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2022

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Effects Of Increased Use Of Technology On Elementary School Students In The Classroom, Audri Lawrence Dec 2022

Effects Of Increased Use Of Technology On Elementary School Students In The Classroom, Audri Lawrence

Capstone Projects and Master's Theses

Technology has become a big part of the education system. Students use technology, such as tablets in their classrooms as early as preschool. There is much debate on whether or not the use of technology is needed in the elementary grades. This capstone closely examines how students are affected by the increased use of technology in the classrooms. In addition, the project explores how the intended technology affects students' development, social skills, and learning. Though technology has become an effective tool for students to use in our classrooms, it should be limited for young children, and should only be used …


A Legacy Of Homophobia: Effects Of British Colonization On Queer Rights In India And Uganda, Kelly Christensen Dec 2022

A Legacy Of Homophobia: Effects Of British Colonization On Queer Rights In India And Uganda, Kelly Christensen

Capstone Projects and Master's Theses

Globally, there are 69 countries where homosexuality is still illegal, of these 69, 36 countries are current or former British Colonies, creating a statical connection between the era of British Colonization and homophobic practices. This paper researches how moral regulations were used during the act of colonization to control and separate populations, using India and Uganda as case studies.


Jacobs Heart 5k/10k Fundraiser, Luis Mojica-Ireta Dec 2022

Jacobs Heart 5k/10k Fundraiser, Luis Mojica-Ireta

Capstone Projects and Master's Theses

Jacob’s Heart Children’s Cancer Support Services exists to improve the quality of life for families whose children have cancer. Jacob’s Heart provides counseling services, direct financial support, food assistance, and transportation services at no cost to the families they serve. Through this project of a 5k 10k fundraiser Jacob’s Heart will be able to reach a broader audience that has not been tapped into in this way, increasing the organizations awareness in Monterey County and raising funds at the same time. The fundraiser was able to raise over $25,000 for Jacob’s Heart and make new connections in Salinas for future …


Secure Human Action Recognition By Encrypted Neural Network Inference, Miran Kim, Xiaoqian Jiang, Kristin Lauter, Elkhan Ismayilzada, Shayan Shams Dec 2022

Secure Human Action Recognition By Encrypted Neural Network Inference, Miran Kim, Xiaoqian Jiang, Kristin Lauter, Elkhan Ismayilzada, Shayan Shams

Faculty Research, Scholarly, and Creative Activity

Advanced computer vision technology can provide near real-time home monitoring to support “aging in place” by detecting falls and symptoms related to seizures and stroke. Affordable webcams, together with cloud computing services (to run machine learning algorithms), can potentially bring significant social benefits. However, it has not been deployed in practice because of privacy concerns. In this paper, we propose a strategy that uses homomorphic encryption to resolve this dilemma, which guarantees information confidentiality while retaining action detection. Our protocol for secure inference can distinguish falls from activities of daily living with 86.21% sensitivity and 99.14% specificity, with an average …


Impact Of Covid-19 On Health Risk Behaviors In Northern California: A Cross-Sectional Survey, Adriana Telias, Marcelle M. Dougan, Giselle A.P. Pignotti Dec 2022

Impact Of Covid-19 On Health Risk Behaviors In Northern California: A Cross-Sectional Survey, Adriana Telias, Marcelle M. Dougan, Giselle A.P. Pignotti

Faculty Research, Scholarly, and Creative Activity

The COVID-19 pandemic has been disruptive, unevenly impacting health behaviors in different geographical regions and population groups. We examined how COVID-19 affected perceived changes in physical activity, sleep, and diet and the impact of socio-demographic variables on a calculated health risk behavior score. In this cross-sectional study, 505 residents of northern California completed a web-based survey from August to November of 2020. Chi-square and multivariable linear regression analyses examined the association between socio-demographic variables and the health risk behavior score. Approximately 84 % of respondents experienced at least one unfavorable behavior change after the pandemic, with 49.5 % indicating a …


Meeting The 24-H Movement Guidelines And Health-Related Outcomes Among Youth With Autism Spectrum Disorder: A Seven-Country Observational Study, Chunxiao Li, Justin A. Haegele, Fenghua Sun, Maria Luiza Tanure Alves, Stefanie Hwee Chee Ang, Jihyun Lee, Kwok Ng, Isabella Dos Santos Alves, Sean Healy, Wendy Yajun Huang, Pauli Rintala, Jernice Sing Yee Tan, Yandan Wu, Hannah Yang, Eija Kärnä, Hyokju Maeng, André Lisandro Schliemann, Ding Ding Dec 2022

Meeting The 24-H Movement Guidelines And Health-Related Outcomes Among Youth With Autism Spectrum Disorder: A Seven-Country Observational Study, Chunxiao Li, Justin A. Haegele, Fenghua Sun, Maria Luiza Tanure Alves, Stefanie Hwee Chee Ang, Jihyun Lee, Kwok Ng, Isabella Dos Santos Alves, Sean Healy, Wendy Yajun Huang, Pauli Rintala, Jernice Sing Yee Tan, Yandan Wu, Hannah Yang, Eija Kärnä, Hyokju Maeng, André Lisandro Schliemann, Ding Ding

Faculty Research, Scholarly, and Creative Activity

Background: Meeting daily guidelines for physical activity, screen time, and sleep duration is associated with a host of health indicators for youth. In this cross-sectional observational study, we investigated the associations between adherence to the movement guidelines and health-related outcomes among youth with autism spectrum disorder (ASD). Methods: Parents of youth with ASD (10–17 years) from seven countries and regions were invited to provide online proxy-reports for child’s movement behaviors (i.e., physical activity, sleep and screen time), and health-related outcomes (i.e., body mass index [BMI], general health, and quality of life). A series of multiple linear regression analyses were used …


The Flavor Profiles Of Highland Barley Fermented With Different Mushroom Mycelium, Kai Wang, Cuicui Yang, Ziyan Dai, Zhenxiang Wen, Yin Liu, Xi Feng, Ying Liu, Wen Huang Dec 2022

The Flavor Profiles Of Highland Barley Fermented With Different Mushroom Mycelium, Kai Wang, Cuicui Yang, Ziyan Dai, Zhenxiang Wen, Yin Liu, Xi Feng, Ying Liu, Wen Huang

Faculty Research, Scholarly, and Creative Activity

Highland barley was fermented with Cordyceps militaris, Stropharia rugoso-annulata, Morchella esculenta, Schizophyllum commune and Tremella sanguinea. The flavor profiles were investigated by electronic nose (E-nose), headspace solid-phase microextraction gas chromatography-mass spectrometry (HS-SPME-GC-MS) and sensory evaluation by train panel. Fermentation with mushroom mycelium was able to change the aroma profile of highland barley. The original strong grassy taste was reduced due to a decrease in hexanal, decanal and 2-pentylfuran, and new aromatic flavors (floral, sweet and mushroom fragrance) were acquired after fermentation. The overall flavor of the fermented highland barley varied with mushroom strains. Schizophyllum commune gave a heavier sour taste …


Psychometric Evaluation Of The Muscle Dysmorphic Disorder Inventory (Mddi) Among Gender-Expansive People, Emilio J. Compte, Chloe J. Cattle, Jason M. Lavender, Tiffany A. Brown, Stuart B. Murray, Matthew R. Capriotti, Annesa Flentje, Micah E. Lubensky, Juno Obedin-Maliver, Mitchell R. Lunn, Jason M. Nagata Dec 2022

Psychometric Evaluation Of The Muscle Dysmorphic Disorder Inventory (Mddi) Among Gender-Expansive People, Emilio J. Compte, Chloe J. Cattle, Jason M. Lavender, Tiffany A. Brown, Stuart B. Murray, Matthew R. Capriotti, Annesa Flentje, Micah E. Lubensky, Juno Obedin-Maliver, Mitchell R. Lunn, Jason M. Nagata

Faculty Research, Scholarly, and Creative Activity

Purpose: Muscle dysmorphia is generally classified as a specific form of body dysmorphic disorder characterized by a pathological drive for muscularity and the preoccupation that one is too small or not sufficiently muscular. The majority of research on the condition has been conducted in cisgender men with a paucity of literature on gender minority people, a population that is at risk for muscle dysmorphia. One of the most widely used measures of muscle dysmorphia symptoms, the Muscle Dysmorphic Disorder Inventory (MDDI), has not been psychometrically validated for use in gender minority samples, the aim of the present study. Methods: We …


Promoting Permanency In Families With Parental Substance Misuse: Lessons From A Process Evaluation Of A Multi-System Program, Karla Shockley Mccarthy, Jennifer Price Wolf, Elinam Dellor Dec 2022

Promoting Permanency In Families With Parental Substance Misuse: Lessons From A Process Evaluation Of A Multi-System Program, Karla Shockley Mccarthy, Jennifer Price Wolf, Elinam Dellor

Faculty Research, Scholarly, and Creative Activity

Background: Families affected by substance misuse are at increased risk for child maltreatment and child welfare system involvement. The Enhancing Permanency in Children and Families (EPIC) program uses four evidence-based and informed multi-system practices to promote safety and permanency outcomes for children involved with the child welfare system due to parental substance misuse: 1) Peer Recovery Support (PRS), 2) Family Treatment Drug Court (FTDC), 3) Medications for Opioid Use Disorder (MOUD) and 4) Nurturing Parent Program (NPP) relational skill-building. The purpose of the current study was to identify barriers, facilitators, and lessons learned in the implementation of and client engagement …


Traffic Restrictions During The 2008 Olympic Games Reduced Urban Heat Intensity And Extent In Beijing, Bo Yang, Hongxing Liu, Emily L. Kang, Timothy L. Hawthorne, Susanna T.Y. Tong, Song Shu, Min Xu Dec 2022

Traffic Restrictions During The 2008 Olympic Games Reduced Urban Heat Intensity And Extent In Beijing, Bo Yang, Hongxing Liu, Emily L. Kang, Timothy L. Hawthorne, Susanna T.Y. Tong, Song Shu, Min Xu

Faculty Research, Scholarly, and Creative Activity

Satellite thermal remote sensing has been utilized to examine the urban heat dynamics in relation to the urban traffic restriction policy. During the 2008 Olympic Games in Beijing, the traffic volume was approximately cut off by half through the road space rationing. Based on daily MODIS satellite thermal observations on the surface temperature, statistical models were developed to analyze the contribution of traffic volume reduction to the urban heat intensity and spatial extent. Our analyses show that cutting off half of the traffic volume has led to a marked decrease in the mean surface temperature by 1.5–2.4 °C and shrinkage …


Lack Of Consensus Among Healthcare Professionals At A Large Academic Medical Center On The Use Of Exome Sequencing For Prenatal Diagnosis, Kylie Johnson, Hadi Erfani, Mohamad Ali Maktabi, Ignatia Van Den Veyver, Salma Nassef Dec 2022

Lack Of Consensus Among Healthcare Professionals At A Large Academic Medical Center On The Use Of Exome Sequencing For Prenatal Diagnosis, Kylie Johnson, Hadi Erfani, Mohamad Ali Maktabi, Ignatia Van Den Veyver, Salma Nassef

Center for Medical Ethics and Health Policy Staff Publications

Prenatal exome sequencing (ES) is increasingly used for prenatal diagnosis because emerging data indicate it has incremental diagnostic benefit in pregnancies with fetal anomalies without identified genetic abnormalities by karyotyping and chromosomal microarray analysis. The aim of this study was to evaluate the medical community's attitude toward the clinical utility and use of exome sequencing for prenatal diagnosis and to address differences in attitudes and responses by type of practitioner, level of training, and years passed since last full-time training. We analyzed the answers of 109 trainees and professionals in the fields of genetic counseling, laboratory science, and medicine to …


Healthcare Mistreatment, State-Level Policy Protections, And Healthcare Avoidance Among Gender Minority People, Kristen D. Clark, Sean Luong, Mitchell R. Lunn, Elena Flowers, Esmaeil Bahalkeh, Micah E. Lubensky, Matthew R. Capriotti, Juno Obedin-Maliver, Annesa Flentje Dec 2022

Healthcare Mistreatment, State-Level Policy Protections, And Healthcare Avoidance Among Gender Minority People, Kristen D. Clark, Sean Luong, Mitchell R. Lunn, Elena Flowers, Esmaeil Bahalkeh, Micah E. Lubensky, Matthew R. Capriotti, Juno Obedin-Maliver, Annesa Flentje

Faculty Research, Scholarly, and Creative Activity

Introduction: This study examined whether past experiences of mistreatment in healthcare were associated with greater healthcare avoidance due to anticipated mistreatment among gender minority (GM) people. We evaluated whether state-level healthcare policy protections moderated this relationship. Methods: Data from the 2018 Annual Questionnaire of The PRIDE Study, a national longitudinal study on sexual and gender minority people’s health, were used in these analyses. Logistic regression modeling tested relationships between lifetime healthcare mistreatment due to gender identity or expression and past-year healthcare avoidance due to anticipated mistreatment among GM participants. Interactions between lifetime healthcare mistreatment and state-level healthcare policy protections and …


Leaving More Than Footprints: Anthropogenic Nutrient Subsidies To A Protected Area, A. S. Guerra, A. Bui, M. Klope, D. A. Orr, S. A. Shaffer, H. S. Young Dec 2022

Leaving More Than Footprints: Anthropogenic Nutrient Subsidies To A Protected Area, A. S. Guerra, A. Bui, M. Klope, D. A. Orr, S. A. Shaffer, H. S. Young

Faculty Research, Scholarly, and Creative Activity

Mobile animals that traverse ecosystem boundaries can fundamentally reshape environments by providing critical nutrient and energy inputs to the ecosystems they inhabit. In particular, aggregations of seabirds often transform coastal and island ecosystems through large amounts of nutrient-rich guano deposition. Anthropogenically driven losses of these subsidies can occur through changes in abundance of mobile species, including seabirds, and have been shown to drive whole-scale ecosystem state change on islands. However, even though many species that forage on anthropogenic food sources are highly mobile and may thus play important roles in moving nutrients from urban systems to otherwise conserved ecosystems, the …


A Multitask Deep Learning Approach For Pulmonary Embolism Detection And Identification, Xiaotian Ma, Emma C. Ferguson, Xiaoqian Jiang, Sean I. Savitz, Shayan Shams Dec 2022

A Multitask Deep Learning Approach For Pulmonary Embolism Detection And Identification, Xiaotian Ma, Emma C. Ferguson, Xiaoqian Jiang, Sean I. Savitz, Shayan Shams

Faculty Research, Scholarly, and Creative Activity

Pulmonary embolism (PE) is a blood clot traveling to the lungs and is associated with substantial morbidity and mortality. Therefore, rapid diagnoses and treatments are essential. Chest computed tomographic pulmonary angiogram (CTPA) is the gold standard for PE diagnoses. Deep learning can enhance the radiologists’workflow by identifying PE using CTPA, which helps to prioritize important cases and hasten the diagnoses for at-risk patients. In this study, we propose a two-phase multitask learning method that can recognize the presence of PE and its properties such as the position, whether acute or chronic, and the corresponding right-to-left ventricle diameter (RV/LV) ratio, thereby …


A Comprehensive Artificial Intelligence Framework For Dental Diagnosis And Charting, Tanjida Kabir, Chun Teh Lee, Luyao Chen, Xiaoqian Jiang, Shayan Shams Dec 2022

A Comprehensive Artificial Intelligence Framework For Dental Diagnosis And Charting, Tanjida Kabir, Chun Teh Lee, Luyao Chen, Xiaoqian Jiang, Shayan Shams

Faculty Research, Scholarly, and Creative Activity

Background: The aim of this study was to develop artificial intelligence (AI) guided framework to recognize tooth numbers in panoramic and intraoral radiographs (periapical and bitewing) without prior domain knowledge and arrange the intraoral radiographs into a full mouth series (FMS) arrangement template. This model can be integrated with different diseases diagnosis models, such as periodontitis or caries, to facilitate clinical examinations and diagnoses. Methods: The framework utilized image segmentation models to generate the masks of bone area, tooth, and cementoenamel junction (CEJ) lines from intraoral radiographs. These masks were used to detect and extract teeth bounding boxes utilizing several …


Deep Immunophenotyping Reveals Endometriosis Is Marked By Dysregulation Of The Mononuclear Phagocytic System In Endometrium And Peripheral Blood, Júlia Vallvé-Juanico, Ashley F. George, Sushmita Sen, Reuben Thomas, Min Gyoung Shin, Divyashree Kushnoor, Joshua J. Vásquez, Kim Chi Vo, Juan C. Irwin, Nadia R. Roan, Alexis J. Combes, Linda C. Giudice Dec 2022

Deep Immunophenotyping Reveals Endometriosis Is Marked By Dysregulation Of The Mononuclear Phagocytic System In Endometrium And Peripheral Blood, Júlia Vallvé-Juanico, Ashley F. George, Sushmita Sen, Reuben Thomas, Min Gyoung Shin, Divyashree Kushnoor, Joshua J. Vásquez, Kim Chi Vo, Juan C. Irwin, Nadia R. Roan, Alexis J. Combes, Linda C. Giudice

Faculty Research, Scholarly, and Creative Activity

Background: Endometriosis is a chronic, estrogen-dependent disorder where inflammation contributes to disease-associated symptoms of pelvic pain and infertility. Immune dysfunction includes insufficient immune lesion clearance, a pro-inflammatory endometrial environment, and systemic inflammation. Comprehensive understanding of endometriosis immune pathophysiology in different hormonal milieu and disease severity has been hampered by limited direct characterization of immune populations in endometrium, blood, and lesions. Simultaneous deep phenotyping at single-cell resolution of complex tissues has transformed our understanding of the immune system and its role in many diseases. Herein, we report mass cytometry and high dimensional analyses to study immune cell phenotypes, abundance, activation states, …


Examining The Differential Protective Effects Of Women's Spirituality And Religiosity On Alcohol And Marijuana Use By Sexual Identity, Laurie A. Drabble, Amy A. Mericle, Cat Munroe, Alison Cerezo, Katherine J. Karriker-Jaffe, Tonda L. Hughes, Karen F. Trocki Dec 2022

Examining The Differential Protective Effects Of Women's Spirituality And Religiosity On Alcohol And Marijuana Use By Sexual Identity, Laurie A. Drabble, Amy A. Mericle, Cat Munroe, Alison Cerezo, Katherine J. Karriker-Jaffe, Tonda L. Hughes, Karen F. Trocki

Faculty Research, Scholarly, and Creative Activity

The current study explored how religiosity and spirituality may differentially influence substance use by sexual identity based on a sample of adult sexual minority women (SMW; n = 437 lesbian; n = 323 bisexual) relative to a heterosexual comparison sample (n = 636). We examined three questions: (1) whether spirituality was differentially associated with alcohol and marijuana use by sexual identity; (2) whether religiosity was differentially associated with alcohol and marijuana use by sexual identity; (3) whether observed differences between spirituality or religiosity and substance use by sexual identity persisted after adjusting for religious environment. Measures included spirituality (importance of …


Influence Of Restorative Practices On The Middle-School Classroom, As Reported By Teachers: A Qualitative Case Study, Julia Y. Andrews Dec 2022

Influence Of Restorative Practices On The Middle-School Classroom, As Reported By Teachers: A Qualitative Case Study, Julia Y. Andrews

Electronic Theses and Dissertations

The purpose of this qualitative case study was to examine middle school teachers’ perceptions of the influence that restorative practices have on the middle school classroom environment. For the purpose of this study, seven middle school teachers were selected who have implemented restorative practices in their middle school classrooms to provide feedback. Findings suggest that overall restorative practices have a positive influence on the classroom. The findings from this study can be used with teachers, administrators, counselors, parents, and school and district support staff to help create a positive campus culture between students and adults in middle school classrooms. The …


Qualitatively Exploring The Impact Of A Relationship-Centered Communication Skills Training Program In Improving Patient Perceptions Of Care, Marie C. Haverfield, Robert Victor, Brenda Flores, Jonathan Altamirano, Magali Fassiotto, Merisa Kline, Barbette Weimer-Elder Dec 2022

Qualitatively Exploring The Impact Of A Relationship-Centered Communication Skills Training Program In Improving Patient Perceptions Of Care, Marie C. Haverfield, Robert Victor, Brenda Flores, Jonathan Altamirano, Magali Fassiotto, Merisa Kline, Barbette Weimer-Elder

Faculty Research, Scholarly, and Creative Activity

Objective: To explore qualitative patient experience comments before and after a relationship-centered communication skills training to understand patient experience, program impact, and opportunities for improvement. Methods: Qualitative patient experience evaluation data was captured from January 2016 to December 2018 for 483 health care clinicians who participated in the skills training. A random sampling of available open-ended patient comments (N = 33,223) were selected pre-training (n = 668) and post-training (n = 566). Comments were coded for valence (negative/neutral/positive), generality versus specificity, and based on 12 communication behaviors reflective of training objectives. Results: No significant difference was found in the valence …


Diabetes Family-Inclusion Education In The Outpatient Clinic, Sheryl Lyn Wright Dec 2022

Diabetes Family-Inclusion Education In The Outpatient Clinic, Sheryl Lyn Wright

Electronic Theses and Dissertations

Patient education is critical for the regulation of Type II Diabetes. This study evaluated 39 adults ≥ 40 years old with T2D and a HgbA1c level of ≥ 7.0%, including 27 women and 12 men aged 40 to 74. The participants were divided into two separate groups. The first group (19) diagnosed with T2D had no formal disease management education but were given videos on diabetes education to watch alone. The second group (202) was given family-inclusion diabetes education through videos. The hypothesis was that individuals who watched educational videos with family would have a more significant HgbA1c decrease than …


Understanding The Role Of Faculty Advising In Graduate Allied Healthcare Profession Programs As Practitioners Transition To Professor, Lillie Marie Barnett Thomas Dec 2022

Understanding The Role Of Faculty Advising In Graduate Allied Healthcare Profession Programs As Practitioners Transition To Professor, Lillie Marie Barnett Thomas

Electronic Theses and Dissertations

Individuals in allied healthcare professions continue to see growth in all areas, including clinical practice and higher education. Leaders at the university level, alongside leadership within allied healthcare accreditation bodies for disciplines like athletic training, occupational therapy, physical therapy, and speech-language pathology, maintain the need to grow the professions through master’s and doctoral degree programs. With the growth, many working practitioners move from clinical practice to academia with little to no experience or understanding of higher education and all the responsibilities of the job. This quantitative research study used a purposive sampling of allied healthcare professionals across the United States …


Best Practices In Disaster Public Communications: Evacuation Alerting And Social Media, Frannie Edwards, Kaikai Liu, Amanda Lee Hughes, Jerry Zeyo Gao, Dan Goodrich, Alan Barner, Robert Herrera Dec 2022

Best Practices In Disaster Public Communications: Evacuation Alerting And Social Media, Frannie Edwards, Kaikai Liu, Amanda Lee Hughes, Jerry Zeyo Gao, Dan Goodrich, Alan Barner, Robert Herrera

Mineta Transportation Institute

This research project examines the current state of the practice for disaster public communication, the distrust of government, the training available to public information officers, and the literature available to guide the design of effective public outreach messaging, especially for rapid on-set events. Growing distrust in government had led to lack of public confidence in public agency messaging during emergencies, yet public agency public information officers are using multiple pathways, including both traditional and social media resources, to try to reach impacted communities effectively. The introduction explains the development of wildfire events in the West and their context. A literature …


Characteristics Of Antifungal Utilization For Hospitalized Children In The United States., Lourdes Eguiguren, Brian R. Lee, Jason G. Newland, Matthew P. Kronman, Adam L. Hersh, Jeffrey S. Gerber, Grace M. Lee, Hayden T. Schwenk Dec 2022

Characteristics Of Antifungal Utilization For Hospitalized Children In The United States., Lourdes Eguiguren, Brian R. Lee, Jason G. Newland, Matthew P. Kronman, Adam L. Hersh, Jeffrey S. Gerber, Grace M. Lee, Hayden T. Schwenk

Manuscripts, Articles, Book Chapters and Other Papers

Objective: To characterize antifungal prescribing patterns, including the indication for antifungal use, in hospitalized children across the United States.

Design: We analyzed antifungal prescribing data from 32 hospitals that participated in the SHARPS Antibiotic Resistance, Prescribing, and Efficacy among Children (SHARPEC) study, a cross-sectional point-prevalence survey conducted between June 2016 and December 2017.

Methods: Inpatients aged < 18 years with an active systemic antifungal order were included in the analysis. We classified antifungal prescribing by indication (ie, prophylaxis, empiric, targeted), and we compared the proportion of patients in each category based on patient and antifungal characteristics.

Results: Among 34,927 surveyed patients, 2,095 (6%) received at least 1 systemic antifungal and there were 2,207 antifungal prescriptions. Most patients had an underlying oncology or bone marrow transplant diagnosis (57%) or were premature (13%). The most prescribed antifungal was fluconazole (48%) and the …


Discovery And Systematic Characterization Of Risk Variants And Genes For Coronary Artery Disease In Over A Million Participants, Krishna G Aragam, Tao Jiang, Anuj Goel, Stavroula Kanoni, Brooke N Wolford, Deepak S Atri, Elle M Weeks, Minxian Wang, George Hindy, Wei Zhou, Christopher Grace, Carolina Roselli, Nicholas A Marston, Frederick K Kamanu, Ida Surakka, Loreto Muñoz Venegas, Paul Sherliker, Satoshi Koyama, Kazuyoshi Ishigaki, Bjørn O Åsvold, Michael R Brown, Ben Brumpton, Paul S De Vries, Olga Giannakopoulou, Panagiota Giardoglou, Daniel F Gudbjartsson, Ulrich Güldener, Syed M Ijlal Haider, Anna Helgadottir, Maysson Ibrahim, Adnan Kastrati, Thorsten Kessler, Theodosios Kyriakou, Tomasz Konopka, Ling Li, Lijiang Ma, Thomas Meitinger, Sören Mucha, Matthias Munz, Federico Murgia, Jonas B Nielsen, Markus M Nöthen, Shichao Pang, Tobias Reinberger, Gavin Schnitzler, Damian Smedley, Gudmar Thorleifsson, Moritz Von Scheidt, Jacob C Ulirsch, Biobank Japan, Epic-Cvd, David O Arnar, Noël P Burtt, Maria C Costanzo, Jason Flannick, Kaoru Ito, Dong-Keun Jang, Yoichiro Kamatani, Amit V Khera, Issei Komuro, Iftikhar J Kullo, Luca A Lotta, Christopher P Nelson, Robert Roberts, Gudmundur Thorgeirsson, Unnur Thorsteinsdottir, Thomas R Webb, Aris Baras, Johan L M Björkegren, Eric Boerwinkle, George Dedoussis, Hilma Holm, Kristian Hveem, Olle Melander, Alanna C Morrison, Marju Orho-Melander, Loukianos S Rallidis, Arno Ruusalepp, Marc S Sabatine, Kari Stefansson, Pierre Zalloua, Patrick T Ellinor, Martin Farrall, John Danesh, Christian T Ruff, Hilary K Finucane, Jemma C Hopewell, Robert Clarke, Rajat M Gupta, Jeanette Erdmann, Nilesh J Samani, Heribert Schunkert, Hugh Watkins, Cristen J Willer, Panos Deloukas, Sekar Kathiresan, Adam S Butterworth, Cardiogramplusc4d Consortium Dec 2022

Discovery And Systematic Characterization Of Risk Variants And Genes For Coronary Artery Disease In Over A Million Participants, Krishna G Aragam, Tao Jiang, Anuj Goel, Stavroula Kanoni, Brooke N Wolford, Deepak S Atri, Elle M Weeks, Minxian Wang, George Hindy, Wei Zhou, Christopher Grace, Carolina Roselli, Nicholas A Marston, Frederick K Kamanu, Ida Surakka, Loreto Muñoz Venegas, Paul Sherliker, Satoshi Koyama, Kazuyoshi Ishigaki, Bjørn O Åsvold, Michael R Brown, Ben Brumpton, Paul S De Vries, Olga Giannakopoulou, Panagiota Giardoglou, Daniel F Gudbjartsson, Ulrich Güldener, Syed M Ijlal Haider, Anna Helgadottir, Maysson Ibrahim, Adnan Kastrati, Thorsten Kessler, Theodosios Kyriakou, Tomasz Konopka, Ling Li, Lijiang Ma, Thomas Meitinger, Sören Mucha, Matthias Munz, Federico Murgia, Jonas B Nielsen, Markus M Nöthen, Shichao Pang, Tobias Reinberger, Gavin Schnitzler, Damian Smedley, Gudmar Thorleifsson, Moritz Von Scheidt, Jacob C Ulirsch, Biobank Japan, Epic-Cvd, David O Arnar, Noël P Burtt, Maria C Costanzo, Jason Flannick, Kaoru Ito, Dong-Keun Jang, Yoichiro Kamatani, Amit V Khera, Issei Komuro, Iftikhar J Kullo, Luca A Lotta, Christopher P Nelson, Robert Roberts, Gudmundur Thorgeirsson, Unnur Thorsteinsdottir, Thomas R Webb, Aris Baras, Johan L M Björkegren, Eric Boerwinkle, George Dedoussis, Hilma Holm, Kristian Hveem, Olle Melander, Alanna C Morrison, Marju Orho-Melander, Loukianos S Rallidis, Arno Ruusalepp, Marc S Sabatine, Kari Stefansson, Pierre Zalloua, Patrick T Ellinor, Martin Farrall, John Danesh, Christian T Ruff, Hilary K Finucane, Jemma C Hopewell, Robert Clarke, Rajat M Gupta, Jeanette Erdmann, Nilesh J Samani, Heribert Schunkert, Hugh Watkins, Cristen J Willer, Panos Deloukas, Sekar Kathiresan, Adam S Butterworth, Cardiogramplusc4d Consortium

Faculty, Staff and Student Publications

The discovery of genetic loci associated with complex diseases has outpaced the elucidation of mechanisms of disease pathogenesis. Here we conducted a genome-wide association study (GWAS) for coronary artery disease (CAD) comprising 181,522 cases among 1,165,690 participants of predominantly European ancestry. We detected 241 associations, including 30 new loci. Cross-ancestry meta-analysis with a Japanese GWAS yielded 38 additional new loci. We prioritized likely causal variants using functionally informed fine-mapping, yielding 42 associations with less than five variants in the 95% credible set. Similarity-based clustering suggested roles for early developmental processes, cell cycle signaling and vascular cell migration and proliferation in …


Financial Literacy Among Buffalo State College Undergraduate Students, Toni Martinucci Dec 2022

Financial Literacy Among Buffalo State College Undergraduate Students, Toni Martinucci

Public Administration Master’s Projects

Financial literacy can be complex and difficult for college students to comprehend. Many students struggle to afford college and are faced with large amounts of student loan debt. Financial awareness needs to be addressed early on for students to make informed decisions about college costs, student debt, and financial aid. However, financial aid applications, terms and conditions, and eligibility requirements are difficult for many students to comprehend on their own. The purpose of this study is to access financial literacy among undergraduate students at Buffalo State College. A quantitative approach is used in this study by implementing a web-based cross-sectional …


The Effect On Mood Of Social Media Posting Among People With Mental Illnesses, Andrew Croiter Dec 2022

The Effect On Mood Of Social Media Posting Among People With Mental Illnesses, Andrew Croiter

Student Theses

There are studies that have examined how the use of social media affects people who have been diagnosed with a mental illness. However, studies that focus specifically on changes in mood after posting on social media among people with mental illnesses is absent from the literature. The present study sought to fill that gap in research by surveying 250 participants who have been diagnosed with a mental illness and testing whether there was a change in mood after posting on social media. The results concluded that there was a significant improvement in overall negative mood. There was no significant effect …


Traumatized Defendants, Troubled Attorneys: The Impact Of Vicarious Trauma On The Defense Attorney-Client Relationship, Charise Peters Dec 2022

Traumatized Defendants, Troubled Attorneys: The Impact Of Vicarious Trauma On The Defense Attorney-Client Relationship, Charise Peters

Student Theses

Approximately 90% of justice-involved youth have experienced some form of trauma by the time they become involved in the justice system, and attorneys report being negatively impacted by their work with trauma-exposed populations generally. Yet, research has not focused on how varying degrees of youth trauma can impact attorney decisions and if that differs based on youth race. This study, therefore, explored vicarious trauma and its impact on juvenile defense attorneys, including how an attorney’s experience of vicarious trauma impacts case handling and perception of their youth client and how that differs based on client race and trauma history. We …


The Impact Of Pharmacogenetics On Oral Fluid Steady State Drug Testing Results, Aliya D. Lewis Dec 2022

The Impact Of Pharmacogenetics On Oral Fluid Steady State Drug Testing Results, Aliya D. Lewis

Student Theses

Pharmacogenetics refers to the relationship between phenotypic variation in metabolism and response to certain drugs. The interface of pharmacogenetics and forensic toxicology is not well explored. A major component of the opioid metabolic pathway has to do with a family of cytochromes called cytochrome P450 (CYP450). CYP450 refers to a general family of enzymes capable of catalyzing the oxidative biotransformation of lipophilic substances, CYPs are further categorized into families and sub-families (Roller, 2015; Zanger & Schwab, 2013). The gene CYP2D6 belongs to the CYP2 family which is responsible for the biotransformation of xenobiotics. This study looked at the effect of …


The Cultic Lifecycle: A Thematic Analysis Of Fulfillment And Fear In Cult Membership, Shaelen Grant Dec 2022

The Cultic Lifecycle: A Thematic Analysis Of Fulfillment And Fear In Cult Membership, Shaelen Grant

Student Theses

Prior research on susceptibility to cult recruitment has focused predominately on psychopathological risk factors, such as a prior personality disorder diagnosis and psychiatric and addictive disorders (Feldman & Johnson, 1995; Rousselet et al., 2017). While such studies contribute valuable information, they also inadvertently pathologize cult members. Furthermore, this focus has led to the overlooking of a more crucial question: what basic human desires does cult membership fulfill that cult leaders and recruiters exploit, to recruit and keep members in cults? To address this dearth, research team members interviewed 52 former cult members (N=52) from a variety of groups (e.g., Christian-based, …


Perception Of Police And The Mediation Of Memory Distortion Via Trauma: Body Worn Camera Footage Of An Emotional Police-Citizen Encounter, Arlyn Abreu Dec 2022

Perception Of Police And The Mediation Of Memory Distortion Via Trauma: Body Worn Camera Footage Of An Emotional Police-Citizen Encounter, Arlyn Abreu

Student Theses

This present study calls to question the objectivity of police body-worn camera (BWC) footage. Proponents assume that BWCs will be a panacea in a climate of heightened tensions between officers and communities. In spite of this, our findings challenge the rhetoric, and the purpose BWC is intended to serve. We explored its implications on memory distortion by posing two questions (a) can people come to remember BWC footage as more traumatic than they initially experienced (b) to what degree can external information and internal influences impact peoples' judgment about a traumatic event. We addressed both questions in this two-part study, …