Covid-19 Pandemic: A Success Story, Sopheachanboramey Tuon

Graduate Research Theses & Dissertations

This thesis addresses why the Cambodian government could handle the challenges of the COVID-19 pandemic. It investigates the factors that contribute to the government’s success. I argue that Cambodia’s success in tackling the COVID-19 crisis depends on the state’s possession of infrastructural power, which effectively enabled the government to mobilize resources, surveil people, disseminate information, and roll out vaccination across the country. Furthermore, I argue that Cambodia’s success in handling the COVID-19 pandemic also links to the government’s longing to enhance its legitimacy. These arguments are supported by the empirical findings from the interview of 25 respondents and the review …

Succinylated Polyethylenimine Gene Delivery Agents For Enhanced Transfection Efficacy, Md. Nasir Uddin

Theses and Dissertations--Chemistry

Gene therapy aims to treat patients by altering or controlling gene expression. Today, most clinical approaches are viral-based due to their inherent gene delivery activity. However, there is still a significant interest in nonviral alternatives for gene delivery, particularly synthetic lipids and polymers, that do not suffer the immunogenicity, high cost, or mutagenesis concerns of viral vectors. Polymeric vectors are of particular interest due to the ability to further tune the polymer properties through the incorporation of additional functional units such as targeting ligands or shielding domains. Polyethylenimine (PEI), a highly cationic polymer, is often considered a benchmark for polymer-based …

Developments In Gold(Iii) Scaffolds For Protein Bioconjugation And Enhanced Anticancer Activity, Sailajah Gukathasan

Theses and Dissertations--Chemistry

Site-selective modifications of target proteins using specially designed small molecules is a powerful tool that has been extensively utilized in biomedicine. Small molecules can modify proteins either covalently or non-covalently depending on their structures and intrinsic chemical reactivity. Covalent chemical modification presents a more stable and often irreversible interaction with target proteins; unlike non-covalent binders, which form weak, reversible interactions with protein. Therefore, covalent modifiers represent an effective class of therapeutics due to their stability and irreversibility once bound to target proteins of interest. I hypothesized that tuning biocompatible, high-valent gold(III) complexes toward nucleophile-induced reductive elimination will lead to covalent …

The Design And Synthesis Of New Organic Dithiols For Environmental Applications, Shashika Nadishani Bandara

Theses and Dissertations--Chemistry

A thiol molecule, 2,6-pyridinediamidoethanethiol (PB9), was synthesized based on the pyridine-2,6-dicarboxamide scaffold with appended cysteamine groups. PB9 acts as an effective chelator for Pb(II) due to multiple binding sites (N₃S₂) through irreversible binding precipitating Pb(II). Removal of aqueous Pb(II) from solution was demonstrated by exploring the effects of time, initial PB9:Pb(II) ratios, pH, exposure time, and solution temperature. After 15 min the Pb(II) concentrations were reduced from 50.00 ppm to 0.30 ppm (99.4%) and 0.25 ppm (99.5%) for PB9:Pb ratios of 1:1 and 2:1, respectively. Removal of > 93% Pb(II) was observed over multiple pH values with …

1,2-Diamination Of Alkenes Via Reduction Of 1,2,3-Triazolinium Ions, Setareh Saryazdi

Theses and Dissertations--Chemistry

1,2-Diamine substructures are prevalent functional motifs in natural products, pharmaceutical compounds, and ligands. The interesting functionalities of 1,2-diamines have inspired many synthetic chemists to design various methodologies for preparing these structures from simple precursors such as alkenes. In this work, we described two different but related methods using simple and easily accessible reagents for 1,2-diamination of alkenes. In the first method, an alkene undergoes 1,3-dipolar cycloaddition with an organic azide to form a 1,2,3-triazoline. Subsequent N-alkylation of the generated 1,2,3-triazoline gives the 1,2,3-triazolinium ion, which is then hydrogenated over Raney Ni with a balloon of H₂ to produce …

Phomopsis Stem Canker Of Sunflower (Helianthus Annuus L.): Etiology And Epidemiological Conditions Affecting Endophytic Population Of Diaporthe Spp., And Fungicide Efficacy, Nabin Kumar Dangal

Electronic Theses and Dissertations

Phomopsis stem canker (PSC), caused by species of Diaporthe, is a major disease of sunflower (Helianthus annuus L.) in the U.S., which can cause yield loss over 40%. The disease prevalence increased since 2010 in the major sunflower producing U.S. states of Nebraska, Minnesota, North Dakota, and South Dakota. Previous studies on the use of foliar fungicides in managing Phomopsis stem canker indicated mixed results on their efficacy in disease reduction and yield gain. Additionally, we do not have sufficient information on asymptomatic colonization by endophytic Diaporthe on sunflower tissue and how foliar fungicide and weather parameters affect the prevalence …

Study Of Root System Architectural Traits Of Oat And Response To Endophyte Inoculation And Drought Stress, Krishna Ghimire

Electronic Theses and Dissertations

Oat is an important cereal crop grown worldwide. Oats have the potential to contribute to human health due to their unique nutritional attributes. Developing oat cultivars with efficient root systems able to extract heterogeneously distributed soil resources can help maintain yield under drought conditions and in nutrient poor soil. Various root traits determine the soil volume that is explored by the root system for resource acquisition. Knowledge about the genetic control of oat root traits and response to biotic and abiotic environmental factors is lacking. Identifying quantitative trait loci associated with root traits and understanding the response of roots to …

Determining The Impact Of Corn Source On Nutrient Availability And Pig Performance, And Improving Boar Performance During Heat Stress, Jordan Jansen

Electronic Theses and Dissertations

The quality and effectiveness of the feedstuffs included in diets of production livestock directly impact yield efficiency and performance characteristics desired by producers. This thesis focuses on the performance and digestibility of corn from different countries in pig diets and how different feed additives can be supplemented to improve boar reproductive performance during heat stress. Corn is the largest energy source in common pig diets. The physical characteristics of corn such as broken kernels, foreign material, and excessive dust are said to negatively impact the quality of the grain for pig diets by being less digestible and a worsened nutrient …

The Bulletin: Sidney Kimmel Medical College At Thomas Jefferson University, Volume 71, Issue 1, Winter 2022

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

This issue includes:

• 5 - Dean's Column
• 6 - Time Capsule - The No Limits Klasko Era
• 14 - ICYMI (In Case You Missed It)
• 19 - A Message from Elizabeth A. Dale
• 20 - Discovery - University’s Global Reach Will Soon Extend into Space
• 21 - First Class of Med Students Completes JeffMD Curriculum
• 26 - Student Profile - Ryan Emoff
• 28 - Faculty Profile - Marc Altshuler, MD ‘01
• 30 - Reimagine
• 36 - Class Notes
• 38 - Alumni Weekend 2021
• 44 - Class Agent
• 46 - In Memoriam
• 48 - By the Numbers - SKMC Class of …

Nutritional Considerations For Transgender Patients, Mitchell Anderson, Emma Nye

Clinical Practice in Athletic Training

No abstract provided.

Anti-Grp-R Monoclonal Antibody Antitumor Therapy Against Neuroblastoma, Jingbo Qiao, Junquan Liu, Jillian C Jacobson, Rachael A Clark, Sora Lee, Li Liu, Zhiqiang An, Ningyan Zhang, Dai H Chung

Faculty, Staff and Student Publications

Standard treatment for patients with high-risk neuroblastoma remains multimodal therapy including chemoradiation, surgical resection, and autologous stem cell rescue. Immunotherapy has demonstrated success in treating many types of cancers; however, its use in pediatric solid tumors has been limited by low tumor mutation burdens. Gastrin-releasing peptide receptor (GRP-R) is overexpressed in numerous malignancies, including poorly-differentiated neuroblastoma. Monoclonal antibodies (mAbs) to GRP-R have yet to be developed but could serve as a potential novel immunotherapy. This preclinical study aims to evaluate the efficacy of a novel GRP-R mAb immunotherapy against neuroblastoma. We established four candidate anti-GRP-R mAbs by screening a single-chain …

Crossing The 'Color Bar': African American Soldiers In Britain And Australia During The Second World War, Joseph A. Dickinson

War, Diplomacy, and Society (MA) Theses

During the Second World War, African American soldiers were stationed all over the world as part of the American war effort. During these deployments, African Americans encountered a number of white societies, such as those in Britain and Australia, which they generally interacted with cordially. Good relations between African American soldiers and the local white populations angered many white servicemembers, who saw the lack of Jim Crow style segregation as a threat to the racial status quo, and attempted to enforce segregation overseas themselves. These attempts were often resisted fiercely by African American soldiers and the local white populations, both …

Review Of The Efficacy Of Methods In The Early Detection Of Vascular Dementia, Daniella G. Maciel, Charles J. Golden

Archives of Assessment Psychology

Various assessments are used to detect cognitive decline throughout the stages of vascular dementia (VaD); however, the literature lacks a review of assessment efficacy. Early signs of VaD may include a decline in executive functioning, processing speed, attention, visuospatial abilities, and memory retrieval deficits. This review examines peer-reviewed publications addressing the validity and efficacy of widely accepted (and some lesser-known) neuropsychological assessments used to detect cognitive dysfunction in VaD. in addition to some common related medical assessments. Articles reviewed here include selected case-control studies and a case. The Cambridge Cognitive Examination (CAMCOG) and the Montreal Cognitive Assessment (MoCA) surpassed the …

Inventory For The Assessment Of The Severity Of Body Integrity Dysphoria (The Bid Assessment), Maria A. Garbos, Erich Kasten

Archives of Assessment Psychology

Objective:Body integrity dysphoria (BID; also known as body integrity identity disorder, xenomelia, amputee identity disorder, or apotemnophilia) describes a very rare condition in which non-disabled people feel a desire or need for a physical disability (e.g., amputation, paralysis, or blindness). BID is included in the new version of ICD-11 (6C21: body integrity dysphoria), but, thus far, we are without a standard test of whether a subject suffers from BID and, if so, at what intensity. Accordingly, this study aimed to develop an inventory for the assessment of BID. Methods: We created a questionnaire comprising 80 items covering the desire for …

Preliminary Evidence Demonstrating The Utility Of The Wechsler Abbreviated Scale Of Intelligence–Second Edition (Wasi-Ii) In The Neurocognitive Assessment Of Alzheimer’S Disease, Samuel T. Gontkovsky, Joseph J. Ryan, David S. Kreiner, Gordon Teichner

Archives of Assessment Psychology

Although memory deterioration is the primary symptom of Alzheimer’s disease (AD), this may not be the first/only deficit of the disorder, necessitating more comprehensive assessment of neuropsychological functioning. This study examined the usefulness of the Wechsler Abbreviated Scale of Intelligence–Second Edition (WASI-II) in the neurocognitive assessment of AD. Participants were 68 individuals classified into AD, depression, and healthy comparison groups administered the WASI-II as part of an outpatient clinical neuropsychological evaluation. Patients with AD obtained significantly lower scores on the WASI-II relative to the standardization sample as well as healthy comparison and depressed participants. Classification accuracy statistics and receiver operating …

Front Pages

American Indian Law Review

No abstract provided.

Belated Justice: The Failures And Promise Of The Hawaiian Homes Commission Act, Troy J.H. Andrade

American Indian Law Review

No abstract provided.

Biography: Rennard Strickland

American Indian Law Review

No abstract provided.

Demographic, Clinical, And Co-Morbidity Characteristics Of Covid-19 Patients: A Retrospective Cohort From A Tertiary Hospital In Kenya, Reena Shah, Jasmit Shah, Nancy Kunyiha, Sayed Karar, Shahin Sayed, Salim Surani, Mansoor Saleh

Internal Medicine, East Africa

Introduction: The first documented case of COVID-19 in Kenya was recorded March of 2020. Co-morbidities including hypertension and diabetes have been associated with increased morbidity, hospitalization, and mortality among COVID-19 patients. This retrospective study describes the clinical characteristics, disease severity, and outcomes among the patient population at a tertiary hospital in Kenya.

Methods: This was a retrospective descriptive study of COVID-19 patients who were admitted between March 2020 and December 2020 at the Aga Khan University Hospital in Nairobi, Kenya. Data collected include patient demographic and baseline characteristics. Differences between patients who were known to have diabetes and hypertension during …

Languaging School Into Being : A Discourse Analysis Of Online Ela Classes Within The Context Of The Covid-19 Pandemic, Jason Christopher Toncic

Theses, Dissertations and Culminating Projects

At the beginning of the COVID-19 pandemic, school buildings across the United States shut their doors and transitioned students and teachers to remote learning, most often utilizing internet-based technology to provide either asynchronous or synchronous lessons. I was a high school English Language Arts teacher in Stone Valley School District in Northeastern New Jersey when the unprecedented school closures moved my classes online for the remainder of the 2019-2020 school year.

As a teacher researcher who specialized in New Literacy Studies, I was particularly sensitive to how students and I used technology to continue lessons after the school building shut …

Pre-Service Teachers And The Next Generation Of Agile Teaching Through Crisis, Makayla Carmichael, Maria L. Manning

Pedagogicon Conference Proceedings

Pre-service teacher candidates have experienced extreme stressors from COVID-19 through both the lens of postsecondary students and clinical practitioners. This duality provided a complex understanding of crisis management within instructional settings for future incoming teachers. This article discusses trauma-related student behavior brought on by COVID-19 and introduces agile teaching practices such as reflective practices and integrated use of technology. Reflective practices help educators unpack teaching practices and apply ideas and concepts in novel ways. Technology tools help to strengthen relationships, communication, and collaboration reducing crisis related behavior. Future implications include addressing technology inequity and crisis planning.

Tarsal Metric Trends Over The Medieval-Post-Medieval Transition In London, Malorie Albee

Journal Articles

The Medieval-Post-Medieval transition in England was an important shift in the human biocultural environment. With urbanization and industrialization came resultant changes in living and working conditions and subsequent effects on the skeleton. In addition, the Post-Medieval period ushered in changes in footwear and activity patterns, with potential consequences on foot bone morphology. The objective of this study is to compare calcaneal and talar lengths between the Medieval and Post-Medieval periods to determine whether there are quantifiable differences that correspond to shifting footwear and activity patterns. T-tests and ANCOVAs (and their non-parametric equivalents) were used to compare calcaneal and talar lengths …

Departments, Schools, Divisions, And Colleges: Organization Of Academic Units In Public Master’S Institutions In The United States, Brent Graves, Brian Cherry

Journal Articles

No abstract provided.

Church–State Entanglements In Southern Baptist Post-War Juvenile Delinquency Programs, Alan Willis

Journal Articles

No abstract provided.

The Roof Rat, Rattus Rattus, In Virginia, Ralph P. Eckerlin, Paige Berends, Cassidy Downing, Kurt E. Galbreath

Journal Articles

We collected a single specimen of Rattus rattus (Roof Rat) in Highland County, VA, a previously unknown locality for the species. We collected ecto- and endoparasites, including the louse Polyplax spinulosa, the tick Dermacentor variabilis (American Dog Tick), and the nematode Aspicularis americana. which we archived along with the host voucher specimen. Sequencing of the mitochondrial cytochrome b gene confirmed the rodent species identification based on comparisons to R. rattus sequences available in the GenBank database. Herein we review specimen records of Roof Rats and Rattus norvegicus (Brown Rat). Both species have a deep history in Virginia, but Roof Rats …